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Copyright of Journal of Harbin Institute of Technology. Social Sciences Edition / Haerbin Gongye Daxue Xuebao. Shehui Kexue Ban is the property of Harbin Institute of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective A Mendelian randomization approach was used to assess the potential causal relationship between gastrointestinal microorganisms and the risk of facial ageing. Methods From December 2023 to March 2024, Genome-wide association analysis (GWAS) meta-data of 196 bacterial taxa (9 phylums, 20 orders, 16 classes, 35 families, and 131 genera) using the MiBioGen consortium of intestinal flora were included in the analysis. Inverse variance weighting, MR-Egger regression, and weighted median method were used to investigate the causal relationship between gut flora and facial aging. Sensitivity analysis was used to test the reliability of the results of Mendelian randomization analysis. Results For facial skin aging, IVW initially identified 10 taxa with potential causal effects on facial skin aging. Genus Parasutterella is negatively associated with facial skin aging. Phylum. Verrucomicrobia, Family. Lactobacillaceae, Genus. Butyricimonas, Genus. Eggerthella, Genus.Family XIII UCG001, Genus. Lactobacillus, Genus. Parabacteroides, Genus. Phascolarctobacterium, Genus Ruminococcaceae UCG005 are positively associated with facial skin aging. Conclusion For facial skin aging, IVW initially identified 10 taxa with potential causal effects on facial skin aging. [ABSTRACT FROM AUTHOR]

The thermal aging process of polyimide is simulated by reactive molecular dynamics method to simulate the property changes of plasma-modified polyimide materials after thermal cracking. By studying the generation of gas during aging, it was found that as the temperature increases, the interaction forces between molecular chains weaken, resulting in a decrease in the denseness of the material, a decrease in the modulus of elasticity, and a decrease in the ability of the material to resist external stress. At the same time, the relative dielectric constant of the polyimide material increases due to the increase of temperature, and the insulation property of the material decreases and the breakdown strength is also weakened. [ABSTRACT FROM AUTHOR]

In order to study the molecular weight and molecular structure changes of asphalt under ultraviolet aging and the mechanism of their effects on macro properties, gel permeation chromatography and nuclear magnetic resonance tests were carried out on four commonly used asphalt, respectively. The molecular weight composition changes, such as molecular weight and molecular relative mass distribution, and the molecular structure composition changes, such as hydrogen spectrum, carbon spectrum, hydrogen atom content and molecular structure parameters were studied. On the basis of macroscopic rheological tests, the molecular composition of asphalt rheological properties was characterized by correlation analysis, and the molecular mechanism of ultraviolet aging macroscopic properties was analyzed. The results show that ultraviolet aging causes the agglomeration of molecules in asphalt, small molecules decreases and aggregates into large molecules, and the molecular weight distribution boundary narrows gradually. From the changes of hydrogen atoms and molecular structure parameters, it can be seen that the alkyl substituents on the aromatic ring in the asphalt increase after ultraviolet aging, resulting in the increase of the volume and stability of the aromatic ring, and the increase of molecular backbone stiffness. On the macro level, the elastic properties of asphalt increase. The phase angle, rutting factor, irrecoverable compliance and recovery rate of asphalt before and after ultraviolet aging were obtained by macroscopic rheological tests. The correlation analysis shows that the rheological properties are most affected by condensation degree parameters, substitution rate of peripheral hydrogen, average molecular weight and branched degree of alkyl chain. [ABSTRACT FROM AUTHOR]

過去研究顯示，高齡者參與學習之社會接觸動機可提升其參與、健康及安全三個層面的活躍老化程度，然而，究竟是什麼機制存在於高齡者的社會接觸動機與活躍老化之間，仍為目前重要卻尚未探討驗證的議題。因此，本研究提出高齡者之「老化態度」為兩者之中介變項，旨在探討高齡者之老化態度能否對參與學習之社會接觸動機與活躍老化之關係有中介效果。本研究使用問卷調查法蒐集資料，研究對象為北部年滿55歲以上高齡者，共回收231份有效問卷，年齡介於55～83歲之間，平均數為62.87歲，男性63位（27.3%），女性168位（72.7%），調查所得資料以結構方程模型（Structural Equation Modeling, SEM）中之Bootstrap統計方法進行中介模式分析。研究結果顯示：一、老化態度中的生理改變態度能中介參與學習之社會接觸動機與活躍老化之間關係；二、老化態度中的正向老化態度能中介參與學習之社會接觸動機與活躍老化中健康與安全層面之間的關係。本研究建議若能提升高齡者在參與學習時的社 會接觸動機，將能改善高齡者的老化態度，進而提升高齡者各層面的活躍老化。 1. Introduction In our aging society, older adult learning is increasingly valued. Learning allows older adults to adapt to changes brought about by aging, to enhance self-confidence, and to face new challenges. Research has shown that social contact motivation in learning is associated with active aging and improved health and security. However, the mechanism through which the social contact motivation of older adults influences active aging requires further research. Past studies stress the importance of older adults understanding their attitudes toward the aging process. Older adults who report a more positive attitude toward aging exhibit increased participation in health promotion behaviors, which in turn allows older adults to truly practice the concept of active aging. Therefore, this study aimed to investigate the mediating effect of attitude toward aging among older adults on social contact motivation in learning and on active aging. 2. Methods Older adults (older than 55 years) in northern Taiwan were recruited. A total of 101 valid questionnaires were collected from the pretest. The age of the respondents ranged from 55 to 81 years; the mean age was 61.58 years. Furthermore, 17 respondents were male (16.8%) and 84 respondents were female (83.2%). In the study proper, a total of 231 valid questionnaires were collected. The age ranged from 55-83 years; the mean age was 62.87 years. In addition, 63 respondents were male (27.3%) and 168 respondents were female (72.7%). Three scales were used: the first measured social contact motivation, which was adapted from the adult learning motivation scale (Kim & Merriam, 2004); the second measured attitude toward aging (Shenkin et al., 2014); and the third measured active aging (Lin, 2012). Social contact motivation refers to contact with friends and making new friends as motivation for learning. The aging attitude scale was developed by Shenkin et al. (2014) in cooperation with the World Health Organization; it measures both positive and negative attitudes toward aging. The active aging scale was developed by Lin (2012). The scale has three dimensions: health, participation, and security. In the pretest, exploratory factor analysis and internal consistency analysis were conducted, and items in the pretest questionnaire were deleted and revised to develop a formal questionnaire. All scales were demonstrated to be valid in a factor analysis, and an overall Cronbach’s alpha of 0.74-0.86 indicated reliability. Structural equation modeling (SEM) with bootstrapping was used for the analysis. 3. Results Correlation analysis indicated that scores for social contact motivation, active aging, and attitudes toward aging were all significantly correlated. Mediating effects were then investigated through SEM. The model had good fit (χ2⁄df = 3.16, p = 0.00, goodness of fit index = 0.89, adjusted goodness of fit index = 0.86, and root mean square error of approximation = 0.07). Therefore, the model was credible and stable. This study calculated the 95% confidence interval and used 2000 repeated samples. The model had “physiological change attitude” and “positive aging attitude” as variables mediating the relationship between social contact motivation and active aging. The SEM results are displayed as follows: 3.1 Direct Effects and Mediating Effects Social contact motivation had a direct relationship with all three dimensions of active aging: health (r = 0.69, p < .05), participation (r = 0.79, p < .05), and security (r = 0.73, p < .05). Potential mediating effects were then examined. Physiological change attitude fully mediated the relationships of social contact motivation with two of the three dimensions of active aging, specifically health (r = 0.17, p < .05) and participation (r = 0.18, p < .05). Physiological change attitude partially mediated the relationship between social contact motivation and the security dimension of active aging (r =0.15, p < .05). Positive aging attitude fully mediated the relationship between social contact motivation and the health dimension of active aging (r = 0.18, p < .01) and partially mediated the relationship between social contact motivation and the security dimension of active aging (r = 0.20, p < .01). 4. Conclusions This study examined the effects of social contact motivation and attitudes toward aging on active aging. The results demonstrated that improved social contact motivation and attitudes toward aging enhances active aging in older adults. Specifically, the results of this study suggest that (1)attitude toward physiological changes mediates the relationship between social contact motivation and the health, participation, and security dimensions of active aging and (2) positive aging attitude mediates the relationship between social contact motivation and the health and security dimensions of active aging. Therefore, older adults’ social contact motivation for learning influences their attitudes toward aging, including their attitudes toward physiological change; this in turn, enhances the health, participation, and security dimensions of active aging. 5. Limitations and Recommendations for Future Studies This research has several limitations. This study only recruited older adults in Taipei City. Future studies should recruit individual from different regions and age groups and explore a wider set of other variables, such as personality traits and barriers to participation in learning. They may also adopt a control group in their analyses to enable causal inference.

In order to optimize the rapid evaluation method and efficiency of asphalt aging characteristics, the infrared spectral information evaluation method of asphalt with different aging degrees was optimized based on DTW (dynamic time warping) algorithm, and the spectral information similarity SIS (spectral information similarity) evaluation index of aging asphalt is proposed. The results show that the minimum regularized distance based on DTW algorithm can reflect the amount of information about the cumulative changes in the structure of all chemical compositions in aged asphalt, which in turn indicates the degree of thermo-oxidative aging of asphalt. The correlation coefficient between SIS and the main characteristic peaks ( sulfinyl and carbonyl) is not less than 0. 954 4, which is strongly correlated with the aging degree of asphalt. The dispersion coefficient of the SIS index can be reduced by 92% compared with the single-component characterization index, which significantly reduces the probability of misclassification of the evaluation results of infrared spectral pattern. It shows that by combining with single-component qualitative evaluation, the SIS index can be used as the basis for evaluating the aging degree of asphalt, and the evaluation method can also be used as a reference for spectral information similarity identification and categorization research. [ABSTRACT FROM AUTHOR]

Stone artifacts can be seen as an important component of cultural heritage. A large portion of them is directly exposed to the natural environment, so their weathering process has long been a focus in academia. This paper summarizes the relevant experimental literature in the past ten years, analyzes and evaluates the experimental methods of artificial weathering of stone artifacts and the detection technology of their weathering effect. Artificial aging test of stone artificials refers to that researchers apply dry and wet cycling, salt crystallization, thermal stress and freeze-thaw weathering in laboratory to simulate outdoor environment, and use physical and chemical methods, such as infrared thermal wave imaging, rock medium ultrasound, nuclear magnetic resonance, and other technologies, to study the degradation mechanism, degree, and manifestation of stone artifacts. At the same time, by studying their texture structure, composition, porosity, thermal conductivity and other information, the weathering degree of the stone can be quantified. These works provide us with a theoretical foundation to understand the weathering mechanism of stone and help us protect stone artifacts in the future. It will help make the protection of cultural relics more scientific and effective, and provide strong support for the protection of precious cultural heritage. [ABSTRACT FROM AUTHOR]

The nonwoven geotextile has become the main variety of geotextiles due to its simple process, fast production speed, excellent mechanical properties, low cost and wide application. It has the functions of drainage, filtration, separation, reinforcement and protection, and is widely used in the fields of highway, railway, water conservancy and so on. Polypropylene is an inexpensive and excellent raw material with a wide range of sources, and boasts good acid and alkali resistance. Nonwoven geotextiles prepared from polypropylene can be better used in various types of projects, becoming the hot spot of research in the field of geotextiles in recent years. However, polypropylene tends to deteriorate over a long period of time due to external conditions such as light, temperature and oxygen, which reduces the service life of polypropylene nonwoven geotextiles and greatly restricts their popularisation and application in engineering. To improve the aging of polypropylene nonwoven geotextiles and to expand their application areas, it is necessary to conduct anti-aging treatment. To further improve the aging resistance of nonwoven geotextiles and prolong their service life, this study took ES fibers and PP fibers containing anti-aging masterbatch as raw materials, prepared PP/ES needle-punched nonwoven geotextiles by needle-punching process and PP/ES high-strength nonwoven geotextiles with UV aging resistance by impregnation of TiO₂ by post-finishing process, and investigated the effect of the aging-resistance process on the mechanical properties and UV aging resistance of PP/ES geotextiles. The study also investigated the effect of anti-aging process on the mechanical properties, hydrodynamic properties and anti-ultraviolet aging properties of PP/ES geotextiles, and analyzed the effect of adding anti-aging masterbatch and TiO₂ on the anti-aging properties of geotextiles by comparing them with pure PP geotextiles. It was found that the aging resistance of PP short-fiber nonwoven geotextiles and PP/ES nonwoven geotextiles was poor, and the fiber breakage and the decrease of thermal stability in the geotextile with the addition of anti-aging masterbatch were effectively alleviated, but the thermal bonding point was still greatly damaged; after the geotextiles were finished by TiO2 impregnation and rolling, a large number of TiO₂ particles appeared on the surface of the fiber, and the situation of fiber breakage, decrease of thermal stability and damage of the thermal bonding point was greatly improved; the geotextile with the addition of anti-aging masterbatch and TiO₂ finishing suffered the least damage and had the best thermal stability and UV resistance, and its longitudinal and transverse tensile strength was the best. The situation of fiber breakage, reduced thermal stability and destruction of thermal bonding point were greatly improved; while the geotextile with anti- aging masterbatch and TiO₂ finishing suffered the least damage, had the best thermal stability and UV resistance, and its longitudinal and transverse tensile strength retention rates decreased by only 26.55% and 26.76%, respectively, and its longitudinal and transverse elongation retention rates decreased by only 27.87% and 26.19%, respectively. [ABSTRACT FROM AUTHOR]

To investigate the effect of aging on the self-healing ability of styrene-butadiene-styrene block copolymer(SBS)-modified asphalt, a molecular model of SBS-modified asphalt was established. The reasonableness of the model was verified by calculating the glass transition temperature, cohesive energy density, and solubility parameter. Based on this, a self-healing model for SBS-modified asphalt was developed to evaluate its self-healing performance under different aging conditions. The results show that both asphalt aging and SBS aging will reduce the self-healing ability of SBS modified asphalt at room temperature. Notably, asphalt aging has a more significant impact on the self-healing ability of SBS-modified asphalt, while the effect of SBS aging is relatively minor. Compared to the self-healing model of “matrix asphalt + SBS”, the crack repair time in the “aging asphalt + aging SBS” self-healing model is significantly extended. Rejuvenation of asphalt is crucial for improving the crack repair performance of aged asphalt mixtures. The research results provide theoretical reference for the development and design optimization of road asphalt materials. [ABSTRACT FROM AUTHOR]

[Objective] The operating environment of rail transit trains is relatively complex, and composite materials on the trains are subject to deterioration during operation due to the aging phenomenon caused by harsh external factors. Therefore, it is necessary to study the effect of hygrothermal aging on the strength of carbon fiber composite equipment cabins. [Method] Hygrothermal aging tests and static mechanics (tensile, compression, shear) tests on carbon fiber composite are conducted to obtain their mechanical performance parameters before and after hygrothermal aging. An equipment cabin finite element model for a certain type of carbon fiber composite is established. The material parameters before and after hygrothermal aging are obtained by experimental methods, and the static strength of the equipment cabin under aerodynamic loads is calculated. [Result & Conclusion] The mechanical properties of woven carbon fiber composites after hygrothermal aging show different degrees of attenuation, with the compressive strength decreasing the most by 39.3%; compared with the initial state, the Tsai-Wu failure factors of each carbon fiber component show different degrees of increase. The degradation of carbon fiber strength and carbon fiber modulus due to the hygrothermal aging may cause the degradation of equipment cabin stiffness and bearing limit. [ABSTRACT FROM AUTHOR]

Skin photoaging, a phenomenon of premature skin aging due to prolonged exposure to ultraviolet (UV) radiation, manifests as wrinkles, loss of skin elasticity, pigmentation disorders, and age spots. Non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), play a crucial role in regulating gene expression and the development of skin photoaging. This review summarizes the molecular mechanisms of specific ncRNAs (such as miR-34a,miR-134,miR-1246,lncRNA H19-miR-296-5p-IGF2, lncRNA PVT1-miR-551b-3p-AQP3,lncRNAMeg3-miR-93-5p-epiregulin,circ-COL3A1-859267 and circ-0011129) in skin photoaging. Additionally, the review discusses the potential application of ncRNA-based therapies in photoaging, as well as the current challenges and future research directions. [ABSTRACT FROM AUTHOR]

The artificial accelerated aging resistance of paint films is an important indicator for evaluating the performance of coating systems throughout their entire life cycle・ The better the artificial accelerated aging resistance of the paint film, the better the UV anti-aging performance of the coating system, and relatively speaking, the longer its service life. This article optimizes the preparation, coating process, and spraying requirements of water-based paint for rail vehicles, and prepares the most excellent water-based paint composite coating・ It is then compared and tested with oil-based paint for 1 500 h of artificial accelerated aging(B lamp) resistance; use Fourier transform infrared spectroscopy(FTIR) and scanning electron microscopy (SEM) to characterize the changes in molecular structure and microstructure during this process・ The data results can infer that water-based paint on rail vehicles can completely replace oil-based paint. [ABSTRACT FROM AUTHOR]

To assess the effect of photostabilizers on the anti-light aging performance of warm mix asphalt for high alHtude and strong ultraviolet regions, three kinds of photostabilizers(Tinuvin770, UV-326, TiO2) were selected to prepare warm mix and anti-light aging modified asphalt binders, and they were subjected to three fundament indexes test, Brookfield viscosity test, low-temperature bending creep test, and timesweep fatigue test. The results show that three kinds of photostabilizers exhib让ed a excellent improvement on the anti-light aging performance of warm mix asphalt, TiO2 has the best improvement performance・ After ultraviolet aging, the viscosity aging index VAI and critical cracking temperature Tc of warm mix asphalt were inversely proportional to the dosage of photostabilizer, and the fatigue life of modified asphalt reached up to 2 300 times・ The recommended dosages of photostabilizers T770, UV326 and nano TiO2 are 0. 7%, 0・ 7% and 3%, respectively. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Dalian University of Technology / Dalian Ligong Daxue Xuebao is the property of Journal of Dalian University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

随着网络地理信息服务（network geographic information service，NGIS）向云服务演进，客户端瓦片缓存架构的应用局限性逐渐体现。为提升瓦片服务的性能，在老化算法的基础上，综合分析了瓦片访问长短期流行度和瓦片大小特征，设计了基于时空老化模型的服务端瓦片缓存置换算法（server-side cache replacement algorithm based on spatiotemporal aging model for tiles，SSAT），并利用谷歌全球底图瓦片和瓦片访问日志进行了仿真实验。结果表明，在不同缓存空间下，SSAT的缓存命中率均高于传统算法，缓存空间每增加1 MB，最多可以提高0.24%的请求命中率和0.23%的字节命中率；当缓存空间为500 MB时，SSAT能达到73%的请求命中率和76%的字节命中率，平均访问时长可缩短35%以上。SSAT能兼顾性能与资源消耗，具备高效性和扩展性。

Objective Self-perceptions of aging (SPA) are a critical issue in the mental health of middle -aged and older adults, yet the complex relationship with obesity remains insufficiently explored. This study analyzes the impact of obesity on SPA among this demographic. Methods Utilizing longitudinal follow-up data from the Health and Retirement Study (HRS) in the United States, logistic regression was employed to examine the relationship between Body Mass Index (BMI) and SPA, while restricted cubic splines (RCS) were used to reveal potential nonlinear associations. Results After adjusting for baseline age, gender, race, education level, marital status, number of chronic diseases, depressive symptoms, functional limitations, and baseline SPA levels, grade 2/3 obesity was associated with negative SPA (Oi=1.50!) 95%CI: 1.08-2.07), and a significant nonlinear relationship between BMI and SPA was observed (P-overall < 0.001, P-nonlinear = 0.042). Subgroup analysis indicated that among individuals under 80 years old, females, those with a high school education or lower, Caucasians, individuals with depressive symptoms, and those without functional limitations, grade 2/3 obesity was positively correlated with negative SPA. Conclusion Obesity in middle-aged and older adults is related to negative SPA. Healthcare professionals should pay attention to the potential psychological impacts of obesity during the aging process and develop more targeted prevention and intervention strategies to assist obese individuals in improving their mental health as they age. [ABSTRACT FROM AUTHOR]

Objective: B⁃cell specific moloney leukemia virus insertion site 1 (Bmi⁃1) has been extensively documented for its role in stem cell proliferation and differentiation, but its role in the brain of aged mice remains unclear. The study aimed to investigate the pathophysiological role of Bmi⁃1 in brain aging. Methods: Seventeen⁃month⁃old Bmi⁃1 heterozygous (Bmi⁃1 +/-) mice and wild⁃type (WT) mice were selected as experimental subjects. Behavioral testing, immunohistochemistry, and Masson staining techniques were used to compared the overall health status and long ⁃ term memory abilities of Bmi ⁃ 1 +/- mice with WT mice. HE staining, electron microscopy, and Western blot were employed to investigate the potential effects of Bmi⁃1 gene haploinsufficiency on the brain aging in mice. Results: Compared with the WT mice, Bmi ⁃ 1 +/- mice showed a diminished long ⁃ term spatial memory function (P < 0.05), accompanied by a reduction in neurogenesis in the hippocampal dentate gyrus (DG, P < 0.05), a decrease in neuronal numbers (P < 0.05), and a reduction in the grey matter volume (P < 0.05) . Further studies revealed that compared with the WT mice, Bmi⁃1+/- mice exhibited enlarged and swollen mitochondria in DG neurons, with an increased proportion of reduced mitochondrial cristae (P < 0.05), and a significant increase in the number of lipofuscin in the cytoplasm of DG neurons (P < 0.05) . Additionally, the expression levels of mitochondrial energy metabolism ⁃ related proteins, such as NADH dehydrogenase (ubiquinone) flavoprotein 2 (NDUFV2) and NADH dehydrogenase (ubiquinone) ferrithionein 3 (NDUFS3), were down⁃regulated in the DG region of Bmi⁃1+/- mice (P < 0.05), and the key catalytic enzyme dihydrolipoyl S⁃succinyltransferase (DLST) in the tricarboxylic acid cycle was also significantly down⁃regulated (P < 0.01) . Meanwhile, among the cell cycle factors regulated by Bmi ⁃1, the cyclin ⁃dependent kinase inhibitor p27 and oncoprotein p53 were significantly up⁃regulated (P < 0.05) . Conclusion：Half dose deletion of the Bmi⁃1 gene inhibits the generation of new neurons in the hippocampal region of aged mice, leading to a specific reduction in the volume of the hippocampal DG region and impairments in long ⁃term memory function. The underlying mechanism may be related to the abnormal expression of aging ⁃ related proteins p27 and p53, as well as neuronal mitochondrial degeneration. [ABSTRACT FROM AUTHOR]

Smoke aerosols contain many harmful substances and have become one of the major sources of indoor pollutants. The smoke aerosols released into the environment are easy to react with various oxidants presented in the room, namely the aging process of the smoke aerosol, which can produce secondary organic aerosols. The chemical composition of smoke aerosol is an important factor affecting its indoor aging process, but so far, the change behavior of the composition and particle size distribution of smoke aerosol during the aging process remains to be studied, and the aging analysis of novel tobacco products has not been reported. Therefore, the present study applied a house-made vacuum ultraviolet photoionization time-of-flight mass spectrometer to detect the chemical composition of the smoke aerosols produced by combustion cigarette, and new tobacco products, e.g., heat-not-burn tobacco products and e-cigarette, achieving the in-situ online characterization of their gas-phase and particulate-phase components. The results showed that the chemical composition of the smoke aerosols generated by the three types of tobacco products is significantly different, among which the component content and species abundance of the combustion cigarette are much greater than those of the novel tobacco products, and the overall signal intensity of combustion cigarette in the gas-phase and the particulate-phase is about 100 times and 10 times that of novel tobacco products, respectively. In addition, it was found that the particulate-phase mass spectra of novel tobacco products contain a large amount of glycerol, which is almost absent in combustion cigarette, and its intensity is even more than nicotine. The detected aerosol components contain many unsaturated compounds, which are easily oxidized in the environment and generate new ultrafine particles (UFPs). The Teflon chamber was used to simulate the aging process of the above three smoke aerosols with different O3 concentrations. The results of scanning mobility particle sizer showed that UFPs are generated in all of them. Corresponding to the results of photoionization mass spectrometry, the aging processes of the three smoke aerosols are completely different, in which the formation conditions of UFPs are related to the content and composition distribution of precursors. Specifically, the indoor concentration of O3 (observed in this experiment was 40 μg/m³ ) can promote the formation of UFPs with a geometric mean diameter of about 26 nm in the combustion cigarette, while the UFPs formation of novel tobacco products requires a higher concentration of O3 or a longer aging time. This is mainly facts that the whole composition concentration of the novel tobacco products is much lower than that of combustion cigarette, and the particulate-phase components contain a lot of glycerol. Due to the strong viscosity and encapsulation, glycerol may exist in the particulate-phase of the smoke aerosol in the form of coating other substances, such as nicotine, and further prevents the aging process of other substances, resulting in differences in particle size distribution. This study explains the reason of difference in UFPs formation of various smoke aerosols during the aging process and provides a basis for tobacco exposure risk assessment, which is expected to reveal the aging mechanism of smoke aerosols in the future. [ABSTRACT FROM AUTHOR]

In order to solve the problems in predicting the asphalt aging behavior, such as the large performance deviation between simulated aging asphalt and actual aging asphalt, the lack of scientific evaluation index easy to promote in the practical engineering, properties of natural aging SBS (Styrene Butadiene Styrene Triblock Copolymer) modified asphalt from an in-service expressway were tested by Asphalt Binder Quality Test System (ABQT) . Then, some indexes, including maximum creep deformation, elastic recovery rate, loading deformation rate coefficient and rebound deformation rate coefficient, were proposed to evaluate the changes of asphalt’s properties; meanwhile, the accuracy of evaluating asphalt aging behavior with the above indicators were also analyzed by analyzing the differences between the above indicators and conventional performance indicators in evaluating the asphalt aging properties. On this basis, the nonlinear prediction model for asphalt aging was established based on the above indicators, and the aging rate values of asphalt were obtained to analyze the degradation laws of asphalt properties under natural aging conditions, and ultimately a reasonable preventive maintenance time was proposed. Results showed that, the maximum creep deformation, loading deformation rate coefficient and rebound deformation rate coefficient can effectively characterize the decay process of asphalt aging properties under natural aging conditions. Meanwhile, the nonlinear prediction model for asphalt aging established based on the above indicators had strong applicability, which can achieve bidirectional calculation for asphalt performance and aging time. Furthermore, as the aging time prolonged, the aging rate values corresponding to the maximum creep deformation, loading deformation rate coefficient and rebound deformation rate coefficient all decayed in the form of a cubic function model； and the turning points of aging rate were 6. 67 a, 5. 56 a, and 6. 67 a, respectively. Therefore, considering the safety of asphalt mixture performance, it was suggested that 5. 56 a as the threshold for intervention in preventive maintenance measures to restore asphalt performance. [ABSTRACT FROM AUTHOR]

Direct-injection SBS modified asphalt has advantages such as easy quality control, low cost, and minimal pollution. It can address the issue of unstable quality in conventional wet-process SBS modified asphalt and has been gradually widely applied in recent years. This study investigated the aging resistance performance of direct-injection SBS modified asphalt at different dosages through short-term aging. By conducting temperature scanning tests, mid-temperature fatigue performance tests, low-temperature rheological property tests, and atomic force microscope tests on the aged direct-injection modified asphalt, the aging resistance performance of the SBS modified asphalt was studied from macroscopic to microscopic scales. The macroscopic experimental results indicated that the direct-injection SBS modified asphalt exhibited an increase in elastic components and fatigue life after short-term aging. During the aging process, the Guolu direct-injection SBS modified asphalt showed a secondary development phenomenon. The microscopic test results revealed that, after short-term aging, both conventional wet-process SBS modified asphalt and Liaohe direct-injection SBS modified asphalt exhibited reduced roughness due to changes in the content of the four components and the degradation of SBS. In contrast, the Guolu direct-injection SBS modified asphalt exhibited increased surface roughness due to further swelling development, consistent with the conclusions drawn from the macroscopic tests. [ABSTRACT FROM AUTHOR]

Objective This study aimed to explore the mediating effect of digital health literacy on the aging expectations and healthy aging of rural empty nest elderly. Methods Using a multi-stage sampling method, a questionnaire survey was conducted on 457 rural empty nest elderly individuals in Chengde, Hebei Province, with the use of general information questionnaires, digital health literacy assessment scales, healthy aging scales, and aging expectation scales. Mediation effect testing procedures and Bootstrap procedures were applied to analyze and validate the mediating effect. Results The scores for healthy aging, aging expectations, and digital health literacy among rural empty nest elderly in Chengde were (96.77±11.90), (34.98±8.96), and (34»90±17.18), respectively. Correlation analysis showed that digital health literacy, aging expectations, and healthy aging were positively correlated with each other among rural empty nest elderly in Chengde (P<0.001). The results of the mediation effect test indicated that digital health literacy partially mediated the relationship between aging expectations and healthy aging among rural empty nest elderly, with a mediation effect ratio of 14.53%. Conclusion The healthy aging of rural empty nest elderly in Chengde was at a moderate level. Aging expectations directly influenced healthy aging and also indirectly influenced healthy aging tlirough digital health literacy. [ABSTRACT FROM AUTHOR]

Brain aging is closely related to cognitive decline, neurodegenerative diseases, and vascular dementia. Hydrogen sulfide (H2S) can delay brain aging by regulating protein homeostasis, anti-oxidative stress, inhibiting inflammation, reducing brain cell apoptosis and improving microcirculation. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Northeastern University (Natural Science) is the property of Dongbei Daxue Xuebao and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the effect of Polydopamine (PDA) compound coating on the bonding strength of zirconia and self - bonding resin cement 3M ESPE Rely X™ U200 and the change of bonding strength after aging test. Methods Zirconia specimens were treated with three different surface treatments: "sandblasting," "sandblasting + silanization," and "sandblasting + PDA composite coating." These treated zirconia specimens were then bonded to resin blocks using 3M U200. The samples were divided into three groups for immediate shear bond strength testing, thermocycling aging, and pH cycling aging followed by shear bond strength testing. Statistical analysis was performed on the bonding strength data of each group. Results The "sandblasting + silanization" group showed the highest bonding strength between zirconia and resin, with statistically significant differences (P < 0.05) The "sandblasting + PDA composite coating" group had slightly higher bonding strength than the "sandblasting" group, but the difference was not statistically significant (P > 0.05) After aging tests, all surface treatment groups experienced a significant reduction in bonding strength (P < 0.05) The "sandblasting + PDA composite coating" group exhibited the greatest decrease in bonding strength, which was statistically significant (P < 0.05) The decrease in bonding strength for the " sandblasting + silanization" group was slightly higher than that of the "sandblasting" group, but the difference was not statistically significant (P > 0.05) Conclusion The PDA composite coating did not effectively enhance the bonding strength between zirconia and resin cement. Its bonding strength and stability after aging were inferior to those of the silanization coating. [ABSTRACT FROM AUTHOR]

Rust stain pollutants are one of the major diseases affecting textile relics, especially in artifacts of armors from the Ming and Qing Dynasties. The composite structure of silk/iron plates exacerbates this type of damage, impacting the lifespan and aesthetic value of relics. Currently, while enough analysis regarding the aging effects of environmental factors on silk fabrics has been secured, there is limited research on the aging patterns of silk fabrics contaminated with rust stains. Investigating the aging patterns of silk fabrics contaminated with rust stains can help delay the aging process of relics, which is crucial for the long-term preservation and scientific protection of armor-like relics. The aging of silk fabrics is the result of multiple factors, including light, moisture, heat, microorganisms, pollutants, etc. In current research on the aging of silk fabrics, artificially accelerated aging methods are primarily employed, which manifest changes in morphology, mechanical properties, chemical structure, crystallinity, etc. The aging of silk fabrics is complex, and single characterization methods have limitations. Thus, it is necessary to employ multiple methods, including morphology, tensile properties, infrared spectroscopy, thermogravimetric analysis, etc., to accurately characterize the degree of aging of silk fabrics. To understand the impact of rust stain contamination on the aging process of silk fabrics, comparative analyses were conducted under conditions of humidity, burial in soil, and UV light aging in the manuscript. The microscopic morphology, tensile properties, thermogravimetric analysis, and infrared spectroscopy were employed to compare the differences in aging between silk fabrics contaminated with rust stains and uncontaminated silk fabrics. The study analyzed the harm caused by rust contamination and its synergistic effects with environmental aging factors on silk fabrics. Starting from the degradation status of a Qing Dynasty armor caused by rust stains, this study focused on the influence of rust stains on the aging process of silk fabrics, providing theoretical support and guidance for the cleaning of rust stains. Experimental results showed that under the same conditions of humidity, burial, and UV light aging, the degree of aging of silk fabrics contaminated with rust spots was much more severe than that of uncontaminated samples, indicating a significant synergistic effect between rust stains and environmental conditions. Scanning electron microscopy, tensile, thermogravimetric, and infrared results all demonstrated that even without environmental aging, the degree of aging of silk fabrics contaminated with rust stains was more severe than that of uncontaminated samples. Rust stains caused roughness on the surface of silk fabrics and the appearance of original fibrous filaments. Rust stains restricted the slippage between yarns and fibers, leading to a decrease in elongation at break by 16.8% and a significant deterioration in overall tensile mechanical properties. Meanwhile, infrared results showed that the presence of rust stain contaminants accelerated the chemical structure transformation of silk protein, reducing the number of free amino groups and gradually flattening the characteristic peak of amide I band. This resulted in a decrease in the thermal stability of silk fibers, with significant increases of 6.6°C and 1.1% per minute, respectively, in the temperature at the maximum rate of weight loss and the differential weight loss rate. The study on the impact of rust stains on the aging of silk fabrics clearly identifies the harmfulness of rust stains to the long-term preservation of silk fabric cultural relics, providing a theoretical basis for the long-term preservation and scientific protection of armor-like relics. The research findings will contribute to a deeper understanding of the aging degradation patterns of silk fabrics and provide reference for the study of aging patterns of silk fabrics contaminated with other types of pollutants. [ABSTRACT FROM AUTHOR]

To determine the influence of ultraviolet (UV) aging on the microstructure of asphalt. The four-component, infrared spectrum, and nuclear magnetic resonance tests on four kinds of asphalt respectively were conducted, and the changes of the four components, characteristic peak, functional group and molecular structure indexes of asphalt under ultraviolet aging were investigated as well, such as hydrogen spectrum, carbon spectrum, hydrogen content, molecular structure parameters and other molecular structure indexes. The influence of molecular structure change on the chemical composition of asphalt was analyzed through the characterization of the molecular structure index to the chemical composition index. The results show that asphaltene molecules tend to form after ultraviolet aging, and the asphaltene conversion source is mainly aromatic fraction. The fact is founded that the higher the content of asphaltene, the higher the loss rate after aging is. Meanwhile, the carbonyl group and sulfoxide group increase rapidly first and then flatten out with the aging time. The carbonyl group index can represent the aging of asphalt, while the sulfoxide group index can evaluate the antiaging ability of asphalt. Under ultraviolet aging, the degree of condensation, the increase of cycloalkyl substituents, the substitution of hydrogen, and the structure dissimilation of the asphalt aromatic ring occur. At the same time, a high UV photon energy can also cause fatty carbon to break bonds, which can improve the chemical stability of the fatty carbon connected to the aromatic ring. It can be seen from the characterization analysis that the chemical composition of asphalt is mainly affected by the aromatic structure, branching degree, and condensation index of the aromatic ring system. [ABSTRACT FROM AUTHOR]

As emerging contaminants, microplastics (MPs) and antibiotics are often detected simultaneously in the water environment, and antibiotics in the water environment are often found on the surface of MPs. MPs can absorb, collect and carry various organic pollutants in water environment through surface adsorption and migration. Compared with the original MPs, the aging MPs has stronger adsorption capacity due to smaller particle size, larger specific surface area, and more adsorption sites. The environmental aging mode of MPs and the adsorption behavior of MPs on various antibiotics in water environment after aging were mainly reviewed, The aging method of MPs and the influencing factors and adsorption mechanism of antibiotics was summarized, and prospects for the aging problem of MPs and the effect on antibiotic adsorption was put forward. [ABSTRACT FROM AUTHOR]

AIM: To investigate the effects of aerobic and anti-resistance exercise on skin aging in SAMP8 mice via interleukin-18 （IL-18）/IL-18 receptor （IL-18R） pathway and provide new concepts for anti-skin aging and prevention and treatment of chronic inflammatory skin-related diseases. METHODS: Twenty-four healthy male 28-week-old rapidly aging SAMP8 mice were randomly divided into model group, aerobic exercise group, and resistance exercise group, with 8 mice in each group. Eight same-aged rapidly aging SAMR1 mice were used as control group. The mice in aerobic exercise group underwent running table training at a constant speed （1 time per day, 5 times per week） for 8 weeks, and those in model group underwent incremental weight-bearing ladder training for 8 weeks （1 time every other day, 3 times per week）. The HE staining was performed to observe the structural changes of the epidermis and dermis, and Weigert staining was conducted to observe the changes in skin elastic fibers. Immunohistochemistry was performed to observe the expression of skin aging markers P16 and P21. The ELISA was used to detect the concentrations of serum and skin inflammatory factors IL-18, IL-1β and tumor necrosis factor-α （TNF-α） and the levels of dermal IL-18R and IL-18 binding protein （IL-18BP）. Double immunofluorescence staining of IL-18 and IL-18R was conducted. The RT-qPCR was used to detect the mRNA expression levels of IL-18 and IL-18R. RESULTS: Compared with control group, the mice in model group exhibited obvious signs of aging. The results of HE staining revealed indications such as rough skin texture and skin thinning. Weigert staining revealed the following: the elastic fibers were disordered, separated, thickened, shortened, twisted, and broken. The expression levels of P16 and P21 proteins in the epidermis and dermis were elevated （P<0. 01）. Serum and skin IL-1β, TNF-α and IL-18 levels were significantly higher. Skin IL-18R content was significantly higher, and IL-18BP content was significantly lower （P<0. 05 or P<0. 01）. Colocalization phenomenon existed between IL-18 and IL-18R. Skin IL-18 and IL-18R mRNA expression levels were significantly higher （P<0. 01）. Compared with model group, the skin appearance of the aerobic exercise and resistance exercise groups was significantly improved （P< 0. 05 or P<0. 01）. The thickness of the epidermis （P<0. 05） and dermis increased significantly in resistance exercise group（ P<0. 01）, and the elastic fibers were arranged in a more neat and orderly manner. The expression of P16 protein in the skin was decreased in aerobic exercise group （P<0. 05）. The levels of serum TNF-α, and serum and skin IL-18 were decreased in aerobic exercise group（ P<0. 05）. The levels of serum and skin IL-1β, TNF-α and IL-18 in the resistance exercise group were decreased（ P<0. 05 or P<0. 01）. Skin IL-18R content was significantly decreased in both aerobic and resistance exercise groups （P<0. 01）. IL-18BP content was significantly increased （P<0. 01）, and colocalized expression levels of IL-18 and IL-18R were significantly decreased. The mRNA expression of IL-18 and IL-18R was significantly decreased in both aerobic and resistance exercise groups （P<0. 01）. CONCLUSION: Both aerobic and resistance exercise delay age-increased skin aging in rapidly aging mice, and the IL-18/IL-18R signaling pathway down-regulated by exercise may be the pathway of this effect. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Dalian University of Technology / Dalian Ligong Daxue Xuebao is the property of Journal of Dalian University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

本研究聚焦於「屆退人員貢獻老化退休準備核心知能指標之建構」，為我國即將退休的中高齡者建構一套系統化的貢獻老化退休準備核心知能指標，藉此探索出對退休準備教育的啟示。研究者採用半結構訪談與德懷術問卷調查法，蒐集退休人員繼續貢獻社會的意願、途徑 及應具備的退休準備核心知能等資料，進行質性與量化的分析，以建構出「屆退人員貢獻老化退休準備核心知能指標」。研究結果歸納出屆退人員貢獻老化退休準備核心知能指標，包括四個向度：貢獻意願、貢獻障礙、貢獻準備及貢獻途徑；八個構面：內在原因、外在原因、個人障礙、環境障礙、內在準備、外在準備、貢獻類型及貢獻方式，共 72 項指標，並得到對 未來規劃實施退休準備教育的重要啟示。 This research focused on constructing the core competence indicators of contributive aging retirement preparation among people approaching retirement, and the implications of future preretirement education are described in this paper. This study adopted the Delphi technique to collect and analyse data, constructing the core competence indicators of contributive aging retirement preparation among people close to retirement. This study concluded that 72 indicators exist for contributive aging retirement preparation, and that these indicators encompass four areas: (a) intentions of contribution, (b) disabilities of contribution, (c) preparations of contribution, and (d) paths of contribution. (a) is categorized into two surfaces: intrinsic factors and external factors. (b) is categorized into two surfaces: personal disabilities and environmental disabilities. (c) is categorized into two surfaces: intrinsic preparation and external preparation. (d) is categorized into two surfaces: contributing styles and contributing types. The innovation of this study is constructing the core competence indicators of contributive aging among people close to retirement, a subject that has seldom been researched in Taiwan and overseas. The value of this study lies in the indicators that have been developed to assess retirement preparation among people approaching retirement.

在电力系统中,当受到强大的冲击电流时,电力光缆将在高于导体最高工作温度10%的温度场环境下工作,长时间的高温老化工况状态对光纤复合低压电缆（OPLC）光单元中的光纤造成极大的负效应,严重地影响了整个电网的安全运行。针对上述问题,为了研究单模光纤受热前后机械性能变化情况,分析高温老化对光纤的损伤程度,文章通过模拟高于以聚氯乙烯绝缘的OPLC导体温度10%的温度场环境,测试了不同温度和老化时间段下单模光纤的断裂强度、断裂伸长率和光纤涂层剥离力等光纤机械性能,基于测试数据,运用线性拟合的统计方法,研究了在该温度场环境下老化前后光纤机械特性的变化趋势。试验结果表明,OPLC中光纤的应力腐蚀敏感性参数比涂覆剥离力特性受热更敏感,随着老化时间增长,不同老化时长后涂覆剥离力比应力腐蚀敏感性参数的差值变化量更大,耐热性能更差。基于机械性能的测试结果,文章提出了增加光单元耐热层的优化意见。

近年來高齡人口數逐年增多，但現代老人的地位卻因工商業社會的發展而逐年下降，致使年齡歧視現象充斥於社會之中。如何能夠消弭年齡歧視的蔓延，有賴於中小學教師具有老化教育的相關培訓。因此，本研究旨於規劃 18 小時的「教師老化教育培訓方案」是否能有效地改善中小學教師的老化知識、態度與教學行為意向？本研究採取「不等組前後測設計」，有效樣本實驗組 33 人、控制組 51 人。主要研究發現有：一、實驗組教師在接受「老化教育培訓方案」後，其老化知識、態度與教學行為意向上的得分，顯著較其培訓前佳；二、控制組教師在未接受「老化教育培訓方案」的情況下，其老化知識、態度與教學行為意向上的前後測得分，無顯著差異；三、實驗組教師在接受「老化教育培訓方案」後，其老化知識、態度與教學行為意向上的得分，顯著較控制組教師佳。 The aging population is gradually increasing because people are living longer. Older people are often portrayed as insignificant, unhealthy, sad, and dependent in contemporary cultures and values. Therefore, it is pertinent to improve the knowledge, attitudes, and behavioral intentions toward aging and older people held by elementary and secondary teachers. The researcher designed an 18-hour Aging Education Training (AET) program to test whether it influenced the knowledge, attitudes, and behavioral intentions of the participants. Overall, 33 teachers were in an experimental group and 51 teachers were in a control group. The results revealed that the teachers who joined the AET program had improved knowledge, attitudes, and behavioral intentions toward aging people after the training program. Conversely, there was no significant difference in the knowledge, attitudes, and teaching behavior toward aging people in the teachers who did not join the AET program. Overall, the teachers who joined the AET program had significantly greater knowledge, attitudes, and teaching behavior toward aging people compared with the teachers who did not join the AET program.

Starting from the essence of asphalt aging, triethoxysilane was used to hydrogenate with aged asphalt, and the carbonyl and sulfoxide groups in the aged asphalt were changed into low polarity substances. Considering that the active end group of aged asphalt can induce the accelerated aging of new asphalt, the active end group of aged asphalt was capped by free radical inhibitor isocyanate. The mechanism of chemical repair of aged asphalt was investigated by testing the chemical structure and polarity changes before and after catalytic hydrogenation and end group sealing. Using matrix asphalt as a reference, the chemical repair effect of catalytic hydrogenation and end-group sealing on aged asphalt was evaluated by analyzing and testing the changes of macroscopic properties of aged asphalt before and after catalytic hydrogenation and end-group sealing. Finally, the internal relationship between chemical structure and low temperature performance of aged asphalt was established through the linkage analysis of infrared spectrum and low temperature bending test results. The results showed that the chemical structure of aged asphalt was changed in essence by catalytic hydrogenation and end-group sealing. The carbonyl groups and sulfoxide groups in aged asphalt were converted into ester by triethoxysilane, and the hydroxyl groups in aged asphalt were converted into ester by isocyanate, which reduced the activity and the polarity of the aged asphalt. After catalytic hydrogenation and end-group sealing, the dielectric constant and viscosity of aged asphalt decreased by 27.3 % to 3.2, while the adhesion to limestone increased by 1 5.8%, and the change range of low temperature stiffness modulus and creep rate pair reached more than 14. 0%• The polarity of aged asphalt was significantly weakened, and the intermolecular force and viscosity were significantly reduced, so the adhesiveness and low temperature performance were significantly improved. There is a good correspondence between stiffness modulus and creep rate and functional group index of aged asphalt. [ABSTRACT FROM AUTHOR]

Tn order to improve the performance of recycled asphalt pavement (RAP), different dosages of activated crumb rubber (ACR) and waste cooking oil (WCO) were added to aged asphalt, which was analyzed in terms of rheological properties and microscopic characteristics. The results show that WCO can not only be used as a rejuvenator to improve aged asphalt, but also as a solubilizer to fully dissolve the crumb rubber to enhance the overall performance of asphalt. Fluorescence microscopy (FM) analysis showed that moderate amount of WCO helps to improve the compatibility of crumb rubber in asphalt. The Fourier transform infrared spectroscopy (FTTR) results indicate that the aged asphalt rejuvenation process is a physical co-mingling, while the crumb rubber modification process is accompanied by a small amount of chemical reaction. Finally, combining the rheological results and microstructure of modified recycled asphalt, the optimal dosages of WCO and ACR were recommended to be 10% and 18%, respectively. [ABSTRACT FROM AUTHOR]

In order to analysis the effect of temperature on thermal oxidative aging behavior of latex sponge. The morphology and structural changes of latex sponge after aging directly affect its product use value, and its aging behavior is closely related to temperature. This study is not limited to mechanical properties. By measuring the changes of whiteness index, yellowness index, crosslink density, and indentation hardness of latex sponge at 70 ℃ and 120 ℃, the thermal oxidative aging behavior of materials under different temperature conditions was analyzed. The experimental results show that the peak of the yellowness index is reached at 86 hours at 120 ℃, the pore structure disappears and residue powder is formed on the surface. The crosslinking density is initially increased first and subsequently decreased, and the indentation hardness is sharply increased in a short time. Under the condition of 70 ℃, a slow decrease in the whiteness index of the material is noted. The other indexes display a slow upward trend, and the complete pore structure is retained. It is concluded that the change procedure and final shape of the latex sponge morphology and structure during the aging process under the condition of 120 ℃ are significantly different from those under the relatively low temperature condition. The product value is rapidly lost due to thermal oxidative aging behavior, and the thermal oxygen aging resistance of 80NR latex sponge needs improvement. [ABSTRACT FROM AUTHOR]

Objective To explore the mediating effect of self-perceived aging on the relationship between digital health literacy and technophobia of the rural elderly. Methods By using the method of multi-stage sampling, 503 rural elderly in Hebei Province were investigated by general data questionnaire, techno phobia scale, simplified self-perceived aging scale, and digital health literacy assessment scale from July to August, 2023. The mediating effect test program was used for mediating analysis and Bootstrap test was used for verification. Results The scores of technophobia, self-perceived aging, and technophobia of the elderly in rural areas of Hebei Province were 36.40± 10.22, 51.99±8.24, and 39.76±13.82, respectively. Pearson correlation analysis showed that digital health literacy was negatively correlated with technophobia and self-perceived aging (r= 0.433, P < 0,001; r=0.454, P < 0.001), while self-perceived aging was positively correlated with technophobia (r=0.401, P < 0,001), The mediating effect test results showed that self-perceived aging had mediating effect between digital health literacy and technophobia of the rural elderly, and the mediating effect accounted for 40.0%. Conclusion Digital health literacy and self-perceived aging of the elderly directly affect technophobia. At the same time, digital health literacy can also indirectly affect technophobia through self-perceived aging. [ABSTRACT FROM AUTHOR]

Objective To explore whether aging is an independent factor in speech perception ability and to clarify the impact mode of aging on the ability to perceive speech cues. Methods This study recruited normal-hearing youth group (n=10, average age of 24 years) and elderly group (n=15, average age of 67 years). Closed-set mandarin speech (CMS) was used to evaluate the speech recognition thresholds (SRTs) of the two group sunder four different speech perception cues (“baseline” condition, “fundamental frequency” condition, “spatial” condition, and “fundamental frequency + spatial” condition). The effect of aging on the ability to utilize fundamental frequency cues and/or spatial cues was quantitatively assessed by comparing SRTs under the four conditions. Results RM-ANOVA showed that under the conditions of “baseline”, “fundamental frequency” and “spatial”, the SRTs of the elderly group were higher (worse) than those of the young group (All P<0.05). The difference between the two groups under the condition of “fundamental frequency + space” showed no statistical significance (P>0.05). When analysis was performed with hearing threshold as a covariate, there was no significant difference in SRT between the elderly group and the young group in the “spatial” condition (P>0.05). Under the conditions of “fundamental frequency”, “spatial” and “fundamental frequency + space”, the MRs of the elderly group decreased compared with the young group, but the difference was not statistically significant (P>0.05). Conclusions The speech perception ability of the elderly in complex contexts is significantly worse than that of the young people. However, when speech has both fundamental frequency and spatial cues, the elderly can still use the two cues comprehensively to achieve similar perceptual performance as young people. Excluding the effect of hearing acuity, aging significantly weakens the ability to perceive speech fundamental frequency cues, but has no significant effect on the ability to utilize spatial cues. [ABSTRACT FROM AUTHOR]

Aim To explore the preventive effect and potential mechanism of β-blockers in vascular aging of spontaneously hypertensive rat (SHR). Methods 24 three-month-old male spontaneously hypertensive rats were randomly divided into placebo group, nifedipine group, nifedipine+metoprolol group and metoprolol group, treated with edible starch, 60 mg nifedipine sustained-release tablets, 40 mg nifedipine sustained-release tablets+75 mg metoprolol sustainedrelease tablets and 150 mg metoprolol sustained-release tablets, respectively. The rats fed with common diets for 9 months, and the blood pressure, heart rate and other general condition of the rats were dynamically measured. HE staining was used to observe the morphological characteristics of femoral aorta in rats. The vasomotor function of isolated femoral artery was tested by circumferential perfusion, immunofluorescence histological staining and real-time polymerase chain reaction (RT-PCR) were used to determine the expression of aging related genes p53 and p21, as well as endoplasmic reticulum stress related genes CHOP and XBP1. Results Compared with placebo group, systolic blood pressure decreased by about 30%, diastolic blood pressure decreased by about 20%, and heart rate decreased by 9%, 36% and 41% (all P<0. 01) in nifedipine group, nifedipine+metoprolol group and metoprolol group, respectively. Compared with placebo group, the systolic and diastolic functions of nifedipine group, nifedipine+metoprolol group and metoprolol group were significantly improved and the intima-media thickness decreased by 24%, 14% and 37% (all P<0. 01), respectively. Compared with nifedipine group and nifedipine+metoprolol group, the systolic and diastolic functions of metoprolol group were significantly improved and the intima-media thickness decreased by 18% and 27% (all P<0. 01), respectively. Compared with the placebo group, the expression levels of p53 protein, p53 mRNA, p21 protein, p21 mRNA, CHOP protein, CHOP mRNA, XBP1 protein and XBP1 mRNA in nifedipine group decreased by 35% (P<0. 01), 23% (P<0. 05), 25% (P<0. 01), 3% (P>0. 05), 51% (P<0. 01), 24% (P>0. 05), 21% (P<0. 01) and 23% (P>0. 05), the nifedipine+metoprolol group decreased by 36% (P<0. 01), 42% (P<0. 01), 4% (P>0. 05), 24% (P<0. 05), 32% (P<0. 01), 44% (P<0. 05), 13% (P<0. 01) and 42% (P<0. 05), the metoprolol group decreased by 47% (P<0. 01), 43% (P<0. 01), 42% (P<0. 01), 49% (P<0. 01), 78% (P<0. 01), 56% (P< 0. 01), 32% (P<0. 01) and 81% (P<0. 01). Compared with nifedipine group and nifedipine+metoprolol group, metoprolol group further inhibited the expression of genes related to aging and endoplasmic reticulum stress. Conclusions The arteries of spontaneously hypertensive rats show significant aging. β-blockers are better than calcium channel blockers in inhibiting vascular aging of spontaneously hypertensive rats, and at high doses β-blockers improve the degree of vascular aging better than combination therapy, and their mechanism may be related to the inhibition of endoplasmic reticulum stress. [ABSTRACT FROM AUTHOR]

Insulating oil is an important component of transformers. Its quality directly affects the performance of the insulation system and the operation safety of the transformer. As working years increase, insulating oil interacts with oxygen, water, and other impurities in the environment to form a variety of aging products. This results in a decrease in its insulation and heat dissipation performance, which in turn causes failures. Therefore, analyzing and detecting transformer insulating oil is an important means to understand the working status of transformers. The analysis results are the reference basis for transformer maintenance and replacement of new oil. The ultraviolet-visible absorption spectrum was used to analyze insulating oil of different working years. The correlation between the aging degree of insulating oil and its ultraviolet spectral characteristics was obtained. The ultraviolet spectrum of furfural, a symbolic aging product, was studied by quantum chemical calculation. The mechanism corresponding to the ultraviolet-visible spectral characteristics of furfural was analyzed. The research results confirm the effectiveness of UV-visible spectroscopy in analyzing the aging degree of transformer insulating oil. The relevant results can be used as a reference for transformer detection. [ABSTRACT FROM AUTHOR]

In the high altitude area, the performance of asphalt mixture deteriorates due to the influence of harsh environmental factors. Among them, the large irradiance of ultraviolet makes the pavement appear “white” in a short time, which affects the service life of asphalt surface. Several anti-ultraviolet aging composite modified asphalt schemes were selected to study the anti-ultraviolet aging of indoor asphalt mixture. The ultraviolet aging simulation test of asphalt mixture was carried out by means of the self-developed weather-resistant aging chamber, and the effect of the composite modified asphalt on the ultraviolet aging resistance of the mixture was studied. The results showed that compared with SBS modified asphalt, the fracture energy of L64 and L4 was 8. 16% and 5. 86% higher than that of SBS modified asphalt before aging, respectively. The composite modified asphalt after ultraviolet aging of L64 and L4 had better crack resistance, fatigue resistance and high temperature stability. The research results have great engineering value for preventing ultraviolet aging of asphalt pavement. [ABSTRACT FROM AUTHOR]