41 results on '"Perkins, Darren J."'
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2. Autocrine–paracrine prostaglandin E2 signaling restricts TLR4 internalization and TRIF signaling
3. CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance
4. INFLAMMATION: Species-specific TLR signalling — insight into human disease
5. Contributors
6. Signaling Mechanisms Regulating Innate Immune Responses
7. Space and time: New considerations about the relationship between Toll-like receptors (TLRs) and type I interferons (IFNs)
8. Microbiota-Derived Metabolites, Indole-3-aldehyde and Indole-3-acetic Acid, Differentially Modulate Innate Cytokines and Stromal Remodeling Processes Associated with Autoimmune Arthritis
9. cAMP levels regulate macrophage alternative activation marker expression
10. A mouse model of human TLR4 D299G/T399I SNPs reveals mechanisms of altered LPS and pathogen responses
11. sj-pdf-1-ini-10.1177_1753425920975082 - Supplemental material for cAMP levels regulate macrophage alternative activation marker expression
12. Dissociation of TRIF bias and adjuvanticity
13. Bordetella pertussis adenylate cyclase toxin (ACT) induces cyclooxygenase-2 (COX-2) in murine macrophages and is facilitated by ACT interaction with CD11b/CD18 (Mac-1)
14. cAMP levels regulate macrophage alternative activation marker expression.
15. Influenza “Trains” the Host for Enhanced Susceptibility to Secondary Bacterial Infection
16. Improved Tolerability of a Salmonella enterica Serovar Typhimurium Live-Attenuated Vaccine Strain Achieved by Balancing Inflammatory Potential with Immunogenicity
17. Type I interferon Licenses Enhanced Innate Recognition and Transcriptional Responses to Franciscella tularensis LVS
18. AMP-activated Kinase (AMPK) Promotes Innate Immunity and Antiviral Defense through Modulation of Stimulator of Interferon Genes (STING) Signaling
19. The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation
20. Epigenetic Mechanisms Governing Innate Inflammatory Responses
21. The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation
22. Type I interferon licenses enhanced innate recognition and transcriptional responses to Franciscella tularensis live vaccine strain
23. Species-specific TLR signalling — insight into human disease
24. Salmonella Typhimurium Co-Opts the Host Type I IFN System To Restrict Macrophage Innate Immune Transcriptional Responses Selectively
25. Autocrine–paracrine prostaglandin E2signaling restricts TLR4 internalization and TRIF signaling
26. Invasive Salmonella Typhimurium ST313 with Naturally Attenuated Flagellin Elicits Reduced Inflammation and Replicates within Macrophages
27. The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation.
28. Reprogramming of Murine Macrophages through TLR2 Confers Viral Resistance via TRAF3-Mediated, Enhanced Interferon Production
29. Dissociation of Endotoxin Tolerance and Differentiation of Alternatively Activated Macrophages
30. Complete Dependence on IRAK4 Kinase Activity in TLR2, but Not TLR4, Signaling Pathways Underlies Decreased Cytokine Production and Increased Susceptibility to Streptococcus pneumoniae Infection in IRAK4 Kinase–Inactive Mice
31. 5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential
32. Transcriptional Regulation of Murine IL-33 by TLR and Non-TLR Agonists
33. A Toll-Like Receptor-Responsive Kinase, Protein Kinase R, Is Inactivated in Endotoxin Tolerance through Differential K63/K48 Ubiquitination
34. TLR4/MyD88/PI3K interactions regulate TLR4 signaling
35. Defects in Translational Regulation Mediated by the α Subunit of Eukaryotic Initiation Factor 2 Inhibit Antiviral Activity and Facilitate the Malignant Transformation of Human Fibroblasts
36. Characterization of Two Evolutionarily Conserved, Alternatively Spliced Nuclear Phosphoproteins, NFAR-1 and -2, That Function in mRNA Processing and Interact with the Double-stranded RNA-dependent Protein Kinase, PKR
37. Type I interferon licenses enhanced innate recognition and transcriptional responses to Franciscella tularensislive vaccine strain
38. A mouse model of human TLR4 D299G/T399I SNPs reveals mechanisms of altered LPS and pathogen responses.
39. Improved Tolerability of a Salmonella entericaSerovar Typhimurium Live-Attenuated Vaccine Strain Achieved by Balancing Inflammatory Potential with Immunogenicity
40. Quantitation of TLR4 Internalization in Response to LPS in Thioglycollate Elicited Peritoneal mouse Macrophages by Flow Cytometry.
41. Defects in translational regulation mediated by the alpha subunit of eukaryotic initiation factor 2 inhibit antiviral activity and facilitate the malignant transformation of human fibroblasts.
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