Search

Researchers from Shandong Jianzhu University in Jinan, People's Republic of China, have developed a discriminative atom-embedding relation dual network for the classification of Choroidal Neovascularization (CNV) in OCT images. CNV is an eye disease that can lead to vision loss, and accurate classification is crucial for treatment. The proposed method aims to address challenges in distinguishing between different CNV types and the limited availability of labeled data. Experimental results on private and public datasets have shown the effectiveness of this approach, which has been peer-reviewed. [Extracted from the article]

Researchers at Shandong University in Jinan, People's Republic of China, have developed a new method for accurately picking up microseismic signals in tunnels using kurtosis values and the Akachi information criterion (AIC). This method aims to improve efficiency and accuracy in identifying microseismic wave arrivals, particularly in situations with low signal-to-noise ratios. The study, supported by the National Key R & D Program of China and the National Natural Science Foundation of China, has been peer-reviewed and offers valuable insights into microseismic positioning techniques. [Extracted from the article]

Researchers at QILU University of Technology in Jinan, China, have developed a new method for synthesizing porous PtPb neural network-like nanowires for the electrooxidation of methanol with co-poisoning tolerance. The nanowires exhibit unique structural features that enhance their mass activity for methanol oxidation, surpassing that of other catalysts. This research, funded by various programs and institutions, has been peer-reviewed and published in the International Journal of Hydrogen Energy. For more information, readers can contact the lead author at QILU University of Technology in Jinan, China. [Extracted from the article]

Researchers from Shandong University in Jinan, People's Republic of China, have developed a method for detecting cervical spondylotic myelopathy (CSM) based on gait analysis and deterministic learning theory. By analyzing gait dynamics and using neural networks, they achieved an average classification accuracy of 94.44% to 95.56% in distinguishing CSM patients from healthy controls. This method shows promise for automatic CSM detection in clinical settings and has been peer-reviewed for accuracy and reliability. [Extracted from the article]

A recent study conducted at Shandong University in Jinan, People's Republic of China, focused on the development of potential inhibitors for Glycogen Synthase Kinase 3 beta (GSK-3 beta) as a target for anti-Alzheimer's disease drug development. The study synthesized novel thieno[3,2-c]pyrazol-3-amine derivatives and identified compound 54 as a potent GSK-3 beta inhibitor with neuroprotective effects in rat primary cortical neurons. Additionally, compound 54 showed anti-neuroinflammatory effects in astrocytes and microglia cells, and demonstrated anti-Alzheimer's disease activity in an AlCl3-induced zebrafish model. The research has been peer-reviewed and published in Bioorganic Chemistry. [Extracted from the article]

A study conducted at Shandong Normal University in Jinan, People's Republic of China, explored the impact of Benzo(a)pyrene (BaP) exposure during pregnancy on male mice offspring. The research found that gestational BaP exposure led to germ cell apoptosis in the testicular tissue of F1 male mice through histone modifications and increased oxidative stress levels. The study highlighted the detrimental effects of BaP on sperm quality and reproductive health, shedding light on the mechanisms underlying infertility caused by environmental endocrine-disrupting chemicals. This research was funded by the National Natural Science Foundation of China and the Key Laboratory of Assisted Reproduction, Ministry of Education. [Extracted from the article]

A study conducted at the University of Jinan in the People's Republic of China focused on developing a pH-responsive antibacterial material to combat biofilms caused by Gram-Positive Bacteria, specifically Staphylococcus aureus. The research introduced a copolymer micelle, PQACs(10)-co-PEGMA(10), which demonstrated effective antibacterial activity against Staphylococcus aureus biofilms. The micelles were found to prevent biofilm formation and eradicate existing biofilms, showing promise for reducing biofilm-related infections. The study was supported by the Natural Science Foundation of Shandong Province and has been peer-reviewed. [Extracted from the article]

A study conducted at Shandong University in Jinan, People's Republic of China, explored the impact of exposure to polystyrene microplastics (PS-MPs) on the immune system of male mice and their offspring during lactation. The research found that male mice exposed to PS-MPs showed increased spleen weight and elevated levels of certain immune cells, which were also observed in their F1 male offspring. However, these immune alterations were less pronounced in F1 female offspring and minimal in the F2 generation, indicating a pro-inflammatory state in the spleen that is not inherited across generations. This study highlights the potential effects of PS-MPs on immune status in mammals and their offspring. [Extracted from the article]

A recent study conducted at Shandong University in Jinan, People's Republic of China, focused on the modeling and verification of cortical bone drilling forces based on tissue structure heterogeneity. The research established a drilling force model for modified drills with thinned chisel edges, incorporating bone mineral density to predict axial thrust force changes during drilling. The study found that the modified drill design significantly reduced average thrust force and roughness of the hole wall compared to common drill bits, improving drilling performance. This peer-reviewed research provides valuable insights into optimizing cortical bone drilling processes and drill geometry. [Extracted from the article]

A recent study from the University of Jinan in China focused on the design and 3D printing of glass-ceramic/zirconia composite ceramics for dental applications. The research aimed to address the limitations of commonly used ceramic materials in dental prosthetic restorations by creating a novel composite ceramic with improved mechanical properties. The study found that a composite with 40 wt% YSZ fibers exhibited optimal performance, resulting in increased fracture toughness and reduced wear rates compared to pure glass-ceramic materials. This research offers a promising approach for developing high-performance, all-ceramic dental materials. [Extracted from the article]

Researchers at Shandong Normal University in Jinan, China, have developed a filter membrane-based colorimetric approach for point-of-care detection of biomarkers using CRISPR-Cas12a technology. This method allows for easy and accurate detection of disease biomarkers without the need for costly instruments, making it promising for use in resource-limited settings. The study has been peer-reviewed and offers a new strategy for accessible diagnostics in healthcare. [Extracted from the article]

Researchers from Shandong University in Jinan, People's Republic of China, have conducted a study on correcting the shape of deep-towed seismic arrays using floaters and a cone-shaped drogue. The study found that the floaters had a more significant effect than the drogue in correcting the array shape, resulting in improved hydrophone positioning and signal-to-noise ratio in seabed profiles. The research highlights the efficiency of numerical simulation in developing stabilization equipment for deep-towed multi-channel seismic arrays. This study was peer-reviewed and published in Ocean Engineering. [Extracted from the article]

A recent study from the University of Jinan in the People's Republic of China introduces a novel biosensor utilizing low excitation potential carbon quantum dots driven by magnetic metal-organic frameworks for sensitive immunoassays. The research focuses on the efficient emission of carbon dots to enable precise detection of low levels of neuron-specific enolase (NSE) in clinical research. This innovative approach offers a solution for the sensitive detection of biomarkers, showcasing a wide detection range and low detection limits for ECL and DPV methods. [Extracted from the article]

A new report from QILU University of Technology in Jinan, China discusses the topic of data and model poisoning backdoor attacks on wireless federated learning (WFL) and the defense mechanisms against them. WFL is a method of training a global deep learning model in wireless communication networks. The report provides a comprehensive survey of backdoor attacks and defense mechanisms, analyzing their targets, attack phases, and defense stages. The research compares existing attack methods and defense designs, highlighting open challenges and potential future research directions for the security and privacy of WFL. [Extracted from the article]

A study conducted by researchers at Qingdao University in Jinan, China, has found that inhalation of graphitic carbon nitride (g-CN) nanosheets can lead to the deposition of pulmonary surfactants in the lungs. The study also revealed that the doping of sulfur in graphitic carbon nitride reduced the hazardous effects on the respiratory system. These findings provide valuable insights into the potential respiratory hazards of graphitic carbon nitride and contribute to the assessment of its pulmonary toxicity. The research was supported by the National Natural Science Foundation of China and other funding sources. [Extracted from the article]

Researchers from QILU University of Technology in Jinan, China have conducted a study on the photochemistry and photophysics of metal-metal bonded dinuclear transition metal complexes (TMCs). These complexes play a crucial role in light-mediated processes and have been extensively studied due to their well-defined electronic and vibrational configurations. The study provides insights into the molecular design principles for optimizing the photophysical properties of these complexes and enhancing their practical applicability. The research was supported by various funding sources and has been peer-reviewed. [Extracted from the article]

A recent study conducted by researchers at Shandong University of Traditional Chinese Medicine in Jinan, People's Republic of China, explores the challenges of extracting and separating active components from traditional Chinese medicine. The researchers developed a composite material using a Zr-based metal-organic framework that demonstrated significant selectivity in capturing and separating targeted analytes. The approach showed promising results in terms of recovery, repeatability, and stability. This research provides valuable insights and a versatile methodology for extracting active ingredients from complex matrices. [Extracted from the article]

A recent study conducted by researchers at Shandong University in Jinan, China, examined the hemodynamic behavior of umbrella-shaped inferior vena cava filters (IVCFs) using computational fluid dynamics. The study found that all five IVCFs analyzed exhibited prothrombotic stagnation zones downstream of the filter head, which could potentially lead to life-threatening conditions such as IVC lesions, filter rupture, and displacement. The researchers also observed that alterations in the morphology of the filter wires significantly impacted the flow resistance of the filter and the distribution pattern of wall shear stress on the IVC. This research provides valuable insights into the hemodynamic characteristics of umbrella-shaped IVCFs and highlights the importance of considering these factors in clinical practice. [Extracted from the article]

A systematic review conducted by researchers at Shandong University in Jinan, China, evaluated the quality and applicability of clinical practice guidelines for the rehabilitation of knee osteoarthritis (OA). The study analyzed 24 guidelines published between 2008 and 2022 and used the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument for evaluation. The review found that the overall quality of the guidelines was good, but the applicability was slightly poor. The study suggests the need for improvement in factors that promote and hinder guideline application, as well as recommendations, tools, and resources for developing relevant guidelines. [Extracted from the article]

A recent study conducted by researchers at QILU University of Technology in Jinan, China, investigated the hepatoxic effects of borneol using zebrafish. Borneol is commonly used in food and cosmetics without much safety evaluation. The study found that high doses of borneol caused liver size decrease or lateral lobe absence in zebrafish. It also disrupted hepatic protein metabolism and lipid metabolism, leading to lipid accumulation and hepatic injury. The study provides a better understanding of borneol hepatoxicity and can contribute to the safe use of this compound. [Extracted from the article]

A study conducted at the University of Jinan in China has found that concave single-atom Co catalysts with densely edge-hosted active sites can act as highly efficient oxidase mimics. These catalysts, known as H-Co SACs, displayed 3.1 times higher catalytic activity compared to traditional intact Co single-atom catalysts. The researchers also applied H-Co SACs to the colorimetric enzyme-linked immunosorbent assay (ELISA) of neuron specific enolase (NSE) and achieved a detection limit of 5.19 pg/mL, outperforming both intact Co single-atom catalysts and standard commercial ELISA kits. This study highlights the significance of geometric structure and active site density in improving the catalytic efficiency of nanozymes and expands their potential clinical applications. [Extracted from the article]

Researchers at Shandong University in Jinan, China have developed a semi-interpenetrating polymer network (semi-IPN) anion exchange membrane (AEM) for acid recovery through diffusion dialysis. The AEMs demonstrated excellent dimensional stability, high oxidation stability, good acid dialysis coefficient, and high separation factor. The semi-IPNs also exhibited promising potential with good water uptake, swelling ratio, thermal stability, and oxidation stability. This research provides a potential solution for acid recovery from acidic waste that is economically feasible and environmentally friendly. [Extracted from the article]

A study conducted by researchers at Shandong Normal University in Jinan, China, has developed a novel green solvent called surfactant-free microemulsion (SFME) that improves the solubilization, stability, dialysis performance, and antioxidant properties of the flavonol compound quercetin. The researchers found that the solubility of quercetin in SFME was much higher than in water or ethanol, and that SFME also improved the light, heat, storage stability, and antioxidant properties of quercetin. The study suggests that SFME could have important applications in the extraction and separation of natural foods. The research has been peer-reviewed and published in the Journal of Molecular Liquids. [Extracted from the article]

A study conducted by researchers at Shandong University in Jinan, People's Republic of China, has developed an implantable zinc ion battery (ZIB) that can power electronic devices and has potential applications in medicine. The ZIB demonstrated high capacity and stability, as well as good biocompatibility and degradability. The battery's catabolites were found to induce anti-inflammatory properties and promote osteogenic differentiation of bone marrow mesenchymal stem cells. The researchers also designed a wireless energy transmission module for real-time charging of the ZIB. The study concludes that the ZIB shows promise as a power source for implantable medical electronic devices and as a functional material for accelerating bone repair. [Extracted from the article]

Researchers at Shandong University in Jinan, China have developed a self-cleaning flex-occlusometer for dental health monitoring. This device uses superhydrophobic capacitive sensors to measure and track occlusal forces, which are important for diagnosing dental issues and evaluating the impact of lifestyle on oral health. The flex-occlusometer has a wireless transmission module and smart interface, allowing for real-time data visualization and personalized dental care. It is resistant to mechanical abrasion, chemical corrosion, and pollutant residues. The research was supported by the National Natural Science Foundation of China and has been peer-reviewed. [Extracted from the article]

A report from investigators at Shandong Normal University in Jinan, China, discusses the findings of a study on air quality in a polluted city in North China. The study used a multi-channel particle size sensor and statistical models to analyze the particle size distribution and its influencing factors from winter 2021 to autumn 2022. The results showed that heavy pollution episodes were mainly caused by fine particles in winter and coarse particles in spring. The study also found correlations between particle concentrations and meteorological and air pollutant factors. The researchers suggest that emission controls on certain pollutants and regional joint pollution prevention are preferred to reduce urban air pollution in the future. [Extracted from the article]

A recent report from QILU University of Technology in Jinan, China, discusses the use of nanocrystals to improve the properties of cellulose acetate (CA) dialysis membranes. The researchers used a blending modification technique to enhance the hemocompatibility of the CA membrane and give it endotoxin scavenging and antibacterial capabilities. The modified CA membrane showed good blood compatibility, noncytotoxicity, and excellent endotoxin adsorption capacity. The researchers believe that this modified membrane has potential applications in hemodialysis and blood purification. [Extracted from the article]

Researchers at QILU University of Technology in Jinan, China have developed a simple and template-free method for synthesizing porous nanowires (PNWs) made of platinum and silver (PtAgx PNWs). These PNWs have high surface areas, abundant active sites, and are highly durable against aggregation. The PtAg PNWs demonstrated superior performance in methanol oxidation reaction (MOR) compared to other catalysts, with a higher mass activity and CO-poisoning tolerance. Density functional theory (DFT) simulations confirmed the effectiveness of PtAg PNWs in MOR. This study opens up possibilities for the synthesis of Pt-based PNWs alloys with various metals for MOR applications. [Extracted from the article]

Researchers at the University of Jinan in Jinan, People's Republic of China, have developed a pressure-responsive self-lubricating ice-phobic organogel with high mechanical strength. The organogels, made from fluorinated polynorbornene networks, exhibited excellent stability and durability, even under harsh conditions. They also demonstrated a reversible pressure-responsive effect, where the paraffin in the gels could migrate to form a self-lubricating layer on the surface under external force. The mechanical, anti-icing, and antifrosting properties of the organogels could be adjusted by varying the paraffin content. This study offers a convenient approach to developing smart anti-icing materials with high mechanical durability. [Extracted from the article]

A recent report from Shandong University in Jinan, China, discusses the development of linearly polarized multiwavelength lasers using solution-processed quantum dots. These lasers have the potential to be used in applications such as optical computing, optical storage, and optical sensing. By adjusting the structural polarization and energy transfer in quantum dots, the researchers were able to achieve linearly polarized broadband emission and multiwavelength lasers in the visible and near-infrared wavelength ranges. These lasers offer advantages in terms of miniaturization, low power consumption, and adaptability for integration, making them a promising light source for future photonic integrated circuits. [Extracted from the article]

A recent study conducted at the University of Jinan in China explores the use of MXenes in bacterial detection and eradication. The study highlights the challenges faced by traditional strategies in bacterial management and detection, such as sensitivity constraints and antibiotic resistance. The researchers examine the synthesis techniques and structural traits of MXenes, as well as their potential in bacterial detection sensors and antibacterial applications. The study concludes that MXene-based research has made substantial advancements in bacterial identification and eradication. [Extracted from the article]

A study conducted by the Shandong Academy of Occupational Health and Occupational Medicine in Jinan, China, has developed a portable kit for the rapid and accurate detection of paraquat (PQ) in human urine and gastric juice. The kit utilizes the surface-enhanced Raman scattering (SERS) technique and gold-silver core-shell nanoparticles as the substrate. The detection process takes only one minute and does not require any pretreatment procedures. The researchers believe that this point-of-care testing (POCT) assay has significant potential as an innovative alternative for poisoning detection applications. [Extracted from the article]

A study conducted by researchers at QILU University of Technology in Jinan, People's Republic of China, explores the use of a flexible dual Fe-based catalyst to remove H2S in a discontinuous removal process. The researchers found that a metal-organic framework (MOF) incorporating 30 wt% deep eutectic solvent (DES) exhibited the best H2S removal performance at 180 degrees C. The process of desulfurization involves catalytic oxidation and adsorption, with elemental sulfur being the predominant product. The study suggests that both elemental sulfur and DES can induce the flexible deformation of the MOF to prevent catalyst passivation. [Extracted from the article]

A study conducted by Shandong University in Jinan, People's Republic of China, aimed to develop and validate a new scale to measure health problem prevention and control strategies used by medical rescuers fighting epidemics. The study involved qualitative research methods, focus group discussions, and expert panel reviews to generate items for the scale. The final scale consisted of three subscales with a total of 47 items. The research concluded that the scale has excellent validity and reliability and can be used to measure the health problem prevention and control strategies of medical rescuers fighting epidemics. [Extracted from the article]

A study conducted by researchers from Shandong University in Jinan, China, explores the use of modified polyurea coated helmets to mitigate the effects of shock waves on the brain. The study focuses on the protection against traumatic brain injury caused by explosive blasts, which is a leading cause of death in military conflicts. The researchers designed a new type of shock wave protection helmet by adding SiO2 nanoparticles to the polyurea material. The experiments showed that the addition of SiO2 nanoparticles improved the shock mitigation properties of the helmet, reducing peak overpressure and acceleration of the shock wave. The study concludes that the new material provides effective protection against shock waves. [Extracted from the article]

Researchers from the University of Jinan in China have developed a novel multifunctional hemostatic material for wounds. The material, based on carboxymethyl chitosan (CMC), demonstrated excellent hemostatic properties in in vivo and in vitro experiments. It also exhibited antibacterial and anti-adhesion properties, which could help prevent wound infections. The material's biocompatibility was confirmed through hemolysis and cytotoxicity tests. This research holds promising potential for rapid hemostasis and wound infection prevention. [Extracted from the article]

Researchers from Shandong University in Jinan, China have discovered that adding vitamin C to aqueous zinc-ion batteries (AZIBs) can improve their performance. The vitamin C molecule adjusts the d band center of the zinc substrate, which reduces the hydrogen evolution reaction (HER) and improves the solvation structure of zinc ions. This leads to a longer cycle performance, higher Coulombic efficiency, and increased rate capability in the batteries. The findings shed light on the mechanism behind electrolyte additives and could lead to further studies in this area. [Extracted from the article]

A recent report from QILU University of Technology in Jinan, People's Republic of China, discusses the solubility, thermodynamic parameters, and dissolution properties of 17-alpha hydroxyprogesterone (OHP) in 13 pure solvents. The study found that the solubility of OHP increased with increasing temperature. Various models were used to correlate the experimental solubility data, with the Yaws model providing the best results. The thermodynamic analysis showed that the mixing process was spontaneous, and the dissolution of OHP in the selected solvents was an endothermic reaction with increasing entropy. Further details of the research can be found in the journal article published in ACS Omega. [Extracted from the article]

A recent study conducted by researchers at Shandong University in Jinan, China, explores the use of audio and video-based biomarkers for the automatic recognition of depression. The study highlights the limitations of current depression detection methods and the potential of deep learning technology to capture non-biological markers of depression. The researchers provide a review of commonly used datasets, identify deficiencies in existing research, and suggest future directions for development. This research has been peer-reviewed and published in the World Journal of Psychiatry. [Extracted from the article]

A recent report from the University of Jinan in China discusses the prevention of ferroptosis, a form of regulated cell death, in vascular endothelial cells (VECs) induced by high glucose (HG). The study synthesized and evaluated novel ferrostatin derivatives to prevent HG-induced VEC ferroptosis. Compound 12 was identified as a promising lead compound for treating ferroptosis-associated vascular diseases. Further optimization is needed due to its undesirable microsomal stability. This research provides valuable insights into potential treatments for diseases related to ferroptosis. [Extracted from the article]

Researchers at Shandong Youth University of Political Science in Jinan, China have developed an artificial intelligence (AI) system for analyzing cytopathology images in medical decision-making. The system uses high-resolution medical representation learning to segment pathology images and quantify statistical results. The researchers designed two models, HRMED_T and HRMED_S, for cell nucleus segmentation, achieving accurate results with an Intersection over Union (IoU) of 0.756 and 0.710, respectively. This AI system shows promise in improving the efficiency and objectivity of visual screening techniques in pathology. [Extracted from the article]

A study conducted at the Shandong Provincial Hospital for Skin Diseases in Jinan, China, examined the characteristics and treatment outcomes of 35 patients with cutaneous Mycobacterium marinum infections. The study found that 71.4% of the patients had lesions with sporotrichoid patterns. The duration of treatment and the presence of sporotrichoid lesions were associated with longer treatment times, although the differences were not statistically significant. The study also investigated the immune response induced by M. marinum infection and found upregulated expression levels of certain cytokines in patient specimens. Further research is needed to explore these findings. [Extracted from the article]

Researchers at Shandong University in Jinan, China have developed a metal-phenolic nanocoating for bone implants that enhances osseointegration through early immunomodulation. The nanocoating, made of tannic acid and Sr2+, provides a bioactive interface that promotes the adhesion and recruitment of bone marrow mesenchymal stem cells and polarizes macrophages towards an M2 phenotype. The nanocoating also accelerates osteogenic differentiation and enhances osseointegration around the implant. This research suggests that the metal-phenolic nanocoating is a promising strategy for achieving better and faster osseointegration of bone implants, with potential for future clinical applications. [Extracted from the article]

A recent study conducted at the University of Jinan in China has developed a highly efficient gas sensor for detecting formaldehyde (HCHO) at low concentrations. The sensor, composed of nanoflower In2O3/CuO self-assembly, demonstrated excellent performance with a large response value and shorter response and recovery times compared to other sensors. The researchers attribute these properties to the unique hierarchical structure of the sensor. This research opens up new possibilities for detecting trace amounts of HCHO gas. [Extracted from the article]

A meta-analysis conducted by researchers at Jinan Third People's Hospital in China has found a significant association between circulating betatrophin levels and type 2 diabetes mellitus (T2DM). The study analyzed relevant literature published up to June 2023 and compared betatrophin levels between individuals with T2DM and healthy controls. The meta-analysis revealed higher betatrophin levels in individuals with T2DM, particularly among Asian individuals. The findings suggest that betatrophin may serve as a potential diagnostic biomarker for T2DM. This research has been peer-reviewed and published in Minerva Endocrinology. [Extracted from the article]

Researchers at QILU University of Technology in Jinan, China have developed a cancellous bone-like polyurethane foam with excellent properties for ultra-high energy absorption. The foam was created using a planetary centrifugal mixing method, resulting in a unique microstructure with thick walls and small pores. The foam demonstrated high compressive strength, energy absorption capacity, antistatic property, low thermal conductivity, and fast heating responsiveness. This cost-effective method offers a simple way to obtain high energy absorption materials with excellent comprehensive properties. The research has been peer-reviewed and published in ACS Applied Polymer Materials. [Extracted from the article]

A recent study conducted by researchers at the University of Jinan in China has developed a highly sensitive electrochemiluminescence immunosensor for the detection of CA19-9, a biomarker associated with certain cancers. The sensor utilizes ternary compound CdSSe nanoparticles as an emitter, with Cu2S and gold-doped diindium trioxide (Au-In2O3) nanocubes acting as coreaction accelerators to achieve a double-amplification strategy. The immunosensor demonstrated a wide linear range and a low detection limit, making it a promising tool for sensitive detection of CA19-9. This research was funded by the National Natural Science Foundation of China and the Special Foundation for Taishan Scholar Professorship of Shandong Province. [Extracted from the article]