443 results on '"Ziebland S"'
Search Results
2. Communication practices for delivering health behaviour change conversations in primary care: a systematic review and thematic synthesis
- Author
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Albury, C., Hall, A., Syed, A., Ziebland, S., Stokoe, E., Roberts, N., Webb, H., and Aveyard, P.
- Published
- 2019
- Full Text
- View/download PDF
3. Outcome reporting across randomised controlled trials evaluating therapeutic interventions for pre‐eclampsia
- Author
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Duffy, JMN, Hirsch, M, Kawsar, A, Gale, C, Pealing, L, Plana, MN, Showell, M, Williamson, PR, Khan, KS, Ziebland, S, McManus, RJ, van ‘t Hooft, Janneke, Brown, Mark, Grobman, William, Karumanchi, S, Lucas, Nuala, Magee, Laura, Mol, Ben, Stark, Michael, Thangaratinam, Shakila, Wilson, Mathew, and von Dadelszen, Peter
- Published
- 2017
- Full Text
- View/download PDF
4. Core outcome sets in womenʼs and newborn health: a systematic review
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Duffy, JMN, Rolph, R, Gale, C, Hirsch, M, Khan, KS, Ziebland, S, McManus, RJ, van‘t Hooft, Janneke, Brown, Mark, Grobman, William, Fitzpatrick, Ray, Karumanchi, S, Lucas, Nuala, Magee, Laura, Mol, Ben, Stark, Michael, Thangaratinam, Shakila, Wilson, Mathew, von Dadelszen, Peter, and Williamson, Paula
- Published
- 2017
- Full Text
- View/download PDF
5. Standardising definitions for the pre-eclampsia core outcome set: A consensus development study
- Author
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Duffy, J. M. N., Cairns, A. E., Magee, L. A., von Dadelszen, P., van 't Hooft, J., Gale, C., Brown, M., Chappell, L. C., Grobman, W. A., Fitzpatrick, R., Karumanchi, S. A., Lucas, D. N., Mol, B., Stark, M., Thangaratinam, S., Wilson, M. J., Williamson, P. R., Ziebland, S., Mcmanus, R. J., Abalos, E. J., Adamson, C. C. D., Akadri, A. A., Akturk, Z., Allegaert, K., Angel-Muller, E., Antretter, J., Ashdown, H. F., Audibert, F., Auger, N., Aygun, C., Babic, I., Bagga, R., Baker, J. M., Beebeejaun, Y., Bhakta, P., Bhandari, V., Bhattacharya, S., Blanker, M. H., Bloomfield, F. H., Bof, A., Brennan, S. M., Broekhuijsen, K., Broughton Pipkin, F., Browne, J. L., Browning, R. M., Bull, J. W., Butt, A., Button, D., Campbell, J. P., Campbell, D. M., Carbillon, L., Carthy, S., Casely, E., Cave, J. A., Cecatti, J. G., Chamillard, M. E., Chassard, D., Checheir, N. C., Chulkov, V. S., Cluver, C. A., Crawford, C. F., Daly, M. C., Darmochwal-Kolarz, D. A., Davies, R. E., Davies, M. W., Dawson, J. S., Dobson, N., Dodd, C. N., Donald, F., Duley, L., Epstein-Mares, J., Erez, O., Evans, E., Farlie, R. N., Ferris, A. V., Frankland, E. M., Freeman, D. J., Gainder, S., Ganzevoort, W., Gbinigie, O. A., Gerval, M. -O., Ghosh, S. K., Gingel, L. J., Glogowska, M., Goodlife, A., Gough, K. L., Green, J. R., Gul, F., Haggerty, L., Hall, D. R., Hallman, M., Hamilton, L. M., Hammond, S. J., Harlow, S. D., Hays, K. E., Hickey, S. C., Higgins, M., Hinton, L., Hobson, S. R., Hogg, M. J., Hollands, H. J., Homer, C. S. E., Hoodbhoy, Z., Howell, P., Huppertz, B., Husain, S., Jacoby, S. D., Jacqz-Aigrain, E., Jenkins, G., Jewel, D., Johnson, M. J., Johnston, C. L., Jones, P. M., Kantrowitz-Gordon, I., Khan, R. -U., Kirby, L. J., Kirk, C., Knight, M., Korey, M. T., Lee, G. J., Lee, V. W., Levene, L. S., Londero, A. P., Lust, K. M., Mackenzie, V., Malha, L., Mattone, M., Mccartney, D. E., Mcfadden, A., Mckinstry, B. H., Middleton, P. F., Mills, D. J., Mistry, H. D., Mitchell, C. A., Mockler, J. C., Molsher, S. -A., Monast, E. S., Moodley, J., Mooij, R., Moore, E. L., Morgan, L., Moulson, A., Mughal, F., Mundle, S. R., Munoz, M. A., Murray, E., Nagata, C., Nair, A. S., Nakimuli, A., Nath, G., Newport, R. S., Oakeshott, P., Ochoa-Ferraro, M. R., Odendaal, H., Ohkuchi, A., Oliveira, L., Ortiz-Panozo, E., Oudijk, M. A., Oygucu, S. E., Paech, M. J., Painter, R. C., Parry, C. L., Payne, B. A., Pearson, E. L., Phupong, V., Pickett, N., Pickles, K. A., Plumb, L. K., Prefumo, F., Preston, R., Ray, J. G., Rayment, J., Regan, L. V., Rey, E., Robson, E. J., Rubin, A. N., Rubio-Romero, J. A., Rull, K., Sass, N., Sauve, N., Savory, N. A., Scott, J. R., Seaton, S. E., Seed, P. T., Shakespeare, J. M., Shand, A. W., Sharma, S., Shaw, T. Y., Smedley, K. L., Smith, D., Smith Conk, A., Soward, D., Stepan, H., Stroumpoulis, K., Surendran, A., Takeda, S., Tan, L., Theriot, B. S., Thomas, H. F., Thompson, K., Thompson, P. I., Thompson, M. J., Toms, L., Torney, K. L. H. T., Treadwell, J. S., Tucker, K. L., Turrentine, M. A., Van Hecke, O., Van Oostwaard, M. F., Vasquez, D. N., Vaughan, D. J. A., Vinturache, A., Walker, J., Wardle, S. P., Wasim, T., Waters, J. H., Whitehead, C. L., Wolfson, A., Yeo, S., Zermansky, A. G., (iHOPE), International Collaboration to Harmonise Outcomes for Pre-eclampsia, Life Course Epidemiology (LCE), University of Oxford, University College London, King’s College London, Academic Medical Center, Imperial College London, St George Hospital and University of New South Wales, Northwestern University, Cedars-Sinai Medical Center, London North West University Healthcare NHS Trust, Monash University, University of Adelaide, Barts and The London School of Medicine and Dentistry, University of Sheffield, University of Liverpool, Centro Rosarino de Estudios Perinatales, Chelsea and Westminster Hospital NHS Foundation Trust, Babcock University, Ailem Academic Counselling, KU Leuven, Universidad Nacional de Colombia, Northwell Health, Université de Montréal, University of Montreal Hospital Centre, Ondokuz Mayıs University, Prince Sultan Military Medical City, Postgraduate Institute of Medical Education and Research, Fetal Medicine Research Institute, University Hospital Limerick, Drexel University, University of Aberdeen, University of Groningen, University of Auckland, Haaglanden Medisch Centrum, Nottingham University Medical School, Utrecht University, King Edward Memorial Hospital for Women, Imperial College Healthcare NHS Trust, Jean-Verdier Hospital, Downland Practice, Universidade Estadual de Campinas (UNICAMP), Université Lyon, University of North Carolina School of Medicine, South Ural State Medical University, Stellenbosch University, Irish Neonatal Health Alliance, University of Rzeszow, Royal Brisbane and Women’s Hospital, Nottingham University Hospitals NHS Trust, University Hospitals of Leicester, North Bristol NHS Trust, University of Nottingham, Soroka University Medical Center Ben Gurion University of the Negev, St George’s University Hospitals NHS Foundation Trust, Hospitalsenhed Midt, University of Glasgow, Amsterdam Universitair Medische Centra, All India Institute of Medical Sciences Patna, Luton and Dunstable University Hospital, Khyber Medical University Institution of Medical Sciences, Midwife Mid Essex Hospitals NHS Trust, University of Oulu, University of Michigan, Bastyr University, Irish Nurses and Midwives Organisation, University of Toronto, Barts Health NHS Trust, University Hospitals Plymouth NHS Trust, Burnet Institute, Aga Khan University, Medical University of Graz, Homerton University Hospital NHS Foundation Trust, Mount Royal University, Université de Paris, Royal Surrey County Hospital, University Hospital Southampton NHS Foundation Trust, University of Washington School of Nursing, Evelina London Children's Hospital Neonatal Unit, University of Sydney, University of Leicester, Academic Hospital of Udine, NHS Borders, Weill Cornell Medical College, University of Dundee, University of Edinburgh, South Australian Health and Medical Research Institute, Monash University and Monash Health, United Lincolnshire Hospitals NHS Trust, University of Kwa Zulu-Natal, Beatrix Hospital, Keele University, Government Medical College, Institut Catala de la Salut. IdiapJgol, National Center for Child Health and Development, Basavatarakam Indo-American Cancer Hospital and Research Institute, Axon Anaesthesia Associates, Pennine Acute Hospitals NHS Trust, University of London, Norfolk and Norwich University Hospital, Jichi Medical University School of Medicine, Universidade Estadual Paulista (UNESP), National Institute of Public Health, University of Kyrenia, King Edward Memorial Hospital, Amsterdam University Centres, University of British Columbia, Chulalongkorn University, University of Brescia, University Of British Columbia, University of Montreal, Women's Clinic of Tartu University Hospital, Universidade Federal de São Paulo (UNIFESP), Université de Sherbrooke, University Hospital of Wales, University of Iowa, King's College London, Westmead Hospital, Princess Royal Maternity, Leipzig University, Centre Hospitalier Public du Cotentin, Lewisham and Greenwich NHS Trust, Juntendo University Faculty of Medicine, Western Sydney University, National Institute of Health Research, University of Washington, Baylor College of Medicine, Capelle aan den Ijssel, Sanatorio Anchorena, Oxford University Hospitals NHS Foundation Trust, University of Leeds, Institute of Medical Sciences, UPMC Magee Womens Hospital, Penn Medicine Princeton Health, University of North Carolina at Chapel Hill, and Obstetrics and Gynaecology
- Subjects
Adult ,medicine.medical_specialty ,Consensus ,Delphi Technique ,Standardization ,Birth weight ,Psychological intervention ,Randomised controlled trials ,030204 cardiovascular system & hematology ,Outcome (game theory) ,03 medical and health sciences ,Hypertension in pregnancy ,Outcome measure ,0302 clinical medicine ,Pre-Eclampsia ,Pregnancy ,Consensus development study ,Internal Medicine ,medicine ,Humans ,Set (psychology) ,030219 obstetrics & reproductive medicine ,Eclampsia ,business.industry ,Pregnancy Outcome ,Obstetrics and Gynecology ,Core outcome set ,Reference Standards ,medicine.disease ,Pre-eclampsia ,Pregnancy Complications ,Core (game theory) ,Treatment Outcome ,Systematic review ,Family medicine ,1114 Paediatrics and Reproductive Medicine ,Female ,International Collaboration to Harmonise Outcomes for Pre-eclampsia (iHOPE) ,business - Abstract
Made available in DSpace on 2022-04-28T19:29:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-07-01 Medical Research Council Canada National Institute for Health Research Objectives: To develop consensus definitions for the core outcome set for pre-eclampsia. Study design: Potential definitions for individual core outcomes were identified across four formal definition development initiatives, nine national and international guidelines, 12 Cochrane systematic reviews, and 79 randomised trials. Eighty-six definitions were entered into the consensus development meeting. Ten healthcare professionals and three researchers, including six participants who had experience of conducting research in low- and middle-income countries, participated in the consensus development process. The final core outcome set was approved by an international steering group. Results: Consensus definitions were developed for all core outcomes. When considering stroke, pulmonary oedema, acute kidney injury, raised liver enzymes, low platelets, birth weight, and neonatal seizures, consensus definitions were developed specifically for low- and middle-income countries because of the limited availability of diagnostic interventions including computerised tomography, chest x-ray, laboratory tests, equipment, and electroencephalogram monitoring. Conclusions: Consensus on measurements for the pre-eclampsia core outcome set will help to ensure consistency across future randomised trials and systematic reviews. Such standardization should make research evidence more accessible and facilitate the translation of research into clinical practice. Video abstract can be available at: www.dropbox.com/s/ftrgvrfu0u9glqd/6.%20Standardising%20definitions%20in%20teh%20pre-eclampsia%20core%20outcome%20set%3A%20a%20consensus%20development%20study.mp4?dl=0. Nuffield Department of Primary Care Health Sciences University of Oxford Institute for Women’s Health University College London Department of Women and Children’s Health School of Life Course Sciences King’s College London Department of Obstetrics and Gynecology Amsterdam UMC Academic Medical Center Academic Neonatal Medicine Imperial College London Department of Renal Medicine St George Hospital and University of New South Wales Department of Obstetrics and Gynaecology Feinberg School of Medicine Northwestern University Health Services Research Unit Nuffield Department of Population Health University of Oxford Cedars-Sinai Medical Center London North West University Healthcare NHS Trust Women’s Health Care Research Group Department of Obstetrics and Gynaecology Monash University Department of Obstetrics and Gynaecology University of Adelaide Women’s Health Research Unit Barts and The London School of Medicine and Dentistry School of Health and Related Research University of Sheffield MRC North West Hub for Trials Methodology Research Department of Biostatistics University of Liverpool Centro Rosarino de Estudios Perinatales Chelsea and Westminster Hospital NHS Foundation Trust Babcock University Ailem Academic Counselling KU Leuven Universidad Nacional de Colombia Northwell Health University of Oxford Université de Montréal University of Montreal Hospital Centre Ondokuz Mayıs University Prince Sultan Military Medical City Postgraduate Institute of Medical Education and Research King's Fertility Fetal Medicine Research Institute University Hospital Limerick Drexel University University of Aberdeen University of Groningen University of Auckland Haaglanden Medisch Centrum Nottingham University Medical School Utrecht University King Edward Memorial Hospital for Women Imperial College Healthcare NHS Trust Jean-Verdier Hospital Downland Practice University of Campinas Université Lyon University of North Carolina School of Medicine South Ural State Medical University Stellenbosch University Irish Neonatal Health Alliance University of Rzeszow Royal Brisbane and Women’s Hospital Nottingham University Hospitals NHS Trust University Hospitals of Leicester North Bristol NHS Trust University of Nottingham Soroka University Medical Center Ben Gurion University of the Negev St George’s University Hospitals NHS Foundation Trust Hospitalsenhed Midt University of Glasgow Amsterdam Universitair Medische Centra All India Institute of Medical Sciences Patna Luton and Dunstable University Hospital Khyber Medical University Institution of Medical Sciences Midwife Mid Essex Hospitals NHS Trust University of Oulu University of Michigan Bastyr University Irish Nurses and Midwives Organisation University of Toronto Barts Health NHS Trust University Hospitals Plymouth NHS Trust Burnet Institute Aga Khan University Medical University of Graz Homerton University Hospital NHS Foundation Trust Mount Royal University Université de Paris Royal Surrey County Hospital University Hospital Southampton NHS Foundation Trust University of Washington School of Nursing Evelina London Children's Hospital Neonatal Unit University of Sydney University of Leicester Academic Hospital of Udine NHS Borders Weill Cornell Medical College University of Dundee University of Edinburgh South Australian Health and Medical Research Institute University of Sheffield Monash University and Monash Health United Lincolnshire Hospitals NHS Trust University of Kwa Zulu-Natal Beatrix Hospital Keele University Government Medical College Institut Catala de la Salut. IdiapJgol University College London National Center for Child Health and Development Basavatarakam Indo-American Cancer Hospital and Research Institute Axon Anaesthesia Associates Pennine Acute Hospitals NHS Trust St George's University of London Norfolk and Norwich University Hospital Jichi Medical University School of Medicine São Paulo State University National Institute of Public Health University of Kyrenia King Edward Memorial Hospital Amsterdam University Centres University of British Columbia Chulalongkorn University University of Brescia University Of British Columbia University of Montreal Women's Clinic of Tartu University Hospital Universidade Federal de São Paulo Université de Sherbrooke University Hospital of Wales University of Iowa King's College London Westmead Hospital Princess Royal Maternity Leipzig University Centre Hospitalier Public du Cotentin Lewisham and Greenwich NHS Trust Juntendo University Faculty of Medicine Western Sydney University National Institute of Health Research University of Washington Baylor College of Medicine Capelle aan den Ijssel Sanatorio Anchorena Oxford University Hospitals NHS Foundation Trust University of Leeds Institute of Medical Sciences UPMC Magee Womens Hospital Penn Medicine Princeton Health University of North Carolina at Chapel Hill São Paulo State University
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- 2020
6. Viewing the body after bereavement due to a traumatic death: qualitative study in the UK
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Chapple, A and Ziebland, S
- Published
- 2010
7. Health inequalities, ethnic minorities and COVID19: interactive theatre workshop drawing on a qualitative interview study
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Dowrick, A, Rai, T, Hinton, L, Eacott, B, Baker, S, Askew, M, Ziebland, S, and Locock, L
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General Medicine - Published
- 2022
8. What People Close to Death Say about Euthanasia and Assisted Suicide: A Qualitative Study
- Author
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Chapple, A., Ziebland, S., McPherson, A., and Herxheimer, A.
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- 2006
- Full Text
- View/download PDF
9. Stigma, shame, and blame experienced by patients with lung cancer: qualitative study
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Chapple, A, Ziebland, S, and McPherson, A
- Published
- 2004
10. Does Stage of Change predict outcome in a primary-care intervention to encourage an increase in fruit and vegetable consumption?
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John, J. H., Yudkin, P. L., Neil, H. A. W., and Ziebland, S.
- Published
- 2003
11. Development and validation of the Day in the Life Questionnaire (DILQ) as a measure of fruit and vegetable questionnaire for 7–9 year olds
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Edmunds, L. D. and Ziebland, S.
- Published
- 2002
12. A systematic review of reasons for and against asking patients about their socioeconomic contexts
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Moscrop, A, Ziebland, S, Roberts, N, and Papanikitas, A
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medicine.medical_specialty ,Population ,Population health ,Disclosure ,Socioeconomic factors ,Health Services Accessibility ,03 medical and health sciences ,Social determinants of health ,Health care ,medicine ,Humans ,education ,Socioeconomic status ,Health policy ,education.field_of_study ,Medical records ,030505 public health ,business.industry ,Health Policy ,Public health ,lcsh:Public aspects of medicine ,Public Health, Environmental and Occupational Health ,Health services research ,Reproducibility of Results ,lcsh:RA1-1270 ,Professional-Patient Relations ,Health Services ,Family medicine ,Systematic Review ,0305 other medical science ,Psychology ,business ,Delivery of Health Care ,Confidentiality - Abstract
Background People’s social and economic circumstances are important determinants of their health, health experiences, healthcare access, and healthcare outcomes. However, patients’ socioeconomic circumstances are rarely asked about or documented in healthcare settings. We conducted a systematic review of published reasons for why patients’ socioeconomic contexts (including education, employment, occupation, housing, income, or wealth) should, or should not, be enquired about. Methods Systematic review of literature published up to and including 2016. A structured literature search using databases of medicine and nursing (pubmed, embase, global health), ethics (Ethicsweb), social sciences (Web of Science), and psychology (PsychINFO) was followed by a ‘snowball’ search. Eligible publications contained one or more reasons for: asking patients about socioeconomic circumstances; collecting patients’ socioeconomic information; ‘screening’ patients for adverse socioeconomic circumstances; or linking other sources of individual socioeconomic data to patients’ healthcare records. Two authors conducted the screening: the first screened all references, the second author screened a 20% sample with inter-rater reliability statistically confirmed. ‘Reason data’ was extracted from eligible publications by two authors, then analysed and organised. Results We identified 138 eligible publications. Most offered reasons for why patients’ should be asked about their socioeconomic circumstances. Reasons included potential improvements in: individual healthcare outcomes; healthcare service monitoring and provision; population health research and policies. Many authors also expressed concerns for improving equity in health. Eight publications suggested patients should not be asked about their socioeconomic circumstances, due to: potential harms; professional boundaries; and the information obtained being inaccurate or unnecessary. Conclusions This first summary of literature on the subject found many published reasons for why patients’ social and economic circumstances should be enquired about in healthcare settings. These reasons include potential benefits at the levels of individuals, health service provision, and population, as well as the potential to improve healthcare equity. Cautions and caveats include concerns about the clinician’s role in responding to patients’ social problems; the perceived importance of social health determinants compared with biomedical factors; the use of average population data from geographic areas to infer the socioeconomic experience of individuals. Actual evidence of outcomes is lacking: our review suggests hypotheses that can be tested in future research.
- Published
- 2019
13. A core outcome set for pre-eclampsia research: an international consensus development study.
- Author
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Ghosh S.K., Daly M.C., Darmochwal-Kolarz D.A., Davies R.E., Davies M.W., Dawson J.S., Dobson N., Dodd C.N., Donald F., Duley L., Epstein-Mares J., Erez O., Evans E., Farlie R.N., Ferris A.V., Frankland E.M., Freeman D.J., Gainder S., Ganzevoort W., Hamilton L.M., Hammond S.J., Harlow S.D., Hays K.E., Hickey S.C., Higgins M., Hinton L., Hobson S.R., Hogg M.J., Hollands H.J., EH C.S.E., Hoodbhoy Z., Howell P., Huppertz B., Husain S., Jacoby S.D., Jacqz-Aigrain E., Jenkins G., Jewel D., Johnson M.J., Johnston C.L., Jones P.M., Kantrowitz-Gordon I., Khan R.-U., Kirby L.J., Kirk C., Knight M., Korey M.T., Lee G.J., Lee V.W., Levene L.S., Londero A.P., Lust K.M., MacKenzie V., Malha L., Mattone M., McCartney D.E., McFadden A., McKinstry B.H., Middleton P.F., Mistry H.D., Mitchell C.A., Mockler J.C., Molsher S.-A., Monast E.S., Moodley E.J., Mooij R., Moore E.L., Morgan L., Moulson A., Mughal F., Mundle S.R., Munoz M.A., Murray E., Nagata C., Nair A.S., Nakimuli A., Nath G., Newport R.S., Oakeshott P., Ochoa-Ferraro M.R., Odendaal H., Ohkuchi A., Oliveira L., Ortiz-Panozo E., Oudijk M.A., Oygucu S.E., Paech M.J., Painter R.C., Parry C.L., Payne B.A., Pearson E.L., Phupong V., Pickett N., Pickles K.A., Plumb L.K., Prefumo F., Preston R., Ray J.G., Rayment J., Regan L.V., Rey E., Robson E.J., Rubin A.N., Rubio-Romero A.N., Rull K., Sass N., Sauve N., Savory N.A., Scott J.R., Seaton S.E., Seed P.T., Shakespeare J.M., Shand A.W., Sharma S., Shaw T.Y., Smedley K.L., Smith D., Conk A.S., Soward D., Stepan H., Stroumpoulis K., SurenDr A., Takeda S., Tan L., Theriot B.S., Thomas H.F., Thompson K., Thompson P.I., Thompson M.J., Toms L., Torney K.L.H.T., Treadwell J.S., Tucker K.L., Turrentine M.A., Van Hecke O., Van Oostwaard M.F., Vasquez D.N., AV D.J.A., VInturache A., Walker J., Wardle S.P., Wasim T., Waters J.H., Whitehead C.L., Wolfson A., Yeo S., Duffy J.M.N., Cairns A.E., Richards-Doran D., van 't Hooft J., Gale C., Brown M., Chappell L.C., Grobman W.A., Fitzpatrick R., Karumanchi S.A., Khalil A., Lucas D.N., Magee L.A., Mol B.W., Stark M., Thangaratinam S., Wilson M.J., von Dadelszen P., Williamson P.R., Ziebland S., McManus R.J., Abalos E.J., DA C.C.D., AkaDr A.A., Akturk Z., Allegaert K., Angel-Muller E., Antretter J., Ashdown H.F., Audibert F., Auger N., Aygun C., Babic I., Bagga R., Baker J.M., Bhakta P., Bhandari V., Bhattacharya S., Blanker M.H., Bloomfield F.H., Bof A., Brennan S.M., Broekhuijsen K., Pipkin E.F.B., Browne J.L., Browning R.M., Bull J.W., Butt A., Button D., Campbell J.P., Campbell D.M., Carbillon L., Carthy S., Casely E., Cave J.A., Cecatti J.G., Chamillard M.E., Chassard D., Checheir N.C., Chulkov V.S., Cluver C.A., Crawford C.F., Gbinigie O.A., Glogowska M., Goodlife A., Gough K.L., Green J.R., Gul F., Haggerty L., Hall D.R., Hallman M., Ghosh S.K., Daly M.C., Darmochwal-Kolarz D.A., Davies R.E., Davies M.W., Dawson J.S., Dobson N., Dodd C.N., Donald F., Duley L., Epstein-Mares J., Erez O., Evans E., Farlie R.N., Ferris A.V., Frankland E.M., Freeman D.J., Gainder S., Ganzevoort W., Hamilton L.M., Hammond S.J., Harlow S.D., Hays K.E., Hickey S.C., Higgins M., Hinton L., Hobson S.R., Hogg M.J., Hollands H.J., EH C.S.E., Hoodbhoy Z., Howell P., Huppertz B., Husain S., Jacoby S.D., Jacqz-Aigrain E., Jenkins G., Jewel D., Johnson M.J., Johnston C.L., Jones P.M., Kantrowitz-Gordon I., Khan R.-U., Kirby L.J., Kirk C., Knight M., Korey M.T., Lee G.J., Lee V.W., Levene L.S., Londero A.P., Lust K.M., MacKenzie V., Malha L., Mattone M., McCartney D.E., McFadden A., McKinstry B.H., Middleton P.F., Mistry H.D., Mitchell C.A., Mockler J.C., Molsher S.-A., Monast E.S., Moodley E.J., Mooij R., Moore E.L., Morgan L., Moulson A., Mughal F., Mundle S.R., Munoz M.A., Murray E., Nagata C., Nair A.S., Nakimuli A., Nath G., Newport R.S., Oakeshott P., Ochoa-Ferraro M.R., Odendaal H., Ohkuchi A., Oliveira L., Ortiz-Panozo E., Oudijk M.A., Oygucu S.E., Paech M.J., Painter R.C., Parry C.L., Payne B.A., Pearson E.L., Phupong V., Pickett N., Pickles K.A., Plumb L.K., Prefumo F., Preston R., Ray J.G., Rayment J., Regan L.V., Rey E., Robson E.J., Rubin A.N., Rubio-Romero A.N., Rull K., Sass N., Sauve N., Savory N.A., Scott J.R., Seaton S.E., Seed P.T., Shakespeare J.M., Shand A.W., Sharma S., Shaw T.Y., Smedley K.L., Smith D., Conk A.S., Soward D., Stepan H., Stroumpoulis K., SurenDr A., Takeda S., Tan L., Theriot B.S., Thomas H.F., Thompson K., Thompson P.I., Thompson M.J., Toms L., Torney K.L.H.T., Treadwell J.S., Tucker K.L., Turrentine M.A., Van Hecke O., Van Oostwaard M.F., Vasquez D.N., AV D.J.A., VInturache A., Walker J., Wardle S.P., Wasim T., Waters J.H., Whitehead C.L., Wolfson A., Yeo S., Duffy J.M.N., Cairns A.E., Richards-Doran D., van 't Hooft J., Gale C., Brown M., Chappell L.C., Grobman W.A., Fitzpatrick R., Karumanchi S.A., Khalil A., Lucas D.N., Magee L.A., Mol B.W., Stark M., Thangaratinam S., Wilson M.J., von Dadelszen P., Williamson P.R., Ziebland S., McManus R.J., Abalos E.J., DA C.C.D., AkaDr A.A., Akturk Z., Allegaert K., Angel-Muller E., Antretter J., Ashdown H.F., Audibert F., Auger N., Aygun C., Babic I., Bagga R., Baker J.M., Bhakta P., Bhandari V., Bhattacharya S., Blanker M.H., Bloomfield F.H., Bof A., Brennan S.M., Broekhuijsen K., Pipkin E.F.B., Browne J.L., Browning R.M., Bull J.W., Butt A., Button D., Campbell J.P., Campbell D.M., Carbillon L., Carthy S., Casely E., Cave J.A., Cecatti J.G., Chamillard M.E., Chassard D., Checheir N.C., Chulkov V.S., Cluver C.A., Crawford C.F., Gbinigie O.A., Glogowska M., Goodlife A., Gough K.L., Green J.R., Gul F., Haggerty L., Hall D.R., and Hallman M.
- Abstract
Objective: To develop a core outcome set for pre-eclampsia. Design(s): Consensus development study. Setting(s): International. Population: Two hundred and eight-one healthcare professionals, 41 researchers and 110 patients, representing 56 countries, participated. Method(s): Modified Delphi method and Modified Nominal Group Technique. Result(s): A long-list of 116 potential core outcomes was developed by combining the outcomes reported in 79 pre-eclampsia trials with those derived from thematic analysis of 30 in-depth interviews of women with lived experience of pre-eclampsia. Forty-seven consensus outcomes were identified from the Delphi process following which 14 maternal and eight offspring core outcomes were agreed at the consensus development meeting. Maternal core outcomes: death, eclampsia, stroke, cortical blindness, retinal detachment, pulmonary oedema, acute kidney injury, liver haematoma or rupture, abruption, postpartum haemorrhage, raised liver enzymes, low platelets, admission to intensive care required, and intubation and ventilation. Offspring core outcomes: stillbirth, gestational age at delivery, birthweight, small-for-gestational-age, neonatal mortality, seizures, admission to neonatal unit required and respiratory support. Conclusion(s): The core outcome set for pre-eclampsia should underpin future randomised trials and systematic reviews. Such implementation should ensure that future research holds the necessary reach and relevance to inform clinical practice, enhance women's care and improve the outcomes of pregnant women and their babies. Tweetable abstract: 281 healthcare professionals, 41 researchers and 110 women have developed #preeclampsia core outcomes @HOPEoutcomes @jamesmnduffy. [Correction added on 29 June 2020, after first online publication: the order has been corrected.].Copyright © 2020 The Authors. BJOG: An International Journal of Obstetrics and Gynaecology published by John Wiley & Sons Ltd on behalf of Royal College of Obstetr
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- 2021
14. What outcomes should researchers select, collect and report in pre-eclampsia research? A qualitative study exploring the views of women with lived experience of pre-eclampsia
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Duffy, Jmn, Thompson, T, Hinton, L, Salinas, M, McManus, RJ, Ziebland, S, International Collaboration to Harmonise Outcomes in Pre-eclampsia (iHOPE) Qualitative Research Group, Hinton, Lisa [0000-0002-6082-3151], and Apollo - University of Cambridge Repository
- Subjects
Adult ,pre-eclampsia ,outcomes ,female genital diseases and pregnancy complications ,United Kingdom ,Treatment Outcome ,Pregnancy ,Research Design ,embryonic structures ,Outcome Assessment, Health Care ,Core outcome sets ,Humans ,in-depth patient interviews ,Female ,Patient Reported Outcome Measures ,reproductive and urinary physiology ,Qualitative Research - Abstract
OBJECTIVE: To identify outcomes relevant to women with lived experience of pre-eclampsia. DESIGN: Qualitative interview study. SETTING: A national study conducted in the United Kingdom. SAMPLE: Purposive sample of women with lived experience of pre-eclampsia. METHODS: Thematic analysis of qualitative interview transcripts. RESULTS: Thirty women with lived experience of pre-eclampsia were interviewed. Thematic analysis identified 71 different treatment outcomes. Fifty-nine of these had been previously reported by pre-eclampsia trials. Outcomes related to maternal and neonatal morbidity, commonly reported by pre-eclampsia trials, were frequently discussed by women with lived experience of pre-eclampsia. Twelve outcomes had not been previously reported by pre-eclampsia trials. When compared with published research, it was evident that the outlook of women with lived experience of pre-eclampsia was broader. They considered pre-eclampsia in relation to the 'whole' person and attached special significance to outcomes relating to emotional wellbeing and the future health, development and wellbeing of their offspring. CONCLUSIONS: Selecting, collecting and reporting outcomes relevant to women with pre-eclampsia should ensure that future pre-eclampsia research has the necessary reach and relevance to inform clinical practice. Future core outcome set development studies should use qualitative research methods to ensure that the long list of potential core outcomes holds relevance to patients. TWEETABLE ABSTRACT: What do women want? A national study identifies key treatment outcomes for women with pre-eclampsia. Next step: @coreoutcomes for #preeclampsia @NIHR_DC.
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- 2020
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15. ‘I Can Be The Me I Want To Be By Taking an Antidepressant Regularly’: People’s Feelings About Taking Antidepressants
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Anderson, C., Kirkpatrick, S., Avery, A., and Ziebland, S.
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- 2014
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16. A core outcome set for pre‐eclampsia research : an international consensus development study
- Author
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Duffy, JMN, Cairns, AE, Richards‐Doran, D, van 't Hooft, J, Gale, C, Brown, M, Chappell, LC, Grobman, WA, Fitzpatrick, R, Karumanchi, SA, Khalil, A, Lucas, DN, Magee, LA, Mol, BW, Stark, M, Thangaratinam, S, Wilson, MJ, von Dadelszen, P, Williamson, PR, Ziebland, S, McManus, RJ, Abalos, EJ, Adamson, CCD, Akadri, AA, Akturk, Z, Allegaert, K, Angel‐Müller, E, Antretter, J, Audibert, F, Auger, N, Aygun, C, Babic, I, Bagga, R, Baker, JM, Bhandari, V, Bhattacharya, S, Blanker, MH, Bloomfield, FH, Bof, A, Brennan, SM, Broekhuijsen, K, Fiona Broughton Pipkin, E, Browne, JL, Browning, RM, Bull, JW, Butt, A, Button, D, Campbell, JP, Campbell, DM, Carbillon, L, Carthy, S, Casely, E, Cave, JA, Cecatti, JG, Chamillard, ME, Chassard, D, Checheir, NC, Chulkov, VS, Cluver, CA, Crawford, CF, Daly, MC, Darmochwal‐Kolarz, DA, Davies, RE, Davies, MW, Dawson, JS, Dobson, N, Dodd, CN, Donald, F, Duley, L, Epstein‐Mares, J, Erez, O, Evans, E, Farlie, RN, Ferris, AV, Frankland, EM, Freeman, DJ, Gainder, S, Ganzevoort, W, Gbinigie, OA, Ghosh, SK, Glogowska, M, Goodlife, A, Gough, KL, Green, JR, Gul, F, Haggerty, L, Hall, DR, Hallman, M, Hammond, SJ, Harlow, SD, Hays, KE, Hickey, SC, Higgins, M, Hinton, L, Hobson, SR, Hogg, MJ, Hollands, HJ, Homer, CSE, Hoodbhoy, Z, Howell, P, Huppertz, B, Husain, S, Jacoby, SD, Jacqz‐Aigrain, E, Jenkins, G, Jewel, D, Johnson, MJ, Johnston, CL, Jones, PM, Kantrowitz‐Gordon, I, Khan, R, Kirby, LJ, Kirk, C, Knight, M, Korey, MT, Lee, GJ, Lee, VW, Levene, LS, Londero, AP, Lust, KM, MacKenzie, V, Malha, L, Mattone, M, McCartney, DE, McFadden, A, McKinstry, BH, Middleton, PF, Mistry, HD, Mitchell, CA, Mockler, JC, Molsher, S, Monast, ES, Moodley, J, Mooij, R, Moore, EL, Morgan, L, Moulson, A, Mughal, F, Mundle, SR, Angel Munoz, M, Murray, E, Nagata, C, Nair, AS, Nakimuli, A, Nath, G, Newport, RS, Oakeshott, P, Ochoa‐Ferraro, MR, Odendaal, H, Ohkuchi, A, Oliveira, L, Ortiz‐Panozo, E, Oudijk, MA, Oygucu, SE, Paech, MJ, Painter, RC, Parry, CL, Payne, BA, Pearson, EL, Phupong, V, Pickett, N, Pickles, KA, Plumb, LK, Prefumo, F, Preston, R, Ray, JG, Rayment, J, Regan, LV, Rey, E, Robson, EJ, Rubin, AN, Rubio‐Romero, JA, Rull, K, Sass, N, Sauvé, N, Savory, NA, Scott, JR, Seaton, SE, Seed, PT, Shakespeare, JM, Shand, AW, Sharma, S, Shaw, TY, Smedley, KL, Smith, D, Smith Conk, A, Soward, D, Stepan, H, Stroumpoulis, K, Surendran, A, Takeda, S, Tan, L, Theriot, BS, Thomas, HF, Thompson, K, Thompson, PI, Thompson, MJ, Torney, KLHT, Treadwell, JS, Tucker, KL, Turrentine, MA, Van Hecke, O, Van Oostwaard, MF, Vasquez, DN, Vaughan, DJA, VInturache, A, Walker, J, Wardle, SP, Wasim, T, Waters, JH, Whitehead, CL, Wolfson, A, Yeo, S, and Zermansky, AG
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reproductive and urinary physiology - Abstract
Objective\ud To develop a core outcome set for pre‐eclampsia.\ud \ud Design\ud Consensus development study.\ud \ud Setting\ud International.\ud \ud Population\ud Two hundred and eight‐one healthcare professionals, 41 researchers and 110 patients, representing 56 countries, participated.\ud \ud Methods\ud Modified Delphi method and Modified Nominal Group Technique.\ud \ud Results\ud A long‐list of 116 potential core outcomes was developed by combining the outcomes reported in 79 pre‐eclampsia trials with those derived from thematic analysis of 30 in‐depth interviews of women with lived experience of pre‐eclampsia. Forty‐seven consensus outcomes were identified from the Delphi process following which 14 maternal and eight offspring core outcomes were agreed at the consensus development meeting. Maternal core outcomes: death, eclampsia, stroke, cortical blindness, retinal detachment, pulmonary oedema, acute kidney injury, liver haematoma or rupture, abruption, postpartum haemorrhage, raised liver enzymes, low platelets, admission to intensive care required, and intubation and ventilation. Offspring core outcomes: stillbirth, gestational age at delivery, birthweight, small‐for‐gestational‐age, neonatal mortality, seizures, admission to neonatal unit required and respiratory support.\ud \ud Conclusions\ud The core outcome set for pre‐eclampsia should underpin future randomised trials and systematic reviews. Such implementation should ensure that future research holds the necessary reach and relevance to inform clinical practice, enhance women's care and improve the outcomes of pregnant women and their babies.
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- 2020
17. Standardising definitions for the pre-eclampsia core outcome set: A consensus development study.
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Donald F., Morgan L., Moulson A., Mughal F., Mundle S.R., Munoz M.A., Murray E., Nagata C., Nair A.S., Nakimuli A., Nath G., Newport R.S., Oakeshott P., Ochoa-Ferraro M.R., Odendaal H., Ohkuchi A., Oliveira L., Ortiz-Panozo E., Oudijk M.A., Oygucu S.E., Paech M.J., Painter R.C., Parry C.L., Payne B.A., Pearson E.L., Phupong V., Pickett N., Pickles K.A., Plumb L.K., Prefumo F., Preston R., Ray J.G., Rayment J., Regan L.V., Rey E., Robson E.J., Rubin A.N., Rubio-Romero J.A., Rull K., Sass N., Sauve N., Savory N.A., Scott J.R., Seaton S.E., Seed P.T., Shakespeare J.M., Shand A.W., Sharma S., Shaw T.Y., Smedley K.L., Smith D., Smith Conk A., Soward D., Stepan H., Stroumpoulis K., Surendran A., Takeda S., Tan L., Theriot B.S., Thomas H.F., Thompson K., Thompson P.I., Thompson M.J., Toms L., Torney K.L.H.T., Treadwell J.S., Tucker K.L., Turrentine M.A., Van Hecke O., Van Oostwaard M.F., Vasquez D.N., Vaughan D.J.A., Vinturache A., Walker J., Wardle S.P., Wasim T., Waters J.H., Whitehead C.L., Wolfson A., Yeo S., Zermansky A.G., Mol B., Duffy J.M.N., Cairns A.E., Magee L.A., von Dadelszen P., van 't Hooft J., Gale C., Brown M., Chappell L.C., Grobman W.A., Fitzpatrick R., Karumanchi S.A., Lucas D.N., Stark M., Thangaratinam S., Wilson M.J., Williamson P.R., Ziebland S., McManus R.J., Abalos E.J., Adamson C.C.D., Akadri A.A., Akturk Z., Allegaert K., Angel-Muller E., Antretter J., Ashdown H.F., Audibert F., Auger N., Aygun C., Babic I., Bagga R., Baker J.M., Beebeejaun Y., Bhakta P., Bhandari V., Bhattacharya S., Blanker M.H., Bloomfield F.H., Bof A., Brennan S.M., Broekhuijsen K., Broughton Pipkin F., Browne J.L., Browning R.M., Bull J.W., Butt A., Button D., Campbell J.P., Campbell D.M., Carbillon L., Carthy S., Casely E., Cave J.A., Cecatti J.G., Chamillard M.E., Chassard D., Checheir N.C., Chulkov V.S., Cluver C.A., Crawford C.F., Daly M.C., Darmochwal-Kolarz D.A., Davies R.E., Davies M.W., Dawson J.S., Dobson N., Dodd C.N., Duley L., Epstein-Mares J., Erez O., Evans E., Farlie R.N., Ferris A.V., Frankland E.M., Freeman D.J., Gainder S., Ganzevoort W., Gbinigie O.A., Gerval M.-O., Ghosh S.K., Gingel L.J., Glogowska M., Goodlife A., Gough K.L., Green J.R., Gul F., Haggerty L., Hall D.R., Hallman M., Hamilton L.M., Hammond S.J., Harlow S.D., Hays K.E., Hickey S.C., Higgins M., Hinton L., Hobson S.R., Hogg M.J., Hollands H.J., Homer C.S.E., Hoodbhoy Z., Howell P., Huppertz B., Husain S., Jacoby S.D., Jacqz-Aigrain E., Jenkins G., Jewel D., Johnson M.J., Johnston C.L., Jones P.M., Kantrowitz-Gordon I., Khan R.-U., Kirby L.J., Kirk C., Knight M., Korey M.T., Lee G.J., Lee V.W., Levene L.S., Londero A.P., Lust K.M., MacKenzie V., Malha L., Mattone M., McCartney D.E., McFadden A., McKinstry B.H., Middleton P.F., Mills D.J., Mistry H.D., Mitchell C.A., Mockler J.C., Molsher S.-A., Monast E.S., Moodley J., Mooij R., Moore E.L., Donald F., Morgan L., Moulson A., Mughal F., Mundle S.R., Munoz M.A., Murray E., Nagata C., Nair A.S., Nakimuli A., Nath G., Newport R.S., Oakeshott P., Ochoa-Ferraro M.R., Odendaal H., Ohkuchi A., Oliveira L., Ortiz-Panozo E., Oudijk M.A., Oygucu S.E., Paech M.J., Painter R.C., Parry C.L., Payne B.A., Pearson E.L., Phupong V., Pickett N., Pickles K.A., Plumb L.K., Prefumo F., Preston R., Ray J.G., Rayment J., Regan L.V., Rey E., Robson E.J., Rubin A.N., Rubio-Romero J.A., Rull K., Sass N., Sauve N., Savory N.A., Scott J.R., Seaton S.E., Seed P.T., Shakespeare J.M., Shand A.W., Sharma S., Shaw T.Y., Smedley K.L., Smith D., Smith Conk A., Soward D., Stepan H., Stroumpoulis K., Surendran A., Takeda S., Tan L., Theriot B.S., Thomas H.F., Thompson K., Thompson P.I., Thompson M.J., Toms L., Torney K.L.H.T., Treadwell J.S., Tucker K.L., Turrentine M.A., Van Hecke O., Van Oostwaard M.F., Vasquez D.N., Vaughan D.J.A., Vinturache A., Walker J., Wardle S.P., Wasim T., Waters J.H., Whitehead C.L., Wolfson A., Yeo S., Zermansky A.G., Mol B., Duffy J.M.N., Cairns A.E., Magee L.A., von Dadelszen P., van 't Hooft J., Gale C., Brown M., Chappell L.C., Grobman W.A., Fitzpatrick R., Karumanchi S.A., Lucas D.N., Stark M., Thangaratinam S., Wilson M.J., Williamson P.R., Ziebland S., McManus R.J., Abalos E.J., Adamson C.C.D., Akadri A.A., Akturk Z., Allegaert K., Angel-Muller E., Antretter J., Ashdown H.F., Audibert F., Auger N., Aygun C., Babic I., Bagga R., Baker J.M., Beebeejaun Y., Bhakta P., Bhandari V., Bhattacharya S., Blanker M.H., Bloomfield F.H., Bof A., Brennan S.M., Broekhuijsen K., Broughton Pipkin F., Browne J.L., Browning R.M., Bull J.W., Butt A., Button D., Campbell J.P., Campbell D.M., Carbillon L., Carthy S., Casely E., Cave J.A., Cecatti J.G., Chamillard M.E., Chassard D., Checheir N.C., Chulkov V.S., Cluver C.A., Crawford C.F., Daly M.C., Darmochwal-Kolarz D.A., Davies R.E., Davies M.W., Dawson J.S., Dobson N., Dodd C.N., Duley L., Epstein-Mares J., Erez O., Evans E., Farlie R.N., Ferris A.V., Frankland E.M., Freeman D.J., Gainder S., Ganzevoort W., Gbinigie O.A., Gerval M.-O., Ghosh S.K., Gingel L.J., Glogowska M., Goodlife A., Gough K.L., Green J.R., Gul F., Haggerty L., Hall D.R., Hallman M., Hamilton L.M., Hammond S.J., Harlow S.D., Hays K.E., Hickey S.C., Higgins M., Hinton L., Hobson S.R., Hogg M.J., Hollands H.J., Homer C.S.E., Hoodbhoy Z., Howell P., Huppertz B., Husain S., Jacoby S.D., Jacqz-Aigrain E., Jenkins G., Jewel D., Johnson M.J., Johnston C.L., Jones P.M., Kantrowitz-Gordon I., Khan R.-U., Kirby L.J., Kirk C., Knight M., Korey M.T., Lee G.J., Lee V.W., Levene L.S., Londero A.P., Lust K.M., MacKenzie V., Malha L., Mattone M., McCartney D.E., McFadden A., McKinstry B.H., Middleton P.F., Mills D.J., Mistry H.D., Mitchell C.A., Mockler J.C., Molsher S.-A., Monast E.S., Moodley J., Mooij R., and Moore E.L.
- Abstract
Objectives: To develop consensus definitions for the core outcome set for pre-eclampsia. Study design: Potential definitions for individual core outcomes were identified across four formal definition development initiatives, nine national and international guidelines, 12 Cochrane systematic reviews, and 79 randomised trials. Eighty-six definitions were entered into the consensus development meeting. Ten healthcare professionals and three researchers, including six participants who had experience of conducting research in low- and middle-income countries, participated in the consensus development process. The final core outcome set was approved by an international steering group. Result(s): Consensus definitions were developed for all core outcomes. When considering stroke, pulmonary oedema, acute kidney injury, raised liver enzymes, low platelets, birth weight, and neonatal seizures, consensus definitions were developed specifically for low- and middle-income countries because of the limited availability of diagnostic interventions including computerised tomography, chest x-ray, laboratory tests, equipment, and electroencephalogram monitoring. Conclusion(s): Consensus on measurements for the pre-eclampsia core outcome set will help to ensure consistency across future randomised trials and systematic reviews. Such standardization should make research evidence more accessible and facilitate the translation of research into clinical practice. Video abstract can be available at: www.dropbox.com/s/ftrgvrfu0u9glqd/6.%20Standardising%20definitions%20in%20teh%20pre-eclampsia%20core%20outcome%20set%3A%20a%20consensus%20development%20study.mp4?dl=0.Copyright © 2020 International Society for the Study of Hypertension in Pregnancy
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- 2020
18. A core outcome set for pre-eclampsia research:an international consensus development study
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Duffy, J. M.N., Cairns, A. E., Richards-Doran, D., van 't Hooft, J., Gale, C., Brown, M., Chappell, L. C., Grobman, W. A., Fitzpatrick, R., Karumanchi, S. A., Khalil, A., Lucas, D. N., Magee, L. A., Mol, B. W., Stark, M., Thangaratinam, S., Wilson, M. J., von Dadelszen, P., Williamson, P. R., Ziebland, S., McManus, R. J., Abalos, Edgardo J., DA, Christine C.D., AkaDr, Adebayo A., Akturk, Zekeriya, Allegaert, Karel, Angel-Müller, Edith, Antretter, Jessica, Ashdown, Helen F., Audibert, Francois, Auger, Nathalie, Aygun, Canan, Babic, Inas, Bagga, Rashmi, Baker, Judith M., Bhakta, Pradipta, Bhandari, Vineet, Bhattacharya, Sohinee, Blanker, Marco H., Bloomfield, Frank H., Bof, Anna, Brennan, Siobhan M., Broekhuijsen, Kim, Pipkin, Emeritus Fiona Broughton, Browne, Joyce L., Browning, Roger M., Bull, Jameson W., Butt, Amina, Button, Dena, Van Oostwaard, Miriam F., Duffy, J. M.N., Cairns, A. E., Richards-Doran, D., van 't Hooft, J., Gale, C., Brown, M., Chappell, L. C., Grobman, W. A., Fitzpatrick, R., Karumanchi, S. A., Khalil, A., Lucas, D. N., Magee, L. A., Mol, B. W., Stark, M., Thangaratinam, S., Wilson, M. J., von Dadelszen, P., Williamson, P. R., Ziebland, S., McManus, R. J., Abalos, Edgardo J., DA, Christine C.D., AkaDr, Adebayo A., Akturk, Zekeriya, Allegaert, Karel, Angel-Müller, Edith, Antretter, Jessica, Ashdown, Helen F., Audibert, Francois, Auger, Nathalie, Aygun, Canan, Babic, Inas, Bagga, Rashmi, Baker, Judith M., Bhakta, Pradipta, Bhandari, Vineet, Bhattacharya, Sohinee, Blanker, Marco H., Bloomfield, Frank H., Bof, Anna, Brennan, Siobhan M., Broekhuijsen, Kim, Pipkin, Emeritus Fiona Broughton, Browne, Joyce L., Browning, Roger M., Bull, Jameson W., Butt, Amina, Button, Dena, and Van Oostwaard, Miriam F.
- Abstract
Objective: To develop a core outcome set for pre-eclampsia. Design: Consensus development study. Setting: International. Population: Two hundred and eight-one healthcare professionals, 41 researchers and 110 patients, representing 56 countries, participated. Methods: Modified Delphi method and Modified Nominal Group Technique. Results: A long-list of 116 potential core outcomes was developed by combining the outcomes reported in 79 pre-eclampsia trials with those derived from thematic analysis of 30 in-depth interviews of women with lived experience of pre-eclampsia. Forty-seven consensus outcomes were identified from the Delphi process following which 14 maternal and eight offspring core outcomes were agreed at the consensus development meeting. Maternal core outcomes: death, eclampsia, stroke, cortical blindness, retinal detachment, pulmonary oedema, acute kidney injury, liver haematoma or rupture, abruption, postpartum haemorrhage, raised liver enzymes, low platelets, admission to intensive care required, and intubation and ventilation. Offspring core outcomes: stillbirth, gestational age at delivery, birthweight, small-for-gestational-age, neonatal mortality, seizures, admission to neonatal unit required and respiratory support. Conclusions: The core outcome set for pre-eclampsia should underpin future randomised trials and systematic reviews. Such implementation should ensure that future research holds the necessary reach and relevance to inform clinical practice, enhance women's care and improve the outcomes of pregnant women and their babies. Tweetable abstract: 281 healthcare professionals, 41 researchers and 110 women have developed #preeclampsia core outcomes @HOPEoutcomes @jamesmnduffy. [Correction added on 29 June 2020, after first online publication: the order has been corrected.].
- Published
- 2020
19. Standardising definitions for the pre-eclampsia core outcome set: A consensus development study.
- Author
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Duffy, JMN, Cairns, AE, Magee, LA, von Dadelszen, P, van 't Hooft, J, Gale, C, Brown, M, Chappell, LC, Grobman, WA, Fitzpatrick, R, Karumanchi, SA, Lucas, DN, Mol, B, Stark, M, Thangaratinam, S, Wilson, MJ, Williamson, PR, Ziebland, S, McManus, RJ, International Collaboration to Harmonise Outcomes for Pre-eclampsia (iHOPE), Duffy, JMN, Cairns, AE, Magee, LA, von Dadelszen, P, van 't Hooft, J, Gale, C, Brown, M, Chappell, LC, Grobman, WA, Fitzpatrick, R, Karumanchi, SA, Lucas, DN, Mol, B, Stark, M, Thangaratinam, S, Wilson, MJ, Williamson, PR, Ziebland, S, McManus, RJ, and International Collaboration to Harmonise Outcomes for Pre-eclampsia (iHOPE)
- Abstract
OBJECTIVES: To develop consensus definitions for the core outcome set for pre-eclampsia. STUDY DESIGN: Potential definitions for individual core outcomes were identified across four formal definition development initiatives, nine national and international guidelines, 12 Cochrane systematic reviews, and 79 randomised trials. Eighty-six definitions were entered into the consensus development meeting. Ten healthcare professionals and three researchers, including six participants who had experience of conducting research in low- and middle-income countries, participated in the consensus development process. The final core outcome set was approved by an international steering group. RESULTS: Consensus definitions were developed for all core outcomes. When considering stroke, pulmonary oedema, acute kidney injury, raised liver enzymes, low platelets, birth weight, and neonatal seizures, consensus definitions were developed specifically for low- and middle-income countries because of the limited availability of diagnostic interventions including computerised tomography, chest x-ray, laboratory tests, equipment, and electroencephalogram monitoring. CONCLUSIONS: Consensus on measurements for the pre-eclampsia core outcome set will help to ensure consistency across future randomised trials and systematic reviews. Such standardization should make research evidence more accessible and facilitate the translation of research into clinical practice. Video abstract can be available at: www.dropbox.com/s/ftrgvrfu0u9glqd/6.%20Standardising%20definitions%20in%20teh%20pre-eclampsia%20core%20outcome%20set%3A%20a%20consensus%20development%20study.mp4?dl=0.
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- 2020
20. Methodological decisions influence the identification of potential core outcomes in studies related to pre-eclampsia: an analysis informing the development of recommendations for future core outcome set developers
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Duffy, JMN, Hirsch, M, Ziebland, S, McManus, RJ, Duffy, James MN, Brown, Mark, Gale, Chris, Grobman, William, Fitzpatrick, Ray, Karumanchi, S Ananth, Lucas, Nuala, Magee, Laura, Mol, Ben, Stark, Michael, Thangaratinam, Shakila, Wilson, Mathew, Hooft, Janneke van't, von Dadelszen, Peter, Williamson, Paula R, Khan, Khalid S, Ziebland, Sue, McManus, Richard J, and Outcom, Int Collaboration Harmonise
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Medical education ,030219 obstetrics & reproductive medicine ,business.industry ,Obstetrics and Gynecology ,Sample (statistics) ,Outcome (game theory) ,Child health ,Decision Support Techniques ,03 medical and health sciences ,Identification (information) ,Core (game theory) ,0302 clinical medicine ,Pre-Eclampsia ,Pregnancy ,Prenatal Diagnosis ,Outcome Assessment, Health Care ,Humans ,Medicine ,Female ,Thematic analysis ,business ,Set (psychology) ,Qualitative research - Abstract
© 2019 Royal College of Obstetricians and Gynaecologists Objective: To quantify the effect of different methodological decisions on the identification of potential core outcomes to inform the development of recommendations for future core coutcome set developers. Design: Mixed methods study. Setting: A core outcome set for pre-eclampsia was used as an exemplar. Sample: A long list of potential core outcomes was developed by undertaking a systematic review of pre-eclampsia trials and performing a thematic analysis of in-depth patient interviews. Methods: Specific methods used to generate long lists of potential core outcomes were evaluated. Results: Different methodological decisions had a substantial impact on the identification of potential core outcomes. Extracting outcomes from published pre-eclampsia trials was an effective way of identifying 48 maternal, eight fetal, 25 neonatal outcomes, and eight patient-reported outcomes. Limiting the extraction of outcomes to primary outcomes or outcomes commonly reported in pre-eclampsia trials reduced the number and diversity of potential core outcomes identified. Thematic analysis of in-depth patient interviews ensured an additional five patient reported outcomes and six outcomes related to future child health were identified. Conclusions: Future core outcome set developers should use quantitative and qualitative methods when developing a long list of potential core outcomes. Tweetable abstract: @OfficialNIHR research published in @BJOGtweets informs new recommendations for future @coreoutcomes developers.
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- 2019
21. Effects of fruit and vegetable consumption on plasma antioxidant concentrations and blood pressure: a randomised controlled trial
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John, JH, Ziebland, S., Yudkin, P., Roe, LS, and Neil, Haw
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- 2002
22. Incurable, invisible and inconclusive: watchful waiting for chronic lymphocytic leukaemia and implications for doctor–patient communication
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EVANS, J., ZIEBLAND, S., and PETTITT, A. R.
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- 2012
- Full Text
- View/download PDF
23. Factors contributing to the time taken to consult with symptoms of lung cancer: a cross-sectional study
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Smith, S M, Campbell, N C, MacLeod, U, Lee, A J, Raja, A, Wyke, S, Ziebland, S B, Duff, E M, Ritchie, L D, and Nicolson, M C
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- 2009
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24. Patientsʼ perceptions of transrectal prostate biopsy: a qualitative study
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CHAPPLE, A. B., ZIEBLAND, S., BREWSTER, S., and MCPHERSON, A.
- Published
- 2007
25. A qualitative cross-country comparison of whether, when and how people diagnosed with lung cancer talk about cigarette smoking in narrative interviews
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Hajdarevic, S, Rasmussen, B, Overgaard Hasle, T, and Ziebland, S
- Abstract
Objectives To compare and examine whether, when and how patients with lung cancer in three countries, with different survival rates, talk about cigarette smoking and its relationship with help seeking. Design A qualitative cross-country comparison with analysis of narrative interviews. Setting Participants in Sweden, Denmark and England were interviewed during 2015-2016. Interviews, using a narrative approach, were conducted in participants’ home by trained and experienced qualitative researchers. Participants Seventy two men and women diagnosed with lung cancer were interviewed within six months of their diagnosis. Results The English participants, regardless of their own smoking status, typically raised the topic of smoking early in their interviews. Smoking was mentioned in relation to symptom appraisal and interactions with others, including health professionals. Participants in all three countries interpreted their symptoms in relation to their smoking status, but in Sweden (unlike England) there was no suggestion that this deterred them from seeking care. English participants, but not Swedish or Danish, recounted reluctance to consult healthcare professionals with their symptoms while they were still smoking, some gave up shortly before consulting. Some English patients described defensive strategies to challenge stigma or pre-empt other people’s assumptions about their culpability for the disease. A quarter of the Danish and 40% of the Swedish participants did not raise the topic of smoking at any point in their interview. Conclusion The causal relationship between smoking and lung cancer is well-known in all three countries, yet this comparative analysis suggests that the links between a sense of responsibility, stigma and reluctance to consult is not inevitable. These findings help illuminate why English patients with lung cancer tend to be diagnosed at a later stage than their Swedish counterparts.
- Published
- 2018
26. Parallel Session 31 – Miscellaneous: DIPEx (experiences of health and illness) an innovative multi media resource based on illness narratives
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McPherson, A. and Ziebland, S.
- Published
- 2003
27. Parallel Session 29 – Informed Patients and Use of Health Services: ‘Thereʼs no excuse these daysʼ how cancer patients use the internet
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Ziebland, S., Chapple, A., Evans, J., Dumelow, C., Prinjha, S., and Rozmovits, L.
- Published
- 2003
28. Stigma, Shame and Blame Experienced by Patients with Lung Cancer: Qualitative Study
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Chappele, A., Ziebland, S., and McPherson, A.
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Lung cancer -- Psychological aspects ,Lung cancer -- Educational aspects ,Lung cancer -- Care and treatment ,Patients -- Care and treatment ,Patients -- Psychological aspects ,Patients -- Educational aspects ,Cancer -- Care and treatment ,Cancer -- Psychological aspects ,Cancer -- Educational aspects - Published
- 2004
29. Is ‘watchful waiting’ a real choice for men with prostate cancer? A qualitative study
- Author
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Chapple, A., Ziebland, S., Herxheimer, A., Mcpherson, A., Shepperd, S., and Miller, R.
- Published
- 2002
30. Body image and weight change in middle age: a qualitative study
- Author
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ZIEBLAND, S, JAY, J, ROBERTSON, J, NEIL, A, and COWBURN, G
- Published
- 2000
31. Process evaluation of a research workshop and follow-up support to help practitioners from 13 weight management projects to carry out evaluations
- Author
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Rayner, M. and Ziebland, S.
- Published
- 1999
32. Patients’ initial steps to cancer diagnosis in Denmark, England and Sweden: what can a qualitative, cross-country comparison of narrative interviews tell us about potentially modifiable factors?
- Author
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MacArtney, J, Malmström, M, Overgaard Nielsen, T, Evans, J, Bernhardson, B, Hajdarevic, S, Chapple, A, Eriksson, L, Locock, L, Rasmussen, B, Vedsted, P, Tishelman, C, Andersen, R, and Ziebland, S
- Subjects
Adult ,Cross-Cultural Comparison ,Male ,Health Knowledge, Attitudes, Practice ,Lung Neoplasms ,Denmark ,Emotions ,Nursing ,Health Services Accessibility ,Secondary Care ,primary care ,General Practitioners ,Intestinal Neoplasms ,Humans ,Referral and Consultation ,Qualitative Research ,Aged ,Aged, 80 and over ,Sweden ,Narration ,international health services ,Primary Health Care ,Omvårdnad ,Research ,Uncertainty ,Middle Aged ,England ,Female ,Health Services Research ,RC - Abstract
Objectives To illuminate patterns observed in International Cancer Benchmarking Programme studies by extending understanding of the various influences on presentation and referral with cancer symptoms. Design Cross-country comparison of Denmark, England, and Sweden with qualitative analysis of in-depth interview accounts of the pre-diagnostic process in lung or bowel cancer. Participants 155 women and men, aged between 35 and 86 years old, diagnosed with lung or bowel cancer in the six months before interview. Setting Participants recruited through primary and secondary care, social media, and word-of-mouth. Interviews collected by social scientists or nurse researchers during 2015, mainly in participants’ homes. Results Participants reported difficulties in interpreting diffuse bodily sensations and symptoms and deciding when to consult. There were examples of swift referrals by primary care professionals in all three countries. In all countries participants described difficulty deciding if and when to consult, highlighting concerns about access to GP appointments and overstretched primary care services, although this appears less prominent in the Swedish data. It was not unusual for there to be more than one consultation before referral and we noted two distinct patterns of repeated consultation: (1) Situations where the participant left the primary care consultation with a plan of action about what should happen next. (2) Participants were unclear about under which conditions to return to the doctors. This second pattern sometimes extended over many weeks during which patients described uncertainty, and sometimes frustration, about if and when they should return and whether there were any other feasible investigations. The latter pattern appeared more evident in the interviews in England and Denmark than Sweden. Conclusion We suggest that if clear action plans, as part of safety netting, were routinely used in primary care consultations then uncertainty, false reassurance, and the inefficiency and distress of multiple consultations could be reduced.
- Published
- 2017
33. Outcome reporting across randomised controlled trials evaluating therapeutic interventions for pre-eclampsia: a systematic review
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Duffy, J, Hirsch, M, Kawsar, A, Gale, C, Pealing, L, Plana, MN, Showell, M, Williamson, PR, Khan, KS, Ziebland, S, and McManus, RJ
- Abstract
Background Standardising outcome collection and reporting in pre-eclampsia trials requires an appraisal of current outcome reporting. Objectives To map maternal and offspring outcome reporting across randomised trials evaluating therapeutic interventions for pre-eclampsia. Search strategy Randomised trials were identified by searching bibliographical databases from inception to January 2016. Selection criteria Randomised controlled trials. Data collection and analysis We systematically extracted and categorised outcomes reporting. Main results Seventy-nine randomised trials, reporting data from 31,615 maternal participants and 28,172 of their offspring, were included. Fifty-five different interventions were evaluated. Included trials reported 119 different outcomes, including 72 maternal outcomes and 47 offspring outcomes. Maternal outcomes were inconsistently reported across included trials, for example, 11 (14%) trials reported maternal mortality, reporting data from 12,422 participants (39%), and 16 (20%) trials reported cardiovascular morbidity, reporting data from 14,963 maternal participants (43%). Forty-three (54%) trials reported fetal outcomes and 23 (29%) trials reported neonatal outcomes. Twenty-eight trials (35%) reported offspring mortality. There was poor reporting of childhood outcomes: six trials (8%) reported neurodevelopmental outcomes. Less than half of included trials reported any relevant information regarding harms for maternal participants and their offspring. Conclusions Most randomised trials evaluating interventions for pre-eclampsia are missing information on clinically important outcomes and in particular have neglected to evaluate efficacy and safety in the offspring of participants. Developing and implementing a minimum core data set, known as a core outcome set, in future pre-eclampsia trials could help to address these issues.
- Published
- 2017
34. Developing a pre-eclampsia core outcome set. Round 1 results: 283 healthcare professionals, 41 researchers and 112 patients from 55 countries participated
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Duffy, JMN, Van't Hooft, J, Gale, C, Brown, M, Grobman, W, Fitzpatrick, R, Karumanchi, SA, Lucas, N, Magee, L, Mol, B, Stark, M, Thangaratinam, S, Wilson, M, Von Dadelszen, P, Williamson, P, Khan, K, Ziebland, S, McManus, RJ, and Medical Research Council
- Subjects
Science & Technology ,Obstetrics & Gynecology ,11 Medical And Health Sciences ,Obstetrics & Reproductive Medicine ,Life Sciences & Biomedicine - Published
- 2017
35. Depression at work, authenticity in question: Experiencing, concealing and revealing
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Ridge, D, Broom, A, Kokanović, R, Ziebland, S, Hill, N, Ridge, D, Broom, A, Kokanović, R, Ziebland, S, and Hill, N
- Abstract
Australia and the United Kingdom have introduced policies to protect employees who experience mental illness, including depression. However, a better understanding of the experiential issues workers face (e.g. sense of moral failure) is needed for the provision of appropriate and beneficial support. We analysed 73 interviews from the United Kingdom and Australia where narratives of depression and work intersected. Participants encountered difficulties in being (and performing as if) ‘authentic’ at work, with depression contributing to confusions about the self. The diffuse post-1960s imperative to ‘be yourself’ is experienced in conflicting ways: while some participants sought support from managers and colleagues (e.g. sick leave, back-to-work plans), many others put on a façade in an attempt to perform the ‘well’ and ‘authentic’ employee. We outline the contradictory forces at play for participants when authenticity and visibility are expected, yet, moral imperatives to be good (healthy) employees are normative.
- Published
- 2017
36. Effectiveness of health checks conducted by nurses in primary care: final results of the OXCHECK study. Imperial Cancer Research Fund OXCHECK Study Group
- Author
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Coulter, A, Fowler, G, Fuller, A, Jones, L, Lancaster, T, Lawrence, M, Mant, D, Muir, J, Neil, H, Oneil, C, Roe, L, Rusted, H, Schofield, T, Silagy, C, Thorogood, M, Yudkin, P, Ziebland, S, Freedman, D, Oggelsby, M, Joyce, S, Sweetman, Y, Smith, R, Bradley, P, Brown, R, and Choudhury, S
- Abstract
OBJECTIVE: To determine the effectiveness of health checks, performed by nurses in primary care, in reducing risk factors for cardiovascular disease and cancer. DESIGN: Randomised controlled trial. SETTING: Five urban general practices in Bedfordshire. SUBJECTS: 2205 men and women who were randomly allocated a first health check in 1989-90 and a re-examination in 1992-3 (the intervention group); 1916 men and women who were randomly allocated an initial health check in 1992-3 (the control group). All subjects were aged 35-64 at recruitment in 1989. MAIN OUTCOME MEASURES: Serum total cholesterol concentration, blood pressure, body mass index, and smoking prevalence (with biochemical validation of cessation); self reported dietary, exercise, and alcohol habits. RESULTS: Mean serum total cholesterol was 3.1% lower in the intervention group than controls (difference 0.19 mmol/l (95% confidence interval 0.12 to 0.26)); in women it was 4.5% lower (P < 0.0001) and in men 1.6% (P < 0.05), a significant difference between the sexes (P < 0.01). Self reported saturated fat intake was also significantly lower in the intervention group. Systolic and diastolic blood pressures and body mass index were respectively 1.9%, 1.9%, and 1.4% lower in the intervention group (P < 0.005 in all cases). There was a 3.9% (2.4 to 5.3) difference in the percentage of subjects with a cholesterol concentration > or = 8 mmol/l, but no significant differences in the number with diastolic blood pressure > or = 100 mm Hg or body mass index > or = 30 kg/m2. There was no significant difference between the two groups in prevalence of smoking or excessive alcohol use. Annual rechecks were no more effective than a single recheck at three years, but health checks led to a significant increase in visits to the nurse according to patients' degree of cardiovascular risk. CONCLUSIONS: The benefits of health checks were sustained over three years. The main effects were to promote dietary change and reduce cholesterol concentrations; small differences in blood pressure may have been attributable to accommodation to measurement. The benefits of systematic health promotion in primary care are real, but must be weighed against the costs in relation to other priorities.
- Published
- 2016
37. Lung cancer patients' perceptions of access to financial benefits: a qualitative study
- Author
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Chapple, A, Ziebland, S, McPherson, A, and Summerton, N
- Subjects
Adult ,Aged, 80 and over ,Male ,Lung Neoplasms ,Humans ,Female ,Middle Aged ,Original Papers ,Qualitative Research ,Social Security ,Stress, Psychological ,United Kingdom ,Aged - Abstract
BACKGROUND: Financial worries may add to the stress experienced by patients and their families, but they are often not discussed with health professionals. People with lung cancer usually have to give up work, and many are terminally ill. AIM: To explore the financial concerns, perceptions and experiences of claiming benefits of people with lung cancer. DESIGN OF STUDY: Qualitative study using narrative interviews. SETTING: United Kingdom. METHOD: Interviews with a maximum variation sample of 45 people with lung cancer, recruited through general practitioners, consultants, nurses and support groups. RESULTS: Some people did not know that they could claim financial benefits, others found claim forms complicated, or were unaware that they had no legal right for important allowances to be backdated. Some people had to 'struggle' to obtain much needed benefits to which they were entitled. Patients below retirement age said that they would prefer to be working, and many were shocked by how hard it was to obtain the information needed to make claims. There was some evidence that even those who are seriously ill, and life-time tax payers, feel stigma in claiming financial help. Nurses, doctors and other patients sometimes offered valuable guidance, but many patients did not receive timely advice. The special social security rules (and DS1500 report form), which might have allowed them to claim benefits more rapidly than usual and at a higher rate, were not always understood. CONCLUSION: Many reasons were found as to why people with lung cancer have difficulty getting the benefits that they are entitled to. Hospital and primary care staff who handle the issue sensitively and help set claims in motion provide a valuable service that should be replicated throughout the National Health Service.
- Published
- 2016
38. Experiences of infertility: where do men fit in?
- Author
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Hinton, L, Kurinczuk, JJ, and Ziebland, S
- Published
- 2016
39. Prescribing antibiotics to 'at-risk' children with influenza-like illness in primary care: qualitative study
- Author
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Ashdown, HF, Räisänen, U, Wang, K, Ziebland, S, and Harnden, A
- Abstract
Objectives NICE guidelines recommend immediate antibiotic treatment of respiratory tract infections in “at-risk” individuals with co-morbidities. Observational evidence suggests that influenza particularly predisposes children to bacterial complications. This study investigates GPs’ accounts of factors influencing their decision-making about antibiotic prescribing in management of at-risk children with influenza-like illness (ILI). Design Qualitative interview study using a maximum variation sample with thematic analysis through constant comparison Setting Semi-structured telephone interviews with UK GPs using a case vignette of a child with co-morbidities presenting with ILI Participants 41 GPs (41.5% male; 40 from England, 1 from Northern Ireland) with a range of characteristics including length of time in practice, paediatrics experience, practice setting, and deprivation. Results There was considerable uncertainty and variation in the way GPs responded to the case, and difference of opinion about how long-term co-morbidities should affect their antibiotic prescribing. Factors influencing their decision included the child’s case history and clinical examination; the GP’s view of the parent’s ability to self-manage; the GP’s own confidence and experiences of managing sick children; and assessment of individual vs. abstract risk. GPs rarely mentioned potential influenza infection or asked about immunisation status. All said they would want to see the child; views about delayed prescribing varied in relation to local health service provision including options for follow-up and paediatric services. Conclusions The study demonstrates diagnostic uncertainty and wide variation in GP decision-making about prescribing antibiotics to children with co-morbidity. Future guidelines might encourage consideration of a specific diagnosis such as influenza and risk assessment tools could be developed to allow clinicians to quantify the levels of risk associated with different types of co-morbidity. However, the wide range of clinical and non-clinical factors involved in decision-making during these consultations should also be considered in future guidelines.
- Published
- 2016
40. An alarming prognosis: How people affected by pancreatic cancer use (and avoid) Internet information
- Author
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Chapple, A, Evans, JV, Ziebland, S, McPherson, A, and McPherson, A
- Subjects
medicine.medical_specialty ,Health (social science) ,Public Administration ,media_common.quotation_subject ,education ,Internet and science and learning ,Filter (software) ,Pancreatic cancer ,medicine ,Quality (business) ,Internet research ,media_common ,business.industry ,Health Policy ,medicine.disease ,humanities ,Computer Science Applications ,Policy studies ,Harm ,Oncology ,Family medicine ,The Internet ,Worry ,Psychology ,business ,Social psychology ,Qualitative research - Abstract
This article looks at how patients with pancreatic cancer use the Internet, and considers its potential negative effects for people with a life threatening illness. We designed a qualitative study using semi-structured interviews collected by maximum variation sampling. Respondents were recruited from all over the UK in 2009/10. We interviewed 32 people with pancreatic cancer and eight relatives/carers of people who had recently died of pancreatic cancer. In contrast to a similar study we undertook in 2004, we found that the people interviewed in 2009/10 talked about using the Internet for health information as if it were a routine and unremarkable part of life. Patients gave few examples of harm from using the Internet, or of damage caused to their relationships with health professionals. We also found that patients and family carers were using a strategy to handle alarming information found online, with patients asking partners and family to filter what they found. In conclusion, concerns about serious negative effects of using the Internet for health information may be ill-founded, even when the Internet is used by patients with serious life threatening illness. Clinicians may worry that people will find unwanted or contradictory information, but it is probably counter-productive to try to steer people away from the web. Similarly, policy makers have focused on regulating the factual content of information on the web, but we found that it was the consequences of stumbling on factually correct, yet unwelcome, information that concerned the patients and their families in this study. Good practice guidelines and quality markers for health information may need to pay more attention to website design and user routing as well as factual content. © 2012 Policy Studies Organization.
- Published
- 2016
41. Is 'watchful waiting' a real choice for men with prostate cancer? A qualitative study
- Author
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Chapple, A, Ziebland, S, Herxheimer, A, McPherson, A, Shepperd, S, and Miller, R
- Abstract
OBJECTIVE: To understand what leads men to choose 'watchful waiting' rather than active treatment for cancer of the prostate. PATIENTS AND METHODS: Fifty men with confirmed prostate cancer in England, Wales and Scotland were interviewed about all aspects of their illness, for a Database of Individual Patients' Experience of illness. The sample included men at different stages of diagnosis and with experience of a wide range of treatments. We report here only what men said about their choice of treatment and the decision-making process. RESULTS: Watchful waiting would have been clinically inappropriate for almost half of the men (those with serious urinary symptoms and those with metastatic disease). However, few of the men who might have chosen watchful-waiting remembered this being presented as a serious option. Most in this group chose radical prostatectomy, radiotherapy, brachytherapy or cryosurgery. The few who chose watchful waiting had found doctors who supported their decision, had assessed the evidence from Internet sites, and were concerned about the side-effects and uncertain outcome of treatment. Men who chose watchful waiting, as well as those who opted for treatment, described considerable pressure from family members, doctors or support groups, to seek active treatment. CONCLUSION: This study helps to explain why some men will not contemplate watchful waiting, and why others may find it difficult to pursue that option. Understanding men's concerns may help clinicians to support men's treatment decisions. Treatment for prostate cancer is highly controversial because no randomized, controlled trials have shown whether or not active intervention increases survival. If trials are not completed it cannot be determined whether active treatments are the best course of action for men with prostate cancer.
- Published
- 2016
42. DIPEx (Database of Individual Patients' Experience of illness): A multimedia proposal to share experiences and information about illnesses between patients and health professionals
- Author
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Herxheimer, A, McPherson, A, Miller, R, Chapple, A, Shepperd, S, Ziebland, S, and Sanz, E
- Published
- 2016
43. QUALITATIVE METHODS IN HEALTH AND MEDICINE - BLOOR,M, TARABORRELLI,P
- Author
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ZIEBLAND, S
- Published
- 2016
44. Dietary effect on blood pressure - Reply
- Author
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Ziebland, S, Yudkin, P, John, J, and Neil, A
- Published
- 2016
45. SENSITIVITY TO CHANGE OVER TIME OF 4 HEALTH-STATUS INSTRUMENTS IN RHEUMATOID-ARTHRITIS
- Author
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MOWAT, A, FITZPATRICK, R, ZIEBLAND, S, and JENKINSON, C
- Published
- 2016
46. The DIPEx project: A systematic collection of personal illness experiences
- Author
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Herxheimer, A and Ziebland, S
- Abstract
We describe a large systematic collection of personal experiences of ilnesses and other health problems based on qualitative video- and audiointerviews with people in their homes. These are analysed and summarised on the website www.dipex.org, which is freely accessible to everyone. They are intended to help new patients and their families to understand the condition and what it may involve, and to help them in making important decisions together with their doctors and other professionals. The site is also valuable in teaching students and trainees in the health professions, by showing them how widely people differ in their experiences of illness and how they cope with problems. Students can learn directly how important it is to listen to patients in order to understand them and help them. © Hippocampus Verlag 2008.
- Published
- 2016
47. A database of patients' experiences (DIPEx): A multi-media approach to sharing experiences and information
- Author
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Herxheimer, A, McPherson, A, Miller, R, Chapple, A, Shepperd, S, and Ziebland, S
- Abstract
DIPEx (Database of Individual Patients' Experience of illness) is a new multimedia website (www.dipex.org) launched in July 2001. The plans were described in the Lancet last year. It links a database of patients' experiences of two serious conditions - essential hypertension and prostatic cancer - with evidence-based information about the illness and treatment options, and a range of other resources that may be useful, including support groups and hyperlinks to other websites. DIPEx aims to identify the questions and problems that matter to people when they are ill or have a health-related problem. It has great potential for informing patients and educating doctors, nurses and other health professionals, and it is a means of providing a patient-centred perspective to researchers, managers and those who commission health services. The DIPEx project combines a systematic collection and analysis of interviews with people about their experience of illness with evidence of the effects of treatments, and information about support groups and other resource materials. We believe that the DIPEx database is unique in the field of patient and healthcare communication. To ensure that it can operate independently of sectional interests it is now constituted as a charity governed by a board of trustees. The module for each condition included in the database begins with a videotaped summary of the interviews, with excerpts presented to illustrate the themes. Users can watch, listen to or read parts of the actual interviews. If they wish to move directly to particular topics, the keyword and hyperlink facilities will help them to navigate the site. The hyperlinks enable users to click on keywords to access other linked areas of the site, for example research evidence about the effectiveness of a specific treatment. The appeal and potency of illness narratives in written and electronic format has been amply demonstrated. However, even the many excellent descriptions of illness experience that exist are scattered and difficult to find when they are needed. The DIPEx project will draw together a single resource for all users, with relevant, evidence-based information and narratives reflecting the aspects of the illness that matter to those with the condition.
- Published
- 2016
48. Emergency contraception
- Author
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Ziebland, S and Garcia, P
- Published
- 2016
49. 'It's a mega dose of hormones, isn't it?' Why women may be reluctant to use emergency contraception
- Author
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Ziebland, S, Maxwell, K, and Greenhall, E
- Abstract
Objective. To study knowledge, altitudes, beliefs and sources of knowledge about emergency contraception in a sample of sexually active women, combining quantitative and qualitative methods. Design. Self administered questionnaire to women attending family planning clinics in London and Oxfordshire and interviews with those attending for emergency contraception. Subjects. Five hundred and ten women completed the questionnaire. Fifty three women who were seeking emergency contraception also took part in a semi-structured interview. Results. The respondents were well informed about the time limits and effectiveness of emergency contraception, yet 43 per cent believed it to be more risky to their health than regular use of combined oral contraception and 15 per cent were very concerned about the possible side effects. Conclusion. Many women are likely to remain resistant to using a treatment which is perceived as a strong dose of potentially toxic chemicals. The consensus of professional opinion on the safety of hormonal emergency contraception is not reflected among family planning clients. This needs to be taken into account by both health professionals advising individual patients and publicity campaigns promoting the uptake of emergency contraception.
- Published
- 2016
50. Understanding depression through a 'coming out' framework
- Author
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Ridge, D and Ziebland, S
- Abstract
Recently, Scambler and others have broadened the research agenda on stigma to include the wider meanings of stigma within society, and especially the role of identity politics e.g. gay liberation. Recognising that the categories 'homosexual' and 'depression' were socially constructed and stigmatised from the 19 th and 20 th centuries respectively, we draw on themes in conceptual models of coming out as gay or lesbian to sensitise our analysis to personal experiences of depression and the specific ways in which the condition is constructed. Thirty-eight narrative interviews with people in the UK in various stages of recovery from depression were analysed comparing themes to a 'coming out' framework. The applicability of coming out themes to understanding the construction of depression was evident. Themes included childhood difference; confusion; the depression closet; challenging stigma via the biology vs. nurture debate; re-casting depression as commonplace or even fashionable; contending with a shame-pride narrative; coming out and, finally, integrating the depression experience. By comparing 'coming out' themes with depression experience in detail for the first time, we illuminate how people understand depression, cope with and resist stigma, thus providing insights into the contemporary situation in Western societies for those facing depression. © 2011 Foundation for the Sociology of Health and Illness/Blackwell Publishing Ltd.
- Published
- 2016
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