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Researchers at Huazhong University of Science and Technology conducted a study on the treatment of complex renal calculi using a combination of standard PCNL, visual needle nephroscope, and holmium YAG laser. The study involved 62 patients with complex kidney stones, and the results showed a stone-free rate of 93.5% after the primary operation. The researchers concluded that this optimized approach was safe, effective, and feasible for treating complex renal calculi. The study was published in BMC Urology and can be accessed for further information. [Extracted from the article]

Researchers at People's Hospital Yichun City in Jiangxi, China, conducted a meta-analysis comparing bipolar transurethral enucleation of the prostate (B-TUEP) and holmium laser enucleation of the prostate (HoLEP) for treating benign prostatic hyperplasia (BPH). The study included 14 studies with 2317 BPH patients and found that HoLEP had advantages in terms of catheterization time, urinary retention, hemoglobin drop, overall complications, and long-term functional outcomes. The research concluded that HoLEP may be more beneficial for BPH patients, especially for those with larger prostates. The study has been peer-reviewed and provides valuable insights into surgical approaches for BPH treatment. [Extracted from the article]

A study conducted by Sungkyunkwan University School of Medicine in Seoul, South Korea, focused on developing a deep learning-based predictive model for improvement after holmium laser enucleation of the prostate (HoLEP) for male lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH). The study utilized a deep neural network (DNN) for multiclass classification to predict changes in maximum flow rate (MFR) and voiding efficiency (VE) post-surgery. Results showed that the DNN model outperformed other machine learning models in predicting symptom improvement, providing valuable insights for clinicians managing patients with LUTS/BPH. [Extracted from the article]

A recent study conducted at Beijing Hospital compared the clinical efficacy and safety of the superpulse thulium fiber laser (SP TFL) and the holmium laser for ureteroscopic lithotripsy in treating upper urinary tract calculi. The research aimed to evaluate the stone-free rate, duration of surgery, postoperative hospital stay, and other outcomes in patients undergoing treatment with either laser. The study, registered with ChiCTR, concluded that the SP TFL shows potential as a substitute for the holmium laser in ureteroscopy. [Extracted from the article]

Researchers at Nantong University in Jiangsu, China conducted a retrospective study comparing the effects of modified holmium laser enucleation of the prostate (HoLEP) versus traditional HoLEP on urinary incontinence in elderly patients. The study found that the modified technique resulted in lower rates of urinary incontinence at 3 and 6 months post-surgery, with significant differences in membranous urethral length and enucleated prostate weight. The researchers concluded that the modified HoLEP technique is safe and effective for improving urine control, with better outcomes in residual prostate volume and maximum urine flow rate. [Extracted from the article]

Researchers from the University of Miami conducted a study on the efficacy and safety of combining High-Intensity Focused Ultrasound (HIFU) and Holmium Laser Enucleation of the Prostate (HoLEP) for treating patients with localized prostate cancer and prostate volumes greater than 60g. The study found that the combined treatment showed lower PSA metrics but no significant differences in recurrence rates compared to HIFU-monotherapy. The research concluded that combining HoLEP and HIFU can be a safe treatment option for patients with large prostate volumes without compromising early oncological outcomes. [Extracted from the article]

Researchers at the University of Miami conducted a study to evaluate the efficacy and safety of Holmium laser enucleation of the prostate (HoLEP) in patients with obstructive uropathy (OU) due to bladder outlet obstruction (BOO). The study found that HoLEP was effective and safe in patients with OU, although they were at a higher risk of postoperative acute kidney injury. The research, which has been peer-reviewed, concluded that patients with OU showed significant improvement in serum creatinine levels postoperatively. [Extracted from the article]

A study conducted at the Northern Ontario School of Medicine compared the use of second-generation MOSES 2.0 technology to MOSES 1.0 technology for holmium laser enucleation of the prostate (HoLEP) in patients with benign prostatic hyperplasia (BPH). The research found that patients who underwent HoLEP with MOSES 2.0 technology had shorter enucleation and hemostasis times, lower laser energy usage, and comparable postoperative outcomes to those who underwent HoLEP with MOSES 1.0 technology. The study concluded that HoLEP with second-generation MOSES 2.0 technology is a safe and effective treatment option for BPH. [Extracted from the article]

A study conducted at Marche Polytechnic University in Ancona, Italy, focused on the significance of Hounsfield Units (HU) in predicting outcomes in retrograde intrarenal surgery (RIRS) using Holmium and Thulium fiber lasers for ureteroscopy procedures. The research found that stone size, lower pole stones (LPS), and the type of laser used were predictors of residual fragments (RF) after RIRS, regardless of stone density. The study concluded that HU should be considered an important parameter in predicting stone-free rates (SFR) postoperatively. The findings were published in the World Journal of Urology and have been peer-reviewed. [Extracted from the article]

A recent study conducted at the University of Rochester Medical Center focused on identifying risk factors associated with positive urine cultures following holmium laser enucleation of the prostate (HoLEP). The research found that positive preoperative cultures were predictive of positive postoperative cultures, but there were instances of discordance between the two results. The study suggests that host factors increasing susceptibility to bacteriuria may explain these findings. For more information, the full article can be accessed through Urology Annals. [Extracted from the article]

A recent study conducted at Second Xiangya Hospital in Hunan, China, focused on analyzing the risk factors for ureteral stenosis following ureteroscopic holmium laser lithotripsy. The research identified stone diameter, stone incarceration, and hydronephrosis as independent risk factors for ureteral stenosis. A predictive model was constructed using logistic regression analysis, showing high accuracy and discriminative ability in identifying high-risk groups for timely prevention of ureteral stenosis. The study's findings aim to minimize the risk of postoperative ureteral stenosis and improve patient outcomes. [Extracted from the article]

A recent study conducted by the University of Rochester in New York aimed to evaluate factors that impact continence recovery after holmium laser enucleation of the prostate (HoLEP) for surgeons early in their HoLEP experience. The study included 152 subjects with a median age of 70, and 94.7% of them recovered continence within a median of 1.6 months postoperatively. The study found that younger age and shorter enucleation time predicted faster recovery of continence. These findings contribute to our understanding of HoLEP outcomes during a surgeon's learning curve. [Extracted from the article]

A recent study conducted in Maharashtra, India compared two surgical treatments for Benign Prostatic Hyperplasia (BPH): Holmium Laser Enucleation of the Prostate (HoLEP) and bipolar resection of the prostate. The study included 60 patients and found that both procedures were equally effective in treating BPH. However, the bipolar resection of the prostate procedure had a smaller learning curve and was associated with lower costs. The study concluded that bipolar resection of the prostate is a feasible and cost-effective method for treating BPH patients. [Extracted from the article]

Researchers from "Iuliu Hatieganu" University of Medicine and Pharmacy in Cluj Napoca, Romania, conducted a study to identify predictive factors associated with transient urine incontinence (TUI) following holmium laser enucleation of the prostate (HoLEP). The study included 119 patients with benign prostatic hyperplasia (BPH), and 15.96% of them experienced postoperative TUI. Factors such as increased age, prostate volume, preoperative catheterization, high post-void residual volume, longer operative time, and resected tissue weight were found to be independent predictors of TUI. The study concluded that the incidence of TUI following HoLEP was 15.96%, with a recovery rate of 78.94% within three months post-surgery. [Extracted from the article]

A study conducted at the Mayo Clinic in Phoenix, Arizona, examined the impact of a surgical technique called early apical release (EAR) on postoperative stress urinary incontinence (SUI) in patients who underwent Holmium Laser Enucleation of the Prostate (HoLEP) for benign prostatic hyperplasia. The study proposed a novel classification of the external sphincter appearance after HoLEP, graded from 0 (best preserved) to 3 (most degraded). The results showed that lower sphincter grades were associated with improved return of continence after EAR HoLEP. This research provides new insights into the management of SUI in patients undergoing HoLEP. [Extracted from the article]

A retrospective study conducted in Guangdong, China examined the factors influencing postoperative ureteral stenosis following holmium laser lithotripsy. The study found that patients with proximal stones, large stones, longer surgical procedures, higher water intake, longer disease duration, and stone-related polyps were more likely to develop postoperative ureteral stenosis. Surgeons should consider these risk factors during preoperative evaluation and surgical planning to minimize the risk of complications. The study highlights the importance of understanding these factors in order to improve patient outcomes. [Extracted from the article]

A recent study conducted by the University of Malaya compared the use of thulium fiber laser (TFL) and high-power holmium:yttrium-aluminum-garnet (Ho:YAG) laser in same-sitting bilateral retrograde intrarenal surgery (SSB-RIRS) for kidney stones. The study found that both lasers were used equally by urologists for SSB-RIRS, with low reintervention rates and comparable safety profiles. However, the use of TFL was associated with higher odds of being stone-free bilaterally. The study also noted that bilateral lower pole and large-volume stones had higher chances of residual fragments. [Extracted from the article]

A study conducted by the University of Florence in Italy aimed to assess the rate of successful outcomes following holmium laser enucleation of the prostate (HoLEP) and identify predictors of failure. The study defined "Trifecta" as the presence of no postoperative complications within 3 months, no urinary incontinence at 3-month follow-up, and a 3-month postoperative max flow-rate greater than 15 mL/s. Out of 305 patients included in the study, 63.0% achieved Trifecta. Predictors of Trifecta failure were found to be a post-void residual (PVR) greater than or equal to 250 mL, the first surgical era, and the standard three-lobes enucleation technique. The study concluded that surgical strategy, experience, and baseline PVR are important factors in predicting outcomes. [Extracted from the article]

A recent study conducted at the University of California Irvine compared the outcomes of two surgical treatments for bladder outlet obstruction (BOO) caused by prostate enlargement: robot-assisted simple prostatectomy (RASP) and holmium laser enucleation of the prostate (HoLEP). The researchers used propensity score matching (PSM) to control for selection bias and compared preoperative, perioperative, and postoperative outcomes. They found that both RASP and HoLEP had similar outcomes in terms of stress urinary incontinence rates at 3 months. However, HoLEP resulted in shorter durations of postoperative catheterization, while RASP led to shorter hospital stays. [Extracted from the article]

A study conducted by researchers at Universidad Europea in Madrid, Spain, has examined the use of the adjustable trans-obturator male system (ATOMS) in treating stress urinary incontinence (SUI) in men following surgical treatment for benign prostatic enlargement (BPE). The study involved 40 patients who had undergone either transurethral resection (TURP) or holmium laser enucleation (HoLEP) of the prostate. The results showed that ATOMS was effective in treating SUI in these patients, with 80% achieving dryness and 45% achieving total continence after adjustment. The study suggests that ATOMS is a safe and viable option for treating SUI caused by sphincteric damage from endoscopic surgery for BPE. [Extracted from the article]

A recent study conducted by researchers at Heidelberg University in Mannheim, Germany, examined the learning curve and outcomes of holmium laser enucleation of the prostate (HoLEP) in 500 consecutive cases performed by a single surgeon. The study found that there was a slight but steady learning curve, with improvements in operation time, enucleation efficiency, and laser energy efficiency over time. However, there was no measurable learning curve in terms of blood loss, complications, length of hospital stay, and catheterization time. The researchers concluded that HoLEP using the en-bloc technique is a safe and highly effective method. [Extracted from the article]

A study conducted in Fujian, China evaluated the efficacy of Transurethral Holmium Laser Enucleation of the Prostate (HoLEP) in the treatment of benign prostatic hyperplasia (BPH) in patients aged 75 years or less. The study included 80 patients with BPH, with 30 cases undergoing HoLEP with preservation of the urethral ridge and 50 cases undergoing conventional HoLEP. The analysis showed no significant differences in various factors between the two groups, except for the immediate postoperative urinary control rate and the incidence of retrograde ejaculation, which were better in the group that underwent HoLEP with preservation of the urethral ridge. The study concluded that this technique is comparable to conventional HoLEP but can improve urinary control and reduce the incidence of retrograde ejaculation. [Extracted from the article]

A recent study conducted at Seoul National University Hospital in South Korea evaluated the efficacy and safety of holmium laser enucleation of the prostate (HoLEP) in patients with benign prostatic hyperplasia (BPH). The study followed 3,000 patients over a period of several years and found that HoLEP was effective in reducing symptoms and improving urinary flow rate. Complication rates were low, although there were cases of stress urinary incontinence and de novo stone formation. Overall, the study concluded that HoLEP is a promising treatment option for BPH with favorable outcomes. [Extracted from the article]

A recent study conducted by researchers at Chungnam National University in South Korea examined the effectiveness of self-training using a virtual reality head-mounted display simulator for acquiring surgical skills in holmium laser enucleation surgery. Thirteen medical students without prior surgical skills were trained using multimedia and a simulator. The results showed significantly improved scores and a high pass rate after the self-training, indicating that the simulator was helpful in acquiring surgical skills for this procedure. The researchers concluded that this virtual reality simulator could potentially shorten the learning curve for this technique in real clinical practice. [Extracted from the article]

A research study conducted at the Third Affiliated Hospital of Anhui Medical University in China investigated the efficacy and prognosis of transurethral holmium laser en-bloc resection of bladder tumor (HOLRBT) compared to transurethral resection of bladder tumor (TURBT) in the treatment of non-invasive bladder cancer. The study included 86 patients with non-invasive bladder cancer, with 43 patients in each treatment group. The results showed that HOLRBT had a positive effect on the treatment of non-invasive bladder cancer, leading to longer progression-free survival time and lower recurrence rates compared to TURBT. The study compared various factors such as operation time, hospital stay, bleeding volume, and lymphocyte subsets, among others. This research provides valuable insights for the treatment of bladder cancer. [Extracted from the article]

A recent study conducted at the University of Mansoura in Egypt explored a novel technique called veil sparing Holmium laser enucleation of the prostate (VS-HoLEP) to improve continence outcomes following the procedure. The study compared VS-HoLEP to standard HoLEP and found that patients who underwent VS-HoLEP had better early continence outcomes, with fewer cases of urinary incontinence and a shorter time to continence. The researchers concluded that optimizing the surgical technique could reduce the number and severity of postoperative urine leaks. This research has been peer-reviewed and published in Minerva Urology and Nephrology. [Extracted from the article]

A study conducted at the Cleveland Clinic in Ohio found that high-risk patients undergoing holmium laser enucleation of the prostate (HoLEP) for benign prostatic hyperplasia had fewer infections when given a longer course of preoperative antibiotics. The study included 407 patients, with 146 receiving a short course of antibiotics and 261 receiving a long course. The results showed that 7.6% of patients in the short course group experienced postoperative infections, compared to 1.9% in the long course group. The researchers concluded that further prospective trials are needed to determine the optimal preoperative antibiotic regimens for these patients. [Extracted from the article]

Researchers from Beth Israel Deaconess Medical Center in Boston, Massachusetts have discussed new findings in Chemicals and Chemistry related to the teaching of Holmium Laser Enucleation of the Prostate (HoLEP). HoLEP is a technique used to treat benign prostatic hyperplasia, and the researchers describe their stepwise approach for teaching this procedure as part of a structured surgical training curriculum. The study evaluates the association of their teaching method with intraoperative efficiency parameters and immediate postoperative surgical outcomes of 200 HoLEP procedures. This research has been peer-reviewed and is published in the Canadian Journal of Urology. [Extracted from the article]

A study conducted by researchers from the University of Kansas Health System compared the use of the high-power holmium:yttrium-aluminium-garnet (Ho:YAG) laser with MOSES technology to the thulium fibre laser (TFL) in mini-percutaneous nephrolithotomy (PCNL) surgeries. The study found that the Ho:YAG laser was more efficient, utilizing less energy and time, resulting in higher ablation efficiency and shorter operating time. However, there was no significant difference in stone-free rate (SFR) between the two laser platforms. The study suggests that the Ho:YAG laser may be a preferable option for mini-PCNL surgeries due to its efficiency. [Extracted from the article]

A patent application has been submitted for a new surgical laser fiber standoff arrangement that aims to prevent dust particle accumulation during laser lithotripsy procedures. The invention involves using a standoff that creates space between the laser fiber and the target, preventing contact and potential fiber degradation. The application discusses different versions of the standoff, including a non-cylindrical design that doesn't trap dust particles and a modified cylindrical standoff with a flushing system. The invention addresses the challenges posed by continuous wave Thulium fiber lasers, which generate more heat and can degrade the fiber. The application also mentions previous improvements to the standoff sleeves and methods for laser lithotripsy procedures. This patent application describes an improved optical fiber arrangement for laser surgery applications, specifically for laser lithotripsy procedures. The invention aims to prevent dust accumulation in laser surgery systems that use standoff sleeves or protective tips. The standoff sleeves are modified to prevent dust accumulation by extending on one side of or partially around the fiber, including ports for flushing out dust particles, and using materials that resist heat. The invention also allows for precise positioning of sensors or detectors at the treatment site. The patent application provides detailed claims and additional information for those interested in further research. [Extracted from the article]

A recent report discusses research on cervical intraepithelial neoplasia (CIN) and the effectiveness of different laser ablation techniques for its treatment. The study specifically focuses on the use of a holmium yttrium-aluminum-garnet (Ho:YAG) laser and its efficacy in preventing recurrence of CIN2/3. The research found that laser ablation with the Ho:YAG laser showed promising results, with a 2-year recurrence rate of 5.6%. Age was found to be a significant factor in recurrence risk, while preoperative CIN grade and HPV status did not significantly affect it. The study suggests that postoperative high-risk HPV testing should be conducted after diagnostic conization to detect recurrence. [Extracted from the article]

A study conducted by researchers at Xiamen University in Fujian, China, examined the effects of compound thermal insulation management on the recovery and comfort of patients undergoing transurethral ureteroscopic holmium laser lithotripsy. The study involved 551 patients who were randomly assigned to either an observation group or a control group. The observation group received compound thermal insulation management in addition to routine surgical care. The results showed that the observation group had higher perioperative body temperatures, better anesthetic resuscitation indicators, improved comfort and quality of life, and a lower incidence of complications compared to the control group. The study concluded that compound thermal insulation management during the procedure can improve patient outcomes. [Extracted from the article]

A study conducted in Wuzhou, China compared the effects of holmium laser lithotripsy and pneumatic lithotripsy on patients with ureteral calculi. The study found that holmium laser lithotripsy had a higher success rate for primary lithotripsy compared to pneumatic lithotripsy. Additionally, the holmium laser lithotripsy group had shorter operation times, shorter hospital stays, and lower levels of inflammatory and oxidative stress markers compared to the pneumatic lithotripsy group. The study concluded that holmium laser lithotripsy is more effective in improving the lithotripsy effect, reducing complications, and shortening recovery time for patients with ureteral stones. [Extracted from the article]

A study conducted by the University of Texas Health Science Center in San Antonio examined the utilization trends and outcomes of holmium laser enucleation of the prostate (HoLEP) compared to other surgical procedures for benign prostatic hyperplasia (BPH). The study found that despite being endorsed by the American Urological Association (AUA) and having evidence supporting its safety and efficacy, the utilization of HoLEP remains limited in the United States. However, the adoption of HoLEP has slightly increased since 2015. The underutilization of HoLEP may be due to a lack of availability and the steep learning curve associated with the procedure. [Extracted from the article]

A study conducted by the Medical College of Rzeszow University in Poland examined the impact of different power settings of the holmium laser and the flow rate of irrigation fluid on the fluid temperature during lithotripsy. The researchers used a 3D-printed model of the renal pelvicalyceal system and measured the temperature using thermography. They found that the rate of temperature increase during lithotripsy depended solely on laser power in the short term, but both laser power and irrigation flow rate influenced the maximum temperature reached during prolonged lithotripsy. This research provides valuable insights into the factors that affect intrapelvic temperature during holmium laser lithotripsy. [Extracted from the article]

A recent study conducted by researchers at the University of Rochester in New York examined the thermal profiles of the holmium laser during laser lithotripsy, a common treatment for urolithiasis. The study found that temperature generation and thermal dose delivered were highest closer to the tip of the laser fiber and were influenced by factors such as laser-on time, operator duty cycle, and location in the pelvicalyceal collecting system. The findings highlight the importance of patient safety during surgery and provide valuable insights for improving the efficiency and effectiveness of laser lithotripsy procedures. [Extracted from the article]

A recent study conducted at Indiana University examined the effects of Holmium laser enucleation of the prostate (HoLEP) on ejaculatory and erectile function. The study included 277 patients who completed pre and postoperative questionnaires. The results showed a significant decline in ejaculatory function post-HoLEP, but this decline was not found to be bothersome. However, there was no significant decline in erectile function. This research provides valuable insights into the sexual function outcomes of patients undergoing HoLEP for benign prostatic hyperplasia. [Extracted from the article]

A study conducted at Hubei Polytechnic University in Huangshi, China, investigated the use of phloroglucinol in ureteroscopic holmium laser lithotripsy (UHLL) and its effects on inflammatory response and oxidative stress. The study included 90 patients with ureteral calculi who underwent UHLL. The patients were divided into control and observation groups, with the observation group receiving phloroglucinol before and after the procedure. The use of phloroglucinol resulted in shorter operation and postoperative hematuria times, higher treatment efficacy, lower pain levels, and reduced complications. The mechanism of action may be related to the reduction of inflammatory response and oxidative stress. [Extracted from the article]

A recent study conducted at Singapore General Hospital compared the use of high-power holmium laser (HPHL) and thulium fiber laser (TFL) for endoscopic enucleation of the prostate in patients with glands larger than 80 ml. The study found that both lasers were equally effective in terms of 30-day complications. However, TFL with the en-bloc technique had a shorter operative time, leading to improved short- and medium-term functional outcomes. The study provides valuable insights for surgeons performing endoscopic enucleation of the prostate for benign prostate hyperplasia. [Extracted from the article]

Researchers from Gyeongsang National University in JinJu, South Korea, conducted a study to evaluate the clinical outcome and safety of holmium laser enucleation of the prostate (HoLEP) following transrectal ultrasound-guided prostate biopsy (TR biopsy) for the treatment of benign prostate hyperplasia. The study analyzed data from 556 patients who underwent HoLEP between 2014 and 2021. The researchers found that the perioperative parameters, safety, and functional outcomes were comparable between the group that underwent TR biopsy and the control group that did not. The study concluded that postoperative complications were not significantly different between the two groups. [Extracted from the article]

A study conducted in Maharashtra, India, examined the use of holmium laser lithotripsy in the management of difficult biliary and cystic ductal stones. The research found that choledocholithiasis, or common bile duct stone, presents a unique challenge in the management of biliary stones. The study discussed the successful use of single-operator cholangioscopy-guided holmium laser lithotripsy for the treatment of difficult biliary stones. The researchers concluded that holmium laser lithotripsy has revolutionized the management of difficult biliary stones, but its use may be limited by cost and availability of expertise. [Extracted from the article]

A new report from Reinbek, Germany presents fresh data on hyperplasia, specifically focusing on the medium-term results of Holmium Laser Enucleation of the Prostate (HoLEP) as a treatment option for lower urinary tract symptoms (LUTS) caused by benign prostate hyperplasia (BPH). The study evaluated patient-reported outcomes and potential risk factors for postoperative complications or impaired outcomes. The results showed high patient satisfaction with the procedure and low postoperative complication rates. The study also found that the questionnaire used for patient-reported outcome measurement correlated well with clinical parameters. The researchers did not identify any independent risk factors for postoperative complications. [Extracted from the article]

A study conducted by researchers at Northwestern University examined the impact of resectoscope sheath size on the outcomes of holmium laser enucleation of the prostate (HoLEP). The study compared the use of a 24F scope to a 28F scope and found that there was no significant difference in surgical duration or postoperative outcomes between the two groups. However, patients treated with the 28F scope were more likely to achieve effective same-day trial of void and had a shorter length of stay. The study suggests that if same-day discharge is part of the postoperative pathway, the 28F scope may be beneficial. [Extracted from the article]

A recent study conducted by Baylor Scott and White Health in Temple, Texas, examined the impact of frailty scores on the complications of holmium laser enucleation of the prostate (HoLEP) procedure. The study analyzed data from 837 patients and found that frail patients had a higher risk of perioperative complications, including blood transfusion, failed voiding trial, and postoperative readmission. However, both frail and nonfrail patients experienced similar functional outcomes after the procedure. The researchers suggest that frail patients should be informed about their increased risk of complications, despite the potential benefits of HoLEP. [Extracted from the article]

A new report discusses research findings on nephrolithotomy, a surgical procedure for removing kidney stones. The study compared the outcomes of three different lithotripsy techniques: combined electromagnetic with ultrasonic lithotripsy, pneumatic ballistic lithotripsy, and holmium laser lithotripsy. The study evaluated outcomes such as post-operative pain, complications, and stone clearance in 90 patients. The research concluded that laser and pneumatic lithotripsy were more effective in completely clearing stones compared to the trilogy lithotripsy technique, and laser lithotripsy also reduced the occurrence of hematuria. The study was conducted at the Department of Urology at Tabba Kidney Institute in Karachi, Pakistan. [Extracted from the article]

A recent study conducted by the University of Health Sciences investigated the impact of stone density on the success of ureterorenoscopy (URS) and retrograde intrarenal surgery (RIRS) for kidney and ureteral stones. The study included 566 patients who underwent URS or RIRS, and various factors such as stone density, size, volume, and operative time were recorded. The results showed that stone density, size, and volume were positively correlated with residual stone size and operative time. Additionally, high stone density was found to negatively affect the success of treatment, even in cases with small stone size and volume. [Extracted from the article]

A recent study conducted at the University of Miami evaluated the outcomes of holmium laser enucleation of the prostate (HoLEP) in patients with different prostate sizes. The study found that HoLEP had consistent and safe outcomes across a wide range of prostate sizes. While patients with very large prostates had a higher risk of perioperative blood transfusion and patients with small prostates had a higher risk of transient acute urinary retention, overall efficacy and safety were not significantly influenced by prostate size. The study concluded that HoLEP is a viable treatment option for patients with varying prostate sizes. [Extracted from the article]

A study conducted by Johns Hopkins University has developed and validated a nonbiohazardous benchtop simulator for Holmium laser enucleation of the prostate (HoLEP). The simulator was created using modern education theory and underwent a multicenter study involving 56 expert and novice participants. Objective metrics showed statistically significant differences between experts and novices in enucleation time, adenoma weight, and complications. A training curriculum incorporating this simulator is currently being developed. [Extracted from the article]

The patent application discusses a laser module and its methods that aim to expand treatment options for urological procedures. The module allows clinicians to independently drive multiple laser-producing assemblies, which include optical resonators and pumps that amplify light through stimulated emission. The module combines the input laser beams into an output laser beam with specific pulse energy, pulse width, and pulse repetition frequency. The application describes different embodiments of the module, including variations in pulse repetition frequencies, delays between input laser beams, and modulation of pulse energy. The module is controlled by a printed circuit board assembly. [Extracted from the article]

A recent study conducted at the National Cancer Institute in Libya examined the efficacy and safety of retrograde intrarenal surgery (RIRS) using holmium laser lithotripsy for the treatment of kidney stones. The study included 54 patients with renal calculi and found that RIRS combined with holmium laser lithotripsy was a valuable treatment option, particularly for patients with kidney stones less than or equal to 20 mm in size. The study reported a stone-free rate of 64.4% immediately after the procedure, which increased to 91.1% after one month. The overall complication rate was 9.2%, with most complications being urinary tract infections. The researchers concluded that RIRS with holmium laser lithotripsy is a safe and effective treatment for renal calculi. [Extracted from the article]