1. Protein losing gastroenteropathy due to Helicobacter pylori infection without giant rugal folds, erosion or polyposis.
- Author
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Yoshioka K, Kishibuchi M, and Takada K
- Subjects
- Aged, 80 and over, Anti-Bacterial Agents administration & dosage, Anti-Bacterial Agents therapeutic use, Diagnosis, Differential, Drug Therapy, Combination, Edema diagnosis, Edema etiology, Endoscopy methods, Female, Gastric Mucosa diagnostic imaging, Gastric Mucosa microbiology, Gastric Mucosa pathology, Gastrointestinal Diseases diagnostic imaging, Gastrointestinal Diseases physiopathology, Helicobacter Infections diagnosis, Helicobacter Infections drug therapy, Helicobacter Infections pathology, Helicobacter pylori drug effects, Humans, Hypoproteinemia etiology, Protein-Losing Enteropathies drug therapy, Protein-Losing Enteropathies pathology, Pyrroles administration & dosage, Pyrroles therapeutic use, Radionuclide Imaging methods, Sulfonamides administration & dosage, Sulfonamides therapeutic use, Technetium Tc 99m Aggregated Albumin metabolism, Treatment Outcome, Helicobacter Infections complications, Hypoproteinemia diagnosis, Protein-Losing Enteropathies diagnostic imaging, Protein-Losing Enteropathies etiology
- Abstract
An 85-year-old woman was admitted to our hospital because of progressive hypoproteinemia and generalised oedema. Technetium-99m human albumin scintigraphy revealed protein leakage in the gastrointestinal tract. Upper gastrointestinal endoscopy revealed small whitish nodules from the gastric body up to the duodenal bulb. The urease test for Helicobacter pylori infection was positive. We diagnosed her as having protein-losing gastroenteropathy (PLGE) caused by H. pylori infection. The patient's hypoproteinemia and clinical symptoms promptly resolved after H. pylori eradication. Our results suggest that a trial of H. pylori eradication is warranted in patients with PLGE, even if endoscopy reveals neither giant rugal folds, erosion of the mucosa, nor polyposis, which are previously reported characteristic endoscopic findings of PLGE., Competing Interests: Competing interests: None declared., (© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2019
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