1. Clinical features and epidemiology of severe fever with thrombocytopenia syndrome in dogs in the Republic of Korea: an observational study (2019–2020)
- Author
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Sun-Woo Han, Ye-In Oh, Ji-Min Rim, Yoon-Kyoung Cho, Dong-Hoo Kim, Jun-Gu Kang, Kyoung-Seong Choi, and Joon-Seok Chae
- Subjects
Phlebovirus ,Dogs ,Severe Fever with Thrombocytopenia Syndrome ,General Veterinary ,Republic of Korea ,Humans ,Animals ,Dog Diseases ,General Medicine ,Bunyaviridae Infections ,Thrombocytopenia ,Phylogeny - Abstract
Severe fever with thrombocytopenia syndrome (SFTS) is a zoonotic disease with a high mortality rate for humans and cats. The clinical course and prognosis of SFTS in dogs remains unclear. In the present study, we investigated the clinical and epidemiological characteristics of SFTS virus (SFTSV) infection in dogs. All evaluated dogs exhibited an acute course and symptoms including fever (57.1%), anorexia (57.1%), depression (42.9%), and vomiting (35.7%). Thrombocytopenia was present in 45.5% of dogs, while jaundice was not observed. C-reactive protein, alanine transaminase, and alkaline phosphatase were elevated in some cases. Viral clearance occurred within 6 to 26 days. Phylogenetic analysis revealed that the SFTSV sequences were consistent with viruses circulating in the Republic of Korea. As dogs often live in close contact with humans, awareness of the clinical and epidemiological features of SFTS in dogs is crucial. Further large-scale studies are necessary to investigate SFTSV infection in dogs.
- Published
- 2022