50 results on '"Vidavalur, Ramesh"'
Search Results
2. Advances to diminish global newborn kernicterus mortality
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Bhutani, Vinod K., Vidavalur, Ramesh, and Wong, Ronald J.
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- 2024
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3. Correction: Advances to diminish global newborn kernicterus mortality
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Bhutani, Vinod K., Vidavalur, Ramesh, and Wong, Ronald J.
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- 2024
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4. Prenatal choline supplementation improves biomarkers of maternal docosahexaenoic acid (DHA) status among pregnant participants consuming supplemental DHA: a randomized controlled trial
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Klatt, Kevin C, McDougall, Melissa Q, Malysheva, Olga V, Taesuwan, Siraphat, Loinard-González, Aura P, Nevins, Julie EH, Beckman, Kara, Bhawal, Ruchika, Anderson, Elizabeth, Zhang, Sheng, Bender, Erica, Jackson, Kristina H, King, D Janette, Dyer, Roger A, Devapatla, Srisatish, Vidavalur, Ramesh, Brenna, J Thomas, and Caudill, Marie A
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Nutrition ,Clinical Trials and Supportive Activities ,Perinatal Period - Conditions Originating in Perinatal Period ,Pediatric ,Complementary and Integrative Health ,Clinical Research ,Reproductive health and childbirth ,Good Health and Well Being ,Biomarkers ,Choline ,Dietary Supplements ,Docosahexaenoic Acids ,Female ,Humans ,Infant ,Newborn ,Phosphatidylcholines ,Pregnancy ,Vitamins ,prenatal choline supplementation ,pregnancy ,docosahexaenoic acid ,PEMT pathway ,omega-3 polyunsaturated fatty acids ,stable isotope ,Engineering ,Medical and Health Sciences ,Nutrition & Dietetics - Abstract
BackgroundDietary methyl donors (e.g., choline) support the activity of the phosphatidylethanolamine N-methyltransferase (PEMT) pathway, which generates phosphatidylcholine (PC) molecules enriched in DHA that are exported from the liver and made available to extrahepatic tissues.ObjectivesThis study investigated the effect of prenatal choline supplementation on biomarkers of DHA status among pregnant participants consuming supplemental DHA.MethodsPregnant participants (n = 30) were randomly assigned to receive supplemental choline intakes of 550 mg/d [500 mg/d d0-choline + 50 mg/d deuterium-labeled choline (d9-choline); intervention] or 25 mg/d (25 mg/d d9-choline; control) from gestational week (GW) 12-16 until delivery. All participants received a daily 200-mg DHA supplement and consumed self-selected diets. Fasting blood samples were obtained at baseline, GW 20-24, and GW 28-32; maternal/cord blood was obtained at delivery. Mixed-effects linear models were used to assess the impact of prenatal choline supplementation on maternal and newborn DHA status.ResultsCholine supplementation (550 vs. 25 mg/d) did not achieve a statistically significant intervention × time interaction for RBC PC-DHA (P = 0.11); a significant interaction was observed for plasma PC-DHA and RBC total DHA, with choline supplementation yielding higher levels (+32-38% and +8-11%, respectively) at GW 28-32 (P
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- 2022
5. Choline metabolome response to prenatal choline supplementation across pregnancy: A randomized controlled trial.
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Taesuwan, Siraphat, McDougall, Melissa, Malysheva, Olga, Bender, Erica, Nevins, Julie, Devapatla, Srisatish, Vidavalur, Ramesh, Caudill, Marie, and Klatt, Kevin
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PEMT pathway ,choline metabolome ,phosphatidylcholine ,pregnancy ,prenatal choline supplementation ,Adaptation ,Physiological ,Adult ,Case-Control Studies ,Choline ,Dietary Supplements ,Female ,Fetal Blood ,Fetus ,Humans ,Metabolome ,Placenta ,Pregnancy ,Young Adult - Abstract
Pregnancy places a unique stress upon choline metabolism, requiring adaptations to support both maternal and fetal requirements. The impact of pregnancy and prenatal choline supplementation on choline and its metabolome in free-living, healthy adults is relatively uncharacterized. This study investigated the effect of prenatal choline supplementation on maternal and fetal biomarkers of choline metabolism among free-living pregnant persons consuming self-selected diets. Participants were randomized to supplemental choline (as choline chloride) intakes of 550 mg/d (500 mg/d d0-choline + 50 mg/d methyl-d9-choline; intervention) or 25 mg/d d9-choline (control) from gestational week (GW) 12-16 until Delivery. Fasting blood and 24-h urine samples were obtained at study Visit 1 (GW 12-16), Visit 2 (GW 20-24), and Visit 3 (GW 28-32). At Delivery, maternal and cord blood and placental tissue samples were collected. Participants randomized to 550 (vs. 25) mg supplemental choline/d achieved higher (p
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- 2021
6. Efficacy and Costs of Three Pharmacotherapies for Patent Ductus Arteriosus Closure in Premature Infants
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Vidavalur, Ramesh
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- 2022
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7. Advances to diminish global newborn kernicterus mortality
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Bhutani, Vinod K., primary, Vidavalur, Ramesh, additional, and Wong, Ronald J., additional
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- 2023
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8. Advances to Diminish Global Newborn Kernicterus Mortality
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Wong, Ronald, primary and Vidavalur, Ramesh, additional
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- 2023
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9. Geo-Racial Epidemiological Estimates of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency Among Newborns in the United States.
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Vidavalur, Ramesh, additional and Bhutani, Vinod, additional
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- 2023
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10. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
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Hay, Simon I, Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbas, Kaja M, Abd-Allah, Foad, Abdulkader, Rizwan Suliankatchi, Abdulle, Abdishakur M, Abebo, Teshome Abuka, Abera, Semaw Ferede, Aboyans, Victor, Abu-Raddad, Laith J, Ackerman, Ilana N, Adedeji, Isaac A, Adetokunboh, Olatunji, Afshin, Ashkan, Aggarwal, Rakesh, Agrawal, Sutapa, Agrawal, Anurag, Ahmed, Muktar Beshir, Aichour, Miloud Taki Eddine, Aichour, Amani Nidhal, Aichour, Ibtihel, Aiyar, Sneha, Akinyemiju, Tomi F, Akseer, Nadia, Al Lami, Faris Hasan, Alahdab, Fares, Al-Aly, Ziyad, Alam, Khurshid, Alam, Noore, Alam, Tahiya, Alasfoor, Deena, Alene, Kefyalew Addis, Ali, Raghib, Alizadeh-Navaei, Reza, Alkaabi, Juma M, Alkerwi, Ala'a, Alla, François, Allebeck, Peter, Allen, Christine, Al-Maskari, Fatma, AlMazroa, Mohammad AbdulAziz, Al-Raddadi, Rajaa, Alsharif, Ubai, Alsowaidi, Shirina, Althouse, Benjamin M, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amini, Erfan, Ammar, Walid, Amoako, Yaw Ampem, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Anwari, Palwasha, Ärnlöv, Johan, Arora, Megha, Artaman, Al, Aryal, Krishna Kumar, Asgedom, Solomon W, Atey, Tesfay Mehari, Atnafu, Niguse Tadele, Avila-Burgos, Leticia, Avokpaho, Euripide Frinel G Arthur, Awasthi, Ashish, Awasthi, Shally, Azarpazhooh, Mahmoud Reza, Azzopardi, Peter, Babalola, Tesleem Kayode, Bacha, Umar, Badawi, Alaa, Balakrishnan, Kalpana, Bannick, Marlena S, Barac, Aleksandra, Barker-Collo, Suzanne L, Bärnighausen, Till, Barquera, Simon, Barrero, Lope H, Basu, Sanjay, Battista, Robert, Battle, Katherine E, Baune, Bernhard T, Bazargan-Hejazi, Shahrzad, Beardsley, Justin, Bedi, Neeraj, Béjot, Yannick, Bekele, Bayu Begashaw, Bell, Michelle L, Bennett, Derrick A, Bennett, James R, Bensenor, Isabela M, Benson, Jennifer, Berhane, Adugnaw, Berhe, Derbew Fikadu, Bernabé, Eduardo, Betsu, Balem Demtsu, Beuran, Mircea, Beyene, Addisu Shunu, Bhansali, Anil, Bhatt, Samir, Bhutta, Zulfiqar A, Biadgilign, Sibhatu, Bicer, Burcu Kucuk, Bienhoff, Kelly, Bikbov, Boris, Birungi, Charles, Biryukov, Stan, Bisanzio, Donal, Bizuayehu, Habtamu Mellie, Blyth, Fiona M, Boneya, Dube Jara, Bose, Dipan, Bou-Orm, Ibrahim R, Bourne, Rupert R A, Brainin, Michael, Brayne, Carol, Brazinova, Alexandra, Breitborde, Nicholas J K, Briant, Paul S, Britton, Gabrielle, Brugha, Traolach S, Buchbinder, Rachelle, Bulto, Lemma Negesa Bulto, Bumgarner, Blair R, Butt, Zahid A, Cahuana-Hurtado, Lucero, Cameron, Ewan, Campos-Nonato, Ismael Ricardo, Carabin, Hélène, Cárdenas, Rosario, Carpenter, David O, Carrero, Juan Jesus, Carter, Austin, Carvalho, Felix, Casey, Daniel, Castañeda-Orjuela, Carlos A, Castle, Chris D, Catalá-López, Ferrán, Chang, Jung-Chen, Charlson, Fiona J, Chaturvedi, Pankaj, Chen, Honglei, Chibalabala, Mirriam, Chibueze, Chioma Ezinne, Chisumpa, Vesper Hichilombwe, Chitheer, Abdulaal A, Chowdhury, Rajiv, Christopher, Devasahayam Jesudas, Ciobanu, Liliana G, Cirillo, Massimo, Colombara, Danny, Cooper, Leslie Trumbull, Cooper, Cyrus, Cortesi, Paolo Angelo, Cortinovis, Monica, Criqui, Michael H, Cromwell, Elizabeth A, Cross, Marita, Crump, John A, Dadi, Abel Fekadu, Dalal, Koustuv, Damasceno, Albertino, Dandona, Lalit, Dandona, Rakhi, das Neves, José, Davitoiu, Dragos V, Davletov, Kairat, de Courten, Barbora, De Leo, Diego, De Steur, Hans, Defo, Barthelemy Kuate, Degenhardt, Louisa, Deiparine, Selina, Dellavalle, Robert P, Deribe, Kebede, Deribew, Amare, Des Jarlais, Don C, Dey, Subhojit, Dharmaratne, Samath D, Dhillon, Preet K, Dicker, Daniel, Djalainia, Shirin, Do, Huyen Phuc, Dokova, Klara, Doku, David Teye, Dorsey, E Ray, dos Santos, Kadine Priscila Bender, Driscoll, Tim R, Dubey, Manisha, Duncan, Bruce Bartholow, Ebel, Beth E, Echko, Michelle, El-Khatib, Ziad Ziad, Enayati, Ahmadali, Endries, Aman Yesuf, Ermakov, Sergey Petrovich, Erskine, Holly E, Eshetie, Setegn, Eshrati, Babak, Esteghamati, Alireza, Estep, Kara, Fanuel, Fanuel Belayneh Bekele, Farag, Tamer, Farinha, Carla Sofia e Sa, Faro, André, Farzadfar, Farshad, Fazeli, Mir Sohail, Feigin, Valery L, Feigl, Andrea B, Fereshtehnejad, Seyed-Mohammad, Fernandes, João C, Ferrari, Alize J, Feyissa, Tesfaye Regassa, Filip, Irina, Fischer, Florian, Fitzmaurice, Christina, Flaxman, Abraham D, Foigt, Nataliya, Foreman, Kyle J, Franklin, Richard C, Frostad, Joseph J, Fullman, Nancy, Fürst, Thomas, Furtado, Joao M, Futran, Neal D, Gakidou, Emmanuela, Garcia-Basteiro, Alberto L, Gebre, Teshome, Gebregergs, Gebremedhin Berhe, Gebrehiwot, Tsegaye Tewelde, Geleijnse, Johanna M, Geleto, Ayele, Gemechu, Bikila Lencha, Gesesew, Hailay Abrha, Gething, Peter W, Ghajar, Alireza, Gibney, Katherine B, Gillum, Richard F, Ginawi, Ibrahim Abdelmageem Mohamed, Gishu, Melkamu Dedefo, Giussani, Giorgia, Godwin, William W, Goel, Kashish, Goenka, Shifalika, Goldberg, Ellen M, Gona, Philimon N, Goodridge, Amador, Gopalani, Sameer Vali, Gosselin, Richard A, Gotay, Carolyn C, Goto, Atsushi, Goulart, Alessandra Carvalho, Graetz, Nicholas, Gugnani, Harish Chander, Gupta, Prakash C, Gupta, Rajeev, Gupta, Tanush, Gupta, Vipin, Gupta, Rahul, Gutiérrez, Reyna A, Hachinski, Vladimir, Hafezi-Nejad, Nima, Hailu, Alemayehu Desalegne, Hailu, Gessessew Bugssa, Hamadeh, Randah Ribhi, Hamidi, Samer, Hammami, Mouhanad, Handal, Alexis J, Hankey, Graeme J, Hao, Yuantao, Harb, Hilda L, Hareri, Habtamu Abera, Haro, Josep Maria, Harun, Kimani M, Harvey, James, Hassanvand, Mohammad Sadegh, Havmoeller, Rasmus, Hay, Roderick J, Hedayati, Mohammad T, Hendrie, Delia, Henry, Nathaniel J, Heredia-Pi, Ileana Beatriz, Heydarpour, Pouria, Hoek, Hans W, Hoffman, Howard J, Horino, Masako, Horita, Nobuyuki, Hosgood, H Dean, Hostiuc, Sorin, Hotez, Peter J, Hoy, Damian G, Htet, Aung Soe, Hu, Guoqing, Huang, John J, Huynh, Chantal, Iburg, Kim Moesgaard, Igumbor, Ehimario Uche, Ikeda, Chad, Irvine, Caleb Mackay Salpeter, Islam, Sheikh Mohammed Shariful, Jacobsen, Kathryn H, Jahanmehr, Nader, Jakovljevic, Mihajlo B, James, Peter, Jassal, Simerjot K, Javanbakht, Mehdi, Jayaraman, Sudha P, Jeemon, Panniyammakal, Jensen, Paul N, Jha, Vivekanand, Jiang, Guohong, John, Denny, Johnson, Catherine O, Johnson, Sarah Charlotte, Jonas, Jost B, Jürisson, Mikk, Kabir, Zubair, Kadel, Rajendra, Kahsay, Amaha, Kamal, Ritul, Kar, Chittaranjan, Karam, Nadim E, Karch, André, Karema, Corine Kakizi, Karimi, Seyed M, Karimkhani, Chante, Kasaeian, Amir, Kassa, Getachew Mullu, Kassaw, Nigussie Assefa, Kassebaum, Nicholas J, Kastor, Anshul, Katikireddi, Srinivasa Vittal, Kaul, Anil, Kawakami, Norito, Keiyoro, Peter Njenga, Kemmer, Laura, Kengne, Andre Pascal, Keren, Andre, Kesavachandran, Chandrasekharan Nair, Khader, Yousef Saleh, Khalil, Ibrahim A, Khan, Ejaz Ahmad, Khang, Young-Ho, Khoja, Abdullah T, Khosravi, Ardeshir, Khubchandani, Jagdish, Kiadaliri, Aliasghar Ahmad, Kieling, Christian, Kim, Yun Jin, Kim, Daniel, Kimokoti, Ruth W, Kinfu, Yohannes, Kisa, Adnan, Kissimova-Skarbek, Katarzyna A, Kissoon, Niranjan, Kivimaki, Mika, Knudsen, Ann Kristin, Kokubo, Yoshihiro, Kolte, Dhaval, Kopec, Jacek A, Kosen, Soewarta, Kotsakis, Georgios A, Koul, Parvaiz A, Koyanagi, Ai, Kravchenko, Michael, Krohn, Kristopher J, Kumar, G Anil, Kumar, Pushpendra, Kyu, Hmwe H, Lager, Anton Carl Jonas, Lal, Dharmesh Kumar, Lalloo, Ratilal, Lallukka, Tea, Lambert, Nkurunziza, Lan, Qing, Lansingh, Van C, Larsson, Anders, Leasher, Janet L, Lee, Paul H, Leigh, James, Leshargie, Cheru Tesema, Leung, Janni, Leung, Ricky, Levi, Miriam, Li, Yichong, Li, Yongmei, Liang, Xiaofeng, Liben, Misgan Legesse, Lim, Stephen S, Linn, Shai, Liu, Patrick Y, Liu, Angela, Liu, Shiwei, Liu, Yang, Lodha, Rakesh, Logroscino, Giancarlo, Looker, Katharine J, Lopez, Alan D, Lorkowski, Stefan, Lotufo, Paulo A, Lozano, Rafael, Lucas, Timothy C D, Lunevicius, Raimundas, Lyons, Ronan A, Macarayan, Erlyn Rachelle King, Maddison, Emilie R, Magdy Abd El Razek, Hassan Magdy Abd, Magdy Abd El Razek, Mohammed, Magis-Rodriguez, Carlos, Mahdavi, Mahdi, Majdan, Marek, Majdzadeh, Reza, Majeed, Azeem, Malekzadeh, Reza, Malhotra, Rajesh, Malta, Deborah Carvalho, Mamun, Abdullah A, Manguerra, Helena, Manhertz, Treh, Mantovani, Lorenzo G, Mapoma, Chabila C, March, Lyn M, Marczak, Laurie B, Martinez-Raga, Jose, Martins, Paulo Henrique Viegas, Martins-Melo, Francisco Rogerlândio, Martopullo, Ira, März, Winfried, Mathur, Manu Raj, Mazidi, Mohsen, McAlinden, Colm, McGaughey, Madeline, McGrath, John J, McKee, Martin, Mehata, Suresh, Meier, Toni, Meles, Kidanu Gebremariam, Memiah, Peter, Memish, Ziad A, Mendoza, Walter, Mengesha, Melkamu Merid, Mengistie, Mubarek Abera, Mengistu, Desalegn Tadese, Mensah, George A, Meretoja, Tuomo J, Meretoja, Atte, Mezgebe, Haftay Berhane, Micha, Renata, Millear, Anoushka, Miller, Ted R, Minnig, Shawn, Mirarefin, Mojde, Mirrakhimov, Erkin M, Misganaw, Awoke, Mishra, Shiva Raj, Mitchell, Philip B, Mohammad, Karzan Abdulmuhsin, Mohammadi, Alireza, Mohammed, Muktar Sano Kedir, Mohammed, Kedir Endris, Mohammed, Shafiu, Mohan, Murali B V, Mokdad, Ali H, Mollenkopf, Sarah K, Monasta, Lorenzo, Montañez Hernandez, Julio Cesar, Montico, Marcella, Moradi-Lakeh, Maziar, Moraga, Paula, Morawska, Lidia, Mori, Rintaro, Morrison, Shane D, Moses, Mark, Mountjoy-Venning, Cliff, Mruts, Kalayu Birhane, Mueller, Ulrich O, Muller, Kate, Murdoch, Michele E, Murthy, Gudlavalleti Venkata Satyanarayana, Murthy, Srinivas, Musa, Kamarul Imran, Nachega, Jean B, Nagel, Gabriele, Naghavi, Mohsen, Naheed, Aliya, Naidoo, Kovin S, Nangia, Vinay, Nasher, Jamal T, Natarajan, Gopalakrishnan, Negasa, Dumessa Edessa, Negoi, Ruxandra Irina, Negoi, Ionut, Newton, Charles R, Ngunjiri, Josephine Wanjiku, Nguyen, Cuong Tat, Nguyen, Quyen Le, Nguyen, Trang Huyen, Nguyen, Grant, Nguyen, Minh, Nichols, Emma, Ningrum, Dina Nur Anggraini, Nong, Vuong Minh, Norheim, Ole F, Norrving, Bo, Noubiap, Jean Jacques N, Nyandwi, Alypio, Obermeyer, Carla Makhlouf, O'Donnell, Martin J, Ogbo, Felix Akpojene, Oh, In-Hwan, Okoro, Anselm, Oladimeji, Olanrewaju, Olagunju, Andrew Toyin, Olagunju, Tinuke Oluwasefunmi, Olsen, Helen E, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Ong, Kanyin, Opio, John Nelson, Oren, Eyal, Ortiz, Alberto, Osborne, Richard H, Osgood-Zimmerman, Aaron, Osman, Majdi, Ota, Erika, Owolabi, Mayowa O, PA, Mahesh, Pacella, Rosana E, Panda, Basant Kumar, Pandian, Jeyaraj Durai, Papachristou, Christina, Park, Eun-Kee, Parry, Charles D, Parsaeian, Mahboubeh, Patil, Snehal T, Patten, Scott B, Patton, George C, Paudel, Deepak, Paulson, Katherine, Pearce, Neil, Pereira, David M, Perez, Krystle Marie, Perico, Norberto, Pesudovs, Konrad, Peterson, Carrie Beth, Petri, William Arthur, Petzold, Max, Phillips, Michael Robert, Phipps, Geoffrey, Pigott, David M, Pillay, Julian David, Pinho, Christine, Piradov, Michael A, Plass, Dietrich, Pletcher, Martin A, Popova, Svetlana, Poulton, Richie G, Pourmalek, Farshad, Prabhakaran, Dorairaj, Prasad, Narayan, Purcell, Carrie, Purwar, Manorama, Qorbani, Mostafa, Quintanilla, Beatriz Paulina Ayala, Rabiee, Rynaz H S, Radfar, Amir, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Afarin, Rahimi-Movaghar, Vafa, Rahman, Mohammad Hifz Ur, Rahman, Muhammad Aziz, Rahman, Mahfuzar, Rai, Rajesh Kumar, Rajsic, Sasa, Ram, Usha, Ranabhat, Chhabi Lal, Rangaswamy, Thara, Rankin, Zane, Rao, Paturi Vishnupriya, Rao, Puja C, Rawaf, Salman, Ray, Sarah E, Reiner, Robert C, Reinig, Nikolas, Reitsma, Marissa, Remuzzi, Giuseppe, Renzaho, Andre M N, Resnikoff, Serge, Rezaei, Satar, Ribeiro, Antonio L, Rivas, Jacqueline Castillo, Roba, Hirbo Shore, Robinson, Stephen R, Rojas-Rueda, David, Rokni, Mohammad Bagher, Ronfani, Luca, Roshandel, Gholamreza, Roth, Gregory A, Rothenbacher, Dietrich, Roy, Ambuj, Rubagotti, Enrico, Ruhago, George Mugambage, Saadat, Soheil, Safdarian, Mahdi, Safiri, Saeid, Sagar, Rajesh, Sahathevan, Ramesh, Sahraian, Mohammad Ali, Salama, Joseph, Saleh, Muhammad Muhammad, Salomon, Joshua A, Salvi, Sundeep Santosh, Samy, Abdallah M, Sanabria, Juan Ramon, Sanchez-Niño, Maria Dolores, Santomauro, Damian, Santos, João Vasco, Santos, Itamar S, Santric Milicevic, Milena M, Sartorius, Benn, Satpathy, Maheswar, Sawhney, Monika, Saxena, Sonia, Schelonka, Kathryn, Schmidt, Maria Inês, Schneider, Ione J C, Schöttker, Ben, Schutte, Aletta E, Schwebel, David C, Schwendicke, Falk, Seedat, Soraya, Sepanlou, Sadaf G, Servan-Mori, Edson E, Shaheen, Amira, Shaikh, Masood Ali, Shamsipour, Mansour, Sharma, Rajesh, Sharma, Jayendra, She, Jun, Shi, Peilin, Shibuya, Kenji, Shields, Chloe, Shifa, Girma Temam, Shiferaw, Mekonnen Sisay, Shigematsu, Mika, Shiri, Rahman, Shirkoohi, Reza, Shirude, Shreya, Shishani, Kawkab, Shoman, Haitham, Siabani, Soraya, Sibai, Abla Mehio, Sigfusdottir, Inga Dora, Silberberg, Donald H, Silva, Diego Augusto Santos, Silva, João Pedro, Silveira, Dayane Gabriele Alves, Singh, Jasvinder A, Singh, Om Prakash, Singh, Narinder Pal, Singh, Virendra, Sinha, Dhirendra Narain, Skiadaresi, Eirini, Slepak, Erica Leigh, Smith, David L, Smith, Mari, Sobaih, Badr H A, Sobngwi, Eugene, Soljak, Michael, Sorensen, Reed J D, Sousa, Tatiane Cristina Moraes, Sposato, Luciano A, Sreeramareddy, Chandrashekhar T, Srinivasan, Vinay, Stanaway, Jeffrey D, Stathopoulou, Vasiliki, Steel, Nicholas, Stein, Dan J, Steiner, Caitlyn, Steinke, Sabine, Stokes, Mark Andrew, Stovner, Lars Jacob, Strub, Bryan, Subart, Michelle, Sufiyan, Muawiyyah Babale, Sunguya, Bruno F, Sur, Patrick J, Swaminathan, Soumya, Sykes, Bryan L, Sylte, Dillon, Szoeke, Cassandra E I, Tabarés-Seisdedos, Rafael, Tadakamadla, Santosh Kumar, Taffere, Getachew Redae, Takala, Jukka S, Tandon, Nikhil, Tanne, David, Tarekegn, Yihunie L, Tavakkoli, Mohammad, Taveira, Nuno, Taylor, Hugh R, Tegegne, Teketo Kassaw, Tehrani-Banihashemi, Arash, Tekelab, Tesfalidet, Terkawi, Abdullah Sulieman, Tesfaye, Dawit Jember, Tesssema, Belay, Thakur, JS, Thamsuwan, Ornwipa, Theadom, Alice M, Theis, Andrew M, Thomas, Katie E, Thomas, Nihal, Thompson, Robert, Thrift, Amanda G, Tobe-Gai, Ruoyan, Tobollik, Myriam, Tonelli, Marcello, Topor-Madry, Roman, Tortajada, Miguel, Touvier, Mathilde, Traebert, Jefferson, Tran, Bach Xuan, Troeger, Christopher, Truelsen, Thomas, Tsoi, Derrick, Tuzcu, Emin Murat, Tymeson, Hayley, Tyrovolas, Stefanos, Ukwaja, Kingsley Nnanna, Undurraga, Eduardo A, Uneke, Chigozie Jesse, Updike, Rachel, Uthman, Olalekan A, Uzochukwu, Benjamin S Chudi, van Boven, Job F M, Varughese, Santosh, Vasankari, Tommi, Veerman, Lennert J, Venkatesh, S, Venketasubramanian, Narayanaswamy, Vidavalur, Ramesh, Vijayakumar, Lakshmi, Violante, Francesco S, Vishnu, Abhishek, Vladimirov, Sergey K, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Vos, Theo, Wadilo, Fiseha, Wakayo, Tolassa, Wallin, Mitchell T, Wang, Yuan-Pang, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Weiss, Daniel J, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A, Wijeratne, Tissa, Williams, Hywel C, Wiysonge, Charles Shey, Woldeyes, Belete Getahun, Wolfe, Charles D A, Woodbrook, Rachel, Woolf, Anthony D, Workicho, Abdulhalik, Xavier, Denis, Xu, Gelin, Yadgir, Simon, Yaghoubi, Mohsen, Yakob, Bereket, Yan, Lijing L, Yano, Yuichiro, Ye, Pengpeng, Yihdego, Mahari Gidey, Yimam, Hassen Hamid, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Yotebieng, Marcel, Younis, Mustafa Z, Yu, Chuanhua, Zaidi, Zoubida, Zaki, Maysaa El Sayed, Zegeye, Elias Asfaw, Zenebe, Zerihun Menlkalew, Zhang, Xueying, Zheng, Yingfeng, Zhou, Maigeng, Zipkin, Ben, Zodpey, Sanjay, Zoeckler, Leo, Zuhlke, Liesl Joanna, and Murray, Christopher J L
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- 2017
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11. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016: a systematic analysis for the Global Burden of Disease Study 2016
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Wang, Haidong, Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbas, Kaja M, Abd-Allah, Foad, Abera, Semaw Ferede, Abraha, Haftom Niguse, Abu-Raddad, Laith J, Abu-Rmeileh, Niveen M E, Adedeji, Isaac Akinkunmi, Adedoyin, Rufus Adesoji, Adetifa, Ifedayo Morayo O, Adetokunboh, Olatunji, Afshin, Ashkan, Aggarwal, Rakesh, Agrawal, Anurag, Agrawal, Sutapa, Ahmad Kiadaliri, Aliasghar, Ahmed, Muktar Beshir, Aichour, Miloud Taki Eddine, Aichour, Amani Nidhal, Aichour, Ibthiel, Aiyar, Sneha, Akanda, Ali Shafqat, Akinyemiju, Tomi F, Akseer, Nadia, Al Lami, Faris Hasan, Alabed, Samer, Alahdab, Fares, Al-Aly, Ziyad, Alam, Khurshid, Alam, Noore, Alasfoor, Deena, Aldridge, Robert William, Alene, Kefyalew Addis, Al-Eyadhy, Ayman, Alhabib, Samia, Ali, Raghib, Alizadeh-Navaei, Reza, Aljunid, Syed M, Alkaabi, Juma M, Alkerwi, Ala'a, Alla, François, Allam, Shalini D, Allebeck, Peter, Al-Raddadi, Rajaa, Alsharif, Ubai, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Amare, Azmeraw T, Ameh, Emmanuel A, Amini, Erfan, Ammar, Walid, Amoako, Yaw Ampem, Anber, Nahla, Andrei, Catalina Liliana, Androudi, Sofia, Ansari, Hossein, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Anwari, Palwasha, Ärnlöv, Johan, Arora, Megha, Artaman, Al, Aryal, Krishna Kumar, Asayesh, Hamid, Asgedom, Solomon Weldegebreal, Asghar, Rana Jawad, Assadi, Reza, Assaye, Ashagre Molla, Atey, Tesfay Mehari, Atre, Sachin R, Avila-Burgos, Leticia, Avokpaho, Euripide Frinel G Arthur, Awasthi, Ashish, Babalola, Tesleem Kayode, Bacha, Umar, Badawi, Alaa, Balakrishnan, Kalpana, Balalla, Shivanthi, Barac, Aleksandra, Barber, Ryan M, Barboza, Miguel A, Barker-Collo, Suzanne L, Bärnighausen, Till, Barquera, Simon, Barregard, Lars, Barrero, Lope H, Baune, Bernhard T, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Beghi, Ettore, Béjot, Yannick, Bekele, Bayu Begashaw, Bell, Michelle L, Bello, Aminu K, Bennett, Derrick A, Bennett, James R, Bensenor, Isabela M, Benson, Jennifer, Berhane, Adugnaw, Berhe, Derbew Fikadu, Bernabé, Eduardo, Beuran, Mircea, Beyene, Addisu Shunu, Bhala, Neeraj, Bhansali, Anil, Bhaumik, Soumyadeep, Bhutta, Zulfiqar A, Bicer, Burcu Kucuk, Bidgoli, Hassan Haghparast, Bikbov, Boris, Birungi, Charles, Biryukov, Stan, Bisanzio, Donal, Bizuayehu, Habtamu Mellie, Bjerregaard, Peter, Blosser, Christopher D, Boneya, Dube Jara, Boufous, Soufiane, Bourne, Rupert R A, Brazinova, Alexandra, Breitborde, Nicholas J K, Brenner, Hermann, Brugha, Traolach S, Bukhman, Gene, Bulto, Lemma Negesa Bulto, Bumgarner, Blair Randal, Burch, Michael, Butt, Zahid A, Cahill, Leah E, Cahuana-Hurtado, Lucero, Campos-Nonato, Ismael Ricardo, Car, Josip, Car, Mate, Cárdenas, Rosario, Carpenter, David O, Carrero, Juan Jesus, Carter, Austin, Castañeda-Orjuela, Carlos A, Castro, Franz F, Castro, Ruben Estanislao, Catalá-López, Ferrán, Chen, Honglei, Chiang, Peggy Pei-Chia, Chibalabala, Mirriam, Chisumpa, Vesper Hichilombwe, Chitheer, Abdulaal A, Choi, Jee-Young Jasmine, Christensen, Hanne, Christopher, Devasahayam Jesudas, Ciobanu, Liliana G, Cirillo, Massimo, Cohen, Aaron J, Colquhoun, Samantha M, Coresh, Josef, Criqui, Michael H, Cromwell, Elizabeth A, Crump, John A, Dandona, Lalit, Dandona, Rakhi, Dargan, Paul I, das Neves, José, Davey, Gail, Davitoiu, Dragos V, Davletov, Kairat, de Courten, Barbora, De Leo, Diego, Degenhardt, Louisa, Deiparine, Selina, Dellavalle, Robert P, Deribe, Kebede, Deribew, Amare, Des Jarlais, Don C, Dey, Subhojit, Dharmaratne, Samath D, Dherani, Mukesh K, Diaz-Torné, Cesar, Ding, Eric L, Dixit, Priyanka, Djalalinia, Shirin, Do, Huyen Phuc, Doku, David Teye, Donnelly, Christl Ann, dos Santos, Kadine Priscila Bender, Douwes-Schultz, Dirk, Driscoll, Tim R, Duan, Leilei, Dubey, Manisha, Duncan, Bruce Bartholow, Dwivedi, Laxmi Kant, Ebrahimi, Hedyeh, El Bcheraoui, Charbel, Ellingsen, Christian Lycke, Enayati, Ahmadali, Endries, Aman Yesuf, Ermakov, Sergey Petrovich, Eshetie, Setegn, Eshrati, Babak, Eskandarieh, Sharareh, Esteghamati, Alireza, Estep, Kara, Fanuel, Fanuel Belayneh Bekele, Faro, André, Farvid, Maryam S, Farzadfar, Farshad, Feigin, Valery L, Fereshtehnejad, Seyed-Mohammad, Fernandes, Jefferson G, Fernandes, João C, Feyissa, Tesfaye Regassa, Filip, Irina, Fischer, Florian, Foigt, Nataliya, Foreman, Kyle J, Frank, Tahvi, Franklin, Richard C, Fraser, Maya, Friedman, Joseph, Frostad, Joseph J, Fullman, Nancy, Fürst, Thomas, Furtado, Joao M, Futran, Neal D, Gakidou, Emmanuela, Gambashidze, Ketevan, Gamkrelidze, Amiran, Gankpé, Fortuné Gbètoho, Garcia-Basteiro, Alberto L, Gebregergs, Gebremedhin Berhe, Gebrehiwot, Tsegaye Tewelde, Gebrekidan, Kahsu Gebrekirstos, Gebremichael, Mengistu Welday, Gelaye, Amha Admasie, Geleijnse, Johanna M, Gemechu, Bikila Lencha, Gemechu, Kasiye Shiferaw, Genova-Maleras, Ricard, Gesesew, Hailay Abrha, Gething, Peter W, Gibney, Katherine B, Gill, Paramjit Singh, Gillum, Richard F, Giref, Ababi Zergaw, Girma, Bedilu Weji, Giussani, Giorgia, Goenka, Shifalika, Gomez, Beatriz, Gona, Philimon N, Gopalani, Sameer Vali, Goulart, Alessandra Carvalho, Graetz, Nicholas, Gugnani, Harish Chander, Gupta, Prakash C, Gupta, Rahul, Gupta, Rajeev, Gupta, Tanush, Gupta, Vipin, Haagsma, Juanita A, Hafezi-Nejad, Nima, Hakuzimana, Alex, Halasa, Yara A, Hamadeh, Randah Ribhi, Hambisa, Mitiku Teshome, Hamidi, Samer, Hammami, Mouhanad, Hancock, Jamie, Handal, Alexis J, Hankey, Graeme J, Hao, Yuantao, Harb, Hilda L, Hareri, Habtamu Abera, Harikrishnan, Sivadasanpillai, Haro, Josep Maria, Hassanvand, Mohammad Sadegh, Havmoeller, Rasmus, Hay, Roderick J, Hay, Simon I, He, Fei, Heredia-Pi, Ileana Beatriz, Herteliu, Claudiu, Hilawe, Esayas Haregot, Hoek, Hans W, Horita, Nobuyuki, Hosgood, H Dean, Hostiuc, Sorin, Hotez, Peter J, Hoy, Damian G, Hsairi, Mohamed, Htet, Aung Soe, Hu, Guoqing, Huang, John J, Huang, Hsiang, Iburg, Kim Moesgaard, Igumbor, Ehimario Uche, Ileanu, Bogdan Vasile, Inoue, Manami, Irenso, Asnake Ararsa, Irvine, Caleb M S, Islam, Sheikh Mohammed Shariful, Islam, Nazrul, Jacobsen, Kathryn H, Jaenisch, Thomas, Jahanmehr, Nader, Jakovljevic, Mihajlo B, Javanbakht, Mehdi, Jayatilleke, Achala Upendra, Jeemon, Panniyammakal, Jensen, Paul N, Jha, Vivekanand, Jin, Ye, John, Denny, John, Oommen, Johnson, Sarah Charlotte, Jonas, Jost B, Jürisson, Mikk, Kabir, Zubair, Kadel, Rajendra, Kahsay, Amaha, Kalkonde, Yogeshwar, Kamal, Ritul, Kan, Haidong, Karch, André, Karema, Corine Kakizi, Karimi, Seyed M, Karthikeyan, Ganesan, Kasaeian, Amir, Kassaw, Nigussie Assefa, Kassebaum, Nicholas J, Kastor, Anshul, Katikireddi, Srinivasa Vittal, Kaul, Anil, Kawakami, Norito, Kazanjan, Konstantin, Keiyoro, Peter Njenga, Kelbore, Sefonias Getachew, Kemp, Andrew Haddon, Kengne, Andre Pascal, Keren, Andre, Kereselidze, Maia, Kesavachandran, Chandrasekharan Nair, Ketema, Ezra Belay, Khader, Yousef Saleh, Khalil, Ibrahim A, Khan, Ejaz Ahmad, Khan, Gulfaraz, Khang, Young-Ho, Khera, Sahil, Khoja, Abdullah Tawfih Abdullah, Khosravi, Mohammad Hossein, Kibret, Getiye Dejenu, Kieling, Christian, Kim, Yun Jin, Kim, Cho-il, Kim, Daniel, Kim, Pauline, Kim, Sungroul, Kimokoti, Ruth W, Kinfu, Yohannes, Kishawi, Sami, Kissoon, Niranjan, Kivimaki, Mika, Knudsen, Ann Kristin, Kokubo, Yoshihiro, Kopec, Jacek A, Kosen, Soewarta, Koul, Parvaiz A, Koyanagi, Ai, Kravchenko, Michael, Krohn, Kristopher J, Kuate Defo, Barthelemy, Kuipers, Ernst J, Kulikoff, Xie Rachel, Kulkarni, Veena S, Kumar, G Anil, Kumar, Pushpendra, Kumsa, Fekede Asefa, Kutz, Michael, Lachat, Carl, Lagat, Abraham K, Lager, Anton Carl Jonas, Lal, Dharmesh Kumar, Lalloo, Ratilal, Lambert, Nkurunziza, Lan, Qing, Lansingh, Van C, Larson, Heidi J, Larsson, Anders, Laryea, Dennis Odai, Lavados, Pablo M, Laxmaiah, Avula, Lee, Paul H, Leigh, James, Leung, Janni, Leung, Ricky, Levi, Miriam, Li, Yongmei, Liao, Yu, Liben, Misgan Legesse, Lim, Stephen S, Linn, Shai, Lipshultz, Steven E, Liu, Shiwei, Lodha, Rakesh, Logroscino, Giancarlo, Lorch, Scott A, Lorkowski, Stefan, Lotufo, Paulo A, Lozano, Rafael, Lunevicius, Raimundas, Lyons, Ronan A, Ma, Stefan, Macarayan, Erlyn RachelleKing, Machado, Isis Eloah, Mackay, Mark T, Magdy Abd El Razek, Mohammed, Magis-Rodriguez, Carlos, Mahdavi, Mahdi, Majdan, Marek, Majdzadeh, Reza, Majeed, Azeem, Malekzadeh, Reza, Malhotra, Rajesh, Malta, Deborah Carvalho, Mantovani, Lorenzo G, Manyazewal, Tsegahun, Mapoma, Chabila C, Marczak, Laurie B, Marks, Guy B, Martin, Elena Alvarez, Martinez-Raga, Jose, Martins-Melo, Francisco Rogerlândio, Massano, João, Maulik, Pallab K, Mayosi, Bongani M, Mazidi, Mohsen, McAlinden, Colm, McGarvey, Stephen Theodore, McGrath, John J, McKee, Martin, Mehata, Suresh, Mehndiratta, Man Mohan, Mehta, Kala M, Meier, Toni, Mekonnen, Tefera Chane, Meles, Kidanu Gebremariam, Memiah, Peter, Memish, Ziad A, Mendoza, Walter, Mengesha, Melkamu Merid, Mengistie, Mubarek Abera, Mengistu, Desalegn Tadese, Menon, Geetha R, Menota, Bereket Gebremichael, Mensah, George A, Meretoja, Tuomo J, Meretoja, Atte, Mezgebe, Haftay Berhane, Micha, Renata, Mikesell, Joseph, Miller, Ted R, Mills, Edward J, Minnig, Shawn, Mirarefin, Mojde, Mirrakhimov, Erkin M, Misganaw, Awoke, Mishra, Shiva Raj, Mohammad, Karzan Abdulmuhsin, Mohammadi, Alireza, Mohammed, Kedir Endris, Mohammed, Shafiu, Mohan, Murali B V, Mohanty, Sanjay K, Mokdad, Ali H, Mollenkopf, Sarah K, Molokhia, Mariam, Monasta, Lorenzo, Montañez Hernandez, Julio Cesar, Montico, Marcella, Mooney, Meghan D, Moore, Ami R, Moradi-Lakeh, Maziar, Moraga, Paula, Morawska, Lidia, Mori, Rintaro, Morrison, Shane D, Mruts, Kalayu Birhane, Mueller, Ulrich O, Mullany, Erin, Muller, Kate, Murthy, Gudlavalleti Venkata Satyanarayana, Murthy, Srinivas, Musa, Kamarul Imran, Nachega, Jean B, Nagata, Chie, Nagel, Gabriele, Naghavi, Mohsen, Naidoo, Kovin S, Nanda, Lipika, Nangia, Vinay, Nascimento, Bruno Ramos, Natarajan, Gopalakrishnan, Negoi, Ionut, Nguyen, Cuong Tat, Nguyen, Quyen Le, Nguyen, Trang Huyen, Nguyen, Grant, Ningrum, Dina Nur Anggraini, Nisar, Muhammad Imran, Nomura, Marika, Nong, Vuong Minh, Norheim, Ole F, Norrving, Bo, Noubiap, Jean Jacques N, Nyakarahuka, Luke, O'Donnell, Martin J, Obermeyer, Carla Makhlouf, Ogbo, Felix Akpojene, Oh, In-Hwan, Okoro, Anselm, Oladimeji, Olanrewaju, Olagunju, Andrew Toyin, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Oren, Eyal, Ortiz, Alberto, Osgood-Zimmerman, Aaron, Ota, Erika, Owolabi, Mayowa O, Oyekale, Abayomi Samuel, PA, Mahesh, Pacella, Rosana E, Pakhale, Smita, Pana, Adrian, Panda, Basant Kumar, Panda-Jonas, Songhomitra, Park, Eun-Kee, Parsaeian, Mahboubeh, Patel, Tejas, Patten, Scott B, Patton, George C, Paudel, Deepak, Pereira, David M, Perez-Padilla, Rogelio, Perez-Ruiz, Fernando, Perico, Norberto, Pervaiz, Aslam, Pesudovs, Konrad, Peterson, Carrie Beth, Petri, William Arthur, Petzold, Max, Phillips, Michael Robert, Piel, Frédéric B, Pigott, David M, Pishgar, Farhad, Plass, Dietrich, Polinder, Suzanne, Popova, Svetlana, Postma, Maarten J, Poulton, Richie G, Pourmalek, Farshad, Prasad, Narayan, Purwar, Manorama, Qorbani, Mostafa, Quintanilla, Beatriz Paulina Ayala, Rabiee, Rynaz H S, Radfar, Amir, Rafay, Anwar, Rahimi-Movaghar, Afarin, Rahimi-Movaghar, Vafa, Rahman, Mohammad Hifz Ur, Rahman, Sajjad Ur, Rahman, Mahfuzar, Rai, Rajesh Kumar, Rajsic, Sasa, Ram, Usha, Rana, Saleem M, Ranabhat, Chhabi Lal, Rao, Paturi Vishnupriya, Rawaf, Salman, Ray, Sarah E, Rego, Maria Albertina Santiago, Rehm, Jürgen, Reiner, Robert C, Remuzzi, Giuseppe, Renzaho, Andre M N, Resnikoff, Serge, Rezaei, Satar, Rezai, Mohammad Sadegh, Ribeiro, Antonio L, Rivas, Jacqueline Castillo, Rokni, Mohammad Bagher, Ronfani, Luca, Roshandel, Gholamreza, Roth, Gregory A, Rothenbacher, Dietrich, Roy, Ambuj, Rubagotti, Enrico, Ruhago, George Mugambage, Saadat, Soheil, Sabde, Yogesh Damodar, Sachdev, Perminder S, Sadat, Nafis, Safdarian, Mahdi, Safi, Sare, Safiri, Saeid, Sagar, Rajesh, Sahathevan, Ramesh, Sahebkar, Amirhossein, Sahraian, Mohammad Ali, Salama, Joseph, Salamati, Payman, Salomon, Joshua A, Salvi, Sundeep Santosh, Samy, Abdallah M, Sanabria, Juan Ramon, Sanchez-Niño, Maria Dolores, Santos, Itamar S, Santric Milicevic, Milena M, Sarmiento-Suarez, Rodrigo, Sartorius, Benn, Satpathy, Maheswar, Sawhney, Monika, Saxena, Sonia, Saylan, Mete I, Schmidt, Maria Inês, Schneider, Ione J C, Schulhofer-Wohl, Sam, Schutte, Aletta E, Schwebel, David C, Schwendicke, Falk, Seedat, Soraya, Seid, Abdulbasit Musa, Sepanlou, Sadaf G, Servan-Mori, Edson E, Shackelford, Katya Anne, Shaheen, Amira, Shahraz, Saeid, Shaikh, Masood Ali, Shamsipour, Mansour, Shamsizadeh, Morteza, Sharma, Jayendra, Sharma, Rajesh, She, Jun, Shen, Jiabin, Shetty, Balakrishna P, Shi, Peilin, Shibuya, Kenji, Shifa, Girma Temam, Shigematsu, Mika, Shiri, Rahman, Shiue, Ivy, Shrime, Mark G, Sigfusdottir, Inga Dora, Silberberg, Donald H, Silpakit, Naris, Silva, Diego Augusto Santos, Silva, João Pedro, Silveira, Dayane Gabriele Alves, Sindi, Shireen, Singh, Jasvinder A, Singh, Prashant Kumar, Singh, Abhishek, Singh, Virendra, Sinha, Dhirendra Narain, Skarbek, Katarzyna A Kissimova, Skiadaresi, Eirini, Sligar, Amber, Smith, David L, Sobaih, Badr H A, Sobngwi, Eugene, Soneji, Samir, Soriano, Joan B, Sreeramareddy, Chandrashekhar T, Srinivasan, Vinay, Stathopoulou, Vasiliki, Steel, Nicholas, Stein, Dan J, Steiner, Caitlyn, Stöckl, Heidi, Stokes, Mark Andrew, Strong, Mark, Sufiyan, Muawiyyah Babale, Suliankatchi, Rizwan Abdulkader, Sunguya, Bruno F, Sur, Patrick J, Swaminathan, Soumya, Sykes, Bryan L, Szoeke, Cassandra E I, Tabarés-Seisdedos, Rafael, Tadakamadla, Santosh Kumar, Tadese, Fentaw, Tandon, Nikhil, Tanne, David, Tarajia, Musharaf, Tavakkoli, Mohammad, Taveira, Nuno, Tehrani-Banihashemi, Arash, Tekelab, Tesfalidet, Tekle, Dejen Yemane, Temsah, Mohamad-Hani, Terkawi, Abdullah Sulieman, Tesema, Cheru Leshargie, Tesssema, Belay, Theis, Andrew, Thomas, Nihal, Thompson, Alex H, Thomson, Alan J, Thrift, Amanda G, Tiruye, Tenaw Yimer, Tobe-Gai, Ruoyan, Tonelli, Marcello, Topor-Madry, Roman, Topouzis, Fotis, Tortajada, Miguel, Tran, Bach Xuan, Truelsen, Thomas, Trujillo, Ulises, Tsilimparis, Nikolaos, Tuem, Kald Beshir, Tuzcu, Emin Murat, Tyrovolas, Stefanos, Ukwaja, Kingsley Nnanna, Undurraga, Eduardo A, Uthman, Olalekan A, Uzochukwu, Benjamin S Chudi, van Boven, Job F M, Varakin, Yuri Y, Varughese, Santosh, Vasankari, Tommi, Vasconcelos, Ana Maria Nogales, Velasquez, Ilais Moreno, Venketasubramanian, Narayanaswamy, Vidavalur, Ramesh, Violante, Francesco S, Vishnu, Abhishek, Vladimirov, Sergey K, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Vos, Theo, Waid, Jillian L, Wakayo, Tolassa, Wang, Yuan-Pang, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Werdecker, Andrea, Wesana, Joshua, Wijeratne, Tissa, Wilkinson, James D, Wiysonge, Charles Shey, Woldeyes, Belete Getahun, Wolfe, Charles D A, Workicho, Abdulhalik, Workie, Shimelash Bitew, Xavier, Denis, Xu, Gelin, Yaghoubi, Mohsen, Yakob, Bereket, Yalew, Ayalnesh Zemene, Yan, Lijing L, Yano, Yuichiro, Yaseri, Mehdi, Ye, Pengpeng, Yimam, Hassen Hamid, Yip, Paul, Yirsaw, Biruck Desalegn, Yonemoto, Naohiro, Yoon, Seok-Jun, Yotebieng, Marcel, Younis, Mustafa Z, Zaidi, Zoubida, Zaki, Maysaa El Sayed, Zeeb, Hajo, Zenebe, Zerihun Menlkalew, Zerfu, Taddese Alemu, Zhang, Anthony Lin, Zhang, Xueying, Zodpey, Sanjay, Zuhlke, Liesl Joanna, Lopez, Alan D, and Murray, Christopher J L
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12. Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016
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Fullman, Nancy, Barber, Ryan M, Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbas, Kaja M, Abd-Allah, Foad, Abdulkader, Rizwan Suliankatchi, Abdulle, Abdishakur M, Abera, Semaw Ferede, Aboyans, Victor, Abu-Raddad, Laith J, Abu-Rmeileh, Niveen M E, Adedeji, Isaac Akinkunmi, Adetokunboh, Olatunji, Afshin, Ashkan, Agrawal, Anurag, Agrawal, Sutapa, Ahmad Kiadaliri, Aliasghar, Ahmadieh, Hamid, Ahmed, Muktar Beshir, Aichour, Miloud Taki Eddine, Aichour, Amani Nidhal, Aichour, Ibtihel, Aiyar, Sneha, Akinyemi, Rufus Olusola, Akseer, Nadia, Al-Aly, Ziyad, Alam, Khurshid, Alam, Noore, Alasfoor, Deena, Alene, Kefyalew Addis, Alizadeh-Navaei, Reza, Alkerwi, Ala'a, Alla, François, Allebeck, Peter, Allen, Christine, Al-Raddadi, Rajaa, Alsharif, Ubai, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amini, Erfan, Ammar, Walid, Ansari, Hossein, Antonio, Carl Abelardo T, Anwari, Palwasha, Arora, Megha, Artaman, Al, Aryal, Krishna Kumar, Asayesh, Hamid, Asgedom, Solomon Weldegebreal, Assadi, Reza, Atey, Tesfay Mehari, Atre, Sachin R, Avila-Burgos, Leticia, Avokpaho, Euripide Frinel G Arthur, Awasthi, Ashish, Azzopardi, Peter, Bacha, Umar, Badawi, Alaa, Balakrishnan, Kalpana, Bannick, Marlena S, Barac, Aleksandra, Barker-Collo, Suzanne L, Bärnighausen, Till, Barrero, Lope H, Basu, Sanjay, Battle, Katherine E, Baune, Bernhard T, Beardsley, Justin, Bedi, Neeraj, Beghi, Ettore, Béjot, Yannick, Bell, Michelle L, Bennett, Derrick A, Bennett, James R, Bensenor, Isabela M, Berhane, Adugnaw, Berhe, Derbew Fikadu, Bernabé, Eduardo, Betsu, Balem Demtsu, Beuran, Mircea, Beyene, Addisu Shunu, Bhala, Neeraj, Bhansali, Anil, Bhatt, Samir, Bhutta, Zulfiqar A, Bicer, Burcu Kucuk, Bidgoli, Hassan Haghparast, Bikbov, Boris, Bilal, Arebu I, Birungi, Charles, Biryukov, Stan, Bizuayehu, Habtamu Mellie, Blosser, Christopher D, Boneya, Dube Jara, Bose, Dipan, Bou-Orm, Ibrahim R, Brauer, Michael, Breitborde, Nicholas J K, Brugha, Traolach S, Bulto, Lemma Negesa Bulto, Butt, Zahid A, Cahuana-Hurtado, Lucero, Cameron, Ewan, Campuzano, Julio Cesar, Carabin, Hélène, Cárdenas, Rosario, Carrero, Juan Jesus, Carter, Austin, Casey, Daniel C, Castañeda-Orjuela, Carlos A, Castro, Ruben Estanislao, Catalá-López, Ferrán, Cercy, Kelly, Chang, Hsing-Yi, Chang, Jung-Chen, Charlson, Fiona J, Chew, Adrienne, Chisumpa, Vesper Hichilombwe, Chitheer, Abdulaal A, Christensen, Hanne, Christopher, Devasahayam Jesudas, Cirillo, Massimo, Cooper, Cyrus, Criqui, Michael H, Cromwell, Elizabeth A, Crump, John A, Dandona, Lalit, Dandona, Rakhi, Dargan, Paul I, das Neves, José, Davitoiu, Dragos V, de Courten, Barbora, De Steur, Hans, Defo, Barthelemy Kuate, Degenhardt, Louisa, Deiparine, Selina, Deribe, Kebede, deVeber, Gabrielle A, Ding, Eric L, Djalalinia, Shirin, Do, Huyen Phuc, Dokova, Klara, Doku, David Teye, Donkelaar, Aaron van, Dorsey, E Ray, Driscoll, Tim R, Dubey, Manisha, Duncan, Bruce Bartholow, Ebel, Beth E, Ebrahimi, Hedyeh, El-Khatib, Ziad Ziad, Enayati, Ahmadali, Endries, Aman Yesuf, Ermakov, Sergey Petrovich, Erskine, Holly E, Eshrati, Babak, Eskandarieh, Sharareh, Esteghamati, Alireza, Estep, Kara, Faraon, Emerito Jose Aquino, Farinha, Carla Sofia e Sa, Faro, André, Farzadfar, Farshad, Fazeli, Mir Sohail, Feigin, Valery L, Feigl, Andrea B, Fereshtehnejad, Seyed-Mohammad, Fernandes, João C, Ferrari, Alize J, Feyissa, Tesfaye Regassa, Filip, Irina, Fischer, Florian, Fitzmaurice, Christina, Flaxman, Abraham D, Foigt, Nataliya, Foreman, Kyle J, Frank, Tahvi, Franklin, Richard C, Friedman, Joseph, Frostad, Joseph J, Fürst, Thomas, Furtado, Joao M, Gakidou, Emmanuela, Garcia-Basteiro, Alberto L, Gebrehiwot, Tsegaye Tewelde, Geleijnse, Johanna M, Geleto, Ayele, Gemechu, Bikila Lencha, Gething, Peter W, Gibney, Katherine B, Gill, Paramjit Singh, Gillum, Richard F, Giref, Ababi Zergaw, Gishu, Melkamu Dedefo, Giussani, Giorgia, Glenn, Scott D, Godwin, William W, Goldberg, Ellen M, Gona, Philimon N, Goodridge, Amador, Gopalani, Sameer Vali, Goryakin, 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13. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
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Vos, Theo, Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbas, Kaja M, Abd-Allah, Foad, Abdulkader, Rizwan Suliankatchi, Abdulle, Abdishakur M, Abebo, Teshome Abuka, Abera, Semaw Ferede, Aboyans, Victor, Abu-Raddad, Laith J, Ackerman, Ilana N, Adamu, Abdu Abdullahi, Adetokunboh, Olatunji, Afarideh, Mohsen, Afshin, Ashkan, Agarwal, Sanjay Kumar, Aggarwal, Rakesh, Agrawal, Anurag, Agrawal, Sutapa, Ahmadieh, Hamid, Ahmed, Muktar Beshir, Aichour, Miloud Taki Eddine, Aichour, Amani Nidhal, Aichour, Ibtihel, Aiyar, Sneha, Akinyemi, Rufus Olusola, Akseer, Nadia, Al Lami, Faris Hasan, Alahdab, Fares, Al-Aly, Ziyad, Alam, Khurshid, Alam, Noore, Alam, Tahiya, Alasfoor, Deena, Alene, Kefyalew Addis, Ali, Raghib, Alizadeh-Navaei, Reza, Alkerwi, Ala'a, Alla, François, Allebeck, Peter, Allen, Christine, Al-Maskari, Fatma, Al-Raddadi, Rajaa, Alsharif, Ubai, Alsowaidi, Shirina, Altirkawi, Khalid A, Amare, Azmeraw T, Amini, Erfan, Ammar, Walid, Amoako, Yaw Ampem, Andersen, 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Reginald, Quintanilla, Beatriz Paulina Ayala, Rabiee, Rynaz H S, Radfar, Amir, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Afarin, Rahimi-Movaghar, Vafa, Rahman, Mohammad Hifz Ur, Rahman, Mahfuzar, Rai, Rajesh Kumar, Rajsic, Sasa, Ram, Usha, Ranabhat, Chhabi Lal, Rankin, Zane, Rao, Puja C, Rao, Paturi Vishnupriya, Rawaf, Salman, Ray, Sarah E, Reiner, Robert C, Reinig, Nikolas, Reitsma, Marissa B, Remuzzi, Giuseppe, Renzaho, Andre M N, Resnikoff, Serge, Rezaei, Satar, Ribeiro, Antonio L, Ronfani, Luca, Roshandel, Gholamreza, Roth, Gregory A, Roy, Ambuj, Rubagotti, Enrico, Ruhago, George Mugambage, Saadat, Soheil, Sadat, Nafis, Safdarian, Mahdi, Safi, Sare, Safiri, Saeid, Sagar, Rajesh, Sahathevan, Ramesh, Salama, Joseph, Saleem, Huda Omer Ba, Salomon, Joshua A, Salvi, Sundeep Santosh, Samy, Abdallah M, Sanabria, Juan R, Santomauro, Damian, Santos, Itamar S, Santos, João Vasco, Santric Milicevic, Milena M, Sartorius, Benn, Satpathy, Maheswar, Sawhney, Monika, Saxena, Sonia, Schmidt, 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- 2017
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14. Assessing the Shifts: A 5-Year Analysis of Surfactant and Assisted Ventilation Trends in Neonatal Care in the United States (2016-2020).
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Vidavalur, Ramesh
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CHILDBIRTH , *PULMONARY surfactant , *NEONATAL intensive care , *CONFIDENCE intervals , *CROSS-sectional method , *RACE , *ARTIFICIAL respiration , *SEX distribution , *MEDICAL care use , *CHI-squared test , *HOSPITAL care , *DESCRIPTIVE statistics , *STATISTICAL hypothesis testing , *ODDS ratio , *LONGITUDINAL method , *POISSON distribution - Abstract
Background: Respiratory distress syndrome is the most common cause of respiratory problems in preterm infants. Early nasal CPAP, combined with the INSURE method (INtubation-SURfactant- Extubation) as the primary respiratory support approach for preterm infants, has gained popularity over prophylactic surfactant with mechanical ventilation in recent years. Limited evidence exists to understand racial differences in resource usage among preterm infants. Objective: To investigate the trends, gender, and racial differences in the use of surfactant and assisted ventilation for > 6 hours among newborns in the United States. Methods: Using 2016-2020 population-based cohort data for all births from the Centers for Disease Control and Prevention's WONDER natality database, we calculated rates, examined trends, and investigated gender and racial differences for surfactant use and assisted ventilation. Contingency tables analyses and Chi-square calculations were performed to detect differences between the groups with statistical significance set at p<.05. Results: Among >18 million newborn births, overall rates of surfactant use and assisted ventilation for the study period were 4.8 and 15.6 per 1000 live births, respectively. While surfactant use remained similar (p=.99), assisted ventilation rates increased from 13.6 to 17.8 per 1000 live births (p <.0001) during the study period. Subgroup analysis among term infants (37-42 weeks) showed statistically significant increases in surfactant use (4.3 to 5.1 per 1000 live births; p<.0001) and assisted ventilation (26.2 to 38.3 per 1000 live births; p< .0001). Late preterm infants (34-36 weeks GA) had increasing assisted ventilation rates (44 to 59 per 1000 live births; OR: 1.35; p<.0001) and trend toward lower surfactant use (11 to 10/1000 live births; OR: 0.95; p=.010) during the study period. Male and Black infants had the highest utilization rates of surfactant and assisted ventilation. Conclusion: Assisted ventilation rates steadily increased across all gestational ages, while surfactant use remained stable during the study period. Racial and gender differences exist for surfactant use and assisted ventilation needs. Contemporary trends toward "gentle" approaches in early respiratory management and guidelines for surfactant administration might have contributed to the changes in utilization rates. Clinicians and stakeholders should consider such information when allocating assets to hospitals and planning regional perinatal programs. [ABSTRACT FROM AUTHOR]
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- 2023
15. Role of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency and Altered Redox Status in Racial Disparities of Neonatal Outcomes: An Innocent Bystander or Unaccused Accomplice?
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Vidavalur, Ramesh
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RACISM , *EVALUATION of medical care , *NEUROTOXICOLOGY , *PREMATURE infants , *NITRIC-oxide synthases , *SYNDROMES , *HEMOLYSIS & hemolysins , *HYPERBILIRUBINEMIA , *NEONATAL diseases , *COENZYMES , *CELLULAR signal transduction , *OXIDATIVE stress , *OXIDOREDUCTASES , *REACTIVE oxygen species , *OXIDATION-reduction reaction , *DISEASE risk factors , *METABOLISM - Abstract
The article focuses on the prevalence and implications of Glucose-6-phosphate dehydrogenase (G6PD) deficiency, the most common inherited enzymopathy worldwide, emphasizing its connection to prematurity and racial disparities in perinatal outcomes, particularly in African American infants, citing potential risks of hyperbilirubinemia, neurotoxicity, and various morbidities associated with G6PD deficiency in preterm infants.
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- 2023
16. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015
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Pete, Patrick Martial Nkamedjie, Nomura, Marika, Norheim, Ole F, Norman, Paul E, Norrving, Bo, Nyakarahuka, Luke, Ogbo, Felix Akpojene, Ohkubo, Takayoshi, Ojelabi, Foluke Adetola, Olivares, Pedro R, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Opio, John Nelson, Oren, Eyal, Ortiz, Alberto, Osman, Majdi, Ota, Erika, Ozdemir, Raziye, PA, Mahesh, Pain, Amanda, Pandian, Jeyaraj D, Pant, Puspa Raj, Papachristou, Christina, Park, Eun-Kee, Park, Jae-Hyun, Parry, Charles D, Parsaeian, Mahboubeh, Caicedo, Angel J Paternina, Patten, Scott B, Patton, George C, Paul, Vinod K, Pearce, Neil, Pedro, João Mário, Stokic, Ljiljana Pejin, Pereira, David M, Perico, Norberto, Pesudovs, Konrad, Petzold, Max, Phillips, Michael Robert, Piel, Frédéric B, Pillay, Julian David, Plass, Dietrich, Platts-Mills, James A, Polinder, Suzanne, Pope, C Arden, Popova, Svetlana, Poulton, Richie G, Pourmalek, Farshad, Prabhakaran, Dorairaj, Qorbani, Mostafa, Quame-Amaglo, Justice, Quistberg, D Alex, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Vafa, Rahman, Mahfuzar, Rahman, Mohammad Hifz Ur, Rahman, Sajjad Ur, Rai, Rajesh Kumar, Rajavi, Zhale, Rajsic, Sasa, Raju, Murugesan, Rakovac, Ivo, Rana, Saleem M, Ranabhat, Chhabi L, Rangaswamy, Thara, Rao, Puja, Rao, Sowmya R, Refaat, Amany H, Rehm, Jürgen, Reitsma, Marissa B, Remuzzi, Giuseppe, Resnikoff, Serge, Ribeiro, Antonio L, Ricci, Stefano, Blancas, Maria Jesus Rios, Roberts, Bayard, Roca, Anna, Rojas-Rueda, David, Ronfani, Luca, Roshandel, Gholamreza, Rothenbacher, Dietrich, Roy, Ambuj, Roy, Nawal K, Ruhago, George Mugambage, Sagar, Rajesh, Saha, Sukanta, Sahathevan, Ramesh, Saleh, Muhammad Muhammad, Sanabria, Juan R, Sanchez-Niño, Maria Dolores, Sanchez-Riera, Lidia, Santos, Itamar S, Sarmiento-Suarez, Rodrigo, Sartorius, Benn, Satpathy, Maheswar, Savic, Miloje, Sawhney, Monika, Schaub, Michael P, Schmidt, Maria Inês, Schneider, Ione J C, Schöttker, Ben, Schutte, Aletta E, Schwebel, David C, Seedat, Soraya, Sepanlou, Sadaf G, Servan-Mori, Edson E, Shackelford, Katya A, Shaddick, Gavin, Shaheen, Amira, Shahraz, Saeid, Shaikh, Masood Ali, Shakh-Nazarova, Marina, Sharma, Rajesh, She, Jun, Sheikhbahaei, Sara, Shen, Jiabin, Shen, Ziyan, Shepard, Donald S, Sheth, Kevin N, Shetty, Balakrishna P, Shi, Peilin, Shibuya, Kenji, Shin, Min-Jeong, Shiri, Rahman, Shiue, Ivy, Shrime, Mark G, Sigfusdottir, Inga Dora, Silberberg, Donald H, Silva, Diego Augusto Santos, Silveira, Dayane Gabriele Alves, Silverberg, Jonathan I, Simard, Edgar P, Singh, Abhishek, Singh, Gitanjali M, Singh, Jasvinder A, Singh, Om Prakash, Singh, Prashant Kumar, Singh, Virendra, Soneji, Samir, Søreide, Kjetil, Soriano, Joan B, Sposato, Luciano A, Sreeramareddy, Chandrashekhar T, Stathopoulou, Vasiliki, Stein, Dan J, Stein, Murray B, Stranges, Saverio, Stroumpoulis, Konstantinos, Sunguya, Bruno F, Sur, Patrick, Swaminathan, Soumya, Sykes, Bryan L, Szoeke, Cassandra E I, Tabarés-Seisdedos, Rafael, Tabb, Karen M, Takahashi, Ken, Takala, Jukka S, Talongwa, Roberto Tchio, Tandon, Nikhil, Tavakkoli, Mohammad, Taye, Bineyam, Taylor, Hugh R, Ao, Braden J Te, Tedla, Bemnet Amare, Tefera, Worku Mekonnen, Have, Margreet Ten, Terkawi, Abdullah Sulieman, Tesfay, Fisaha Haile, Tessema, Gizachew Assefa, Thomson, Alan J, Thorne-Lyman, Andrew L, Thrift, Amanda G, Thurston, George D, Tillmann, Taavi, Tirschwell, David L, Tonelli, Marcello, Topor-Madry, Roman, Topouzis, Fotis, Towbin, Jeffrey Allen, Traebert, Jefferson, Tran, Bach Xuan, Truelsen, Thomas, Trujillo, Ulises, Tura, Abera Kenay, Tuzcu, Emin Murat, Uchendu, Uche S, Ukwaja, Kingsley N, Undurraga, Eduardo A, Uthman, Olalekan A, Dingenen, Rita Van, van Donkelaar, Aaron, Vasankari, Tommi, Vasconcelos, Ana Maria Nogales, Venketasubramanian, Narayanaswamy, Vidavalur, Ramesh, Vijayakumar, Lakshmi, Villalpando, Salvador, Violante, Francesco S, Vlassov, Vasiliy Victorovich, Wagner, Joseph A, Wagner, Gregory R, Wallin, Mitchell T, Wang, Linhong, Watkins, David A, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Werdecker, Andrea, Westerman, Ronny, White, Richard A, Wijeratne, Tissa, Wilkinson, James D, Williams, Hywel C, Wiysonge, Charles Shey, Woldeyohannes, Solomon Meseret, Wolfe, Charles D A, Won, Sungho, Wong, John Q, Woolf, Anthony D, Xavier, Denis, Xiao, Qingyang, Xu, Gelin, Yakob, Bereket, Yalew, Ayalnesh Zemene, Yan, Lijing L, Yano, Yuichiro, Yaseri, Mehdi, Ye, Pengpeng, Yebyo, Henock Gebremedhin, Yip, Paul, Yirsaw, Biruck Desalegn, Yonemoto, Naohiro, Yonga, Gerald, Younis, Mustafa Z, Yu, Shicheng, Zaidi, Zoubida, Zaki, Maysaa El Sayed, Zannad, Faiez, Zavala, Diego E, Zeeb, Hajo, Zeleke, Berihun M, Zhang, Hao, Zodpey, Sanjay, Zonies, David, Zuhlke, Liesl Joanna, Vos, Theo, Lopez, Alan D, and Murray, Christopher J L
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- 2016
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17. Association of Survival at 22 Weeks’ Gestation With Use of Antenatal Corticosteroids and Mode of Delivery in the United States
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Vidavalur, Ramesh, primary, Hussain, Zeenat, additional, and Hussain, Naveed, additional
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- 2023
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18. Letter to the Editor: "Prevalence of and Factors Associated with Neonatal Seizures in the United States, 2016-2020".
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Vidavalur, Ramesh, Ahuja, Grace, Kreutz, Melissa, Hernandez, Joshua, and Goldstein, Mitchell
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SEIZURES (Medicine) , *DISEASE risk factors , *CHILDREN - Published
- 2024
19. Human and Economic Cost of Disease Burden Due to Congenital Hypothyroidism in India: Too Little, but Not Too Late
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Vidavalur, Ramesh, primary
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- 2022
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20. Valuing Disease Burden Due to Neonatal Encephalopathy and Birth Trauma: A Health Economic Evaluation
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More, Kiran, primary and Vidavalur, Ramesh, additional
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- 2022
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21. A Unique Genomic Variant of HDR Syndrome in Newborn
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Vidavalur, Ramesh and Devapatla, Srisatish
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- 2018
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22. Trends in hospitalizations of newborns with hyperbilirubinemia and kernicterus in United States: an epidemiological study.
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Vidavalur, Ramesh and Devapatla, Srisatish
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JAUNDICE , *HYPERBILIRUBINEMIA , *BLOOD transfusion , *NEWBORN infants , *PREMATURE infants , *NEONATAL jaundice - Abstract
Background: Hyperbilirubinemia is one of the most common diagnosis in newborn nurseries in United States. Universal pre-discharge bilirubin screening decreased the incidence of extreme hyperbilirubinemia and risk of kernicterus. Objectives: We sought to assess temporal population trends of hyperbilirubinemia, kernicterus and usage of phototherapy, intravenous immunoglobulin (IVIG), and exchange transfusion. Design/methods: Data from Healthcare Cost and Utilization Project (HCUP)-the Kids' Inpatient Database (KID) obtained for years 1997-2012. All neonatal discharges with ICD-9 codes for neonatal jaundice (774.2, 774.6), kernicterus (773.4, 774.7) and procedure codes for phototherapy (99.83), IVIG infusion (99.14), exchange transfusion (99.01) were extracted. We compared the trends of diagnosis of hyperbilirubinemia, kernicterus, use of phototherapy, IVIG, and exchange transfusion. Results: During the study period, the proportion of infants diagnosed with hyperbilirubinemia increased by 65% (9.4% vs. 15.5%; p<.001) in term infants and 34.5% (33.5% vs. 45%; p<.001) in preterm infants, respectively. Rate of kernicterus discharges significantly reduced from 7 to 1.9 per 100,000 newborns. Overall, the number of exchange transfusions has decreased by 67% during study period while phototherapy and IVIG use increased by 83% and 170%, respectively. Conclusions: In last two decades, there was a significant decrease in neonatal discharges with a history of exchange transfusion or with a diagnosis of kernicterus. However, there was a significant increase in number of neonates discharged home with a history of phototherapy during birth hospitalization and decreased number of exchange transfusions were observed during the study period. Incremental implementation of universal predischarge bilirubin screening and treatments based on 2004 AAP recommended risk-based strategies might have contributed to timely interventions in infants with significant hyperbilirubinemia. [ABSTRACT FROM AUTHOR]
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- 2022
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23. Economic evaluation of point of care universal newborn screening for glucose-6-Phosphate dehydrogenase deficiency in United States.
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Vidavalur, Ramesh and Bhutani, Vinod K
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NEWBORN screening , *GLUCOSE-6-phosphate dehydrogenase deficiency , *POINT-of-care testing , *GLUCOSE-6-phosphate dehydrogenase , *COST analysis , *COST effectiveness - Abstract
Background and objectives Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is frequent inherited enzymopathy that poses potentially preventable risk for extreme hyperbilirubinemia (EHB) which can, rarely, lead to acute bilirubin encephalopathy, childhood kernicterus and death. We aimed to estimate quality adjusted life years (QALY) lost due to G6PD deficiency associated with EHB and economic costs to best estimate value of universal pre-discharge screening. Methods We did a cost utility analysis for US birth cohort utilizing pre-discharge screening decision tree model to estimate population burden and EHB outcomes, based on literature search and expert opinions. Employing human capital approach, we measured health benefits in terms of QALYs and economic losses. QALYs and costs were discounted at 3%; one-way sensitivity analysis was used for decision variables. Results We determined for USA live births of 3.86 million in 2017, 1464 cases of EHB were estimated to be due to G6PD deficiency (CI 95%; range: 1270–1656) and contributed 2 deaths (CI 95%; range 1.3–3.2) and 14 (CI 95%; range: 9.1–21.5) cases of kernicterus. Over lifetime horizon, the model predicted undiscounted and discounted gains of 165 (102–252) life years; 241 (183–433) QALYs and 16 (9.9–24.5) life years; 89 (67.9–160.5) QALYs, respectively. Assuming 50% effectiveness, benefit cost ratios ranged from 0.19 to 3.42 for diverse operational settings. The cost to prevent a single case of kernicterus was $2.7 to 6.8 million per annum with cost per QALY gained at $35,946 to $89,159. Conclusion At incremental cost-effective threshold of $100,000/life year, pre-discharge screening would be expected to prove cost effective in preventing EHB related morbidities and mortality attributed to G6PD deficiency. [ABSTRACT FROM AUTHOR]
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- 2022
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24. Trends in hospitalizations of newborns with hyperbilirubinemia and kernicterus in United States: an epidemiological study
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Vidavalur, Ramesh, primary and Devapatla, Srisatish, additional
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- 2021
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25. Economic evaluation of point of care universal newborn screening for glucose-6-Phosphate dehydrogenase deficiency in United States
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Vidavalur, Ramesh, primary and Bhutani, Vinod K, additional
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- 2021
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26. Estimated disease burden and lost economic productivity due to glucose-6-phosphate dehydrogenase deficiency in Nigerian newborns
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Vidavalur, Ramesh, primary, Ezeaka, Veronica Chinyere, additional, and Bhutani, Vinod K., additional
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- 2021
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27. Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017
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Lozano, Rafael, Fullman, Nancy, Abate, Degu, Abay, Solomon M, Abbafati, Cristiana, Abbasi, Nooshin, Abbastabar, Hedayat, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abdel-Rahman, Omar, Abdi, Alireza, Abdollahpour, Ibrahim, Abdulkader, Rizwan Suliankatchi, Abebe, Nebiyu Dereje, Abebe, Zegeye, Abejie, Ayenew Negesse, Abera, Semaw F, Abil, Olifan Zewdie, Aboyans, Victor, Abraha, Haftom Niguse, Abrham, Aklilu Roba, Abu-Raddad, Laith Jamal, Abu-Rmeileh, Niveen Me, Abyu, Gebre Y, Accrombessi, Manfred Mario Kokou, Acharya, Dilaram, Acharya, Pawan, Adamu, Abdu A, Adebayo, Oladimeji M, Adedeji, Isaac Akinkunmi, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Adetokunboh, Olatunji O, Adhena, Beyene Meressa, Adhikari, Tara Ballav, Adib, Mina G, Adou, Arsène Kouablan, Adsuar, Jose C, Afarideh, Mohsen, Afshari, Mahdi, Afshin, Ashkan, Agarwal, Gina, Aghayan, Sargis Aghasi, Agius, Dominic, Agrawal, Anurag, Agrawal, Sutapa, Ahmadi, Alireza, Ahmadi, Mehdi, Ahmadieh, Hamid, Ahmed, Muktar Beshir, Ahmed, Sayem, Akalu, Temesgen Yihunie, Akanda, Ali S, Akbari, Mohammad Esmaeil, Akibu, Mohammed, Akinyemi, Rufus Olusola, Akinyemiju, Tomi, Akseer, Nadia, Alahdab, Fares, Al-Aly, Ziyad, Alam, Khurshid, Alam, Tahiya, Albujeer, Ammar, Alebel, Animut, Alene, Kefyalew Addis, Al-Eyadhy, Ayman, Alhabib, Samia, Ali, Raghib, Alijanzadeh, Mehran, Alizadeh-Navaei, Reza, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Alla, François, Allebeck, Peter, Allen, Christine A, Almasi, Ali, Al-Maskari, Fatma, Al-Mekhlafi, Hesham M, Alonso, Jordi, Al-Raddadi, Rajaa M, Alsharif, Ubai, Altirkawi, Khalid, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amenu, Kebede, Amini, Erfan, Ammar, Walid, Anber, Nahla Hamed, Anderson, Jason A, Andrei, Catalina Liliana, Androudi, Sofia, Animut, Megbaru Debalkie, Anjomshoa, Mina, Ansari, Hossein, Ansariadi, Ansariadi, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Anwari, Palwasha, Appiah, Lambert Tetteh, Aremu, Olatunde, Areri, Habtamu Abera, Ärnlöv, Johan, Arora, Monika, Aryal, Krishna K, Asayesh, Hamid, Asfaw, Ephrem Tsegay, Asgedom, Solomon Weldegebreal, Asghar, Rana Jawad, Assadi, Reza, Ataro, Zerihun, Atique, Suleman, Atre, Sachin R, Atteraya, Madhu Sudhan, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide F G A, Awasthi, Ashish, Ayala Quintanilla, Beatriz Paulina, Ayele, Henok Tadesse, Ayele, Yohanes, Ayer, Rakesh, Azarpazhooh, Mahmoud Reza, Azzopardi, Peter S, Azzopardi-Muscat, Natasha, Babalola, Tesleem Kayode, Babazadeh, Arefeh, Badali, Hamid, Badawi, Alaa, Balakrishnan, Kalpana, Bali, Ayele Geleto, Banach, Maciej, Banerjee, Amitava, Banoub, Joseph Adel Mattar, Banstola, Amrit, Barac, Aleksandra, Barboza, Miguel A, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Barrero, Lope H, Barthelemy, Celine M, Bassat, Quique, Basu, Arindam, Basu, Sanjay, Battista, Robert J, Baune, Bernhard T, Baynes, Habtamu Wondifraw, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Beghi, Ettore, Behzadifar, Masoud, Behzadifar, Meysam, Béjot, Yannick, Bekele, Bayu Begashaw, Belachew, Abate Bekele, Belay, Aregawi Gebreyesus, Belay, Saba Abraham, Belay, Yihalem Abebe, Bell, Michelle L, Bello, Aminu K, Bennett, Derrick A, Bensenor, Isabela M, Benzian, Habib, Berhane, Adugnaw, Berhe, Abadi Kidanemariam, Berman, Adam E, Bernabe, Eduardo, Bernstein, Robert S, Bertolacci, Gregory J, Beuran, Mircea, Beyranvand, Tina, Bhala, Neeraj, Bhalla, Ashish, Bhansali, Anil, Bhattarai, Suraj, Bhaumik, Soumyadeep, Bhutta, Zulfiqar A, Biadgo, Belete, Biehl, Molly H, Bijani, Ali, Bikbov, Boris, Bililign, Nigus, Bin Sayeed, Muhammad Shahdaat, Birlik, Sait Mentes, Birungi, Charles, Bisanzio, Donal, Biswas, Tuhin, Bitew, Helen, Bizuneh, Hailemichael, Bjertness, Espen, Bobasa, Eshetu Mulisa, Boufous, Soufiane, Bourne, Rupert, Bozorgmehr, Kayvan, Bragazzi, Nicola Luigi, Brainin, Michael, Brant, Luisa C, Brauer, Michael, Brazinova, Alexandra, Breitborde, Nicholas J K, Briant, Paul Svitil, Britton, Gabrielle, Brugha, Traolach, Bukhman, Gene, Busse, Reinhard, Butt, Zahid A, Cahuana-Hurtado, Lucero, Callender, Charlton SKH, Campos-Nonato, Ismael R, Campuzano Rincon, Julio Cesar, Cano, Jorge, Car, Josip, Car, Mate, Cárdenas, Rosario, Carrero, Juan J, Carter, Austin, Carvalho, Félix, Castañeda-Orjuela, Carlos A, Castillo Rivas, Jacqueline, Castro, Franz, Causey, Kate, Çavlin, Alanur, Cercy, Kelly M, Cerin, Ester, Chaiah, Yazan, Chalek, Julian, Chang, Hsing-Yi, Chang, Jung-Chen, Chattopadhyay, Aparajita, Chattu, Vijay Kumar, Chaturvedi, Pankaj, Chiang, Peggy Pei-Chia, Chin, Ken Lee, Chisumpa, Vesper Hichilombwe, Chitheer, Abdulaal, Choi, Jee-Young J, Chowdhury, Rajiv, Christensen, Hanne, Christopher, Devasahayam J, Chung, Sheng-Chia, Cicuttini, Flavia M, Ciobanu, Liliana G, Cirillo, Massimo, Claro, Rafael M, Claßen, Thomas Khaled Dwayne, Cohen, Aaron J, Collado-Mateo, Daniel, Cooper, Cyrus, Cooper, Leslie Trumbull, Cornaby, Leslie, Cortinovis, Monica, Costa, Megan, Cousin, Ewerton, Cromwell, Elizabeth A, Crowe, Christopher Stephen, Cunningham, Matthew, Daba, Alemneh Kabeta, Dadi, Abel Fekadu, Dandona, Lalit, Dandona, Rakhi, Dang, Anh Kim, Dargan, Paul I, Daryani, Ahmad, Das, Siddharth K, Das Gupta, Rajat, das Neves, José, Dasa, Tamirat Tesfaye, Dash, Aditya Prasad, Davis, Adrian C, Davitoiu, Dragos Virgil, Davletov, Kairat, Dayama, Anand, de Courten, Barbora, De Leo, Diego, De Neve, Jan-Walter, De Steur, Hans, Degefa, Meaza Girma, Degenhardt, Louisa, Degfie, Tizta Tilahun, Deiparine, Selina, Dellavalle, Robert P, Demoz, Gebre Teklemariam, Demtsu, Balem, Denova-Gutiérrez, Edgar, Deribe, Kebede, Dervenis, Nikolaos, Dessie, Getenet Ayalew, Dey, Subhojit, Dharmaratne, Samath D, Dhimal, Meghnath, Dicker, Daniel, Dinberu, Mesfin Tadese, Ding, Eric L, Djalalinia, Shirin, Do, Huyen Phuc, Dokova, Klara, Doku, David Teye, Douwes-Schultz, Dirk, Driscoll, Tim Robert, Duan, Leilei, Dubey, Manisha, Dubljanin, Eleonora, Duken, Eyasu Ejeta, Duncan, Bruce B, Duraes, Andre R, Ebrahimpour, Soheil, Edvardsson, David, El Bcheraoui, Charbel, Eldrenkamp, Erika, El-Khatib, Ziad, Elyazar, Iqbal RF, Enayati, Ahmadali, Endries, Aman Yesuf, Eshrati, Babak, Eskandarieh, Sharareh, Esteghamati, Alireza, Esteghamati, Sadaf, Estep, Kara, Fakhar, Mahdi, Fakhim, Hamed, Fanzo, Jessica, Faramarzi, Mahbobeh, Fareed, Mohammad, Farhadi, Farzaneh, Farid, Talha A, Farinha, Carla Sofia e Sá, Farioli, Andrea, Faro, Andre, Farvid, Maryam S, Farzadfar, Farshad, Farzaei, Mohammad Hosein, Farzam, Hossein, Fazaeli, Ali Akbar, Fazeli, Mir Sohail, Feigin, Valery L, Feigl, Andrea B, Fekadu, Wubalem, Feldman, Rachel, Fentahun, Netsanet, Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Fernandes, Joao C, Feyissa, Garumma Tolu, Fijabi, Daniel Obadare, Filip, Irina, Finegold, Samuel, Finger, Jonas David, Fischer, Florian, Fitzmaurice, Christina, Flor, Luisa Sorio, Foigt, Nataliya A, Foreman, Kyle J, Frank, Tahvi D, Franklin, Richard Charles, Fukumoto, Takeshi, Fukutaki, Kai, Fuller, John E, Fürst, Thomas, Furtado, João M, Gakidou, Emmanuela, Gallus, Silvano, Gankpe, Fortune Gbetoho, Gansevoort, Ron T, Garcia, Ana Cristina, Garcia-Basteiro, Alberto L, Garcia-Gordillo, Miguel A, Gardner, William M, Gebre, Abadi Kahsu, Gebre, Teshome, Gebregergs, Gebremedhin Berhe, Gebrehiwot, Tsegaye Tewelde, Gebremedhin, Amanuel Tesfay, Gebremichael, Bereket, Gebremichael, Teklu Gebrehiwo, Gelano, Tilayie Feto, Geleijnse, Johanna M, Geramo, Yilma Chisha Dea, Getachew, Sefonias, Gething, Peter W, Gezae, Kebede Embaye, Ghadami, Mohammad Rasoul, Ghadimi, Reza, Ghadiri, Keyghobad, Ghasemi-Kasman, Maryam, Ghiasvand, Hesam, Ghimire, Mamata, Ghoshal, Aloke Gopal, Giampaoli, Simona, Gill, Paramjit Singh, Gill, Tiffany K, Giussani, Giorgia, Gnedovskaya, Elena V, Goldberg, Ellen M, Goli, Srinivas, Gona, Philimon N, Goodridge, Amador, Gopalani, Sameer Vali, Gorman, Taren M, Goto, Atsushi, Goulart, Alessandra C, Goulart, Bárbara Niegia Garcia, Grada, Ayman, Griswold, Max G, Grosso, Giuseppe, Gugnani, Harish Chander C, Guillemin, Francis, Guimaraes, Andre Luiz Sena, Guo, 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GENDER-DIFFERENCES ,SUICIDE ,Medicine (all) ,Burden of Disease Study 2017 ,SDG ,CONSUMPTION ,11 Medical And Health Sciences ,GBD, Sustainable Development Goals ,PREVENTION ,ALCOHOL-USE ,CARDIOVASCULAR-DISEASE ,SMOKING PREVALENCE ,General & Internal Medicine ,factors risk ,Medicine and Health Sciences ,Human medicine ,CESSATION ,PERSPECTIVE ,TRANSITION - Abstract
Background Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of "leaving no one behind", it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017), we measured progress on 41 of 52 health -related SDG indicators and estimated the health-related SDG index for 195 countries and territories for the period 1990-2017, projected indicators to 2030, and analysed global attainment. Methods We measured progress on 41 health-related S DG indicators from 1990 to 2017, an increase of four indicators since GBD 2016 (new indicators were health worker density, sexual violence by non-intimate partners, population census status, and prevalence of physical and sexual violence [reported separately]). We also improved the measurement of several previously reported indicators. We constructed national-level estimates and, for a subset of health-related SDGs, examined indicator-level differences by sex and Socio-demographic Index (SDI) quintile. We also did subnational assessments of performance for selected countries. To construct the health related SDG index, we transformed the value for each indicator on a scale of 0-100, with 0 as the 2.5th percentile and 100 as the 97.5th percentile of 1000 draws calculated from 1990 to 2030, and took the geometric mean of the scaled indicators by target. To generate projections through 2030, we used a forecasting framework that drew estimates from the broader GBD study and used weighted averages of indicator-specific and country-specific annualised rates of change from 1990 to 2017 to inform future estimates. We assessed attainment of indicators with defined targets in two ways: first, using mean values projected for 2030, and then using the probability of attainment in 2030 calculated from 1000 draws. We also did a global attainment analysis of the feasibility of attaining SDG targets on the basis of past trends. Using 2015 global averages of indicators with defined SDG targets, we calculated the global annualised rates of change required from 2015 to 2030 to meet these targets, and then identified in what percentiles the required global annualised rates of change fell in the distribution of country-level rates of change from 1990 to 2015. We took the mean of these global percentile values across indicators and applied the past rate of change at this mean global percentile to all health-related SDG indicators, irrespective of target definition, to estimate the equivalent 2030 global average value and percentage change from 2015 to 2030 for each indicator. Findings The global median health-related SDG index in 2017 was 59.4 (IQR 35.4-67.3), ranging from a low of 11.6 (95% uncertainty interval 9.6-14.0) to a high of 84.9 (83.1-86.7). SDG index values in countries assessed at the subnational level varied substantially particularly in China and India, although scores in Japan and the UK were more homogeneous. Indicators also varied by SDI quintile and sex, with males having worse outcomes than females for non-communicable disease (NCD) mortality, alcohol use, and smoking, among others. Most countries were projected to have a higher health-related SDG index in 2030 than in 2017, while country-level probabilities of attainment by 2030 varied widely by indicator. Under-5 mortality, neonatal mortality, maternal mortality ratio, and malaria indicators had the most countries with at least 95% probability of target attainment. Other indicators, including NCD mortality and suicide mortality, had no countries projected to meet corresponding SDG targets on the basis of projected mean values for 2030 but showed some probability of attaimnent by 2030. For some indicators, including child malnutrition, several infectious diseases, and most violence measures, the annualised rates of change required to meet SDG targets far exceeded the pace of progress achieved by any country in the recent past. We found that applying the mean global annualised rate of change to indicators without defined targets would equate to about 19% and 22% reductions in global smoking and alcohol consumption, respectively; a 47% decline in adolescent birth rates; and a more than 85% increase in health worker density per 1000 population by 2030. Interpretation The GBD study offers a unique, robust platform for monitoring the health -related SDGs across demographic and geographic dimensions. Our findings underscore the importance of increased collection and analysis of disaggregated data and highlight where more deliberate design or targeting of interventions could accelerate progress in attaining the SDGs. Current projections show that many health -related SDG indicators, NCDs, NCD-related risks, and violence -related indicators will require a concerted shift away from what might have driven past gains curative interventions in the case of NCDs towards multisectoral, prevention -oriented policy action and investments to achieve SDG aims. Notably, several targets, if they are to be met by 2030, demand a pace of progress that no country has achieved in the recent past. The future is fundamentally uncertain, and no model can fully predict what breakthroughs or events might alter the course of the S DGs. What is clear is that our actions or inaction today will ultimately dictate how close the world, collectively, can get to leaving no one behind by 2030. Copyright (C) 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
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28. Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017
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Child mortality ,Alnæmi ,Dánartíðni ,Heilsufar ,GBD ,Börn ,Dauði ,Almennar lyflækningar ,Fullorðnir ,General & Internal Medicine ,parasitic diseases ,Psychology ,age-specific mortality ,Estimating adult mortality ,Medicine (all) ,HIV ,11 Medical And Health Sciences ,General Medicine ,All-cause mortality ,humanities ,Countries ,Death ,mortality, national ,Sálfræði ,Health ,GBD, mortality ,Human medicine ,Trends - Abstract
The content is solely the responsibility of the authors and does not necessarily represent the official views of the funders. Data for this research was provided by MEASURE Evaluation, funded by the United States Agency for International Development (USAID). Views expressed do not necessarily reflect those of USAID, the US Government, or MEASURE Evaluation. The Palestinian Central Bureau of Statistics granted the researchers access to relevant data in accordance with licence no. SLN2014-3-170, after subjecting data to processing aiming to preserve the confidentiality of individual data in accordance with the General Statistics Law-2000. The researchers are solely responsible for the conclusions and inferences drawn upon available data., Background Assessments of age-specific mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Affairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). Previous iterations of the GBD used population estimates from UNPOP, which were not derived in a way that was internally consistent with the estimates of the numbers of deaths in the GBD. The present iteration of the GBD, GBD 2017, improves on previous assessments and provides timely estimates of the mortality experience of populations globally. Methods The GBD uses all available data to produce estimates of mortality rates between 1950 and 2017 for 23 age groups, both sexes, and 918 locations, including 195 countries and territories and subnational locations for 16 countries. Data used include vital registration systems, sample registration systems, household surveys (complete birth histories, summary birth histories, sibling histories), censuses (summary birth histories, household deaths), and Demographic Surveillance Sites. In total, this analysis used 8259 data sources. Estimates of the probability of death between birth and the age of 5 years and between ages 15 and 60 years are generated and then input into a model life table system to produce complete life tables for all locations and years. Fatal discontinuities and mortality due to HIV/AIDS are analysed separately and then incorporated into the estimation. We analyse the relationship between age-specific mortality and development status using the Socio-demographic Index, a composite measure based on fertility under the age of 25 years, education, and income. There are four main methodological improvements in GBD 2017 compared with GBD 2016: 622 additional data sources have been incorporated; new estimates of population, generated by the GBD study, are used; statistical methods used in different components of the analysis have been further standardised and improved; and the analysis has been extended backwards in time by two decades to start in 1950. Findings Globally, 18·7% (95% uncertainty interval 18·4–19·0) of deaths were registered in 1950 and that proportion has been steadily increasing since, with 58·8% (58·2–59·3) of all deaths being registered in 2015. At the global level, between 1950 and 2017, life expectancy increased from 48·1 years (46·5–49·6) to 70·5 years (70·1–70·8) for men and from 52·9 years (51·7–54·0) to 75·6 years (75·3–75·9) for women. Despite this overall progress, there remains substantial variation in life expectancy at birth in 2017, which ranges from 49·1 years (46·5–51·7) for men in the Central African Republic to 87·6 years (86·9–88·1) among women in Singapore. The greatest progress across age groups was for children younger than 5 years; under-5 mortality dropped from 216·0 deaths (196·3–238·1) per 1000 livebirths in 1950 to 38·9 deaths (35·6–42·83) per 1000 livebirths in 2017, with huge reductions across countries. Nevertheless, there were still 5·4 million (5·2–5·6) deaths among children younger than 5 years in the world in 2017. Progress has been less pronounced and more variable for adults, especially for adult males, who had stagnant or increasing mortality rates in several countries. The gap between male and female life expectancy between 1950 and 2017, while relatively stable at the global level, shows distinctive patterns across super-regions and has consistently been the largest in central Europe, eastern Europe, and central Asia, and smallest in south Asia. Performance was also variable across countries and time in observed mortality rates compared with those expected on the basis of development. Interpretation This analysis of age-sex-specific mortality shows that there are remarkably complex patterns in population mortality across countries. The findings of this study highlight global successes, such as the large decline in under-5 mortality, which reflects significant local, national, and global commitment and investment over several decades. However, they also bring attention to mortality patterns that are a cause for concern, particularly among adult men and, to a lesser extent, women, whose mortality rates have stagnated in many countries over the time period of this study, and in some cases are increasing., Research reported in this publication was supported by the Bill & Melinda Gates Foundation, the University of Melbourne, Public Health England, the Norwegian Institute of Public Health, St. Jude Children's Research Hospital, the National Institute on Aging of the National Institutes of Health (award P30AG047845), and the National Institute of Mental Health of the National Institutes of Health (award R01MH110163).
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- 2018
29. Trends in infant mortality due to haemolytic disease and other perinatal jaundice in the USA, 1999–2020
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Vidavalur, Ramesh and Bhutani, Vinod K
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- 2024
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30. Sildenafil-mediated neovascularization and protection against myocardial ischaemia reperfusion injury in rats: role of VEGF/angiopoietin-1
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Koneru, Srikanth, Varma Penumathsa, Suresh, Thirunavukkarasu, Mahesh, Vidavalur, Ramesh, Zhan, Lijun, Singal, Pawan K., Engelman, Richard M, Das, Dipak K, and Maulik, Nilanjana
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- 2008
31. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
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Chhabi Lal, Rangaswamy, Thara, Rankin, Zane, Rao, Paturi Vishnupriya, Rao, Puja C, Rawaf, Salman, Ray, Sarah E, Reiner, Robert C, Reinig, Nikola, Reitsma, Marissa, Remuzzi, Giuseppe, Renzaho, Andre M N, Resnikoff, Serge, Rezaei, Satar, Ribeiro, Antonio L, Rivas, Jacqueline Castillo, Roba, Hirbo Shore, Robinson, Stephen R, Rojas-Rueda, David, Rokni, Mohammad Bagher, Ronfani, Luca, Roshandel, Gholamreza, Roth, Gregory A, Rothenbacher, Dietrich, Roy, Ambuj, Rubagotti, Enrico, Ruhago, George Mugambage, Saadat, Soheil, Safdarian, Mahdi, Safiri, Saeid, Sagar, Rajesh, Sahathevan, Ramesh, Sahraian, Mohammad Ali, Salama, Joseph, Saleh, Muhammad Muhammad, Salomon, Joshua A, Salvi, Sundeep Santosh, Samy, Abdallah M, Sanabria, Juan Ramon, Sanchez-Niño, Maria Dolore, Santomauro, Damian, Santos, João Vasco, Santos, Itamar S, Santric Milicevic, Milena M, Sartorius, Benn, Satpathy, Maheswar, Sawhney, Monika, Saxena, Sonia, Schelonka, Kathryn, Schmidt, Maria Inê, Schneider, Ione J C, Schöttker, Ben, 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Johnson, C, Johnson, S, Jonas, J, Jürisson, M, Kabir, Z, Kadel, R, Kahsay, A, Kamal, R, Kar, C, Karam, N, Karch, A, Karema, C, Karimi, S, Karimkhani, C, Kasaeian, A, Kassa, G, Kassaw, N, Kassebaum, N, Kastor, A, Katikireddi, S, Kaul, A, Kawakami, N, Keiyoro, P, Kemmer, L, Kengne, A, Keren, A, Kesavachandran, C, Khader, Y, Khalil, I, Khan, E, Khang, Y, Khoja, A, Khosravi, A, Khubchandani, J, Kiadaliri, A, Kieling, C, Kim, Y, Kim, D, Kimokoti, R, Kinfu, Y, Kisa, A, Kissimova-Skarbek, K, Kissoon, N, Kivimaki, M, Knudsen, A, Kokubo, Y, Kolte, D, Kopec, J, Kosen, S, Kotsakis, G, Koul, P, Koyanagi, A, Kravchenko, M, Krohn, K, Kumar, G, Kumar, P, Kyu, H, Lager, A, Lal, D, Lalloo, R, Lallukka, T, Lambert, N, Lan, Q, Lansingh, V, Larsson, A, Leasher, J, Lee, P, Leigh, J, Leshargie, C, Leung, J, Leung, R, Levi, M, Li, Y, Liang, X, Liben, M, Lim, S, Linn, S, Liu, P, Liu, A, Liu, S, Liu, Y, Lodha, R, Logroscino, G, Looker, K, Lopez, A, Lorkowski, S, Lotufo, P, Lozano, R, Lucas, T, Lunevicius, R, 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S, Musa, K, Nachega, J, Nagel, G, Naghavi, M, Naheed, A, Naidoo, K, Nangia, V, Nasher, J, Natarajan, G, Negasa, D, Negoi, R, Negoi, I, Newton, C, Ngunjiri, J, Nguyen, C, Nguyen, Q, Nguyen, T, Nguyen, G, Nguyen, M, Nichols, E, Ningrum, D, Nong, V, Norheim, O, Norrving, B, Noubiap, J, Nyandwi, A, Obermeyer, C, O'Donnell, M, Ogbo, F, Oh, I, Okoro, A, Oladimeji, O, Olagunju, A, Olagunju, T, Olsen, H, Olusanya, B, Olusanya, J, Ong, K, Opio, J, Oren, E, Ortiz, A, Osborne, R, Osgood-Zimmerman, A, Osman, M, Ota, E, Owolabi, M, Pa, M, Pacella, R, Panda, B, Pandian, J, Papachristou, C, Park, E, Parry, C, Parsaeian, M, Patil, S, Patten, S, Patton, G, Paudel, D, Paulson, K, Pearce, N, Pereira, D, Perez, K, Perico, N, Pesudovs, K, Peterson, C, Petri, W, Petzold, M, Phillips, M, Phipps, G, Pigott, D, Pillay, J, Pinho, C, Piradov, M, Plass, D, Pletcher, M, Popova, S, Poulton, R, Pourmalek, F, Prabhakaran, D, Prasad, N, Purcell, C, Purwar, M, Qorbani, M, Quintanilla, B, Rabiee, R, Radfar, A, Rafay, A, 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- Subjects
Male ,Dánarmein ,AUSTRALIA ,GBD, disability-adjusted life-years (DALYs) ,Heilsufar ,Lífslíkur ,Epidemiology ,Life expectancy ,Diseases ,Global Health ,THERAPY ,Global Burden of Disease ,Residence Characteristics ,Fullorðnir ,Cause of Death ,Medicine and Health Sciences ,Psychology ,Konur ,Aged, 80 and over ,Tölfræði ,PLASMODIUM-FALCIPARUM ,Aldraðir ,Sjúkdómar ,Medicine (all) ,Fatlaðir ,Men ,Þjóðir ,11 Medical And Health Sciences ,ASSOCIATION ,Middle Aged ,Health policy ,PREVALENCE ,Sálfræði ,disability-adjusted life-years (DALYs) ,Female ,Lýðheilsa ,Quality-Adjusted Life Years ,Life Sciences & Biomedicine ,Global Health Metrics ,Adult ,AFRICA ,Quality of life ,People with disabilities ,GBD ,WEIGHTS ,Social ecology ,Lífsgæði ,Communicable Diseases ,World health/statistics ,Age Distribution ,Life Expectancy ,Medicine, General & Internal ,SDG 3 - Good Health and Well-being ,General & Internal Medicine ,Heilbrigðisstefna ,Humans ,Adults ,Disabled Persons ,Women ,Sex Distribution ,Mortality ,Noncommunicable Diseases ,Aged ,Science & Technology ,Faraldsfræði ,MORTALITY ,Wounds and injuries ,EPIDEMIOLOGIC TRANSITION ,HIV ,Áverkar ,Karlar ,Wounds and Injuries ,Félagshagfræði ,Older people - Abstract
Correction in: LANCET Volume: 390 Issue: 10106 Pages: E38-E38 Published: OCT 28 2017, Background Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures to monitor such changes in population health: disability-adjusted life-years (DALYs) and healthy life expectancy (HALE). We used these measures to track trends and benchmark progress compared with expected trends on the basis of the Socio-demographic Index (SDI). Methods We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 countries and territories from 1990 to 2016. We calculated DALYs by summing years of life lost and years of life lived with disability for each location, age group, sex, and year. We estimated HALE using age-specific death rates and years of life lived with disability per capita. We explored how DALYs and HALE differed from expected trends when compared with the SDI: the geometric mean of income per person, educational attainment in the population older than age 15 years, and total fertility rate. Findings The highest globally observed HALE at birth for both women and men was in Singapore, at 75.2 years (95% uncertainty interval 71.9-78.6) for females and 72.0 years (68.8-75.1) for males. The lowest for females was in the Central African Republic (45.6 years [42.0-49.5]) and for males was in Lesotho (41.5 years [39.0-44.0]). From 1990 to 2016, global HALE increased by an average of 6.24 years (5.97-6.48) for both sexes combined. Global HALE increased by 6.04 years (5.74-6.27) for males and 6.49 years (6.08-6.77) for females, whereas HALE at age 65 years increased by 1.78 years (1.61-1.93) for males and 1.96 years (1.69-2.13) for females. Total global DALYs remained largely unchanged from 1990 to 2016 (-2.3% [-5.9 to 0.9]), with decreases in communicable, maternal, neonatal, and nutritional (CMNN) disease DALYs offset by increased DALYs due to non-communicable diseases (NCDs). The exemplars, calculated as the five lowest ratios of observed to expected age-standardised DALY rates in 2016, were Nicaragua, Costa Rica, the Maldives, Peru, and Israel. The leading three causes of DALYs globally were ischaemic heart disease, cerebrovascular disease, and lower respiratory infections, comprising 16.1% of all DALYs. Total DALYs and age-standardised DALY rates due to most CMNN causes decreased from 1990 to 2016. Conversely, the total DALY burden rose for most NCDs; however, age-standardised DALY rates due to NCDs declined globally. Interpretation At a global level, DALYs and HALE continue to show improvements. At the same time, we observe that many populations are facing growing functional health loss. Rising SDI was associated with increases in cumulative years of life lived with disability and decreases in CMNN DALYs offset by increased NCD DALYs. Relative compression of morbidity highlights the importance of continued health interventions, which has changed in most locations in pace with the gross domestic product per person, education, and family planning. The analysis of DALYs and HALE and their relationship to SDI represents a robust framework with which to benchmark location-specific health performance. Country-specific drivers of disease burden, particularly for causes with higher-than-expected DALYs, should inform health policies, health system improvement initiatives, targeted prevention efforts, and development assistance for health, including financial and research investments for all countries, regardless of their level of sociodemographic development. The presence of countries that substantially outperform others suggests the need for increased scrutiny for proven examples of best practices, which can help to extend gains, whereas the presence of underperforming countries suggests the need for devotion of extra attention to health systems that need more robust support., Bill & Melinda Gates Foundation
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- 2017
32. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016: a systematic analysis for the Global Burden of Disease Study 2016
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Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbas, Kaja M., Abd-Allah, Foad, Abera, Semaw Ferede, Abraha, Haftom Niguse, Abu-Raddad, Laith J., Abu-Rmeileh, Niveen M. 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I., Tabarés-Seisdedos, Rafael, Tadakamadla, Santosh Kumar, Tadese, Fentaw, Tandon, Nikhil, Tanne, David, Tarajia, Musharaf, Tavakkoli, Mohammad, Taveira, Nuno, Tehrani-Banihashemi, Arash, Tekelab, Tesfalidet, Tekle, Dejen Yemane, Temsah, Mohamad-Hani, Terkawi, Abdullah Sulieman, Tesema, Cheru Leshargie, Tesssema, Belay, Theis, Andrew, Thomas, Nihal, Thompson, Alex H., Thomson, Alan J., Thrift, Amanda G., Tiruye, Tenaw Yimer, Tobe-Gai, Ruoyan, Tonelli, Marcello, Topor-Madry, Roman, Topouzis, Fotis, Tortajada, Miguel, Tran, Bach Xuan, Truelsen, Thomas, Trujillo, Ulises, Tsilimparis, Nikolaos, Tuem, Kald Beshir, Tuzcu, Emin Murat, Tyrovolas, Stefanos, Ukwaja, Kingsley Nnanna, Undurraga, Eduardo A., Uthman, Olalekan A., Uzochukwu, Benjamin S. Chudi, van Boven, Job F. M., Varakin, Yuri Y., Varughese, Santosh, Vasankari, Tommi, Vasconcelos, Ana Maria Nogales, Velasquez, Ilais Moreno, Venketasubramanian, Narayanaswamy, Vidavalur, Ramesh, Violante, Francesco S., Vishnu, Abhishek, Vladimirov, Sergey K., Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Vos, Theo, Waid, Jillian L., Wakayo, Tolassa, Wang, Haidong, Wang, Yuan-Pang, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G., Werdecker, Andrea, Wesana, Joshua, Wijeratne, Tissa, Wilkinson, James D., Wiysonge, Charles Shey, Woldeyes, Belete Getahun, Wolfe, Charles D. A., Workicho, Abdulhalik, Workie, Shimelash Bitew, Xavier, Denis, Xu, Gelin, Yaghoubi, Mohsen, Yakob, Bereket, Yalew, Ayalnesh Zemene, Yan, Lijing L., Yano, Yuichiro, Yaseri, Mehdi, Ye, Pengpeng, Yimam, Hassen Hamid, Yip, Paul, Yirsaw, Biruck Desalegn, Yonemoto, Naohiro, Yoon, Seok-Jun, Yotebieng, Marcel, Younis, Mustafa Z., Zaidi, Zoubida, Zaki, Maysaa El Sayed, Zeeb, Hajo, Zenebe, Zerihun Menlkalew, Zerfu, Taddese Alemu, Zhang, Anthony Lin, Zhang, Xueying, Zodpey, Sanjay, Zuhlke, Liesl Joanna, HASH(0x5651ca1ecb00), Viðskiptadeild (HR), School of Business (RU), Háskólinn í Reykjavík, Reykjavik University, Wang, Haidong, Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbas, Kaja M., Abd-Allah, Foad, Abera, Semaw Ferede, Abraha, Haftom Niguse, Abu-Raddad, Laith J., Abu-Rmeileh, Niveen M.E., Adedeji, Isaac Akinkunmi, Adedoyin, Rufus Adesoji, Adetifa, Ifedayo Morayo O., Adetokunboh, Olatunji, Afshin, Ashkan, Aggarwal, Rakesh, Agrawal, Anurag, Agrawal, Sutapa, Ahmad Kiadaliri, Aliasghar, Ahmed, Muktar Beshir, Aichour, Amani Nidhal, Aichour, Ibthiel, Aichour, Miloud Taki Eddine, Aiyar, Sneha, Akanda, Ali Shafqat, Akinyemiju, Tomi F., Akseer, Nadia, Al-Eyadhy, Ayman, Al Lami, Faris Hasan, Alabed, Samer, Alahdab, Fare, Al-Aly, Ziyad, Alam, Khurshid, Alam, Noore, Alasfoor, Deena, Aldridge, Robert William, Alene, Kefyalew Addi, Alhabib, Samia, Ali, Raghib, Alizadeh-Navaei, Reza, Aljunid, Syed M., Alkaabi, Juma M., Alkerwi, Ala'a, Alla, Françoi, Allam, Shalini D., Allebeck, Peter, Al-Raddadi, Rajaa, Alsharif, Ubai, Altirkawi, Khalid A., Martin, Elena Alvarez, Alvis-Guzman, Nelson, Amare, Azmeraw T., Ameh, Emmanuel A., Amini, Erfan, Ammar, Walid, Amoako, Yaw Ampem, Anber, Nahla, Andrei, Catalina Liliana, Androudi, Sofia, Ansari, Hossein, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T., Anwari, Palwasha, Ärnlöv, Johan, Arora, Megha, Artaman, Al, Aryal, Krishna Kumar, Asayesh, Hamid, Asgedom, Solomon Weldegebreal, Asghar, Rana Jawad, Assadi, Reza, Atey, Tesfay Mehari, Atre, Sachin R., Avila-Burgos, Leticia, Avokpaho, Euripide Frinel G. Arthur, Awasthi, Ashish, Ayala Quintanilla, Beatriz Paulina, Babalola, Tesleem Kayode, Bacha, Umar, Badawi, Alaa, Balakrishnan, Kalpana, Balalla, Shivanthi, Barac, Aleksandra, Barber, Ryan M., Barboza, Miguel A., Barker-Collo, Suzanne L., Bärnighausen, Till, Barquera, Simon, Barregard, Lar, Barrero, Lope H., Baune, Bernhard T., Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Beghi, Ettore, Béjot, Yannick, Bekele, Bayu Begashaw, Bell, Michelle L., Bello, Aminu K., Bennett, Derrick A., Bennett, James R., Bensenor, Isabela M., Benson, Jennifer, Berhane, Adugnaw, Berhe, Derbew Fikadu, Bernabé, Eduardo, Beuran, Mircea, Beyene, Addisu Shunu, Bhala, Neeraj, Bhansali, Anil, Bhaumik, Soumyadeep, Bhutta, Zulfiqar A., Bikbov, Bori, Birungi, Charle, Biryukov, Stan, Bisanzio, Donal, Bizuayehu, Habtamu Mellie, Bjerregaard, Peter, Blosser, Christopher D., Boneya, Dube Jara, Boufous, Soufiane, Bourne, Rupert R.A., Brazinova, Alexandra, Breitborde, Nicholas J.K., Brenner, Hermann, Brugha, Traolach S., Bukhman, Gene, Bulto, Lemma Negesa Bulto, Bumgarner, Blair Randal, Burch, Michael, Butt, Zahid A., Cahill, Leah E., Cahuana-Hurtado, Lucero, Campos-Nonato, Ismael Ricardo, Car, Josip, Car, Mate, Cárdenas, Rosario, Carpenter, David O., Carrero, Juan Jesu, Carter, Austin, Castañeda-Orjuela, Carlos A., Castillo Rivas, Jacqueline, Castro, Franz F., Castro, Ruben Estanislao, Catalá-López, Ferrán, Chen, Honglei, Chiang, Peggy Pei-Chia, Chibalabala, Mirriam, Chisumpa, Vesper Hichilombwe, Chitheer, Abdulaal A., Choi, Jee-Young Jasmine, Christensen, Hanne, Christopher, Devasahayam Jesuda, Ciobanu, Liliana G., Cirillo, Massimo, Cohen, Aaron J., Colquhoun, Samantha M., Coresh, Josef, Criqui, Michael H., Cromwell, Elizabeth A., Crump, John A., Dandona, Lalit, Dandona, Rakhi, Dargan, Paul I., Das Neves, José, Davey, Gail, Davitoiu, Dragos V., Davletov, Kairat, De Courten, Barbora, De Leo, Diego, Degenhardt, Louisa, Deiparine, Selina, Dellavalle, Robert P., Deribe, Kebede, Deribew, Amare, Des Jarlais, Don C., Dey, Subhojit, Dharmaratne, Samath D., Dherani, Mukesh K., Diaz-Torné, Cesar, Ding, Eric L., Dixit, Priyanka, Djalalinia, Shirin, Do, Huyen Phuc, Doku, David Teye, Donnelly, Christl Ann, Dos Santos, Kadine Priscila Bender, Douwes-Schultz, Dirk, Driscoll, Tim R., Duan, Leilei, Dubey, Manisha, Duncan, Bruce Bartholow, Dwivedi, Laxmi Kant, Ebrahimi, Hedyeh, El Bcheraoui, Charbel, Ellingsen, Christian Lycke, Enayati, Ahmadali, Endries, Aman Yesuf, Ermakov, Sergey Petrovich, Eshetie, Setegn, Eshrati, Babak, Eskandarieh, Sharareh, Esteghamati, Alireza, Estep, Kara, Fanuel, Fanuel Belayneh Bekele, Faro, André, Farvid, Maryam S., Farzadfar, Farshad, Feigin, Valery L., Fereshtehnejad, Seyed-Mohammad, Fernandes, Jefferson G., Fernandes, João C., Feyissa, Tesfaye Regassa, Filip, Irina, Fischer, Florian, Foigt, Nataliya, Foreman, Kyle J., Frank, Tahvi, Franklin, Richard C., Fraser, Maya, Friedman, Joseph, Frostad, Joseph J., Fullman, Nancy, Fürst, Thoma, Furtado, Joao M., Futran, Neal D., Gakidou, Emmanuela, Gambashidze, Ketevan, Gamkrelidze, Amiran, Gankpé, Fortuné Gbètoho, Garcia-Basteiro, Alberto L., Gebregergs, Gebremedhin Berhe, Gebrehiwot, Tsegaye Tewelde, Gebrekidan, Kahsu Gebrekirsto, Gebremichael, Mengistu Welday, Gelaye, Amha Admasie, Geleijnse, Johanna M., Gemechu, Bikila Lencha, Gemechu, Kasiye Shiferaw, Genova-Maleras, Ricard, Gesesew, Hailay Abrha, Gething, Peter W., Gibney, Katherine B., Gill, Paramjit Singh, Gillum, Richard F., Giref, Ababi Zergaw, Girma, Bedilu Weji, Giussani, Giorgia, Goenka, Shifalika, Gomez, Beatriz, Gona, Philimon N., Gopalani, Sameer Vali, Goulart, Alessandra Carvalho, Graetz, Nichola, Gugnani, Harish Chander, Gupta, Prakash C., Gupta, Rahul, Gupta, Rajeev, Gupta, Tanush, Gupta, Vipin, Haagsma, Juanita A., Hafezi-Nejad, Nima, Haghparast Bidgoli, Hassan, Hakuzimana, Alex, Halasa, Yara A., Hamadeh, Randah Ribhi, Hambisa, Mitiku Teshome, Hamidi, Samer, Hammami, Mouhanad, Hancock, Jamie, Handal, Alexis J., Hankey, Graeme J., Hao, Yuantao, Harb, Hilda L., Hareri, Habtamu Abera, Harikrishnan, Sivadasanpillai, Haro, Josep Maria, Hassanvand, Mohammad Sadegh, Havmoeller, Rasmu, Hay, Roderick J., Hay, Simon I., He, Fei, Heredia-Pi, Ileana Beatriz, Herteliu, Claudiu, Hilawe, Esayas Haregot, Hoek, Hans W., Horita, Nobuyuki, Hosgood, H. Dean, Hostiuc, Sorin, Hotez, Peter J., Hoy, Damian G., Hsairi, Mohamed, Htet, Aung Soe, Hu, Guoqing, Huang, Hsiang, Huang, John J., Iburg, Kim Moesgaard, Igumbor, Ehimario Uche, Ileanu, Bogdan Vasile, Inoue, Manami, Irenso, Asnake Ararsa, Irvine, Caleb M.S., Islam, Nazrul, Jacobsen, Kathryn H., Jaenisch, Thoma, Jahanmehr, Nader, Jakovljevic, Mihajlo B., Javanbakht, Mehdi, Jayatilleke, Achala Upendra, Jeemon, Panniyammakal, Jensen, Paul N., Jha, Vivekanand, Jin, Ye, John, Denny, John, Oommen, Johnson, Sarah Charlotte, Jonas, Jost B., Jürisson, Mikk, Kabir, Zubair, Kadel, Rajendra, Kahsay, Amaha, Kalkonde, Yogeshwar, Kamal, Ritul, Kan, Haidong, Karch, André, Karema, Corine Kakizi, Karimi, Seyed M., Karthikeyan, Ganesan, Kasaeian, Amir, Kassaw, Nigussie Assefa, Kassebaum, Nicholas J., Kastor, Anshul, Katikireddi, Srinivasa Vittal, Kaul, Anil, Kawakami, Norito, Kazanjan, Konstantin, Keiyoro, Peter Njenga, Kelbore, Sefonias Getachew, Kemp, Andrew Haddon, Kengne, Andre Pascal, Keren, Andre, Kereselidze, Maia, Kesavachandran, Chandrasekharan Nair, Ketema, Ezra Belay, Khader, Yousef Saleh, Khalil, Ibrahim A., Khan, Ejaz Ahmad, Khan, Gulfaraz, Khang, Young-Ho, Khera, Sahil, Khoja, Abdullah Tawfih Abdullah, Khosravi, Mohammad Hossein, Kibret, Getiye Dejenu, Kieling, Christian, Kim, Cho-Il, Kim, Daniel, Kim, Pauline, Kim, Sungroul, Kim, Yun Jin, Kimokoti, Ruth W., Kinfu, Yohanne, Kishawi, Sami, Kissimova-Skarbek, Katarzyna A., Kissoon, Niranjan, Kivimaki, Mika, Knudsen, Ann Kristin, Kokubo, Yoshihiro, Kopec, Jacek A., Kosen, Soewarta, Koul, Parvaiz A., Koyanagi, Ai, Kravchenko, Michael, Krohn, Kristopher J., Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kuipers, Ernst J., Kulikoff, Xie Rachel, Kulkarni, Veena S., Kumar, G. Anil, Kumar, Pushpendra, Kumsa, Fekede Asefa, Kutz, Michael, Lachat, Carl, Lagat, Abraham K., Lager, Anton Carl Jona, Lal, Dharmesh Kumar, Lalloo, Ratilal, Lambert, Nkurunziza, Lan, Qing, Lansingh, Van C., Larson, Heidi J., Larsson, Ander, Laryea, Dennis Odai, Lavados, Pablo M., Laxmaiah, Avula, Lee, Paul H., Leigh, Jame, Leung, Janni, Leung, Ricky, Levi, Miriam, Li, Yongmei, Liao, Yu, Liben, Misgan Legesse, Lim, Stephen S., Linn, Shai, Lipshultz, Steven E., Liu, Shiwei, Lodha, Rakesh, Logroscino, Giancarlo, Lorch, Scott A., Lorkowski, Stefan, Lotufo, Paulo A., Lozano, Rafael, Lunevicius, Raimunda, Lyons, Ronan A., Ma, Stefan, Macarayan, Erlyn Rachelle King, Machado, Isis Eloah, Mackay, Mark T., Magdy Abd El Razek, Mohammed, Magis-Rodriguez, Carlo, Mahdavi, Mahdi, Majdan, Marek, Majdzadeh, Reza, Majeed, Azeem, Malekzadeh, Reza, Malhotra, Rajesh, Malta, Deborah Carvalho, Mantovani, Lorenzo G., Manyazewal, Tsegahun, Mapoma, Chabila C., Marczak, Laurie B., Marks, Guy B., Martinez-Raga, Jose, Martins-Melo, Francisco Rogerlândio, Massano, João, Maulik, Pallab K., Mayosi, Bongani M., Mazidi, Mohsen, McAlinden, Colm, McGarvey, Stephen Theodore, McGrath, John J., McKee, Martin, Mehata, Suresh, Mehndiratta, Man Mohan, Mehta, Kala M., Meier, Toni, Mekonnen, Tefera Chane, Meles, Kidanu Gebremariam, Memiah, Peter, Memish, Ziad A., Mendoza, Walter, Mengesha, Melkamu Merid, Mengistie, Mubarek Abera, Mengistu, Desalegn Tadese, Menon, Geetha R., Menota, Bereket Gebremichael, Mensah, George A., Meretoja, Atte, Meretoja, Tuomo J., Mezgebe, Haftay Berhane, Micha, Renata, Mikesell, Joseph, Miller, Ted R., Mills, Edward J., Minnig, Shawn, Mirarefin, Mojde, Mirrakhimov, Erkin M., Misganaw, Awoke, Mishra, Shiva Raj, Mohammad, Karzan Abdulmuhsin, Mohammadi, Alireza, Mohammed, Kedir Endri, Mohammed, Shafiu, Mohan, Murali B.V., Mohanty, Sanjay K., Mokdad, Ali H., Molla Assaye, Ashagre, Mollenkopf, Sarah K., Molokhia, Mariam, Monasta, Lorenzo, Montañez Hernandez, Julio Cesar, Montico, Marcella, Mooney, Meghan D., Moore, Ami R., Moradi-Lakeh, Maziar, Moraga, Paula, Morawska, Lidia, Moreno Velasquez, Ilai, Mori, Rintaro, Morrison, Shane D., Mruts, Kalayu Birhane, Mueller, Ulrich O., Mullany, Erin, Muller, Kate, Murthy, Gudlavalleti Venkata Satyanarayana, Murthy, Sriniva, Musa, Kamarul Imran, Nachega, Jean B., Nagata, Chie, Nagel, Gabriele, Naghavi, Mohsen, Naidoo, Kovin S., Nanda, Lipika, Nangia, Vinay, Nascimento, Bruno Ramo, Natarajan, Gopalakrishnan, Negoi, Ionut, Nguyen, Cuong Tat, Nguyen, Grant, Nguyen, Quyen Le, Nguyen, Trang Huyen, Ningrum, Dina Nur Anggraini, Nisar, Muhammad Imran, Nomura, Marika, Nong, Vuong Minh, Norheim, Ole F., Norrving, Bo, Noubiap, Jean Jacques N., Nyakarahuka, Luke, Obermeyer, Carla Makhlouf, O'Donnell, Martin J., Ogbo, Felix Akpojene, Oh, In-Hwan, Okoro, Anselm, Oladimeji, Olanrewaju, Olagunju, Andrew Toyin, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Oren, Eyal, Ortiz, Alberto, Osgood-Zimmerman, Aaron, Ota, Erika, Owolabi, Mayowa O., Oyekale, Abayomi Samuel, Mahesh, P.A., Pacella, Rosana E., Pakhale, Smita, Pana, Adrian, Panda, Basant Kumar, Panda-Jonas, Songhomitra, Park, Eun-Kee, Parsaeian, Mahboubeh, Patel, Teja, Patten, Scott B., Patton, George C., Paudel, Deepak, Pereira, David M., Perez-Padilla, Rogelio, Perez-Ruiz, Fernando, Perico, Norberto, Pervaiz, Aslam, Pesudovs, Konrad, Peterson, Carrie Beth, Petri, William Arthur, Petzold, Max, Phillips, Michael Robert, Piel, Frédéric B., Pigott, David M., Pishgar, Farhad, Plass, Dietrich, Polinder, Suzanne, Popova, Svetlana, Postma, Maarten J., Poulton, Richie G., Pourmalek, Farshad, Prasad, Narayan, Purwar, Manorama, Qorbani, Mostafa, Rabiee, Rynaz H.S., Radfar, Amir, Rafay, Anwar, Rahimi-Movaghar, Afarin, Rahimi-Movaghar, Vafa, Rahman, Mahfuzar, Rahman, Mohammad Hifz Ur, Rahman, Sajjad Ur, Rai, Rajesh Kumar, Rajsic, Sasa, Ram, Usha, Rana, Saleem M., Ranabhat, Chhabi Lal, Rao, Paturi Vishnupriya, Rawaf, Salman, Ray, Sarah E., Rego, Maria Albertina Santiago, Rehm, Jürgen, Reiner, Robert C., Remuzzi, Giuseppe, Renzaho, Andre M.N.N., Resnikoff, Serge, Rezaei, Satar, Rezai, Mohammad Sadegh, Ribeiro, Antonio L., Rokni, Mohammad Bagher, Ronfani, Luca, Roshandel, Gholamreza, Roth, Gregory A., Rothenbacher, Dietrich, Roy, Ambuj, Rubagotti, Enrico, Ruhago, George Mugambage, Saadat, Soheil, Sabde, Yogesh Damodar, Sachdev, Perminder S., Sadat, Nafi, Safdarian, Mahdi, Safi, Sare, Safiri, Saeid, Sagar, Rajesh, Sahathevan, Ramesh, Sahebkar, Amirhossein, Sahraian, Mohammad Ali, Salama, Joseph, Salamati, Payman, Salomon, Joshua A., Salvi, Sundeep Santosh, Samy, Abdallah M., Sanabria, Juan Ramon, Sanchez-Niño, Maria Dolore, Santos, Itamar S., Santric Milicevic, Milena M., Sarmiento-Suarez, Rodrigo, Sartorius, Benn, Satpathy, Maheswar, Sawhney, Monika, Saxena, Sonia, Saylan, Mete I., Schmidt, Maria Inê, Schneider, Ione J.C., Schutte, Aletta E., Schwebel, David C., Schwendicke, Falk, Seedat, Soraya, Seid, Abdulbasit Musa, Sepanlou, Sadaf G., Servan-Mori, Edson E., Shackelford, Katya Anne, Shaheen, Amira, Shahraz, Saeid, Shaikh, Masood Ali, Shamsipour, Mansour, Shamsizadeh, Morteza, Islam, Sheikh Mohammed Shariful, Sharma, Jayendra, Sharma, Rajesh, She, Jun, Shen, Jiabin, Shetty, Balakrishna P., Shi, Peilin, Shibuya, Kenji, Shigematsu, Mika, Shiri, Rahman, Shiue, Ivy, Shrime, Mark G., Sigfusdottir, Inga Dora, Silberberg, Donald H., Silpakit, Nari, Silva, Diego Augusto Santo, Silva, João Pedro, Silveira, Dayane Gabriele Alve, Sindi, Shireen, Singh, Abhishek, Singh, Jasvinder A., Singh, Prashant Kumar, Singh, Virendra, Sinha, Dhirendra Narain, Skiadaresi, Eirini, Sligar, Amber, Smith, David L., Sobaih, Badr H.A., Sobngwi, Eugene, Soneji, Samir, Soriano, Joan B., Sreeramareddy, Chandrashekhar T., Srinivasan, Vinay, Stathopoulou, Vasiliki, Steel, Nichola, Stein, Dan J., Steiner, Caitlyn, Stöckl, Heidi, Stokes, Mark Andrew, Strong, Mark, Sufiyan, Muawiyyah Babale, Suliankatchi, Rizwan Abdulkader, Sunguya, Bruno F., Sur, Patrick J., Swaminathan, Soumya, Sykes, Bryan L., Szoeke, Cassandra E.I., Tabarés-Seisdedos, Rafael, Tadakamadla, Santosh Kumar, Tadese, Fentaw, Tandon, Nikhil, Tanne, David, Tarajia, Musharaf, Tavakkoli, Mohammad, Taveira, Nuno, Tehrani-Banihashemi, Arash, Tekelab, Tesfalidet, Tekle, Dejen Yemane, Temam Shifa, Girma, Temsah, Mohamad-Hani, Terkawi, Abdullah Sulieman, Tesema, Cheru Leshargie, Tesssema, Belay, Theis, Andrew, Thomas, Nihal, Thompson, Alex H., Thomson, Alan J., Thrift, Amanda G., Tiruye, Tenaw Yimer, Tobe-Gai, Ruoyan, Tonelli, Marcello, Topor-Madry, Roman, Topouzis, Foti, Tortajada, Miguel, Tran, Bach Xuan, Truelsen, Thoma, Trujillo, Ulise, Tsilimparis, Nikolao, Tuem, Kald Beshir, Tuzcu, Emin Murat, Tyrovolas, Stefano, Ukwaja, Kingsley Nnanna, Undurraga, Eduardo A., Uthman, Olalekan A., Uzochukwu, Benjamin S. Chudi, Van Boven, Job F.M., Varakin, Yuri Y., Varughese, Santosh, Vasankari, Tommi, Vasconcelos, Ana Maria Nogale, Venketasubramanian, Narayanaswamy, Vidavalur, Ramesh, Violante, Francesco S., Vishnu, Abhishek, Vladimirov, Sergey K., Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Vos, Theo, Waid, Jillian L., Wakayo, Tolassa, Wang, Yuan-Pang, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G., Werdecker, Andrea, Wesana, Joshua, Wijeratne, Tissa, Wilkinson, James D., Wiysonge, Charles Shey, Woldeyes, Belete Getahun, Wolfe, Charles D.A., Workicho, Abdulhalik, Workie, Shimelash Bitew, Xavier, Deni, Xu, Gelin, Yaghoubi, Mohsen, Yakob, Bereket, Yalew, Ayalnesh Zemene, Yan, Lijing L., Yano, Yuichiro, Yaseri, Mehdi, Ye, Pengpeng, Yimam, Hassen Hamid, Yip, Paul, Yirsaw, Biruck Desalegn, Yonemoto, Naohiro, Yoon, Seok-Jun, Yotebieng, Marcel, Younis, Mustafa Z., Zaidi, Zoubida, El Sayed Zaki, Maysaa, Zeeb, Hajo, Zenebe, Zerihun Menlkalew, Zerfu, Taddese Alemu, Zhang, Anthony Lin, Zhang, Xueying, Zodpey, Sanjay, Zuhlke, Liesl Joanna, Lopez, Alan D., Murray, Christopher J.L., Wang, H, Abajobir, A, Abate, K, Abbafati, C, Abbas, K, Abd-Allah, F, Abera, S, Abraha, H, Abu-Raddad, L, Abu-Rmeileh, N, Adedeji, I, Adedoyin, R, Adetifa, I, Adetokunboh, O, Afshin, A, Aggarwal, R, Agrawal, A, Agrawal, S, Ahmad Kiadaliri, A, Ahmed, M, Aichour, A, Aichour, I, Aichour, M, Aiyar, S, Akanda, A, Akinyemiju, T, Akseer, N, Al-Eyadhy, A, Al Lami, F, Alabed, S, Alahdab, F, Al-Aly, Z, Alam, K, Alam, N, Alasfoor, D, Aldridge, R, Alene, K, Alhabib, S, Ali, R, Alizadeh-Navaei, R, Aljunid, S, Alkaabi, J, Alkerwi, A, Alla, F, Allam, S, Allebeck, P, Al-Raddadi, R, Alsharif, U, Altirkawi, K, Martin, E, Alvis-Guzman, N, Amare, A, Ameh, E, Amini, E, Ammar, W, Amoako, Y, Anber, N, Andrei, C, Androudi, S, Ansari, H, Ansha, M, Antonio, C, Anwari, P, Ärnlöv, J, Arora, M, Artaman, A, Aryal, K, Asayesh, H, Asgedom, S, Asghar, R, Assadi, R, Atey, T, Atre, S, Avila-Burgos, L, Avokpaho, E, Awasthi, A, Ayala Quintanilla, B, Babalola, T, Bacha, U, Badawi, A, Balakrishnan, K, Balalla, S, Barac, A, Barber, R, Barboza, M, Barker-Collo, S, Bärnighausen, T, Barquera, S, Barregard, L, Barrero, L, Baune, B, Bazargan-Hejazi, S, Bedi, N, Beghi, E, Béjot, Y, Bekele, B, Bell, M, Bello, A, Bennett, D, Bennett, J, Bensenor, I, Benson, J, Berhane, A, Berhe, D, Bernabé, E, Beuran, M, Beyene, A, Bhala, N, Bhansali, A, Bhaumik, S, Bhutta, Z, Bikbov, B, Birungi, C, Biryukov, S, Bisanzio, D, Bizuayehu, H, Bjerregaard, P, Blosser, C, Boneya, D, Boufous, S, Bourne, R, Brazinova, A, Breitborde, N, Brenner, H, Brugha, T, Bukhman, G, Bulto, L, Bumgarner, B, Burch, M, Butt, Z, Cahill, L, Cahuana-Hurtado, L, Campos-Nonato, I, Car, J, Car, M, Cárdenas, R, Carpenter, D, Carrero, J, Carter, A, Castañeda-Orjuela, C, Castillo Rivas, J, Castro, F, Castro, R, Catalá-López, F, Chen, H, Chiang, P, Chibalabala, M, Chisumpa, V, Chitheer, A, Choi, J, Christensen, H, Christopher, D, Ciobanu, L, Cirillo, M, Cohen, A, Colquhoun, S, Coresh, J, Criqui, M, Cromwell, E, Crump, J, Dandona, L, Dandona, R, Dargan, P, Das Neves, J, Davey, G, Davitoiu, D, Davletov, K, De Courten, B, De Leo, D, Degenhardt, L, Deiparine, S, Dellavalle, R, Deribe, K, Deribew, A, Des Jarlais, D, Dey, S, Dharmaratne, S, Dherani, M, Diaz-Torné, C, Ding, E, Dixit, P, Djalalinia, S, Do, H, Doku, D, Donnelly, C, Dos Santos, K, Douwes-Schultz, D, Driscoll, T, Duan, L, Dubey, M, Duncan, B, Dwivedi, L, Ebrahimi, H, El Bcheraoui, C, Ellingsen, C, Enayati, A, Endries, A, Ermakov, S, Eshetie, S, Eshrati, B, Eskandarieh, S, Esteghamati, A, Estep, K, Fanuel, F, Faro, A, Farvid, M, Farzadfar, F, Feigin, V, Fereshtehnejad, S, Fernandes, J, Feyissa, T, Filip, I, Fischer, F, Foigt, N, Foreman, K, Frank, T, Franklin, R, Fraser, M, Friedman, J, Frostad, J, Fullman, N, Fürst, T, Furtado, J, Futran, N, Gakidou, E, Gambashidze, K, Gamkrelidze, A, Gankpé, F, Garcia-Basteiro, A, Gebregergs, G, Gebrehiwot, T, Gebrekidan, K, Gebremichael, M, Gelaye, A, Geleijnse, J, Gemechu, B, Gemechu, K, Genova-Maleras, R, Gesesew, H, Gething, P, Gibney, K, Gill, P, Gillum, R, Giref, A, Girma, B, Giussani, G, Goenka, S, Gomez, B, Gona, P, Gopalani, S, Goulart, A, Graetz, N, Gugnani, H, Gupta, P, Gupta, R, Gupta, T, Gupta, V, Haagsma, J, Hafezi-Nejad, N, Haghparast Bidgoli, H, Hakuzimana, A, Halasa, Y, Hamadeh, R, Hambisa, M, Hamidi, S, Hammami, M, Hancock, J, Handal, A, Hankey, G, Hao, Y, Harb, H, Hareri, H, Harikrishnan, S, Haro, J, Hassanvand, M, Havmoeller, R, Hay, R, Hay, S, He, F, Heredia-Pi, I, Herteliu, C, Hilawe, E, Hoek, H, Horita, N, Hosgood, H, Hostiuc, S, Hotez, P, Hoy, D, Hsairi, M, Htet, A, Hu, G, Huang, H, Huang, J, Iburg, K, Igumbor, E, Ileanu, B, Inoue, M, Irenso, A, Irvine, C, Islam, N, Jacobsen, K, Jaenisch, T, Jahanmehr, N, Jakovljevic, M, Javanbakht, M, Jayatilleke, A, Jeemon, P, Jensen, P, Jha, V, Jin, Y, John, D, John, O, Johnson, S, Jonas, J, Jürisson, M, Kabir, Z, Kadel, R, Kahsay, A, Kalkonde, Y, Kamal, R, Kan, H, Karch, A, Karema, C, Karimi, S, Karthikeyan, G, Kasaeian, A, Kassaw, N, Kassebaum, N, Kastor, A, Katikireddi, S, Kaul, A, Kawakami, N, Kazanjan, K, Keiyoro, P, Kelbore, S, Kemp, A, Kengne, A, Keren, A, Kereselidze, M, Kesavachandran, C, Ketema, E, Khader, Y, Khalil, I, Khan, E, Khan, G, Khang, Y, Khera, S, Khoja, A, Khosravi, M, Kibret, G, Kieling, C, Kim, C, Kim, D, Kim, P, Kim, S, Kim, Y, Kimokoti, R, Kinfu, Y, Kishawi, S, Kissimova-Skarbek, K, Kissoon, N, Kivimaki, M, Knudsen, A, Kokubo, Y, Kopec, J, Kosen, S, Koul, P, Koyanagi, A, Kravchenko, M, Krohn, K, Kuate Defo, B, Kucuk Bicer, B, Kuipers, E, Kulikoff, X, Kulkarni, V, Kumar, G, Kumar, P, Kumsa, F, Kutz, M, Lachat, C, Lagat, A, Lager, A, Lal, D, Lalloo, R, Lambert, N, Lan, Q, Van Lansingh, C, Larson, H, Larsson, A, Laryea, D, Lavados, P, Laxmaiah, A, Lee, P, Leigh, J, Leung, J, Leung, R, Levi, M, Li, Y, Liao, Y, Liben, M, Lim, S, Linn, S, Lipshultz, S, Liu, S, Lodha, R, Logroscino, G, Lorch, S, Lorkowski, S, Lotufo, P, Lozano, R, Lunevicius, R, Lyons, R, Ma, S, Macarayan, E, Machado, I, Mackay, M, Magdy Abd El Razek, M, Magis-Rodriguez, C, Mahdavi, M, Majdan, M, Majdzadeh, R, Majeed, A, Malekzadeh, R, Malhotra, R, Malta, D, Mantovani, L, Manyazewal, T, Mapoma, C, Marczak, L, Marks, G, Martinez-Raga, J, Martins-Melo, F, Massano, J, Maulik, P, Mayosi, B, Mazidi, M, Mcalinden, C, Mcgarvey, S, Mcgrath, J, Mckee, M, Mehata, S, Mehndiratta, M, Mehta, K, Meier, T, Mekonnen, T, Meles, K, Memiah, P, Memish, Z, Mendoza, W, Mengesha, M, Mengistie, M, Mengistu, D, Menon, G, Menota, B, Mensah, G, Meretoja, A, Meretoja, T, Mezgebe, H, Micha, R, Mikesell, J, Miller, T, Mills, E, Minnig, S, Mirarefin, M, Mirrakhimov, E, Misganaw, A, Mishra, S, Mohammad, K, Mohammadi, A, Mohammed, K, Mohammed, S, Mohan, M, Mohanty, S, Mokdad, A, Molla Assaye, A, Mollenkopf, S, Molokhia, M, Monasta, L, Montañez Hernandez, J, Montico, M, Mooney, M, Moore, A, Moradi-Lakeh, M, Moraga, P, Morawska, L, Moreno Velasquez, I, Mori, R, Morrison, S, Mruts, K, Mueller, U, Mullany, E, Muller, K, Murthy, G, Murthy, S, Musa, K, Nachega, J, Nagata, C, Nagel, G, Naghavi, M, Naidoo, K, Nanda, L, Nangia, V, Nascimento, B, Natarajan, G, Negoi, I, Nguyen, C, Nguyen, G, Nguyen, Q, Nguyen, T, Ningrum, D, Nisar, M, Nomura, M, Nong, V, Norheim, O, Norrving, B, Noubiap, J, Nyakarahuka, L, Obermeyer, C, O'Donnell, M, Ogbo, F, Oh, I, Okoro, A, Oladimeji, O, Olagunju, A, Olusanya, B, Olusanya, J, Oren, E, Ortiz, A, Osgood-Zimmerman, A, Ota, E, Owolabi, M, Oyekale, A, Mahesh, P, Pacella, R, Pakhale, S, Pana, A, Panda, B, Panda-Jonas, S, Park, E, Parsaeian, M, Patel, T, Patten, S, Patton, G, Paudel, D, Pereira, D, Perez-Padilla, R, Perez-Ruiz, F, Perico, N, Pervaiz, A, Pesudovs, K, Peterson, C, Petri, W, Petzold, M, Phillips, M, Piel, F, Pigott, D, Pishgar, F, Plass, D, Polinder, S, Popova, S, Postma, M, Poulton, R, Pourmalek, F, Prasad, N, Purwar, M, Qorbani, M, Rabiee, R, Radfar, A, Rafay, A, Rahimi-Movaghar, A, Rahimi-Movaghar, V, Rahman, M, Rahman, S, Rai, R, Rajsic, S, Ram, U, Rana, S, Ranabhat, C, Rao, P, Rawaf, S, Ray, S, Rego, M, Rehm, J, Reiner, R, Remuzzi, G, Renzaho, A, Resnikoff, S, Rezaei, S, Rezai, M, Ribeiro, A, Rokni, M, Ronfani, L, Roshandel, G, Roth, G, Rothenbacher, D, Roy, A, Rubagotti, E, Ruhago, G, Saadat, S, Sabde, Y, Sachdev, P, Sadat, N, Safdarian, M, Safi, S, Safiri, S, Sagar, R, Sahathevan, R, Sahebkar, A, Sahraian, M, Salama, J, Salamati, P, Salomon, J, Salvi, S, Samy, A, Sanabria, J, Sanchez-Niño, M, Santos, I, Santric Milicevic, M, Sarmiento-Suarez, R, Sartorius, B, Satpathy, M, Sawhney, M, Saxena, S, Saylan, M, Schmidt, M, Schneider, I, Schutte, A, Schwebel, D, Schwendicke, F, Seedat, S, Seid, A, Sepanlou, S, Servan-Mori, E, Shackelford, K, Shaheen, A, Shahraz, S, Shaikh, M, Shamsipour, M, Shamsizadeh, M, Islam, S, Sharma, J, Sharma, R, She, J, Shen, J, Shetty, B, Shi, P, Shibuya, K, Shigematsu, M, Shiri, R, Shiue, I, Shrime, M, Sigfusdottir, I, Silberberg, D, Silpakit, N, Silva, D, Silva, J, Silveira, D, Sindi, S, Singh, A, Singh, J, Singh, P, Singh, V, Sinha, D, Skiadaresi, E, Sligar, A, Smith, D, Sobaih, B, Sobngwi, E, Soneji, S, Soriano, J, Sreeramareddy, C, Srinivasan, V, Stathopoulou, V, Steel, N, Stein, D, Steiner, C, Stöckl, H, Stokes, M, Strong, M, Sufiyan, M, Suliankatchi, R, Sunguya, B, Sur, P, Swaminathan, S, Sykes, B, Szoeke, C, Tabarés-Seisdedos, R, Tadakamadla, S, Tadese, F, Tandon, N, Tanne, D, Tarajia, M, Tavakkoli, M, Taveira, N, Tehrani-Banihashemi, A, Tekelab, T, Tekle, D, Temam Shifa, G, Temsah, M, Terkawi, A, Tesema, C, Tesssema, B, Theis, A, Thomas, N, Thompson, A, Thomson, A, Thrift, A, Tiruye, T, Tobe-Gai, R, Tonelli, M, Topor-Madry, R, Topouzis, F, Tortajada, M, Tran, B, Truelsen, T, Trujillo, U, Tsilimparis, N, Tuem, K, Tuzcu, E, Tyrovolas, S, Ukwaja, K, Undurraga, E, Uthman, O, Uzochukwu, B, Van Boven, J, Varakin, Y, Varughese, S, Vasankari, T, Vasconcelos, A, Venketasubramanian, N, Vidavalur, R, Violante, F, Vishnu, A, Vladimirov, S, Vlassov, V, Vollset, S, Vos, T, Waid, J, Wakayo, T, Wang, Y, Weichenthal, S, Weiderpass, E, Weintraub, R, Werdecker, A, Wesana, J, Wijeratne, T, Wilkinson, J, Wiysonge, C, Woldeyes, B, Wolfe, C, Workicho, A, Workie, S, Xavier, D, Xu, G, Yaghoubi, M, Yakob, B, Yalew, A, Yan, L, Yano, Y, Yaseri, M, Ye, P, Yimam, H, Yip, P, Yirsaw, B, Yonemoto, N, Yoon, S, Yotebieng, M, Younis, M, Zaidi, Z, El Sayed Zaki, M, Zeeb, H, Zenebe, Z, Zerfu, T, Zhang, A, Zhang, X, Zodpey, S, Zuhlke, L, Lopez, A, Murray, C, Erasmus MC other, Emergency Medicine, Rehabilitation Medicine, Gastroenterology & Hepatology, Public Health, and Neurology
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Dánarmein ,Heilsufar ,Dánartíðni ,Lífslíkur ,Epidemiology ,Aldurshópar ,ALCOHOL ,Börn ,Medicine and Health Sciences ,Psychology ,DEVELOPING-COUNTRIES ,Children ,Konur ,Ungbörn ,Tölfræði ,Educational status ,Aldraðir ,Medicine (all) ,Global burden of disease/statistics and numerical data ,DEATH ,Men ,Þjóðir ,Staðtölur ,Stillbirth ,Sálfræði ,World health ,SURVIVAL ,Income ,CHILD-MORTALITY ,HEALTH ,Burðarmálsdauði ,Infants ,Age distribution ,HIV infections ,Child mortality ,Alnæmi ,Menntun ,GBD ,Fæðingartíðni ,RUSSIAN MORTALITY ,Birth rate ,Life Expectancy ,SDG 3 - Good Health and Well-being ,Women ,Mortality ,METAANALYSIS ,Faraldsfræði ,HIV ,Frjósemi ,Fertility ,Socioeconomic Factors ,Karlar ,Barnadauði ,Félagshagfræði ,Tekjur ,Older people ,Cause of death/trends ,RA - Abstract
Correction in: Group Author(s): GBD 2016 Mortality Collaborators LANCET Volume: 390 Issue: 10106 Pages: E38-E38 Published: OCT 28 2017, Background Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respect to development status can identify exemplars for best practice. To accomplish this, the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) estimated age-specific and sex-specific all-cause mortality between 1970 and 2016 for 195 countries and territories and at the subnational level for the five countries with a population greater than 200 million in 2016. Methods We have evaluated how well civil registration systems captured deaths using a set of demographic methods called death distribution methods for adults and from consideration of survey and census data for children younger than 5 years. We generated an overall assessment of completeness of registration of deaths by dividing registered deaths in each location-year by our estimate of all-age deaths generated from our overall estimation process. For 163 locations, including subnational units in countries with a population greater than 200 million with complete vital registration (VR) systems, our estimates were largely driven by the observed data, with corrections for small fluctuations in numbers and estimation for recent years where there were lags in data reporting (lags were variable by location, generally between 1 year and 6 years). For other locations, we took advantage of different data sources available to measure under-5 mortality rates (U5MR) using complete birth histories, summary birth histories, and incomplete VR with adjustments; we measured adult mortality rate (the probability of death in individuals aged 15-60 years) using adjusted incomplete VR, sibling histories, and household death recall. We used the U5MR and adult mortality rate, together with crude death rate due to HIV in the GBD model life table system, to estimate age-specific and sex-specific death rates for each location-year. Using various international databases, we identified fatal discontinuities, which we defined as increases in the death rate of more than one death per million, resulting from conflict and terrorism, natural disasters, major transport or technological accidents, and a subset of epidemic infectious diseases; these were added to estimates in the relevant years. In 47 countries with an identified peak adult prevalence for HIV/AIDS of more than 0.5% and where VR systems were less than 65% complete, we informed our estimates of age-sex-specific mortality using the Estimation and Projection Package (EPP)-Spectrum model fitted to national HIV/AIDS prevalence surveys and antenatal clinic serosurveillance systems. We estimated stillbirths, early neonatal, late neonatal, and childhood mortality using both survey and VR data in spatiotemporal Gaussian process regression models. We estimated abridged life tables for all location-years using age-specific death rates. We grouped locations into development quintiles based on the Sociodemographic Index (SDI) and analysed mortality trends by quintile. Using spline regression, we estimated the expected mortality rate for each age-sex group as a function of SDI. We identified countries with higher life expectancy than expected by comparing observed life expectancy to anticipated life expectancy on the basis of development status alone. Findings Completeness in the registration of deaths increased from 28% in 1970 to a peak of 45% in 2013; completeness was lower after 2013 because of lags in reporting. Total deaths in children younger than 5 years decreased from 1970 to 2016, and slower decreases occurred at ages 5-24 years. By contrast, numbers of adult deaths increased in each 5-year age bracket above the age of 25 years. The distribution of annualised rates of change in age-specific mortality rate differed over the period 2000 to 2016 compared with earlier decades: increasing annualised rates of change were less frequent, although rising annualised rates of change still occurred in some locations, particularly for adolescent and younger adult age groups. Rates of stillbirths and under-5 mortality both decreased globally from 1970. Evidence for global convergence of death rates was mixed; although the absolute difference between age-standardised death rates narrowed between countries at the lowest and highest levels of SDI, the ratio of these death rates-a measure of relative inequality-increased slightly. There was a strong shift between 1970 and 2016 toward higher life expectancy, most noticeably at higher levels of SDI. Among countries with populations greater than 1 million in 2016, life expectancy at birth was highest for women in Japan, at 86.9 years (95% UI 86.7-87.2), and for men in Singapore, at 81.3 years (78.8-83.7) in 2016. Male life expectancy was generally lower than female life expectancy between 1970 and 2016, and the gap between male and female life expectancy increased with progression to higher levels of SDI. Some countries with exceptional health performance in 1990 in terms of the difference in observed to expected life expectancy at birth had slower progress on the same measure in 2016. Interpretation Globally, mortality rates have decreased across all age groups over the past five decades, with the largest improvements occurring among children younger than 5 years. However, at the national level, considerable heterogeneity remains in terms of both level and rate of changes in age-specific mortality; increases in mortality for certain age groups occurred in some locations. We found evidence that the absolute gap between countries in age-specific death rates has declined, although the relative gap for some age-sex groups increased. Countries that now lead in terms of having higher observed life expectancy than that expected on the basis of development alone, or locations that have either increased this advantage or rapidly decreased the deficit from expected levels, could provide insight into the means to accelerate progress in nations where progress has stalled., Bill & Melinda Gates Foundation, and the National Institute on Aging and the National Institute of Mental Health of the National Institutes of Health.
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33. Persistent pulmonary hypertension of the newborn in donor twin: another complication of fetal anemia in twin to twin transfusion syndrome?
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Vidavalur, Ramesh, Praveen, Vijayakumar, and Folaranmi, Oluwamayowale
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Fetal diseases -- Risk factors ,Fetal diseases -- Diagnosis ,Fetal diseases -- Care and treatment ,Fetal diseases -- Case studies ,Fetofetal transfusion -- Health aspects ,Pulmonary hypertension -- Diagnosis ,Pulmonary hypertension -- Care and treatment ,Pulmonary hypertension -- Case studies ,Health - Abstract
Table of Contents Abstract Introduction Case Report Discussion References Abstract Twin to twin transfusion syndrome (TTTS) is a major complication of monochorionic multiple gestation associated with significant perinatal morbidity and [...]
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- 2008
34. City initiative: baby steps to a better future
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Vidavalur, Ramesh
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The article on the new initiative for newborn health in India by A. Fernandez and D. Osrin [1] outlines an innovative approach to tackling the alarming global burden of infant [...]
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- 2006
35. Sildenafil augments early protective transcriptional changes after ischemia in mouse myocardium
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Vidavalur, Ramesh, primary, Penumathsa, Suresh Varma, additional, Thirunavukkarasu, Mahesh, additional, Zhan, Lijun, additional, Krueger, Winfried, additional, and Maulik, Nilanjana, additional
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- 2009
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36. Ex Vivo and In Vivo Approaches to Study Mechanisms of Cardioprotection Targeting Ischemia/Reperfusion (I/R) Injury: Useful Techniques for Cardiovascular Drug Discovery
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Vidavalur, Ramesh, primary, Swarnakar, Snehasikta, additional, Thirunavukkarasu, Mahesh, additional, Samuel, Samson, additional, and Maulik, Nilanjana, additional
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- 2008
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37. Sildenafil induces angiogenic response in human coronary arteriolar endothelial cells through the expression of thioredoxin, hemeoxygenase and vascular endothelial growth factor
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Vidavalur, Ramesh, primary, Penumathsa, Suresh Varma, additional, Zhan, Lijun, additional, Thirunavukkarasu, Mahesh, additional, and Maulik, Nilanjana, additional
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- 2006
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38. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
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Hay, Simon I, Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbas, Kaja M, Abd-Allah, Foad, Abdulkader, Rizwan Suliankatchi, Abdulle, Abdishakur M, Abebo, Teshome Abuka, Abera, Semaw Ferede, Aboyans, Victor, Abu-Raddad, Laith J, Ackerman, Ilana N, Adedeji, Isaac A, Adetokunboh, Olatunji, Afshin, Ashkan, Aggarwal, Rakesh, Agrawal, Sutapa, Agrawal, Anurag, Ahmed, Muktar Beshir, Aichour, Miloud Taki Eddine, Aichour, Amani Nidhal, Aichour, Ibtihel, Aiyar, Sneha, Akinyemiju, Tomi F, Akseer, Nadia, Al Lami, Faris Hasan, Alahdab, Fares, Al-Aly, Ziyad, Alam, Khurshid, Alam, Noore, Alam, Tahiya, Alasfoor, Deena, Alene, Kefyalew Addis, Ali, Raghib, Alizadeh-Navaei, Reza, Alkaabi, Juma M, Alkerwi, Ala'a, Alla, François, Allebeck, Peter, Allen, Christine, Al-Maskari, Fatma, AlMazroa, Mohammad AbdulAziz, Al-Raddadi, Rajaa, Alsharif, Ubai, Alsowaidi, Shirina, Althouse, Benjamin M, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amini, Erfan, Ammar, Walid, Amoako, Yaw Ampem, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Anwari, Palwasha, Ärnlöv, Johan, Arora, Megha, Artaman, Al, Aryal, Krishna Kumar, Asgedom, Solomon W, Atey, Tesfay Mehari, Atnafu, Niguse Tadele, Avila-Burgos, Leticia, Avokpaho, Euripide Frinel G Arthur, Awasthi, Ashish, Awasthi, Shally, Azarpazhooh, Mahmoud Reza, Azzopardi, Peter, Babalola, Tesleem Kayode, Bacha, Umar, Badawi, Alaa, Balakrishnan, Kalpana, Bannick, Marlena S, Barac, Aleksandra, Barker-Collo, Suzanne L, Bärnighausen, Till, Barquera, Simon, Barrero, Lope H, Basu, Sanjay, Battista, Robert, Battle, Katherine E, Baune, Bernhard T, Bazargan-Hejazi, Shahrzad, Beardsley, Justin, Bedi, Neeraj, Béjot, Yannick, Bekele, Bayu Begashaw, Bell, Michelle L, Bennett, Derrick A, Bennett, James R, Bensenor, Isabela M, Benson, Jennifer, Berhane, Adugnaw, Berhe, Derbew Fikadu, Bernabé, Eduardo, Betsu, Balem Demtsu, Beuran, Mircea, Beyene, Addisu Shunu, Bhansali, Anil, Bhatt, Samir, Bhutta, Zulfiqar A, Biadgilign, Sibhatu, Bicer, Burcu Kucuk, Bienhoff, Kelly, Bikbov, Boris, Birungi, Charles, Biryukov, Stan, Bisanzio, Donal, Bizuayehu, Habtamu Mellie, Blyth, Fiona M, Boneya, Dube Jara, Bose, Dipan, Bou-Orm, Ibrahim R, Bourne, Rupert R A, Brainin, Michael, Brayne, Carol, Brazinova, Alexandra, Breitborde, Nicholas J K, Briant, Paul S, Britton, Gabrielle, Brugha, Traolach S, Buchbinder, Rachelle, Bulto, Lemma Negesa Bulto, Bumgarner, Blair R, Butt, Zahid A, Cahuana-Hurtado, Lucero, Cameron, Ewan, Campos-Nonato, Ismael Ricardo, Carabin, Hélène, Cárdenas, Rosario, Carpenter, David O, Carrero, Juan Jesus, Carter, Austin, Carvalho, Felix, Casey, Daniel, Castañeda-Orjuela, Carlos A, Castle, Chris D, Catalá-López, Ferrán, Chang, Jung-Chen, Charlson, Fiona J, Chaturvedi, Pankaj, Chen, Honglei, Chibalabala, Mirriam, Chibueze, Chioma Ezinne, Chisumpa, Vesper Hichilombwe, Chitheer, Abdulaal A, Chowdhury, Rajiv, Christopher, Devasahayam Jesudas, Ciobanu, Liliana G, Cirillo, Massimo, Colombara, Danny, Cooper, Leslie Trumbull, Cooper, Cyrus, Cortesi, Paolo Angelo, Cortinovis, Monica, Criqui, Michael H, Cromwell, Elizabeth A, Cross, Marita, Crump, John A, Dadi, Abel Fekadu, Dalal, Koustuv, Damasceno, Albertino, Dandona, Lalit, Dandona, Rakhi, das Neves, José, Davitoiu, Dragos V, Davletov, Kairat, de Courten, Barbora, De Leo, Diego, De Steur, Hans, Defo, Barthelemy Kuate, Degenhardt, Louisa, Deiparine, Selina, Dellavalle, Robert P, Deribe, Kebede, Deribew, Amare, Des Jarlais, Don C, Dey, Subhojit, Dharmaratne, Samath D, Dhillon, Preet K, Dicker, Daniel, Djalainia, Shirin, Do, Huyen Phuc, Dokova, Klara, Doku, David Teye, Dorsey, E Ray, dos Santos, Kadine Priscila Bender, Driscoll, Tim R, Dubey, Manisha, Duncan, Bruce Bartholow, Ebel, Beth E, Echko, Michelle, El-Khatib, Ziad Ziad, Enayati, Ahmadali, Endries, Aman Yesuf, Ermakov, Sergey Petrovich, Erskine, Holly E, Eshetie, Setegn, Eshrati, Babak, Esteghamati, Alireza, Estep, Kara, Fanuel, Fanuel Belayneh Bekele, Farag, Tamer, Farinha, Carla Sofia e Sa, Faro, André, Farzadfar, Farshad, Fazeli, Mir Sohail, Feigin, Valery L, Feigl, Andrea B, Fereshtehnejad, Seyed-Mohammad, Fernandes, João C, Ferrari, Alize J, Feyissa, Tesfaye Regassa, Filip, Irina, Fischer, Florian, Fitzmaurice, Christina, Flaxman, Abraham D, Foigt, Nataliya, Foreman, Kyle J, Franklin, Richard C, Frostad, Joseph J, Fullman, Nancy, Fürst, Thomas, Furtado, Joao M, Futran, Neal D, Gakidou, Emmanuela, Garcia-Basteiro, Alberto L, Gebre, Teshome, Gebregergs, Gebremedhin Berhe, Gebrehiwot, Tsegaye Tewelde, Geleijnse, Johanna M, Geleto, Ayele, Gemechu, Bikila Lencha, Gesesew, Hailay Abrha, Gething, Peter W, Ghajar, Alireza, Gibney, Katherine B, Gillum, Richard F, Ginawi, Ibrahim Abdelmageem Mohamed, Gishu, Melkamu Dedefo, Giussani, Giorgia, Godwin, William W, Goel, Kashish, Goenka, Shifalika, Goldberg, Ellen M, Gona, Philimon N, Goodridge, Amador, Gopalani, Sameer Vali, Gosselin, Richard A, Gotay, Carolyn C, Goto, Atsushi, Goulart, Alessandra Carvalho, Graetz, Nicholas, Gugnani, Harish Chander, Gupta, Prakash C, Gupta, Rajeev, Gupta, Tanush, Gupta, Vipin, Gupta, Rahul, Gutiérrez, Reyna A, Hachinski, Vladimir, Hafezi-Nejad, Nima, Hailu, Alemayehu Desalegne, Hailu, Gessessew Bugssa, Hamadeh, Randah Ribhi, Hamidi, Samer, Hammami, Mouhanad, Handal, Alexis J, Hankey, Graeme J, Hao, Yuantao, Harb, Hilda L, Hareri, Habtamu Abera, Haro, Josep Maria, Harun, Kimani M, Harvey, James, Hassanvand, Mohammad Sadegh, Havmoeller, Rasmus, Hay, Roderick J, Hedayati, Mohammad T, Hendrie, Delia, Henry, Nathaniel J, Heredia-Pi, Ileana Beatriz, Heydarpour, Pouria, Hoek, Hans W, Hoffman, Howard J, Horino, Masako, Horita, Nobuyuki, Hosgood, H Dean, Hostiuc, Sorin, Hotez, Peter J, Hoy, Damian G, Htet, Aung Soe, Hu, Guoqing, Huang, John J, Huynh, Chantal, Iburg, Kim Moesgaard, Igumbor, Ehimario Uche, Ikeda, Chad, Irvine, Caleb Mackay Salpeter, Islam, Sheikh Mohammed Shariful, Jacobsen, Kathryn H, Jahanmehr, Nader, Jakovljevic, Mihajlo B, James, Peter, Jassal, Simerjot K, Javanbakht, Mehdi, Jayaraman, Sudha P, Jeemon, Panniyammakal, Jensen, Paul N, Jha, Vivekanand, Jiang, Guohong, John, Denny, Johnson, Catherine O, Johnson, Sarah Charlotte, Jonas, Jost B, Jürisson, Mikk, Kabir, Zubair, Kadel, Rajendra, Kahsay, Amaha, Kamal, Ritul, Kar, Chittaranjan, Karam, Nadim E, Karch, André, Karema, Corine Kakizi, Karimi, Seyed M, Karimkhani, Chante, Kasaeian, Amir, Kassa, Getachew Mullu, Kassaw, Nigussie Assefa, Kassebaum, Nicholas J, Kastor, Anshul, Katikireddi, Srinivasa Vittal, Kaul, Anil, Kawakami, Norito, Keiyoro, Peter Njenga, Kemmer, Laura, Kengne, Andre Pascal, Keren, Andre, Kesavachandran, Chandrasekharan Nair, Khader, Yousef Saleh, Khalil, Ibrahim A, Khan, Ejaz Ahmad, Khang, Young-Ho, Khoja, Abdullah T, Khosravi, Ardeshir, Khubchandani, Jagdish, Kiadaliri, Aliasghar Ahmad, Kieling, Christian, Kim, Yun Jin, Kim, Daniel, Kimokoti, Ruth W, Kinfu, Yohannes, Kisa, Adnan, Kissimova-Skarbek, Katarzyna A, Kissoon, Niranjan, Kivimaki, Mika, Knudsen, Ann Kristin, Kokubo, Yoshihiro, Kolte, Dhaval, Kopec, Jacek A, Kosen, Soewarta, Kotsakis, Georgios A, Koul, Parvaiz A, Koyanagi, Ai, Kravchenko, Michael, Krohn, Kristopher J, Kumar, G Anil, Kumar, Pushpendra, Kyu, Hmwe H, Lager, Anton Carl Jonas, Lal, Dharmesh Kumar, Lalloo, Ratilal, Lallukka, Tea, Lambert, Nkurunziza, Lan, Qing, Lansingh, Van C, Larsson, Anders, Leasher, Janet L, Lee, Paul H, Leigh, James, Leshargie, Cheru Tesema, Leung, Janni, Leung, Ricky, Levi, Miriam, Li, Yichong, Li, Yongmei, Liang, Xiaofeng, Liben, Misgan Legesse, Lim, Stephen S, Linn, Shai, Liu, Patrick Y, Liu, Angela, Liu, Shiwei, Liu, Yang, Lodha, Rakesh, Logroscino, Giancarlo, Looker, Katharine J, Lopez, Alan D, Lorkowski, Stefan, Lotufo, Paulo A, Lozano, Rafael, Lucas, Timothy C D, Lunevicius, Raimundas, Lyons, Ronan A, Macarayan, Erlyn Rachelle King, Maddison, Emilie R, Magdy Abd El Razek, Hassan Magdy Abd, Magdy Abd El Razek, Mohammed, Magis-Rodriguez, Carlos, Mahdavi, Mahdi, Majdan, Marek, Majdzadeh, Reza, Majeed, Azeem, Malekzadeh, Reza, Malhotra, Rajesh, Malta, Deborah Carvalho, Mamun, Abdullah A, Manguerra, Helena, Manhertz, Treh, Mantovani, Lorenzo G, Mapoma, Chabila C, March, Lyn M, Marczak, Laurie B, Martinez-Raga, Jose, Martins, Paulo Henrique Viegas, Martins-Melo, Francisco Rogerlândio, Martopullo, Ira, März, Winfried, Mathur, Manu Raj, Mazidi, Mohsen, McAlinden, Colm, McGaughey, Madeline, McGrath, John J, McKee, Martin, Mehata, Suresh, Meier, Toni, Meles, Kidanu Gebremariam, Memiah, Peter, Memish, Ziad A, Mendoza, Walter, Mengesha, Melkamu Merid, Mengistie, Mubarek Abera, Mengistu, Desalegn Tadese, Mensah, George A, Meretoja, Tuomo J, Meretoja, Atte, Mezgebe, Haftay Berhane, Micha, Renata, Millear, Anoushka, Miller, Ted R, Minnig, Shawn, Mirarefin, Mojde, Mirrakhimov, Erkin M, Misganaw, Awoke, Mishra, Shiva Raj, Mitchell, Philip B, Mohammad, Karzan Abdulmuhsin, Mohammadi, Alireza, Mohammed, Muktar Sano Kedir, Mohammed, Kedir Endris, Mohammed, Shafiu, Mohan, Murali B V, Mokdad, Ali H, Mollenkopf, Sarah K, Monasta, Lorenzo, Montañez Hernandez, Julio Cesar, Montico, Marcella, Moradi-Lakeh, Maziar, Moraga, Paula, Morawska, Lidia, Mori, Rintaro, Morrison, Shane D, Moses, Mark, Mountjoy-Venning, Cliff, Mruts, Kalayu Birhane, Mueller, Ulrich O, Muller, Kate, Murdoch, Michele E, Murthy, Gudlavalleti Venkata Satyanarayana, Murthy, Srinivas, Musa, Kamarul Imran, Nachega, Jean B, Nagel, Gabriele, Naghavi, Mohsen, Naheed, Aliya, Naidoo, Kovin S, Nangia, Vinay, Nasher, Jamal T, Natarajan, Gopalakrishnan, Negasa, Dumessa Edessa, Negoi, Ruxandra Irina, Negoi, Ionut, Newton, Charles R, Ngunjiri, Josephine Wanjiku, Nguyen, Cuong Tat, Nguyen, Quyen Le, Nguyen, Trang Huyen, Nguyen, Grant, Nguyen, Minh, Nichols, Emma, Ningrum, Dina Nur Anggraini, Nong, Vuong Minh, Norheim, Ole F, Norrving, Bo, Noubiap, Jean Jacques N, Nyandwi, Alypio, Obermeyer, Carla Makhlouf, O'Donnell, Martin J, Ogbo, Felix Akpojene, Oh, In-Hwan, Okoro, Anselm, Oladimeji, Olanrewaju, Olagunju, Andrew Toyin, Olagunju, Tinuke Oluwasefunmi, Olsen, Helen E, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Ong, Kanyin, Opio, John Nelson, Oren, Eyal, Ortiz, Alberto, Osborne, Richard H, Osgood-Zimmerman, Aaron, Osman, Majdi, Ota, Erika, Owolabi, Mayowa O, PA, Mahesh, Pacella, Rosana E, Panda, Basant Kumar, Pandian, Jeyaraj Durai, Papachristou, Christina, Park, Eun-Kee, Parry, Charles D, Parsaeian, Mahboubeh, Patil, Snehal T, Patten, Scott B, Patton, George C, Paudel, Deepak, Paulson, Katherine, Pearce, Neil, Pereira, David M, Perez, Krystle Marie, Perico, Norberto, Pesudovs, Konrad, Peterson, Carrie Beth, Petri, William Arthur, Petzold, Max, Phillips, Michael Robert, Phipps, Geoffrey, Pigott, David M, Pillay, Julian David, Pinho, Christine, Piradov, Michael A, Plass, Dietrich, Pletcher, Martin A, Popova, Svetlana, Poulton, Richie G, Pourmalek, Farshad, Prabhakaran, Dorairaj, Prasad, Narayan, Purcell, Carrie, Purwar, Manorama, Qorbani, Mostafa, Quintanilla, Beatriz Paulina Ayala, Rabiee, Rynaz H S, Radfar, Amir, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Afarin, Rahimi-Movaghar, Vafa, Rahman, Mohammad Hifz Ur, Rahman, Muhammad Aziz, Rahman, Mahfuzar, Rai, Rajesh Kumar, Rajsic, Sasa, Ram, Usha, Ranabhat, Chhabi Lal, Rangaswamy, Thara, Rankin, Zane, Rao, Paturi Vishnupriya, Rao, Puja C, Rawaf, Salman, Ray, Sarah E, Reiner, Robert C, Reinig, Nikolas, Reitsma, Marissa, Remuzzi, Giuseppe, Renzaho, Andre M N, Resnikoff, Serge, Rezaei, Satar, Ribeiro, Antonio L, Rivas, Jacqueline Castillo, Roba, Hirbo Shore, Robinson, Stephen R, Rojas-Rueda, David, Rokni, Mohammad Bagher, Ronfani, Luca, Roshandel, Gholamreza, Roth, Gregory A, Rothenbacher, Dietrich, Roy, Ambuj, Rubagotti, Enrico, Ruhago, George Mugambage, Saadat, Soheil, Safdarian, Mahdi, Safiri, Saeid, Sagar, Rajesh, Sahathevan, Ramesh, Sahraian, Mohammad Ali, Salama, Joseph, Saleh, Muhammad Muhammad, Salomon, Joshua A, Salvi, Sundeep Santosh, Samy, Abdallah M, Sanabria, Juan Ramon, Sanchez-Niño, Maria Dolores, Santomauro, Damian, Santos, João Vasco, Santos, Itamar S, Santric Milicevic, Milena M, Sartorius, Benn, Satpathy, Maheswar, Sawhney, Monika, Saxena, Sonia, Schelonka, Kathryn, Schmidt, Maria Inês, Schneider, Ione J C, Schöttker, Ben, Schutte, Aletta E, Schwebel, David C, Schwendicke, Falk, Seedat, Soraya, Sepanlou, Sadaf G, Servan-Mori, Edson E, Shaheen, Amira, Shaikh, Masood Ali, Shamsipour, Mansour, Sharma, Rajesh, Sharma, Jayendra, She, Jun, Shi, Peilin, Shibuya, Kenji, Shields, Chloe, Shifa, Girma Temam, Shiferaw, Mekonnen Sisay, Shigematsu, Mika, Shiri, Rahman, Shirkoohi, Reza, Shirude, Shreya, Shishani, Kawkab, Shoman, Haitham, Siabani, Soraya, Sibai, Abla Mehio, Sigfusdottir, Inga Dora, Silberberg, Donald H, Silva, Diego Augusto Santos, Silva, João Pedro, Silveira, Dayane Gabriele Alves, Singh, Jasvinder A, Singh, Om Prakash, Singh, Narinder Pal, Singh, Virendra, Sinha, Dhirendra Narain, Skiadaresi, Eirini, Slepak, Erica Leigh, Smith, David L, Smith, Mari, Sobaih, Badr H A, Sobngwi, Eugene, Soljak, Michael, Sorensen, Reed J D, Sousa, Tatiane Cristina Moraes, Sposato, Luciano A, Sreeramareddy, Chandrashekhar T, Srinivasan, Vinay, Stanaway, Jeffrey D, Stathopoulou, Vasiliki, Steel, Nicholas, Stein, Dan J, Steiner, Caitlyn, Steinke, Sabine, Stokes, Mark Andrew, Stovner, Lars Jacob, Strub, Bryan, Subart, Michelle, Sufiyan, Muawiyyah Babale, Sunguya, Bruno F, Sur, Patrick J, Swaminathan, Soumya, Sykes, Bryan L, Sylte, Dillon, Szoeke, Cassandra E I, Tabarés-Seisdedos, Rafael, Tadakamadla, Santosh Kumar, Taffere, Getachew Redae, Takala, Jukka S, Tandon, Nikhil, Tanne, David, Tarekegn, Yihunie L, Tavakkoli, Mohammad, Taveira, Nuno, Taylor, Hugh R, Tegegne, Teketo Kassaw, Tehrani-Banihashemi, Arash, Tekelab, Tesfalidet, Terkawi, Abdullah Sulieman, Tesfaye, Dawit Jember, Tesssema, Belay, Thakur, JS, Thamsuwan, Ornwipa, Theadom, Alice M, Theis, Andrew M, Thomas, Katie E, Thomas, Nihal, Thompson, Robert, Thrift, Amanda G, Tobe-Gai, Ruoyan, Tobollik, Myriam, Tonelli, Marcello, Topor-Madry, Roman, Tortajada, Miguel, Touvier, Mathilde, Traebert, Jefferson, Tran, Bach Xuan, Troeger, Christopher, Truelsen, Thomas, Tsoi, Derrick, Tuzcu, Emin Murat, Tymeson, Hayley, Tyrovolas, Stefanos, Ukwaja, Kingsley Nnanna, Undurraga, Eduardo A, Uneke, Chigozie Jesse, Updike, Rachel, Uthman, Olalekan A, Uzochukwu, Benjamin S Chudi, van Boven, Job F M, Varughese, Santosh, Vasankari, Tommi, Veerman, Lennert J, Venkatesh, S, Venketasubramanian, Narayanaswamy, Vidavalur, Ramesh, Vijayakumar, Lakshmi, Violante, Francesco S, Vishnu, Abhishek, Vladimirov, Sergey K, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Vos, Theo, Wadilo, Fiseha, Wakayo, Tolassa, Wallin, Mitchell T, Wang, Yuan-Pang, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Weiss, Daniel J, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A, Wijeratne, Tissa, Williams, Hywel C, Wiysonge, Charles Shey, Woldeyes, Belete Getahun, Wolfe, Charles D A, Woodbrook, Rachel, Woolf, Anthony D, Workicho, Abdulhalik, Xavier, Denis, Xu, Gelin, Yadgir, Simon, Yaghoubi, Mohsen, Yakob, Bereket, Yan, Lijing L, Yano, Yuichiro, Ye, Pengpeng, Yihdego, Mahari Gidey, Yimam, Hassen Hamid, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Yotebieng, Marcel, Younis, Mustafa Z, Yu, Chuanhua, Zaidi, Zoubida, Zaki, Maysaa El Sayed, Zegeye, Elias Asfaw, Zenebe, Zerihun Menlkalew, Zhang, Xueying, Zheng, Yingfeng, Zhou, Maigeng, Zipkin, Ben, Zodpey, Sanjay, Zoeckler, Leo, Zuhlke, Liesl Joanna, and Murray, Christopher J L
- Subjects
1. No poverty ,3. Good health
39. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
- Author
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Salama, Joseph, Miller, Ted R., Touvier, Mathilde, Ali, Raghib, Undurraga, Eduardo A., Owolabi, Mayowa O., März, Winfried, Douwes-Schultz, Dirk, Abate, Kalkidan Hassen, Petzold, Max, Lotufo, Paulo A., Malta, Deborah Carvalho, Terkawi, Abdullah Sulieman, Sagar, Rajesh, Varughese, Santosh, Setegn, Tesfaye, Monasta, Lorenzo, Khosravi, Ardeshir, Naldi, Luigi, Malekzadeh, Reza, Negoi, Ruxandra Irina, Olsen, Helen E., Popova, Svetlana, Kamal, Ritul, Sinha, Dhirendra Narain, Jensen, Paul N., Tehrani-Banihashemi, Arash, Avila-Burgos, Leticia, Servan-Mori, Edson E., Safi, Sare, Zaidi, Zoubida, Panda, Basant Kumar, Mitchell, Philip B., Li, Yichong, Sharma, Rajesh, Estep, Kara, Barregard, Lars, Mendoza, Walter, Zodpey, Sanjay, Saxena, Sonia, Gillum, Richard F., Kieling, Christian, Kucuk Bicer, Burcu, Kengne, Andre Pascal, Topor-Madry, Roman, Steiner, Caitlyn, Mori, Rintaro, Noubiap, Jean Jacques N., Carapetis, Jonathan R., Dalal, Koustuv, Deiparine, Selina, Shiri, Rahman, Nagel, Gabriele, Natarajan, Gopalakrishnan, Mokdad, Ali H., Martins-Melo, Francisco Rogerlândio, Faro, André, Mohammadi, Alireza, Al-Maskari, Fatma, Violante, Francesco S., Truelsen, Thomas, O'Donnell, Martin J., Christopher, Devasahayam Jesudas, Slepak, Erica Leigh, Carrero, Juan Jesus, Nguyen, Quyen Le, Ärnlöv, Johan, Lozano, Rafael, Liu, Patrick Y., Amini, Erfan, Wijeratne, Tissa, Betsu, Balem Demtsu, Mills, Edward J., Cameron, Ewan, El-Khatib, Ziad Ziad, Sibai, Abla Mehio, Mohammed, Kedir Endris, De Leo, Diego, Bulto, Lemma Negesa Bulto, Sposato, Luciano A., Vos, Theo, Heredia-Pi, Ileana Beatriz, Naghavi, Mohsen, Badawi, Alaa, Sobngwi, Eugene, Feyissa, Tesfaye Regassa, Oren, Eyal, Agrawal, Sutapa, Rahimi, Kazem, McAlinden, Colm, Foigt, Nataliya, Wakayo, Tolassa, Zenebe, Zerihun Menlkalew, Chang, Hsing-Yi, Ye, Pengpeng, Kabir, Zubair, Adamu, Abdu Abdullahi, Meretoja, Tuomo J., Skirbekk, Vegard, Sanabria, Juan R., Bedi, Neeraj, Agrawal, Anurag, Hareri, Habtamu Abera, Olagunju, Tinuke Oluwasefunmi, Lim, Stephen S., Al-Raddadi, Rajaa, Gishu, Melkamu Dedefo, Vlassov, Vasiliy Victorovich, Casey, Daniel C., Shinohara, Yukito, Aiyar, Sneha, Asayesh, Hamid, Akseer, Nadia, Tuem, Kald Beshir, Mazidi, Mohsen, Buchbinder, Rachelle, Atey, Tesfay Mehari, Steiner, Timothy J., Al-Aly, Ziyad, Tollanes, Mette C., Alkerwi, Ala'a, Gibney, Katherine B., Jayaraman, Sudha P., Saadat, Soheil, Hernandez, Julio Montañez, Stein, Dan J., Tekelab, Tesfalidet, Salomon, Joshua A., Mruts, Kalayu Birhane, Tandon, Nikhil, Yano, Yuichiro, Afarideh, Mohsen, Resnikoff, Serge, Thrift, Amanda G., McKee, Martin, Beghi, Ettore, Henry, Nathaniel J., Van Boven, Job F.M., Low, Nicola, Ginawi, Ibrahim Abdelmageem Mohamed, Wulf Hanson, Sarah, Gakidou, Emmanuela, Ukwaja, Kingsley N., Satpathy, Maheswar, Parry, Charles D., Remuzzi, Giuseppe, Fernandes, João C., Xu, Gelin, Ammar, Walid, Sykes, Bryan L., Younis, Mustafa Z., Bennett, Derrick A., Prasad, Noela M., Igumbor, Ehimario Uche, London, Stephanie J., Moraga, Paula, Rajsic, Sasa, Franklin, Richard C., Brazinova, Alexandra, Parsaeian, Mahboubeh, Basu, Sanjay, Mezgebe, Haftay Berhane, Crump, John A., Mohammed, Shafiu, Steel, Nicholas, Safdarian, Mahdi, Hao, Yuantao, Barber, Ryan M., Birungi, Charles, Papachristou, Christina, Sartorius, Benn, Martopullo, Ira, Kyu, Hmwe H., Mirrakhimov, Erkin M., Dharmaratne, Samath D., Kim, Pauline, Kahsay, Amaha, Caso, Valeria, Godwin, William W., Ray, Sarah E., Anwari, Palwasha, Dadi, Abel Fekadu, Aichour, Ibtihel, Ahmadieh, Hamid, Micha, Renata, Purcell, Carrie, Wang, Yuan-Pang, Alam, Tahiya, Shirude, Shreya, Muller, Kate, Nguyen, Trang Huyen, Banerjee, Amitava, Vladimirov, Sergey K., Altirkawi, Khalid A., Oladimeji, Olanrewaju, Goto, Atsushi, Murdoch, Michele E., Shrime, Mark G., Ikeda, Chad, Gold, Audra L., Hostiuc, Sorin, Olagunju, Andrew Toyin, Bekele, Bayu Begashaw, Abbas, Kaja M., Chang, Jung-Chen, Mahdavi, Mahdi, Ellerstrand, Jerisha, Hoffman, Howard J., Hankey, Graeme J., Goulart, Alessandra Carvalho, Rahimi-Movaghar, Afarin, Do, Huyen Phuc, Lan, Qing, Moradi-Lakeh, Maziar, Reinig, Nikolas, Lalloo, Ratilal, Ganji, Morsaleh, Olusanya, Jacob Olusegun, Balakrishnan, Kalpana, Shi, Peilin, Naheed, Aliya, Bensenor, Isabela M., Criqui, Michael H., Lambert, Nkurunziza, Garcia-Basteiro, Alberto L., Foreman, Kyle J., Misganaw, Awoke, Aryal, Krishna Kumar, Shaikh, Masood Ali, Biadgilign, Sibhatu, Salvi, Sundeep Santosh, Pillay, Julian David, Aichour, Miloud Taki Eddine, Schöttker, Ben, Poulton, Richie G., Prasad, Narayan, Brugha, Traolach S., Bizuayehu, Habtamu Mellie, Leigh, James, Boufous, Soufiane, Leshargie, Cheru Tesema, Werdecker, Andrea, Nangia, Vinay, Khan, Ejaz Ahmad, Ogbo, Felix Akpojene, Adetokunboh, Olatunji, Wadilo, Fiseha, Htet, Aung Soe, Cirillo, Massimo, Dicker, Daniel, Ribeiro, Antonio L., Shields, Chloe, Giussani, Giorgia, Furtado, Joao M., Djalalinia, Shirin, Kisa, Adnan, Majeed, Azeem, Allebeck, Peter, Boneya, Dube Jara, Rabiee, Rynaz H.S., Barac, Aleksandra, Ngunjiri, Josephine Wanjiku, Ba Saleem, Huda Omer, Reitsma, Marissa B., Khader, Yousef Saleh, Carpenter, David O., Kim, Yun Jin, Ciobanu, Liliana G., Castañeda-Orjuela, Carlos A., Karch, André, Gupta, Rahul, Enayati, Ahmadali, Abajobir, Amanuel Alemu, Carabin, Hélène, Dorsey, E. Ray, Jürisson, Mikk, Moses, Mark, Takala, Jukka S., Assadi, Reza, Sreeramareddy, Chandrashekhar T., Venketasubramanian, Narayanaswamy, Taffere, Getachew Redae, Erskine, Holly E., Goodridge, Amador, Alam, Khurshid, John, Denny, Subart, Michelle, Nolte, Sandra, Seedat, Soraya, Dandona, Rakhi, Fereshtehnejad, Seyed-Mohammad, Johnson, Sarah Charlotte, Flor, Luisa Sorio, Karema, Corine Kakizi, Uneke, Chigozie Jesse, Workicho, Abdulhalik, Kosen, Soewarta, Pa, Mahesh, Pana, Adrian, Malhotra, Rajesh, Meretoja, Atte, Berhane, Adugnaw, Yaghoubi, Mohsen, Aboyans, Victor, Mueller, Ulrich O., Mekonnen, Tefera Chane, Gill, Paramjit Singh, Bhala, Neeraj, Béjot, Yannick, Magdy Abd El Razek, Mohammed, Kumar, Sanjiv, Millear, Anoushka, Katikireddi, Srinivasa Vittal, Horita, Nobuyuki, Hay, Simon I., Thomas, Katie E., Sur, Patrick J., Mountjoy-Venning, Cliff, Tesssema, Belay, Lodha, Rakesh, Looker, Katharine J., Rao, Paturi Vishnupriya, Avokpaho, Euripide Frinel G. Arthur, Nguyen, Cuong Tat, Johnson, Catherine O., Silva, Diego Augusto Santos, Fitzmaurice, Christina, Ferrari, Alize J., Rai, Rajesh Kumar, Irvine, Caleb Mackay Salpeter, Zegeye, Elias Asfaw, Allen, Christine, Shackelford, Katya Anne, Musa, Kamarul Imran, Thamsuwan, Ornwipa, Bazargan-Hejazi, Shahrzad, Carter, Austin, Lee, Jong-Tae, Wolfe, Charles D.A., Santric Milicevic, Milena M., Karam, Nadim E., Lopez, Alan D., Butt, Zahid A., Li, Yongmei, Kivimaki, Mika, Vidavalur, Ramesh, Battista, Bob, Kassebaum, Nicholas J., Carvalho, Felix, Gething, Peter W., Phillips, Michael Robert, Yonemoto, Naohiro, Rahimi-Movaghar, Vafa, Gugnani, Harish Chander, Marczak, Laurie B., Temam Shifa, Girma, Havmoeller, Rasmus, Hailu, Gessessew Bugssa, Tyrovolas, Stefanos, Duncan, Bruce Bartholow, Martinez-Raga, Jose, Whiteford, Harvey A., Fanuel, Fanuel Belayneh Bekele, Alene, Kefyalew Addis, Liu, Yang, Javanbakht, Mehdi, Barker-Collo, Suzanne L., Pourmalek, Farshad, Leasher, Janet L., Deribe, Kebede, Santos, João Vasco, Alla, François, Aichour, Amani Nidhal, Pinho, Christine, Dhillon, Preet Kaur, Abebo, Teshome Abuka, Rahman, Mahfuzar, Negasa, Dumessa Edessa, Mathur, Manu Raj, Woodbrook, Rachel, Taveira, Nuno, Sahathevan, Ramesh, Sunguya, Bruno F., Quansah, Reginald, Macarayan, Erlyn Rachelle King, Ahmad Kiadaliri, Aliasghar, Zipkin, Ben, Qorbani, Mostafa, Stanaway, Jeffrey D., Haro, Josep Maria, Tavakkoli, Mohammad, She, Jun, Mehata, Suresh, Bienhoff, Kelly, Driscoll, Tim R., Mehndiratta, Man Mohan, Dubey, Manisha, Chitheer, Abdulaal A., Huang, Hsiang, Jeemon, Panniyammakal, Pesudovs, Konrad, McNellan, Claire, Al Lami, Faris Hasan, Rafay, Anwar, Fischer, Florian, Hotez, Peter J., Naidoo, Kovin S., Osman, Majdi, Beardsley, Justin, Sousa, Tatiane Cristina Moraes, Khang, Young-Ho, Samy, Abdallah M., Yakob, Bereket, Paulson, Katherine, Atre, Sachin R., Hosgood, H. Dean, Dos Santos, Kadine Priscila Bender, Bourne, Rupert R.A., Khalil, Ibrahim A., Jha, Vivekanand, Kastor, Anshul, Ermakov, Sergey Petrovich, Montico, Marcella, Updike, Rachel, Taylor, Hugh R., Roth, Gregory A., Kinfu, Yohannes, Koyanagi, Ai, Mollenkopf, Sarah K., Atnafu, Niguse Tadele, Sawhney, Monika, Pigott, David M., Asgedom, Solomon W., Kassa, Getachew Mullu, Abu-Raddad, Laith J., Oh, In-Hwan, Zhou, Maigeng, Woolf, Anthony D., Ding, Eric L., Jacobsen, Kathryn H., Weaver, Marcia, Baune, Bernhard T., Yotebieng, Marcel, Artaman, Al, Beuran, Mircea, Plass, Dietrich, Mengistie, Mubarek Abera, Bhutta, Zulfiqar A., Troeger, Christopher, Reiner, Robert C., Mantovani, Lorenzo G., Smith, David L., Keren, Andre, Abdulle, Abdishakur M., Sobaih, Badr H.A., Khubchandani, Jagdish, Newton, Charles R., Kasaeian, Amir, Bhatt, Samir, Safiri, Saeid, Smith, Mari, Shirkoohi, Reza, Hu, Guoqing, Liu, Shiwei, Des Jarlais, Don C., Battle, Katherine E., Zuhlke, Liesl Joanna, Renzaho, Andre M.N., Yip, Paul, Kan, Haidong, Chibueze, Chioma Ezinne, Fullman, Nancy, Endries, Aman Yesuf, Liang, Xiaofeng, Geleto, Ayele, Ruhago, George Mugambage, Filip, Irina, Farzadfar, Farshad, Hamadeh, Randah Ribhi, Amoako, Yaw Ampem, Sadat, Nafis, Alahdab, Fares, Sligar, Amber, Gebrehiwot, Tsegaye Tewelde, Giref, Ababi Zergay, Zhang, Xueying, Chisumpa, Vesper Hichilombwe, McGaughey, Madeline, Logroscino, Giancarlo, Kawakami, Norito, Yimam, Hassen Hamid, Jassal, Simerjot K., Mamun, Abdullah A., Gebre, Teshome, Kumar, Pushpendra, Olusanya, Bolajoko Olubukunola, Tesfaye, Dawit Jember, Berhe, Derbew Fikadu, Cárdenas, Rosario, Stein, Murray B., Fazeli, Mir Sohail, Hassanvand, Mohammad Sadegh, Lavados, Pablo M., Opio, John Nelson, Flaxman, Abraham D., Tripathi, Suryakant, Hawley, Caitlin, Jahanmehr, Nader, Wiysonge, Charles Shey, Abd-Allah, Foad, Li Kappe, Darya, Vasankari, Tommi, De Courten, Barbora, Murthy, Gudlavalleti Venkata Satyanarayana, Hafezi-Nejad, Nima, Pearce, Neil, Tonelli, Marcello, Futran, Neal D., Sigfusdottir, Inga Dora, Patton, George C., Ningrum, Dina Nur Anggraini, Harb, Hilda L., Radfar, Amir, Beyene, Addisu Shunu, Singh, Narinder Pal, Tobe-Gai, Ruoyan, Chibalabala, Mirriam, Rezaei, Satar, Gemechu, Bikila Lencha, Jonas, Jost B., Santomauro, Damian, Cortesi, Paolo Angelo, Sufiyan, Muawiyyah Babale, Srinivasan, Vinay, Awasthi, Ashish, Dey, Subhojit, Kopec, Jacek A., Keiyoro, Peter Njenga, Sepanlou, Sadaf G., Morozoff, Chloe, Bell, Michelle L., Doyle, Kerrie E., Colombara, Danny, Agarwal, Sanjay Kumar, Linn, Shai, Aggarwal, Rakesh, Tiruye, Tenaw Yimer, Memish, Ziad A., Kimokoti, Ruth W., Mensah, George A., Tsoi, Derrick, Nachega, Jean B., Castle, Chris D., Biryukov, Stan, Nichols, Emma, Mirarefin, Mojde, Schmidt, Maria Inês, Eskandarieh, Sharareh, Barrero, Lope H., Ronfani, Luca, Santos, Itamar S., Rankin, Zane, Ortiz, Alberto, Kim, Daniel, Bhansali, Anil, Huynh, Chantal, Lee, Paul H., Yoon, Seok-Jun, Rubagotti, Enrico, Suliankatchi Abdulkader, Rizwan, Bikbov, Boris, Nguyen, Minh, Kuate Defo, Barthelemy, Shamsipour, Mansour, Hoy, Damian G., Rao, Puja C., Gesesew, Hailay Abrha, Tortajada, Miguel, Roshandel, Gholamreza, Kissimova-Skarbek, Katarzyna A., Mantilla, Ana, Sylte, Dillon O., Cahuana-Hurtado, Lucero, Negoi, Ionut, Rahman, Mohammad Hifz Ur, Mishra, Shiva Raj, Schneider, Ione J.C., Ayala Quintanilla, Beatriz Paulina, Krohn, Kristopher J., Stovner, Lars Jacob, Xavier, Denis, Barquera, Simon, Alizadeh-Navaei, Reza, Dellavalle, Robert P., Abbafati, Cristiana, Park, Eun-Kee, Dandona, Lalit, Swaminathan, Soumya, Farinha, Carla Sofia E. Sa, Morrison, Shane D., Nong, Vuong Minh, Strub, Bryan, Silva, João Pedro, Ram, Usha, Degenhardt, Louisa, Shishani, Kawkab, Goldberg, Ellen M., Catalá-López, Ferrán, Bacha, Umar, Gupta, Vipin, Majdan, Marek, Mohanty, Sanjay K., Okoro, Anselm, Ong, Kanyin, Hailu, Alemayehu Desalegne, Manguerra, Helena, Hoek, Hans W., Knudsen, Ann Kristin, Benson, Jennifer, Antonio, Carl Abelardo T., Steinke, Sabine, McGrath, John J., Uthman, Olalekan A., Yadgir, Simon, Perico, Norberto, Osgood-Zimmerman, Aaron, Weintraub, Robert G., Peterson, Carrie Beth, Bärnighausen, Till, Griswold, Max, Jakovljevic, Mihajlo B., Bumgarner, Blair R., Lal, Dharmesh Kumar, Uzochukwu, Benjamin S. Chudi, Schwendicke, Falk, Gupta, Tanush, Ahmed, Muktar Beshir, Ackerman, Ilana N., Chen, Honglei, Nguyen, Grant, Zaki, Maysaa El Sayed, Kadel, Rajendra, Schwebel, David C., Murray, Christopher J.L., Manhertz, Treh, Pereira, David M., Alsowaidi, Shirina, Majdzadeh, Reza, Stathopoulou, Vasiliki, Rawaf, Salman, Iburg, Kim Moesgaard, Kokubo, Yoshihiro, Liu, Angela, Esteghamati, Alireza, Kumar, G. Anil, Das Neves, José, Bisanzio, Donal, Sharma, Jayendra, Bernabé, Eduardo, Shariful Islam, Sheikh Mohammed, Weichenthal, Scott, Vollset, Stein Emil, Alsharif, Ubai, Shigematsu, Mika, Alasfoor, Deena, Harvey, James, Pletcher, Martin A., Ghajar, Alireza, Singh, Jasvinder A., Pacella, Rosana E., Tuzcu, Emin Murat, Patten, Scott B., Heydarpour, Pouria, Bannick, Marlena S., Liben, Misgan Legesse, Skiadaresi, Eirini, Silveira, Dayane Gabriele Alves, Handal, Alexis J., Gona, Philimon N., Yan, Lijing L., Hamidi, Samer, Gupta, Rajeev, Tabarés-Seisdedos, Rafael, Mengistu, Desalegn Tadese, Shaheen, Amira, Westerman, Ronny, Amare, Azmeraw T., Koul, Parvaiz A., Prabhakaran, Dorairaj, Stokes, Mark Andrew, Kolte, Dhaval, Larsson, Anders, Feigin, Valery L., Charlson, Fiona J., Weiderpass, Elisabete, Eshrati, Babak, Akinyemi, Rufus Olusola, Davitoiu, Dragos V., Tran, Bach Xuan, Alam, Noore, Leung, Janni, Afshin, Ashkan, Hay, Roderick J., Kaul, Anil, Krishnaswami, Sanjay, Venkatesh, Magdy Abd El Razek, Hassan, Cooper, Cyrus, Memiah, Peter, Andersen, Hjalte H., Abera, Semaw Ferede, Ranabhat, Chhabi Lal, Levi, Miriam, Mapoma, Chabila C., Mohammad, Karzan Abdulmuhsin, Jiang, Guohong, Roy, Ambuj, Leung, Ricky, Lorkowski, Stefan, Gopalani, Sameer Vali, Kravchenko, Michael, Sorensen, Reed J.D., Kassaw, Nigussie Assefa, Fürst, Thomas, Lucas, Timothy C.D., Car, Mate, and Norrving, Bo
- Subjects
1. No poverty ,10. No inequality ,3. Good health - Abstract
As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016.
40. Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016
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Mereta, Seid Tiku, Shahraz, Saeid, Swaminathan, Soumya, Cooper, Cyrus, Fazeli, Mir Sohail, Majeed, Azeem, Dandona, Lalit, Smith, Mari, Kulikoff, Xie Rachel, Samy, Abdallah M., Faro, André, Ram, Usha, Sur, Patrick J., Bikbov, Boris, Meles, Kidanu Gebremariam, Schwebel, David C., Franklin, Richard C., Kinfu, Yohannes, Ahmadieh, Hamid, John, Denny, Zipkin, Ben, Lazarus, Jeffrey Victor, Skiadaresi, Eirini, Sofia E Sa Farinha, Carla, Carrero, Juan Jesus, Sepanlou, Sadaf G., Ferrari, Alize J., Tandon, Nikhil, Alvis-Guzman, Nelson, Campuzano, Julio Cesar, Djalalinia, Shirin, Driscoll, Tim R., Geleto, Ayele, Das Neves, José, Abu-Rmeileh, Niveen M.E., Dubey, Manisha, Castro, Ruben Estanislao, Chisumpa, Vesper Hichilombwe, Steiner, Caitlyn, Yano, Yuichiro, Ningrum, Dina Nur Anggraini, Mantovani, Lorenzo G., Shaikh, Masood Ali, Silberberg, Donald H., Naheed, Aliya, McGaughey, Madeline, Aboyans, Victor, Santos, João Vasco, Slepak, Erica Leigh, Olusanya, Jacob Olusegun, Leung, Janni, El-Khatib, Ziad Ziad, Miller, Ted R., Yadgir, Simon, Flaxman, Abraham D., Chang, Hsing-Yi, Shifa, Girma Temam, Woldeyes, Belete Getahun, Mirarefin, Mojde, Wolfe, Charles D.A., Breitborde, Nicholas J.K., Reiner, Robert C., DeVeber, Gabrielle A., Huynh, Chantal, Blancas, Maria Jesus Rios, Mokdad, Ali H., Garcia-Basteiro, Alberto L., Alam, Khurshid, Schutte, Aletta E., Whiteford, Harvey A., Fereshtehnejad, Seyed-Mohammad, Obermeyer, Carla Makhlouf, Larsson, Anders, Kastor, Anshul, Manguerra, Helena, Frostad, Joseph J., Radfar, Amir, Meretoja, Atte, Farzadfar, Farshad, Kiadaliri, Aliasghar Ahmad, Tabarés-Seisdedos, Rafael, Allebeck, Peter, Aichour, Amani Nidhal, Lotufo, Paulo A., Avila-Burgos, Leticia, He, Jiawei, Nguyen, Grant, Amare, Azmeraw T., Musa, Kamarul Imran, Roshandel, Gholamreza, Kasaeian, Amir, Hankey, Graeme J., Beghi, Ettore, Frank, Tahvi, Lodha, Rakesh, Tegegne, Teketo Kassaw, Thrift, Amanda G., Tao, Tianchan, Yan, Lijing L., Malhotra, Rajesh, Reinig, Nikolas, Nguyen, Minh, Goryakin, Yevgeniy, Vlassov, Vasiliy Victorovich, Furtado, Joao M., Gopalani, Sameer Vali, Mohammad, Karzan Abdulmuhsin, Satpathy, Maheswar, Foigt, Nataliya, Sligar, Amber, Pigott, David M., Dargan, Paul I., Paulson, Katherine, Ye, Pengpeng, Sartorius, Benn, Holmberg, Mollie, Nguyen, Quyen Le, Roba, Kedir Teji, Zhang, Xueying, Asgedom, Solomon Weldegebreal, Stokes, Mark Andrew, El Razek, Mohammed Magdy Abd, Smith, Alison, Wiysonge, Charles Shey, Sunguya, Bruno F., Rokni, Mohammad Bagher, McKee, Martin, Enayati, Ahmadali, Ur Rahman, Mohammad Hifz, Lopez, Alan D., Majdan, Marek, Bilal, Arebu I., Sufiyan, Muawiyyah Babale, Mollenkopf, Sarah K., Jahanmehr, Nader, Kumar, G. Anil, Berhe, Derbew Fikadu, Khang, Young-Ho, Memish, Ziad A., Panda-Jonas, Songhomitra, Koul, Parvaiz A., Irvine, Caleb Mackay Salpeter, Lansingh, Van C., Salama, Joseph, Mengesha, Melkamu Merid, Ding, Eric L., Pana, Adrian, Schneider, Matthew T., Park, Eun-Kee, Alsharif, Ubai, Cárdenas, Rosario, Kutz, Michael J., Santos, Itamar S., Kim, Daniel, Bidgoli, Hassan Haghparast, Olagunju, Tinuke Oluwasefunmi, Meier, Toni, Shiferaw, Mekonnen Sisay, Alizadeh-Navaei, Reza, Bhansali, Anil, Shrime, Mark G., Alla, François, Kivimaki, Mika, Nong, Vuong Minh, Pourmalek, Farshad, Chitheer, Abdulaal A., Singh, Jasvinder A., Sylte, Dillon O., Bennett, Derrick A., Gupta, Tanush, Adedeji, Isaac Akinkunmi, Shirkoohi, Reza, Vos, Theo, Kravchenko, Michael, Minnig, Shawn, Schneider, Ione J.C., Renzaho, Andre M.N., Mengistie, Mubarek Abera, Lim, Stephen S., Linn, Shai, De Steur, Hans, Mezgebe, Haftay Berhane, Van Donkelaar, Aaron, Bensenor, Isabela M., Santric Milicevic, Milena M., Khan, Ejaz Ahmad, Asayesh, Hamid, Truelsen, Thomas, Hareri, Habtamu Abera, McGrath, John J., Dandona, Rakhi, Lozano, Rafael, Kissimova-Skarbek, Katarzyna A., Yimam, Hassen Hamid, Catalá-López, Ferrán, Venketasubramanian, Narayanaswamy, Yonemoto, Naohiro, Akinyemi, Rufus Olusola, Al-Aly, Ziyad, Looker, Katharine J., Horita, Nobuyuki, Malta, Deborah Carvalho, Gakidou, Emmanuela, Eshrati, Babak, Cahuana-Hurtado, Lucero, Resnikoff, Serge, Gibney, Katherine B., Levi, Miriam, Gupta, Vipin, Giref, Ababi Zergaw, Kemmer, Laura, Soljak, Michael, Kawakami, Norito, Hostiuc, Sorin, Oren, Eyal, Abu-Raddad, Laith J., Safiri, Saeid, Tran, Bach Xuan, Rafay, Anwar, Servan-Mori, Edson E., Abd-Allah, Foad, Feigl, Andrea B., Jha, Vivekanand, Tortajada, Miguel, Pillay, Julian David, Charlson, Fiona J., Thakur, Awasthi, Ashish, Carabin, Hélène, Bell, Michelle L., Beyene, Addisu Shunu, Kesavachandran, Chandrasekharan Nair, Filip, Irina, Pinho, Christine, Tarekegn, Yihunie L., Ermakov, Sergey Petrovich, Mohammed, Kedir Endris, Fullman, Nancy, Sanabria, Juan Ramon, Mazidi, Mohsen, Ebrahimi, Hedyeh, Weiss, Daniel J., Majdzadeh, Reza, Abdulle, Abdishakur M., Tadakamadla, Santosh Kumar, Brauer, Michael, Birungi, Charles, Kieling, Christian, Balakrishnan, Kalpana, Rahman, Muhammad Aziz, Rai, Rajesh Kumar, Liu, Patrick Y., Tuem, Kald Beshir, Stein, Dan J., Nangia, Vinay, Safi, Sare, Foreman, Kyle J., Shibuya, Kenji, Perico, David Norberto, Phillips, Michael Robert, Sykes, Bryan L., Alam, Noore, De Courten, Barbora, Khubchandani, Jagdish, Uneke, Chigozie Jesse, Liben, Misgan Legesse, Deiparine, Selina, Inoue, Manami, Tyrovolas, Stefanos, Schmidt, Maria Inês, Esteghamati, Alireza, Li, Yongmei, Cameron, Ewan, Misganaw, Awoke, Santomauro, Damian, Shaheen, Amira, Millear, Anoushka, Karch, André, Abdulkader, Rizwan Suliankatchi, Criqui, Michael H., Olusanya, Bolajoko Olubukunola, Shields, Chloe, Silva, Diego Augusto Santos, Sreeramareddy, Chandrashekhar T., Atey, Tesfay Mehari, Islam, Sheikh Mohammed Shariful, Kelbore, Sefonias Getachew, Smith, David L., Soneji, Samir, Sadat, Nafis, Abajobir, Amanuel Alemu, Reidy, Patrick, Aryal, Krishna Kumar, Martinez-Raga, Jose, Deribe, Kebede, Szoeke, Cassandra E.I., Negoi, Ionut, Shishani, Kawkab, Yaseri, Mehdi, Kim, Yun Jin, Goodridge, Amador, Roy, Ambuj, Agrawal, Anurag, Hafezi-Nejad, Nima, Ammar, Walid, Hammami, Mouhanad, Shamsizadeh, Morteza, Brugha, Traolach S., Shin, Min-Jeong, Nichols, Emma, Silveira, Dayane Gabriele Alves, Manyazewal, Tsegahun, Jonas, Jost B., Roth, Gregory A., Griswold, Max, Micha, Renata, Steinke, Sabine, Fischer, Florian, Jakovljevic, Mihajlo B., Chew, Adrienne, Mohammed, Shafiu, Arora, Megha, Kahsay, Amaha, Younis, Mustafa Z., Sagar, Rajesh, Endries, Aman Yesuf, Hosgood, H. Dean, Gemechu, Bikila Lencha, Gishu, Melkamu Dedefo, Woodbrook, Rachel, Wakayo, Tolassa, Tobe-Gai, Ruoyan, Tessema, Gizachew Assefa, Rivas, Jacqueline Castillo, Werdecker, Andrea, Schwendicke, Falk, Feyissa, Tesfaye Regassa, Kamal, Ritul, Abbafati, Cristiana, Stanaway, Jeffrey D., Karema, Corine Kakizi, Mehndiratta, Man Mohan, Doku, David Teye, Bhala, Neeraj, Bhutta, Zulfiqar A., Ebel, Beth E., Chang, Jung-Chen, Dokova, Klara, Betsu, Balem Demtsu, Vidavalur, Ramesh, Barrero, Lope H., Javanbakht, Mehdi, Nguyen, Trang Huyen, Papachristou, Christina, Lalloo, Ratilal, Ukwaja, Kingsley N., Wadilo, Fiseha, Mensink, Gert B.M., Piradov, Michael A., Iburg, Kim Moesgaard, Oh, In-Hwan, Butt, Zahid A., Anwari, Palwasha, Yip, Paul, Akseer, Nadia, Saxena, Sonia, Ahmed, Muktar Beshir, Amini, Erfan, Zaidi, Zoubida, Thankappan, Kavumpurathu Raman, Violante, Francesco S., Beardsley, Justin, Afshin, Ashkan, Panda, Basant Kumar, Huang, John J., Friedman, Joseph, Oladimeji, Olanrewaju, Muller, Kate, Do, Huyen Phuc, Leung, Ricky, Martopullo, Ira, Bou-Orm, Ibrahim R., Bannick, Marlena S., Jacobsen, Kathryn H., Fernandes, João C., Jauregui, Alejandra, Béjot, Yannick, Yotebieng, Marcel, Sawhney, Monika, Mensah, George A., Ogbo, Felix Akpojene, Kokubo, Yoshihiro, Cirillo, Massimo, Tiruye, Tenaw Yimer, Malekzadeh, Reza, Koyanagi, Ai, Ong, Kanyin, Jürisson, Mikk, Arthur Avokpaho, Euripide Frinel G., Bernabé, Eduardo, Basu, Sanjay, Safdarian, Mahdi, Topor-Madry, Roman, Carter, Austin, Adetokunboh, Olatunji, Casey, Daniel C., Remuzzi, Giuseppe, Mamun, Abdullah A., Alasfoor, Deena, Abbas, Kaja M., Battle, Katherine E., Mishra, Shiva Raj, Troeger, Christopher, Blosser, Christopher D., Singh, Virendra, Abera, Semaw Ferede, Gething, Peter W., Gona, Philimon N., Gill, Paramjit Singh, Silva, João Pedro, Davitoiu, Dragos V., Sobngwi, Eugene, Schöttker, Ben, Castañeda-Orjuela, Carlos A., Hay, Simon I., Khalil, Ibrahim A., McAlinden, Colm, Dorsey, E. Ray, Naidoo, Kovin S., Montico, Marcella, Hoek, Hans W., Johnson, Catherine O., Hsairi, Mohamed, Khader, Yousef Saleh, Henry, Nathaniel J., Weichenthal, Scott, Poulton, Richie G., Vladimirov, Sergey K., Kimokoti, Ruth W., Torre, Anna, Htet, Aung Soe, Olivares, Pedro R., Alene, Kefyalew Addis, Hassanvand, Mohammad Sadegh, Boneya, Dube Jara, Antonio, Carl Abelardo T., Rawaf, Salman, Eskandarieh, Sharareh, Lal, Dharmesh Kumar, Terkawi, Abdullah Sulieman, Bärnighausen, Till, Negoi, Ruxandra Irina, Kassebaum, Nicholas J., Ortiz, Alberto, Fitzmaurice, Christina, Moradi-Lakeh, Maziar, Hendrie, Delia, Mitchell, Philip B., Noubiap, Jean Jacques N., Sobaih, Badr H.A., Jeemon, Panniyammakal, Martins-Melo, Francisco Rogerlândio, She, Jun, Mountjoy-Venning, Cliff, Defo, Barthelemy Kuate, Natarajan, Gopalakrishnan, Sharma, Jayendra, Bulto, Lemma Negesa Bulto, Owolabi, Mayowa O., Reitsma, Marissa B., Al-Raddadi, Rajaa, Seedat, Soraya, Barker-Collo, Suzanne L., Shiri, Rahman, Aiyar, Sneha, Katikireddi, Srinivasa Vittal, Gugnani, Harish Chander, Sposato, Luciano A., Bacha, Umar, Havmoeller, Rasmus, Rao, Puja C., Khosravi, Ardeshir, Tavakkoli, Mohammad, Godwin, William W., Kopec, Jacek A., Mueller, Ulrich O., Gillum, Richard F., Shi, Peilin, Berhane, Adugnaw, Altirkawi, Khalid A., Bizuayehu, Habtamu Mellie, Morawska, Lidia, Mohan, Murali B.V., Yakob, Bereket, Bhatt, Samir, Sharma, Rajesh, Tsoi, Derrick, Kengne, Andre Pascal, Nomura, Marika, Glenn, Scott D., Barber, Ryan M., Shirude, Shreya, Feigin, Valery L., Strub, Bryan, Weintraub, Robert G., Crump, John A., Atre, Sachin R., Tuzcu, Emin Murat, Baune, Bernhard T., Abate, Kalkidan Hassen, Mathur, Manu Raj, Cercy, Kelly, Marks, Guy B., Christopher, Devasahayam Jesudas, Xu, Gelin, Pishgar, Farhad, Hailu, Gessessew Bugssa, Bose, Dipan, Giussani, Giorgia, Srinivasan, Vinay, Olsen, Helen E., Gupta, Rajeev, El Sayed Zaki, Maysaa, Rajsic, Sasa, Aichour, Miloud Taki Eddine, Kabir, Zubair, Qorbani, Mostafa, Kim, Jun Y., Goldberg, Ellen M., Moraga, Paula, Westerman, Ronny, Lunevicius, Raimundas, Mirrakhimov, Erkin M., Hawley, Caitlin, Nguyen, Cuong Tat, Beuran, Mircea, Alkerwi, Ala'a, Leigh, James, Ansari, Hossein, Monasta, Lorenzo, Huang, Hsiang, Lorkowski, Stefan, Hernandez, Julio Cesar Montañez, Shamsipour, Mansour, Varughese, Santosh, Patton, George C., Rahimi-Movaghar, Vafa, Keiyoro, Peter Njenga, Agrawal, Sutapa, Erskine, Holly E., Maddison, Emilie R., Petzold, Max, Xavier, Denis, Ranabhat, Chhabi Lal, Murthy, Gudlavalleti Venkata Satyanarayana, Rojas-Rueda, David, Rubagotti, Enrico, Johnson, Sarah Charlotte, Mackay, Mark T., Naghavi, Mohsen, Artaman, Al, Wijeratne, Tissa, Wallin, Mitchell T., Liu, Shiwei, Mehata, Suresh, Meretoja, Tuomo J., Duncan, Bruce Bartholow, Sorensen, Reed J.D., Biryukov, Stan, Salomon, Joshua A., Lee, Paul H., Shigematsu, Mika, Faraon, Emerito Jose Aquino, Saylan, Mete I., Aichour, Ibtihel, Kyu, Hmwe H., Ikeda, Chad, Martin, Randall V., Krohn, Kristopher J., Sinha, Dhirendra Narain, Bedi, Neeraj, Zodpey, Sanjay, Olagunju, Andrew Toyin, Yoon, Seok-Jun, Cromwell, Elizabeth A., Kadel, Rajendra, Mapoma, Chabila C., Morrison, Shane D., Rahman, Mahfuzar, Vasankari, Tommi, Azzopardi, Peter, Wang, Yuan-Pang, Kosen, Soewarta, Heredia-Pi, Ileana Beatriz, Vollset, Stein Emil, Fürst, Thomas, Pesudovs, Konrad, Gebrehiwot, Tsegaye Tewelde, Shoman, Haitham, Bicer, Burcu Kucuk, Degenhardt, Louisa, Pereira, David M., Badawi, Alaa, Taveira, Nuno, Norheim, Ole F., El Razek, Hassan Magdy Abd, Geleijnse, Johanna M., Kisa, Adnan, Rezaei, Satar, Estep, Kara, Bennett, James R., Uthman, Olalekan A., Mendoza, Walter, Hoy, Damian G., Harb, Hilda L., Barac, Aleksandra, Hamadeh, Randah Ribhi, Christensen, Hanne, Lucas, Timothy C.D., Assadi, Reza, Allen, Christine, Shackelford, Katya Anne, Van Boven, Job F.M., Moses, Mark W., Mahesh, Zavala-Arciniega, Luis, Weiderpass, Elisabete, Murray, Christopher J.L., and Updike, Rachel
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1. No poverty ,10. No inequality ,3. Good health - Abstract
The UN’s Sustainable Development Goals (SDGs) are grounded in the global ambition of “leaving no one behind”. Understanding today’s gains and gaps for the health-related SDGs is essential for decision makers as they aim to improve the health of populations. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016), we measured 37 of the 50 health-related SDG indicators over the period 1990–2016 for 188 countries, and then on the basis of these past trends, we projected indicators to 2030.
41. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016: a systematic analysis for the Global Burden of Disease Study 2016
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Stöckl, Heidi, Anwari, Palwasha, Agrawal, Sutapa, Al-Raddadi, Rajaa, Castañeda-Orjuela, Carlos A., Kim, Daniel, Graetz, Nicholas, Ali, Raghib, Jonas, Jost B., Gibney, Katherine B., Coresh, Josef, Kaul, Anil, Majdzadeh, Reza, Franklin, Richard C., Remuzzi, Giuseppe, Mezgebe, Haftay Berhane, Silva, João Pedro, Yonemoto, Naohiro, Kuipers, Ernst J., Ileanu, Bogdan Vasile, Massano, João, Saxena, Sonia, Yip, Paul, Majdan, Marek, Perez-Ruiz, Fernando, Castillo Rivas, Jacqueline, Gankpé, Fortuné Gbètoho, Kadel, Rajendra, Soriano, Joan B., Hambisa, Mitiku Teshome, Tuzcu, Emin Murat, Karch, André, Ciobanu, Liliana G., Esteghamati, Alireza, Pourmalek, Farshad, Martinez-Raga, Jose, Kibret, Getiye Dejenu, Das Neves, José, Sanchez-Niño, Maria Dolores, Sepanlou, Sadaf G., Kulikoff, Xie Rachel, Baune, Bernhard T., Mazidi, Mohsen, Ayala Quintanilla, Beatriz Paulina, Gesesew, Hailay Abrha, Gillum, Richard F., Natarajan, Gopalakrishnan, Karthikeyan, Ganesan, Silberberg, Donald H., Kishawi, Sami, Rawaf, Salman, Resnikoff, Serge, Allebeck, Peter, Bärnighausen, Till, Bennett, James R., Tarajia, Musharaf, Chibalabala, Mirriam, Barregard, Lars, Cirillo, Massimo, Alahdab, Fares, McGrath, John J., Lal, Dharmesh Kumar, Petri, William Arthur, Lachat, Carl, Sagar, Rajesh, Zeeb, Hajo, Alsharif, Ubai, Deribew, Amare, Herteliu, Claudiu, Xu, Gelin, Patel, Tejas, Ding, Eric L., Shibuya, Kenji, Davey, Gail, Misganaw, Awoke, Tekle, Dejen Yemane, Schwendicke, Falk, Barrero, Lope H., Mekonnen, Tefera Chane, Leigh, James, Lee, Paul H., Islam, Sheikh Mohammed Shariful, Bell, Michelle L., Car, Josip, Balalla, Shivanthi, Pishgar, Farhad, Kastor, Anshul, Feigin, Valery L., Dubey, Manisha, Uthman, Olalekan A., Gupta, Rajeev, Alkaabi, Juma M., Nachega, Jean B., Mantovani, Lorenzo G., Sharma, Jayendra, Hassanvand, Mohammad Sadegh, Lipshultz, Steven E., Bhala, Neeraj, Mohammadi, Alireza, Menon, Geetha R., Sobaih, Badr H.A., Abu-Raddad, Laith J., Kamal, Ritul, Adedeji, Isaac Akinkunmi, Vollset, Stein Emil, Barac, Aleksandra, Vasankari, Tommi, Lorch, Scott A., Meier, Toni, Vladimirov, Sergey K., Rubagotti, Enrico, Campos-Nonato, Ismael Ricardo, Horita, Nobuyuki, Polinder, Suzanne, Woldeyes, Belete Getahun, Vasconcelos, Ana Maria Nogales, Kim, Pauline, Bisanzio, Donal, Dandona, Rakhi, Fanuel, Fanuel Belayneh Bekele, Johnson, Sarah Charlotte, Lansingh, Van C., Larsson, Anders, Mengistu, Desalegn Tadese, Kesavachandran, Chandrasekharan Nair, Khosravi, Mohammad Hossein, Mooney, Meghan D., Cahuana-Hurtado, Lucero, Murthy, Gudlavalleti Venkata Satyanarayana, Genova-Maleras, Ricard, Liben, Misgan Legesse, Bazargan-Hejazi, Shahrzad, Laryea, Dennis Odai, Deribe, Kebede, Shigematsu, Mika, Jensen, Paul N., Brenner, Hermann, Nong, Vuong Minh, Nagel, Gabriele, Gambashidze, Ketevan, Stein, Dan J., Gona, Philimon N., Htet, Aung Soe, Geleijnse, Johanna M., Dandona, Lalit, Shiue, Ivy, Chiang, Peggy Pei-Chia, Haghparast Bidgoli, Hassan, Bumgarner, Blair Randal, Skiadaresi, Eirini, Okoro, Anselm, Frank, Tahvi, Irvine, Caleb M.S., Asayesh, Hamid, Mackay, Mark T., Kahsay, Amaha, Gopalani, Sameer Vali, Katikireddi, Srinivasa Vittal, Alizadeh-Navaei, Reza, Mokdad, Ali H., Al-Eyadhy, Ayman, Park, Eun-Kee, Pereira, David M., Satpathy, Maheswar, Yan, Lijing L., Bulto, Lemma Negesa Bulto, Islam, Nazrul, Djalalinia, Shirin, Donnelly, Christl Ann, Mehndiratta, Man Mohan, Topor-Madry, Roman, Yirsaw, Biruck Desalegn, Bacha, Umar, Rajsic, Sasa, Abajobir, Amanuel Alemu, Varughese, Santosh, Alla, François, Avila-Burgos, Leticia, Tadakamadla, Santosh Kumar, Kabir, Zubair, Tekelab, Tesfalidet, Alvis-Guzman, Nelson, Afshin, Ashkan, Lodha, Rakesh, Duncan, Bruce Bartholow, Lotufo, Paulo A., Endries, Aman Yesuf, Nomura, Marika, Gupta, Vipin, Nguyen, Quyen Le, Mohammad, Karzan Abdulmuhsin, Sanabria, Juan Ramon, Ameh, Emmanuel A., Swaminathan, Soumya, Popova, Svetlana, Krohn, Kristopher J., Anber, Nahla, Martin, Elena Alvarez, Seid, Abdulbasit Musa, Stathopoulou, Vasiliki, Thomson, Alan J., Rezaei, Satar, Ahmad Kiadaliri, Aliasghar, Lunevicius, Raimundas, Carpenter, David O., Sarmiento-Suarez, Rodrigo, Keiyoro, Peter Njenga, Douwes-Schultz, Dirk, Uzochukwu, Benjamin S. Chudi, Noubiap, Jean Jacques N., Sur, Patrick J., Mohammed, Kedir Endris, Macarayan, Erlyn Rachelle King, Farzadfar, Farshad, Aichour, Ibthiel, Hammami, Mouhanad, Gemechu, Kasiye Shiferaw, Hareri, Habtamu Abera, Hao, Yuantao, Dos Santos, Kadine Priscila Bender, Nguyen, Grant, Hostiuc, Sorin, Sligar, Amber, Roshandel, Gholamreza, Safdarian, Mahdi, Brazinova, Alexandra, Rabiee, Rynaz H.S., Sahathevan, Ramesh, Cromwell, Elizabeth A., Olagunju, Andrew Toyin, Perico, Norberto, Renzaho, Andre M.N.N., Rahimi-Movaghar, Afarin, Magdy Abd El Razek, Mohammed, Musa, Kamarul Imran, Rahman, Mahfuzar, Rana, Saleem M., Bensenor, Isabela M., Pervaiz, Aslam, Ronfani, Luca, Weintraub, Robert G., Zhang, Anthony Lin, Jeemon, Panniyammakal, Strong, Mark, Martins-Melo, Francisco Rogerlândio, Kissoon, Niranjan, Mills, Edward J., Terkawi, Abdullah Sulieman, Li, Yongmei, Mehta, Kala M., Thrift, Amanda G., Moore, Ami R., Driscoll, Tim R., Poulton, Richie G., Yalew, Ayalnesh Zemene, Kucuk Bicer, Burcu, Kokubo, Yoshihiro, Castro, Franz F., Yotebieng, Marcel, Pakhale, Smita, Kulkarni, Veena S., Tavakkoli, Mohammad, Tehrani-Banihashemi, Arash, Machado, Isis Eloah, Malekzadeh, Reza, Silpakit, Naris, Hosgood, H. Dean, Barker-Collo, Suzanne L., Marczak, Laurie B., Gebrekidan, Kahsu Gebrekirstos, Javanbakht, Mehdi, Carrero, Juan Jesus, Montañez Hernandez, Julio Cesar, Foreman, Kyle J., Hamidi, Samer, Pana, Adrian, Sreeramareddy, Chandrashekhar T., Zodpey, Sanjay, Tobe-Gai, Ruoyan, Estep, Kara, Ketema, Ezra Belay, Mirarefin, Mojde, Karimi, Seyed M., Sahebkar, Amirhossein, Akanda, Ali Shafqat, Murthy, Srinivas, Ellingsen, Christian Lycke, Kissimova-Skarbek, Katarzyna A., Kassaw, Nigussie Assefa, Nascimento, Bruno Ramos, Micha, Renata, Zuhlke, Liesl Joanna, Meretoja, Atte, Amare, Azmeraw T., Piel, Frédéric B., Norrving, Bo, Wang, Haidong, Chisumpa, Vesper Hichilombwe, Leung, Ricky, Hafezi-Nejad, Nima, Amoako, Yaw Ampem, Levi, Miriam, Undurraga, Eduardo A., Menota, Bereket Gebremichael, Rai, Rajesh Kumar, Mahdavi, Mahdi, Allam, Shalini D., Silveira, Dayane Gabriele Alves, Tadese, Fentaw, Soneji, Samir, Weichenthal, Scott, Doku, David Teye, Gill, Paramjit Singh, Varakin, Yuri Y., Deiparine, Selina, Barquera, Simon, Mahesh, Foigt, Nataliya, Saylan, Mete I., Shiri, Rahman, Van Boven, Job F.M., Des Jarlais, Don C., Dwivedi, Laxmi Kant, Gupta, Tanush, Ningrum, Dina Nur Anggraini, Kelbore, Sefonias Getachew, Dherani, Mukesh K., Lalloo, Ratilal, Artaman, Al, Davletov, Kairat, Kutz, Michael, Mollenkopf, Sarah K., Haagsma, Juanita A., Salamati, Payman, Yaghoubi, Mohsen, Vlassov, Vasiliy Victorovich, De Courten, Barbora, Wilkinson, James D., Suliankatchi, Rizwan Abdulkader, Sufiyan, Muawiyyah Babale, Assadi, Reza, Sunguya, Bruno F., Choi, Jee-Young Jasmine, Schneider, Ione J.C., Oh, In-Hwan, Shackelford, Katya Anne, Nangia, Vinay, Rahimi-Movaghar, Vafa, Cahill, Leah E., Yimam, Hassen Hamid, Bourne, Rupert R.A., Tesema, Cheru Leshargie, Mullany, Erin, Salvi, Sundeep Santosh, Aljunid, Syed M., Abate, Kalkidan Hassen, Fürst, Thomas, Davitoiu, Dragos V., Montico, Marcella, Stokes, Mark Andrew, Hay, Simon I., Hoek, Hans W., Sabde, Yogesh Damodar, Cárdenas, Rosario, Malta, Deborah Carvalho, Kemp, Andrew Haddon, Liao, Yu, Ota, Erika, Hay, Roderick J., Leung, Janni, Rothenbacher, Dietrich, Boufous, Soufiane, Irenso, Asnake Ararsa, Khera, Sahil, Smith, David L., Gebregergs, Gebremedhin Berhe, Mehata, Suresh, Bhutta, Zulfiqar A., Castro, Ruben Estanislao, Tiruye, Tenaw Yimer, Patton, George C., Moradi-Lakeh, Maziar, Mohanty, Sanjay K., Temam Shifa, Girma, Ye, Pengpeng, Oren, Eyal, Plass, Dietrich, Mohan, Murali B.V., Rokni, Mohammad Bagher, Alkerwi, Ala'a, Khan, Gulfaraz, Degenhardt, Louisa, Frostad, Joseph J., Alam, Khurshid, Nagata, Chie, Fereshtehnejad, Seyed-Mohammad, Filip, Irina, Radfar, Amir, Dellavalle, Robert P., Kopec, Jacek A., Hotez, Peter J., Gemechu, Bikila Lencha, Babalola, Tesleem Kayode, Meles, Kidanu Gebremariam, McAlinden, Colm, Waid, Jillian L., Majeed, Azeem, Heredia-Pi, Ileana Beatriz, Morrison, Shane D., Owolabi, Mayowa O., Knudsen, Ann Kristin, Singh, Abhishek, Amini, Erfan, Criqui, Michael H., Singh, Prashant Kumar, Topouzis, Fotis, Shetty, Balakrishna P., Kieling, Christian, Boneya, Dube Jara, Bennett, Derrick A., Meretoja, Tuomo J., Kassebaum, Nicholas J., Ranabhat, Chhabi Lal, Zaidi, Zoubida, Petzold, Max, Abbafati, Cristiana, Logroscino, Giancarlo, Maulik, Pallab K., Balakrishnan, Kalpana, Lager, Anton Carl Jonas, Lim, Stephen S., Jha, Vivekanand, Mendoza, Walter, Igumbor, Ehimario Uche, Singh, Jasvinder A., Sharma, Rajesh, Harb, Hilda L., Bhaumik, Soumyadeep, Salama, Joseph, Kivimaki, Mika, Lagat, Abraham K., Wiysonge, Charles Shey, Khan, Ejaz Ahmad, Dargan, Paul I., Zenebe, Zerihun Menlkalew, Alam, Noore, Lan, Qing, Rahman, Sajjad Ur, Biryukov, Stan, Purwar, Manorama, Younis, Mustafa Z., Workie, Shimelash Bitew, Qorbani, Mostafa, Fernandes, Jefferson G., Androudi, Sofia, Ahmed, Muktar Beshir, Schmidt, Maria Inês, Panda-Jonas, Songhomitra, Karema, Corine Kakizi, Harikrishnan, Sivadasanpillai, Carter, Austin, Ermakov, Sergey Petrovich, Wijeratne, Tissa, Lorkowski, Stefan, Inoue, Manami, Kan, Haidong, Gupta, Prakash C., Beyene, Addisu Shunu, Beuran, Mircea, Shen, Jiabin, Keren, Andre, Arora, Megha, Berhe, Derbew Fikadu, Futran, Neal D., Gebremichael, Mengistu Welday, Shaheen, Amira, Mensah, George A., Safi, Sare, Hamadeh, Randah Ribhi, Bernabé, Eduardo, Sindi, Shireen, Bukhman, Gene, Gebrehiwot, Tsegaye Tewelde, Perez-Padilla, Rogelio, Moraga, Paula, Seedat, Soraya, Schwebel, David C., Asghar, Rana Jawad, Steiner, Caitlyn, Shamsipour, Mansour, Jahanmehr, Nader, Kravchenko, Michael, Nguyen, Cuong Tat, Akinyemiju, Tomi F., Hilawe, Esayas Haregot, Faro, André, Manyazewal, Tsegahun, Iburg, Kim Moesgaard, Singh, Virendra, Adetifa, Ifedayo Morayo O., Kumar, G. Anil, Phillips, Michael Robert, Al-Aly, Ziyad, Khoja, Abdullah Tawfih Abdullah, Monasta, Lorenzo, Jacobsen, Kathryn H., Bjerregaard, Peter, Negoi, Ionut, Moreno Velasquez, Ilais, Workicho, Abdulhalik, Kumsa, Fekede Asefa, Obermeyer, Carla Makhlouf, Fernandes, João C., Brugha, Traolach S., Hoy, Damian G., Sigfusdottir, Inga Dora, Panda, Basant Kumar, Minnig, Shawn, Safiri, Saeid, Rego, Maria Albertina Santiago, Giref, Ababi Zergaw, Oyekale, Abayomi Samuel, Tabarés-Seisdedos, Rafael, Bhansali, Anil, Gething, Peter W., Barber, Ryan M., Zhang, Xueying, Kim, Yun Jin, Ruhago, George Mugambage, Samy, Abdallah M., Bedi, Neeraj, Osgood-Zimmerman, Aaron, Kosen, Soewarta, Mapoma, Chabila C., Agrawal, Anurag, Ortiz, Alberto, Burch, Michael, Barboza, Miguel A., Naidoo, Kovin S., McGarvey, Stephen Theodore, Sachdev, Perminder S., Aldridge, Robert William, Awasthi, Ashish, Lambert, Nkurunziza, Mori, Rintaro, Tran, Bach Xuan, Reiner, Robert C., Rezai, Mohammad Sadegh, Thomas, Nihal, Olusanya, Jacob Olusegun, Prasad, Narayan, Ram, Usha, Yano, Yuichiro, Roth, Gregory A., Miller, Ted R., Thompson, Alex H., Badawi, Alaa, Malhotra, Rajesh, Adetokunboh, Olatunji, Jaenisch, Thomas, Dharmaratne, Samath D., Rehm, Jürgen, Salomon, Joshua A., Theis, Andrew, Abu-Rmeileh, Niveen M.E., Lavados, Pablo M., Pesudovs, Konrad, Mengesha, Melkamu Merid, Saadat, Soheil, Ansari, Hossein, Alasfoor, Deena, Furtado, Joao M., Butt, Zahid A., Aggarwal, Rakesh, Haro, Josep Maria, Tesssema, Belay, Paudel, Deepak, Rao, Paturi Vishnupriya, Birungi, Charles, Santos, Itamar S., Yakob, Bereket, Sartorius, Benn, Vishnu, Abhishek, Koyanagi, Ai, El Bcheraoui, Charbel, Shahraz, Saeid, Nanda, Lipika, Beghi, Ettore, Mirrakhimov, Erkin M., Tuem, Kald Beshir, Atey, Tesfay Mehari, Do, Huyen Phuc, Wang, Yuan-Pang, Rahman, Mohammad Hifz Ur, Vos, Theo, Peterson, Carrie Beth, Rafay, Anwar, Gugnani, Harish Chander, Hancock, Jamie, Silva, Diego Augusto Santos, Zerfu, Taddese Alemu, Abd-Allah, Foad, McKee, Martin, Ribeiro, Antonio L., Giussani, Giorgia, Linn, Shai, Aryal, Krishna Kumar, Xavier, Denis, Wolfe, Charles D.A., Nisar, Muhammad Imran, Adedoyin, Rufus Adesoji, Dixit, Priyanka, Akseer, Nadia, Murray, Christopher J.L., Gelaye, Amha Admasie, Duan, Leilei, Ansha, Mustafa Geleto, Asgedom, Solomon Weldegebreal, Girma, Bedilu Weji, Sadat, Nafis, Laxmaiah, Avula, Venketasubramanian, Narayanaswamy, Nguyen, Trang Huyen, Larson, Heidi J., Eskandarieh, Sharareh, Santric Milicevic, Milena M., Fullman, Nancy, Vidavalur, Ramesh, Garcia-Basteiro, Alberto L., Werdecker, Andrea, Tanne, David, Molokhia, Mariam, De Leo, Diego, John, Oommen, Halasa, Yara A., Kim, Cho-Il, Kereselidze, Maia, Eshrati, Babak, Berhane, Adugnaw, Naghavi, Mohsen, Lozano, Rafael, Aichour, Miloud Taki Eddine, Gomez, Beatriz, Andrei, Catalina Liliana, Kumar, Pushpendra, John, Denny, Hsairi, Mohamed, Marks, Guy B., Khader, Yousef Saleh, Koul, Parvaiz A., Khang, Young-Ho, Servan-Mori, Edson E., Goenka, Shifalika, Patten, Scott B., Farvid, Maryam S., Fischer, Florian, Benson, Jennifer, Blosser, Christopher D., Aichour, Amani Nidhal, Kalkonde, Yogeshwar, Wesana, Joshua, Steel, Nicholas, Alabed, Samer, Ärnlöv, Johan, Kawakami, Norito, Memish, Ziad A., Huang, John J., Abraha, Haftom Niguse, Fraser, Maya, Violante, Francesco S., Mruts, Kalayu Birhane, Tsilimparis, Nikolaos, O'Donnell, Martin J., Al Lami, Faris Hasan, Jürisson, Mikk, Mengistie, Mubarek Abera, Jakovljevic, Mihajlo B., Ebrahimi, Hedyeh, Sinha, Dhirendra Narain, Molla Assaye, Ashagre, Mohammed, Shafiu, Ma, Stefan, Friedman, Joseph, Goulart, Alessandra Carvalho, Lyons, Ronan A., Sawhney, Monika, Bello, Aminu K., Chitheer, Abdulaal A., Gupta, Rahul, Bikbov, Boris, Havmoeller, Rasmus, Antonio, Carl Abelardo T., Yoon, Seok-Jun, Alhabib, Samia, Alene, Kefyalew Addis, Dey, Subhojit, Yaseri, Mehdi, Olusanya, Bolajoko Olubukunola, El Sayed Zaki, Maysaa, Avokpaho, Euripide Frinel G. Arthur, Nyakarahuka, Luke, Postma, Maarten J., Shi, Peilin, Aiyar, Sneha, Pacella, Rosana E., Hankey, Graeme J., Sykes, Bryan L., Kengne, Andre Pascal, Magis-Rodriguez, Carlos, Mayosi, Bongani M., Lopez, Alan D., Kasaeian, Amir, Handal, Alexis J., Ukwaja, Kingsley Nnanna, Eshetie, Setegn, Shamsizadeh, Morteza, Mueller, Ulrich O., Tortajada, Miguel, Schutte, Aletta E., Christopher, Devasahayam Jesudas, Szoeke, Cassandra E.I., Mishra, Shiva Raj, Breitborde, Nicholas J.K., Abera, Semaw Ferede, Bizuayehu, Habtamu Mellie, Gamkrelidze, Amiran, Car, Mate, Sahraian, Mohammad Ali, Diaz-Torné, Cesar, Hakuzimana, Alex, Shrime, Mark G., Taveira, Nuno, Trujillo, Ulises, Sobngwi, Eugene, Khalil, Ibrahim A., Béjot, Yannick, Tonelli, Marcello, Christensen, Hanne, Truelsen, Thomas, Morawska, Lidia, Kim, Sungroul, Ray, Sarah E., Tandon, Nikhil, Kuate Defo, Barthelemy, Kimokoti, Ruth W., Mikesell, Joseph, Oladimeji, Olanrewaju, Muller, Kate, Jin, Ye, Ammar, Walid, Jayatilleke, Achala Upendra, Colquhoun, Samantha M., Altirkawi, Khalid A., Crump, John A., Hu, Guoqing, Roy, Ambuj, Abbas, Kaja M., Tyrovolas, Stefanos, Catalá-López, Ferrán, Wakayo, Tolassa, Shaikh, Masood Ali, Temsah, Mohamad-Hani, Huang, Hsiang, Kazanjan, Konstantin, Norheim, Ole F., Kinfu, Yohannes, Gakidou, Emmanuela, He, Fei, Bekele, Bayu Begashaw, Feyissa, Tesfaye Regassa, Srinivasan, Vinay, Enayati, Ahmadali, Memiah, Peter, Pigott, David M., Atre, Sachin R., Ogbo, Felix Akpojene, Weiderpass, Elisabete, Chen, Honglei, Cohen, Aaron J., Parsaeian, Mahboubeh, Liu, Shiwei, and She, Jun
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1. No poverty ,3. Good health - Abstract
BACKGROUND: Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respect to development status can identify exemplars for best practice. To accomplish this, the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) estimated age-specific and sex-specific all-cause mortality between 1970 and 2016 for 195 countries and territories and at the subnational level for the five countries with a population greater than 200 million in 2016. METHODS: We have evaluated how well civil registration systems captured deaths using a set of demographic methods called death distribution methods for adults and from consideration of survey and census data for children younger than 5 years. We generated an overall assessment of completeness of registration of deaths by dividing registered deaths in each location-year by our estimate of all-age deaths generated from our overall estimation process. For 163 locations, including subnational units in countries with a population greater than 200 million with complete vital registration (VR) systems, our estimates were largely driven by the observed data, with corrections for small fluctuations in numbers and estimation for recent years where there were lags in data reporting (lags were variable by location, generally between 1 year and 6 years). For other locations, we took advantage of different data sources available to measure under-5 mortality rates (U5MR) using complete birth histories, summary birth histories, and incomplete VR with adjustments; we measured adult mortality rate (the probability of death in individuals aged 15-60 years) using adjusted incomplete VR, sibling histories, and household death recall. We used the U5MR and adult mortality rate, together with crude death rate due to HIV in the GBD model life table system, to estimate age-specific and sex-specific death rates for each location-year. Using various international databases, we identified fatal discontinuities, which we defined as increases in the death rate of more than one death per million, resulting from conflict and terrorism, natural disasters, major transport or technological accidents, and a subset of epidemic infectious diseases; these were added to estimates in the relevant years. In 47 countries with an identified peak adult prevalence for HIV/AIDS of more than 0·5% and where VR systems were less than 65% complete, we informed our estimates of age-sex-specific mortality using the Estimation and Projection Package (EPP)-Spectrum model fitted to national HIV/AIDS prevalence surveys and antenatal clinic serosurveillance systems. We estimated stillbirths, early neonatal, late neonatal, and childhood mortality using both survey and VR data in spatiotemporal Gaussian process regression models. We estimated abridged life tables for all location-years using age-specific death rates. We grouped locations into development quintiles based on the Socio-demographic Index (SDI) and analysed mortality trends by quintile. Using spline regression, we estimated the expected mortality rate for each age-sex group as a function of SDI. We identified countries with higher life expectancy than expected by comparing observed life expectancy to anticipated life expectancy on the basis of development status alone. FINDINGS: Completeness in the registration of deaths increased from 28% in 1970 to a peak of 45% in 2013; completeness was lower after 2013 because of lags in reporting. Total deaths in children younger than 5 years decreased from 1970 to 2016, and slower decreases occurred at ages 5-24 years. By contrast, numbers of adult deaths increased in each 5-year age bracket above the age of 25 years. The distribution of annualised rates of change in age-specific mortality rate differed over the period 2000 to 2016 compared with earlier decades: increasing annualised rates of change were less frequent, although rising annualised rates of change still occurred in some locations, particularly for adolescent and younger adult age groups. Rates of stillbirths and under-5 mortality both decreased globally from 1970. Evidence for global convergence of death rates was mixed; although the absolute difference between age-standardised death rates narrowed between countries at the lowest and highest levels of SDI, the ratio of these death rates-a measure of relative inequality-increased slightly. There was a strong shift between 1970 and 2016 toward higher life expectancy, most noticeably at higher levels of SDI. Among countries with populations greater than 1 million in 2016, life expectancy at birth was highest for women in Japan, at 86·9 years (95% UI 86·7-87·2), and for men in Singapore, at 81·3 years (78·8-83·7) in 2016. Male life expectancy was generally lower than female life expectancy between 1970 and 2016, and
42. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
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Hay, Simon I, Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbas, Kaja M, Abd-Allah, Foad, Abdulle, Abdishakur M, Abebo, Teshome Abuka, Abera, Semaw Ferede, Aboyans, Victor, Abu-Raddad, Laith J, Ackerman, Ilana N, Adedeji, Isaac A, Adetokunboh, Olatunji, Afshin, Ashkan, Aggarwal, Rakesh, Agrawal, Sutapa, Agrawal, Anurag, Kiadaliri, Aliasghar Ahmad, Ahmed, Muktar Beshir, Aichour, Amani Nidhal, Aichour, Ibtihel, Aichour, Miloud Taki Eddine, Aiyar, Sneha, Akinyemiju, Tomi F, Akseer, Nadia, Al Lami, Faris Hasan, Alahdab, Fares, Al-Aly, Ziyad, Alam, Khurshid, Alam, Noore, Alam, Tahiya, Alasfoor, Deena, Alene, Kefyalew Addis, Ali, Raghib, Alizadeh-Navaei, Reza, Alkaabi, Juma M, Alkerwi, Ala'a, Alla, Francois, Allebeck, Peter, Allen, Christine, Al-Maskari, Fatma, AlMazroa, Mohammad AbdulAziz, Al-Raddadi, Rajaa, Alsharif, Ubai, Alsowaidi, Shirina, Althouse, Benjamin M, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amini, Erfan, Ammar, Walid, Ampem, Yaw Amoako, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Anwari, Palwasha, Arnlov, Johan, Arora, Megha, Artaman, Al, Aryal, Krishna Kumar, Asgedom, Solomon W, Atey, Tesfay Mehari, Atnafu, Niguse Tadele, Avila-Burgos, Leticia, Avokpaho, Euripide Frinel G Arthur, Awasthi, Ashish, Awasthi, Shally, Quintanilla, Beatriz Paulina Ayala, Azarpazhooh, Mahmoud Reza, Azzopardi, Peter, Babalola, Tesleem Kayode, Bacha, Umar, Badawi, Alaa, Balakrishnan, Kalpana, Bannick, Marlena S, Barac, Aleksandra, Barker-Collo, Suzanne L, Barnighausen, Till, Barquera, Simon, Barrero, Lope H, Basu, Sanjay, Battista, Robert, Battle, Katherine E, Baune, Bernhard T, Bazargan-Hejazi, Shahrzad, Beardsley, Justin, Bedi, Neeraj, Bejot, Yannick, Bekele, Bayu Begashaw, Bell, Michelle L, Bennett, Derrick A, Bennett, James R, Bensenor, Isabela M, Benson, Jennifer, Berhane, Adugnaw, Berhe, Derbew Fikadu, Bernabe, Eduardo, Betsu, Balem Demtsu, Beuran, Mircea, Beyene, Addisu Shunu, Bhansali, Anil, Bhatt, Samir, Bhutta, Zulfiqar A, Biadgilign, Sibhatu, Bienhoff, Kelly, Bikbov, Boris, Birungi, Charles, Biryukov, Stan, Bisanzio, Donal, Bizuayehu, Habtamu Mellie, Blyth, Fiona M, Boneya, Dube Jara, Bose, Dipan, Bou-Orm, Ibrahim R, Bourne, Rupert RA, Brainin, Michael, Brayne, Carol EG, Brazinova, Alexandra, Breitborde, Nicholas JK, Briant, Paul S, Britton, Gabrielle, Brugha, Traolach S, Buchbinder, Rachelle, Bulto, Lemma Negesa Bulto, Bumgarner, Blair, Butt, Zahid A, Cahuana-Hurtado, Lucero, Cameron, Ewan, Ricardo Campos-Nonato, Ismael, Carabin, Helene, Cardenas, Rosario, Carpenter, David O, Carrero, Juan Jesus, Carter, Austin, Carvalho, Felix, Casey, Daniel, Castaneda-Orjuela, Carlos A, Rivas, Jacqueline Castillo, Castle, Chris D, Catala-Lopez, Ferran, Chang, Jung-Chen, Charlson, Fiona J, Chaturvedi, Pankaj, Chen, Honglei, Chibalabala, Mirriam, Chibueze, Chioma Ezinne, Chisumpa, Vesper Hichilombwe, Chitheer, Abdulaal A, Chowdhury, Rajiv, Christopher, Devasahayam Jesudas, Ciobanu, Liliana G, Cirillo, Massimo, Colombara, Danny, Cooper, Leslie Trumbull, Cooper, Cyrus, Cortesi, Paolo Angelo, Cortinovis, Monica, Criqui, Michael H, Cromwell, Elizabeth A, Cross, Marita, Crump, John A, Dadi, Abel Fekadu, Dalal, Koustuv, Damasceno, Albertino, Dandona, Lalit, Dandona, Rakhi, Das Neves, Jose, Davitoiu, Dragos V, Davletov, Kairat, De Courten, Barbora, De Leo, Diego, De Steur, Hans, Degenhardt, Louisa, Deiparine, Selina, Dellavalle, Robert P, Deribe, Kebede, Deribew, Amare, Des Jarlais, Don C, Dey, Subhojit, Dharmaratne, Samath D, Dhillon, Preet K, Dicker, Daniel, Djalalinia, Shirin, Do, Huyen Phuc, Dokova, Klara, Doku, David Teye, Dorsey, E Ray, Bender Dos Santos, Kadine Priscila, Driscoll, Tim R, Dubey, Manisha, Duncan, Bruce Bartholow, Ebel, Beth E, Echko, Michelle, El-Khatib, Ziad Ziad, Enayati, Ahmadali, Endries, Aman Yesuf, Ermakov, Sergey Petrovich, Erskine, Holly E, Eshetie, Setegn, Eshrati, Babak, Esteghamati, Alireza, Estep, Kara, Fanuel, Fanuel Belayneh Bekele, Farag, Tamer, Sofia, Carla, 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Nicholas, Gugnani, Harish Chander, Gupta, Rajeev, Gupta, Prakash C, Gupta, Tanush, Gupta, Vipin, Gupta, Rahul, Gutierrez, Reyna A, Hachinski, Vladimir, Hafezi-Nejad, Nima, Hailu, Alemayehu Desalegne, Hailu, Gessessew Bugssa, Hamadeh, Randah Ribhi, Hamidi, Samer, Hammami, Mouhanad, Handal, Alexis J, Hankey, Graeme J, Hao, Yuantao, Harb, Hilda L, Hareri, Habtamu Abera, Haro, Josep Maria, Harun, Kimani M, Harvey, James, Hassanvand, Mohammad Sadegh, Havmoeller, Rasmus, Hay, Roderick J, Hedayati, Mohammad T, Hendrie, Delia, Henry, Nathaniel J, Heredia-Pi, Ileana Beatriz, Heydarpour, Pouria, Hoek, Hans W, Hoffman, Howard J, Horino, Masako, Horita, Nobuyuki, Hosgood, H Dean, Hostiuc, Sorin, Hotez, Peter J, Hoy, Damian G, Htet, Aung Soe, Hu, Guoqing, Huang, John J, Huynh, Chantal, Iburg, Kim Moesgaard, Igumbor, Ehimario Uche, Ikeda, Chad, Irvine, Caleb Mackay Salpeter, Jacobsen, Kathryn H, Jahanmehr, Nader, Jakovljevic, Mihajlo B, James, Peter, Jassal, Simerjot K, Javanbakht, Mehdi, Jayaraman, 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Deborah Carvalho, Mamun, Abdullah A, Manguerra, Helena, Manhertz, Treh, Mantovani, Lorenzo G, Mapoma, Chabila C, March, Lyn M, Marczak, Laurie B, Martinez-Raga, Jose, Henrique, Paulo, Martins, Viegas, Martins-Melo, Francisco Rogerlndio, Martopullo, Ira, Marz, Winfried, Mathur, Manu Raj, Mazidi, Mohsen, McAlinden, Colm, McGaughey, Madeline, McGrath, John J, Mckee, Martin, Mehata, Suresh, Meier, Toni, Meles, Kidanu Gebremariam, Memiah, Peter, Memish, Ziad A, Mendoza, Walter, Mengesha, Melkamu Merid, Mengistie, Mubarek Abera, Mengistu, Desalegn Tadese, Mensah, George A, Meretoja, Atte, Meretoja, Tuomo J, Mezgebe, Haftay Berhane, Micha, Renata, Millear, Anoushka, Miller, Ted R, Minnig, Shawn, Mirarefin, Mojde, Mirrakhimov, Erkin M, Misganaw, Awoke, Mishra, Shiva Raj, Mitchell, Philip B, Mohammad, Karzan Abdulmuhsin, Mohammadi, Alireza, Mohammed, Shafiu, Mohammed, Kedir Endris, Mohammed, Muktar Sano Kedir, Mohan, Murali BV, Mokdad, Ali H, Mollenkopf, Sarah K, Monasta, Lorenzo, Montanez 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Zoubida, Zaki, Maysaa El Sayed, Zegeye, Elias Asfaw, Zenebe, Zerihun Menlkalew, Zhang, Xueying, Zheng, Yingfeng, Zhou, Maigeng, Zipkin, Ben, Zodpey, Sanjay, Zoeckler, Leo, Zuhlke, Liesl Joanna, Murray, Christopher JL, and Collaborators, GBD DALYs HALE
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Adult ,Aged, 80 and over ,Male ,1. No poverty ,Middle Aged ,Global Health ,Communicable Diseases ,3. Good health ,Global Burden of Disease ,Age Distribution ,Life Expectancy ,Residence Characteristics ,Cause of Death ,Humans ,Wounds and Injuries ,Disabled Persons ,Female ,sense organs ,Quality-Adjusted Life Years ,Sex Distribution ,Noncommunicable Diseases ,Aged - Abstract
Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures to monitor such changes in population health: disability-adjusted life-years (DALYs) and healthy life expectancy (HALE). We used these measures to track trends and benchmark progress compared with expected trends on the basis of the Socio-demographic Index (SDI).
43. Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017
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8. Economic growth ,1. No poverty ,10. No inequality ,3. Good health
44. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
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Nguyen, Grant, Alahdab, Fares, Yu, Chuanhua, Jassal, Simerjot K., Mori, Rintaro, Sylte, Dillon, Foreman, Kyle J., Hankey, Graeme J., Goenka, Shifalika, Ngunjiri, Josephine Wanjiku, Li, Yichong, Olsen, Helen E., Poulton, Richie G., Mueller, Ulrich O., Truelsen, Thomas, Okoro, Anselm, Jayaraman, Sudha P., Sawhney, Monika, Nasher, Jamal T., Driscoll, Tim R., Lucas, Timothy C. D., Bulto, Lemma Negesa Bulto, Kassebaum, Nicholas J., Murdoch, Ray, Sarah E., Berhane, Adugnaw, Millear, Anoushka, Soljak, Michael, Ronfani, Luca, Karam, Nadim E., Kim, Daniel, Takala, Jukka S., Linn, Shai, Smith, David L., Bikbov, Boris, Pinho, Christine, Amare, Azmeraw T., Asgedom, Solomon W., Reitsma, Marissa, Mokdad, Ali H., Montico, Marcella, Nichols, Emma, Harb, Hilda L., Chitheer, Abdulaal A., Schutte, Aletta E., Tanne, David, Frostad, Joseph J., Fischer, Florian, Majdan, Marek, Gebre, Teshome, Newton, Charles R., Mathur, Manu Raj, Hofman, Howard J., Mendoza, Walter, Silveira, Dayane Gabriele Alves, Srinivasan, Vinay, Negasa, Dumessa Edessa, Werdecker, Andrea, Ahmed, Muktar Beshir, Kokubo, Yoshihiro, Berhe, Derbew Fikadu, Lotufo, Paulo A., Mengesha, Melkamu Merid, Rahimi-Movaghar, Afarin, Tobollik, Myriam, Leshargie, Cheru Tesema, Sartorius, Benn, Pacella, Rosana E., Atey, Tesfay Mehari, Yoon, Seok-Jun, Fazeli, Mir Sohail, Béjot, Yannick, Moses, Mark, Aggarwal, Rakesh, Heredia-Pi, Ileana Beatriz, Birungi, Charles, Nguyen, Quyen Le, Rao, Paturi Vishnupriya, Silva, Diego Augusto Santos, Geleto, Ayele, Leigh, James, Kisa, Adnan, Dharmaratne, Samath D., Ningrum, Dina Nur Anggraini, Phillips, Michael Robert, Haro, Josep Maria, Stein, Dan J., Montañez Hernandez, Julio Cesar, Zipkin, Ben, Pletcher, Martin A., Rahman, Muhammad Aziz, Leung, Janni, Thrift, Amanda G., Battista, Robert, Liang, Xiaofeng, Singh, Jasvinder A., Osgood-Zimmerman, Aaron, Sahathevan, Ramesh, Amini, Erfan, Rojas-Rueda, David, Abera, Semaw Ferede, Rahimi-Movaghar, Vafa, Moradi-Lakeh, Maziar, Huynh, Chantal, Nachega, Jean B., Martins-Melo, Francisco Rogerlândio, Williams, Hywel C., Uthman, Olalekan A., Pandian, Jeyaraj D., Bannick, Marlena S., Artaman, Al, Liu, Yang, Rothenbacher, Dietrich, Arora, Megha, Ciobanu, Liliana G., Ortiz, Alberto, Kesavachandran, Chandrasekharan Nair, Papachristou, Christina, El-Khatib, Ziad Ziad, Rubagotti, Enrico, Santos, Itamar S., Flaxman, Abraham D., Naidoo, Kovin S., Panda, Basant Kumar, Kopec, Jacek A., Rankin, Zane, Aryal, Krishna Kumar, Oren, Eyal, Petzold, Max, Djalalinia, Shirin, Murthy, Gudlavalleti Venkata Satyanarayana, Brugha, Traolach S., Dandona, Lalit, Bryane, Al-Raddadi, Rajaa, Cooper, Leslie Trumbull, Hareri, Habtamu Abera, Zheng, Yingfeng, Dokova, Klara, Murthy, Srinivas, Johnson, Catherine O., Reinig, Nikolas, Lee, Paul H., Ginawi, Ibrahim Abdelmageem Mohamed, Patil, Snehal T., Godwin, William W., Vijayakumar, Lakshmi, Smith, Mari, Enayati, Ahmadali, Stanaway, Jefrey D., Hendrie, Delia, Mehata, Suresh, Tymeson, Hayley, Azzopardi, Peter, Ribeiro, Antonio L., Rajsic, Sasa, John, Denny, Cortesi, Paolo Angelo, Biryukov, Stan, Alam, Tahiya, Opio, John Nelson, Alam, Khurshid, Katikireddi, Srinivasa Vittal, Safri, Saeid, Kahsay, Amaha, Christopher, Devasahayam Jesudas, Majdzadeh, Reza, Alam, Noore, Yihdego, Mahari Gidey, Gupta, Tanush, March, Lyn M., Mensah, George A., Handal, Alexis J., Hotez, Peter J., Abajobir, Amanuel Alemu, Gugnani, Harish Chander, Sepanlou, Sadaf G., Wadilo, Fiseha, Hassanvand, Mohammad Sadegh, Rabiee, Rynaz H. S., Bekele, Bayu Begashaw, Kumar, Pushpendra, Hoy, Damian G., Ammar, Walid, Baune, Bernhard T., Szoeke, Cassandra E. 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A., Kivimaki, Mika, Kengne, Andre Pascal, Benson, Jennifer, Briant, Paul S., Woodbrook, Rachel, Woolf, Anthony D., Alene, Kefyalew Addis, Fernandes, João C., Do, Huyen Phuc, Xavier, Denis, Agrawal, Sutapa, Ukwaja, Kingsley Nnanna, Uzochukwu, Benjamin S. Chudi, Kasaeian, Amir, Pearce, Neil, Rahman, Mahfuzar, Weiss, Daniel J., Satpathy, Maheswar, Lorkowski, Stefan, Purwar, Manorama, Lim, Stephen S., Alkerwi, Ala'a, Noubiap, Jean Jacques N., Taveira, Nuno, Chibueze, Chioma Ezinne, Zodpey, Sanjay, Shariful Islam, Sheikh Mohammed, Gopalani, Sameer Vali, Tegegne, Teketo Kassaw, Vos, Theo, Zenebe, Zerihun Menlkalew, Quintanilla, Beatriz Paulina Ayala, Miller, Ted R., Kim, Yun Jin, Al Lami, Faris Hasan, Hailu, Gessessew Bugssa, Hao, Yuantao, Sanchez-Niño, Maria Dolores, Barquera, Simon, Jiang, Guohong, Shaikh, Masood Ali, Martins, Paulo Henrique Viegas, Salomon, Joshua A., Skirbekk, Vegard, Vollset, Stein Emil, Lodha, Rakesh, Hay, Simon I., Yano, Yuichiro, Sharma, Jayendra, Krohn, Kristopher J., Qorbani, Mostafa, Jürisson, Mikk, Roy, Ambuj, Mahdavi, Mahdi, Shi, Peilin, Ansha, Mustafa Geleto, Mohammad, Karzan Abdulmuhsin, Brainin, Michael, Estep, Kara, Rahimi, Kazem, Bennett, James R., Fürst, Thomas, Lunevicius, Raimundas, Lyons, Ronan A., Terkawi, Abdullah Sulieman, Hachinski, Vladimir, Swaminathan, Soumya, Farzadfar, Farshad, Mazidi, Mohsen, Micha, Renata, Mohammed, Shafu, Gishu, Melkamu Dedefo, Stokes, Mark Andrew, Tortajada, Miguel, Updike, Rachel, Piradov, Michael A., Lalloo, Ratilal, Gething, Peter W., Yan, Lijing L., Olusanya, Jacob Olusegun, Shiferaw, Mekonnen Sisay, Roshandel, Gholamreza, Mantovani, Lorenzo G., Franklin, Richard C., Aiyar, Sneha, Goel, Kashish, Mohammed, Muktar Sano Kedir, Yotebieng, Marcel, Knudsen, Ann Kristin, Yonemoto, Naohiro, Prasad, Narayan, Bell, Michelle L., Olagunju, Tinuke Oluwasefunmi, Shields, Chloe, Magdy Abd El Razek, Mohammed, Shaheen, Amira, Ermakov, Sergey Petrovich, Maddison, Emilie R., Seedat, Soraya, Manguerra, Helena, McKee, Martin, Pa, Mahesh, De Steur, Hans, Htet, Aung Soe, Resnikof, Serge, Ackerman, Ilana N., Thomas, Katie E., Shirude, Shreya, Hafezi-Nejad, Nima, Pesudovs, Konrad, Thompson, Robert, Dalal, Koustuv, Zoeckler, Leo, Levi, Miriam, Cameron, Ewan, Britton, Gabrielle, Cirillo, Massimo, Skiadaresi, Eirini, Olusanya, Bolajoko Olubukunola, Topor-Madry, Roman, Sousa, Tatiane Cristina Moraes, Kamal, Ritul, Touvier, Mathilde, Kinfu, Yohannes, Pereira, David M., Renzaho, Andre M. N., Strub, Bryan, Gakidou, Emmanuela, Schneider, Ione J. C., Gupta, Prakash C., Popova, Svetlana, Bisanzio, Donal, Javanbakht, Mehdi, O'Donnell, Martin J., Varughese, Santosh, Vasankari, Tommi, Gebregergs, Gebremedhin Berhe, Nangia, Vinay, Alvis-Guzman, Nelson, Das Neves, José, Goodridge, Amador, Patten, Scott B., Bose, Dipan, Mirrakhimov, Erkin M., Saadat, Soheil, Duncan, Bruce Bartholow, Zhou, Maigeng, Uneke, Chigozie Jesse, Macarayan, Erlyn Rachelle King, Alsharif, Ubai, Heydarpour, Pouria, Tarekegn, Yihunie L., Rao, Puja C., Perez, Krystle Marie, Bumgarner, Blair, Aichour, Amani Nidhal, Oh, In-Hwan, Goto, Atsushi, Memiah, Peter, Alsowaidi, Shirina, Tadakamadla, Santosh Kumar, Dorsey, E. Ray, Park, Eun-Kee, Almazroa, Mohammad Abdulaziz, Pillay, Julian David, Weiderpass, Elisabete, Goldberg, Ellen M., Kosen, Soewarta, Fitzmaurice, Christina, Westerman, Ronny, Gupta, Rahul, Tobe-Gai, Ruoyan, Adedeji, Isaac A., Liu, Shiwei, Patton, George C., Parsaeian, Mahboubeh, Younis, Mustafa Z., Safdarian, Mahdi, Balakrishnan, Kalpana, Singh, Om Prakash, Misganaw, Awoke, Crump, John A., Awasthi, Shally, Alizadeh-Navaei, Reza, Tandon, Nikhil, Breitborde, Nicholas J. K., Agrawal, Anurag, Brayne, Carol E. G., Peterson, Carrie Beth, Cooper, Cyrus, Khubchandani, Jagdish, Gupta, Vipin, Kravchenko, Michael, Mollenkopf, Sarah K., Looker, Katharine J., Negoi, Ruxandra Irina, Feigin, Valery L., Abdulkader, Rizwan Suliankatchi, Negoi, Ionut, Silva, João Pedro, Mamun, Abdullah A., Jha, Vivekanand, Fanuel, Fanuel Belayneh Bekele, She, Jun, Casey, Daniel, Manhertz, Treh, Abebo, Teshome Abuka, Musa, Kamarul Imran, Lallukka, Tea, Shishani, Kawkab, Osborne, Richard H., Altirkawi, Khalid A., Alkaabi, Juma M., Eshrati, Babak, Anwari, Palwasha, Zaidi, Zoubida, Zegeye, Elias Asfaw, Davletov, Kairat, Vladimirov, Sergey K., Hailu, Alemayehu Desalegne, Sinha, Dhirendra Narain, Ali, Raghib, Santric Milicevic, Milena M., Alla, François, Fereshtehnejad, Seyed-Mohammad, Chibalabala, Mirriam, Betsu, Balem Demtsu, Feigl, Andrea B., Stovner, Lars Jacob, Bhutta, Zulfqar A., Reiner, Robert C., Bicer, Burcu Kucuk, Purcell, Carrie, Bienhof, Kelly, Colombara, Danny, Mitchell, Philip B., Kissoon, Niranjan, Davitoiu, Dragos V., Khader, Yousef Saleh, Lansingh, Van C., Farag, Tamer, Mengistie, Mubarek Abera, Goulart, Alessandra Carvalho, Feyissa, Tesfaye Regassa, Liu, Angela, Fullman, Nancy, Azarpazhooh, Mahmoud Reza, Paulson, Katherine, Perico, Norberto, Alasfoor, Deena, Lozano, Rafael, Buchbinder, Rachelle, Ye, Pengpeng, Shoman, Haitham, Abbafati, Cristiana, Babalola, Tesleem Kayode, Gebrehiwot, Tsegaye Tewelde, De Leo, Diego, Beyene, Addisu Shunu, Taylor, Hugh R., Prabhakaran, Dorairaj, Meles, Kidanu Gebremariam, Carvalho, Felix, Yimam, Hassen Hamid, Moraga, Paula, Bernabé, Eduardo, Aboyans, Victor, Esteghamati, Alireza, Cortinovis, Monica, Harvey, James, Van Boven, Job F. M., Nguyen, Cuong Tat, Norrving, Bo, Leasher, Janet L., Silberberg, Donald H., Butt, Zahid A., Salama, Joseph, Larsson, Anders, Troeger, Christopher, Keren, Andre, Morrison, Shane D., Venketasubramanian, Narayanaswamy, McAlinden, Colm, Bärnighausen, Till, Jahanmehr, Nader, Chaturvedi, Pankaj, Yip, Paul, Sagar, Rajesh, Abbas, Kaja M., Tonelli, Marcello, Kiadaliri, Aliasghar Ahmad, Magdy Abd El Razek, Hassan, Atnafu, Niguse Tadele, Whiteford, Harvey A., Theis, Andrew M., Hostiuc, Sorin, Barrero, Lope H., Koyanagi, Ai, Koul, Parvaiz A., Wallin, Mitchell T., Naheed, Aliya, Carpenter, David O., Campos-Nonato, Ismael Ricardo, Doku, David Teye, Hamadeh, Randah Ribhi, Malekzadeh, Reza, Furtado, Joao M., Cahuana-Hurtado, Lucero, Undurraga, Eduardo A., Thamsuwan, Ornwipa, Martopullo, Ira, Bou-Orm, Ibrahim R., Biadgilign, Sibhatu, Workicho, Abdulhalik, Malhotra, Rajesh, Futran, Neal D., Boneya, Dube Jara, Mezgebe, Haftay Berhane, Mishra, Shiva Raj, Ranabhat, Chhabi Lal, Charlson, Fiona J., Thomas, Nihal, Temam Shifa, Girma, Deribe, Kebede, Norheim, Ole F., Althouse, Benjamin M., Pourmalek, Farshad, Hosgood, H. Dean, Venkatesh, Steinke, Sabine, Nguyen, Minh, Al-Maskari, Fatma, Khosravi, Ardeshir, Petri, William Arthur, Ram, Usha, Akseer, Nadia, Harun, Kimani M., Abate, Kalkidan Hassen, Radfar, Amir, Abdulle, Abdishakur M., Jeemon, Panniyammakal, Kassaw, Nigussie Assefa, Ogbo, Felix Akpojene, Hoek, Hans W., Mohammadi, Alireza, Bhansali, Anil, Deiparine, Selina, Geleijnse, Johanna M., Nyandwi, Alypio, Marczak, Laurie B., Kumar, G. Anil, Samy, Abdallah M., Dubey, Manisha, Roth, Gregory A., Minnig, Shawn, Monasta, Lorenzo, Kyu, Hmwe H., Bizuayehu, Habtamu Mellie, Rivas, Jacqueline Castillo, Gupta, Rajeev, Cross, Marita, Bennett, Derrick A., Ong, Kanyin, Rawaf, Salman, Meretoja, Atte, Awasthi, Ashish, Khang, Young-Ho, Irvine, Caleb Mackay Salpeter, Shigematsu, Mika, Hu, Guoqing, Mountjoy-Venning, Clif, Tehrani-Banihashemi, Arash, Rokni, Mohammad Bagher, Lambert, Nkurunziza, Weintraub, Robert G., Tesssema, Belay, Khalil, Ibrahim A., Filip, Irina, Tafere, Getachew Redae, Sposato, Luciano A., Horita, Nobuyuki, Bhatt, Samir, Martinez-Raga, Jose, Osman, Majdi, Ebel, Beth E., Schwebel, David C., Chowdhury, Rajiv, Santos, João Vasco, Robinson, Stephen R., Mapoma, Chabila C., Meretoja, Tuomo J., Abd-Allah, Foad, Vlassov, Vasiliy Victorovich, Gemechu, Bikila Lencha, Allebeck, Peter, Kimokoti, Ruth W., Dicker, Daniel, Beuran, Mircea, Nguyen, Trang Huyen, Yaghoubi, Mohsen, Kar, Chittaranjan, Rafay, Anwar, Hammami, Mouhanad, Castle, Chris D., Gotay, Carolyn C., Steiner, Caitlyn, Sunguya, Bruno F., Gona, Philimon N., Slepak, Erica Leigh, Dey, Subhojit, Bourne, Rupert R. A., Tyrovolas, Stefanos, Jensen, Paul N., Echko, Michelle, Leung, Ricky, McGaughey, Madeline, Endries, Aman Yesuf, McGrath, John J., Carabin, Hélène, Magis-Rodriguez, Carlos, Blyth, Fiona M., Havmoeller, Rasmus, Amoako, Yaw Ampem, Natarajan, Gopalakrishnan, Ikeda, Chad, Sufyan, Muawiyyah Babale, Johnson, Sarah Charlotte, Bensenor, Isabela M., Catalá-López, Ferrán, Afshin, Ashkan, Akinyemiju, Tomi F., Keiyoro, Peter Njenga, Sobngwi, Eugene, Karch, André, Aichour, Miloud Taki Eddine, Hamidi, Samer, Yadgir, Simon, Wang, Yuan-Pang, Kaul, Anil, Zhang, Xueying, Oladimeji, Olanrewaju, Mengistu, Desalegn Tadese, Brazinova, Alexandra, Weichenthal, Scott, Kadel, Rajendra, Gillum, Richard F., Huang, John J., Defo, Barthelemy Kuate, Schöttker, Ben, Rahman, Mohammad Hifz Ur, Criqui, Michael H., Wakayo, Tolassa, Liben, Misgan Legesse, Meier, Toni, Kawakami, Norito, Salvi, Sundeep Santosh, Tuzcu, Emin Murat, Mohammed, Kedir Endris, Lan, Qing, Memish, Ziad A., Bedi, Neeraj, Erskine, Holly E., Theadom, Alice M., Dellavalle, Robert P., Gesesew, Hailay Abrha, Deribew, Amare, Murray, Christopher J. L., Dadi, Abel Fekadu, Zuhlke, Liesl Joanna, Sanabria, Juan Ramon, Sykes, Bryan L., Saxena, Sonia, Sreeramareddy, Chandrashekhar T., Dos Santos, Kadine Priscila Bender, Schmidt, Maria Inês, Malta, Deborah Carvalho, Remuzzi, Giuseppe, Shirkoohi, Reza, Eshetie, Setegn, Tran, Bach Xuan, Singh, Narinder Pal, Parry, Charles D., Logroscino, Giancarlo, Tabarés-Seisdedos, Rafael, Yakob, Bereket, Giussani, Giorgia, Karimi, Seyed M., Sur, Patrick J., Obermeyer, Carla Makhlouf, Rezaei, Satar, Hedayati, Mohammad T., James, Peter, Chang, Jung-Chen, Liu, Patrick Y., Ghajar, Alireza, Jonas, Jost B., Carter, Austin, Badawi, Alaa, Sorensen, Reed J. D., Kabir, Zubair, Ferrari, Alize J., Steel, Nicholas, Shibuya, Kenji, Wijeratne, Tissa, Xu, Gelin, Kassa, Getachew Mullu, Traebert, Jeferson, Barac, Aleksandra, Kissimova-Skarbek, Katarzyna A., Ota, Erika, Stathopoulou, Vasiliki, Jakovljevic, Mihajlo B., Khoja, Abdullah T., Zaki, Maysaa El Sayed, Singh, Virendra, Barker-Collo, Suzanne L., Gutiérrez, Reyna A., Nong, Vuong Minh, Shamsipour, Mansour, März, Winfried, Rai, Rajesh Kumar, Horino, Masako, Paudel, Deepak, Veerman, Lennert J., Jacobsen, Kathryn H., Dandona, Rakhi, Sharma, Rajesh, and Santomauro, Damian
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1. No poverty ,3. Good health - Abstract
BACKGROUND: Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures to monitor such changes in population health: disability-adjusted life-years (DALYs) and healthy life expectancy (HALE). We used these measures to track trends and benchmark progress compared with expected trends on the basis of the Socio-demographic Index (SDI). METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 countries and territories from 1990 to 2016. We calculated DALYs by summing years of life lost and years of life lived with disability for each location, age group, sex, and year. We estimated HALE using age-specific death rates and years of life lived with disability per capita. We explored how DALYs and HALE differed from expected trends when compared with the SDI: the geometric mean of income per person, educational attainment in the population older than age 15 years, and total fertility rate. FINDINGS: The highest globally observed HALE at birth for both women and men was in Singapore, at 75·2 years (95% uncertainty interval 71·9-78·6) for females and 72·0 years (68·8-75·1) for males. The lowest for females was in the Central African Republic (45·6 years [42·0-49·5]) and for males was in Lesotho (41·5 years [39·0-44·0]). From 1990 to 2016, global HALE increased by an average of 6·24 years (5·97-6·48) for both sexes combined. Global HALE increased by 6·04 years (5·74-6·27) for males and 6·49 years (6·08-6·77) for females, whereas HALE at age 65 years increased by 1·78 years (1·61-1·93) for males and 1·96 years (1·69-2·13) for females. Total global DALYs remained largely unchanged from 1990 to 2016 (-2·3% [-5·9 to 0·9]), with decreases in communicable, maternal, neonatal, and nutritional (CMNN) disease DALYs offset by increased DALYs due to non-communicable diseases (NCDs). The exemplars, calculated as the five lowest ratios of observed to expected age-standardised DALY rates in 2016, were Nicaragua, Costa Rica, the Maldives, Peru, and Israel. The leading three causes of DALYs globally were ischaemic heart disease, cerebrovascular disease, and lower respiratory infections, comprising 16·1% of all DALYs. Total DALYs and age-standardised DALY rates due to most CMNN causes decreased from 1990 to 2016. Conversely, the total DALY burden rose for most NCDs; however, age-standardised DALY rates due to NCDs declined globally. INTERPRETATION: At a global level, DALYs and HALE continue to show improvements. At the same time, we observe that many populations are facing growing functional health loss. Rising SDI was associated with increases in cumulative years of life lived with disability and decreases in CMNN DALYs offset by increased NCD DALYs. Relative compression of morbidity highlights the importance of continued health interventions, which has changed in most locations in pace with the gross domestic product per person, education, and family planning. The analysis of DALYs and HALE and their relationship to SDI represents a robust framework with which to benchmark location-specific health performance. Country-specific drivers of disease burden, particularly for causes with higher-than-expected DALYs, should inform health policies, health system improvement initiatives, targeted prevention efforts, and development assistance for health, including financial and research investments for all countries, regardless of their level of sociodemographic development. The presence of countries that substantially outperform others suggests the need for increased scrutiny for proven examples of best practices, which can help to extend gains, whereas the presence of underperforming countries suggests the need for devotion of extra attention to health systems that need more robust support. FUNDING: Bill & Melinda Gates Foundation.
45. Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017
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Muktar Beshir, Aichour, Amani Nidhal, Aichour, Ibtihel, Aichour, Miloud Taki Eddine, Akanda, Ali S, Akbari, Mohammad Esmaeil, Akibu, Mohammed, Akinyemi, Rufus Olusola, Akinyemiju, Tomi, Akseer, Nadia, Alahdab, Fares, Al-Aly, Ziyad, Alam, Khurshid, Alebel, Animut, Aleman, Alicia V, Alene, Kefyalew Addis, Al-Eyadhy, Ayman, Ali, Raghib, Alijanzadeh, Mehran, Alizadeh-Navaei, Reza, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Alla, François, Allebeck, Peter, Allen, Christine A, Alonso, Jordi, Al-Raddadi, Rajaa M, Alsharif, Ubai, Altirkawi, Khalid, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amini, Erfan, Ammar, Walid, Amoako, Yaw Ampem, Anber, Nahla Hamed, Andrei, Catalina Liliana, Androudi, Sofia, Animut, Megbaru Debalkie, Anjomshoa, Mina, Anlay, Degefaye Zelalem, Ansari, Hossein, Ansariadi, Ansariadi, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Appiah, Seth Christopher Yaw, Aremu, Olatunde, Areri, Habtamu Abera, Ärnlöv, Johan, Arora, Megha, Artaman, Al, Aryal, Krishna K, Asadi-Lari, Mohsen, 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Segen Gebremeskel, Tavakkoli, Mohammad, Taveira, Nuno, Tawye, Nega Yimer, Tehrani-Banihashemi, Arash, Tekalign, Tigist Gashaw, Tekle, Merhawi Gebremedhin, Temesgen, Habtamu, Temsah, Mohamad-Hani, Temsah, Omar, Terkawi, Abdullah Sulieman, Teshale, Manaye Yihune, Tessema, Belay, Teweldemedhin, Mebrahtu, Thakur, Jarnail Singh, Thankappan, Kavumpurathu Raman, Thirunavukkarasu, Sathish, Thomas, Laura Anne, Thomas, Nihal, Thrift, Amanda G, Tilahun, Binyam, To, Quyen G, Tobe-Gai, Ruoyan, Tonelli, Marcello, Topor-Madry, Roman, Topouzis, Fotis, Torre, Anna E, Tortajada-Girbés, Miguel, Tovani-Palone, Marcos Roberto, Towbin, Jeffrey A, Tran, Bach Xuan, Tran, Khanh Bao, Tripathi, Suryakant, Tripathy, Srikanth Prasad, Truelsen, Thomas Clement, Truong, Nu Thi, Tsadik, Afewerki Gebremeskel, Tsilimparis, Nikolaos, Tudor Car, Lorainne, Tuzcu, E Murat, Tyrovolas, Stefanos, Ukwaja, Kingsley Nnanna, Ullah, Irfan, Usman, Muhammad Shariq, Uthman, Olalekan A, Uzun, Selen Begüm, Vaduganathan, Muthiah, Vaezi, Afsane, Vaidya, Gaurang, Valdez, Pascual R, Varavikova, Elena, Varughese, Santosh, Vasankari, Tommi Juhani, Vasconcelos, Ana Maria Nogales, Venketasubramanian, Narayanaswamy, Vidavalur, Ramesh, Villafaina, Santos, Violante, Francesco S, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vollset, Stein Emil, Vos, Theo, Vosoughi, Kia, Vujcic, Isidora S, Wagner, Gregory R, Wagnew, Fasil Wagnew Shiferaw, Waheed, Yasir, Wang, Yanping, Wang, Yuan-Pang, Wassie, Molla Mesele, Weiderpass, Elisabete, Weintraub, Robert G, Weiss, Daniel J, Weiss, Jordan, Weldegebreal, Fitsum, Weldegwergs, Kidu Gidey, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A, Widecka, Justyna, Widecka, Katarzyna, Wijeratne, Tissa, Winkler, Andrea Sylvia, Wiysonge, Charles Shey, Wolfe, Charles D A, Wondemagegn, Sintayehu Ambachew, Wu, Shouling, Wyper, Grant M A, Xu, Gelin, Yadav, Rajaram, Yakob, Bereket, Yamada, Tomohide, Yan, Lijing L, Yano, Yuichiro, Yaseri, Mehdi, Yasin, Yasin Jemal, Ye, Pengpeng, Yearwood, Jamal A, Yentür, Gökalp Kadri, Yeshaneh, Alex, Yimer, Ebrahim M, Yip, Paul, Yisma, Engida, Yonemoto, Naohiro, Yoon, Seok-Jun, York, Hunter W, Yotebieng, Marcel, Younis, Mustafa Z, Yousefifard, Mahmoud, Yu, Chuanhua, Zachariah, Geevar, Zadnik, Vesna, Zafar, Shamsa, Zaidi, Zoubida, Zaman, Sojib Bin, Zamani, Mohammad, Zare, Zohreh, Zeeb, Hajo, Zeleke, Mulugeta Molla, Zenebe, Zerihun Menlkalew, Zerfu, Taddese Alemu, Zhang, Kai, Zhang, Xueying, Zhou, Maigeng, Zhu, Jun, Zodpey, Sanjay, Zucker, Inbar, Zuhlke, Liesl Joanna J, Lopez, Alan D, Gakidou, Emmanuela, and Murray, Christopher J L
- Subjects
1. No poverty ,10. No inequality ,3. Good health
46. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015
- Author
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Suleman, Atique, Euripide, Frinel, G, Arthur, Avokpaho, Ashish, Awasthi, Peter, Azzopardi, Umar, Bacha, Alaa, Badawi, Maria, C, Bahit, Kalpana, Balakrishnan, Amitava, Banerjee, Aleksandra, Barac, Suzanne, L, Barker-Collo, Till, Bärnighausen, Lars, Barregard, Lope, H, Barrero, Arindam, Basu, Sanjay, Basu, Yibeltal, Tebekaw, Bayou, Shahrzad, Bazargan-Hejazi, Justin, Beardsley, Neeraj, Bedi, Ettore, Beghi, Haileeyesus, Adamu, Belay, Brent, Bell, Michelle, L, Bell, Aminu, K, Bello, Derrick, A, Bennett, Isabela, M, Bensenor, Adugnaw, Berhane, Eduardo, Bernabé, Balem, Demtsu, Betsu, Addisu, Shunu, Beyene, Neeraj, Bhala, Ashish, Bhalla, Sibhatu, Biadgilign, Boris, Bikbov, Aref, A, Bin, Abdulhak, Brian, J, Biroscak, Stan, Biryukov, Espen, Bjertne, Jed, D, Blore, Christopher, D, Blosser, Megan, A, Bohensky, Rohan, Borschmann, Dipan, Bose, Rupert, R, A, Bourne, Michael, Brainin, Carol, E, G, Brayne, Alexandra, Brazinova, Nicholas, J, K, Breitborde, Hermann, Brenner, Jerry, D, Brewer, Alexandria, 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Avokpaho, Euripide Frinel G Arthur, Awasthi, Ashish, Azzopardi, Peter, Bacha, Umar, Badawi, Alaa, Bahit, Maria C, Balakrishnan, Kalpana, Banerjee, Amitava, Barac, Aleksandra, Barker-Collo, Suzanne L, Bärnighausen, Till, Barregard, Lar, Barrero, Lope H, Basu, Arindam, Basu, Sanjay, Bayou, Yibeltal Tebekaw, Bazargan-Hejazi, Shahrzad, Beardsley, Justin, Bedi, Neeraj, Beghi, Ettore, Belay, Haileeyesus Adamu, Bell, Brent, Bell, Michelle L, Bello, Aminu K, Bennett, Derrick A, Bensenor, Isabela M, Berhane, Adugnaw, Bernabé, Eduardo, Betsu, Balem Demtsu, Beyene, Addisu Shunu, Bhala, Neeraj, Bhalla, Ashish, Biadgilign, Sibhatu, Bikbov, Bori, Abdulhak, Aref A Bin, Biroscak, Brian J, Biryukov, Stan, Bjertness, Espen, Blore, Jed D, Blosser, Christopher D, Bohensky, Megan A, Borschmann, Rohan, Bose, Dipan, Bourne, Rupert R A, Brainin, Michael, Brayne, Carol E G, Brazinova, Alexandra, Breitborde, Nicholas J K, Brenner, Hermann, Brewer, Jerry D, Brown, Alexandria, Brown, Jonathan, Brugha, Traolach S, Buckle, Geoffrey Colin, Butt, Zahid A, Calabria, Bianca, Campos-Nonato, Ismael Ricardo, Campuzano, Julio Cesar, Carapetis, Jonathan R, Cárdenas, Rosario, Carpenter, David O, Carrero, Juan Jesu, Castañeda-Orjuela, Carlos A, Rivas, Jacqueline Castillo, Catalá-López, Ferrán, Cavalleri, Fiorella, Cercy, Kelly, Cerda, Jorge, Chen, Wanqing, Chew, Adrienne, Chiang, Peggy Pei-Chia, Chibalabala, Mirriam, Chibueze, Chioma Ezinne, Chimed-Ochir, Odgerel, Chisumpa, Vesper Hichilombwe, Choi, Jee-Young Jasmine, Chowdhury, Rajiv, Christensen, Hanne, Christopher, Devasahayam Jesuda, Ciobanu, Liliana G, Cohen, Aaron J, Colistro, Valentina, Colomar, Mercede, Colquhoun, Samantha M, Cooper, Cyru, Cooper, Leslie Trumbull, Cortinovis, Monica, Cowie, Benjamin C, Crump, John A, Damsere-Derry, Jame, Danawi, Hadi, Dandona, Rakhi, Daoud, Farah, Darby, Sarah C, Dargan, Paul I, das Neves, José, Davey, Gail, Davis, Adrian C, Davitoiu, Dragos V, de Castro, E Filipa, de Jager, Pieter, Leo, Diego De, Degenhardt, Louisa, Dellavalle, Robert P, Deribe, Kebede, Deribew, Amare, Dharmaratne, Samath D, Dhillon, Preet K, Diaz-Torné, Cesar, Ding, Eric L, dos Santos, Kadine Priscila Bender, Dossou, Edem, Driscoll, Tim R, Duan, Leilei, Dubey, Manisha, Duncan, Bruce Bartholow, Ellenbogen, Richard G, Ellingsen, Christian Lycke, Elyazar, Iqbal, Endries, Aman Yesuf, Ermakov, Sergey Petrovich, Eshrati, Babak, Esteghamati, Alireza, Estep, Kara, Faghmous, Imad D A, Fahimi, Saman, Faraon, Emerito Jose Aquino, Farid, Talha A, Farinha, Carla Sofia e Sa, Faro, André, Farvid, Maryam S, Farzadfar, Farshad, Feigin, Valery L, Fereshtehnejad, Seyed-Mohammad, Fernandes, Jefferson G, Fernandes, Joao C, Fischer, Florian, Fitchett, Joseph R A, Flaxman, Abraham, Foigt, Nataliya, Fowkes, F Gerry R, Franca, Elisabeth Barboza, Franklin, Richard C, Friedman, Joseph, Frostad, Joseph, Fürst, Thoma, Futran, Neal D, Gall, Seana L, Gambashidze, Ketevan, Gamkrelidze, Amiran, Ganguly, Parthasarathi, Gankpé, Fortuné Gbètoho, Gebre, Teshome, Gebrehiwot, Tsegaye Tsewelde, Gebremedhin, Amanuel Tesfay, Gebru, Alemseged Aregay, Geleijnse, Johanna M, Gessner, Bradford D, Ghoshal, Aloke Gopal, Gibney, Katherine B, Gillum, Richard F, Gilmour, Stuart, Giref, Ababi Zergaw, Giroud, Maurice, Gishu, Melkamu Dedefo, Giussani, Giorgia, Glaser, Elizabeth, Godwin, William W, Gomez-Dantes, Hector, Gona, Philimon, Goodridge, Amador, Gopalani, Sameer Vali, Gosselin, Richard A, Gotay, Carolyn C, Goto, Atsushi, Gouda, Hebe N, Greaves, Felix, Gugnani, Harish Chander, Gupta, Rahul, Gupta, Rajeev, Gupta, Vipin, Gutiérrez, Reyna A, Hafezi-Nejad, Nima, Haile, Demewoz, Hailu, Alemayehu Desalegne, Hailu, Gessessew Bugssa, Halasa, Yara A, Hamadeh, Randah Ribhi, Hamidi, Samer, Hancock, Jamie, Handal, Alexis J, Hankey, Graeme J, Hao, Yuantao, Harb, Hilda L, Harikrishnan, Sivadasanpillai, Haro, Josep Maria, Havmoeller, Rasmu, Heckbert, Susan R, Heredia-Pi, Ileana Beatriz, Heydarpour, Pouria, Hilderink, Henk B M, Hoek, Hans W, Hogg, Robert S, Horino, Masako, Horita, Nobuyuki, Hosgood, H Dean, Hotez, Peter J, Hoy, Damian G, Hsairi, Mohamed, Htet, Aung Soe, Htike, Maung Maung Than, Hu, Guoqing, Huang, Cheng, Huang, Hsiang, Huiart, Laetitia, Husseini, Abdullatif, Huybrechts, Inge, Huynh, Grace, Iburg, Kim Moesgaard, Innos, Kaire, Inoue, Manami, Iyer, Veena J, Jacobs, Troy A, Jacobsen, Kathryn H, Jahanmehr, Nader, Jakovljevic, Mihajlo B, James, Peter, Javanbakht, Mehdi, Jayaraman, Sudha P, Jayatilleke, Achala Upendra, Jeemon, Panniyammakal, Jensen, Paul N, Jha, Vivekanand, Jiang, Guohong, Jiang, Ying, Jibat, Tariku, Jimenez-Corona, Aida, Jonas, Jost B, Joshi, Tushar Kant, Kabir, Zubair, Kamal, Ritul, Kan, Haidong, Kant, Surya, Karch, André, Karema, Corine Kakizi, Karimkhani, Chante, Karletsos, Dimitri, Karthikeyan, Ganesan, Kasaeian, Amir, Katibeh, Marzieh, Kaul, Anil, Kawakami, Norito, Kayibanda, Jeanne Françoise, Keiyoro, Peter Njenga, Kemmer, Laura, Kemp, Andrew Haddon, Kengne, Andre Pascal, Keren, Andre, Kereselidze, Maia, Kesavachandran, Chandrasekharan Nair, Khader, Yousef Saleh, Khalil, Ibrahim A, Khan, Abdur Rahman, Khan, Ejaz Ahmad, Khang, Young-Ho, Khera, Sahil, Khoja, Tawfik Ahmed Muthafer, Kieling, Christian, Kim, Daniel, Kim, Yun Jin, Kissela, Brett M, Kissoon, Niranjan, Knibbs, Luke D, Knudsen, Ann Kristin, Kokubo, Yoshihiro, Kolte, Dhaval, Kopec, Jacek A, Kosen, Soewarta, Koul, Parvaiz A, Koyanagi, Ai, Krog, Norun Hjertager, Defo, Barthelemy Kuate, Bicer, Burcu Kucuk, Kudom, Andreas A, Kuipers, Ernst J, Kulkarni, Veena S, Kumar, G Anil, Kwan, Gene F, Lal, Aparna, Lal, Dharmesh Kumar, Lalloo, Ratilal, Lam, Hilton, Lam, Jennifer O, Langan, Sinead M, Lansingh, Van C, Larsson, Ander, Laryea, Dennis Odai, Latif, Asma Abdul, Lawrynowicz, Alicia Elena Beatriz, Leigh, Jame, Levi, Miriam, Li, Yongmei, Lindsay, M Patrice, Lipshultz, Steven E, Liu, Patrick Y, Liu, Shiwei, Liu, Yang, Lo, Loon-Tzian, Logroscino, Giancarlo, Lotufo, Paulo A, Lucas, Robyn M, Lunevicius, Raimunda, Lyons, Ronan A, Ma, Stefan, Machado, Vasco Manuel Pedro, Mackay, Mark T, Maclachlan, Jennifer H, Razek, Hassan Magdy Abd El, Magdy, Mohammed, Razek, Abd El, Majdan, Marek, Majeed, Azeem, Malekzadeh, Reza, Manamo, Wondimu Ayele Ayele, Mandisarisa, John, Mangalam, Srikanth, Mapoma, Chabila C, Marcenes, Wagner, Margolis, David Joel, Martin, Gerard Robert, Martinez-Raga, Jose, Marzan, Melvin Barriento, Masiye, Felix, Mason-Jones, Amanda J, Massano, João, Matzopoulos, Richard, Mayosi, Bongani M, Mcgarvey, Stephen Theodore, Mcgrath, John J, Mckee, Martin, Mcmahon, Brian J, Meaney, Peter A, Mehari, Alem, Mehndiratta, Man Mohan, Mejia-Rodriguez, Fabiola, Mekonnen, Alemayehu B, Melaku, Yohannes Adama, Memiah, Peter, Memish, Ziad A, Mendoza, Walter, Meretoja, Atte, Meretoja, Tuomo J, Mhimbira, Francis Apolinary, Micha, Renata, Miller, Ted R, Mirarefin, Mojde, Misganaw, Awoke, Mock, Charles N, Mohammad, Karzan Abdulmuhsin, Mohammadi, Alireza, Mohammed, Shafiu, Mohan, Viswanathan, Mola, Glen Liddell D, Monasta, Lorenzo, Hernandez, Julio Cesar Montañez, Montero, Pablo, Montico, Marcella, Montine, Thomas J, Moradi-Lakeh, Maziar, Morawska, Lidia, Morgan, Katherine, Mori, Rintaro, Mozaffarian, Dariush, Mueller, Ulrich O, Murthy, Gudlavalleti Venkata Satyanarayana, Murthy, Sriniva, Musa, Kamarul Imran, Nachega, Jean B, Nagel, Gabriele, Naidoo, Kovin S, Naik, Nitish, Naldi, Luigi, Nangia, Vinay, Nash, Deni, Nejjari, Chakib, Neupane, Suba, Newton, Charles R, Newton, John N, Ng, Marie, Ngalesoni, Frida Namnyak, de Dieu Ngirabega, Jean, Nguyen, Quyen Le, Nisar, Muhammad Imran, Pete, Patrick Martial Nkamedjie, Nomura, Marika, Norheim, Ole F, Norman, Paul E, Norrving, Bo, Nyakarahuka, Luke, Ogbo, Felix Akpojene, Ohkubo, Takayoshi, Ojelabi, Foluke Adetola, Olivares, Pedro R, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Opio, John Nelson, Oren, Eyal, Ortiz, Alberto, Osman, Majdi, Ota, Erika, Ozdemir, Raziye, Pa, Mahesh, Pandian, Jeyaraj D, Pant, Puspa Raj, Papachristou, Christina, Park, Eun-Kee, Park, Jae-Hyun, Parry, Charles D, Parsaeian, Mahboubeh, Caicedo, Angel J Paternina, Patten, Scott B, Patton, George C, Paul, Vinod K, Pearce, Neil, Pedro, João Mário, Stokic, Ljiljana Pejin, Pereira, David M, Perico, Norberto, Pesudovs, Konrad, Petzold, Max, Phillips, Michael Robert, Piel, Frédéric B, Pillay, Julian David, Plass, Dietrich, Platts-Mills, James A, Polinder, Suzanne, Pope, C Arden, Popova, Svetlana, Poulton, Richie G, Pourmalek, Farshad, Prabhakaran, Dorairaj, Qorbani, Mostafa, Quame-Amaglo, Justice, Quistberg, D Alex, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Vafa, Rahman, Mahfuzar, Rahman, Mohammad Hifz Ur, Rahman, Sajjad Ur, Rai, Rajesh Kumar, Rajavi, Zhale, Rajsic, Sasa, Raju, Murugesan, Rakovac, Ivo, Rana, Saleem M, Ranabhat, Chhabi L, Rangaswamy, Thara, Rao, Puja, Rao, Sowmya R, Refaat, Amany H, Rehm, Jürgen, Reitsma, Marissa B, Remuzzi, Giuseppe, Resnikoff, Serge, Ribeiro, Antonio L, Ricci, Stefano, Blancas, Maria Jesus Rio, Roberts, Bayard, Roca, Anna, Rojas-Rueda, David, Ronfani, Luca, Roshandel, Gholamreza, Rothenbacher, Dietrich, Roy, Ambuj, Roy, Nawal K, Ruhago, George Mugambage, Sagar, Rajesh, Saha, Sukanta, Sahathevan, Ramesh, Saleh, Muhammad Muhammad, Sanabria, Juan R, Sanchez-Niño, Maria Dolore, Sanchez-Riera, Lidia, Santos, Itamar S, Sarmiento-Suarez, Rodrigo, Sartorius, Benn, Satpathy, Maheswar, Savic, Miloje, Sawhney, Monika, Schaub, Michael P, Schmidt, Maria Inê, Schneider, Ione J C, Schöttker, Ben, Schutte, Aletta E, Schwebel, David C, Seedat, Soraya, Sepanlou, Sadaf G, Servan-Mori, Edson E, Shackelford, Katya A, Shaddick, Gavin, Shaheen, Amira, Shahraz, Saeid, Shaikh, Masood Ali, Shakh-Nazarova, Marina, Sharma, Rajesh, She, Jun, Sheikhbahaei, Sara, Shen, Jiabin, Shen, Ziyan, Shepard, Donald S, Sheth, Kevin N, Shetty, Balakrishna P, Shi, Peilin, Shibuya, Kenji, Shin, Min-Jeong, Shiri, Rahman, Shiue, Ivy, Shrime, Mark G, Sigfusdottir, Inga Dora, Silberberg, Donald H, Silva, Diego Augusto Santo, Silveira, Dayane Gabriele Alve, Silverberg, Jonathan I, Simard, Edgar P, Singh, Abhishek, Singh, Gitanjali M, Singh, Jasvinder A, Singh, Om Prakash, Singh, Prashant Kumar, Singh, Virendra, Soneji, Samir, Søreide, Kjetil, Soriano, Joan B, Sposato, Luciano A, Sreeramareddy, Chandrashekhar T, Stathopoulou, Vasiliki, Stein, Dan J, Stein, Murray B, Stranges, Saverio, Stroumpoulis, Konstantino, Sunguya, Bruno F, Sur, Patrick, Swaminathan, Soumya, Sykes, Bryan L, Szoeke, Cassandra E I, Tabarés-Seisdedos, Rafael, Tabb, Karen M, Takahashi, Ken, Takala, Jukka S, Talongwa, Roberto Tchio, Tandon, Nikhil, Tavakkoli, Mohammad, Taye, Bineyam, Taylor, Hugh R, Ao, Braden J Te, Tedla, Bemnet Amare, Tefera, Worku Mekonnen, Have, Margreet Ten, Terkawi, Abdullah Sulieman, Tesfay, Fisaha Haile, Tessema, Gizachew Assefa, Thomson, Alan J, Thorne-Lyman, Andrew L, Thrift, Amanda G, Thurston, George D, Tillmann, Taavi, Tirschwell, David L, Tonelli, Marcello, Topor-Madry, Roman, Topouzis, Foti, Towbin, Jeffrey Allen, Traebert, Jefferson, Tran, Bach Xuan, Truelsen, Thoma, Trujillo, Ulise, Tura, Abera Kenay, Tuzcu, Emin Murat, Uchendu, Uche S, Ukwaja, Kingsley N, Undurraga, Eduardo A, Uthman, Olalekan A, Dingenen, Rita Van, van Donkelaar, Aaron, Vasankari, Tommi, Vasconcelos, Ana Maria Nogale, Venketasubramanian, Narayanaswamy, Vidavalur, Ramesh, Vijayakumar, Lakshmi, Villalpando, Salvador, Violante, Francesco S, Vlassov, Vasiliy Victorovich, Wagner, Joseph A, Wagner, Gregory R, Wallin, Mitchell T, Wang, Linhong, Watkins, David A, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Werdecker, Andrea, Westerman, Ronny, White, Richard A, Wijeratne, Tissa, Wilkinson, James D, Williams, Hywel C, Wiysonge, Charles Shey, Woldeyohannes, Solomon Meseret, Wolfe, Charles D A, Won, Sungho, Wong, John Q, Woolf, Anthony D, Xavier, Deni, Xiao, Qingyang, Xu, Gelin, Yakob, Bereket, Yalew, Ayalnesh Zemene, Yan, Lijing L, Yano, Yuichiro, Yaseri, Mehdi, Ye, Pengpeng, Yebyo, Henock Gebremedhin, Yip, Paul, Yirsaw, Biruck Desalegn, Yonemoto, Naohiro, Yonga, Gerald, Younis, Mustafa Z, Yu, Shicheng, Zaidi, Zoubida, Zaki, Maysaa El Sayed, Zannad, Faiez, Zavala, Diego E, Zeeb, Hajo, Zeleke, Berihun M, Zhang, Hao, Zodpey, Sanjay, Zonies, David, Zuhlke, Liesl Joanna, Vos, Theo, Lopez, Alan D, and Murray, Christopher J L
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VITAL-STATISTICS ,INTEGRATED APPROACH ,ECONOMIC-DEVELOPMENT ,DEVELOPMENT ASSISTANCE ,UNITED-STATES ,Global Health ,Communicable Disease ,Communicable Diseases ,cause of death ,Medicine, General & Internal ,Life Expectancy ,General & Internal Medicine ,Humans ,Mortality ,Medicine(all) ,Science & Technology ,Mortality, Premature ,Medicine (all) ,EPIDEMIOLOGIC TRANSITION ,GBD 2015 Mortality and Causes of Death Collaborators ,CIVIL REGISTRATION ,Public Health, Global Health, Social Medicine and Epidemiology ,Articles ,11 Medical And Health Sciences ,ROAD TRAFFIC INJURIES ,ALZHEIMERS-DISEASE ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,VERBAL AUTOPSY ,Life Sciences & Biomedicine ,Human - Abstract
Background Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015. These results informed an in-depth investigation of observed and expected mortality patterns based on sociodemographic measures. Methods We estimated all-cause mortality by age, sex, geography, and year using an improved analytical approach originally developed for GBD 2013 and GBD 2010. Improvements included refinements to the estimation of child and adult mortality and corresponding uncertainty, parameter selection for under-5 mortality synthesis by spatiotemporal Gaussian process regression, and sibling history data processing. We also expanded the database of vital registration, survey, and census data to 14 294 geography-year datapoints. For GBD 2015, eight causes, including Ebola virus disease, were added to the previous GBD cause list for mortality. We used six modelling approaches to assess cause-specific mortality, with the Cause of Death Ensemble Model (CODEm) generating estimates for most causes. We used a series of novel analyses to systematically quantify the drivers of trends in mortality across geographies. First, we assessed observed and expected levels and trends of cause-specific mortality as they relate to the Socio-demographic Index (SDI), a summary indicator derived from measures of income per capita, educational attainment, and fertility. Second, we examined factors affecting total mortality patterns through a series of counterfactual scenarios, testing the magnitude by which population growth, population age structures, and epidemiological changes contributed to shifts in mortality. Finally, we attributed changes in life expectancy to changes in cause of death. We documented each step of the GBD 2015 estimation processes, as well as data sources, in accordance with Guidelines for Accurate and Transparent Health Estimates Reporting (GATHER). Findings Globally, life expectancy from birth increased from 61.7 years (95% uncertainty interval 61.4-61.9) in 1980 to 71.8 years (71.5-72.2) in 2015. Several countries in sub-Saharan Africa had very large gains in life expectancy from 2005 to 2015, rebounding from an era of exceedingly high loss of life due to HIV/AIDS. At the same time, many geographies saw life expectancy stagnate or decline, particularly for men and in countries with rising mortality from war or interpersonal violence. From 2005 to 2015, male life expectancy in Syria dropped by 11.3 years (3.7-17.4), to 62.6 years (56.5-70.2). Total deaths increased by 4.1% (2.6-5.6) from 2005 to 2015, rising to 55.8 million (54.9 million to 56.6 million) in 2015, but age-standardised death rates fell by 17.0% (15.8-18.1) during this time, underscoring changes in population growth and shifts in global age structures. The result was similar for non-communicable diseases (NCDs), with total deaths from these causes increasing by 14.1% (12.6-16.0) to 39.8 million (39.2 million to 40.5 million) in 2015, whereas age-standardised rates decreased by 13.1% (11.9-14.3). Globally, this mortality pattern emerged for several NCDs, including several types of cancer, ischaemic heart disease, cirrhosis, and Alzheimer's disease and other dementias. By contrast, both total deaths and age-standardised death rates due to communicable, maternal, neonatal, and nutritional conditions significantly declined from 2005 to 2015, gains largely attributable to decreases in mortality rates due to HIV/AIDS (42.1%, 39.1-44.6), malaria (43.1%, 34.7-51.8), neonatal preterm birth complications (29.8%, 24.8-34.9), and maternal disorders (29.1%, 19.3-37.1). Progress was slower for several causes, such as lower respiratory infections and nutritional deficiencies, whereas deaths increased for others, including dengue and drug use disorders. Age-standardised death rates due to injuries significantly declined from 2005 to 2015, yet interpersonal violence and war claimed increasingly more lives in some regions, particularly in the Middle East. In 2015, rotaviral enteritis (rotavirus) was the leading cause of under-5 deaths due to diarrhoea (146 000 deaths, 118 000-183 000) and pneumococcal pneumonia was the leading cause of under-5 deaths due to lower respiratory infections (393 000 deaths, 228 000-532 000), although pathogen-specific mortality varied by region. Globally, the effects of population growth, ageing, and changes in age-standardised death rates substantially differed by cause. Our analyses on the expected associations between cause-specific mortality and SDI show the regular shifts in cause of death composition and population age structure with rising SDI. Country patterns of premature mortality (measured as years of life lost [YLLs]) and how they differ from the level expected on the basis of SDI alone revealed distinct but highly heterogeneous patterns by region and country or territory. Ischaemic heart disease, stroke, and diabetes were among the leading causes of YLLs in most regions, but in many cases, intraregional results sharply diverged for ratios of observed and expected YLLs based on SDI. Communicable, maternal, neonatal, and nutritional diseases caused the most YLLs throughout sub-Saharan Africa, with observed YLLs far exceeding expected YLLs for countries in which malaria or HIV/AIDS remained the leading causes of early death. Interpretation At the global scale, age-specific mortality has steadily improved over the past 35 years; this pattern of general progress continued in the past decade. Progress has been faster in most countries than expected on the basis of development measured by the SDI. Against this background of progress, some countries have seen falls in life expectancy, and age-standardised death rates for some causes are increasing. Despite progress in reducing age-standardised death rates, population growth and ageing mean that the number of deaths from most non-communicable causes are increasing in most countries, putting increased demands on health systems. Copyright (C) The Author(s). Published by Elsevier Ltd.
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- 2016
47. Georacial Epidemiological Estimates of Glucose-6-Phosphate Dehydrogenase Deficiency among Newborns in the United States.
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Vidavalur R and Bhutani VK
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- Humans, Infant, Newborn, United States epidemiology, Female, Prevalence, Male, Gene Frequency, Genotype, Glucosephosphate Dehydrogenase Deficiency epidemiology, Glucosephosphate Dehydrogenase Deficiency genetics
- Abstract
Objective: Glucose-6-phosphate dehydrogenase deficiency (G6PDd) is the most common inherited enzyme deficiency disorder worldwide and a major risk factor for the development of severe hyperbilirubinemia. Racial diversity of phenotypes and genotypes in affected individuals is likely to exist in the United States because of changing population demographics. The aim of the present study was to predict an empirical estimate of annual prevalence of G6PDd in newborns adjusted for geography (state of birth), maternal racial identity, and sex of the infant., Study Design: Birth statistics (2019) from National Center for Vital Statistics and CDC-WONDER data and race-specific prevalence of G6PDd in the United States were evaluated from published sources. We developed Simpson's diversity index (DI) for each State and correlated these to rates of G6PDd in neonates. Descriptive statistics including modeled prevalence and its association with DI were assessed using the Spearman's rho correlation test. We modeled state-specific prevalence for six states (California, Washington DC, Illinois, Massachusetts, New York, and Pennsylvania) using population-level allele frequencies and race, based on Hardy-Weinberg equilibrium., Results: We estimated 78,010 (95% confidence interval: 76,768-79,252) newborns had G6PDd at birth in 2019 with cumulative median prevalence of 17.3 (interquartile range: 12.4-23.2) per 1,000 live births for United States. A strong association was noted for DI and prevalence of G6PDd ( p < 0.0005). Five states (Washington DC, Mississippi, Louisiana, Georgia, and Maryland) have the highest projected G6PDd prevalence, with a range of 35 to 48 per 1,000 live births. The probability of G6PDd for female heterozygotes, based on male prevalence, ranged from 1.1 to 7.5% for each cohort in the select six states., Conclusion: States with diverse populations are likely to have higher rates of G6PDd. These prevalence estimates exceeded by several-fold when compared with disorders screened by existing state mandated newborn screening panels. These discrepancies are further confounded by known risk of severe neonatal hyperbilirubinemia that results with G6PDd and the life-long risk of hemolysis. Combined universal newborn predischarge screening for G6PDd and bilirubin could alert and guide a clinician's practices for parental education and closer medical surveillance during the vulnerable neonatal time period., Key Points: · G6PDd is a common X-linked disorder that can present with varied phenotypes among newborns.. · Prevalence of G6PDd and genotype distribution varies with sex, race, and ethnicity.. · We present regional race- and sex-based estimates of G6PDd in the United States.., Competing Interests: None declared., (Thieme. All rights reserved.)
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- 2024
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48. Interstate Practice Variation and Factors Associated with Antibiotic Use for Suspected Neonatal Sepsis in the United States.
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Vidavalur R and Hussain N
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- Humans, Infant, Newborn, United States epidemiology, Female, Cross-Sectional Studies, Retrospective Studies, Male, Gestational Age, Pregnancy, Neonatal Sepsis drug therapy, Neonatal Sepsis epidemiology, Anti-Bacterial Agents therapeutic use, Practice Patterns, Physicians' statistics & numerical data, Chorioamnionitis epidemiology, Chorioamnionitis drug therapy
- Abstract
Objective: This study aimed to estimate national time trends of overall and statewise antibiotic utilization (AU) rates for suspected neonatal sepsis (SNS) in the United States., Study Design: In this cross-sectional study, we used retrospective linked birth cohort and vital records data from the Centers for Disease Control and Prevention Wide-ranging ONline Data for Epidemiologic Research database for the years 2016 to 2020 and analyzed data containing antibiotic use for SNS. The primary outcome was proportional national and state-specific AU rates per 1,000 live births during the birth hospitalization. Secondary outcomes included overall trends and association between maternal education, race, sex, chorioamnionitis, mode of delivery, gestational age at birth, Apgar's scores, and insurance status with antibiotics exposure for SNS among newborns. Contingency tables, two-tailed t -test, and chi-square for independence tests were performed with statistical significance set at p < 0.05., Results: For a birth cohort of >18 million, 2.2% of infants received antibiotics during birth hospitalization nationwide. There were wide variations in AU among U.S. states and territories, whereas overall treatment rates decreased by 16.1% (95% confidence interval [CI]: 15.2-17.0; p < 0.001). Compared with White newborns, Black newborns had higher AU rates (odds ratio [OR]: 1.33; 95% CI: 1.32-1.34), and Asians had the lowest rates (OR: 0.96; 95% CI: 0.95-0.97). There was a significant difference in mean AU rates by race ( p < 0.001). Chorioamnionitis at birth significantly increased the odds for AU (OR: 14.5 ;95% CI: 14.4-14.6), although AU rates for chorioamnionitis showed a significant downward trend (OR: 0.52; 95% CI: 0.50-0.53) during the study period., Conclusion: Our findings suggest that there has been a gradual decline in AU for SNS in more than a third of states in last 5 years. While risk-based management approaches achieve widespread implementation, state- and nationwide quality improvement collaborates might have contributed to the relative decline in antibiotic use in newborns. Further studies are warranted to understand factors related to practice variation in the management of SNS in the United States KEY POINTS: · Early and prolonged use of antibiotics can lead to altered gut microbiome and adverse long-term neonatal outcomes.. · There is considerable clinical practice variation in antibiotic-prescribing practices for suspected neonatal sepsis.. · This cross-sectional study reports the differences in neonatal antibiotic usage patterns by region and maternal factors.. · Antibiotic use should be limited to newborns at high risk of infection and proven sepsis.. · Judicious use of antibiotics can be promoted by following evidence-based approaches to sepsis risk assessment.., Competing Interests: None declared., (Thieme. All rights reserved.)
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- 2024
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49. Infantile hemangiomas and retinopathy of prematurity: possible association.
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Praveen V, Vidavalur R, Rosenkrantz TS, and Hussain N
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- Adrenal Cortex Hormones administration & dosage, Adrenal Cortex Hormones adverse effects, Cohort Studies, Comorbidity, Female, Gestational Age, Hemangioma blood, Hemangioma diagnosis, Humans, Infant, Extremely Low Birth Weight, Infant, Newborn, Infant, Very Low Birth Weight, Insulin-Like Growth Factor I metabolism, Male, Retinopathy of Prematurity blood, Retinopathy of Prematurity diagnosis, Retrospective Studies, Risk Factors, Skin Neoplasms blood, Skin Neoplasms diagnosis, Statistics as Topic, Vascular Endothelial Growth Factor A blood, Hemangioma epidemiology, Retinopathy of Prematurity epidemiology, Skin Neoplasms epidemiology
- Abstract
Objective: The goal was to study the clinical association between infantile hemangiomas and retinopathy of prematurity in preterm infants., Methods: A retrospective study of preterm neonates weighing =1250 g at birth who were born during a 5-year period (November 1, 2000, to October 31, 2005) at John Dempsey Hospital was performed by using a prospectively collected, neonatal database. Data were collected on demographic features (gestational age, birth weight, and gender) and prenatal/postnatal steroid use. In the physical examination at discharge, all infants were checked for infantile hemangiomas, and the size and number of lesions were noted. The highest stage of retinopathy of prematurity diagnosed at any time before discharge also was noted. Analyses were performed to identify associated risk factors., Results: Of 406 neonates admitted with birth weights of =1250 g, 351 (86.4%) survived. Of the survivors, 49 (13.9%) had infantile hemangiomas at discharge. Infantile hemangiomas were present for 16.8% of neonates with retinopathy of prematurity, compared with 6.7% of those without retinopathy of prematurity. Multiple infantile hemangiomas were present in 14 (28.5%) of 49 neonates, whereas 18 (42.8%) of 42 neonates had infantile hemangiomas that were >/=1 cm in size. Univariate analyses showed lower gestational age, lower birth weight, and postnatal steroid use to be predictors of retinopathy of prematurity, whereas prenatal steroid use, race, and gender were not significantly related. In multivariate logistic regression analyses controlling for gestational age and postnatal steroid use, infantile hemangiomas were found to be independently associated with any stage of retinopathy of prematurity. Neither the number nor the size of infantile hemangiomas showed any association with the severity of retinopathy of prematurity., Conclusions: Infantile hemangiomas are associated with the development of retinopathy of prematurity in infants weighing =1250 g. The biological significance of this association may yield clues to the management of retinopathy of prematurity.
- Published
- 2009
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50. Significance of wine and resveratrol in cardiovascular disease: French paradox revisited.
- Author
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Vidavalur R, Otani H, Singal PK, and Maulik N
- Abstract
Many recent studies have reported promising health benefits from red wine consumption. The present article reviews some of the key studies, and the known mechanisms for these beneficial effects. Evidence from different experimental studies, including from the authors' laboratories, have suggested that these beneficial effects are due to polyphenols found in red wine, especially resveratrol in grape skins. These benefits include a reduction in cardiovascular morbidity and mortality, lung cancer and prostate cancer by approximately 30% to 50%, 57% and 50%, respectively. Polyphenols possess antioxidant, superoxide-scavenging, ischemic-preconditioning and angiogenic properties. Some of these properties of polyphenols may explain their protective effects on the cardiovascular system, as well as other body organs. In fact, results from several epidemiological, case-control and prospective studies have prompted the United States Department of Health and Human Services to recommend moderate alcohol consumption in its national health promotion and disease prevention initiative, Healthy People 2010. Further studies are warranted to describe the precise molecular mechanisms for these potential beneficial effects of red wine on the general health of the population, particularly on cardiovascular morbidity and mortality.
- Published
- 2006
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