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Limonoids from the Fruits of Khaya ivorensis
- Source :
- Molecules, Molecules, Vol 19, Iss 3, Pp 3004-3011 (2014), Molecules; Volume 19; Issue 3; Pages: 3004-3011
- Publication Year :
- 2014
- Publisher :
- MDPI, 2014.
-
Abstract
- Two new limonoids, namely 14,15-didehydroruageanin A (1) and 3-O-methyl- butyrylseneganolide A (2), were isolated from the fruits of Khaya ivorensis along with six known limonoids: seneganolide A (3), 1,3-dideacetylkhivorin (4), 7-deacetylkhivorin (5), 3-deacetylkhivorin (6), 1-deacetylkhivorin (7), and 3-deacetyl-7-oxokhivorin (8). All the compounds were evaluated for their cytotoxicity against five tumor cell lines.
- Subjects :
- Limonins
Khaya ivorensis
Pharmaceutical Science
Tumor cells
Article
limonoids
14,15-didehydroruageanin A
Analytical Chemistry
lcsh:QD241-441
Inhibitory Concentration 50
lcsh:Organic chemistry
Cell Line, Tumor
Drug Discovery
Humans
Physical and Theoretical Chemistry
Meliaceae
Cytotoxicity
Nuclear Magnetic Resonance, Biomolecular
biology
Traditional medicine
Molecular Structure
Chemistry
Organic Chemistry
biology.organism_classification
Chemistry (miscellaneous)
Fruit
Molecular Medicine
3-O-methylbutyryl- seneganolide A
cytotoxicity
Subjects
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 19
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Molecules
- Accession number :
- edsair.doi.dedup.....5605795898efe3ddc48c23a5e30009d2