1. Prognosis of Vascular Access in Haemodialysis Patients with Autosomal Dominant Polycystic Kidney Disease
- Author
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Shuo Ming Ou, Ko Wen Yu, Yung Tai Chen, Chih Ching Lin, Chun Fan Chen, Tsung Lun Lee, Ann Charis Tan, Chia Hao Chan, and Fan Yu Chen
- Subjects
Adult ,Male ,medicine.medical_specialty ,Time Factors ,030232 urology & nephrology ,Autosomal dominant polycystic kidney disease ,Urology ,Vascular access ,Taiwan ,Arteriovenous fistula ,lcsh:Medicine ,030204 cardiovascular system & hematology ,urologic and male genital diseases ,Article ,03 medical and health sciences ,0302 clinical medicine ,Primary outcome ,Arteriovenous Shunt, Surgical ,Postoperative Complications ,Renal Dialysis ,Risk Factors ,Polycystic kidney disease ,medicine ,Humans ,In patient ,cardiovascular diseases ,lcsh:Science ,Vascular Patency ,Aged ,Retrospective Studies ,Multidisciplinary ,business.industry ,Incidence (epidemiology) ,Incidence ,lcsh:R ,Retrospective cohort study ,Middle Aged ,medicine.disease ,Polycystic Kidney, Autosomal Dominant ,Prognosis ,Haemodialysis ,Propensity score matching ,Kidney Failure, Chronic ,Female ,lcsh:Q ,business ,Follow-Up Studies - Abstract
Vascular diseases are commonly observed in patients with autosomal dominant polycystic kidney disease (ADPKD). We aim to investigate the differences in the risk for arteriovenous fistula or graft (AVF/AVG) dysfunction in haemodialysis (HD) patients with and without ADPKD. 557 ADPKD and 1671 non-ADPKD patients were enrolled in the study after propensity score matching. The primary outcome measure is the incidence rate of AVF/AVG dysfunction. The incidence rates and risks of AVF/AVG dysfunction (per 100 person-years) for ADPKD and non-ADPKD patients were (1) 38.83 and 48.99 [SHR = 0.79, P = 0.137], respectively, for within 90 days, (2) 45.85 and 51.31 [SHR = 0.90, P = 0.300], respectively, for within 180 days, (3) 44.42 and 41.40 [SHR = 1.08, P = 0.361], respectively, for within the first year, (4) 27.38 and 24.69 [SHR = 1.09, P = 0.168], respectively, for within 5 years, (5) 17.35 and 13.80 [SHR = 1.19, P = 0.045], respectively, for between the 1st and 10th year, and (6) 25.40 and 21.22 [SHR = 1.14, P = 0.031], respectively, for all periods. ADPKD patients had lower incidence rates of AVF/AVG dysfunction within the first 180 days than non-ADPKD patients, but presented a higher incidence rate after 1 year of AVF/AVG creation and onwards.
- Published
- 2020