1. Analysis of the relationship between periodontitis and osteoporosis/fractures: a cross-sectional study
- Author
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Soo-Hwan Byun, Seok Jin Hong, Byoung-Eun Yang, Sung-Jae Kim, Dae Myoung Yoo, and Hyo Geun Choi
- Subjects
Adult ,medicine.medical_specialty ,Cross-sectional study ,Osteoporosis ,030209 endocrinology & metabolism ,Oral hygiene ,03 medical and health sciences ,0302 clinical medicine ,Bone Density ,Internal medicine ,Epidemiology ,medicine ,Humans ,Periodontitis ,General Dentistry ,Aged ,Systemic inflammation ,business.industry ,030206 dentistry ,Odds ratio ,Middle Aged ,Oral Hygiene ,medicine.disease ,Chronic periodontitis ,lcsh:RK1-715 ,Cross-Sectional Studies ,Fracture ,lcsh:Dentistry ,Oral and maxillofacial surgery ,business ,Research Article - Abstract
Background Chronic periodontitis is a multifactorial inflammatory disease resulting in patients exhibiting high levels of inflammatory factors causing systemic inflammatory bone destruction that may lead to osteoporosis development. The association between periodontitis and osteoporosis has been documented; however, the findings remain unclear. This study aimed to identify the association between periodontitis and osteoporosis using a cross-sectional study design and Korean Genome and Epidemiology Study (KoGES) health examinee data. Methods This cross-sectional study used epidemiological data from the KoGES during 2004–2016. Of 125,324 participants (age, 40–79 years), 9969 with periodontitis and 115,332 controls (without periodontitis) were selected. We analyzed the history of osteoporosis and fractures of all participants. All participants were examined according to age, sex, income group, obesity, smoking habits, alcohol consumption, and food intake. To analyze the odds ratio (OR) of periodontitis for those with osteoporosis and fractures, a logistic regression model was used. Results The adjusted odds ratio (aOR) of periodontitis for osteoporosis was 2.16 (95% confidence interval [CI], 2.01–2.31; P P Conclusion Osteoporosis and fractures are associated with periodontitis. Performing regular oral hygiene and examinations of bone mineral density are recommended to prevent aggravation of osteoporosis and periodontitis.
- Published
- 2021