1. Studying the Sensitivity of Graphene for Biosensor Applications.
- Author
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Usikov, A. S., Lebedev, S. P., Roenkov, A. D., Barash, I. S., Novikov, S. V., Puzyk, M. V., Zubov, A. V., Makarov, Yu. N., and Lebedev, A. A.
- Subjects
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GRAPHENE , *SALINE solutions , *FLUORESCEIN , *MAGNITUDE (Mathematics) , *RESISTANCE to change - Abstract
We have studied the response of graphene-film-based chips on SiC substrates (the relative change in the chip resistance) to coming into contact with fluorescein (C20H12O5) in a wide range of its concentrations in a phosphate-buffered saline solution: from 1 × 10–3 to 1 × 104 ng/mL (seven orders of magnitude). Fluorescein detection seems to be a simple and cheap model experiment to study the sensory ability of graphene in the way of biochips manufacturing. It has been shown that chips with wide terraces on a surface with a step width of about 1000 nm and heights of up to 5 nm made it possible to construct the calibration dependences of chip response on fluorescein concentration. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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