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A recent study conducted by researchers at the University of Helsinki focused on hemorrhagic fever with renal syndrome caused by Puumala orthohantavirus. The study found that levels of circulating mucosal-like IgA, a type of antibody, increased with the severity of acute kidney injury in patients. These findings suggest that excessive levels of mucosal-like IgA could potentially serve as a biomarker for disease progression in hemorrhagic fever with renal syndrome. The research provides valuable insights into the immune response to this viral infection and its impact on disease severity. [Extracted from the article]

A recent report discusses research on hantavirus pulmonary syndrome (HPS), an emerging disease caused by the rodent-borne virus genus Orthohantavirus. The study monitored rodent abundance in three sites in northwestern Argentina and found a synchronous rise in rodent abundance that anticipated an HPS outbreak in 2023. The researchers also identified a positive relationship between HPS cases and rodent abundance, as well as rainfall. The findings provide a framework for the planning and implementation of public health prevention campaigns based on climatology and rodent monitoring. HPS is a disease of public health concern due to its high mortality rate, lack of specific therapeutic treatment, and absence of a vaccine. [Extracted from the article]

A new report from Xinxiang Medical University in Henan, China, explores the effects of weather conditions on Hemorrhagic Fever with Renal Syndrome (HFRS) in both the long and short term. The study found that HFRS exhibited a declining trend from 2004 to 2019 and had a dual seasonal pattern, with peaks in June and October-December. The research identified long-term asymmetric effects of rainfall, wind velocity, and air pressure on HFRS, as well as short-term asymmetric impacts of relative humidity, rainfall, and air pressure. The study concludes that the NARDL model, which incorporates various weather parameters, is valuable for predicting HFRS epidemics and guiding prevention and control strategies. [Extracted from the article]

A recent preprint study examined the immune response in patients with acute Puumala orthohantavirus infection, which causes hemorrhagic fever with renal syndrome (HFRS). The study found that patients with more severe kidney injury had higher levels of circulating virus-specific and secretory IgA, a type of antibody. Additionally, the study found that excessive activation of the mucosal immune system may contribute to the progression of HFRS. This research provides insights into the immune response during HFRS and suggests that a balance in mucosal immune activation is important for infection clearance. However, it is important to note that this study has not yet undergone peer review. [Extracted from the article]

A recent report from the University of Helsinki discusses research on hemorrhagic fever with renal syndrome caused by the Puumala orthohantavirus. The study focuses on the role of neutrophils, a type of immune cell, in the disease. The researchers found that specific subsets of neutrophils were increased in patients with the disease, and these subsets were associated with thrombocytopenia, a condition characterized by low platelet levels. The study suggests that maturing neutrophils may play a role in the development of the disease. The findings also indicate that the response of neutrophils may differ depending on the virus causing the infection. [Extracted from the article]

A study conducted by Shandong University in China has found that meteorological factors can drive the transmission of Hemorrhagic Fever with Renal Syndrome (HFRS), a serious disease caused by the Hantavirus and transmitted by rodents. The study used a technique called Empirical Dynamic Modeling (EDM) to analyze the relationship between meteorological factors and HFRS outbreaks in Weifang City from 2011 to 2020. The results showed that temperature, humidity, precipitation, and wind speed can influence the occurrence and spread of HFRS, with an increase in incidence occurring 4-6 months after changes in meteorological conditions. The findings highlight the need for timely public health measures to mitigate the impact of climate change on the spread of HFRS. [Extracted from the article]

A new study conducted by researchers at the Shandong Center for Disease Control and Prevention in China focuses on the transmission of hemorrhagic fever with renal syndrome (HFRS) in Shandong Province. The study analyzes the spatiotemporal drivers and incidence heterogeneity of HFRS transmission in the region. The research found that the autoregressive component plays a significant role in the transmission of HFRS, and suggests that targeted preventive measures should be implemented based on the predominant component influencing the epidemic. This study provides valuable insights for public health officials and researchers studying HFRS in China. [Extracted from the article]

A recent study conducted at Split University Hospital in Croatia analyzed the long-term effects of hemorrhagic fever with renal syndrome (HFRS) on patients. The researchers found that 14 years after contracting the disease, convalescent HFRS patients exhibited higher levels of certain markers associated with endothelial dysfunction, inflammation, and renal dysfunction. However, the study also revealed that most endothelium dysfunction markers were not significantly different between post-HFRS patients and healthy individuals. These findings suggest that convalescent HFRS patients may experience mild chronic inflammation and renal dysfunction. [Extracted from the article]

A study conducted by researchers at the First Affiliated Hospital of Xinxiang Medical University in Shandong, China, has examined the impact of meteorological factors on hemorrhagic fever with renal syndrome (HFRS). The study found that HFRS exhibited a declining trend between 2004 and 2019, with a bimodal seasonality. The research identified both long-term and short-term asymmetric effects of meteorological factors on HFRS, including precipitation, sunshine hours, wind velocity, and relative humidity. The study suggests that incorporating meteorological factors into early warning systems can help mitigate the impact of HFRS. [Extracted from the article]

A recent study conducted at the University Hospital for Infectious Diseases in Zagreb, Croatia, has found that patients with hemorrhagic fever with renal syndrome (HFRS) have increased levels of inhibitory co-receptors TIM-3, LAG-3, and PD-1 in their serum. These proteins are believed to play a role in regulating the immune response and disease progression. The study used multiplex immunoassay to measure the levels of these proteins and found that higher levels were associated with certain clinical parameters such as creatinine, urea, lactate dehydrogenase concentrations, and platelet count. This research provides valuable insights into the pathogenesis of HFRS and may contribute to the development of new treatment strategies. [Extracted from the article]

A case study from the University of South China has provided new data on Hemorrhagic Fever With Renal Syndrome (HFRS). The study describes a case of a 36-year-old male with elevated ferritin, vitamin B12, and folic acid deficiency during the early onset phase of HFRS. Abnormal serum levels of ferritin, vitamin B12, and folic acid served as early indicators of renal dysfunction in patients with HFRS. The findings suggest that these biomarkers have the potential to play a predictive role in the diagnosis and treatment of the disease. [Extracted from the article]

Researchers from the Kazan Research Institute of Epidemiology and Microbiology have conducted a study on the epidemiological situation of Hantavirus infections, specifically focusing on hemorrhagic fever with renal syndrome (HFRS). The study analyzed the incidence of HFRS in the Russian Federation in 2023 and made a forecast for 2024. In 2023, there were 5,093 cases of HFRS in Russia, with a mortality rate of 0.49%. The study revealed a decrease in the incidence of HFRS compared to the previous year, but highlighted a continuing tense situation in the country. The research also predicted a high risk of complications in certain regions of Russia. The study concluded that sporadic cases of the disease may occur in the Southern Federal District, but the situation is not expected to worsen in the North-Caucasian and Siberian Federal Districts in 2024. [Extracted from the article]

A report from Southeast University in Nanjing, China discusses the detection methods for Seoul virus, a causative pathogen of hemorrhagic fever with renal syndrome (HFRS). The study utilized quantitative real-time PCR (qRT-PCR), metagenomic next-generation sequencing (mNGS), and immunological assays to identify the pathogen causing HFRS. Each method has its own advantages and disadvantages, and the optimal selection depends on laboratory conditions and clinical requirements. This research provides valuable information for accurately diagnosing and treating HFRS caused by Seoul virus. [Extracted from the article]

A study conducted by researchers at Ningbo University in China explores the epidemiology of hemorrhagic fever with renal syndrome (HFRS) and the dynamics of hantavirus hosts in Zhejiang Province. The study found that the incidence of HFRS has been decreasing over time, with cases distributed throughout the province except for Shengsi County. The epidemic of HFRS in Zhejiang Province has two seasonal peaks in winter and summer, and there has been an increase in the age of the affected population. The study also identified the species of rodents that carry the hantavirus, with striped field mice and brown rats being the most common carriers. [Extracted from the article]

A recent study conducted at the University Hospital for Infectious Diseases "Dr. Fran Mihaljevic" in Zagreb, Croatia, has reported on a rare case of acute respiratory distress syndrome (ARDS) caused by the Puumala orthohantavirus (PUUV). This is the first documented case of PUUV-associated ARDS in Southeast Europe. The patient, a 23-year-old male, presented with fever, headache, abdominal pain, and sudden onset of ARDS. Treatment involved high-flow nasal cannula oxygen therapy and glucocorticoids, resulting in a full recovery. The study highlights the importance of considering hantavirus pulmonary syndrome (HPS) in the differential diagnosis of ARDS, even in areas where hemorrhagic fever with renal syndrome (HFRS) is the dominant form of hantavirus infection. [Extracted from the article]

A recent study conducted by researchers at the Fourth Military Medical University in Shaanxi, China, explored the role of inflammatory monocytes (iMOs) in hemorrhagic fever with renal syndrome (HFRS), a severe illness caused by Hantaan virus (HTNV) infection. The study found that the proportion of CD226- iMOs in the acute phase of HFRS was significantly higher than in the convalescent phase and normal controls. Additionally, CD226- iMOs expressed lower levels of certain proteins involved in immune response compared to CD226+ iMOs. The researchers suggest that the expansion of CD226- iMOs and the decrease in CD226 expression may contribute to immune escape of HTNV and worsen clinical symptoms. [Extracted from the article]

Researchers from the First Affiliated Hospital of Wannan Medical College in China have conducted a study on hemorrhagic fever with renal syndrome (HFRS) and its complications, specifically acute pancreatitis (AP). The study analyzed the medical records of 114 individuals with HFRS, of which 26.32% had AP. The researchers identified several risk factors for HFRS complicated with AP, including a history of alcohol consumption, high lymphocyte percentage, intense proteinuria, high levels of fibrinogen degradation products (FDPs), and low levels of D-dimer. This study provides valuable insights into the risk factors associated with HFRS and AP. [Extracted from the article]

Researchers from Nanjing Medical University have conducted a study on the role of glomerular lesions in patients with acute kidney injury (AKI) during hemorrhagic fever with renal syndrome (HFRS). The study analyzed 66 patients with AKI during HFRS and found that patients with glomerular lesions or moderate renal tubulointerstitial injury had a relatively poor kidney prognosis. The presence of glomerular lesions and moderate tubulointerstitial injury were identified as independent risk factors for kidney prognosis. The study suggests that a kidney biopsy can help determine the long-term prognosis in patients with AKI during HFRS. [Extracted from the article]

FILE -- The Chinese President CAIRO, March 25 (MENA) - Spokesman for the Chinese Embassy in Cairo Jiao Jinshian said on Wednesday that reports circulated on social media on the [...]

A recent report from Soochow University in Suzhou, China discusses the rare conditions of Hemorrhagic Fever With Renal Syndrome (HFRS) and reversible splenial lesion syndrome. HFRS is characterized by symptoms such as fever, hemorrhage, and acute kidney injury. The report describes a case of a middle-aged man who was hospitalized with fever and acute neurological symptoms, with his main symptom being recurrent dizziness. Further analysis revealed that the patient had decreased platelet counts and positive hemorrhagic fever antibodies. The patient was eventually diagnosed with HFRS and showed clinical improvements after treatment. [Extracted from the article]

A recent study conducted by researchers at Jeonbuk National University Medical School and Hospital focused on the use of FDG PET/CT imaging in the diagnosis and treatment evaluation of hemorrhagic fever with renal syndrome (HFRS). The study examined the case of a 58-year-old man who presented with fever, myalgia, and dysuria. The FDG PET/CT scan revealed rapidly enlarged kidneys with intense hypermetabolism, indicating the invasion of Hantavirus and resulting nephritis. This case suggests that FDG PET/CT imaging could be a valuable tool for diagnosing and monitoring patients with HFRS. This is the first report of FDG PET/CT imaging being used in a patient with HFRS. [Extracted from the article]

A new study conducted by researchers at the Fourth Military Medical University in Xi'an, China, explores the role of HLA-E-restricted CD8+ T cells in controlling infection in hemorrhagic fever with renal syndrome (HFRS) caused by the Hantaan virus (HTNV). The study identifies six HLA-E-restricted CD8+ T cell epitopes on HTNV and investigates the characteristics and functions of these epitope-specific CD8+ T cells in HFRS patients. The findings suggest that HLA-E-restricted CD8+ T cells play a protective role during HTNV infection and indicate the potential for developing HLA-E-targeted vaccines against HTNV for diverse populations. The research was funded by the National Natural Science Foundation of China and published in the journal Biosafety and Health. [Extracted from the article]

A recent report from the University of Montpellier in France provides new data on Hemorrhagic Fever With Renal Syndrome (HFRS) caused by the Puumala virus (PUUV). The report focuses on a large outbreak of HFRS that occurred in the southern Jura Mountains in 2021, leading to numerous hospitalizations. The study investigates the circulation of PUUV in its animal reservoir, the bank vole, during this outbreak. The research found a higher abundance of bank voles in 2021 compared to previous years, as well as high levels of PUUV seroprevalence in bank voles during the outbreak. The study emphasizes the need for enhanced monitoring of PUUV circulation in host reservoir populations to inform the public and implement prevention strategies. [Extracted from the article]

The total orthohantavirus infection rate of rodents was 2.72% (9/331); the specific infection rate of specific animal species was 6.10% (5/82) for the Apodemus chevrieri, 100% (1/1) for the Rattus nitidus, 3.77% (2/53) for the Rattus norvegicus, and 12.50% (1/8) for the Crocidura dracula. Keywords: Asia; Bunyaviridae Infections; China; Epidemiology; Hantavirus Infections; Health and Medicine; Hematologic Diseases and Conditions; Hemorrhagic Fever; Hemorrhagic Fever With Renal Syndrome; Kidney; Nephrology; RNA Virus Infections; RNA Viruses; Risk and Prevention; Tropical Disease; Viral Hemorrhagic Fevers; Zoonoses; Zoonosis; Zoonotic EN Asia Bunyaviridae Infections China Epidemiology Hantavirus Infections Health and Medicine Hematologic Diseases and Conditions Hemorrhagic Fever Hemorrhagic Fever With Renal Syndrome Kidney Nephrology RNA Virus Infections RNA Viruses Risk and Prevention Tropical Disease Viral Hemorrhagic Fevers Zoonoses Zoonosis Zoonotic 459 459 1 10/09/23 20231013 NES 231013 2023 OCT 9 (NewsRx) -- By a News Reporter-Staff News Editor at TB & Outbreaks Week -- New research on hemorrhagic fever with renal syndrome is the subject of a new report. [Extracted from the article]

2020 FEB 29 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on RNA Viruses - Hantavirus have been published. According [...]

Keywords: Lons-le-Saunier; France; Europe; Bunyaviridae Infections; Diagnostics and Screening; Hantavirus; Hantavirus Infections; Health and Medicine; Hematologic Diseases and Conditions; Hemorrhagic Fever; Hemorrhagic Fever With Renal Syndrome; Kidney; Nephrology; RNA Virus Infections; RNA Viruses; Risk and Prevention; Tropical Disease; Viral; Viral Hemorrhagic Fevers; Virology EN Lons-le-Saunier France Europe Bunyaviridae Infections Diagnostics and Screening Hantavirus Hantavirus Infections Health and Medicine Hematologic Diseases and Conditions Hemorrhagic Fever Hemorrhagic Fever With Renal Syndrome Kidney Nephrology RNA Virus Infections RNA Viruses Risk and Prevention Tropical Disease Viral Viral Hemorrhagic Fevers Virology 163 163 1 07/10/23 20230714 NES 230714 2023 JUL 10 (NewsRx) -- By a News Reporter-Staff News Editor at TB & Outbreaks Week -- Fresh data on Hematologic Diseases and Conditions - Hemorrhagic Fever With Renal Syndrome are presented in a new report. Lons-le-Saunier, France, Europe, Bunyaviridae Infections, Diagnostics and Screening, Hantavirus, Hantavirus Infections, Health and Medicine, Hematologic Diseases and Conditions, Hemorrhagic Fever, Hemorrhagic Fever With Renal Syndrome, Kidney, Nephrology, RNA Virus Infections, RNA Viruses, Risk and Prevention, Tropical Disease, Viral, Viral Hemorrhagic Fevers, Virology Keywords for this news article include: Lons-le-Saunier, France, Europe, Bunyaviridae Infections, Diagnostics and Screening, Hantavirus, Hantavirus Infections, Health and Medicine, Hematologic Diseases and Conditions, Hemorrhagic Fever, Hemorrhagic Fever With Renal Syndrome, Kidney, Nephrology, RNA Virus Infections, RNA Viruses, Risk and Prevention, Tropical Disease, Viral, Viral Hemorrhagic Fevers, Virology, Department of Infectious Diseases. [Extracted from the article]

Keywords: Bunyaviridae Infections; Drugs and Therapies; Hantavirus; Hantavirus Infections; Health and Medicine; Hematologic Diseases and Conditions; Hemorrhagic Fever; Hemorrhagic Fever With Renal Syndrome; Kidney; Multiple Organ Failure; Nephrology; RNA Virus Infections; RNA Viruses; Risk and Prevention; Therapy; Tropical Disease; Viral; Viral Hemorrhagic Fevers; Virology EN Bunyaviridae Infections Drugs and Therapies Hantavirus Hantavirus Infections Health and Medicine Hematologic Diseases and Conditions Hemorrhagic Fever Hemorrhagic Fever With Renal Syndrome Kidney Multiple Organ Failure Nephrology RNA Virus Infections RNA Viruses Risk and Prevention Therapy Tropical Disease Viral Viral Hemorrhagic Fevers Virology 2069 2069 1 05/29/23 20230602 NES 230602 2023 JUN 2 (NewsRx) -- By a News Reporter-Staff News Editor at TB & Outbreaks Week -- A new study on hemorrhagic fever with renal syndrome is now available. For diseases with unknown origin such as refractory fever and diarrhea, it is crucial to differentiate them from common pathogenic infection and HV infections to provide timely treatment that improves the prognosis of patients.". [Extracted from the article]

2019 SEP 14 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Fresh data on RNA Viruses - Hantavirus are presented in a new [...]

Keywords: Bunyaviridae Infections; Epidemiology; Hantavirus; Hantavirus Infections; Health and Medicine; Hematologic Diseases and Conditions; Hemorrhagic Fever; Hemorrhagic Fever With Renal Syndrome; Kidney; Nephrology; RNA Virus Infections; RNA Viruses; Risk and Prevention; Tropical Disease; Viral; Viral Hemorrhagic Fevers; Virology EN Bunyaviridae Infections Epidemiology Hantavirus Hantavirus Infections Health and Medicine Hematologic Diseases and Conditions Hemorrhagic Fever Hemorrhagic Fever With Renal Syndrome Kidney Nephrology RNA Virus Infections RNA Viruses Risk and Prevention Tropical Disease Viral Viral Hemorrhagic Fevers Virology 475 475 1 05/15/23 20230519 NES 230519 2023 MAY 15 (NewsRx) -- By a News Reporter-Staff News Editor at TB & Outbreaks Week -- New research on hemorrhagic fever with renal syndrome is the subject of a new report. Epidemiology, Hantavirus, Hantavirus Infections, Health and Medicine, Hematologic Diseases and Conditions, Hemorrhagic Fever, Hemorrhagic Fever With Renal Syndrome, Kidney, Nephrology, RNA Virus Infections, RNA Viruses, Risk and Prevention, Tropical Disease, Viral, Viral Hemorrhagic Fevers, Virology, Bunyaviridae Infections. [Extracted from the article]

Keywords: Bunyaviridae Infections; Diagnostics and Screening; Hantavirus Infections; Health and Medicine; Hematologic Diseases and Conditions; Hemorrhagic Fever; Hemorrhagic Fever With Renal Syndrome; Kidney; Nephrology; RNA Virus Infections; RNA Viruses; Risk and Prevention; Seoul Virus; Tropical Disease; Viral; Viral Hemorrhagic Fevers; Virology EN Bunyaviridae Infections Diagnostics and Screening Hantavirus Infections Health and Medicine Hematologic Diseases and Conditions Hemorrhagic Fever Hemorrhagic Fever With Renal Syndrome Kidney Nephrology RNA Virus Infections RNA Viruses Risk and Prevention Seoul Virus Tropical Disease Viral Viral Hemorrhagic Fevers Virology 2023 MAR 6 (NewsRx) -- By a News Reporter-Staff News Editor at TB & Outbreaks Week -- Current study results on hemorrhagic fever with renal syndrome have been published. The news reporters obtained a quote from the research from Thapar Institute of Engineering and Technology: "Orthohantavirus infection may cause Hemorrhagic Fever with Renal Syndrome (HRFS), a disease that is characterized by acute kidney injury and increased vascular permeability. Bunyaviridae Infections, Diagnostics and Screening, Hantavirus Infections, Health and Medicine, Hematologic Diseases and Conditions, Hemorrhagic Fever, Hemorrhagic Fever With Renal Syndrome, Kidney, Nephrology, RNA Virus Infections, RNA Viruses, Risk and Prevention, Seoul Virus, Tropical Disease, Viral, Viral Hemorrhagic Fevers, Virology. [Extracted from the article]

http://discovermagazine.com/1997/jun/thesweatingsickn1161

http://discovermagazine.com/1993/dec/deathatthecorner320

Four virus diseases which kill thousands in the US are described, transmission and prevention noted, and statistics cited. Hantaviruses spread by mice, three forms of viral hepatitis, influenza which infects 37 million in the US yearly, and rabies are discussed. In 1994 30,000 people were vaccinated against rabies.