Role of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency and Altered Redox Status in Racial Disparities of Neonatal Outcomes: An Innocent Bystander or Unaccused Accomplice?

The article focuses on the prevalence and implications of Glucose-6-phosphate dehydrogenase (G6PD) deficiency, the most common inherited enzymopathy worldwide, emphasizing its connection to prematurity and racial disparities in perinatal outcomes, particularly in African American infants, citing potential risks of hyperbilirubinemia, neurotoxicity, and various morbidities associated with G6PD deficiency in preterm infants.