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Long-term prognosis of vascular access in hemodialysis patients with systemic lupus erythematosus: a retrospective cohort study
- Source :
- Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021), Scientific Reports
- Publication Year :
- 2020
-
Abstract
- Patients with systemic lupus erythematosus (SLE) have a higher risk of vascular complications. This retrospective cohort study aimed to analyze the differences in the risk of arteriovenous fistula or graft (AVF/AVG) dysfunction in hemodialysis patients with and without SLE from Taiwan’s National Health Insurance Database over a 10-year period. AVF/AVG dysfunction is defined as the occurrence of the first episode of intervention after vascular access creation. A total of 1366 HD patients with SLE had higher incidence rates of AVF/AVG dysfunction than 4098 non-SLE HD patients in the following 4 periods: (1) after 1 year (incidence rates = 15.21% and 13.01%, respectively; subdistribution hazard ratio (SHR) = 1.16; P = 0.007), (2) 1st-to-10th-year period (15.36% and 13.25%; SHR = 1.16; P = 0.007), (3) 5th-to-10th-year period (11.91% and 8.1%; SHR = 1.42; P = 0.003), and (4) overall period (23.53% and 21.66%; SHR = 1.09; P = 0.027). In conclusion, there were significantly higher incidence rates of AVF/AVG dysfunction in SLE patients during the long-term follow-up period. Vascular access function should be monitored regularly by clinical examinations, especially after 1 year and during 5 to 10 years, to improve AVF/AVG patency and dialysis adequacy in SLE patients undergoing maintenance hemodialysis.
- Subjects :
- Male
medicine.medical_specialty
medicine.medical_treatment
Science
Vascular access
Arteriovenous fistula
030204 cardiovascular system & hematology
Risk Assessment
Article
End stage renal disease
End-stage renal disease
03 medical and health sciences
Blood Vessel Prosthesis Implantation
Systemic lupus erythematosus
0302 clinical medicine
Arteriovenous Shunt, Surgical
Renal Dialysis
Risk Factors
Internal medicine
medicine
Humans
Lupus Erythematosus, Systemic
cardiovascular diseases
Vascular Diseases
skin and connective tissue diseases
030203 arthritis & rheumatology
First episode
Dialysis adequacy
Multidisciplinary
business.industry
Incidence (epidemiology)
Graft Occlusion, Vascular
Retrospective cohort study
Middle Aged
medicine.disease
Prognosis
Haemodialysis
Treatment Outcome
Arteriovenous Fistula
Medicine
Kidney Failure, Chronic
Female
Hemodialysis
business
Subjects
Details
- ISSN :
- 20452322
- Volume :
- 11
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific reports
- Accession number :
- edsair.doi.dedup.....2e4e18ec0e3609d994365069eeb00928