1. Effects of 25-hydroxycholecalciferol supplementation in maternal diets on reproductive performance and the expression of genes that regulate lactation in sows.
- Author
-
Wang K, Chen Y, Zhang D, Wang R, Zhao Z, Feng M, Wei H, Li L, and Zhang S
- Subjects
- Animals, Calcium metabolism, Estrus drug effects, Female, Glycolipids metabolism, Glycoproteins metabolism, Lactation physiology, Lipid Droplets, Phosphorus metabolism, Pregnancy, RNA, Messenger genetics, RNA, Messenger metabolism, 25-Hydroxyvitamin D 2 administration & dosage, 25-Hydroxyvitamin D 2 pharmacology, Animal Nutritional Physiological Phenomena genetics, Animal Nutritional Physiological Phenomena physiology, Diet veterinary, Dietary Supplements, Gene Expression drug effects, Intracellular Signaling Peptides and Proteins genetics, Intracellular Signaling Peptides and Proteins metabolism, Lactation genetics, Membrane Proteins genetics, Membrane Proteins metabolism, Reproduction drug effects, Sterol Regulatory Element Binding Protein 1 genetics, Sterol Regulatory Element Binding Protein 1 metabolism, Swine genetics, Swine physiology
- Abstract
One hundred Yorkshire × Landrace sows were randomly assigned to one of two dietary treatments (diet ND: 6,000 IU vitamin D
3 /d feed; diet 25-D: 200 μg/day 25OHD3 feed). The experiment began on d 90 of gestation and continued until weaning on day 21 of lactation. In sows that received 25OHD3 , the growth rate of the piglets before weaning was significantly accelerated (0.266 kg/day, p < .05). Sow serum was collected after weaning, and those in the 25OHD3 group were found to have significantly higher serum calcium (CA) and phosphorus (PI) levels (p < .05). Interestingly, the oestrus cycle of sows fed 25OHD3 was significantly shortened (p < .05), the oestrus time was concentrated on the fifth day after weaning, and the piglets were born with a higher degree of uniformity (p < .05). Colostrum was collected on the day of delivery, and the colostrum of sows fed 25OHD3 contained higher milk fat content than the control group (p < .05). 25OHD3 supplementation increased the mRNA and protein expression of INSIG1 and SREBP1, which regulate milk fat synthesis, in the mammary gland of lactating sows (p < .05). In conclusion, 25OHD3 supplementation in maternal diets improved reproductive performance, milk fat content and the mRNA and protein levels of genes regulating milk fat synthesis in lactating sows., (© 2020 Japanese Society of Animal Science.)- Published
- 2020
- Full Text
- View/download PDF