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Researchers at China Jiliang University have developed a triplex loop-mediated isothermal amplification-lateral flow dipstick (LAMP-LFD) assay to detect three bovine diarrhea syndrome viruses simultaneously. The study aims to address the significant impact of these viruses on the global livestock industry. The assay showed high sensitivity and specificity, making it a promising tool for quick identification of these viruses in the field without the need for complex laboratory equipment. The research has been peer-reviewed and offers valuable insights into combating bovine viral diarrhea syndrome. [Extracted from the article]

A patent has been issued to Auburn University for the use of pectin or pectin-related saccharides to enhance the efficacy of plant growth-promoting rhizobacteria (PGPR) strains in promoting growth and health in plants and animals. PGPR are root-associated bacteria that can colonize the root system of plants and provide benefits such as plant growth promotion and biological disease control. The patent describes compositions and methods that involve the use of PGPR expressing a protein associated with pectin metabolism and a saccharide containing pectin or a pectin-related saccharide. These compositions can be used to treat plants, seeds, and soils to improve plant growth and health, as well as administered to animals to improve animal growth and health. The patent also includes methods for controlling pests of plants using Bacillus velezensis and a saccharide comprising pectin or a pectin-related saccharide. [Extracted from the article]

A patent application has been submitted for a method to produce immunoglobulin preparations against SARS-CoV-2, the virus that causes COVID-19. The method involves immunizing dairy cows with virus-derived proteins and collecting their colostrum, which contains antibodies effective against the virus. The antibodies are then isolated and prepared for use as an intranasal treatment. This method aims to provide prophylactic treatments and compositions for protecting vulnerable populations against SARS-CoV-2 infections. [Extracted from the article]

A patent application has been filed for a pharmaceutical composition that includes a lipase inhibitor to prevent or treat RNA viral infections. The composition has demonstrated effectiveness against a wide range of viruses in laboratory and animal studies. The application emphasizes the impact of RNA viruses on human and animal health, as well as the economic consequences of viral zoonotic diseases. The invention aims to target cellular factors necessary for viral replication and offer a prophylactic or therapeutic solution for RNA viral infections. The composition may also include other antiviral agents such as oseltamivir and remdesivir. Specific RNA viruses that can be targeted include SARS coronaviruses, influenza A virus, bovine coronavirus, porcine epidemic diarrhea coronavirus, and others. The patent application provides details on specific compounds and derivatives of the lipase inhibitor that can be used in the composition. [Extracted from the article]

A patent application has been filed for a vector that can produce circular RNA (circRNA) that is translatable and biologically active in eukaryotic cells. The circRNA produced by this vector can have therapeutic or diagnostic applications, such as acting as an miRNA sponge or encoding specific proteins. The vector can also be used for gene editing purposes. The patent application provides detailed information about the structure and characteristics of the circular RNA molecule, and its potential use in treating diseases. [Extracted from the article]

A recent study conducted by researchers from the National Institute of Agricultural Technology in Buenos Aires, Argentina, focused on Bovine Respiratory Syncytial Virus (BRSV), which affects both beef and dairy cattle. The study aimed to develop a recombinant MVA vaccine expressing the BRSV F protein (MVA-F) and evaluate its immune response in mice. The results showed that MVA-F induced neutralizing antibodies and IFN-y secretion, suggesting its potential as a vaccine candidate. Further evaluations combining intranasal and intramuscular routes are recommended to improve vaccine efficacy against BRSV infection. [Extracted from the article]

A recent meta-analysis examined the global prevalence of Cryptosporidium infections in cattle and the distribution of the C. parvum genotype. Cryptosporidium is a parasite that causes a severe diarrheal disease in both humans and livestock. The study found that Cryptosporidium infection has a global prevalence of 25.5% in cattle, with C. parvum being the most commonly identified species. The research highlights the importance of monitoring and reporting Cryptosporidium in cattle due to the public health risk and economic burden it poses. Efforts should be made to reduce prevalence and limit zoonotic transmission. [Extracted from the article]

A recent study published in the Journal of Dairy Science has found that current strategies to control Salmonella Dublin in Danish cattle are ineffective. Despite movement restrictions among cattle farms, the disease continues to spread. The researchers analyzed 11 years of data and found that disease transmission between farms persists, with cattle movement being a strong predictor of farm infections. The study calls for a multifaceted approach to managing Salmonella Dublin, as current measures are insufficient. This has implications for farmers, who remain at risk of infection despite adhering to restrictions, and policymakers, who need to develop more effective disease management strategies. [Extracted from the article]

A recent report from researchers in Pullman, Washington highlights the impact of bovine anaplasmosis, a tick-borne disease that affects cattle worldwide. The disease leads to high costs due to treatment, decreased production, and outbreaks resulting in high mortality. The researchers focused on identifying adhesins, proteins that mediate adhesion to host cells, specifically red blood cells (RBCs), which are relevant vaccine candidates. They identified several potential adhesins, including Msp1b and OmpA, which are known adhesins for bovine RBCs and tick cells, respectively. These findings may contribute to the development of a recombinant vaccine for bovine anaplasmosis. [Extracted from the article]

A recent study conducted by researchers at the University of California Davis examined the factors associated with perceived Anaplasma marginale infection and clinical anaplasmosis cases on beef operations in California. The study used a survey tool to gather information on anaplasmosis prevention and control management, as well as the extent to which management activities were influenced by perceived herd-level exposure to A. marginale infection or occurrence of clinical anaplasmosis cases. The results showed that there is a need for producer education to improve awareness of bovine anaplasmosis and implement proper measures for disease control and prevention. [Extracted from the article]

Researchers from Fujian Agricultural and Forestry University in Fuzhou, China have developed a colloidal gold immunochromatographic strip for the simultaneous detection of porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV). These viruses cause similar clinical symptoms in pigs, such as watery diarrhea and vomiting, and co-infections are common. The strip showed no cross-reactivity with other porcine viruses and had a high specificity and stability. The researchers concluded that the strip is a rapid and reliable tool for on-site preliminary diagnosis of PEDV- and TGEV-associated diarrhea. [Extracted from the article]

Researchers at Yunnan Agricultural University in China have conducted a study on the porcine epidemic diarrhea virus (PEDV), a highly infectious pathogen that causes disease in pigs and leads to significant economic losses in the pig industry. The study focused on the interaction between the PEDV N protein and host proteins involved in nucleotide metabolic pathways. The researchers found that the second-largest subunit of RNA polymerase II (RPB2) and uridine phosphorylase 1 (UPP1) interacted with the N protein. Overexpression of RPB2 promoted viral replication, while overexpression of UPP1 inhibited viral replication. This research contributes to a better understanding of the pathogenesis and immune escape mechanism of PEDV. [Extracted from the article]

A new study conducted by researchers at Universidad Continental in Peru has examined the temporal-spatial distribution of bovine tuberculosis in Colombia over a 19-year period. The study utilized geographic information systems (GIS) to develop maps characterizing the disease. The research found that there were 5,273 cases of bovine tuberculosis identified in multiple departments of Colombia during the study period, with the number of cases varying each year. The study concludes that GIS is essential for understanding the behavior of zoonotic diseases like bovine tuberculosis and its potential implications for human and animal health. [Extracted from the article]

A recent study conducted at Hashemite University in Jordan explored the potential link between retroviruses and breast cancer. The researchers analyzed breast cancer samples from 103 Jordanian women and breast tissue samples from 25 control patients. They found that Bovine Leukemia Virus (BLV) was detected in 18.4% of the breast cancer samples, while Mouse Mammary Tumor Virus (MMTV) was detected in 6.8%. However, there were no statistically significant associations between the presence of these retroviruses and various clinicopathological variables. The study suggests the need for further research to establish a clearer association and understand the role of retroviruses in breast cancer. [Extracted from the article]

A new study from the College of Natural and Computational Science provides insights into the prevalence and economic impact of bovine fasciolosis, a disease that affects cattle. The study found that the pooled prevalence of fasciolosis among cattle on postmortem examination was 31.77%. The predominant fluke identified was Fasciola hepatica, and the study also detected mixed infections and unidentified immature flukes. The research concluded that the annual economic loss attributed to fasciolosis-associated liver condemnation among cattle was approximately 40,833,983.15 ETB (6,417,847.73 USD). Integrated control methods are needed to address the impact of bovine fasciolosis on animal health and the economy. [Extracted from the article]

A report from the University of Copenhagen in Denmark has estimated the global economic impacts of 12 dairy cattle diseases and health conditions. The study used an economic simulation to estimate the losses caused by these diseases, taking into account factors such as milk yield, fertility, and culling. The research found that the total annual global losses due to these diseases amount to USD 65 billion. The costliest diseases modeled were subclinical ketosis, clinical mastitis, and subclinical mastitis. The economic burden of these diseases varied across countries, with India, the USA, and China experiencing the greatest losses. [Extracted from the article]

A study conducted by Saarland University examined the causes of persistent digestive disorders, such as abdominal pain and diarrhea, in low-resource settings. The researchers used multiplex real-time PCR to test stool samples from symptomatic patients and asymptomatic controls in Cote d'Ivoire, Mali, and Nepal. The study found that the prevalence of pathogens varied between the three countries, with the highest prevalence observed in Mali. The most common pathogens detected were EAEC, Campylobacter spp., Giardia intestinalis, and adenovirus 40/41. The study concluded that while multiplex PCR allowed for comparison between countries, it had low discriminatory accuracy in distinguishing between symptomatic and asymptomatic individuals. [Extracted from the article]

A patent application has been filed for a vector that can produce circular RNA (circRNA) that is translatable and biologically active in eukaryotic cells. The vector consists of various elements connected in a specific sequence, including homology arms, group I intron fragments, protein coding or noncoding regions, and spacer sequences. The vector can be used to extend the duration of protein expression from RNA messages, addressing a limitation of messenger RNA (mRNA) in biological systems. The patent application does not specify any assigned company or institution. [Extracted from the article]

A patent has been issued to the Massachusetts Institute of Technology for a vector that allows the production of circular RNA (circRNA) that is translatable and biologically active inside eukaryotic cells. The vector consists of various elements arranged in a specific sequence, including homology arms, group I intron fragments, protein coding regions, and spacer sequences. The vector can be used to extend the duration of protein expression from full-length RNA messages, addressing a limitation of messenger RNA (mRNA) in biological systems. This patent provides potential applications for therapeutic and engineering purposes. [Extracted from the article]

The patent application titled "Loco-Regional Perfusion Of An Unarrested Beating Heart" proposes a method and system for perfusing drugs in an unarrested beating heart. The method involves positioning catheters in the coronary arteries and coronary sinus to create a closed circuit that isolates the coronary circulation. The drug is perfused through the closed circuit, allowing for targeted and homogenous delivery to the heart tissue. The system includes a pump and a membrane oxygenation device to maintain perfusion and oxygenation. The method aims to reduce the overall dose of the drug, minimize risks and adverse immune responses, and enable dosing for patients with neutralizing antibodies. [Extracted from the article]

A new report discusses research findings on Coxiella burnetii, a bacterium that causes the infectious zoonotic disease known as Q fever. The report focuses on the relationship between C. burnetii infection and reproductive disorders in cattle, including abortion, stillbirth, perinatal mortality, weak calves, retained fetal membranes, metritis/endometritis, and infertility/sub-fertility. The systematic review analyzed 61 eligible studies and found evidence supporting a deleterious role for Q fever in ASPW complex, retained fetal membranes, and infertility/sub-fertility, but the evidence for metritis/endometritis was unclear. The report concludes that further research is needed, particularly involving larger animal populations and more controlled settings, with more precise definitions of reproductive parameters and robust diagnostic methodologies. [Extracted from the article]

A recent study conducted by researchers from Northwest Minzu University in Lanzhou, China, focused on the detection of bovine viral diarrhea virus (BVDV) in cattle. The researchers aimed to develop a more specific and precise detection method for BVDV. They compared three methods: PCR, RT-qPCR, and RT-LAMP, and found that all three methods had excellent specificity for detecting BVDV. However, RT-qPCR showed the highest sensitivity. The study's findings provide technical support for early screening and prevention of BVDV in cattle. [Extracted from the article]

A report from Chiang Mai University in Thailand discusses three cases of double infection with elephant endotheliotropic herpesvirus (EEHV) types 1A and 4 in captive Asian elephants. The first calf, a 4-year-old female, showed signs of lethargy and depression. The second calf, a 6-year-old female, displayed signs of depression and diarrhea and died within 48 hours of treatment. The third calf, a 2-year-old male, died suddenly. Necropsies were performed on the first two elephants, confirming EEHV infection. The study describes the hematological and pathological characteristics of the host following double EEHV infection. [Extracted from the article]

A patent application has been filed for a spike-in reference standard that can be used to detect the presence of the 2019-nCoV (SARS-CoV-2) virus in samples. The reference standard is a recombinant viral particle that contains the same nucleic acid sequence as the target virus and can be used to assess the accuracy of detection and quantify the virus. This invention has potential applications in controlling the spread of the virus, diagnosing and treating the disease, and evaluating the effects of new drugs. The patent application also describes the preparation of qualitative and quantitative reference standard RNA and DNA from the mock virus particle for quality control purposes. [Extracted from the article]

A study conducted at Huazhong Agricultural University in Wuhan, China, investigated the safety and efficacy of an attenuated and marker M. bovis-BoHV-1 combined vaccine in bovines. Bovine respiratory disease (BRD) is a common disease in the cattle industry caused by multiple bacterial or viral coinfections, including Mycoplasma bovis (M. bovis) and bovine herpesvirus type 1 (BoHV-1). The researchers developed a combined vaccine based on previous strains and evaluated its safety and efficacy in cattle. The results showed that the vaccine was clinically safe and protective, with the mix of specific antigen ratios showing the most promising results. This study introduces a potential vaccine for use in the cattle industry. [Extracted from the article]

A recent study conducted by researchers at the Hubei Academy of Agricultural Sciences in Wuhan, China, has identified a highly virulent strain of the Porcine Epidemic Diarrhea Virus (PEDV). The study found that this G2a variant of PEDV caused severe symptoms and high mortality rates in piglets. The researchers believe that this discovery is significant for understanding PEDV in Hubei and could contribute to the development of more effective vaccines. The study has been peer-reviewed and published in the Journal of General Virology. [Extracted from the article]

This article discusses the risks and challenges associated with transmissible spongiform encephalopathies (TSEs), such as Creutzfeldt-Jakob disease (CJD) and its variant form (vCJD). TSEs are rare, fatal brain diseases caused by prion agents that can remain undetected for years. The article highlights the risk of transmitting vCJD through blood transfusions and other biological sources, and the measures taken by the FDA to reduce this risk, such as deferring high-risk individuals from donating blood. The article also discusses ongoing research efforts to develop screening tests for TSE agents in donated blood and to produce reference standards for validating these tests. [Extracted from the article]

Researchers at the Instituto Nacional de Investigaciones Forestales in Mexico have conducted a study comparing the transcriptomes of an attenuated vaccine strain and virulent strains of Babesia bigemina, a protozoan that causes bovine babesiosis. The study aimed to identify the biological mechanisms involved in the attenuation of the vaccine strain. Through transcriptomic analysis, the researchers identified differentially expressed genes and found similarities and differences in cellular components, biological processes, and molecular functions between the two strains. The findings provide insights into the potential molecular mechanisms associated with attenuation or pathogenicity and offer molecular markers that could be associated with virulence or potential vaccine candidates. [Extracted from the article]

A recent study conducted at the University of Indonesia aimed to identify the patterns of pathogens in children with acute diarrhea, both those infected with HIV and those who were not. The study utilized multiplex real-time polymerase chain reaction (RT-PCR) to analyze specimens collected from a tertiary hospital in Jakarta. The results showed that HIV-infected children had a higher rate of positive multiplex RT-PCR results compared to non-HIV-infected children. The study also found that enteropathogens in non-HIV children consisted mainly of bacteria, while in HIV-infected children, viral and parasite infections were more common. The researchers concluded that understanding the pattern of enteropathogens can assist clinicians in determining appropriate treatment for patients. [Extracted from the article]

A study conducted by the Institute of Veterinary Medicine in Innsbruck, Austria, explores the integration of small ruminants (sheep and goats) into the monitoring program for pestiviruses, specifically the border disease virus (BDV). The research highlights the risk of BDV infections in cattle due to contact with small ruminant populations. The study analyzes 23,406 sheep and goat samples and detects BDV-3 in 40 sheep from five different federal states. By including small ruminants in pestivirus monitoring, the introduction of BDV into cattle herds can be significantly minimized in the future. [Extracted from the article]

Researchers from the Anhui Academy of Agricultural Sciences in Hefei, China have conducted a study on porcine epidemic diarrhea (PED), a highly fatal disease in piglets caused by the porcine epidemic diarrhea virus (PEDV). The researchers used a genome-scale CRISPR/Cas9 knockout library to identify key host factors that facilitate PEDV infection. They discovered that knocking out the genes TRIM2 and SLC35A1 inhibited PEDV replication, and also found that a compound called chem-80,048,685 significantly inhibited PEDV attachment and replication. These findings provide new insights into host-pathogen interactions and potential therapeutic targets for PEDV infection. [Extracted from the article]

A study conducted in the Madre de Dios region of Peru aimed to determine the seroprevalence of reproductive and infectious diseases in tropical cattle. The study found a low prevalence of antibodies to certain diseases, but high prevalence to bluetongue virus (BTV), bovine leukemia virus (BLV), and bovine herpes virus-1 (BHV). The presence of BLV and BHV was higher in certain districts and in younger cattle with specific breed characteristics. The researchers concluded that the high prevalence of these diseases may be due to livestock management practices, direct contact with infected animals, and climate change in the tropics. [Extracted from the article]

A recent report from the University of Teramo in Italy discusses research on the Classical Swine Fever Virus (CSFV). The CSFV is a member of the Flaviviridae family and has a significant impact on the pig industry worldwide. While the virus is typically restricted to domestic and wild suids, there have been reports of its presence in bovine species in China and India. The bovine strains of the virus were found to be genetically related to a Chinese CSFV live attenuated vaccine strain used in pigs. These findings highlight the need for further investigation, particularly in countries implementing CSFV control and eradication strategies. [Extracted from the article]

A recent study conducted by the University of South Africa investigated the prevalence of Theileria parva infections in cattle in the corridor disease (CD)-controlled area of KwaZulu-Natal Province. The study found that the overall prevalence of T. parva was low, with rates of 1.3% and 19.9% on quantitative real-time PCR (qPCR) and indirect fluorescent antibody test (IFAT), respectively. The prevalence of T. taurotragi, another type of infection, was higher at 39.4%. The study concluded that the adaptation of buffalo-derived T. parva in cattle populations resulting in cattle-cattle transmissions is unlikely under the current epidemiological state. [Extracted from the article]

A patent application titled "Use of Sugar Cane Extracts in the Treatment or Prevention of Microbial Infections and Dysbiosis" has been published online. The inventors propose the use of sugar cane extracts containing polyphenols to inhibit or inactivate viruses, parasites, and methanogens. The extracts can be administered through various routes and have potential applications in human and animal health. The application also discusses the potential use of sugar cane extracts in mitigating greenhouse gas emissions and improving vaccine immune responses. Detailed claims and compositions for each specific use are provided in the application. [Extracted from the article]

A recent study conducted at the University of Saskatchewan in Canada examined the effects of gastrointestinal nematode (GIN) infection on the antibody response to the bovine viral diarrhea virus (BVDV-1) vaccine in fall-weaned feedlot cattle from western Canada. The study found that GIN infection, as indicated by fecal egg counts and Ostertagia ostertagi serum antibody titers, did not have a significant impact on the humoral immune response to the vaccine antigens. However, further research is needed to investigate the effects of higher GIN burdens and immune protection from clinical disease. This study highlights the importance of understanding regional factors that may affect vaccine response in cattle. [Extracted from the article]

A recent study conducted at the Peter MacCallum Cancer Center in Melbourne, Australia, examined the association between infectious diarrhea and graft-versus-host disease (GVHD) in patients who underwent allogeneic stem cell transplantation. The study found that non-viral pathogens of infectious diarrhea were significantly associated with the development of GVHD. Specifically, bacterial infections, Clostridioides difficile infection (CDI), and multiple infections were independently associated with a higher risk of severe gastrointestinal GVHD. The researchers suggest that further research is needed to investigate whether preventing infectious diarrhea can reduce the incidence of GVHD. [Extracted from the article]

A research report from George Washington University discusses the epidemiology and clinical characteristics of adult astrovirus gastroenteritis in the metropolitan Washington DC area. The study found that the overall positivity rate of astrovirus was 0.6%, with the highest rate in 2018 and none in 2020. Symptoms of astrovirus gastroenteritis included diarrhea, abdominal pain, vomiting, and fever. The study also found that PCR testing can rapidly diagnose viral gastroenteritis and reduce inappropriate antibiotic administration. This is the first case series on adult astrovirus infections in the DC area and provides novel findings different from observations in children. [Extracted from the article]

A study conducted by researchers from the Institute of Animal Science in Prague, Czech Republic, focuses on the genomic evaluation of three common reproductive disorders in Holstein cattle: retained placenta (RP), metritis/endometritis (MET), and cystic ovarian disease (CYS). The researchers proposed a procedure for estimating genetic parameters and genomic breeding values for these disorders. The study found that there is a genetic predisposition to cystic ovarian disease in high-producing cows, and positive correlations were observed between reproductive disorders and other health traits, indicating that improving one health trait could lead to improvements in others. The research provides valuable insights into the genetics of reproductive disorders in Holstein cattle breeding. [Extracted from the article]

A recent study conducted at the Federal University Rural de Pernambuco examined the epidemiological, clinical, and hematological aspects of bovine anaplasmosis. The study analyzed 230 clinical records of cattle from 2012 to 2021 and found that anaplasmosis was the most frequent hemoparasitosis in the region. The disease primarily affected female cattle aged 24 months or younger, with symptoms including apathy, decreased appetite, icteric mucous membranes, and tachycardia. Treatment with antimicrobials and blood transfusion led to clinical improvement in 82.6% of patients, with a mean hospital stay of eight days. The researchers recommend early diagnosis and treatment to minimize the economic impact on the dairy industry in the state of Pernambuco. [Extracted from the article]

A recent study conducted by Purdue University examined the dynamics of the nasopharyngeal microbiome in calves with bovine respiratory disease (BRD) and apparently healthy calves. The researchers found that the microbiome of healthy calves remained consistent throughout the study, while the administration of antibiotics affected the microbiome composition in BRD-affected calves. Interestingly, the relative abundance of BRD-pathobionts differed between individual calves but was not strongly predictive of clinical signs of BRD. The study suggests that additional factors are likely important in the progression of BRD. [Extracted from the article]

A study conducted by researchers at Manicaland State University of Applied Sciences in Mutare, Zimbabwe, explores the challenges faced by smallholder farmers in effectively managing their cattle due to rapid outbreaks of theileriosis and other tick-borne diseases. The study found that these outbreaks result in significant economic losses, posing threats to food security and rural livelihoods. Factors such as the level of education of the household head, access to an animal health officer, training on cattle diseases, and formal credit access were identified as significant variables in reducing economic losses. The researchers recommend increasing the number of animal health officers, strengthening training programs, developing a comprehensive disease-reporting network, and implementing policies that incentivize banks to lend money to farmers to mitigate these losses. [Extracted from the article]

A clinical trial, NCT06122870, is currently underway to assess the effectiveness and safety of CampETEC Hyperimmune Bovine Colostrum (HBC) in preventing Campylobacter-mediated diarrheal diseases. This is particularly important in low- and middle-income countries where gastrointestinal infections cause significant morbidity. The trial aims to evaluate the safety and efficacy of orally administered bovine immunoglobulins in preventing moderate-severe diarrhea caused by Campylobacter C. jejuni strain CG8421. The article also discusses the global burden of diarrheal diseases and the need for preventive measures, such as vaccines, to reduce their impact. Additionally, it mentions the potential development of a capsule conjugate vaccine for Campylobacter jejuni. Another clinical trial, not yet recruiting participants, is investigating the efficacy of a milk immunoglobulin concentrate in preventing illness caused by enterotoxigenic Escherichia coli (ETEC) infection. The trial will enroll 30 healthy adults between the ages of 18 and 50 and is expected to be completed by February 2025. It is being conducted by the Johns Hopkins Bloomberg School of Public Health in collaboration with the Naval Medical Research Center and the United States Department of Defense. [Extracted from the article]

A new study conducted by researchers at the Instituto de Patobiologia in Argentina provides insights into the prevalence, risk factors, and molecular epidemiology of neonatal cryptosporidiosis in calves. Cryptosporidiosis is a parasitic disease caused by enteroparasitic protozoans that affects newborn calves, leading to diarrhea and dehydration. The disease is also zoonotic, meaning it can be fatal for children under five, the elderly, and immunocompromised adults. The study found that Cryptosporidium parvum was the predominant pathogen causing calf diarrhea, and identified nine GP60 subtypes of the pathogen. The research contributes to a better understanding of bovine cryptosporidiosis and can aid in the development of control strategies for this veterinary and medical concern. [Extracted from the article]

A new study conducted by researchers at Jawaharlal Nehru Medical College in Maharashtra, India, has reported a rare case of hypoglycemic encephalopathy in a six-month-old infant following a diagnosis of Coronavirus Disease (COVID-19). The infant presented with fever, diarrhea, and convulsions, and nasal and throat swabs were positive for the SARS-CoV-2 viral antigen. Magnetic Resonance Imaging (MRI) revealed altered signal intensity in the brain, indicating hypoglycemic encephalopathy. The patient was treated with dextrose and saline infusions, and the diagnosis of hypoglycemic encephalopathy secondary to COVID-19 was made. Further information on this research can be found in the Journal of Clinical and Diagnostic Research. [Extracted from the article]

"Prior to this invention, there were three main techniques for making circularized RNA in vitro: the splint-mediated method, the permuted intron-exon method, and the RNA ligase-mediated method. Keywords: Coxsackievirus; Diseases and Conditions; Enterovirus; Genetics; Hepatitis; Liver Diseases and Conditions; Parechovirus; Patent Application; Picornaviridae; RNA Viruses; Rhinovirus; Risk and Prevention; Therapy; Viral; Viral RNA; Virology; Viruses EN Coxsackievirus Diseases and Conditions Enterovirus Genetics Hepatitis Liver Diseases and Conditions Parechovirus Patent Application Picornaviridae RNA Viruses Rhinovirus Risk and Prevention Therapy Viral Viral RNA Virology Viruses 2490 2490 1 11/06/23 20231110 NES 231110 2023 NOV 10 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- A patent application by the inventors Anderson, Daniel G. (Cambridge, MA, US); Fuse, Shinichiro (Cambridge, MA, US); Goodman, Brian (Cambridge, MA, US); Horhota, Allen T. (Cambridge, MA, US); Squilloni, Raffaella (Cambridge, MA, US); Wesselhoeft, Robert Alexander (Cambridge, MA, US), filed on December 21, 2022, was made available online on October 19, 2023, according to news reporting originating from Washington, D.C., by NewsRx correspondents. The pharmaceutical composition of claim 1, wherein the 5' group I intron fragment is a 5' post-splicing group I intron fragment; and the 3' group I intron fragment is a 3' post-splicing group I intron fragment. "In some embodiments, less than 1%, by weight, of the polynucleotides and proteins in the pharmaceutical composition are double stranded RNA, DNA splints, triphosphorylated RNA, phosphatase proteins, protein ligases, and capping enzymes. [Extracted from the article]

Keywords: Bovine Mastitis; Infectious Diseases and Conditions; Zoonotic Diseases EN Bovine Mastitis Infectious Diseases and Conditions Zoonotic Diseases 6259 6259 1 10/30/23 20231103 NES 231103 2023 NOV 3 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators publish new report on zoonotic diseases. Keywords for this news article include: University of Tabriz, Bovine Mastitis, Zoonotic Diseases, Infectious Diseases and Conditions. Bovine Mastitis, Infectious Diseases and Conditions, Zoonotic Diseases. [Extracted from the article]

Keywords for this news article include: University of Cordoba, Cordoba, Spain, Europe, Actinobacteria, Mycobacteriaceae, Gram-Positive Rods, Bovine Tuberculosis, Gram-Positive Bacteria, Mycobacterium Infections, Actinomycetales Infections, Mycobacterium tuberculosis, Gram-Positive Asporogenous Rods. Actinobacteria, Actinomycetales, Actinomycetales Infections, Bovine Tuberculosis, Bovine Tuberculosis, Gram-Positive Asporogenous Rods, Gram-Positive Bacteria, Gram-Positive Rods, Mycobacteria, Mycobacteriaceae, Mycobacterium, Mycobacterium Infections, Mycobacterium tuberculosis, Tuberculosis Keywords: Actinobacteria; Actinomycetales; Actinomycetales Infections; Bovine Tuberculosis; Gram-Positive Asporogenous Rods; Gram-Positive Bacteria; Gram-Positive Rods; Mycobacteria; Mycobacteriaceae; Mycobacterium; Mycobacterium Infections; Mycobacterium tuberculosis; Tuberculosis EN Actinobacteria Actinomycetales Actinomycetales Infections Bovine Tuberculosis Gram-Positive Asporogenous Rods Gram-Positive Bacteria Gram-Positive Rods Mycobacteria Mycobacteriaceae Mycobacterium Mycobacterium Infections Mycobacterium tuberculosis Tuberculosis 5228 5228 1 10/30/23 20231103 NES 231103 2023 NOV 3 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- A new study on Mycobacterium tuberculosis is now available. [Extracted from the article]

Coronaviridae, Coronavirus, Diarrhea, Epidemiology, Health and Medicine, Nidovirales, Porcine Epidemic Diarrhea Virus, RNA Viruses, Vertebrate Viruses Keywords: Coronaviridae; Coronavirus; Diarrhea; Epidemiology; Health and Medicine; Nidovirales; Porcine Epidemic Diarrhea Virus; RNA Viruses; Vertebrate Viruses EN Coronaviridae Coronavirus Diarrhea Epidemiology Health and Medicine Nidovirales Porcine Epidemic Diarrhea Virus RNA Viruses Vertebrate Viruses 1828 1828 1 10/30/23 20231103 NES 231103 2023 NOV 3 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- Investigators discuss new findings in porcine epidemic diarrhea virus. [Extracted from the article]