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The article discusses the use of NBBC (Non-B DNA Burden in Cancer) as a tool to quantify and analyze non-B DNA motifs in cancer research. It provides a step-by-step protocol for utilizing NBBC to explore correlations between non-B DNA structures and cancer biology, including DNA damage repair pathways and gene mutation signatures. The article emphasizes the importance of understanding the potential role of non-B DNA in cancer biomarker investigations. [Extracted from the article]

Northwestern Mutual, a financial services company, has declared September 4th as "goldeNMoments Day" in Milwaukee to commemorate Childhood Cancer Awareness Month. The company has been dedicated to accelerating the search for better treatments and cures for childhood cancer for the past 12 years. Through its Foundation, Northwestern Mutual has raised over $3.6 million in 2024 to support the cause. This initiative aims to shed light on the stories of resilience, research breakthroughs, and survivorship in the fight against childhood cancer. [Extracted from the article]

A recent report from Kyungpook National University in South Korea explores the role of the collagen family in the progression of cervical cancer. The researchers used RNA-seq data analysis and the Mclust algorithm to identify 24 epithelial-to-mesenchymal transition (EMT)-related genes, with 5 showing strong associations with cervical cancer prognosis. The study suggests that EMT, Matrix Metallopeptidase 2 (MMP2), and extracellular matrix (ECM) degradation are interconnected, ultimately leading to collagen type VI and exacerbating the prognosis of cervical cancer. Collagen type VI also emerges as a potential gene marker for the prognosis of cervical cancer. [Extracted from the article]

A report from Changsha Medical University in Hunan, China discusses the role of the LMO7 gene in various types of cancer. The research highlights the importance of LMO7 in tumor development and progression, and explores its potential as a therapeutic target and prognostic indicator. The study also acknowledges the challenges and future prospects of targeting LMO7 for cancer treatment. The research has been peer-reviewed and provides valuable insights into the molecular mechanisms of cancer. [Extracted from the article]

A recent preprint abstract published on biorxiv.org discusses a comprehensive genetic catalog of human double-strand break (DSB) repair. The study utilized in-pool profiling of Cas9-induced indels within a genome-wide knockout library to analyze DNA sequence outcomes and gain insights into DSB repair mechanisms. The researchers identified novel mechanisms, pathways, and factors involved in DSB repair, including unexpected roles for XLF and PAXX in DNA end processing, the involvement of HLTF as a DSB-repair factor, and the identification of an indel mutational signature linked to VHL loss, renal carcinoma, and hypoxia. The findings highlight the potential of this research to drive future discoveries in DSB repair, CRISPR-Cas gene editing, and the understanding of cancer mutational signatures. [Extracted from the article]

A new report from the University of Limerick discusses research findings on prostate cancer. The study aimed to understand the experiences and perspectives of individuals with prostate cancer and their partners. The research identified four themes: quality of life, relationships and dynamics, treatment journey, and survivorship and aftercare. The study concluded that prostate cancer has a significant impact on patients and partners, highlighting the need for comprehensive support, tailored assistance, and research into minimizing adverse effects and addressing emotional distress. The findings emphasize the importance of emotional support, education, and presurgery support for patients and partners facing fears of recurrence and lifestyle changes. [Extracted from the article]

A recent study conducted by researchers at Catholic University investigated the potential link between humidifier disinfectants (HDs) and lung cancer. While HDs have been associated with respiratory diseases, their connection to lung cancer is not well understood. The study analyzed a cohort of 7,343 individuals who reported health damage from HD exposure and found that the standardized incidence ratios (SIRs) of lung cancer were higher in both men and women compared to the general population. Although the study has limitations, it provides valuable insights into the potential association between HDs and the development of lung cancer. [Extracted from the article]

A new report discusses research findings on cancer incidence and etiology in the active duty population of the US military. The study suggests that active duty service members (ADS) represent a healthy population with a low risk of cancer, but over 800 ADS are diagnosed with cancer each year. Melanoma is the most common cancer in ADS, while testicular cancer is the most common in males and breast cancer is the most common in females. The etiology of cancer in ADS is largely unknown, but research programs are being developed to improve understanding and outcomes. [Extracted from the article]

A recent literature review conducted by researchers at the University of Medicine and Pharmacy explores the risk factors and therapeutic aspects of oral cancer. The study highlights the multifactorial nature of the disease, with systemic factors such as age, gender, heredity, race, socio-economic status, and immunodeficiency, as well as local factors like tobacco and alcohol use, chronic traumas, chronic infections, and the role of viruses, contributing to its onset and progression. The review also discusses potential prevention strategies, including the use of probiotics, vitamins, omega-3 fatty acids, and compounds like curcumin, as well as the potential benefits of the Mediterranean diet. The study emphasizes the complexity of oral cancer and the need for a nuanced approach to treatment planning. [Extracted from the article]

A recent report from Wroclaw Medical University in Poland discusses the research findings on hypercalcemia, a condition characterized by elevated calcium levels in the blood. The report highlights the importance of calcium in maintaining homeostatic balance and functioning of living organisms. Hypercalcemia can occur as a result of pathologies such as cancer and can affect over 40% of cancer patients. The main mechanism of hypercalcemia in tumors is believed to be excessive production of parathyroid hormone-related peptides. Treatment methods include bisphosphonates, calcitonin, steroids, and denosumab, with ongoing research aiming to advance pharmacotherapy. The rising global prevalence of cancer makes hypercalcemia an important issue that requires attention. [Extracted from the article]

A preprint abstract from medrxiv.org discusses a novel method for analyzing the causes of breast cancer and autism. The method uses a special algorithm based on math to combine multiple research studies on risk factors and physiology to determine the causes of non-infectious diseases. The method identifies physiological parameter changes beyond a certain threshold and disease causation factors that contribute to the development of the diseases. The study applies this method to breast cancer and autism, finding that breast cancer has four simultaneous causes and autism has two causes for boys and three causes for girls. The method also suggests that recent increases in autism may be due to the removal of defensive mechanisms. The article provides formulas and an analogy to explain the method and encourages other researchers to use it to study non-infectious diseases. [Extracted from the article]

A recent report from Osnabruck University in Germany highlights the increasing threat of skin cancer, particularly among fair-skinned populations worldwide. The study focuses on the prevention of occupational skin cancer caused by solar ultraviolet radiation exposure, which is a common occupational carcinogenic exposure for outdoor workers. The researchers emphasize the importance of sun protection in the workplace and suggest that existing prevention strategies should be enhanced with new educational concepts, methods, and technologies. The study calls for a comprehensive approach to prevention, including general prevention, individual prevention, setting-based prevention, and behavior-based prevention. [Extracted from the article]

A recent study conducted at Suresh Gyan Vihar University in Jaipur, India, has explored the role of circular RNAs (circRNAs) in cancer therapy. The research highlights the diverse functions of circRNAs, including their influence on ferroptosis, a process that affects cancer cell survival, proliferation, and metastasis. The study suggests that targeting specific circRNAs associated with cancer could lead to the development of targeted therapeutics. This research contributes to the understanding of ferroptosis and circRNAs in cancer therapy and encourages further investigation in this field. [Extracted from the article]

A preprint abstract from biorxiv.org discusses the dysfunction of natural killer (NK) cells in bladder cancer patients. The study found that NK cells derived from bladder tumors exhibited severe dysfunction compared to NK cells from peripheral blood. The over-expression of inhibitory receptors in both peripheral and tumor-infiltrating NK cells did not explain the observed defects in NK surveillance in bladder tumors. Instead, tissue-specific factors such as TGF-{beta} and metabolic perturbations like hypoxia directly suppressed NK cell function. The study suggests that targeting SLAMF6 signaling could be a potential strategy to improve NK cell function in bladder cancer. However, it is important to note that this preprint has not been peer-reviewed. [Extracted from the article]

A report from Uppsala University discusses research findings on breast cancer and immune checkpoint blockade therapy. The study focuses on triple-negative breast cancer (TNBC) and reveals that the loss of the NEDD8 gene in cancer cells makes them vulnerable to nivolumab, an anti-PD-1 drug. The researchers found that NEDD8 deficiency enhances immunogenicity in cancer cells and leads to tumor regression mediated by CD8+ T cells after PD-1 blockade. This study suggests that NEDD8 could be a potential drug target for TNBC treatment. [Extracted from the article]

A recent study conducted by researchers at Hashemite University in Zarqa, Jordan, aimed to evaluate the level of awareness among adult females in northern Jordan regarding breast cancer risk factors and potential causes. The study found that the majority of participants had a good understanding of breast cancer risk factors, but there is still a need for ongoing medical education programs to further improve knowledge. Breast cancer is the most prevalent type of cancer among women in both industrialized and developing nations. The study's findings suggest that North Jordanian women are well-informed about breast cancer, but there is room for improvement in knowledge dissemination. [Extracted from the article]

A recent study conducted by the Department of Pediatrics highlights the childhood risk factors for pediatric cancer. The researchers conducted literature searches and found strong evidence linking genetic and epigenetic phenomena, structural birth defects, and chromosomal anomalies to an increased risk of childhood cancers. Previous cancer and exposure to ionizing radiation were also identified as risk factors. The study also found that childhood vaccination against carcinogenic viruses is associated with a lower risk of several cancers. However, evidence for other factors such as body mass index, childhood infections, and certain treatments was weak or conflicting. The study provides valuable insights into the causes of childhood cancer and can be accessed for free online. [Extracted from the article]

A recent study conducted by researchers at Georgetown University Medical Center focused on breast cancer and the development of resistance to estrogen receptor-positive therapies. The study found that altered metabolism and an increased reliance on glycolysis are characteristic of cancer cells, and the enzyme PFKFB3 plays a crucial role in regulating glycolytic flux. The researchers demonstrated that inhibiting PFKFB3 can induce necroptosis, a form of cell death, in endocrine-resistant breast cancer cells. However, silencing genes involved in necroptosis prevented this cell death, contributing to resistance. This study highlights the importance of understanding the mechanisms of resistance in breast cancer and the potential for targeting PFKFB3 as a therapeutic strategy. [Extracted from the article]

A recent study conducted by researchers at the Memorial Sloan-Kettering Cancer Center has shed light on the causes of medulloblastoma, a common brain tumor in children. The study found that PiggyBac transposable element derived 5 (Pgbd5) promotes tumor development in mouse models of Sonic Hedgehog (SHH) medulloblastoma. The researchers discovered that medulloblastomas expressing Pgbd5 had increased numbers of somatic structural DNA rearrangements, providing a genetic mechanism for the generation of oncogenic DNA rearrangements in childhood cancer. This research contributes to a better understanding of the mutagenesis of childhood cancer. [Extracted from the article]

A recent study conducted by researchers at Jinzhou Medical University in China explored the diagnostic value of multi-slice spiral computed tomography dynamic enhanced scanning (MSCT) for lymph node metastasis in cervical cancer. The study analyzed 283 patients with cervical cancer and compared the results of MSCT with surgical and pathological examinations. The study found that MSCT had a high diagnostic value, with a positive coincidence rate of 92.75% and a total coincidence rate of 81.98%. The research concluded that factors such as a high degree of differentiation, negative Ki-67 expression, and interstitial infiltration depth were associated with missed diagnoses. This research has been peer-reviewed and published in the European Journal of Gynaecological Oncology. [Extracted from the article]

Cleveland Clinic researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV) to induce cancer. The virus manipulates two human enzymes, CDK6 and CAD, to alter cell metabolism and proliferation, increasing the risk of tumor formation. The researchers found that inhibiting this process with existing FDA-approved breast cancer drugs reduced KSHV replication, blocked lymphoma progression, and shrank tumors in preclinical models. These findings have implications for treating KSHV-associated cancers and potentially other cancer-associated viruses that use similar mechanisms. [Extracted from the article]

A study conducted by Zhejiang University School of Medicine in Hangzhou, China, explores the potential of long non-coding RNAs (lncRNAs) in breast cancer. The researchers highlight the complexity and molecular heterogeneity of breast cancer, emphasizing the need for different treatment strategies for various subtypes. The study discusses the roles and mechanisms of lncRNAs in breast cancer progression, metastasis, and treatment resistance, as well as their potential as diagnostic biomarkers and therapeutic targets. The researchers also propose lncRNA-based strategies to improve the prognosis of breast cancer patients, including the development of novel lncRNA-targeted therapies. [Extracted from the article]

A recent report from the University of Torino in Italy discusses the frequent mutations in the RAS-RAF-MEK-ERK pathway in cancer and RASopathies. While RAS oncogene activation affects 19% of all patients and accounts for approximately 3.4 million new cases every year, less common alterations in the pathway's downstream effectors are also involved in cancer development. The report explores recent advances in anti-RAF therapies, including paradox breakers, dimer-inhibitors, immunotherapies, and other novel approaches, evaluating their efficacy in overcoming therapeutic limitations and their potential role in blocking the RAS pathway. This research provides valuable insights into potential treatments for different types of malignancies. [Extracted from the article]

A recent study conducted by Fudan University in Shanghai, China, assessed the risk of lung cancer caused by indoor radon exposure in 15 cities in China from 2006 to 2016. The study found that the risk of lung cancer attributed to indoor radon exposure has increased since 2010. The population attributable risk in 2016 ranged from 6.66% to 22.42%, with a median of 15.33% for the 15 cities. The study also found that the risk of lung cancer caused by indoor radon was higher in males and the 40-45 age group. This research provides valuable insights into the impact of indoor radon exposure on lung cancer incidence in China. [Extracted from the article]

A new study conducted by researchers at the Albert Einstein College of Medicine in Bronx, New York, has examined the epidemiologic and clinical characteristics of nonbacterial thrombotic endocarditis (NBTE), a condition characterized by fibrin depositions on cardiac valves. The study analyzed 416 case reports and series, finding that stroke-like symptoms were the most common presentation and embolic phenomena occurred in 70% of cases, primarily due to stroke. The study also revealed that cancer was associated with higher embolic complications and mortality rates compared to other NBTE etiologies. However, there has been a decrease in NBTE mortality in recent years. The researchers concluded that while overall mortality rates have improved, cases associated with cancer still have high morbidity and mortality during hospitalization. [Extracted from the article]

A new report discusses research findings on breast cancer, specifically focusing on the delay in initiating treatment after diagnosis. The study, conducted at Ekiti State University, found that 42.5% of breast cancer patients experienced delays in starting oncologic treatments. The median durations of symptoms at presentation and between diagnosis and treatment initiation were 6 and 10 months, respectively. The main reasons for delayed treatment included the use of alternative therapy, financial problems, fear of surgery, chemotherapy side effects, and family interference. The study emphasizes the importance of addressing the causes of patient delay in addition to early detection and diagnosis. [Extracted from the article]

A recent report from Diponegoro University in Semarang, Indonesia discusses the findings of a study on tongue cancer. The research highlights that oral squamous cell carcinoma (OSCC) is a common form of tongue cancer, usually diagnosed in individuals over the age of 60. The study suggests that chronic mechanical trauma, such as sharp teeth, may be a contributing factor to the development of OSCC. The report emphasizes the importance of early diagnosis in preventing metastasis and improving the quality of life for patients. For more information, the full article can be accessed through the Dental Journal website. [Extracted from the article]

A recent study conducted at Queen's University in Kingston, Canada explored the beliefs of cancer survivors regarding the causes of their cancer. The study found that the most commonly believed causes of cancer among the participants were stress or worry, pollution in the environment, and chance or bad luck. The study also identified characteristics of survivors who were more likely to believe certain factors caused their cancer. The findings of this research can be used to inform cancer education and risk-reduction campaigns, and to target initiatives towards specific groups of survivors. [Extracted from the article]

A recent study conducted at the University of Texas El Paso explores the role of the Mitogen Activated Protein Kinase (MAPK) pathway in gene expression regulation and its connection to cancer and neurodegenerative disorders. The MAPK pathway is a cellular signaling pathway that controls various cellular processes. Dysregulation of this pathway and genetic alterations in its components can lead to the development of cancer and neurodegenerative disorders. The study provides an update on the progress of understanding the MAPK pathway and its implications for disease. [Extracted from the article]

A recent report from Central South University in Guilin, China, explores the impact of sex on bladder cancer. The research examines the etiology, biology, diagnosis, and outcomes of bladder cancer, highlighting the influence of sex on its incidence and clinical outcomes. The report delves into various factors such as tobacco consumption, occupational exposures, genetic aberrations, sex hormones, sex chromosomal dynamics, metabolic enzymatic cascades, and the interplay with the microbiome. The researchers emphasize the need for further investigation into gender-specific variances and the development of tailored therapeutic strategies. [Extracted from the article]

A recent study conducted by researchers at the University of Utah evaluated the accuracy of race and Hispanic ethnicity data collected by the Utah Cancer Registry compared to self-reporting. The study found that there were discrepancies between the registry-collected data and self-reported values, particularly for individuals identifying as American Indian or Alaska Native (AIAN). The researchers concluded that hospitals should continue to focus on accurately capturing race and ethnicity data. This research has been peer-reviewed and published in Cancer Causes & Control. [Extracted from the article]

A recent study conducted by researchers at New York University (NYU) highlights the prevalence of pain associated with breast cancer and its negative impact on patients' quality of life. The study emphasizes that breast cancer pain is not only caused by the disease itself but also by current therapeutic strategies. The researchers provide a comprehensive overview of the different sources of pain in breast cancer, including the disease process and treatments such as radiation, chemotherapy, immunotherapy, and surgery. The study also discusses the limitations of current pain management techniques and explores potential novel analgesic strategies. For more information, readers can access the full article published in Frontiers in Pain Research. [Extracted from the article]

A study conducted by Northwestern University examined the prevalence of cancer fatalism among different Asian origin groups. Cancer fatalism refers to beliefs about the external causes of cancer and the perceived inability to prevent it. The study utilized nationally representative survey data and found that Filipino adults had nearly double the prevalence of cancer fatalism beliefs compared to Indian adults. Vietnamese adults also exhibited high levels of cancer fatalism beliefs. The findings highlight the heterogeneity among Asian American origin groups and emphasize the need for culturally tailored interventions to address these beliefs. [Extracted from the article]

A recent qualitative study conducted by researchers from Universidad Cooperativa de Colombia aimed to understand the social representations of cancer in patients from Medellin, Colombia. The study found that at the time of diagnosis, cancer evokes negative connotations, but as the disease progresses and patients interact with health professionals and respond to treatment, it is redefined as a positive event. The way patients understand and represent cancer is influenced by cultural meanings and personal experiences, and their beliefs about the causes of cancer impact their treatment-seeking behaviors. The study also highlighted the hidden burdens faced by individuals immersed in a context where the ideology of happiness is a social norm. [Extracted from the article]

Researchers at the Second Affiliated Hospital of Fujian Medical University in China have conducted a study on endometrial cancer (EC) and its risk factors. They found that EC is one of the most common gynecological cancers and is associated with obesity, metabolic issues, genetics, and other factors. The researchers also discovered a link between EC and circadian rhythm disorders (CRDs), particularly in relation to night work. They suggest that changes in the circadian rhythm, regulated by clock genes (CGs) and non-coding RNAs (ncRNAs), may contribute to the development of EC. This study explores the relationship between EC, CRDs, and ncRNAs. [Extracted from the article]

A recent study conducted by researchers from the University of California San Diego (UCSD) has provided new insights into the causes and consequences of complex chromosome rearrangements in cancer. The study focused on a type of rearrangement called chromothripsis, which involves massive and localized rearrangements of one or a few chromosomes. The researchers found that chromothripsis can be initiated by mitotic errors, leading to the inactivation of tumor suppressor genes, activation of proto-oncogenes, or gene amplification. The study also highlighted the link between chromothripsis and extrachromosomal DNA. This research has been peer-reviewed and published in Nature Reviews Genetics. [Extracted from the article]

A preprint abstract from biorxiv.org discusses the importance of understanding the dynamics of genetic mechanisms that cause cancer. The authors propose a novel causal method for identifying collaborative networks of cancer drivers based on dynamic system analysis. They applied this method to breast cancer datasets and found that it systematically identifies driver genes and detects sets of genes strongly linked to cancer progression. The preprint has not been peer-reviewed. [Extracted from the article]

A study conducted by the Department of Oncology and Hematology in China analyzed the long-term changes in the burden of lung cancer caused by residential radon exposure. The study used time series data from 1990 to 2019 and found that age-standardized mortality rates and disability-adjusted life years (DALYs) rates for lung cancer caused by radon exposure increased overall, with higher rates in males compared to females. The study concluded that there is a need for proactive measures to reduce radon exposure, particularly among the elderly population and male patients. [Extracted from the article]

A report from the University of Florida College of Medicine discusses the influence of bacterial communities in the gastrointestinal tract on the development of colorectal cancer (CRC). The research highlights specific bacterial species that may increase the risk of CRC, such as Fusobacterium nucleatum, Enterotoxigenic Bacteroides fragilis, and pks+ E. coli. The review also explores how host-bacteria interactions can be utilized for the diagnosis, prevention, and treatment of CRC. For more information, readers can refer to the journal article "Intestinal bacteria and colorectal cancer: etiology and treatment" published in Gut Microbes. [Extracted from the article]

A new report from researchers at Kumamoto University in Japan highlights the increasing incidence of early-onset cancers in various organs, including the digestive system. While some cases are associated with genetic factors, the majority are sporadic and multifactorial. The exact contributions of diet, lifestyle, environment, and the microbiome in the development of these cancers remain uncertain. The study calls for transdisciplinary research approaches to better understand the etiology of early-onset cancers and develop effective prevention and treatment strategies. [Extracted from the article]

A new study conducted at the King Hussein Cancer Centre in Jordan explores the causes and implications of optic disc swelling in cancer patients. The retrospective study analyzed data from cancer patients with optic disc swelling between January 2019 and December 2020. The study found that optic disc swelling can be caused by various underlying pathologies, with tumor infiltration of the optic nerve resulting in more severe visual impairment compared to papilledema due to elevated intracranial pressure. Timely detection and treatment are crucial to prevent irreversible optic nerve damage and vision loss in cancer patients. [Extracted from the article]

A recent study conducted by the International Agency for Research on Cancer in Lyon, France, explores the application of metabolomics to population-based studies in order to gain a better understanding of breast cancer etiology. The research found that specific lipids and amino acids were commonly associated with breast cancer development. However, the comparison of results across studies is challenging due to variations in laboratory techniques, sample size, and statistical methods. The study concludes that larger sample sizes and more detailed information on menopausal status and breast cancer subtypes are needed to improve the comparison and validation of results, allowing for potential clinical translation of findings. [Extracted from the article]

The American Cancer Society (ACS) and Color Health have partnered to launch a program aimed at increasing access to lung cancer screening for millions of Americans. The program is designed to make it easier for individuals who smoke or have smoked in the past to determine their eligibility for screening and find screening options. Lung cancer is the leading cause of cancer death in the United States, and annual screening with low-dose CT scans can reduce lung cancer deaths by up to 20%. However, less than 6% of eligible Americans currently get screened, often due to difficulties navigating the healthcare system and the stigma associated with lung cancer. The new program aims to overcome these barriers and increase the number of eligible Americans who receive screenings. [Extracted from the article]

A recent study conducted at the University of California San Francisco (UCSF) explored the use of crofelemer, an anti-diarrheal medication, in managing neratinib-induced diarrhea in patients with early-stage HER2+ breast cancer. The study found that crofelemer was effective in controlling diarrhea, with five out of seven patients being able to manage their symptoms using crofelemer alone. However, further research is needed to fully understand the potential of crofelemer in treating diarrhea caused by cancer treatment. This study provides valuable insights into the management of neratinib-associated diarrhea and highlights the need for additional investigation in this area. [Extracted from the article]

A study conducted by Shiraz University of Medical Sciences in Iran investigated the concentration and risk of carcinogenic and non-carcinogenic causes due to skin and drinking exposure to water in 27 points of potable water in Shiraz. The study found that the concentration of all parameters was higher in winter compared to summer, but still lower than the standards set by Iran, the World Health Organization (WHO), and the United States Environmental Protection Agency (USEPA). The research also revealed that the risk of cancer and non-cancer caused by heavy metals in children due to dermal and drinking exposure was higher than in other groups. However, the overall chemical quality of water in the city was deemed to be optimal. [Extracted from the article]

A study conducted by scientists at the Ontario Institute for Cancer Research (OICR) has found that smoking can cause cancer and make it more difficult to treat by interfering with the body's anti-cancer defenses. The study, published in Science Advances, reveals that smoking leads to harmful changes in DNA known as "stop-gain mutations," which prevent the formation of certain proteins that would normally prevent abnormal cell growth. The researchers analyzed DNA from over 12,000 tumor samples and found a strong link between stop-gain mutations in lung cancer and the DNA footprint left by smoking. The study also suggests that factors such as unhealthy diet and alcohol consumption may have similar damaging effects on DNA. OICR President Dr. Laszlo Radvanyi emphasizes that these findings highlight the significant harm caused by smoking and the importance of quitting. [Extracted from the article]

This document provides information about a clinical trial conducted by the University of Arizona to study the effectiveness of two treatments, CT-guided bilateral pudendal nerve cryoneurolysis and percutaneous image-guided cryoneurolysis, for relieving severe and long-lasting pelvic pain caused by cancer. The trial aims to evaluate the efficacy, outcomes, and potential side effects of these treatments. Patients who are already undergoing the first treatment will be enrolled in the study, and if it is not effective, they will be offered the second treatment. The trial is estimated to be completed in November 2027 and is focused on improving pain management for individuals with pelvic cancer malignancy. [Extracted from the article]

Dallas, State:Texas, United States, North and Central America, Amino Acids, Aromatic Amino Acids, Cancer, Essential Amino Acids, Health and Medicine, Oncology, Tryptophan Keywords: Dallas; State:Texas; United States; North and Central America; Amino Acids; Aromatic Amino Acids; Cancer; Essential Amino Acids; Health and Medicine; Oncology; Tryptophan EN Dallas State:Texas United States North and Central America Amino Acids Aromatic Amino Acids Cancer Essential Amino Acids Health and Medicine Oncology Tryptophan 661 661 1 10/30/23 20231031 NES 231031 2023 OCT 31 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- Investigators discuss new findings in Cancer. [Extracted from the article]