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6. Titanium as an Instant Adhesive for Biological Soft Tissue

Author

Okada, Masahiro, Hara, Emilio Satoshi, Yabe, tsushi, Okada, Kei, Shibata, Yo, Torii , Yasuhiro, Nakano, Takayoshi, Matsumoto, Takuya, Okada, Masahiro, Hara, Emilio Satoshi, Yabe, tsushi, Okada, Kei, Shibata, Yo, Torii , Yasuhiro, Nakano, Takayoshi, and Matsumoto, Takuya

Abstract

A variety of polymer‐ and ceramic‐based soft‐tissue adhesives have been developed as alternatives to surgical sutures, yet several disadvantages regarding the mechanical properties, biocompatibility, and handling hinder their further application particularly when applied for immobilization of implantable devices. Here, it is reported that a biocompatible and tough metal, titanium (Ti), shows instant and remarkable adhesion properties after acid treatment, demonstrated by ex vivo shear adhesion tests with mouse dermal tissues. Importantly, in vivo experiments demonstrate that the acid‐treated Ti can easily and stably immobilize a device implanted in the mouse subcutaneous tissue. Collectively, the acid‐treated Ti is shown as a solid‐state instant adhesive material for biological soft tissues, which can have diverse applications including immobilization of body‐implantable devices.

Published
2020

7. Titanium as an Instant Adhesive for Biological Soft Tissue

Author

1000070416220, Okada, Masahiro, 1000040779443, Hara, Emilio Satoshi, Yabe, Atsushi, Okada, Kei, 1000030327936, Shibata, Yo, 1000010188831, Torii, Yasuhiro, 1000030243182, Nakano, Takayoshi, 1000040324793, Matsumoto, Takuya, 1000070416220, Okada, Masahiro, 1000040779443, Hara, Emilio Satoshi, Yabe, Atsushi, Okada, Kei, 1000030327936, Shibata, Yo, 1000010188831, Torii, Yasuhiro, 1000030243182, Nakano, Takayoshi, 1000040324793, and Matsumoto, Takuya

Abstract

Okada M., Hara E.S., Yabe A., et al. Titanium as an Instant Adhesive for Biological Soft Tissue. Advanced Materials Interfaces, 7, 9, 1902089. https://doi.org/10.1002/admi.201902089., A variety of polymer- and ceramic-based soft-tissue adhesives have been developed as alternatives to surgical sutures, yet several disadvantages regarding the mechanical properties, biocompatibility, and handling hinder their further application particularly when applied for immobilization of implantable devices. Here, it is reported that a biocompatible and tough metal, titanium (Ti), shows instant and remarkable adhesion properties after acid treatment, demonstrated by ex vivo shear adhesion tests with mouse dermal tissues. Importantly, in vivo experiments demonstrate that the acid-treated Ti can easily and stably immobilize a device implanted in the mouse subcutaneous tissue. Collectively, the acid-treated Ti is shown as a solid-state instant adhesive material for biological soft tissues, which can have diverse applications including immobilization of body-implantable devices.

Published
2020

9. Outer membrane vesicles derived from Porphyromonas gingivalis induced cell death with disruption of tight junctions in human lung epithelial cells

Author

He, Yuhan, primary, Shiotsu, Noriko, additional, Uchida-Fukuhara, Yoko, additional, Guo, Jiajie, additional, Weng, Yao, additional, Ikegame, Mika, additional, Wang, Ziyi, additional, Ono, Kisho, additional, Kamioka, Hiroshi, additional, Torii, Yasuhiro, additional, Sasaki, Akira, additional, Yoshida, Kaya, additional, and Okamura, Hirohiko, additional

Published
2020
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22. Effect of Priming Time on Tensile Bond Strength to Bovine Teeth and Morphologic Structure of Interfaces Created by Self-Etching Primers.

Author

Itou, Kousuke, Torii, Yasuhiro, Takimura, Takehiko, Chikami, Kana, Ishikawa, Kunio, and Suzuki, Kazuomi

Subjects
DENTAL bonding, PRIMERS (Coating), DENTAL adhesives, DENTAL enamel, DENTIN, SCANNING electrochemical microscopy, DENTAL resins
Abstract

Purpose: The purpose of this study was to investigate the effect of priming time on bovine enamel and dentin adhesion promoted by self-etching primer systems. Materials and Methods: Two commercial self-etching primer systems, Clearfil SE Bond (SE) and Unifil Bond (UB), were used. Bovine enamel and dentin were treated with each system with various priming times (5, 20, and 60 seconds), and the tensile bond strength was measured. Scanning electron microscopic (SEM) observation was also performed to examine the effect of priming time on the morphology of the resin-tooth interface. Results: The tensile bond strength to enamel ranged from 10.6 to 14.3 MPa, and no statistically significant difference was detected among products or priming times. To dentin, UB showed the statistically significantly lowest tensile bond strength when primed for 5 seconds, 6.9 ± 1.1 MPa, but there was no significant difference between the groups primed for 20 and 60 seconds, 13.5 ± 4.1 MPa and 13.8 ± 4.6 MPa, respectively. SE created tensile bond strengths ranging from 13.9 to 15.7 MPa and showed no effect of priming time on dentin adhesion. SEM observation revealed that resin penetrated into both enamel and dentin more deeply with extension of priming time. Conclusion: Priming times longer than those recommended by the manufacturers did not influence the tensile bond strength to enamel and dentin when using two commercial self-etching primers. In contrast, a shortened priming time, 5 seconds, carried a risk of decreasing dentin adhesion, although it had no adverse effect on enamel adhesion. [ABSTRACT FROM AUTHOR]

Published
2001

25. Low-temperature polycrystalline Si film growth on amorphous insulators by reactive ion beam deposition.

Author

Yamada, Hiroshi and Torii, Yasuhiro

Subjects
*POLYCRYSTALS, *SILICON, *AMORPHOUS substances, *ELECTRIC insulators & insulation
Abstract

Investigates polycrystalline silicon growth on amorphous insulators by using the reactive ion beam deposition method. Types of amorphous insulators analyzed; Details of experimental procedures; Effects of growth temperature on polysilicon growth; Analysis of the effects of ion energy on polysilicon growth.

Published
1989
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26. Thin heteroepitaxial Si-on-sapphire films grown at 600 °C by reactive ion beam deposition.

Author

Yamada, Hiroshi and Torii, Yasuhiro

Subjects
*EPITAXY, *THIN films, *SILICON, *SAPPHIRES
Abstract

Presents a study that investigated the heteroepitaxial growth of silicon thin films on sapphire at temperature. Analysis of the film growth through a fixed ion energy; Evaluation of the growth of the thin films by accommodating the ion energy to two film growth stages; Conclusions.

Published
1988
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27. Low-temperature homoepitaxial film growth of Si by reactive ion beam deposition.

Author

Yamada, Hiroshi and Torii, Yasuhiro

Subjects
*THIN films, *SILICON, *EPITAXY, *ION bombardment
Abstract

Discusses a study which investigated the homoepitaxial film growth maintaining primary surface structures of silicon substrates using the reactive ion beam deposition method. Evaluation of impurity concentrations in the epitaxial films; Experimental procedures; Results and discussion; Conclusions.

Published
1988
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34. Occlusion: Supporting and Pacing Force Distribution

Author

Minagi, Shogo, primary, Kinuta, Yoshihiro, additional, Sejima, Junichi, additional, Hara, Tetsuya, additional, Nishigawa, Goro, additional, Maruo, Yukinori, additional, Arima, Taro, additional, Oki, Kazuhiro, additional, Oka, Morihiko, additional, Hasegawa, Koichi, additional, Kodama, Naoki, additional, Shimazu-Kodama, Chie, additional, Suwaki, Michihiro, additional, Torii, Yasuhiro, additional, and Shirai, Hajime, additional

Published
2008
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