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2. Intermittent dosing of zoledronic acid based on bone turnover marker assessment reduces vertebral and non-vertebral fractures.

Author

Borgen, Tove Tveitan, Lee-Ødegård, Sindre, Eriksen, Barbara Fink, and Eriksen, Erik Fink

Subjects
VERTEBRAL fractures, BONE density, BONE remodeling, FEMORAL fractures, ZOLEDRONIC acid, TERIPARATIDE, FRACTURE healing
Abstract

Previous studies have demonstrated that the administration of zoledronic acid (ZOL) once yearly for 3 years or once over 3 years, yields similar antifracture efficacy. Bone turnover markers can predict the antifracture efficacy of antiresorptive agents, with procollagen type 1 N-terminal propeptide (P1NP) being the most useful marker. In this retrospective cohort study, we explored the effects of intravenous dosing of ZOL guided by serum (S)-P1NP assessment on bone mineral density (BMD) and fractures. Consenting patients (N  = 202, mean age 68.2 years) with osteoporosis were treated with ZOL for an average of 4.4 (range 2-8) years. S-P1NP and BMD were measured at baseline and every 1-2 years. We assessed the number of subsequent vertebral and nonvertebral fractures in the 2-year time periods. The number of patients assessed was 202, 147, 69, and 29 at years 1-2, 3-4, 5-6, and 7-8, respectively. A new ZOL infusion was given if S-P1NP exhibited values above 35 μg/L. BMD increased by 6.2% (SD 4.0) over the first 2 years and stabilized in years 2-8 (P  <.05). Median S-P1NP exhibited an initial reduction from 58.0 to 31.3 μg/L at year 2 and then increased to 39.0 μg/L at years 7-8. Compared with fractures observed in the last 2 years before baseline, fracture rates exhibited consistent reductions, for vertebral fractures odds ratio (OR) [95% confidence interval] = 0.61 [0.47, 0.80], P  <.001 and for nonvertebral fractures OR = 0.23 [0.18, 0.31], P  <.001. In conclusion, intermittent dosing of intravenous ZOL based on the assessment of S-P1NP with cut-off at 35 μg/L resulted in an initial increase followed by a stable BMD, suppression of S-P1NP, and stable reduction of fractures for 8 years. Only 39% of patients needed more than one infusion. This approach reduces healthcare costs and might also reduce the risk of rare side effects such as osteonecrosis of the jaw and atypical femoral fracture. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Anabolics

Author

Eriksen, Erik Fink, Silverman, Stuart, editor, and Abrahamsen, Bo, editor

Published
2016
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9. Management of Aromatase Inhibitor-Associated Bone Loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: Joint position statement of the IOF, CABS, ECTS, IEG, ESCEO, IMS, and SIOG

Author

Hadji, Peyman, Aapro, Matti S., Body, Jean-Jacques, Gnant, Michael, Brandi, Maria Luisa, Reginster, Jean Yves, Zillikens, M. Carola, Glüer, Claus-C., de Villiers, Tobie, Baber, Rod, Roodman, G. David, Cooper, Cyrus, Langdahl, Bente, Palacios, Santiago, Kanis, John, Al-Daghri, Nasser, Nogues, Xavier, Eriksen, Erik Fink, Kurth, Andreas, Rizzoli, Rene, and Coleman, Robert E.

Published
2017
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16. Disease-Modifying Adjunctive Therapy of Osteopenia and Osteoporosis with a Multimineral Marine Extract, LithoLexal ® Bone.

Author

O'Gorman, Denise M., Naderi, Zahra, Yeganeh, Ali, Malboosbaf, Ramin, and Eriksen, Erik Fink

Subjects
OSTEOPENIA, OSTEOPOROSIS, EXTRACTS, MARINE algae, BONE diseases, TREATMENT effectiveness
Abstract

There is evidence to suggest that restoration of major/rare biominerals by supplementation can produce osteogenic and anti-resorptive effects in humans. LithoLexal® is a natural extract harvested from a marine alga, Lithothamnion sp., with a porous microstructure and multimolecular composition rich in calcium (32% w/w) and magnesium (2.2% w/w) together with ~72 trace bioelements. In vitro, LithoLexal® demonstrated cellular-level osteogenic efficacy through enhancing the maturation and activity of pre-osteoblasts. This extract also expressed the ability to suppress osteoclastogenesis by downregulating the pro-resorptive cytokines TNF-α and IL-1β and the master regulator of inflammation NF-κB. Parathyroid hormone inhibition of parathyroid hormone secretion is another bioactivity of LithoLexal® Bone reported with both short- and long-term administration at a longer duration and higher magnitude than what calcium carbonate could induce. Due to these bioactivities that affect pathogenetic factors of osteoporosis, LithoLexal® Bone is referred to as a disease-modifying adjunctive therapy (DMAT). In postmenopausal animal models, LithoLexal® monotherapy preserved bone mineral density, microarchitecture, and biomechanical properties, while calcium carbonate failed to produce significant outcomes. The pro-resorptive effect of a high-fat diet was also efficiently counteracted in vivo by supplementary LithoLexal®. A large clinical trial on postmenopausal women verified the mitigating effects of LithoLexal® Bone on bone resorption and turnover rate. The characteristic composition of LithoLexal® together with its lattice microstructure are suggested to underlie its in vivo bioactivities. In conclusion, adjunctive therapy with LithoLexal® Bone is an attractive option for clinical prevention and treatment of osteopenia/osteoporosis. [ABSTRACT FROM AUTHOR]

Published
2023
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21. Effect of Liothyronine Treatment on Dermal Temperature and Activation of Brown Adipose Tissue in Female Hypothyroid Patients: A Randomized Crossover Study

Author

Bjerkreim, Betty Ann, primary, Hammerstad, Sara Salehi, additional, Gulseth, Hanne Løvdal, additional, Berg, Tore Julsrud, additional, Lee-Ødegård, Sindre, additional, Rangberg, Anbjørg, additional, Jonassen, Christine Monceyron, additional, Budge, Helen, additional, Morris, David, additional, Law, James, additional, Symonds, Michael, additional, and Eriksen, Erik Fink, additional

Published
2021
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30. Determinants of trabecular bone score and prevalent vertebral

Author

Borgen, Tove Tveitan, Bjørnerem, Åshild, Solberg, Lene Bergendal, Andreasen, Camilla, Brunborg, Cathrine, Stenbro, May-Britt, Hübschle, Lars Michael, Figved, Wender, Apalset, Ellen Margrete, Gjertsen, Jan Erik, Basso, Trude, Lund, Ida, Hansen, Ann Kristin, Stutzer, Jens-Meinhard, Dahl, Cecilie, Nordsletten, Lars, Frihagen, Frede Jon, and Eriksen, Erik Fink

Abstract

Summary Determinants of trabecular bone score (TBS) and vertebral fractures assessed semiquantitatively (SQ1–SQ3) were studied in 496 women with fragility fractures. TBS was associated with age, parental hip fracture, alcohol intake and BMD, not SQ1–SQ3 fractures. SQ1–SQ3 fractures were associated with age, prior fractures, and lumbar spine BMD, but not TBS. Introduction Trabecular bone score (TBS) and vertebral fractures assessed by semiquantitative method (SQ1–SQ3) seem to reflect different aspects of bone strength. We therefore sought to explore the determinants of and the associations between TBS and SQ1–SQ3 fractures. Methods This cross-sectional sub-study of the Norwegian Capture the Fracture Initiative included 496 women aged ≥ 50 years with fragility fractures. All responded to a questionnaire about risk factors for fracture, had bone mineral density (BMD) of femoral neck and/or lumbar spine assessed, TBS calculated, and 423 had SQ1–SQ3 fracture assessed. Results Mean (SD) age was 65.6 years (8.6), mean TBS 1.27 (0.10), and 33.3% exhibited SQ1–SQ3 fractures. In multiple variable analysis, higher age (βper SD = − 0.26, 95% CI: − 0.36,− 0.15), parental hip fracture (β = − 0.29, 95% CI: − 0.54,− 0.05), and daily alcohol intake (β = − 0.43, 95% CI − 0.79, − 0.08) were associated with lower TBS. Higher BMD of femoral neck (βper SD = 0.34, 95% CI 0.25–0.43) and lumbar spine (βper SD = 0.40, 95% CI 0.31–0.48) were associated with higher TBS. In multivariable logistic regression analyses, age (ORper SD = 1.94, 95% CI 1.51–2.46) and prior fragility fractures (OR = 1.71, 95% CI 1.09–2.71) were positively associated with SQ1–SQ3 fractures, while lumbar spine BMD (ORper SD = 0.75 95% CI 0.60–0.95) was negatively associated with SQ1–SQ3 fractures. No association between TBS and SQ1–SQ3 fractures was found. Conclusion Since TBS and SQ1–SQ3 fractures were not associated, they may act as independent risk factors, justifying the use of both in post-fracture risk assessment.

Published
2020

32. Zoledronic acid and clinical fractures and mortality after hip fracture

Author

Lyles, Kenneth W., Colon-Emeric, Cathleen S., Magaziner, Jay S., Adachi, Jonathan D., Pieper, Carl F., Mautalen, Carlos, Hyldstrup, Lars, Recknor, Chris, Nordsletten, Lars, Moore, Kathy A., Lavecchia, Catherine, Jie Zhang, Mesenbrink, Peter, Hodgson, Patricia K., Abrams, Ken, Orloff, John J., Horowitz, Zebulun, Eriksen, Erik Fink, and Boonen, Steven

Subjects
Zoledronic acid -- Patient outcomes, Zoledronic acid -- Research, Hip joint -- Fractures, Hip joint -- Drug therapy, Hip joint -- Care and treatment, Hip joint -- Prevention
Abstract

The effectiveness of zoledronic acid in prevention of new clinical fractures, to patients undergone hip fracture surgery is studied. Results concluded yearly infusion of zoledronic acid within 90 days of hip fracture surgery reduced risk of new clinical fractures raising survival rate.

Published
2007

33. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis

Author

Black, Dennis M., Delmas, Pierre D., Eastell, Richard, Reid, Ian R., Boonen, Steven, Cauley, Jane A., Cosman, P.H. Felicia, Lakatos, Peter, Ping Chung Leung, Man, Zulema, Mautalen, Carlos, Mesenbrink, Peter, Huilin Hi, Caminis, John, Tong, Karen, Rosario-Jansen, Theresa, Krasnow, Joel, Hue, Trisha F., Sellmeyer, Deborah, Eriksen, Erik Fink, and Cummings, Steven R.

Subjects
Osteoporosis -- Drug therapy, Postmenopausal women -- Health aspects, Zoledronic acid -- Dosage and administration, Zoledronic acid -- Complications and side effects
Abstract

The effects of annual infusion of zoledronic acid in postmenopausal women are assessed. This dose was found to improve the bone density and reduce the risk of osteoporotic fractures over a period of three years.

Published
2007

40. Contributors

Author

Adler, Robert A., primary, Allen, Matthew R., additional, Amin, Shreyasee, additional, Antoniucci, Diana M., additional, Araujo, Andre B., additional, Armas, Laura A.G., additional, Baroncelli, Giampiero I., additional, Bertelloni, Silvano, additional, Bhasin, Shalender, additional, Bilezikian, John P., additional, Binkley, Neil C., additional, Boonen, Steven, additional, Boskey, Adele L., additional, Bouillon, Roger, additional, Burr, David B., additional, Burrows, Melonie, additional, Callewaert, Filip, additional, Carmeliet, Geert, additional, Cianferotti, Luisella, additional, Compston, Juliet, additional, Cosman, Felicia, additional, Cremers, Serge, additional, Davison, K. Shawn, additional, Dempster, David W., additional, Eisman, John A., additional, Fuleihan, Ghada El-Hajj, additional, Eriksen, Erik Fink, additional, Favus, Murray J., additional, Felsenberg, Dieter, additional, Ferrari, Serge, additional, Fyhrie, David P., additional, Garnero, Patrick, additional, Gennari, Luigi, additional, Geusens, Piet, additional, Gilsanz, Vicente, additional, Girotra, Monica, additional, Giusti, Andrea, additional, Giustina, Andrea, additional, Goemaere, Stefan, additional, Gold, Deborah T., additional, Guo, X. Edward, additional, Haentjens, Patrick, additional, Halse, Johan, additional, Handelsman, David J., additional, Haney, Elizabeth M., additional, Hanley, David A., additional, Heaney, Robert P., additional, Jasuja, Ravi, additional, Johansson, Helena, additional, Kanis, John A., additional, Kaufman, Jean-Marc, additional, Klein, Robert, additional, Kousteni, Stavroula, additional, Krueger, Diane, additional, Lakshman, Kishore M., additional, Lang, Thomas F., additional, Lapauw, Bruno, additional, Lappe, Joan M., additional, Leder, Benjamin Z., additional, Lems, Willem, additional, Liu, X. Sherry, additional, Lu, Shi S., additional, Macdonald, Heather M., additional, Maes, Christa, additional, Maloney, Ann E, additional, Cawthon, Peggy Mannen, additional, Marcocci, Claudio, additional, Marshall, Lynn, additional, Mazziotti, Gherardo, additional, McCloskey, Eugene V., additional, McKay, Heather A., additional, Meier, Christian, additional, Miller, Paul D., additional, Misra, Bismruta, additional, Mora, Stefano, additional, Nguyen, Tuan V., additional, Oden, Anders, additional, Ohlsson, Claes, additional, O’Neill, Terence W., additional, Orwoll, Eric S., additional, Papapoulos, Socrates E., additional, Rizzoli, René, additional, Rosen, Clifford J., additional, Runge, Martin, additional, Schousboe, John T., additional, Seeman, Ego, additional, Seibel, Markus J., additional, Sellmeyer, Deborah E., additional, Shane, Elizabeth, additional, Shapiro, Jay R., additional, Silverberg, Shonni J., additional, Silverman, Stuart L., additional, Singh, Rajan, additional, Stein, Emily M., additional, Storer, Thomas W., additional, Szulc, Pawel, additional, Tabbal, Mahmoud, additional, Taes, Youri, additional, Turner, Charles H., additional, Vandenput, Liesbeth, additional, Vanderschueren, Dirk, additional, Venken, Katrien, additional, Verlinden, Lieve, additional, Verstuyf, Annemieke, additional, Wang, Qingju, additional, Weaver, Connie M., additional, Wehrli, Felix W., additional, Wimalawansa, Sunil J., additional, Wiren, Kristine M., additional, Zebaze, Roger, additional, and Zhou, Hua, additional

Published
2010
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43. Contributors

Author

Åkesson, Kristina, primary, Alatalo, Sari L., additional, Allison, Susan J., additional, Aly, Ziyad Al, additional, Baldock, Paul A., additional, Bilezikian, John P., additional, Binkley, Neil, additional, Body, Jean-Jacques, additional, Bonjour, Jean-Philippe, additional, Boskey, Adele L., additional, Bouillon, Roger, additional, Brixen, Kim, additional, Bruckner, Peter, additional, Carmeliet, Geert, additional, Clark, Ian M, additional, Croucher, Peter, additional, Delmas, Pierre D., additional, Dempster, David W., additional, Devogelaer, Jean-Pierre, additional, Drezner, Marc K., additional, Eastell, Richard, additional, Eelen, Guy, additional, Eriksen, Erik Fink, additional, Fitzpatrick, Lorraine A., additional, Fuleihan, Ghada El-Hajj, additional, Gardiner, Edith M., additional, Garnero, Patrick, additional, Gay, Renate E., additional, Gay, Steffen, additional, Glorieux, Francis H., additional, Goldring, Mary B., additional, Goldring, Steven R., additional, Goltzman, David, additional, González, Esther A., additional, Grauer, Andreas, additional, Gundberg, Caren M., additional, Hardingham, Tim, additional, Harrison, John R., additional, Heinegård, Dick, additional, Helfrich, M.H., additional, Herzog, Herbert, additional, Horton, M.A., additional, Hulley, Philippa, additional, Jüppner, Harald, additional, Kaija, Helena, additional, Khosla, S., additional, Kraenzlin, Marius E., additional, Kream, Barbara E., additional, Kulak, Carolina A. Moreira, additional, van Leeuwen, Johannes P.T.M., additional, Lensmeyer, Gary L., additional, Lian, Jane B., additional, Lorenzo, Joseph A., additional, Lorenzo, Pilar, additional, Maes, Christa, additional, Manicourt, Daniel-Henri, additional, von der Mark, Klaus, additional, Martin, Kevin J., additional, Martin, T. John, additional, Meier, Christian, additional, van Meurs, Joyce B.J., additional, Millán, José Luis, additional, Monroe, David G., additional, Mulder, Jean E., additional, Murphy, Gillian, additional, Naylor, Kim E., additional, Neidhart, Michel, additional, Nguyen, Tuan V., additional, Nishimoto, Satoru K., additional, Patrikainen, Lila O.T., additional, Pols, Huibert A.P., additional, Raisz, Lawrence G., additional, Ralston, Stuart, additional, Rauch, Frank, additional, Reid, Ian R., additional, Risteli, Juha, additional, Risteli, Leila, additional, Rivadeneira, Fernando, additional, Rizzoli, René, additional, Robins, Simon P., additional, Rosen, Clifford J., additional, Rubin, Mishaela R., additional, Russell, Graham, additional, Saxne, Tore, additional, Schmidt-Gayk, Heinrich, additional, Seeman, Ego, additional, Seibel, Markus J., additional, Shane, Elizabeth, additional, Silverberg, Shonni J., additional, Simkin, Peter A., additional, Sims, Natalie A., additional, Siris, Ethel, additional, Spelsberg, Thomas C., additional, Stein, Gary S., additional, Thonar, Eugene J.-M. A., additional, Uitterlinden, André G., additional, Väänänen, H. Kalervo, additional, Verstuyf, Annemieke, additional, Vihko, Pirkko T., additional, Whyte, Michael P., additional, and Zhou, Hua, additional

Published
2006
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44. Presence of pyrophosphate in bone from an atypical femoral fracture site: A case report

Author

Shabestari, Maziar, Eriksen, Erik Fink, Paschalis, Eleftherios P., Roschger, Paul, Gamsjaeger, Sonja, Klaushofer, Klaus, Berzlanovich, Andrea, Nogués Solán, Xavier, Puig, Lluis, Díez Pérez, Adolfo, and Universitat Autònoma de Barcelona

Subjects
0301 basic medicine, Pathology, medicine.medical_specialty, Pyrophosphate, lcsh:Diseases of the musculoskeletal system, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Case Report, Pathogenesis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Atypical femoral fracture, Osteoclastic resorption, Medicine, Orthopedics and Sports Medicine, Impaired mineralization, business.industry, Histology, Backscattered electron, Surgery, 030104 developmental biology, Denosumab, chemistry, lcsh:RC925-935, business, Fractures, medicine.drug
Abstract

Altres ajuts: The present study was supported by the Allgemeine Unfallversicherungsanstalt (AUVA), research funds of the Austrian workers compensation board, and the Wiener Gebietskrankenkasse (WGKK), Viennese sickness insurance funds. Long-term antiresorptives use has been linked to atypical subtrochanteric and diaphyseal femoral fractures (AFF), the pathogenesis of which is still unknown. In the present case report we present the results of analysis of bone chips from a 74-year old female patient that had been on alendronate, ibandronate and denosumab treatment, and who sustained an atypical femoral fracture, by histology, quantitative backscattered electron imaging, and Raman spectroscopic analysis. The results indicate ongoing osteoclastic resorption, but also several abnormalities: 1) an altered arrangement of osteons; 2) impaired mineralization; 3) the presence of pyrophosphate, which might contribute to the impaired mineralization evident in the present case. Taken together, these changes may contribute to the focally reduced bone strength of this patient.

Published
2017
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45. List of Contributors

Author

Abrams, Steven A., primary, Adams, John S., additional, Adams, Judith E., additional, Adorini, Luciano, additional, Anderson, Paul H., additional, Atkins, Gerald J., additional, Aubin, Jane E., additional, Bailleul-Forestier, Isabelle, additional, Barsony, Julia, additional, Barthel, Thomas K., additional, Bell, Norman H., additional, Berdal, Ariane, additional, Bergh, Joel J., additional, Berry, Jacqueline L., additional, Bikle, Daniel D., additional, Bilezikian, John P., additional, Binderup, Ernst, additional, Binderup, Lise, additional, Bishop, Nicholas J., additional, Bogaerts, Ilse, additional, Boland, Ricardo L., additional, Boskey, Adele L., additional, Bouillon, Roger, additional, Boyan, Barbara D., additional, Brachet, Philippe, additional, Brown, Alex J., additional, Brown, Edward M., additional, Carlberg, Carsten, additional, Carmeliet, Geert, additional, Carpenter, Thomas O., additional, Chapuy, Marie-Claire, additional, Chan, Fredriech K.W., additional, Chen, Tai C., additional, Christakos, Sylvia, additional, Clagett-Dame, Margaret, additional, Clemens, Thomas L., additional, Choi, Je-Yong, additional, Coe, Fredric L., additional, Colston, Kay, additional, Compston, Juliet E., additional, Cooke, Nancy E., additional, Crescioli, Clara, additional, Cross, Heide S., additional, Danilenko, Michael, additional, Davideau, Jean-Luc, additional, Davies, Michael, additional, DeLuca, Hector F., additional, Demay, Marie B., additional, Dhawan, Puneet, additional, Dominguez, Carlos Encinas, additional, Dowd, Diane R., additional, Drezner, Marc K., additional, Dunlop, Thomas W., additional, Dusso, Adriana S., additional, Eastell, Richard, additional, Econs, Michael J., additional, Eisman, John, additional, Epstein, Sol, additional, Eriksen, Erik Fink, additional, Esteban, Luis M., additional, Faibish, Dan, additional, Fang, Yue, additional, Farach-Carson, Mary C., additional, Favus, Murray J., additional, Feldman, David, additional, Findlay, David, additional, Frank, Christian, additional, Freedman, Leonard P., additional, Fujiki, Ryuji, additional, Fukagawa, Masafumi, additional, Gagel, Robert F., additional, Garcion, Emmanuel, additional, Gardiner, Edith M., additional, Gascon-Barré, Marielle, additional, Giovannucci, Edward, additional, Glerup, Henning, additional, Glorieux, Francis H., additional, Godtfredsen, Wagn O., additional, Goltzman, David, additional, Gutierrez, Soraya, additional, Gysemans, Conny, additional, Halloran, Bernard P., additional, Haussler, Carol A., additional, Haussler, Mark R., additional, Heaney, Robert P., additional, Heersche, Johan, additional, Henry, Helen L., additional, Hershberger, Pamela A., additional, Hewison, Martin, additional, Heyman, Richard A., additional, Higashio, Kanji, additional, Holick, Michael F., additional, Hollis, Bruce W., additional, Horst, Ronald L., additional, Hsieh, Jui-Cheng, additional, Insogna, Karl L., additional, Jacobs, Elizabeth T., additional, Javed, Amjad, additional, Jones, Glenville, additional, Johnson, Candace S., additional, Jurutka, Peter W., additional, Kahraman, Mehmet, additional, Zaidi, S. Kaleem, additional, Kalkwarf, Heidi J., additional, Kato, Shigeaki, additional, Kissmeyer, Anne-Marie, additional, Kitagawa, Hirochika, additional, Koberle, Lilia M.C., additional, Koeffler, H. Phillip, additional, Koren, Ruth, additional, Kream, Barbara E., additional, Kremer, Richard, additional, Krishnan, Aruna V., additional, Kubodera, Noboru, additional, Kumar, Rajiv, additional, Kurokawa, Kiyoshi, additional, Laing, Christopher J., additional, Lemire, Jacques, additional, Lézot, Frédéric, additional, Li, Yan Chun, additional, Lian, Jane B., additional, Lichtler, Alexander C., additional, Lips, Paul, additional, Liu, Yan, additional, MacDonald, Paul, additional, Maehr, Hubert, additional, Maggi, Mario, additional, Malloy, Peter J., additional, Mangelsdorf, David J., additional, Mathieu, Chantal, additional, May, Brian, additional, Mee, Andrew P., additional, Meunier, Pierre J., additional, Michigami, Toshimi, additional, Montecino, Martin, additional, Moras, Dino, additional, Morosetti, Roberta, additional, Morris, Howard A., additional, Motola, Daniel L., additional, Muindi, Josephia, additional, Nakajima, Shigeo, additional, Naveh-Many, Tally, additional, Naveilhan, Philippe, additional, Neveu, Isabelle, additional, Norman, Anthony W., additional, Nykjaer, Anders, additional, O'Kelly, James, additional, Omdahl, John L., additional, Ordentlich, Peter, additional, Ozono, Keiichi, additional, Parfitt, A. Michael, additional, Peehl, Donna M., additional, Peleg, Sara, additional, Peng, Xiaorong, additional, Pettifor, John M., additional, Pike, J. Wesley, additional, Platz, Elizabeth A., additional, Plum, Lori A., additional, Pockwinse, Shirwin, additional, Pols, Huibert A.P., additional, Portale, Anthony A., additional, Posner, Gary H., additional, Rahmaniyan, Mehrdad, additional, Ravid, Amiram, additional, Reddy, G. Satyanarayana, additional, Reichrath, Jörg, additional, Reinhardt, Timothy A., additional, Reszka, Alfred A., additional, Riggs, B. Lawrence, additional, Rochel, Natacha, additional, Rubin, Mishaela R., additional, Russo, Andrew F., additional, Sambrook, Philip, additional, Schneider, Adina E., additional, Schwartz, Gary G., additional, Schwartz, Zvi, additional, Shen, Jiali, additional, Shevde, Nirupama K., additional, Sicinski, Rafal R., additional, Silver, Justin, additional, Slatopolsky, Eduardo A., additional, Specker, Bonny L., additional, St-Arnaud, René, additional, Stein, Gary S., additional, Stein, Janet L., additional, Stern, Paula H., additional, Studzinski, George P., additional, Suda, Tatsuo, additional, Sutton, Amelia L.M., additional, Tebben, Peter, additional, Tenenhouse, Harriet S., additional, Thatcher, Michelle L., additional, Thys-Jacobs, Susan, additional, Towler, Dwight A., additional, Trump, Donald L., additional, Uitterlinden, André G., additional, Uskoković, Milan R., additional, Väisänen, Sami, additional, Van Baelen, Hugo, additional, Van Cromphaut, Sophie, additional, van Leeuwen, Johannes P.T.M., additional, van Meurs, Joyce B.J., additional, van Wijnen, Andre J., additional, Verboven, Christel, additional, Vieth, Reinhold, additional, Wasserman, Robert H., additional, Welsh, JoEllen, additional, Whitfield, G. Kerr, additional, Whyte, Michael P., additional, Willnow, Thomas, additional, Wion, Didier, additional, Yasuda, Hisataka, additional, Young, Daniel, additional, and Zhang, Chi, additional

Published
2005
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48. In memoriam:Leif Mosekilde

Author

Rejnmark, Lars, Brixen, Kim, Kassem, Moustapha, Hermann, Pernille, Vestergaard, Peter, Eriksen, Erik Fink, Bollerslev, Jens, Nielsen, Henning K, Charles, Peder, and Langdahl, Bente

Published
2018

49. Leif Mosekilde IN MEMORIAM

Author

Rejnmark, Lars, Brixen, Kim, Kassem, Moustapha, Hermann, Pernille, Vestergaard, Peter, Eriksen, Erik Fink, Bollerslev, Jens, Nielsen, Henning K., Charles, Peder, and Langdahl, Bente

Published
2018

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