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Increased Risk of Temporomandibular Joint Disorder in Patients with Rheumatoid Arthritis: A Longitudinal Follow-Up Study
- Source :
- Journal of Clinical Medicine, Vol 9, Iss 3005, p 3005 (2020), Journal of Clinical Medicine, Volume 9, Issue 9
- Publication Year :
- 2020
- Publisher :
- MDPI AG, 2020.
-
Abstract
- We evaluated the incidence of temporomandibular disorder (TMD) in patients with rheumatoid arthritis (RA) and examined the association between TMD and RA, through longitudinal follow-up. Population data from the Korean National Health Insurance Service-Health Screening Cohort from 2002 to 2015 was used. From 514,866 subjects, 3122 with RA were matched with 12,488 controls in a 1:4 ratio. The crude and adjusted models (for obesity, smoking, alcohol consumption, blood pressure, blood glucose, total cholesterol, and Charlson Comorbidity Index scores) were calculated. Chi-square tests, Kaplan-Meier (KM) analysis, and two-tailed analyses were used for statistical analysis. Stratified Cox proportional hazard models were used to assess the hazard ratios (HR) and 95% confidence intervals (CI) for TMD in the RA group, compared to those in the control group. The adjusted HR for TMD in RA was 2.52 (95% CI = 1.70&ndash<br />3.74), compared to the control group. The results were consistent with the subgroup analyses, according to age and sex, except in men older than 60 years of age. KM analysis showed similar results. Hence, we found that patients with RA have a higher risk of TMD, and should be observed for symptoms of the initial stage of TMD to prevent the risk of aggravation.
- Subjects :
- rheumatoid arthritis
medicine.medical_specialty
lcsh:Medicine
Article
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
Temporomandibular Joint Disorder
temporomandibular joint
030203 arthritis & rheumatology
business.industry
Incidence (epidemiology)
TMD
lcsh:R
Hazard ratio
disorder
030206 dentistry
General Medicine
TMJ
medicine.disease
Obesity
Confidence interval
stomatognathic diseases
Blood pressure
Rheumatoid arthritis
Cohort
business
Subjects
Details
- ISSN :
- 20770383
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Medicine
- Accession number :
- edsair.doi.dedup.....4682d124f61a97eefeaacb4245a37931