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Modulation of transporter activity of OATP1B1 and OATP1B3 by the major active components of Radix Ophiopogonis
- Source :
- Xenobiotica. 49:1221-1228
- Publication Year :
- 2019
- Publisher :
- Informa UK Limited, 2019.
-
Abstract
- Radix Ophiopogonis is often an integral part of many traditional Chinese formulas, such as Shenmai injection used to treat cardio-cerebrovascular diseases. This study aimed to investigate t...
- Subjects :
- Radix Ophiopogonis
Health, Toxicology and Mutagenesis
Active components
Pharmacology
Toxicology
030226 pharmacology & pharmacy
Biochemistry
Methylophiopogonanone B
Solute Carrier Organic Anion Transporter Family Member 1B3
03 medical and health sciences
0302 clinical medicine
Atorvastatin
Spirostans
Humans
Benzodioxoles
cardiovascular diseases
Rosuvastatin Calcium
Liver-Specific Organic Anion Transporter 1
Chemistry
Transporter
General Medicine
Saponins
Isoflavones
HEK293 Cells
Modulation
030220 oncology & carcinogenesis
Ophiopogonin D
Ranunculaceae
Subjects
Details
- ISSN :
- 13665928 and 00498254
- Volume :
- 49
- Database :
- OpenAIRE
- Journal :
- Xenobiotica
- Accession number :
- edsair.doi.dedup.....b1210d5849b7c94be1a1ad89f9690bad
- Full Text :
- https://doi.org/10.1080/00498254.2018.1493757