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New insights into the genetic etiology of Alzheimer's disease and related dementias
- Authors :
- Bellenguez, C.
Küçükali, F.
Jansen, I. E.
Kleineidam, L.
Moreno-Grau, S.
Amin, N.
Naj, A. C.
Campos-Martin, R.
Grenier-Boley, B.
Andrade, V.
Holmans, P. A.
Boland, A.
Damotte, V.
van der Lee, S. J.
Costa, M. R.
Kuulasmaa, T.
Yang, Q.
de Rojas, I.
Bis, J. C.
Yaqub, A.
Prokic, I.
Chapuis, J.
Ahmad, S.
Giedraitis, V.
Aarsland, D.
Garcia-Gonzalez, P.
Abdelnour, C.
Alarcón-Martín, E.
Alcolea, D.
Alegret, M.
Alvarez, I.
Álvarez, V.
Armstrong, N. J.
Tsolaki, A.
Antúnez, C.
Appollonio, I.
Arcaro, M.
Archetti, S.
Pastor, A. A.
Arosio, B.
Athanasiu, L.
Bailly, H.
Banaj, N.
Baquero, M.
Barral, S.
Beiser, A.
Pastor, A. B.
Below, J. E.
Benchek, P.
Benussi, L.
Berr, C.
Besse, C.
Bessi, V.
Binetti, G.
Bizarro, A.
Blesa, R.
Boada, M.
Boerwinkle, E.
Borroni, B.
Boschi, S.
Bossù, P.
Bråthen, G.
Bressler, J.
Bresner, C.
Brodaty, H.
Brookes, K. J.
Brusco, L. I.
Buiza-Rueda, D.
Bûrger, K.
Burholt, V.
Bush, W. S.
Calero, M.
Cantwell, L. B.
Chene, G.
Chung, J.
Cuccaro, M. L.
Carracedo, Á.
Cecchetti, R.
Cervera-Carles, L.
Charbonnier, C.
Chen, H. -H.
Chillotti, C.
Ciccone, S.
Claassen, J. A. H. R.
Clark, C.
Conti, E.
Corma-Gómez, A.
Costantini, E.
Custodero, C.
Daian, D.
Dalmasso, M. C.
Daniele, A.
Dardiotis, E.
Dartigues, J. -F.
de Deyn, P. P.
de Paiva Lopes, K.
de Witte, L. D.
Debette, S.
Deckert, J.
del Ser, T.
Denning, N.
Destefano, A.
Dichgans, M.
Diehl-Schmid, J.
Diez-Fairen, M.
Rossi, P. D.
Djurovic, S.
Duron, E.
Düzel, E.
Dufouil, C.
Eiriksdottir, G.
Engelborghs, S.
Escott-Price, V.
Espinosa, A.
Ewers, M.
Faber, K. M.
Fabrizio, T.
Nielsen, S. F.
Fardo, D. W.
Farotti, L.
Fenoglio, C.
Fernández-Fuertes, M.
Ferrari, R.
Ferreira, C. B.
Ferri, E.
Fin, B.
Fischer, P.
Fladby, T.
Fließbach, K.
Fongang, B.
Fornage, M.
Fortea, J.
Foroud, T. M.
Fostinelli, S.
Fox, N. C.
Franco-Macías, E.
Bullido, M. J.
Frank-García, A.
Froelich, L.
Fulton-Howard, B.
Galimberti, D.
García-Alberca, J. M.
García-González, P.
Garcia-Madrona, S.
Garcia-Ribas, G.
Ghidoni, R.
Giegling, I.
Giorgio, G.
Goate, A. M.
Goldhardt, O.
Gomez-Fonseca, D.
González-Pérez, A.
Graff, C.
Grande, G.
Green, E.
Grimmer, T.
Grünblatt, E.
Grunin, M.
Gudnason, V.
Guetta-Baranes, T.
Haapasalo, A.
Hadjigeorgiou, G.
Haines, J. L.
Hamilton-Nelson, K. L.
Hampel, H.
Hanon, O.
Hardy, J.
Hartmann, A. M.
Hausner, L.
Harwood, J.
Heilmann-Heimbach, S.
Helisalmi, S.
Heneka, M. T.
Hernández, I.
Herrmann, M. J.
Hoffmann, P.
Holmes, C.
Holstege, H.
Vilas, R. H.
Hulsman, M.
Humphrey, J.
Biessels, G. J.
Jian, X.
Johansson, C.
Jun, G. R.
Kastumata, Y.
Kauwe, J.
Kehoe, P. G.
Kilander, L.
Ståhlbom, A. K.
Kivipelto, M.
Koivisto, A.
Kornhuber, J.
Kosmidis, M. H.
Kukull, W. A.
Kuksa, P. P.
Kunkle, B. W.
Kuzma, A. B.
Lage, C.
Laukka, E. J.
Launer, L.
Lauria, A.
Lee, C. -Y.
Lehtisalo, J.
Lerch, O.
Lleó, A.
Longstreth, W.
Lopez, O.
de Munain, A. L.
Love, S.
Löwemark, M.
Luckcuck, L.
Lunetta, K. L.
Ma, Y.
Macías, J.
Macleod, C. A.
Maier, W.
Mangialasche, F.
Spallazzi, M.
Marquié, M.
Marshall, R.
Martin, E. R.
Montes, A. M.
Rodríguez, C. M.
Masullo, C.
Mayeux, R.
Mead, S.
Mecocci, P.
Medina, M.
Meggy, A.
Mehrabian, S.
Mendoza, S.
Menéndez-González, M.
Mir, P.
Moebus, S.
Mol, M.
Molina-Porcel, L.
Montrreal, L.
Morelli, L.
Moreno, F.
Morgan, K.
Mosley, T.
Nöthen, M. M.
Muchnik, C.
Mukherjee, S.
Nacmias, B.
Ngandu, T.
Nicolas, G.
Nordestgaard, B. G.
Olaso, R.
Orellana, A.
Orsini, M.
Ortega, G.
Padovani, A.
Paolo, C.
Papenberg, G.
Parnetti, L.
Pasquier, F.
Pastor, P.
Peloso, G.
Pérez-Cordón, A.
Pérez-Tur, J.
Pericard, P.
Peters, O.
Pijnenburg, Y. A. L.
Pineda, J. A.
Piñol-Ripoll, G.
Pisanu, C.
Polak, T.
Popp, J.
Posthuma, D.
Priller, J.
Puerta, R.
Quenez, O.
Quintela, I.
Thomassen, J. Q.
Rábano, A.
Rainero, I.
Rajabli, F.
Ramakers, I.
Real, L. M.
Reinders, M. J. T.
Reitz, C.
Reyes-Dumeyer, D.
Ridge, P.
Riedel-Heller, S.
Riederer, P.
Roberto, N.
Rodriguez-Rodriguez, E.
Rongve, A.
Allende, I. R.
Rosende-Roca, M.
Royo, J. L.
Rubino, E.
Rujescu, D.
Sáez, M. E.
Sakka, P.
Saltvedt, I.
Sanabria, Á.
Sánchez-Arjona, M. B.
Sanchez-Garcia, F.
Juan, P. S.
Sánchez-Valle, R.
Sando, S. B.
Sarnowski, C.
Satizabal, C. L.
Scamosci, M.
Scarmeas, N.
Scarpini, E.
Scheltens, P.
Scherbaum, N.
Scherer, M.
Schmid, M.
Schneider, A.
Schott, J. M.
Selbæk, G.
Seripa, D.
Serrano, M.
Sha, J.
Shadrin, A. A.
Skrobot, O.
Slifer, S.
Snijders, G. J. L.
Soininen, H.
Solfrizzi, V.
Solomon, A.
Song, Y. E.
Sorbi, S.
Sotolongo-Grau, O.
Spalletta, G.
Spottke, A.
Squassina, A.
Stordal, E.
Tartan, J. P.
Tárraga, L.
Tesí, N.
Thalamuthu, A.
Thomas, T.
Tosto, G.
Traykov, L.
Tremolizzo, L.
Tybjærg-Hansen, A.
Uitterlinden, A.
Ullgren, A.
Ulstein, I.
Valero, S.
Valladares, O.
Broeckhoven, C. V.
Vance, J.
Vardarajan, B. N.
van der Lugt, A.
Dongen, J. V.
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van Swieten, J.
Vandenberghe, R.
Verhey, F.
Vidal, J. -S.
Vogelgsang, J.
Vyhnalek, M.
Wagner, M.
Wallon, D.
Wang, L. -S.
Wang, R.
Weinhold, L.
Wiltfang, J.
Windle, G.
Woods, B.
Yannakoulia, M.
Zare, H.
Zhao, Y.
Zhang, X.
Zhu, C.
Zulaica, M.
Laczo, J.
Matoska, V.
Serpente, M.
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Ciullo, V.
Shofany, J.
Ferrarese, C.
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Sala, G.
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Benussi, A.
Bastiani, P.
Takalo, M.
Natunen, T.
Laatikainen, T.
Tuomilehto, J.
Antikainen, R.
Strandberg, T.
Lindström, J.
Peltonen, M.
Abraham, R.
Al-Chalabi, A.
Bass, N. J.
Brayne, C.
Brown, K. S.
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Craig, D.
Deloukas, P.
Fox, N.
Gerrish, A.
Gill, M.
Gwilliam, R.
Harold, D.
Hollingworth, P.
Johnston, J. A.
Jones, L.
Lawlor, B.
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Heap, G.
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Lu, T.
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Miller, M.
Mccarthy, L.
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Kaipiainen-Seppänen, O.
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della Briotta Parola, P.
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Lähteenmäki, S.
Männikkö, L.
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Hiekkalinna, T.
Paajanen, T.
Pärn, K.
Gracia-Tabuenca, J.
Abner, E.
Adams, P. M.
Aguirre, A.
Albert, M. S.
Albin, R. L.
Allen, M.
Alvarez, L.
Apostolova, L. G.
Arnold, S. E.
Asthana, S.
Atwood, C. S.
Ayres, G.
Baldwin, C. T.
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Barnes, L. L.
Beach, T. G.
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Beecham, G. W.
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Chesselet, M. -F.
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Crocco, E. A.
Cruchaga, C.
Cullum, M.
Darby, E.
Davis, B.
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Decarli, C.
Detoledo, J.
Dick, M.
Dickson, D. W.
Dombroski, B. A.
Doody, R. S.
Duara, R.
Ertekin-Taner, N.
Evans, D. A.
Fairchild, T. J.
Fallon, K. B.
Farlow, M. R.
Farrell, J. J.
Fernandez-Hernandez, V.
Ferris, S.
Frosch, M. P.
Galasko, D. R.
Gamboa, A.
Gearing, M.
Geschwind, D. H.
Ghetti, B.
Gilbert, J. R.
Grabowski, T. J.
Graff-Radford, N. R.
Grant, S. F. A.
Green, R. C.
Growdon, J. H.
Hakonarson, H.
Hall, J.
Hamilton, R. L.
Harari, O.
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Reisberg, B.
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Roberson, E. D.
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Royall, D. R.
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Sano, M.
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Vaclav, Matoska
Maria, Serpente
Francesca, Assogna
Fabrizio, Piras
Federica, Piras
Valentina, Ciullo
Jacob, Shofany
Carlo, Ferrarese
Simona, Andreoni
Gessica, Sala
Chiara Paola Zoia
Maria Del Zompo
Benussi, Alberto
Patrizia, Bastiani
Mari, Takalo
Teemu, Natunen
Tiina, Laatikainen
Jaakko, Tuomilehto
Riitta, Antikainen
Timo, Strandberg
Jaana, Lindström
Markku, Peltonen
Richard, Abraham
Ammar, Al-Chalabi
Nicholas, J Bass
Carol, Brayne
Kristelle, S Brown
John, Collinge
David, Craig
Pangiotis, Deloukas
Nick, Fox
Amy, Gerrish
Michael, Gill
Rhian, Gwilliam
Denise, Harold
Paul, Hollingworth
Jarret, A Johnston
Lesley, Jones
Brian, Lawlor
Gill, Livingston
Simon, Lovestone
Michelle, Lupton
Aoibhinn, Lynch
David, Mann
Bernadette, Mcguinness
Andrew, Mcquillin
Michael, C O'Donovan
Michael, J Owen
Peter, Passmore
John, F Powell
Petra, Proitsi
Martin, Rossor
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A David Smith
Hugh, Gurling
Stephen, Todd
Catherine, Mummery
Nathalie, Ryan
Giordano, Lacidogna
Adarmes-Gómez, Ad
Ana, Mauleón
Ana, Pancho
Anna, Gailhajenet
Asunción, Lafuente
Macias-García, D
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Garrote-Espina, L
Liliana, Vargas
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Labrador, Ma
Mar, Buendia
María Dolores Alonso
Marina, Guitart
Mariona, Moreno
Marta, Ibarria
Periñán, Mt
Nuria, Aguilera
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Pilar, Cañabate
Escuela, R
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Silvia, Preckler
Silvia, Rodrigo-Herrero
Susana, Diego
Alessandro, Vacca
Fausto, Roveta
Nicola, Salvadori
Elena, Chipi
Henning, Boecker
Christoph, Laske
Robert, Perneczky
Costas, Anastasiou
Daniel, Janowitz
Rainer, Malik
Anna, Anastasiou
Kayenat, Parveen
Carmen, Lage
Sara, López-García
Anna, Antonell
Kalina Yonkova Mihova
Diyana, Belezhanska
Heike, Weber
Silvia, Kochen
Patricia, Solis
Nancy, Medel
Julieta, Lisso
Zulma, Sevillano
Daniel, G Politis
Valeria, Cores
Carolina, Cuesta
Cecilia, Ortiz
Juan Ignacio Bacha
Mario, Rios
Aldo, Saenz
Mariana Sanchez Abalos
Eduardo, Kohler
Dana Lis Palacio
Ignacio, Etchepareborda
Matias, Kohler
Gisela, Novack
Federico Ariel Prestia
Pablo, Galeano
Eduardo, M Castaño
Sandra, Germani
Carlos Reyes Toso
Matias, Rojo
Carlos, Ingino
Carlos, Mangone
David, C Rubinsztein
Stefan, Teipel
Nathalie, Fievet
Vincent, Deramerourt
Charlotte, Forsell
Håkan, Thonberg
Maria, Bjerke
Ellen De Roeck
María Teresa Martínez-Larrad
Natividad, Olivar
Amanda, Cano
Juan, Macias
Olalla, Maroñas
Raúl, Nuñez-Llaves
Clàudia, Olivé
Ester, Pelejá
Astrid, D Adarmes-Gómez
Guillermo, Amer-Ferrer
Martirio, Antequera
Juan Andrés Burguera
Fátima, Carrillo
Mario, Carrión-Claro
María José Casajeros
Marian Martinez de Pancorbo
Rocío, Escuela
Lorena, Garrote-Espina
Pilar, Gómez-Garre
Saray, Hevilla
Silvia, Jesús
Miguel Angel Labrador Espinosa
Agustina, Legaz
Daniel, Macias-García
Salvadora, Manzanares
Marta, Marín
Juan, Marín-Muñoz
Tamara, Marín
Begoña, Martínez
Victoriana, Martínez
Pablo Martínez-Lage Álvarez
Maite Mendioroz Iriarte
María Teresa Periñán-Tocino
Rocío, Pineda-Sánchez
Diego Real de Asúa
Silvia, Rodrigo
Isabel, Sastre
Maria Pilar Vicente
Rosario, Vigo-Ortega
Liliana, Vivancos
Jacques, Epelbaum
Didier, Hannequin
Dominique, Campion
Vincent, Deramecourt
Christophe, Tzourio
Alexis, Brice
Bruno, Dubois
Amy, Williams
Charlene, Thomas
Chloe, Davies
William, Nash
Kimberley, Dowzell
Atahualpa Castillo Morales
Mateus, Bernardo-Harrington
James, Turton
Jenny, Lord
Kristelle, Brown
Emma, Vardy
Elizabeth, Fisher
Jason, D Warren
Natalie, S Ryan
Rita, Guerreiro
James, Uphill
Nick, Bass
Reinhard, Heun
Heike, Kölsch
Britta, Schürmann
André, Lacour
Christine, Herold
Janet, A Johnston
John, Powell
Yogen, Patel
Angela, Hodges
Tim, Becker
Donald, Warden
Gordon, Wilcock
Robert, Clarke
Panagiotis, Deloukas
Yoav, Ben-Shlomo
Nigel, M Hooper
Stuart, Pickering-Brown
Rebecca, Sussams
Nick, Warner
Anthony, Bayer
Isabella, Heuser
Dmitriy, Drichel
Norman, Klopp
Manuel, Mayhaus
Matthias, Riemenschneider
Sabrina, Pinchler
Thomas, Feulner
Wei, Gu
Hendrik van den Bussche
Michael, Hüll
Lutz, Frölich
H-Erich, Wichmann
Karl-Heinz, Jöckel
Michael, O'Donovan
Michael, Owen
Shahram, Bahrami
Ingunn, Bosnes
Per, Selnes
Sverre, Bergh
Aarno, Palotie
Mark, Daly
Howard, Jacob
Athena, Matakidou
Heiko, Runz
Sally, John
Robert, Plenge
Mark, Mccarthy
Julie, Hunkapiller
Meg, Ehm
Dawn, Waterworth
Caroline, Fox
Anders, Malarstig
Kathy, Klinger
Kathy, Call
Tim, Behrens
Patrick, Loerch
Tomi, Mäkelä
Jaakko, Kaprio
Petri, Virolainen
Kari, Pulkki
Terhi, Kilpi
Markus, Perola
Jukka, Partanen
Anne, Pitkäranta
Riitta, Kaarteenaho
Seppo, Vainio
Miia, Turpeinen
Raisa, Serpi
Tarja, Laitinen
Johanna, Mäkelä
Veli-Matti, Kosma
Urho, Kujala
Outi, Tuovila
Minna, Hendolin
Raimo, Pakkanen
Jeff, Waring
Bridget, Riley-Gillis
Jimmy, Liu
Shameek, Biswas
Dorothee, Diogo
Catherine, Marshall
Xinli, Hu
Matthias, Gossel
Robert, Graham
Beryl, Cummings
Samuli, Ripatti
Johanna, Schleutker
Mikko, Arvas
Olli, Carpén
Reetta, Hinttala
Johannes, Kettunen
Arto, Mannermaa
Jari, Laukkanen
Valtteri, Julkunen
Anne, Remes
Reetta, Kälviäinen
Jukka, Peltola
Pentti, Tienari
Juha, Rinne
Adam, Ziemann
Jeffrey, Waring
Sahar, Esmaeeli
Nizar, Smaoui
Anne, Lehtonen
Susan, Eaton
Sanni, Lahdenperä
Janet van Adelsberg
John, Michon
Geoff, Kerchner
Natalie, Bowers
Edmond, Teng
John, Eicher
Vinay, Mehta
Padhraig, Gormley
Kari, Linden
Christopher, Whelan
Fanli, Xu
David, Pulford
Martti, Färkkilä
Sampsa, Pikkarainen
Airi, Jussila
Timo, Blomster
Mikko, Kiviniemi
Markku, Voutilainen
Bob, Georgantas
Graham, Heap
Fedik, Rahimov
Keith, Usiskin
Tim, Lu
Danny, Oh
Kirsi, Kalpala
Melissa, Miller
Linda, Mccarthy
Kari, Eklund
Antti, Palomäki
Pia, Isomäki
Laura, Pirilä
Oili, Kaipiainen-Seppänen
Johanna, Huhtakangas
Apinya, Lertratanakul
Marla, Hochfeld
Nan, Bing
Jorge Esparza Gordillo
Nina, Mars
Margit, Pelkonen
Paula, Kauppi
Hannu, Kankaanranta
Terttu, Harju
David, Close
Steven, Greenberg
Hubert, Chen
Betts, Jo
Soumitra, Ghosh
Veikko, Salomaa
Teemu, Niiranen
Markus, Juonala
Kaj, Metsärinne
Mika, Kähönen
Juhani, Junttila
Markku, Laakso
Jussi, Pihlajamäki
Juha, Sinisalo
Marja-Riitta, Taskinen
Tiinamaija, Tuomi
Ben, Challis
Andrew, Peterson
Audrey, Chu
Jaakko, Parkkinen
Anthony, Muslin
Heikki, Joensuu
Tuomo, Meretoja
Lauri, Aaltonen
Johanna, Mattson
Annika, Auranen
Peeter, Karihtala
Saila, Kauppila
Päivi, Auvinen
Klaus, Elenius
Relja, Popovic
Jennifer, Schutzman
Andrey, Loboda
Aparna, Chhibber
Heli, Lehtonen
Stefan, Mcdonough
Marika, Crohns
Diptee, Kulkarni
Kai, Kaarniranta
Joni, A Turunen
Terhi, Ollila
Sanna, Seitsonen
Hannu, Uusitalo
Vesa, Aaltonen
Hannele, Uusitalo-Järvinen
Marja, Luodonpää
Nina, Hautala
Stephanie, Loomis
Erich, Strauss
Hao, Chen
Anna, Podgornaia
Joshua, Hoffman
Kaisa, Tasanen
Laura, Huilaja
Katariina, Hannula-Jouppi
Teea, Salmi
Sirkku, Peltonen
Leena, Koulu
Ilkka, Harvima
Ying, Wu
David, Choy
Pirkko, Pussinen
Aino, Salminen
Tuula, Salo
David, Rice
Pekka, Nieminen
Ulla, Palotie
Maria, Siponen
Liisa, Suominen
Päivi, Mäntylä
Ulvi, Gursoy
Vuokko, Anttonen
Kirsi, Sipilä
Justin Wade Davis
Danjuma, Quarless
Slavé, Petrovski
Eleonor, Wigmore
Chia-Yen, Chen
Paola, Bronson
Ellen, Tsai
Yunfeng, Huang
Joseph, Maranville
Elmutaz, Shaikho
Elhaj, Mohammed
Samir, Wadhawan
Erika, Kvikstad
Minal, Caliskan
Diana, Chang
Tushar, Bhangale
Sarah, Pendergrass
Emily, Holzinger
Xing, Chen
Åsa, Hedman
Karen, S King
Clarence, Wang
Ethan, Xu
Franck, Auge
Clement, Chatelain
Deepak, Rajpal
Dongyu, Liu
Katherine, Call
Tai-He, Xia
Matt, Brauer
Mitja, Kurki
Juha, Karjalainen
Aki, Havulinna
Anu, Jalanko
Priit, Palta
Pietro Della Briotta Parolo
Wei, Zhou
Susanna, Lemmelä
Manuel, Rivas
Jarmo, Harju
Arto, Lehisto
Andrea, Ganna
Vincent, Llorens
Hannele, Laivuori
Sina, Rüeger
Mari, E Niemi
Taru, Tukiainen
Mary Pat Reeve
Henrike, Heyne
Kimmo, Palin
Javier, Garcia-Tabuenca
Harri, Siirtola
Tuomo, Kiiskinen
Jiwoo, Lee
Kristin, Tsuo
Amanda, Elliott
Kati, Kristiansson
Kati, Hyvärinen
Jarmo, Ritari
Miika, Koskinen
Katri, Pylkäs
Marita, Kalaoja
Minna, Karjalainen
Tuomo, Mantere
Eeva, Kangasniemi
Sami, Heikkinen
Eija, Laakkonen
Csilla, Sipeky
Samuel, Heron
Antti, Karlsson
Dhanaprakash, Jambulingam
Venkat Subramaniam Rathinakannan
Risto, Kajanne
Mervi, Aavikko
Manuel González Jiménez
Pietro Della Briotta Parola
Arto, Lehistö
Masahiro, Kanai
Mari, Kaunisto
Elina, Kilpeläinen
Timo, P Sipilä
Georg, Brein
Ghazal, Awaisa
Anastasia, Shcherban
Kati, Donner
Anu, Loukola
Päivi, Laiho
Tuuli, Sistonen
Essi, Kaiharju
Markku, Laukkanen
Elina, Järvensivu
Sini, Lähteenmäki
Lotta, Männikkö
Regis, Wong
Hannele, Mattsson
Tero, Hiekkalinna
Teemu, Paajanen
Kalle, Pärn
Javier, Gracia-Tabuenca
Erin, Abner
Perrie, M Adams
Alyssa, Aguirre
Marilyn, S Albert
Roger, L Albin
Mariet, Allen
Lisa, Alvarez
Liana, G Apostolova
Steven, E Arnold
Sanjay, Asthana
Craig, S Atwood
Gayle, Ayres
Clinton, T Baldwin
Robert, C Barber
Lisa, L Barnes
Sandra, Barral
Thomas, G Beach
James, T Becker
Gary, W Beecham
Duane, Beekly
Jennifer, E Below
Penelope, Benchek
Bruno, A Benitez
David, Bennett
John, Bertelson
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Thomas, D Bird
Deborah, Blacker
Bradley, F Boeve
James, D Bowen
Adam, Boxer
James, Brewer
James, R Burke
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Chuanhai, Cao
Christopher, S Carlson
Cynthia, M Carlsson
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Scott, Chasse
Marie-Francoise, Chesselet
Alessandra, Chesi
Nathaniel, A Chin
Helena, C Chui
Jaeyoon, Chung
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Paul, K Crane
David, H Cribbs
Elizabeth, A Crocco
Carlos, Cruchaga
Michael, L Cuccaro
Munro, Cullum
Eveleen, Darby
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Philip, L De Jager
Charles, Decarli
John, Detoledo
Malcolm, Dick
Dennis, W Dickson
Beth, A Dombroski
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Ranjan, Duara
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Denis, A Evans
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Victoria, Fernandez-Hernandez
Steven, Ferris
Matthew, P Frosch
Brian, Fulton-Howard
Douglas, R Galasko
Adriana, Gamboa
Marla, Gearing
Daniel, H Geschwind
Bernardino, Ghetti
John, R Gilbert
Thomas, J Grabowski
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Struan F, A Grant
Robert, C Green
John, H Growdon
Jonathan, L Haines
Hakon, Hakonarson
James, Hall
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Oscar, Harari
Lindy, E Harrell
Jacob, Haut
Elizabeth, Head
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Michelle, Hernandez
Timothy, Hohman
Lawrence, S Honig
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Matthew, J Huentelman
Christine, M Hulette
Bradley, T Hyman
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Laura, Ibanez
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Lee-Way, Jin
Kim, Johnson
Leigh, Johnson
M Ilyas Kamboh
Anna, M Karydas
Mindy, J Katz
Jeffrey, A Kaye
C Dirk Keene
Aisha, Khaleeq
Ronald, Kim
Janice, Knebl
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Joel, H Kramer
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James, J Lah
Eric, B Larson
Chien-Yueh, Lee
Edward, B Lee
Alan, Lerner
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James, B Leverenz
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Andrew, P Lieberman
Richard, B Lipton
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Sid, O'Bryant
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Raymond, Palmer
Joseph, E Parisi
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David, Paydarfar
Victoria, Perez
Elaine, Peskind
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Jennifer, E Phillips-Cremins
Aimee, Pierce
Marsha, Polk
Wayne, W Poon
Huntington, Potter
Liming, Qu
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Joseph, F Quinn
Ashok, Raj
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Eric, M Reiman
Barry, Reisberg
Joan, S Reisch
John, M Ringman
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Monica, Rodriguear
Ekaterina, Rogaeva
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Donald, R Royall
Mark, A Sager
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Andrew, J Saykin
Julie, A Schneider
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William, W Seeley
Susan, H Slifer
Scott, Small
Amanda, G Smith
Janet, P Smith
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Joshua, A Sonnen
Salvatore, Spina
Peter St George-Hyslop
Robert, A Stern
Alan, B Stevens
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David, Sultzer
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John, Q Trojanowski
Juan, C Troncoso
Debby, W Tsuang
Otto, Valladares
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Robert, Vassar
Harry, V Vinters
Jean-Paul, Vonsattel
Sandra, Weintraub
Kathleen, A Welsh-Bohmer
Patrice, L Whitehead
Ellen, M Wijsman
Kirk, C Wilhelmsen
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Jennifer, Williamson
Henrik, Wilms
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Martin, Woon
Clinton, B Wright
Chuang-Kuo, Wu
Steven, G Younkin
Chang-En, Yu
Lei, Yu
Yuanchao, Zhang
Zhao, Yi
Xiongwei, Zhu
Hieab, Adams
Rufus, O Akinyemi
Muhammad, Ali
Nicola, Armstrong
Hugo, J Aparicio
Maryam, Bahadori
Monique, Breteler
Daniel, Chasman
Ganesh, Chauhan
Hata, Comic
Simon, Cox
Adrienne, L Cupples
Gail, Davies
Charles, S DeCarli
Marie-Gabrielle, Duperron
Josée, Dupuis
Tavia, Evans
Frank, Fan
Annette, Fitzpatrick
Alison, E Fohner
Mary, Ganguli
Mirjam, Geerlings
Stephen, J Glatt
Hector, M Gonzalez
Monica, Goss
Hans, Grabe
Mohamad, Habes
Susan, R Heckbert
Edith, Hofer
Elliot, Hong
Timothy, Hughes
Tiffany, F Kautz
Maria, Knol
William, Kremen
Paul, Lacaze
Jari, Lahti
Quentin Le Grand
Elizabeth, Litkowski
Shuo, Li
Dan, Liu
Xuan, Liu
Marisa, Loitfelder
Alisa, Manning
Pauline, Maillard
Riccardo, Marioni
Bernard, Mazoyer
Debora Melo van Lent
Hao, Mei
Aniket, Mishra
Paul, Nyquist
Jeffrey, O'Connell
Yash, Patel
Tomas, Paus
Zdenka, Pausova
Katri, Raikkonen-Talvitie
Moeen, Riaz
Stephen, Rich
Jerome, Rotter
Jose, Romero
Gena, Roshchupkin
Yasaman, Saba
Murali, Sargurupremraj
Helena, Schmidt
Reinhold, Schmidt
Joshua, M Shulman
Jennifer, Smith
Hema, Sekhar
Reddy, Rajula
Jean, Shin
Jeannette, Simino
Eeva, Sliz
Alexander, Teumer
Alvin, Thomas
Adrienne, Tin
Elliot, Tucker-Drob
Dina, Vojinovic
Yanbing, Wang
Galit, Weinstein
Dylan, Williams
Katharina, Wittfeld
Lisa, Yanek
Yunju, Yang
Bellenguez, C
Küçükali, F
Jansen, I
Kleineidam, L
Moreno-Grau, S
Amin, N
Naj, A
Campos-Martin, R
Grenier-Boley, B
Andrade, V
Holmans, P
Boland, A
Damotte, V
van der Lee, S
Costa, M
Kuulasmaa, T
Yang, Q
de Rojas, I
Bis, J
Yaqub, A
Prokic, I
Chapuis, J
Ahmad, S
Giedraitis, V
Aarsland, D
Garcia-Gonzalez, P
Abdelnour, C
Alarcón-Martín, E
Alcolea, D
Alegret, M
Alvarez, I
Álvarez, V
Armstrong, N
Tsolaki, A
Antúnez, C
Appollonio, I
Arcaro, M
Archetti, S
Pastor, A
Arosio, B
Athanasiu, L
Bailly, H
Banaj, N
Baquero, M
Barral, S
Beiser, A
Below, J
Benchek, P
Benussi, L
Berr, C
Besse, C
Bessi, V
Binetti, G
Bizarro, A
Blesa, R
Boada, M
Boerwinkle, E
Borroni, B
Boschi, S
Bossù, P
Bråthen, G
Bressler, J
Bresner, C
Brodaty, H
Brookes, K
Brusco, L
Buiza-Rueda, D
Bûrger, K
Burholt, V
Bush, W
Calero, M
Cantwell, L
Chene, G
Chung, J
Cuccaro, M
Carracedo, Á
Cecchetti, R
Cervera-Carles, L
Charbonnier, C
Chen, H
Chillotti, C
Ciccone, S
Claassen, J
Clark, C
Conti, E
Corma-Gómez, A
Costantini, E
Custodero, C
Daian, D
Dalmasso, M
Daniele, A
Dardiotis, E
Dartigues, J
de Deyn, P
de Paiva Lopes, K
de Witte, L
Debette, S
Deckert, J
Del Ser, T
Denning, N
Destefano, A
Dichgans, M
Diehl-Schmid, J
Diez-Fairen, M
Rossi, P
Djurovic, S
Duron, E
Düzel, E
Dufouil, C
Eiriksdottir, G
Engelborghs, S
Escott-Price, V
Espinosa, A
Ewers, M
Faber, K
Fabrizio, T
Nielsen, S
Fardo, D
Farotti, L
Fenoglio, C
Fernández-Fuertes, M
Ferrari, R
Ferreira, C
Ferri, E
Fin, B
Fischer, P
Fladby, T
Fließbach, K
Fongang, B
Fornage, M
Fortea, J
Foroud, T
Fostinelli, S
Fox, N
Franco-Macías, E
Bullido, M
Frank-García, A
Froelich, L
Fulton-Howard, B
Galimberti, D
García-Alberca, J
García-González, P
Garcia-Madrona, S
Garcia-Ribas, G
Ghidoni, R
Giegling, I
Giorgio, G
Goate, A
Goldhardt, O
Gomez-Fonseca, D
González-Pérez, A
Graff, C
Grande, G
Green, E
Grimmer, T
Grünblatt, E
Grunin, M
Gudnason, V
Guetta-Baranes, T
Haapasalo, A
Hadjigeorgiou, G
Haines, J
Hamilton-Nelson, K
Hampel, H
Hanon, O
Hardy, J
Hartmann, A
Hausner, L
Harwood, J
Heilmann-Heimbach, S
Helisalmi, S
Heneka, M
Hernández, I
Herrmann, M
Hoffmann, P
Holmes, C
Holstege, H
Vilas, R
Hulsman, M
Humphrey, J
Biessels, G
Jian, X
Johansson, C
Jun, G
Kastumata, Y
Kauwe, J
Kehoe, P
Kilander, L
Ståhlbom, A
Kivipelto, M
Koivisto, A
Kornhuber, J
Kosmidis, M
Kukull, W
Kuksa, P
Kunkle, B
Kuzma, A
Lage, C
Laukka, E
Launer, L
Lauria, A
Lee, C
Lehtisalo, J
Lerch, O
Lleó, A
Longstreth, W
Lopez, O
de Munain, A
Love, S
Löwemark, M
Luckcuck, L
Lunetta, K
Ma, Y
Macías, J
Macleod, C
Maier, W
Mangialasche, F
Spallazzi, M
Marquié, M
Marshall, R
Martin, E
Montes, A
Rodríguez, C
Masullo, C
Mayeux, R
Mead, S
Mecocci, P
Medina, M
Meggy, A
Mehrabian, S
Mendoza, S
Menéndez-González, M
Mir, P
Moebus, S
Mol, M
Molina-Porcel, L
Montrreal, L
Morelli, L
Moreno, F
Morgan, K
Mosley, T
Nöthen, M
Muchnik, C
Mukherjee, S
Nacmias, B
Ngandu, T
Nicolas, G
Nordestgaard, B
Olaso, R
Orellana, A
Orsini, M
Ortega, G
Padovani, A
Paolo, C
Papenberg, G
Parnetti, L
Pasquier, F
Pastor, P
Peloso, G
Pérez-Cordón, A
Pérez-Tur, J
Pericard, P
Peters, O
Pijnenburg, Y
Pineda, J
Piñol-Ripoll, G
Pisanu, C
Polak, T
Popp, J
Posthuma, D
Priller, J
Puerta, R
Quenez, O
Quintela, I
Thomassen, J
Rábano, A
Rainero, I
Rajabli, F
Ramakers, I
Real, L
Reinders, M
Reitz, C
Reyes-Dumeyer, D
Ridge, P
Riedel-Heller, S
Riederer, P
Roberto, N
Rodriguez-Rodriguez, E
Rongve, A
Allende, I
Rosende-Roca, M
Royo, J
Rubino, E
Rujescu, D
Sáez, M
Sakka, P
Saltvedt, I
Sanabria, Á
Sánchez-Arjona, M
Sanchez-Garcia, F
Juan, P
Sánchez-Valle, R
Sando, S
Sarnowski, C
Satizabal, C
Scamosci, M
Scarmeas, N
Scarpini, E
Scheltens, P
Scherbaum, N
Scherer, M
Schmid, M
Schneider, A
Schott, J
Selbæk, G
Seripa, D
Serrano, M
Sha, J
Shadrin, A
Skrobot, O
Slifer, S
Snijders, G
Soininen, H
Solfrizzi, V
Solomon, A
Song, Y
Sorbi, S
Sotolongo-Grau, O
Spalletta, G
Spottke, A
Squassina, A
Stordal, E
Tartan, J
Tárraga, L
Tesí, N
Thalamuthu, A
Thomas, T
Tosto, G
Traykov, L
Tremolizzo, L
Tybjærg-Hansen, A
Uitterlinden, A
Ullgren, A
Ulstein, I
Valero, S
Valladares, O
Broeckhoven, C
Vance, J
Vardarajan, B
van der Lugt, A
Dongen, J
van Rooij, J
van Swieten, J
Vandenberghe, R
Verhey, F
Vidal, J
Vogelgsang, J
Vyhnalek, M
Wagner, M
Wallon, D
Wang, L
Wang, R
Weinhold, L
Wiltfang, J
Windle, G
Woods, B
Yannakoulia, M
Zare, H
Zhao, Y
Zhang, X
Zhu, C
Zulaica, M
Andreoni, S
Ferrarese, C
Sala, G
Zoia, C
Farrer, L
Psaty, B
Ghanbari, M
Raj, T
Sachdev, P
Mather, K
Jessen, F
Ikram, M
de Mendonça, A
Hort, J
Tsolaki, M
Pericak-Vance, M
Amouyel, P
Williams, J
Frikke-Schmidt, R
Clarimon, J
Deleuze, J
Rossi, G
Seshadri, S
Andreassen, O
Ingelsson, M
Hiltunen, M
Sleegers, K
Schellenberg, G
van Duijn, C
Sims, R
van der Flier, W
Ruiz, A
Ramirez, A
Lambert, J
VU University medical center
Amsterdam Neuroscience - Neurodegeneration
Neurology
Human genetics
Amsterdam Neuroscience - Complex Trait Genetics
Amsterdam Neuroscience - Compulsivity, Impulsivity & Attention
APH - Personalized Medicine
APH - Methodology
Bellenguez, Céline [0000-0002-1240-7874]
Küçükali, Fahri [0000-0002-3835-9639]
Amin, Najaf [0000-0002-8944-1771]
Holmans, Peter A [0000-0003-0870-9412]
van der Lee, Sven J [0000-0003-1606-8643]
Costa, Marcos R [0000-0002-4928-2163]
Kuulasmaa, Teemu [0000-0002-1795-7314]
Yang, Qiong [0000-0002-3658-1375]
de Rojas, Itziar [0000-0002-2148-381X]
Bis, Joshua C [0000-0002-3409-1110]
Yaqub, Amber [0000-0002-3579-8054]
Prokic, Ivana [0000-0002-0370-1473]
Chapuis, Julien [0000-0002-5802-2857]
Ahmad, Shahzad [0000-0002-8658-3790]
Giedraitis, Vilmantas [0000-0003-3423-2021]
Garcia-Gonzalez, Pablo [0000-0003-0125-5403]
Alcolea, Daniel [0000-0002-3819-3245]
Alvarez, Ignacio [0000-0002-8537-3935]
Tsolaki, Anthoula [0000-0002-5563-7776]
Baquero, Miquel [0000-0002-6861-1831]
Pastor, Ana Belén [0000-0001-9637-4688]
Berr, Claudine [0000-0001-5254-7655]
Bessi, Valentina [0000-0002-6176-3584]
Boada, Mercè [0000-0003-2617-3009]
Bossù, Paola [0000-0002-1432-0078]
Bråthen, Geir [0000-0003-3224-7983]
Bressler, Jan [0000-0001-6578-4772]
Bresner, Catherine [0000-0003-2673-9762]
Brodaty, Henry [0000-0001-9487-6617]
Brookes, Keeley J [0000-0003-2427-2513]
Burholt, Vanessa [0000-0002-6789-127X]
Bush, William S [0000-0002-9729-6519]
Calero, Miguel [0000-0001-5366-3324]
Chung, Jaeyoon [0000-0002-6431-9454]
Cervera-Carles, Laura [0000-0003-2286-200X]
Costantini, Emanuele [0000-0002-1096-8221]
Dalmasso, Maria Carolina [0000-0002-4901-9955]
de Paiva Lopes, Katia [0000-0002-0240-0126]
de Witte, Lot D [0000-0002-7235-9958]
Debette, Stéphanie [0000-0001-8675-7968]
Del Ser, Teodoro [0000-0001-9806-7083]
Dichgans, Martin [0000-0002-0654-387X]
Diehl-Schmid, Janine [0000-0002-7745-1382]
Diez-Fairen, Mónica [0000-0003-1882-0309]
Djurovic, Srdjan [0000-0002-8140-8061]
Dufouil, Carole [0000-0003-2442-4476]
Escott-Price, Valentina [0000-0003-1784-5483]
Ewers, Michael [0000-0001-5231-1714]
Fabrizio, Tagliavini [0000-0003-1039-7315]
Fladby, Tormod [0000-0002-9984-9797]
Fornage, Myriam [0000-0003-0677-8158]
Fox, Nick C [0000-0002-6660-657X]
Bullido, María J [0000-0002-6477-1117]
Froelich, Lutz [0000-0003-1494-0813]
Galimberti, Daniela [0000-0002-9284-5953]
García-Alberca, Jose Maria [0000-0003-2951-6644]
Goate, Alison M [0000-0002-0576-2472]
González-Pérez, Antonio [0000-0001-9771-5982]
Green, Emma [0000-0002-8687-5590]
Grünblatt, Edna [0000-0001-8505-7265]
Gudnason, Vilmundur [0000-0001-5696-0084]
Haapasalo, Annakaisa [0000-0003-0959-2957]
Harwood, Janet [0000-0002-3225-0069]
Heilmann-Heimbach, Stefanie [0000-0003-1057-465X]
Herrmann, Martin J [0000-0001-9970-2122]
Holstege, Henne [0000-0002-7688-3087]
Biessels, Geert Jan [0000-0001-6862-2496]
Jian, Xueqiu [0000-0002-0313-6494]
Johansson, Charlotte [0000-0002-5351-1950]
Jun, Gyungah R [0000-0002-3230-8697]
Kastumata, Yuriko [0000-0002-0188-8094]
Kehoe, Patrick G [0000-0002-7542-1139]
Kornhuber, Johannes [0000-0002-8096-3987]
Kosmidis, Mary H [0000-0001-8790-1220]
Lage, Carmen [0000-0003-1703-121X]
Launer, Lenore [0000-0002-3238-7612]
Lee, Chien-Yueh [0000-0002-4304-974X]
Lleó, Alberto [0000-0002-2568-5478]
Lopez, Oscar [0000-0002-8546-8256]
de Munain, Adolfo Lopez [0000-0002-9509-4032]
Lunetta, Kathryn L [0000-0002-9268-810X]
Ma, Yiyi [0000-0002-3609-8877]
MacLeod, Catherine A [0000-0002-9314-7380]
Marquié, Marta [0000-0002-0660-0950]
Montes, Angel Martín [0000-0002-1694-786X]
Mead, Simon [0000-0002-4326-1468]
Medina, Miguel [0000-0002-7016-5340]
Menéndez-González, Manuel [0000-0002-5218-0774]
Mol, Merel [0000-0003-2533-2530]
Morgan, Kevin [0000-0002-8217-2396]
Nöthen, Markus M [0000-0002-8770-2464]
Muchnik, Carolina [0000-0002-1542-3706]
Nacmias, Benedetta [0000-0001-9338-9040]
Nicolas, Gael [0000-0001-9391-7800]
Nordestgaard, Børge G [0000-0002-1954-7220]
Pasquier, Florence [0000-0001-9880-9788]
Pastor, Pau [0000-0002-7493-8777]
Peloso, Gina [0000-0002-5355-8636]
Pérez-Cordón, Alba [0000-0002-6028-0791]
Pérez-Tur, Jordi [0000-0002-9111-1712]
Pericard, Pierre [0000-0001-8167-6448]
Pineda, Juan A [0000-0002-3751-0296]
Pisanu, Claudia [0000-0002-9151-4319]
Posthuma, Danielle [0000-0001-7582-2365]
Puerta, Raquel [0000-0002-1191-5893]
Quenez, Olivier [0000-0002-8273-8505]
Thomassen, Jesper Qvist [0000-0003-3484-9531]
Real, Luis M [0000-0003-4932-7429]
Reinders, Marcel JT [0000-0002-1148-1562]
Reitz, Christiane [0000-0001-8757-7889]
Riedel-Heller, Steffi [0000-0003-4321-6090]
Rodriguez-Rodriguez, Eloy [0000-0001-7742-677X]
Rongve, Arvid [0000-0002-0476-4134]
Sáez, María Eugenia [0000-0001-9299-2534]
Saltvedt, Ingvild [0000-0002-7897-9808]
Juan, Pascual Sánchez [0000-0002-6081-8037]
Sarnowski, Chloé [0000-0002-6090-7099]
Satizabal, Claudia L [0000-0002-1115-4430]
Schott, Jonathan M [0000-0003-2059-024X]
Selbæk, Geir [0000-0001-6511-8219]
Shadrin, Alexey A [0000-0002-7467-250X]
Soininen, Hilkka [0000-0002-2785-9937]
Solfrizzi, Vincenzo [0000-0002-8524-0315]
Song, Yeunjoo [0000-0002-7452-3731]
Sotolongo-Grau, Oscar [0000-0002-9679-0670]
Spalletta, Gianfranco [0000-0002-7432-4249]
Squassina, Alessio [0000-0001-7415-7607]
Stordal, Eystein [0000-0002-2443-7923]
Tosto, Giuseppe [0000-0001-7075-8245]
Uitterlinden, Andre [0000-0002-7276-3387]
Valladares, Otto [0000-0001-8055-2187]
Broeckhoven, Christine Van [0000-0003-0183-7665]
Vidal, Jean-Sébastien [0000-0001-6770-0720]
Vogelgsang, Jonathan [0000-0001-9326-8193]
Wagner, Michael [0000-0003-2589-6440]
Wallon, David [0000-0002-2634-7198]
Wiltfang, Jens [0000-0003-1492-5330]
Woods, Bob [0000-0002-6781-651X]
Yannakoulia, Mary [0000-0003-2171-7337]
Zare, Habil [0000-0001-5902-6238]
Zhang, Xiaoling [0000-0001-8237-1857]
Farrer, Lindsay A [0000-0001-5533-4225]
Psaty, Bruce M [0000-0002-7278-2190]
Ghanbari, Mohsen [0000-0002-9476-7143]
Raj, Towfique [0000-0002-9355-5704]
Sachdev, Perminder [0000-0002-9595-3220]
Mather, Karen [0000-0003-4143-8941]
Ikram, M Arfan [0000-0003-0372-8585]
Tsolaki, Magda [0000-0002-2072-8010]
Pericak-Vance, Margaret A [0000-0001-7283-8804]
Amouyel, Philippe [0000-0001-9088-234X]
Williams, Julie [0000-0002-4069-0259]
Frikke-Schmidt, Ruth [0000-0003-4084-5027]
Seshadri, Sudha [0000-0001-6135-2622]
Andreassen, Ole A [0000-0002-4461-3568]
Sleegers, Kristel [0000-0002-0283-2332]
van Duijn, Cornelia M [0000-0002-2374-9204]
Sims, Rebecca [0000-0002-3885-1199]
van der Flier, Wiesje M [0000-0001-8766-6224]
Ramirez, Alfredo [0000-0003-4991-763X]
Lambert, Jean-Charles [0000-0003-0829-7817]
Apollo - University of Cambridge Repository
Complex Trait Genetics
Clinical sciences
Neuroprotection & Neuromodulation
Pathologic Biochemistry and Physiology
Clinical Biology
Epidemiology
Internal Medicine
Psychiatrie & Neuropsychologie
RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience
MUMC+: MA Med Staf Spec Psychiatrie (9)
UAM. Departamento de Biología Molecular
University of Helsinki
Department of Neurosciences
HUS Internal Medicine and Rehabilitation
Timo Strandberg / Principal Investigator
Department of Medicine
Clinicum
HUS Neurocenter
Neurologian yksikkö
Centre of Excellence in Complex Disease Genetics
HUS Abdominal Center
Institut Pasteur
Institut National de la Santé et de la Recherche Médicale (France)
European Commission
LabEx DISTALZ
Pérez-Tur, Jordi
University Children’s Hospital Basel (Suiza)
INSERM (Francia)
Lille Métropole Communauté Urbaine
Government of France (Francia)
EADB
GR@ACE
DEGESCO
EADI
GERAD
Demgene
FinnGen
ADGC
CHARGE
Holmans, Peter A. [0000-0003-0870-9412]
van der Lee, Sven J. [0000-0003-1606-8643]
Costa, Marcos R. [0000-0002-4928-2163]
Bis, Joshua C. [0000-0002-3409-1110]
Brookes, Keeley J. [0000-0003-2427-2513]
Bush, William S. [0000-0002-9729-6519]
de Witte, Lot D. [0000-0002-7235-9958]
del Ser, Teodoro [0000-0001-9806-7083]
Fox, Nick C. [0000-0002-6660-657X]
Bullido, María J. [0000-0002-6477-1117]
Goate, Alison M. [0000-0002-0576-2472]
Herrmann, Martin J. [0000-0001-9970-2122]
Jun, Gyungah R. [0000-0002-3230-8697]
Kehoe, Patrick G. [0000-0002-7542-1139]
Kosmidis, Mary H. [0000-0001-8790-1220]
Lunetta, Kathryn L. [0000-0002-9268-810X]
MacLeod, Catherine A. [0000-0002-9314-7380]
Nöthen, Markus M. [0000-0002-8770-2464]
Nordestgaard, Børge G. [0000-0002-1954-7220]
Pineda, Juan A. [0000-0002-3751-0296]
Real, Luis M. [0000-0003-4932-7429]
Reinders, Marcel J. T. [0000-0002-1148-1562]
Satizabal, Claudia L. [0000-0002-1115-4430]
Schott, Jonathan M. [0000-0003-2059-024X]
Shadrin, Alexey A. [0000-0002-7467-250X]
Farrer, Lindsay A. [0000-0001-5533-4225]
Psaty, Bruce M. [0000-0002-7278-2190]
Ikram, M. Arfan [0000-0003-0372-8585]
Pericak-Vance, Margaret A. [0000-0001-7283-8804]
Andreassen, Ole A. [0000-0002-4461-3568]
van Duijn, Cornelia M. [0000-0002-2374-9204]
van der Flier, Wiesje M. [0000-0001-8766-6224]
Molecular Neuroscience and Ageing Research (MOLAR) - Source :
- EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE 2022, ' New insights into the genetic etiology of Alzheimer's disease and related dementias ', Nature genetics, vol. 54, no. 4, pp. 412-436 . https://doi.org/10.1038/s41588-022-01024-z, Nature Genetics, 54(4), 412-436. Nature Publishing Group, Nature Genetics, 54(4), Nature genetics, 54(4), 412-436. Nature Publishing Group, Nature Genetics, 54, 4, pp. 412-436, Nature Genetics, Nature Genetics, 54, 412-436, NATURE GENETICS, r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe, instname, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, Digital.CSIC. Repositorio Institucional del CSIC, EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE 2022, ' New insights into the genetic etiology of Alzheimer's disease and related dementias ', Nature Genetics, vol. 54, no. 4, pp. 412-436 . https://doi.org/10.1038/s41588-022-01024-z, Nature genetics, 2022, ' New insights into the genetic etiology of Alzheimer's disease and related dementias ', Nature Genetics, vol. 54, no. 4, pp. 412-436 . https://doi.org/10.1038/s41588-022-01024-z, Repisalud, Instituto de Salud Carlos III (ISCIII), Nature genetics 54(4), 412-436 (2022). doi:10.1038/s41588-022-01024-z, Bellenguez, C, Küçükali, F, Jansen, I E, Kleineidam, L, Moreno-Grau, S, Amin, N, Naj, A C, Campos-Martin, R, Grenier-Boley, B, Andrade, V, Holmans, P A, Boland, A, Damotte, V, van der Lee, S J, Costa, M R, Kuulasmaa, T, Yang, Q, de Rojas, I, Bis, J C, Yaqub, A, Prokic, I, Chapuis, J, Ahmad, S, Giedraitis, V, Aarsland, D, Garcia-Gonzalez, P, Abdelnour, C, Alarcón-Martín, E, Alcolea, D, Alegret, M, Alvarez, I, Álvarez, V, Armstrong, N J, Tsolaki, A, Antúnez, C, Appollonio, I, Arcaro, M, Archetti, S, Pastor, A A, Arosio, B, Athanasiu, L, Bailly, H, Banaj, N, Baquero, M, Barral, S, Beiser, A, Nielsen, S F, Nordestgaard, B G, Sáez, M E, Frikke-Schmidt, R, EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE 2022, ' New insights into the genetic etiology of Alzheimer's disease and related dementias ', Nature Genetics, vol. 54, no. 4, pp. 412-436 . https://doi.org/10.1038/s41588-022-01024-z
- Publication Year :
- 2022
- Publisher :
- Nature Publishing Group, 2022.
-
Abstract
- 25 páginas, 6 figuras, 2 tablas<br />Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele.<br />This work was funded by a grant (EADB) from the EU Joint Programme – Neurodegenerative Disease Research. INSERM UMR1167 is also funded by the INSERM, Institut Pasteur de Lille, Lille Métropole Communauté Urbaine and French government’s LABEX DISTALZ program (development of innovative strategies for a transdisciplinary approach to AD). Full consortium acknowledgements and funding are in the Supplementary Not
- Subjects :
- tau Proteins/genetics
Alzheimer`s disease Donders Center for Medical Neuroscience [Radboudumc 1]
Neurologi
MED/03 - GENETICA MEDICA
45/43
Medizin
Stress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13]
genetics [Alzheimer Disease]
Genome-Wide Association Study
Humans
tau Proteins
Alzheimer Disease
Cognitive Dysfunction
VARIANTS
pathology [Alzheimer Disease]
Tau Proteins
Settore BIO/13 - Biologia Applicata
Cognitive Dysfunction/psychology
692/699/375/365/1283
IMPUTATION
article
1184 Genetics, developmental biology, physiology
Biología y Biomedicina / Biología
AMYLOID-BETA
Settore MED/26 - NEUROLOGIA
Neurology
psychology [Cognitive Dysfunction]
Medical Genetics
Human
Neuroscience(all)
631/208/205/2138
All institutes and research themes of the Radboud University Medical Center
SDG 3 - Good Health and Well-being
ddc:570
Genetics
Genetic Predisposition to Disease
GENOME-WIDE ASSOCIATION
METAANALYSIS
Medicinsk genetik
MED/26 - NEUROLOGIA
Alzheimer Disease/genetics
neurology
tau Protein
NECROSIS-FACTOR-ALPHA
RISK LOCI
genetics [tau Proteins]
PREDICTION MODELS
Human medicine
GENERATION
RESPONSES
Subjects
Details
- Language :
- English
- ISSN :
- 15461718 and 10614036
- Volume :
- 54
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Nature Genetics
- Accession number :
- edsair.doi.dedup.....8be61a02e6ef8a704478fd3f819f507d