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663 results on '"Spirostans"'

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1. Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions

2. Molecular Docking Studies of Spirostans as MAPK14 (P38α) Inhibitors and Their Potential Use against Cancer

3. Anticancer Effect of Ruscogenin in B(a)P-Induced Lung Cancer in Mice via Modulation of Proinflammatory Cytokines and Mitochondrial Enzymes

4. Steroidal glycosides from Ornithogalum thyrsoides bulbs and their cytotoxicity toward HL-60 human promyelocytic leukemia cells and SBC-3 human small-cell lung cancer cells.

5. Aspidiatas C and D, two new spirostanol saponins from Aspidistra triradiata and their cytotoxic activities.

6. Ruscogenin attenuates cartilage destruction in osteoarthritis through suppressing chondrocyte ferroptosis via Nrf2/SLC7A11/GPX4 signaling pathway.

7. Steroidal saponins profiling of Rohdea chinensis (Baker) N.Tanaka by high performance liquid chromatography coupled to electrospray ionization and quadrupole time-of-flight mass spectrometry.

8. Sarsasapogenin and fluticasone combination improves DNFB induced atopic dermatitis lesions in BALB/c mice

9. Protective effect of sarsasapogenin in TNBS induced ulcerative colitis in rats associated with downregulation of pro-inflammatory mediators and oxidative stress

10. Isolation and identification of hemostatic steroidal glycosides from Ypsilandra thibetica

11. Protective effects and mechanism of action of ruscogenin in a mouse model of ovalbumin-induced asthma

12. Sarsasapogenin ameliorates diabetes‐associated memory impairment and neuroinflammation through down‐regulation of <scp>PAR</scp> ‐1 receptor

13. Ruscogenin attenuates sepsis-induced acute lung injury and pulmonary endothelial barrier dysfunction via TLR4/Src/p120-catenin/VE-cadherin signalling pathway

14. Gracillin Isolated from Reineckia carnea Induces Apoptosis of A549 Cells via the Mitochondrial Pathway

15. [Protective effect of ophiopogonin D against isoproterenol-induced cardiomyocyte injury and targets]

17. Gracillin shows potent efficacy against colorectal cancer through inhibiting the STAT3 pathway

18. Ruscogenin attenuates particulate matter-induced acute lung injury in mice via protecting pulmonary endothelial barrier and inhibiting TLR4 signaling pathway

19. Sarsasapogenin Suppresses RANKL-Induced Osteoclastogenesis in vitro and Prevents Lipopolysaccharide-Induced Bone Loss in vivo

20. Rapid Detection and Characterization of Steroidal Saponins in the Root of Asparagus cochinchinensis by High-Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry

21. Gracillin inhibits apoptosis and inflammation induced by lipopolysaccharide (LPS) to alleviate cardiac injury in mice via improving miR-29a

22. Combination of Sarsasapogenin and Fluticasone attenuates ovalbumin-induced airway inflammation in a mouse asthma model

23. Potent therapeutic effects of ruscogenin on gastric ulcer established by acetic acid

24. Androgenic properties of the dietary supplement 5α-hydroxy-laxogenin

25. Ophiopogonin‑B targets PTP1B to inhibit the malignant progression of hepatocellular carcinoma by regulating the PI3K/AKT and AMPK signaling pathways

26. Isolation and Identification of Pennogenin Tetraglycoside from

27. Ruscogenin Attenuates Lipopolysaccharide-Induced Septic Vascular Endothelial Dysfunction by Modulating the miR-146a-5p/NRP2/SSH1 Axis

28. Ruscogenins Improve CD-Like Enteritis by Inhibiting Apoptosis of Intestinal Epithelial Cells and Activating Nrf2/NQO1 Pathway

29. Spirostanol Saponins from Flowers of

30. Insight into the cardiovascular mechanisms of blood pressure lowering effect of gitogenin: a steroidal saponin

31. [Effects of ophiopogonin D on fatty acid metabolic enzymes in cardiomyocytes]

32. The Role of Ophiopogonin D in Atherosclerosis: Impact on Lipid Metabolism and Gut Microbiota

33. The anti-tumor effect of OP-B on ovarian cancer in vitro and in vivo, and its mechanism: An investigation using network pharmacology-based analysis

34. Modulation of transporter activity of OATP1B1 and OATP1B3 by the major active components of Radix Ophiopogonis

35. Ophiopogonin D′-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells

36. Apigenin restores endothelial function by ameliorating oxidative stress, reverses aortic stiffening, and mitigates vascular inflammation with aging

37. Sarsasapogenin attenuates Alzheimer-like encephalopathy in diabetes

38. Sarsasapogenin restores podocyte autophagy in diabetic nephropathy by targeting GSK3β signaling pathway

39. Outlining In Vitro and In Silico Cholinesterase Inhibitory Activity of Twenty-Four Natural Products of Various Chemical Classes: Smilagenin, Kokusaginine, and Methyl Rosmarinate as Emboldening Inhibitors

40. Ophiopogonin D Inhibiting Epithelial NF-κB Signaling Pathway Protects Against Experimental Colitis in Mice

41. Ophiopogonin B induces reactive oxygen species‑dependent apoptosis through the Hippo pathway in nasopharyngeal carcinoma

42. Gitogenin suppresses lung cancer progression by inducing apoptosis and autophagy initiation through the activation of AMPK signaling

43. Ophiopogonin D Increases SERCA2a Interaction with Phospholamban by Promoting CYP2J3 Upregulation

44. Differences in the Hemolytic Behavior of Two Isomers in

45. A Total of Eight Novel Steroidal Glycosides Based on Spirostan, Furostan, Pseudofurostan, and Cholestane from the Leaves of

46. Extracts from Chinese herbs with anti-amyloid and neuroprotective activities

47. Identification and Structural Analysis of Spirostanol Saponin from Yucca schidigera by Integrating Silica Gel Column Chromatography and Liquid Chromatography/Mass Spectrometry Analysis

48. Synthesis of Thiol Derivatives of Biological Active Compounds for Nanotechnology Application

49. Effects of Shengmai San on key enzymes involved in hepatic and intestinal drug metabolism in rats

50. Ophiopogonin D promotes bone regeneration by stimulating CD31hiEMCNhi vessel formation

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