1. The association of metabolic syndrome and cognitive impairment in Jidong of China: a cross-sectional study
- Author
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Jian Lv, Xiaohui Wang, Xueyu Chen, Dong Li, Guoyong Ding, Yanru Chen, Long Ji, and Zhaoyang Tang
- Subjects
Adult ,Male ,China ,medicine.medical_specialty ,Cross-sectional study ,Epidemiology ,Endocrinology, Diabetes and Metabolism ,Population ,lcsh:Diseases of the endocrine glands. Clinical endocrinology ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Diabetes mellitus ,medicine ,Humans ,Cognitive Dysfunction ,Longitudinal Studies ,030212 general & internal medicine ,Risk factor ,education ,Abdominal obesity ,education.field_of_study ,lcsh:RC648-665 ,business.industry ,Confounding ,General Medicine ,Middle Aged ,Mental Status and Dementia Tests ,medicine.disease ,Metabolic syndrome ,Cross-Sectional Studies ,Cognitive impairment ,Obesity, Abdominal ,Hypertension ,Blood pressure ,Female ,medicine.symptom ,business ,030217 neurology & neurosurgery ,Research Article - Abstract
Background Metabolic syndrome (Mets) is prevalent in the general population and has been reported to be an independent risk factor for cognitive impairment. This study aimed to investigate the association of Mets with the risk of cognitive impairment. Methods We studied 5854 participants from the Jidong community. Cognitive function was assessed by the Mini-Mental State of Examination (MMSE) scale. Mets was diagnosed according to the International Diabetes Federation criteria. We used logistic regression analysis to investigate the association of metabolic syndrome with the risk of cognitive impairment. Result Among the 5854 adults included in the study, the age mean (SD) of age was 44 (13.57) years, and 2916 (50.34%) were male. There was a higher (56.03%) cognitive impairment incidence rate among participants with Mets than among those without Mets. In addition, there was a significant association between Mets and cognitive impairment (OR: 2.39, 95% CI: 2.00–2.86, P P P P Conclusion Our study suggested that Mets was associated with cognitive impairment and that abdominal obesity and hypertension were associated with an increased risk of cognitive impairment.
- Published
- 2021