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This article, published in the journal Endoscopy, examines the clinical course of intraprocedural perforation during gastric and colorectal endoscopic submucosal dissection (ESD). The study analyzed 43 cases of perforation out of a total of 3251 ESD procedures performed between 2021 and 2023. The researchers categorized the cases into two groups based on the presence or absence of symptoms and found that the time required for closure of the perforation affected the appearance of postoperative symptoms. The study emphasizes the importance of promptly closing the perforation site for a good clinical outcome. [Extracted from the article]

This article discusses a study conducted to evaluate the efficacy and durability of a transparent silicon attachment called the Static Electricity Fastening Tape (SET) hood, which can be used during colonoscopies. The study involved 69 colonoscopies using the SET hood, and the results showed a 100% completion rate of colonoscopy without hood detachment and a 100% cecal intubation rate. The median intubation time was 8 minutes, and the total examination time had a median of 20 minutes. The adenoma detection rate was 48%, and there were no complications reported. The study concludes that the SET hood is durable and efficient for assisting colonoscopies. [Extracted from the article]

This article discusses the feasibility and technical aspects of endoscopic resection of ileal lipomas, which are benign gastrointestinal subepithelial lesions. The narrow lumen, thin wall, and abundant mucosal blood supply of the small intestines make this area difficult to treat endoscopically. The authors present a novel technique called the "tongue out technique," which involves extracting the lesion into the caecum to provide a better view and workspace. The study analyzed seven cases of endoscopic resection using this technique and found a 100% technical success rate with no perforations or recurrence of the lipoma. The authors conclude that this new technique can facilitate the treatment of ileal lipomas with minimally invasive and organ-preserving endoscopic procedures. [Extracted from the article]

The article discusses the feasibility of a new technique called the Clip with Line Pulley Securing (CLiPS) for closing mucosal defects after gastric endoscopic submucosal dissection (ESD). The study involved 34 patients who underwent gastric ESD and found that the CLiPS technique had a 100% success rate and complete closure rate. The procedure was performed without any complications, and there were no cases of delayed bleeding or perforation. The authors suggest that further validation of the CLiPS technique in other organs is planned for the future. [Extracted from the article]

Thus, the sole manifestation of AIGA as irAE might be overlooked in other patients as anhidrosis rarely causes skin manifestations and patients may not consider it a disease that requires treatment. Recent studies revealed that 60%-100% of patients with AIGA had elevation of serum CEA level, and that this correlates with disease activity.6 Detection of AIGA in our case was helped by repetitive CEA measurements because of the patient's colorectal malignancy. Acquired idiopathic generalized anhidrosis (AIGA) causes a type of heat intolerance that can be life-threatening but is often overlooked.1 We report a patient who developed AIGA possibly as an immune-related adverse event (irAE) of pembrolizumab. [Extracted from the article]

This paper presents a human-centered modeling framework of urban systems to capture various types of interdependency underlying urban sociotechnical and socioeconomic systems. The proposed framework consists of three major subsystems: civil life, manufacturing/service industry, and lifeline infrastructure. This framework classifies nine different types of interdependencies existing within and between these three subsystems. This paper also presents a computer simulation of the post-disaster recovery process of urban systems considering various interdependencies captured by the modeling framework. We adopt an agent-based model incorporating a network model for implementing the three subsystems as well as the various types of interdependencies. A sensitivity analysis was conducted based on the R4 framework of disaster resilience to verify and validate the simulation model. The simulation results were generally consistent with the predictions made by the R4 framework, suggesting that the model was implemented properly and can capture the multiple interdependencies behind the urban systems. [ABSTRACT FROM AUTHOR]

Information systems are a kind of service systems and they are throughout every element of a modern industrial and business system, much like blood in our body. Types of information systems are heterogeneous because of extreme uncertainty in changes in modern industrial and business systems. To effectively manage information systems, modelling of the work domain (or domain) of information systems is necessary. In this paper, a domain modelling framework for the service system is proposed and its application to the enterprise information system is outlined. The framework is defined based on application of a general domain modelling tool called function-context-behaviour-principle-state-structure (FCBPSS). The FCBPSS is based on a set of core concepts, namely: function, context, behaviour, principle, state and structure and system decomposition. Different from many other applications of FCBPSS in systems engineering, the FCBPSS is applied to both infrastructure and substance systems, which is novel and effective to modelling of service systems including enterprise information systems. It is to be noted that domain modelling of systems (e.g. enterprise information systems) is a key to integration of heterogeneous systems and to coping with unanticipated situations facing to systems. [ABSTRACT FROM AUTHOR]