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78 results on '"Struan F. A. Grant"'

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1. A framework for conducting GWAS using repeated measures data with an application to childhood BMI

2. Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism

3. Translation of genome-wide association study: from genomic signals to biological insights

4. Author Correction: Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes

5. Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes

6. Projecting genetic associations through gene expression patterns highlights disease etiology and drug mechanisms

7. Genome-wide association studies and fine-mapping identify genomic loci for n-3 and n-6 polyunsaturated fatty acids in Hispanic American and African American cohorts

8. Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis

9. Human height: a model common complex trait

10. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

11. Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes

12. Implicating effector genes at COVID-19 GWAS loci using promoter-focused Capture-C in disease-relevant immune cell types

13. Using linear and natural cubic splines, SITAR, and latent trajectory models to characterise nonlinear longitudinal growth trajectories in cohort studies

14. CYP11B1 variants influence skeletal maturation via alternative splicing

15. Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits

16. Identification of 22 susceptibility loci associated with testicular germ cell tumors

17. Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual

18. Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells

19. Rare copy number variants in over 100,000 European ancestry subjects reveal multiple disease associations

20. Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

21. Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density

22. Relevance of polymorphisms in MC4R and BDNF in short normal stature

23. Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes

24. Genetic Susceptibility to Type 2 Diabetes and Obesity: Follow-Up of Findings from Genome-Wide Association Studies

25. Genetics of Obesity and Type 2 Diabetes in African Americans

27. Genetics of Childhood Obesity

29. Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function

30. New insights into the genetic etiology of Alzheimer's disease and related dementias

33. Strategies to identify causal common genetic variants and corresponding effector genes for paediatric obesity

34. Variant-to-gene-mapping analyses reveal a role for pancreatic islet cells in conferring genetic susceptibility to sleep-related traits

36. Leveraging genetic discoveries for sleep to determine causal relationships with common complex traits

37. CRISPR‐Cas9–Mediated Genome Editing Confirms EPDR1 as an Effector Gene at the BMD GWAS‐Implicated ‘STARD3NL’ Locus

38. A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

39. Leveraging putative enhancer-promoter interactions to investigate two-way epistasis in Type 2 Diabetes GWAS

40. Prevalence of diabetes in Australia: insights from the Fremantle Diabetes Study Phase II

41. PARP-1 Inhibition Rescues Short Lifespan in Hyperglycemic

44. Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study

45. Developmental origins of genotype-phenotype correlations in chronic diseases of old age

46. Obesity-susceptibility loci and the tails of the pediatric BMI distribution

47. The missense variation landscape of FTO, MC4R, and TMEM18 in obese children of African Ancestry

48. Genome-wide association studies (GWAS): impact on elucidating the aetiology of diabetes

49. Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT)

50. Association between a high-risk autism locus on 5p14 and social communication spectrum phenotypes in the general population

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