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Relationships between menstrual status and obesity phenotypes in women : a cross-sectional study in northern China
- Source :
- BMC Endocrine Disorders, BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-8 (2020)
- Publication Year :
- 2020
- Publisher :
- Research Square Platform LLC, 2020.
-
Abstract
- Background One of most important concerns of postmenopausal women is obesity. The relationships between menstruation status and obesity phenotypes are unclear. This study aimed to assess the associations between menstrual status and different obesity phenotypes in women. Methods In total, 5373 women aged ≥40 years were recruited from the Jidong and Kailuan communities. Basic information was collected via clinical examination, laboratory testing and standardized questionnaires. The women were stratified into the following three groups: menstrual period, menopausal transition period and postmenopausal period. General obesity was defined as a body mass index (BMI) of ≥28 kg/m2. Central obesity was defined as a waist-to-hip ratio (WHR) of > 0.85. Visceral obesity was defined as the presence of nonalcoholic fatty liver disease (NAFLD) and increased pericardial fat volume (PFV). Results The numbers of women in the menstrual, menopausal transition, and postmenopausal periods were 2807 (52.2%), 675 (12.6%) and 1891 (35.2%), respectively. The adjusted odds ratio (OR) and 95% confidence interval (CI) for central obesity among women in the menopausal transition and postmenopausal periods compared with women in the menstrual period were 0.99 (0.82–1.19) and 1.52 (1.26–1.84), respectively. The OR for NAFLD among postmenopausal women was 1.78 (1.44–2.20). The adjusted β-coefficient (standard error, SE) for PFV among postmenopausal women was 41.25 (7.49). The adjusted OR for general obesity among postmenopausal women was 1.01 (0.77–1.34). Conclusions This study demonstrated that menopause is an independent risk factor for central and visceral obesity but not general obesity.
- Subjects :
- Adult
medicine.medical_specialty
China
Cross-sectional study
Endocrinology, Diabetes and Metabolism
030204 cardiovascular system & hematology
lcsh:Diseases of the endocrine glands. Clinical endocrinology
Body Mass Index
Menstruation
03 medical and health sciences
0302 clinical medicine
Diabetes mellitus
medicine
Humans
Obesity
Risk factor
lcsh:RC648-665
030219 obstetrics & reproductive medicine
Obstetrics
business.industry
General Medicine
Odds ratio
Middle Aged
medicine.disease
Prognosis
Menopause
Phenotypes
Cross-Sectional Studies
Phenotype
Postmenopausal
Female
business
Body mass index
Research Article
Follow-Up Studies
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- BMC Endocrine Disorders, BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-8 (2020)
- Accession number :
- edsair.doi.dedup.....4d86b861fa013e178b36cdf88ed2822e