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A study conducted at Chang Gung Memorial Hospital in Taiwan examined the effectiveness of negative pressure wound therapy (NPWT) in patients with deep sternal wound infections following cardiovascular surgery. The research, which included a systematic review and meta-analysis of 36 studies involving 3,681 patients, found that NPWT was associated with a significant reduction in mortality and reinfection rates compared to conventional wound management. The study concluded that NPWT is superior to conventional treatment for patients with deep sternal wound infections. [Extracted from the article]

The patent "Reduced pressure therapy apparatus construction and control" by Smith & Nephew Inc. focuses on methods and apparatuses for dressing and treating wounds with negative pressure therapy. This therapy aids in wound healing by reducing tissue oedema, encouraging blood flow, and promoting the formation of granulation tissue. The apparatus includes a housing with a negative pressure source, pressure sensor, and controller to operate the therapy, detect leaks, and provide indications. The patent outlines a method for operating the apparatus and includes claims for applying negative pressure wound therapy to multiple wounds simultaneously. [Extracted from the article]

Researchers at Hospital Universitario have found that the use of Negative Pressure Wound Therapy (NPWT) in pedicled flaps can improve graft integration and minimize complications in reconstructive microsurgery. The study involved nine patients with open wounds who required reconstructive surgery, with NPWT applied immediately after the procedure. The research concluded that NPWT can enhance vascularization, reduce edema, and prevent local complications such as hematoma and infection, leading to successful flap integration. For more information, readers can access the full article in the Journal of Reconstructive Microsurgery Open. [Extracted from the article]

Researchers from Northwestern University Feinberg School of Medicine conducted a systematic review on the use of Negative Pressure Wound Therapy with Instillation and Dwell (NPWTi-d) for periprosthetic infections after breast reconstruction. The study found that NPWTi-d was associated with high rates of breast pocket salvage and reduced time to implant reinsertion. Larger prospective and randomized trials are needed to further understand and optimize the effectiveness of NPWTi-d in this population. The findings were published in Plastic and Reconstructive Surgery - Global Open. [Extracted from the article]

A patent has been issued for a method and apparatus related to negative pressure wound therapy by inventors from the US and the UK, assigned to Smith & Nephew Inc. The patent focuses on devices and methods for controlling negative pressure therapy systems to aid in wound healing. The technology aims to reduce tissue swelling, promote blood flow, and accelerate wound closure, among other benefits. The patent details the components and functions of the apparatus, including pressure sensors, controllers, and indicators for monitoring and maintaining negative pressure levels in wound therapy. [Extracted from the article]

The article discusses a clinical trial, NCT06677099, focusing on the use of chest physiotherapy guided by electrical impedance tomography (EIT) in patients with difficult ventilator weaning. The trial aims to investigate the feasibility and efficacy of this approach in improving airway clearance and secretion retention in critically ill patients. The study is interventional, randomized, and involves two groups receiving different physiotherapy interventions. The trial is not yet recruiting participants, with an enrollment target of 80 patients and a completion date of December 30, 2025. [Extracted from the article]

Smith & Nephew PLC has been issued a patent for the protection of electronics in negative pressure wound therapy systems. The patent focuses on methods and apparatuses for dressing and treating wounds with reduced pressure therapy. The patent details the use of negative pressure therapy to aid in wound healing by reducing tissue edema, encouraging blood flow, and promoting rapid healing. The patent also includes claims for a medical treatment apparatus and system designed to provide therapy to users using electronic components and conductive tracks on printed circuit boards. [Extracted from the article]

A University of Malta researcher conducted a literature review on the effectiveness of prophylactic negative pressure wound therapy (iNPWT) in reducing surgical site infections (SSIs) post-laparotomy surgeries. The study found a positive association between iNPWT and a reduction in SSIs compared to standard dressings, although some studies reported no significant difference. The research aimed to inform nursing practitioners and physicians about the benefits of iNPWT in enhancing patient care and safety. More information on this study can be found in the SAGE Open Nursing journal. [Extracted from the article]

A study conducted at Yale University School of Medicine compared the effectiveness of negative pressure wound therapy (PICO dressing) versus standard dressing application after arterial vascular reconstructions. The research found that PICO dressing significantly reduced groin wound complications in patients undergoing open vascular reconstructions. The study highlights the value of adjunctive negative pressure therapy in reducing wound complications after arterial reconstructions in the inguinal region. The findings suggest that PICO dressing and certain types of procedures were associated with lower risks of groin complications. [Extracted from the article]

Researchers at Anhui Medical University in China conducted a study on the impact of Negative Pressure Wound Therapy (NPWT) on Diabetic Foot Ulcer (DFU) healing. The study found that NPWT upregulated the expression of RNA-binding proteins FUS and ILF2, which promoted wound healing by regulating keratinocyte function and reducing inflammation and oxidative stress. This research provides new insights into the mechanism by which NPWT aids in DFU healing. The study was peer-reviewed and published in the International Journal of Molecular Medicine. [Extracted from the article]

A patent application titled "Short Range Peer To Peer Network For Negative Pressure Wound Therapy Devices" was published online by inventors from various locations in the United States. The application describes a network system for hospitals using negative pressure wound therapy devices that can wirelessly communicate with each other. The devices include features such as user interfaces, controllers, and processing circuits to monitor therapy operations and device health. This innovation aims to enhance the monitoring and management of negative pressure wound therapy devices in healthcare settings. [Extracted from the article]

Researchers at Hainan Medical University conducted a study on the effects of Compound Xuejie Powder combined with negative pressure wound therapy (NPWT) on diabetic foot ulcers and blood flow in the dorsal foot artery. The study included 103 patients with diabetic foot ulcers and found that the treatment effectively inhibited local inflammation, improved blood flow, and promoted ulcer healing. The research was supported by the Hainan Provincial Natural Science Foundation and the Hainan Province Health Industry Research Project. The findings were published in the American Journal of Translational Research and have been peer-reviewed. [Extracted from the article]

A recent study conducted by the University of South Carolina has explored the use of silver collagen oxidized regenerated cellulose (ORC) dressings in conjunction with negative pressure wound therapy (NPWT) and reticulated open cell foam (ROCF) dressings. The study involved an expert panel consensus, which recommended the use of silver collagen ORC dressings with NPWT and ROCF dressings in various healthcare settings, including inpatient and outpatient care. However, the study also highlighted certain contraindications for the use of these dressings, such as in the presence of exposed unprotected organs or vessels, acutely ischemic wounds, and patient hypersensitivity to product components. Limited evidence exists on the use of NPWT in conjunction with silver collagen ORC dressings. [Extracted from the article]

A new report discusses research on hernias conducted at University Hospital Ostrava in the Czech Republic. The study aimed to determine if closed incision negative pressure wound therapy (ciNPWT) reduces the incidence of surgical site infections (SSIs) after ventral hernia repair with a polypropylene mesh. The study involved 100 patients divided into two groups, with one group receiving standard wound care and the other group receiving ciNPWT. The results showed that the ciNPWT group had a lower incidence of SSIs, although the difference was not statistically significant. Further studies with larger populations are needed to confirm these findings. [Extracted from the article]

A recent study conducted by researchers at the University of Missouri compared different types of incisional dressings and negative-pressure wound therapy (NPWT) for the prevention of infection and wound complications after primary total hip and knee arthroplasty (THA and TKA). The study analyzed 12 randomized controlled trials involving 1,939 patients who underwent THA or TKA with various dressing types. The results showed that alginate and hydrofiber dressings were associated with fewer postoperative changes compared to gauze. However, there was no statistically significant difference in the risk of wound complications or infections among all dressing types and NPWT compared to gauze. Further research is needed to determine if these dressings can reduce the risk of infection. [Extracted from the article]

A patent application has been submitted for a system and method to detect fluid contamination in a negative-pressure wound therapy (NPWT) system. The system includes a therapy unit with a first pump and a piezo-electric pump, as well as a controller with processing circuitry. The piezo-electric pump is used to detect fluid indication, and the controller can shut off the first pump and notify a caregiver if fluid is present. The system also includes a pressure sensor and can operate the first pump and piezo-electric pump simultaneously. This patent application provides a potential solution for monitoring and detecting fluid contamination in NPWT devices. [Extracted from the article]

A recent report from Indiana University School of Medicine discusses research on plastic and reconstructive surgery. The study focuses on implant-based breast reconstruction salvage using negative pressure wound therapy with instillation (NPWTi-d). The researchers compared outcomes of this salvage pathway with traditional implant removal. The study found that the salvage pathway was successful in 81.3% of cases, resulting in fewer implant-free days and a faster time to final reconstruction. This research provides valuable insights for patients and healthcare professionals in the field of plastic and reconstructive surgery. [Extracted from the article]

A recent study conducted by researchers from Qom University of Medical Sciences in Iran explored the use of negative pressure wound therapy (NPWT) in the treatment of necrotizing fasciitis following a total abdominal hysterectomy. The study focused on a 69-year-old female patient who experienced complications after surgery, including a change in the color of the incision site and a mild fever. Despite multiple debridement procedures, the wound did not improve significantly. However, after implementing NPWT, the patient's wound began to heal and decrease in size, with the administration of appropriate antibiotics. The researchers concluded that NPWT is a useful and safe method for promoting faster healing in wounds following a total abdominal hysterectomy. [Extracted from the article]

A recent study conducted at the Mayo Clinic in Rochester, Minnesota, explored the effectiveness of closed-incision negative pressure wound therapy (ciNPWT) in reducing postoperative complications in patients undergoing implant-based breast reconstruction after radiotherapy. The study found that ciNPWT demonstrated significant benefits, with no infections reported in the ciNPWT group compared to a 10.4% infection rate in the non-ciNPWT group. Wound complications were also significantly lower in the ciNPWT group. The researchers concluded that ciNPWT has the potential to reduce postoperative complications, improve patient outcomes, and offer cost-saving benefits in the long run. [Extracted from the article]

Researchers at Peking University International Hospital have conducted a study on the efficacy of cuff-shaving combined with negative pressure wound therapy (NPWT) in treating refractory exit-site infections (ESIs) and tunnel infections (TIs) in patients undergoing peritoneal dialysis (PD). The study compared surgical intervention with conservative management strategies and found that the combination of cuff-shaving and NPWT significantly improved the longevity of PD catheter function and demonstrated higher therapeutic efficacy. The researchers concluded that this integrated surgical strategy offers a promising solution for managing refractory ESIs and TIs in PD patients. The full study can be accessed in BMC Nephrology. [Extracted from the article]

A patent application by inventor Felix Clarence Quintanar describes a negative pressure wound therapy apparatus that can detect blockages and leaks in multiple wound dressings. The apparatus includes a negative pressure source, fluid flow paths, a pressure sensor, and a controller. The controller measures pressure, determines fluid retention capacities, detects blockages and leaks, and provides indications of these issues. The invention aims to improve the healing rate of wounds and can be used for various types of wounds. The patent application was filed on May 2, 2024, and made available online on August 29, 2024. [Extracted from the article]

Solventum Intellectual Properties Company has been issued a patent for a short-range peer-to-peer network for negative pressure wound therapy devices. The network system is designed for hospitals and includes multiple negative pressure wound therapy devices that form a mesh network. The devices have wireless radios, user interfaces, controllers, and processing circuits that allow for communication, monitoring of therapy operations, and display of connection strength. The system also enables the exchange of information between devices, such as operational status, energy levels, and therapy information. The patent provides detailed claims and descriptions of the network system. [Extracted from the article]

A recent study conducted by the University of Lleida in Barcelona, Spain, examined the use of incisional negative pressure wound therapy in pediatric patients undergoing surgery for non-idiopathic scoliosis. The study found that this therapy was effective in preventing surgical wound complications, such as infections and wound dehiscence, in children. The research also concluded that the use of this therapy was cost-effective, with a benefit of $12.93 for every $1.00 of extra costs. These findings provide valuable insights for healthcare professionals treating pediatric patients with scoliosis. [Extracted from the article]

A recent study conducted by the Royal College of Surgeons Ireland explores the use of negative-pressure wound therapy (NPWT) in reducing surgical site infections in patients undergoing midline laparotomy. The study aims to determine whether prophylactic NPWT can effectively reduce postoperative wound complications. The PROPEL-2 trial, which began in June 2023, is the largest independent multicenter randomized clinical trial on this topic and will compare standard treatment to two commercially available NPWT devices. The results of this study will provide valuable insights into the routine management of laparotomy wounds. [Extracted from the article]

A patent has been issued for apparatuses and methods for negative pressure wound therapy with switchable fluid management. The patent describes a device that provides negative pressure to a wound site using a cover layer, a porous hydrophobic layer, and a porous hydrophilic ring. The device aims to prevent fluid transmission when negative pressure is applied and allow fluid transmission when negative pressure is not being applied. The invention is intended to improve the healing rate of wounds and reduce the likelihood of infection. The patent was filed by inventors from the United Kingdom and assigned to T.J.Smith and Nephew Limited. [Extracted from the article]

A patent has been issued for negative pressure wound therapy apparatuses and methods. The patent, filed by inventors from various locations including the United States, United Kingdom, Italy, and Singapore, is assigned to Smith & Nephew Asia Pacific Pte. Limited. The patent describes apparatuses and methods for dressing and treating wounds using topical negative pressure therapy. This therapy is known to aid in the healing process of various types of wounds by reducing tissue edema, encouraging blood flow, and promoting the formation of granulation tissue. The apparatuses described in the patent include a negative pressure source, a connector port, switches, and a controller for adjusting operational parameters based on whether a canister or a wound dressing is connected to the connector port. [Extracted from the article]

Inventors Albert, Sean; Johnson, Timothy; Sears, Charles; Soto, Orlando; and Tortoriello, David have filed a patent application for a new type of negative pressure wound therapy (NPWT) bandage. The bandage is designed to be simple, inexpensive, and easy to use for wound care. It includes an integrated pump assembly that applies negative pressure to the wound, promoting healing by drawing out exudates. The bandage also features an automatic pressure indicator and limiter to prevent excessive negative pressure. The inventors hope that this new bandage design will address the limitations of current NPWT systems and provide an effective and affordable option for wound healing. [Extracted from the article]

A systematic review and meta-analysis conducted by researchers at Mashhad University of Medical Sciences in Iran examined the impact of negative pressure wound therapy (NPWT) on surgical site infection (SSI) rates in obese women undergoing cesarean sections. The study analyzed 20 included studies and found that NPWT reduced the rate of SSIs in obese women undergoing C-sections. The researchers concluded that NPWT is effective in reducing SSI rates and suggested that economic evaluations should be conducted to justify the costs of NPWT devices. The full article can be accessed for free through the provided link. [Extracted from the article]

Molnlycke Health Care AB has been issued a patent for a mobile negative pressure wound therapy (NPWT) device. The device is designed to promote healing of surgical, acute, and chronic wounds by applying negative pressure to the wound. The patent describes a start-up test sequence for the device, which helps reduce the risk of injury or discomfort for the user. The device includes an inlet, a canister for collecting liquid from the wound, a pump, a pressure sensor, and control circuitry. The device undergoes a start-up test sequence to ensure it meets predefined criteria before transitioning to therapy mode. [Extracted from the article]

A recent systematic review conducted by researchers at the University of Toronto explores the use of negative pressure wound therapy (NPWT) in temporizing traumatic leg wounds before surgery. The review analyzed 34 studies involving 804 patients who received NPWT. The findings suggest that NPWT can be effective in temporizing traumatic wounds while awaiting soft tissue reconstruction. The study provides valuable insights for healthcare professionals in the field of plastic and reconstructive surgery. [Extracted from the article]

A study conducted at Jikei University found that incisional negative pressure wound therapy (iNPWT) can reduce the incidence of surgical site infections and wound dehiscence in patients with lower intestinal perforation. The study compared a therapy group of 22 patients who received iNPWT with a control group of 65 patients. The therapy group had a lower incidence of surgical site infections (9.1% vs. 52.3%) and no cases of wound dehiscence. The researchers concluded that iNPWT can be effective in reducing surgical site infections in patients with lower intestinal perforation. [Extracted from the article]

This document provides information about an ongoing clinical trial in France that is studying the effectiveness of a single-use negative pressure wound therapy system called PICO in treating hard-to-heal venous leg ulcers (VLU). The trial aims to compare the effectiveness of PICO treatment to standard care treatment. The primary endpoint of the study is the healing of the wounds at 12 weeks or earlier. The trial will also assess secondary outcome measures such as quality of life and healthcare practitioner satisfaction. The trial is currently recruiting participants. [Extracted from the article]

A research study conducted at Van Training and Research Hospital in Turkey compared the effectiveness of two methods, negative-pressure wound therapy (NPWT) and gradual wound approximation (GWA), in treating infected fasciotomy wounds. The study included patients who had undergone fasciotomy surgery after sustaining crushing injuries in earthquakes. The results showed that both NPWT and GWA were effective in closing infected fasciotomy wounds, but GWA achieved closure in a shorter time and with fewer surgeries compared to NPWT. The study found no significant differences in skin graft requirements or complication rates between the two methods. [Extracted from the article]

A recent study conducted by researchers at the University of Tsukuba in Japan has found that negative pressure wound therapy (NPWT) can be effectively used for deep limb burns with poor normal skin periwound area. The researchers used a hydrocolloid wound dressing to seal the wounds and prevent leakage during NPWT. The study involved a 61-year-old woman who had suffered burns and required skin grafting. The researchers concluded that this method allows for easy and effective NPWT for deep limb burns with extensive burns. The research has been peer-reviewed and more information can be obtained from the University of Tsukuba. [Extracted from the article]

A new study conducted by the National University of Medical Sciences (NUMS) compared the efficacy of open versus closed negative-pressure wound therapy for contaminated and dirty surgical wounds. The study included 96 patients who underwent surgery and were divided into two groups: Group A received closed negative-pressure wound therapy, while Group B received open negative-pressure wound therapy. The results showed that closed negative-pressure wound therapy resulted in faster wound healing compared to open negative-pressure wound therapy, with similar complication rates. This research provides valuable insights for healthcare professionals and patients seeking effective wound healing methods. [Extracted from the article]