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1. Miniaturized Pathogen Detection System Using Magnetic Nanoparticles and Microfluidics Technology

Author

Benjamin Garlan, Amine Rabehi, Kieu Ngo, Sophie Neveu, Reza Askari Moghadam, and Hamid Kokabi

Subjects
microfluidics, pathogen detection, magnetic nanoparticle, frequency mixing method, Mechanical engineering and machinery, TJ1-1570
Abstract

Rapid detection of a biological agent is essential to anticipate a threat to the protection of biodiversity and ecosystems. Our goal is to miniaturize a magnetic pathogen detection system in order to fabricate an efficient and portable system. The detection device is based on flat, multilayer coils associated with microfluidic structures to detect magnetic nanoparticles linked to pathogen agents. One type of immunological diagnosis is based on the measurement of the magnetic sensitivity of magnetic nanoparticles (MNPs), which are markers connected to pathogens. This method of analysis involves the coupling of antibodies or antigen proteins with MNPs. Among the available magnetic techniques, the frequency mixing method has a definite advantage by making it possible to quantify MNPs. An external magnetic field composed of a low- and a high-frequency field is applied to the sample reservoir. Then, the response signal is measured and analyzed. In this paper, magnetic microcoils are implemented on a multilayer Printed Circuit Board (PCB), and a microfluidics microstructure is designed in connection with the planar coils. Simulation software, COMSOL version 5.3, provides an analytical perspective to choose the number of turns in magnetic coils and to understand the effects of changing the shape and dimensions of the microfluidics microstructure.

Published
2024
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3. Large reciprocal magneto-optical effect induced by all-dielectric resonant gratings based on a magnetic nanocomposite

Author

Laure Bsawmaii, Emilie Gamet, Yaya Lefkir, Sophie Neveu, Damien Jamon, and François Royer

Subjects
enhanced magneto-optics, all-dielectric resonant gratings, magneto-induced anisotropy, reciprocal effects, Science, Physics, QC1-999
Abstract

The beneficial combination of micro- and nano-patterned surfaces with magneto-optical materials was investigated over the recent years. Due to their resonant behavior, these structures are commonly used to enhance the non-reciprocal magneto-optical effects. In this paper, a novel kind of magneto-optical intensity effect is enhanced with an all-dielectric grating patterned on a magnetic nanocomposite layer. This nanocomposite is made of CoFe _2 O _4 nanoparticles (NPs) embedded in a silica matrix by sol–gel technique. The demonstrated magneto-optical intensity effect is reciprocal and it is observed with transverse magnetic field, for both polarization (TE and TM) and small angles of incidence. Such effect is not explained by the classical appearance of off-diagonal elements in the permittivity tensor of the magneto-optical material under magnetic field. However, it can be attributed to a magneto-induced reciprocal modification of the diagonal elements. Furthermore, this effect strongly depends on the NPs orientation inside the magneto-optical film and can originate from the magnetostrictive property of the magnetic CoFe _2 O _4 NPs.

Published
2023
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4. High Temperature Continuous Flow Syntheses of Iron Oxide Nanoflowers Using the Polyol Route in a Multi-Parametric Millifluidic Device

Author

Enzo Bertuit, Sophie Neveu, and Ali Abou-Hassan

Subjects
millifluidic device, continuous-flow syntheses, polyol route, iron oxide, magnetic nanoflowers, nanoclusters, Chemistry, QD1-999
Abstract

One of the most versatile routes for the elaboration of nanomaterials in materials science, including the synthesis of magnetic iron oxide nanoclusters, is the high-temperature polyol process. However, despite its versatility, this process still lacks reproducibility and scale-up, in addition to the low yield obtained in final materials. In this work, we demonstrate a home-made multiparametric continuous flow millifluidic system that can operate at high temperatures (up to 400 °C). After optimization, we validate its potential for the production of nanomaterials using the polyol route at 220 °C by elaborating ferrite iron oxide nanoclusters called nanoflowers (CoFe2O4, Fe3O4, MnFe2O4) with well-controlled nanostructure and composition, which are highly demanded due to their physical properties. Moreover, we demonstrate that by using such a continuous process, the chemical yield and reproducibility of the nanoflower synthesis are strongly improved as well as the possibility to produce these nanomaterials on a large scale with quantities up to 45 g per day.

Published
2021
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5. Magnetic Detection Structure for Lab-on-Chip Applications Based on the Frequency Mixing Technique

Author

Amine Rabehi, Benjamin Garlan, Stefan Achtsnicht, Hans-Joachim Krause, Andreas Offenhäusser, Kieu Ngo, Sophie Neveu, Stephanie Graff-Dubois, and Hamid Kokabi

Subjects
Lab-on-Chip, magnetic sensing, frequency mixing, superparamagnetic nanoparticles, magnetic beads, microfluidics, Chemical technology, TP1-1185
Abstract

A magnetic frequency mixing technique with a set of miniaturized planar coils was investigated for use with a completely integrated Lab-on-Chip (LoC) pathogen sensing system. The system allows the detection and quantification of superparamagnetic beads. Additionally, in terms of magnetic nanoparticle characterization ability, the system can be used for immunoassays using the beads as markers. Analytical calculations and simulations for both excitation and pick-up coils are presented; the goal was to investigate the miniaturization of simple and cost-effective planar spiral coils. Following these calculations, a Printed Circuit Board (PCB) prototype was designed, manufactured, and tested for limit of detection, linear response, and validation of theoretical concepts. Using the magnetic frequency mixing technique, a limit of detection of 15 µg/mL of 20 nm core-sized nanoparticles was achieved without any shielding.

Published
2018
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6. Structure–Property–Function Relationships of Iron Oxide Multicore Nanoflowers in Magnetic Hyperthermia and Photothermia

Author

Enzo Bertuit, Emilia Benassai, Guillaume Mériguet, Jean-Marc Greneche, Benoit Baptiste, Sophie Neveu, Claire Wilhelm, Ali Abou-Hassan, PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut des Molécules et Matériaux du Mans (IMMM), Le Mans Université (UM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Institut de recherche pour le développement [IRD] : UR206-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Physico-Chimie Curie [Institut Curie] (PCC), Institut Curie [Paris]-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), and ANR-18-CE09-0004,MicroNanoCell,Microfluidique Multi-échelle pour la Nanomédecine: de la synthèse haut débit de Nanoassemblages multifonctionnels, à leur BioTransformation et Remodelage Cellulaire dans des Conditions Biomimétiques Microfluidiques(2018)

Subjects
[PHYS]Physics [physics], magnetic nanoparticles, photothermia, Magnetic Phenomena, General Engineering, nanoflowers, General Physics and Astronomy, Hyperthermia, Induced, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, Ferric Compounds, 01 natural sciences, Ferrosoferric Oxide, nanothermal agents, 0104 chemical sciences, thermal therapies, General Materials Science, magnetic hyperthermia, multi-core iron oxides, 0210 nano-technology
Abstract

International audience; Magnetite and maghemite multi-core nanoflowers (NFs) synthesized using the modified polyol-mediated routes are to date among the most effective nano-heaters in magnetic hyperthermia (MHT). Recently, magnetite NFs have also shown high photothermal (PT) performances in the most desired second near infra-red (NIR-II) biological window making them attractive in the field of nanoparticle-activated thermal therapies. However, what makes 2 magnetic NFs efficient heating agents in both modalities still remain an open question. In this work, we investigate the role of many parameters of the polyol synthesis on the final NFs size, shape, chemical composition, number of cores and crystallinity. These nanofeatures are later correlated to the magnetic, optical and electronic properties of the NFs as well as their collective macroscopic thermal properties in MHT and PT to find relationships between their structure, properties and function. We evidence the critical role of iron(III) and heating ramps on the elaboration of well-defined NFs with high number of multi-cores. While MHT efficiency is found to be proportional to the average number of magnetic cores within the assemblies, the optical responses of the NFs and their collective photothermal properties depend directly on the mean volume of the NFs (as supported by optical cross sections numerical simulations) and strongly on the structural disorder in the NFs, rather than the stoichiometry. The concentration of defects in the nanostructures, evaluated by photoluminescence and Urbach energy (EU), evidences a switch in the optical behavior for a limit value of EU = 0.4 eV where a discontinuous transition from high to poor PT efficiency is also observed.

Published
2021

7. All-Fiber Magneto-Optical Effect Using Nanoparticles Doped Sol-Gel Thin Film Deposited Within Microstructured Fibers

Author

Alexis Dufour, Stéphanie Reynaud, Sylvain Girard, Damien Jamon, Sophie Neveu, Laure Bsawmaii, Emmanuel Marin, Francois Royer, Laboratoire Hubert Curien [Saint Etienne] (LHC), Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS)-Institut d'Optique Graduate School (IOGS), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), and Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Materials science, Optical fiber, Physics::Optics, Nanoparticle, 02 engineering and technology, engineering.material, 7. Clean energy, law.invention, symbols.namesake, 020210 optoelectronics & photonics, Coating, law, Faraday effect, 0202 electrical engineering, electronic engineering, information engineering, Fiber, Thin film, ComputingMilieux_MISCELLANEOUS, Sol-gel, [PHYS]Physics [physics], business.industry, Atomic and Molecular Physics, and Optics, Core (optical fiber), engineering, symbols, Optoelectronics, business
Abstract

An innovative functionalization method allowing to greatly increase the Faraday effect of microstructured silica-based optical fibers is described. This method relies on the coating of a sol-gel thin film doped with magnetic field sensitive cobalt ferrite nanoparticles around the suspended core of the fiber. By varying the functionalization process parameters, both the film thickness and nanoparticle concentrations can be tailored to optimize the fiber magneto-optical response by a proper adjustment the interaction between the guided mode and the composite film. Experimental measurements in an all-fiber configuration on several samples diversely functionalized show a significant polar magneto-optical effect. A polarization rotation as large as 10° has been measured at 1550 nm when the most efficiently functionalized fiber is located inside a 0.7 cm air gap electromagnet at 1 Tesla. The present method and the developed all-fiber components are very promising candidates for the design of fiber-based sensors of magnetic fields.

Published
2021

9. Deep‐UV Lithography of Nanocomposite Thin Films into Magnetooptical Gratings with Submicron Periodicity

Author

Francois Royer, Dominique Berling, Damien Jamon, Sophie Neveu, Olivier Soppera, Loïc Vidal, Clémentine Bidaud, Emilie Gamet, Institut de Science des Matériaux de Mulhouse (IS2M), Centre National de la Recherche Scientifique (CNRS)-Matériaux et nanosciences d'Alsace (FMNGE), Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), Laboratoire Hubert Curien [Saint Etienne] (LHC), Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS)-Institut d'Optique Graduate School (IOGS), Institut de Chimie des Sufaces et Interfaces (ICSI), Centre National de la Recherche Scientifique (CNRS), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et Nanosciences Grand-Est (MNGE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Institut d'Optique Graduate School (IOGS)-Université Jean Monnet - Saint-Étienne (UJM)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), and Jamon, Damien

Subjects
Materials science, 02 engineering and technology, 01 natural sciences, [PHYS] Physics [physics], Analytical Chemistry, law.invention, symbols.namesake, law, [CHIM] Chemical Sciences, 0103 physical sciences, Faraday effect, [CHIM]Chemical Sciences, Physical and Theoretical Chemistry, Lithography, ComputingMilieux_MISCELLANEOUS, [PHYS]Physics [physics], 010302 applied physics, Nanocomposite, business.industry, Organic Chemistry, Nanocomposite thin films, 021001 nanoscience & nanotechnology, symbols, Optoelectronics, Photolithography, 0210 nano-technology, business
Abstract

International audience

Published
2020

10. Small CoFe2O4 magnetic nanoparticles in ferrofluids, influence of the synthesis on the magnetic anisotropies

Author

Marie-Anne Arrio, Sophie Neveu, Philippe Ohresser, Véronica Gavrilov, Amélie Juhin, Philippe Sainctavit, Niéli Daffé, Fadi Choueikani, Vincent Dupuis, Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Institut de recherche pour le développement [IRD] : UR206-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), and Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[PHYS]Physics [physics], 010302 applied physics, Ferrofluid, Materials science, Absorption spectroscopy, Magnetic circular dichroism, chemistry.chemical_element, Nanoparticle, 02 engineering and technology, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 01 natural sciences, Electronic, Optical and Magnetic Materials, Magnetic anisotropy, chemistry, Interstitial defect, 0103 physical sciences, Physical chemistry, Magnetic nanoparticles, 0210 nano-technology, Cobalt
Abstract

The magnetic properties of cobalt ferrites nanoparticles prepared using three different processes (thermal decomposition, polyol and co-precipitation synthesis routes) are investigated by X-ray Absorption Spectroscopy and X-ray Magnetic Circular Dichroism. The repartition of cobalt and iron ions amongst the interstitial sites of the spinel structure is determined and correlated with their magnetic properties. The study reports on the influence of the synthesis method on the crystallographic order within a nanoparticle, and hence, on the magnetic anisotropy.

Published
2019

11. Self-biased magneto-optical films based on CoFe 2 O 4 –silica nanocomposite

Author

M.-F. Blanc-Mignon, Y. Lefkir, Sophie Neveu, Francois Royer, Damien Jamon, Fadi Choueikani, Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), Laboratoire Hubert Curien [Saint Etienne] (LHC), Institut d'Optique Graduate School (IOGS)-Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), and Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS)-Institut d'Optique Graduate School (IOGS)

Subjects
Materials science, Physics::Optics, General Physics and Astronomy, Nanoparticle, 02 engineering and technology, Substrate (electronics), engineering.material, 7. Clean energy, 01 natural sciences, Condensed Matter::Materials Science, symbols.namesake, Coating, 0103 physical sciences, Faraday effect, Figure of merit, Thin film, ComputingMilieux_MISCELLANEOUS, 010302 applied physics, [PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics], Birefringence, business.industry, 021001 nanoscience & nanotechnology, Magnetic anisotropy, engineering, symbols, Optoelectronics, 0210 nano-technology, business
Abstract

Composite thin films made of cobalt ferrite nanoparticles embedded in silica/zirconia sol-gel matrix are presented, and their versatility is illustrated through the impact of the nanoparticle features on the films’ final properties. The intrinsic magneto-optical potentiality of the nanoparticles is especially given by a peak around 1550 nm in the spectra of both the Faraday rotation and the magneto-optical figure of merit. These nanoparticles are inserted in the liquid preparation of a sol-gel host matrix, which is coated on a glass substrate at soft temperature. SEM and optical analysis show the absence of nanoparticle aggregates and defects into thin films and prove the ability of these films to be used as a guiding layer for photonic integration. The dispersion in the host matrix and the integration on a substrate do not affect the merit factor of the material. The specific Faraday rotation of the films is about 300 ° / cm for a volume fraction of nanoparticles of 1.5%, and it possesses a hysteresis loop. Its dependence on the nanoparticle mean size offers the possibility to achieve self-biased behavior. In addition, a magnetic field applied during the coating promotes an alignment of the magnetic easy axis of the nanoparticles along a preferential direction. It allows increasing even more the remanent magneto-optical effect and also reducing the birefringence and reaching a TE/TM phase matching of the film guided modes. It gives a way to tune these two parameters that play a crucial role in magneto-optical devices.

Published
2021

12. Photocrosslinking and photopatterning of magneto-optical nanocomposite sol-gel thin film under deep-UV irradiation

Author

C. Bidaud, Damien Jamon, Francois Royer, Dominique Berling, Sophie Neveu, Emilie Gamet, Olivier Soppera, Gestionnaire, Hal Sorbonne Université, Institut de Science des Matériaux de Mulhouse (IS2M), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et Nanosciences Grand-Est (MNGE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Hubert Curien [Saint Etienne] (LHC), Institut d'Optique Graduate School (IOGS)-Université Jean Monnet - Saint-Étienne (UJM)-Centre National de la Recherche Scientifique (CNRS), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Matériaux et nanosciences d'Alsace (FMNGE), Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), and Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS)-Institut d'Optique Graduate School (IOGS)

Subjects
Materials science, Science, Radical polymerization, Nanoparticle, Nanotechnology, 02 engineering and technology, 010402 general chemistry, Methacrylate, 01 natural sciences, Article, [CHIM] Chemical Sciences, [CHIM]Chemical Sciences, Thin film, Sol-gel, Multidisciplinary, Nanocomposite, Synthesis and processing, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Photopolymer, Optical materials, Magnetic nanoparticles, Medicine, 0210 nano-technology, Materials for optics
Abstract

This paper is aimed at investigating the process of photocrosslinking under Deep-UV irradiation of nanocomposite thin films doped with cobalt ferrite magnetic nanoparticles (MNPs). This material is composed of a hybrid sol–gel matrix in which MNP can be introduced with high concentrations up to 20 vol%. Deep-UV (193 nm) is not only interesting for high-resolution patterning but we also show an efficient photopolymerization pathway even in the presence of high concentration of MNPs. In this study, we demonstrate that the photocrosslinking is based on the free radical polymerization of the methacrylate functions of the hybrid precursor. This process is initiated by Titanium-oxo clusters. The impact of the nanoparticles on the photopolymerization kinetic and photopatterning is investigated. We finally show that the photosensitive nanocomposite is suitable to obtain micropatterns with sub-micron resolution, with a simple and versatile process, which opens many opportunities for fabrication of miniaturized magneto-optical devices for photonic applications.

Published
2021

13. AI-driven quantification, staging and outcome prediction of COVID-19 pneumonia

Author

Nikos Paragios, Chahinez Hani, Maxime Barat, Hasmik Koulakian, Stéphane Tran Ba, Eric Deutsch, Trieu Nghi Hoang-Thi, Ahmed Mekki, Téodor Grand, Severine Dangeard, Fabrice Andre, Souhail Bennani, Pierre Yves Brillet, Laure Fournier, A. Lombard, Robert Carlier, Hippolyte Monnier, Jules Gregory, Maria Vakalopoulou, Enzo Battistella, Antoine Khalil, Stefany El Hajj, Marie-Pierre Revel, Elyas Mahdjoub, Sophie Neveu, Stergios Christodoulidis, Nara Halm, Alienor Campredon, Florian Bompard, G. Freche, Valérie Bousson, Enora Guillo, Guillaume Chassagnon, Yann Nguyen, Ines Saab, CCSD, Accord Elsevier, Service de Radiologie [CHU Cochin], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Mathématiques et Informatique pour la Complexité et les Systèmes (MICS), CentraleSupélec-Université Paris-Saclay, Institut Gustave Roussy (IGR), TheraPanacea [Paris], Biomarqueurs prédictifs et nouvelles stratégies moléculaires en thérapeutique anticancéreuse (U981), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Radiothérapie Moléculaire et Innovation Thérapeutique (RaMo-IT), Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Hôpital Beaujon [AP-HP], Département de Radiologie [Bichat] (DR- Bichat), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Service de radiologie [Avicenne], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Avicenne [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Sorbonne Paris Nord, AP-HP - Hôpitaux Universitaires Paris Seine-Saint-Denis (GHU 93), Hôpital Lariboisière-Fernand-Widal [APHP], Hôpital Ambroise Paré [AP-HP], OPtimisation Imagerie et Santé (OPIS), Inria Saclay - Ile de France, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre de vision numérique (CVN), Institut National de Recherche en Informatique et en Automatique (Inria)-CentraleSupélec-Université Paris-Saclay-CentraleSupélec-Université Paris-Saclay, Hôpital Beaujon, AP-HP - Hôpital Bichat - Claude Bernard [Paris], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)

Subjects
Staging, Disease, 030218 nuclear medicine & medical imaging, law.invention, [INFO.INFO-AI]Computer Science [cs]/Artificial Intelligence [cs.AI], 0302 clinical medicine, law, Medicine, Biomarker discovery, [SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases, [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Radiological and Ultrasound Technology, Prognosis, Intensive care unit, Computer Graphics and Computer-Aided Design, 3. Good health, Drug development, Radiology Nuclear Medicine and imaging, Disease Progression, Radiographic Image Interpretation, Computer-Assisted, Computer Vision and Pattern Recognition, [INFO.INFO-AI] Computer Science [cs]/Artificial Intelligence [cs.AI], medicine.medical_specialty, Ensemble methods, Pneumonia, Viral, Health Informatics, Article, 03 medical and health sciences, Artificial Intelligence, Medical imaging, Humans, Radiology, Nuclear Medicine and imaging, Medical physics, business.industry, SARS-CoV-2, COVID-19, Deep learning, Triage, Ensemble learning, COVID 19 pneumonia, Anticipation (artificial intelligence), Neural Networks, Computer, business, Artifial intelligence, 030217 neurology & neurosurgery, Biomarkers, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

Highlights • An algorithm for automatic Covid-19 quantification based on 2D & 3D deep convolutional neural networks is presented. • A Covid-19-specific holistic, highly compact multi-omics signature integrating imaging/clinical/ biological data and associated comorbidities for automatic patient staging is presented and evaluated. • Short and Long-term prognosis for clinical resources optimization offering alternative/complementary means to facilitate triage for Covid-19 • Clinically-relevant quantification and staging tool validated by comparison with clinical experts is reported., Graphical abstract, Coronavirus disease 2019 (COVID-19) emerged in 2019 and disseminated around the world rapidly. Computed tomography (CT) imaging has been proven to be an important tool for screening, disease quantification and staging. The latter is of extreme importance for organizational anticipation (availability of intensive care unit beds, patient management planning) as well as to accelerate drug development through rapid, reproducible and quantified assessment of treatment response. Even if currently there are no specific guidelines for the staging of the patients, CT together with some clinical and biological biomarkers are used. In this study, we collected a multi-center cohort and we investigated the use of medical imaging and artificial intelligence for disease quantification, staging and outcome prediction. Our approach relies on automatic deep learning-based disease quantification using an ensemble of architectures, and a data-driven consensus for the staging and outcome prediction of the patients fusing imaging biomarkers with clinical and biological attributes. Highly promising results on multiple external/independent evaluation cohorts as well as comparisons with expert human readers demonstrate the potentials of our approach.

Published
2021

14. Incidental diagnosis of Covid-19 pneumonia on chest computed tomography

Author

Guillaume Chassagnon, Severine Dangeard, Sophie Neveu, Marie-Pierre Revel, Ines Saab, Souhail Bennani, Mickael Tordjman, Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), and Université de Paris (UP)

Subjects
Male, [SDV]Life Sciences [q-bio], Disease, 030218 nuclear medicine & medical imaging, 0302 clinical medicine, Cumulative incidence, Fatigue, Aged, 80 and over, COVID-19, Coronavirus disease 2019, Radiological and Ultrasound Technology, Reverse Transcriptase Polymerase Chain Reaction, Medical record, General Medicine, Middle Aged, Incidental findings, CT, computed tomography, 3. Good health, medicine.anatomical_structure, Radiology Nuclear Medicine and imaging, 030220 oncology & carcinogenesis, CRP, C-reactive protein, Female, Radiography, Thoracic, Radiology, medicine.symptom, Coronavirus Infections, Adult, RT-PCR, reverse-transcriptase polymerase chain reaction, Paris, medicine.medical_specialty, Pneumonia, Viral, Asymptomatic, Article, Betacoronavirus, Multidetector, 03 medical and health sciences, White blood cell, Multidetector Computed Tomography, medicine, Humans, Radiology, Nuclear Medicine and imaging, COVID-19 pneumonia, Pandemics, Retrospective Studies, Asymptomatic Diseases, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, business.industry, COVID-19, computed tomography, Retrospective cohort study, GGO, ground glass opacities, medicine.disease, Pneumonia, business
Abstract

Purpose The purpose of this study was to determine the prevalence and imaging characteristics of incidentally diagnosed COVID-19 pneumonia on computed tomography (CT). Materials and methods This retrospective study was conducted between March 20th and March 31st, 2020 at Cochin hospital, Paris France. Thoracic CT examinations of all patients referred for another reason than a suspicion of SARS-CoV-2 infection were reviewed. CT images were analyzed by a chest radiologist to confirm the presence of findings consistent with COVID-19 pneumonia and quantify disease extent. Clinical and biological data (C-reactive protein serum level [CRP] and white blood cell count) of patients with CT findings suggestive for COVID-19 pneumonia were retrieved from the electronic medical chart. Results During the study period, among 205 diagnostic CT examinations, six examinations (6/205, 3%) in 6 different patients (4 men, 2 women; median age, 57 years) revealed images highly suggestive of COVID-19 pneumonia. The final diagnosis was confirmed by RT-PCR. Three inpatients were suspected of extra thoracic infection whereas three outpatients were either fully asymptomatic or presented with fatigue only. All had increased CRP serum level and lymphopenia. Disease extent on CT was mild to moderate in 5/6 patients (83%) and severe in 1/6 patient (17%). Conclusion Cumulative incidence of fortuitous diagnosis if COVID-19 pneumonia did not exceed 3% during the highest pandemic phase and was predominantly associated with limited lung involvement.

Published
2020

15. Bad neighbour, good neighbour: how magnetic dipole interactions between soft and hard ferrimagnetic nanoparticles affect macroscopic magnetic properties in ferrofluids

Author

Vincent Dupuis, Yohan Guyodo, Philippe Sainctavit, Véronica Gavrilov, Niéli Daffé, Jovana Zečević, Kalliopi N. Trohidou, Claire Carvallo, Dario Taverna, Nadejda Bouldi, M. Vasilakaki, Amélie Juhin, Marcin Sikora, Sophie Neveu, Fadi Choueikani, Mauro Rovezzi, Johannes D. Meeldijk, Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Institut de recherche pour le développement [IRD] : UR206-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Utrecht University [Utrecht], National Center for Scientific Research 'Demokritos' (NCSR), AGH University of Science and Technology [Krakow, PL] (AGH UST), Université Grenoble Alpes (UGA), Institut de Physique du Globe de Paris (IPGP), Institut national des sciences de l'Univers (INSU - CNRS)-IPG PARIS-Université de La Réunion (UR)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institute of Nanoscience and Nanotechnology 'Demokritos' [Greece] (INN), Observatoire des Sciences de l'Univers de Grenoble (OSUG ), Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA), FAME - Fermentation Advances and Microbial Engineering (TBI-FAME), Toulouse Biotechnology Institute (TBI), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), ANR-11-IDEX-0004,SUPER,Sorbonne Universités à Paris pour l'Enseignement et la Recherche(2011), European Project: 731976,Magenta, Minéralogie et magnétisme de basses dimensionnalités [IMPMC] (IMPMC_MIMABADI), Muséum national d'Histoire naturelle (MNHN)-Institut de recherche pour le développement [IRD] : UR206-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Muséum national d'Histoire naturelle (MNHN)-Institut de recherche pour le développement [IRD] : UR206-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA)-Météo-France, Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut de Physique du Globe de Paris (IPGP (UMR_7154)), and Institut national des sciences de l'Univers (INSU - CNRS)-Université de La Réunion (UR)-Institut de Physique du Globe de Paris (IPG Paris)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)

Subjects
[PHYS]Physics [physics], Ferrofluid, Materials science, Condensed matter physics, Nanoparticle, 02 engineering and technology, 021001 nanoscience & nanotechnology, 01 natural sciences, Magnetic field, Physics::Fluid Dynamics, Ferrimagnetism, 0103 physical sciences, Magnetic nanoparticles, [CHIM]Chemical Sciences, General Materials Science, [PHYS.COND]Physics [physics]/Condensed Matter [cond-mat], 010306 general physics, 0210 nano-technology, Spectroscopy, Nanoscopic scale, Magnetic dipole
Abstract

International audience; Fluids responding to magnetic fields (ferrofluids) offer a scene with no equivalent in nature to explore long-range magnetic dipole interactions. Here, we studied the very original class of binary ferrofluids, embedding soft and hard ferrimagnetic nanoparticles. We used a combination of x-ray magnetic spectroscopy measurements supported by multi-scale experimental techniques and Monte-Carlo simulations to unveil the origin of the emergent macroscopic magnetic properties of the binary mixture. We found that the association of soft and hard magnetic nanoparticles in the fluid has a considerable influence on their inherent magnetic properties. While the ferrofluid remains in a single phase, magnetic interactions at the nanoscale between both types of particles induce a modification of their respective coercive fields. By connecting the microscopic properties of binary ferrofluids containing small particles, our findings lay the groundwork for the manipulation of magnetic interactions between particles at the nanometer scale in magnetic liquids.

Published
2020

16. Holistic AI-Driven Quantification, Staging and Prognosis of COVID-19 Pneumonia

Author

Ines Saab, Gael Freche, Jules Gregory, Nara Halm, Enzo Battistella, Stéphane Tran Ba, Hasmik Koulakian, Fabrice Andre, Hippolyte Monnier, A. Lombard, Valérie Bousson, Marie-Pierre Revel, Laure Fournier, Nikos Paragios, Elyas Mahdjoub, Alienor Campredon, Severine Dangeard, Stefany El Hajj, Souhail Bennani, Sophie Neveu, Trieu-Nghi Hoang-Thi, Maria Vakalopoulou, Chahinez Hani, Florian Bompard, Eric Deutsch, Guillaume Chassagnon, Stergios Christodoulidis, Téodor Grand, Antoine Khalil, Pierre-Yves Brillet, and Enora Guillo

Subjects
Mechanical ventilation, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), business.industry, medicine.medical_treatment, Economic shortage, medicine.disease, Patient management, Term (time), Pneumonia, Intensive care, medicine, Intensive care medicine, business, Outcome prediction
Abstract

Improving screening, discovering therapies, developing a vaccine and performing staging and prognosis are decisive steps in addressing the COVID-19 pandemic. Staging and prognosis are especially crucial for organizational anticipation (intensive-care bed availability, patient management planning) and accelerating drug development; through rapid, reproducible and quantified response-to-treatment assessment. In this letter, we report on an artificial intelligence solution for performing automatic staging and prognosis based on imaging, clinical, comorbidities and biological data. This approach relies on automatic computed tomography (CT)-based disease quantification using deep learning, robust data-driven identification of physiologically-inspired COVID-19 holistic patient profiling, and strong, reproducible staging/outcome prediction with good generalization properties using an ensemble of consensus methods. Highly promising results on multiple independent external evaluation cohorts along with comparisons with expert human readers demonstrate the potentials of our approach. The developed solution offers perspectives for optimal patient management, given the shortage of intensive care beds and ventilators1, 2, along with means to assess patient response to treatment.

Published
2020

17. Enhanced magneto-optical response with a 1D resonant grating for sensing applications

Author

Laure Bsawmaii, François Royer, Sophie Neveu, Emilie Gamet, Damien Jamon, Laboratoire Hubert Curien [Saint Etienne] (LHC), Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS)-Institut d'Optique Graduate School (IOGS), Laboratoire Telecom Claude Chappe (LT2C), Université Jean Monnet [Saint-Étienne] (UJM)-Ecole d'ingenieurs Telecom Saint Etienne, PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)

Subjects
[PHYS]Physics [physics], Waveguide (electromagnetism), Materials science, Sensing applications, business.industry, Physics::Optics, 02 engineering and technology, Dielectric, Grating, 021001 nanoscience & nanotechnology, 01 natural sciences, Magneto optical, Magnetic field, 010309 optics, High transmission, 0103 physical sciences, Optoelectronics, Physics::Atomic Physics, 0210 nano-technology, business, ComputingMilieux_MISCELLANEOUS
Abstract

Significant enhancement of the longitudinal magneto-optical effect accompanied with high transmission was demonstrated by experimental measurements and confirmed by numerical simulations for small angles of incidence. The work was led with a subwavelength resonant structure consisting of a 1D dielectric grating structured on top of a magneto-optical waveguide. The simplicity of the fabricated structure associated to the significant achieved magneto-optical effect, make the structure a promising tool for applications like magnetic field sensors or in non-destructive testing.

Published
2020

18. Longitudinal magneto-optical effect enhancement with high transmission through a 1D all-dielectric resonant guided mode grating

Author

Sophie Neveu, Emilie Gamet, Francois Royer, Damien Jamon, Laure Bsawmaii, Laboratoire Hubert Curien [Saint Etienne] (LHC), Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS)-Institut d'Optique Graduate School (IOGS), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), and Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[PHYS]Physics [physics], Materials science, business.industry, Guided-mode resonance, Physics::Optics, 02 engineering and technology, Dielectric, Grating, 021001 nanoscience & nanotechnology, Polarization (waves), 01 natural sciences, Surface plasmon polariton, Atomic and Molecular Physics, and Optics, Magneto optical, Magnetic field, 010309 optics, Optics, 0103 physical sciences, Transmittance, 0210 nano-technology, business, ComputingMilieux_MISCELLANEOUS
Abstract

A significant enhancement of the longitudinal magneto-optical effect is demonstrated numerically and experimentally in transmission, and for small angles of incidence, through a subwavelength resonant structure consisting of a dielectric grating on top of a magneto-optical waveguide. The enhanced polarization rotation is associated with a high transmittance. These low footprint devices may thus be suitable for applications like magnetic field sensors or in non-destructive testing.

Published
2020

19. Micro-structured optical fiber functionalization with magnetic nanoparticles doped sol-gel matrix: application to an all-fiber magnetic field sensor

Author

Sylvain Girard, Frédéric Royer, A. Dufour, L. Bsawmaii, Sophie Neveu, Emmanuel Marin, Stéphanie Reynaud, Damien Jamon, Laboratoire Hubert Curien [Saint Etienne] (LHC), Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS)-Institut d'Optique Graduate School (IOGS), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), and Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Optical fiber, Materials science, Physics::Optics, 02 engineering and technology, engineering.material, 01 natural sciences, law.invention, 010309 optics, Condensed Matter::Materials Science, symbols.namesake, Coating, law, 0103 physical sciences, Faraday effect, Fiber, Thin film, ComputingMilieux_MISCELLANEOUS, [PHYS]Physics [physics], business.industry, 021001 nanoscience & nanotechnology, Condensed Matter::Soft Condensed Matter, Core (optical fiber), engineering, symbols, Optoelectronics, Surface modification, Magnetic nanoparticles, 0210 nano-technology, business
Abstract

The functionalization of micro-structured optical fibers can bring new applications for conventional fibers. We present a magneto-optic sensor based on the Faraday effect, through magnetic nanoparticles doped sol-gel thin film coating the fiber core.

Published
2020

20. Magnetic nanocomposite films with photo-patterned 1D grating on top enable giant magneto-optical intensity effects

Author

Laure Bsawmaii, Emilie Gamet, Sophie Neveu, Damien Jamon, and François Royer

Subjects
Electronic, Optical and Magnetic Materials
Abstract

The enhancement of magneto-optical (MO) effects in planar devices is commonly obtained through the combination of a plasmonic resonance and a MO material, or through the microstructuration of such materials. However, the devices often suffer from weak optical signal, or require fastidious lithography processes. We present a much simpler device made of a photoresist 1D grating processed on a MO composite planar waveguide. This latter is formed by magnetic nanoparticles embedded in a silica matrix. Such all-dielectric device produces much higher Q-factor resonances, which finally result in giant MO intensity effects. Their magnitude combined with the ability of the device to be processed on large scale and various substrates, are very promising for a wide range of sensing applications.

Published
2022

21. Enhancement of Both Faraday and Kerr Effects with an All-Dielectric Grating Based on a Magneto-Optical Nanocomposite Material

Author

Yves Jourlin, Damien Jamon, Emilie Gamet, Sophie Neveu, Francois Royer, Bobin Varghese, Laboratoire Hubert Curien [Saint Etienne] (LHC), Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS)-Institut d'Optique Graduate School (IOGS), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), and Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Materials science, General Chemical Engineering, Physics::Optics, 02 engineering and technology, Dielectric, Grating, 01 natural sciences, Article, law.invention, 010309 optics, symbols.namesake, law, 0103 physical sciences, Faraday effect, Faraday cage, QD1-999, ComputingMilieux_MISCELLANEOUS, Photonic crystal, [PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics], business.industry, General Chemistry, 021001 nanoscience & nanotechnology, Polarization (waves), Magnetic field, Chemistry, symbols, Optoelectronics, 0210 nano-technology, business, Excitation
Abstract

We report on the design, fabrication, and characterization of an all-dielectric one-dimensional (1D) resonant device formed by a silicon nitride grating impregnated by a low-index magneto-optical silica-type matrix. This impregnation is realized through the dipping of the 966 nm periodic template in a sol–gel solution previously doped with CoFe2O4 nanoparticles, and able to fill the grating slits. By a proper adjustment of the geometrical parameters of such a photonic crystal membrane, simultaneous excitation of transverse electric (TE) and transverse magnetic (TM) polarization resonances is nearly achieved at 1570 nm. This TE/TM phase-matching situation leads to a fivefold enhancement of the Faraday effect in the resonance area with an increased merit factor of 0.32°. Moreover, the device demonstrates its ability to enhance longitudinal and transverse Kerr effects for the other directions of the applied magnetic field. Taking benefits from the ability of the nanocomposite material to be processed on photonic platforms, and despite its quite low magneto-optical activity compared to classical magnetic materials, this work proves that an all-dielectric 1D device can produce a high magneto-optical sensitivity to every magnetic field directions.

Published
2019

22. Synthesis and study of γ-Fe 2 O 3 and CoFe 2 O 4 based ferrofluids by means of spectroscopic Mueller matrix ellipsometry

Author

Damien Jamon, Enric Garcia-Caurel, M. Stchakovsky, Yann Battie, Sophie Neveu, Laboratoire de Chimie et Physique - Approche Multi-échelle des Milieux Complexes (LCP-A2MC), Université de Lorraine (UL), HORIBA France SAS [Longjumeau], HORIBA Scientific [France], PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Hubert Curien [Saint Etienne] (LHC), Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS)-Institut d'Optique Graduate School (IOGS), Laboratoire de physique des interfaces et des couches minces [Palaiseau] (LPICM), and École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Ferrofluid, Materials science, Nanoparticle, Maghemite, 02 engineering and technology, engineering.material, 01 natural sciences, 010309 optics, Ferrimagnetism, 0103 physical sciences, Materials Chemistry, Mueller calculus, Electrical and Electronic Engineering, Anisotropy, Instrumentation, ComputingMilieux_MISCELLANEOUS, [PHYS]Physics [physics], Condensed matter physics, Process Chemistry and Technology, 021001 nanoscience & nanotechnology, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Ferromagnetism, Effective medium approximations, engineering, 0210 nano-technology
Abstract

Ferrofluids are colloidal suspensions generally composed of ferromagnetic or ferrimagnetic nanoparticles (NPs). In the present study, the authors have focused on the ellipsometric characterization of two types of ferrofluids: one constituting maghemite (γ-Fe2O3) NPs and the other cobalt ferrite (CoFe2O4) NPs. The optical properties of the NPs are extracted from the ellipsometric spectra by using the Maxwell–Garnett effective medium approximations. As expected, Mueller matrix measurements reveal that the ferrofluid becomes anisotropic under the influence of a magnetic field. The authors correlate this anisotropy to the preferential orientation of NPs along the magnetic field.Ferrofluids are colloidal suspensions generally composed of ferromagnetic or ferrimagnetic nanoparticles (NPs). In the present study, the authors have focused on the ellipsometric characterization of two types of ferrofluids: one constituting maghemite (γ-Fe2O3) NPs and the other cobalt ferrite (CoFe2O4) NPs. The optical properties of the NPs are extracted from the ellipsometric spectra by using the Maxwell–Garnett effective medium approximations. As expected, Mueller matrix measurements reveal that the ferrofluid becomes anisotropic under the influence of a magnetic field. The authors correlate this anisotropy to the preferential orientation of NPs along the magnetic field.

Published
2019

23. Full experimental determination of the optical and magneto-optical characteristics of a hybrid glass waveguide covered by a magnetic nanoparticles doped sol-gel layer

Author

Elodie Jordan, Jean-Emmanuel Broquin, Francois Royer, Damien Jamon, Jean-Philippe Garayt, Elise Ghibaudo, Sophie Neveu, Laboratoire Hubert Curien [Saint Etienne] (LHC), Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS)-Institut d'Optique Graduate School (IOGS), Institut de Microélectronique, Electromagnétisme et Photonique - Laboratoire d'Hyperfréquences et Caractérisation (IMEP-LAHC ), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Liquides Ioniques et Interfaces Chargées (LI2C), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), and Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Materials science, Optical isolator, Physics::Optics, 02 engineering and technology, magneto-optical isolator, 01 natural sciences, Waveguide (optics), law.invention, 010309 optics, symbols.namesake, law, 0103 physical sciences, Faraday effect, Absorption (electromagnetic radiation), business.industry, Isolator, Doping, 021001 nanoscience & nanotechnology, Atomic and Molecular Physics, and Optics, [SPI.ELEC]Engineering Sciences [physics]/Electromagnetism, integrated optics, symbols, [SPI.OPTI]Engineering Sciences [physics]/Optics / Photonic, Magnetic nanoparticles, Optoelectronics, 0210 nano-technology, business, Refractive index
Abstract

International audience; Optical waveguides, where propagating modes inter- act with a magnetized magneto-optical layer, show non-reciprocal properties such as mode conversion, phase shift and absorption. These properties are essential in order to make an efficient integrated isolator. In this paper, we explain how a well-calibrated polarimetric setup can be used to measure all the magneto-optical characteristics of a waveguide, in order to advance towards well- controlled integrated optical isolators.

Published
2019

24. Determining extent of COVID-19 pneumonia on CT based on biological variables

Author

Fadila Mihoubi, Laure Fournier, Ahmed Mekki, Rahul D. Mali, Hippolyte Monnier, Nicolas Carlier, Jonathan Marey, Sophie Neveu, Mickael Tordjman, Marie-Pierre Revel, Jean-Luc Drapé, Robert-Yves Carlier, Guillaume Chassagnon, New York University School of Medicine, and NYU System (NYU)

Subjects
Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Correlation coefficient, Coronavirus disease 2019 (COVID-19), [SDV]Life Sciences [q-bio], Pneumonia, Viral, Bivariate analysis, Sensitivity and Specificity, Severity of Illness Index, Gastroenterology, Fibrin Fibrinogen Degradation Products, Correlation, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Severity of illness, Leukocytes, Humans, Medicine, Lymphocyte Count, 030212 general & internal medicine, Aged, Retrospective Studies, Original Research, Aged, 80 and over, L-Lactate Dehydrogenase, biology, SARS-CoV-2, business.industry, C-reactive protein, COVID-19, Retrospective cohort study, CT-scan, Middle Aged, medicine.disease, 3. Good health, Pneumonia, C-Reactive Protein, 030228 respiratory system, biology.protein, Female, France, Tomography, X-Ray Computed, business, Biomarkers, Coronavirus 2019 disease
Abstract

Introduction Covid-19 pneumonia CT extent correlates well with outcome including mortality. However, CT is not widely available in many countries. This study aimed to explore the relationship between Covid-19 pneumonia CT extent and blood tests variations. The objective was to determine for the biological variables correlating with disease severity the cut-off values showing the best performance to predict the parenchymal extent of the pneumonia. Methods Bivariate correlations were calculated between biological variables and grade of disease extent on CT. Receiving Operating Characteristic curve analysis determined the best cutoffs for the strongest correlated biological variables. The performance of these variables to predict mild (50% of parenchyma involved) was evaluated. Results Correlations between biological variables and disease extent was evaluated in 168 patients included in this study. LDH, lymphocyte count and CRP showed the strongest correlations (with 0.67, −0.41 and 0.52 correlation coefficient, respectively). Patients were split into a training and a validation cohort according to their centers. If one variable was above/below the following cut-offs, LDH>380, CRP>80 or lymphocyte count, Highlights • Patients with mild respiratory symptoms are not necessarily referred for CT when they are diagnosed with SARS-CoV2 infection. • Previous studies demonstrated than extent of Covid-19 pneumonia on CT is related to patients' outcome. • LDH combined with CRP and lymphocyte count, help predicting parenchymal extent of the pneumonia when CT-scan is not available.

Published
2020

25. Large Spectral Modification of the Faraday Effect of 3D SiO2/CoFe2O4 Magneto-Photonic Crystals

Author

Damien Jamon, Francois Royer, Jean Jacques Rousseau, Elie Abou-Diwan, Marie-Françoise Blanc-Mignon, Sophie Neveu, and Renata Kekesi

Subjects
Materials science, business.industry, Biomedical Engineering, Bioengineering, 02 engineering and technology, General Chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 01 natural sciences, law.invention, 010309 optics, symbols.namesake, Optics, law, 0103 physical sciences, Faraday effect, symbols, Optoelectronics, General Materials Science, 0210 nano-technology, business, Faraday rotator, Magneto, Photonic crystal
Published
2016

26. Magnetic anisotropies and cationic distribution in CoFe2O4 nanoparticles prepared by co-precipitation route: Influence of particle size and stoichiometry

Author

Niéli Daffé, Philippe Ohresser, Amélie Juhin, Philippe Sainctavit, Marie-Anne Arrio, Vincent Dupuis, Sophie Neveu, Fadi Choueikani, Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de recherche pour le développement [IRD] : UR206-Centre National de la Recherche Scientifique (CNRS), Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de recherche pour le développement [IRD] : UR206-Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)

Subjects
Materials science, Absorption spectroscopy, Coprecipitation, Magnetic circular dichroism, Nanoparticle, 02 engineering and technology, Magnetic anisotropies, 010402 general chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 01 natural sciences, 0104 chemical sciences, Electronic, Optical and Magnetic Materials, Spinels, Condensed Matter::Materials Science, Physical chemistry, [CHIM]Chemical Sciences, Particle size, 0210 nano-technology, Anisotropy, Chemical composition, Stoichiometry
Abstract

International audience; Magnetic anisotropies and crystallographic structures of iron-cobalt nanospinels obtained with the co-precipitation synthesis process are revealed using X-ray Absorption Spectroscopy and X-ray Magnetic Circular Dichroism. The chemical process allows to obtain nanoparticles of various sizes and chemical composition, but it is the site symmetry environment of Co2+ that is found to be the crucial parameter that governs the magnetic anisotropies of the nanospinels. The distribution of Co2+ among the crystallographic sites of the structure is directly linked to the temperature of the synthesis process. In parallel, the results also revealed that a superficial rich shell of iron is formed for the iron-cobalt nanospinels stable in acidic medium leading to chemically inhomogeneous nanoparticles.

Published
2018

27. Magnetic (Hyper)Thermia or Photothermia? Progressive Comparison of Iron Oxide and Gold Nanoparticles Heating in Water, in Cells, and In Vivo

Author

Amanda K. A. Silva, Sophie Neveu, Ali Abou-Hassan, Claire Wilhelm, Riccardo Di Corato, Jelena Kolosnjaj-Tabi, Anouchka Plan Sangnier, Teresa Pellegrino, Luis M. Liz-Marzán, Alberto Curcio, and Ana Espinosa

Subjects
Materials science, Iron oxide, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 01 natural sciences, 0104 chemical sciences, Electronic, Optical and Magnetic Materials, Biomaterials, chemistry.chemical_compound, Chemical engineering, chemistry, In vivo, Colloidal gold, Electrochemistry, 0210 nano-technology
Abstract

Magnetic hyperthermia (MHT) and photothermal therapy (PTT) are emergent state‐of‐the‐art modalities for thermal treatment of cancer. While their mechanisms of action have distinct physical bases, both approaches rely on nanoparticle‐mediated remote onset of thermotherapy. Yet, are the two heating techniques interchangeable? Here, the heating obtained either with MHT or with PTT is compared. The heating is assessed in distinct environments and involves a set of nanomaterials differing in shape (spheres, cubes, stars, shells, and rods) as well as in composition (maghemite, magnetite, cobalt ferrite, and gold). The nanoparticle's heating efficacy in an aqueous medium is first evaluated. Subsequently, the heating efficiency within the cellular environment, where intracellular processing markedly decreases MHT, is compared. Conversely, endosomal sequestration could have a positive effect on PTT. Finally, iron oxide nanocubes and gold nanostars are compared in MHT and PTT in vivo within the heterogeneous intratumoral environment. Overall, two distinct therapeutic approaches, related to high dosage allowing MHT and low dosage associated with PTT, are identified. It is also demonstrated that PTT mediated by magnetic nanoparticles has an efficacy that is comparable to that of plasmonic nanoparticles, but only at significant nanoparticle dosages. At low concentrations, only plasmonic nanoparticles can deliver a therapeutic heating.

Published
2018

28. Can magneto-plasmonic nanohybrids efficiently combine photothermia with magnetic hyperthermia?

Author

Guillaume Radtke, Gianluigi A. Botton, Sophie Neveu, Ana Espinosa, Ali Abou-Hassan, Mathieu Bugnet, Claire Wilhelm, IMIM-Hospital del Mar, Generalitat de Catalunya, Matière et Systèmes Complexes (MSC (UMR_7057)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Department of Materials Science and Engineering, McMaster University, McMaster University [Hamilton, Ontario], Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Institut de recherche pour le développement [IRD] : UR206-Centre National de la Recherche Scientifique (CNRS)-Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Centre National de la Recherche Scientifique (CNRS)-ESPCI ParisTech-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de recherche pour le développement [IRD] : UR206-Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Matière et Systèmes Complexes (MSC), Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de recherche pour le développement [IRD] : UR206-Centre National de la Recherche Scientifique (CNRS), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Materials science, Nanoparticle, Nanotechnology, Hyperthermia, Induced, 02 engineering and technology, Photothermal therapy, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, 3. Good health, Nanomaterials, Cancer treatment, Magnetic Fields, Magnetic hyperthermia, Heat generation, Animals, Humans, General Materials Science, [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, Magnetite Nanoparticles, 0210 nano-technology, Magneto, Plasmon
Abstract

International audience; Multifunctional hybrid-design nanomaterials appear to be a promising route to meet the current therapeutics needs required for efficient cancer treatment. Herein, two efficient heat nano-generators were combined into a multifunctional single nanohybrid (a multi-core iron oxide nanoparticle optimized for magnetic hyperthermia, and a gold branched shell with tunable plasmonic properties in the NIR region, for photothermal therapy) which impressively enhanced heat generation, in suspension or in vivo in tumours, opening up exciting new therapeutic perspectives.s.

Published
2015

29. Magneto-optical Faraday effect in suspended core micro-structured optical fiber filled with magnetic CoFe2O4 nanoparticles doped composite material

Author

Frédéric Royer, Emmanuel Marin, Marie-Françoise Blanc-Mignon, Damien Jamon, Sophie Neveu, Laboratoire Hubert Curien [Saint Etienne] (LHC), Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS)-Institut d'Optique Graduate School (IOGS), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Institut d'Optique Graduate School (IOGS)-Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Hubert Curien (LHC), Institut d'Optique Graduate School (IOGS)-Université Jean Monnet - Saint-Étienne (UJM)-Centre National de la Recherche Scientifique (CNRS), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Optical fiber, Materials science, Optical isolator, Physics::Optics, 02 engineering and technology, 01 natural sciences, law.invention, symbols.namesake, law, 0103 physical sciences, Faraday effect, Fiber, Electrical and Electronic Engineering, Composite material, ComputingMilieux_MISCELLANEOUS, 010302 applied physics, Microstructured optical fiber, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, Core (optical fiber), Hardware and Architecture, symbols, [SPI.OPTI]Engineering Sciences [physics]/Optics / Photonic, Magnetic nanoparticles, 0210 nano-technology, Hard-clad silica optical fiber
Abstract

This paper deals with the study of the magneto-optical Faraday effect of micro-structured optical fibers with suspended cores covered by a silica matrix doped by CoFe2O4 nanoparticles. Two different size distributions of nanoparticles originated from two magnetic fluids have been used to dope a sol-gel preparation later introduced in the fiber. Faraday rotation measurements were performed in liquid state, thin film and finally in the fiber in guided configuration. The two different magnetic behaviors of these nanoparticles collections allow us to evidence the Faraday effect of the micro-structured optical fiber.

Published
2017

30. Biodegradation: Magneto-Thermal Metrics Can Mirror the Long-Term Intracellular Fate of Magneto-Plasmonic Nanohybrids and Reveal the Remarkable Shielding Effect of Gold (Adv. Funct. Mater. 9/2017)

Author

Gianluigi A. Botton, Sophie Neveu, Yoann Lalatonne, Guillaume Radtke, Ana Espinosa, François Mazuel, Ali Abou-Hassan, Matthieu Bugnet, and Claire Wilhelm

Subjects
Biomaterials, Materials science, Thermal, Electrochemistry, Shielding effect, Nanotechnology, Intracellular fate, Biodegradation, Condensed Matter Physics, Magneto, Plasmon, Electronic, Optical and Magnetic Materials
Published
2017

31. Magneto-Thermal Metrics Can Mirror the Long-Term Intracellular Fate of Magneto-Plasmonic Nanohybrids and Reveal the Remarkable Shielding Effect of Gold

Author

François Mazuel, Gianluigi A. Botton, Sophie Neveu, Ana Espinosa, Matthieu Bugnet, Guillaume Radtke, Claire Wilhelm, Ali Abou-Hassan, Yoann Lalatonne, Matière et Systèmes Complexes (MSC), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de recherche pour le développement [IRD] : UR206-Centre National de la Recherche Scientifique (CNRS), McMaster University [Hamilton, Ontario], PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Matière et Systèmes Complexes (MSC (UMR_7057)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de recherche pour le développement [IRD] : UR206-Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Université Paris Diderot - Paris 7 (UPD7)-Université Paris 13 (UP13)-Institut National de la Santé et de la Recherche Médicale (INSERM), and Abou-Hassan, Ali

Subjects
Materials science, Iron oxide, Nanotechnology, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Biomaterials, Magnetization, chemistry.chemical_compound, Thermal, Electrochemistry, Shielding effect, Dissolution, Plasmon, [CHIM.MATE] Chemical Sciences/Material chemistry, [CHIM.MATE]Chemical Sciences/Material chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, equipment and supplies, 0104 chemical sciences, Electronic, Optical and Magnetic Materials, Magnetic hyperthermia, chemistry, Magnetic core, 0210 nano-technology, human activities
Abstract

International audience; Multifunctional nanoparticles such as magneto‐plasmonic nanohybrids are rising theranostic agents. However, little is yet known of their fate within the cellular environment. In order to reach an understanding of their biotransformations, reliable metrics for tracking and quantification of such materials properties during their intracellular journey are needed. In this study, their long‐term (one month) intracellular fate is followed within stem‐cell spheroids used as tissue replicas. A set of magnetic (magnetization) and thermal (magnetic hyperthermia, photothermia) metrics is implemented to provide reliable insightsinto the intracellular status. It shows that biodegradation is modulated by the morphology and thickness of the gold shell. First a massive dissolution of the iron oxide core (nanoflower‐like) is observed, starting with dissociation of the multigrain structure. Second, it is demonstrated that an uninterrupted gold shell can preserve the magnetic core and properties (particularly magnetic hyperthermia). In addition to the magnetic and thermal metrics, intracellular high‐resolution chemical nanocartography evidences the gradual degradation of the magnetic cores. It also shows different transformation scenarios, from the release of small gold seeds when the magnetic core is dissolved (interesting for long‐term elimination) to the protection of the magnetic core (interesting for long‐term therapeutic applicability).

Published
2017

32. Preparation of Highly Anisotropic Cobalt Ferrite/Silica Microellipsoids Using an External Magnetic Field

Author

David Montero, Patricia Beaunier, Sébastien Abramson, Vincent Dupuis, Sophie Neveu, Physicochimie des Electrolytes, Colloïdes et Sciences Analytiques (PECSA), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Laboratoire de Réactivité de Surface (LRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Nanostructure, Materials science, Magnetic moment, Physics::Optics, Nanoparticle, 02 engineering and technology, Surfaces and Interfaces, 010402 general chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 01 natural sciences, 0104 chemical sciences, Magnetic field, Dipole, Magnetic anisotropy, Nuclear magnetic resonance, Chemical engineering, Electrochemistry, [CHIM]Chemical Sciences, Magnetic nanoparticles, General Materials Science, 0210 nano-technology, Anisotropy, Spectroscopy
Abstract

International audience; Magnetic cobalt ferrite/silica microparticles having both an original morphology and an anisotropic nanostructure are synthesized through the use of an external magnetic field and nanoparticles characterized by a high magnetic anisotropy. The association of these two factors implies that the ESE (emulsion and solvent evaporation) sol-gel method employed here allows the preparation of silica microellipsoids containing magnetic nanoparticles aggregated in large chains. It is clearly shown that without this combination, microspheres characterized by an isotropic distribution of the magnetic nanoparticles are obtained. While the chaining of the cobalt ferrite nanoparticles inside the silica matrix is related to the increase of their magnetic dipolar interactions, the ellipsoidal shape of the microparticles may be explained by the elongation of the sol droplets in the direction of the external magnetic field during the synthesis. Because of their highly anisotropic structure, these microparticles exhibit permanent magnetic moments, which are responsible, at a larger scale, for the existence of strong magnetic dipolar interactions. Therefore, when they are dispersed in water, the microellipsoids self-assemble into large and irregular chains. These interactions can be reinforced by the use of external magnetic field, allowing the preparation of very large permanent chains. This research illustrates how nanostructured particles exhibiting complex architectures can be elaborated through simple, fast, and low-cost methods, such as the use of external fields in combination with soft chemistry.

Published
2014

33. Physiological Remediation of Cobalt Ferrite Nanoparticles by Ferritin

Author

Jeanne Volatron, Jelena Kolosnjaj-Tabi, Yasir Javed, Quoc Lam Vuong, Yves Gossuin, Sophie Neveu, Nathalie Luciani, Miryana Hémadi, Florent Carn, Damien Alloyeau, and Florence Gazeau

Subjects
Article
Abstract

Metallic nanoparticles have been increasingly suggested as prospective therapeutic nanoplatforms, yet their long-term fate and cellular processing in the body is poorly understood. Here we examined the role of an endogenous iron storage protein – namely the ferritin – in the remediation of biodegradable cobalt ferrite magnetic nanoparticles. Structural and elemental analysis of ferritins close to exogenous nanoparticles within spleens and livers of mice injected in vivo with cobalt ferrite nanoparticles, suggests the intracellular transfer of degradation-derived cobalt and iron, entrapped within endogenous protein cages. In addition, the capacity of ferritin cages to accommodate and store the degradation products of cobalt ferrite nanoparticles was investigated in vitro in the acidic environment mimicking the physiological conditions that are present within the lysosomes. The magnetic, colloidal and structural follow-up of nanoparticles and proteins in the lysosome-like medium confirmed the efficient remediation of nanoparticle-released cobalt and iron ions by ferritins in solution. Metal transfer into ferritins could represent a quintessential process in which biomolecules and homeostasis regulate the local degradation of nanoparticles and recycle their by-products.

Published
2016

34. New approach for understanding experimental NMR relaxivity properties of magnetic nanoparticles: focus on cobalt ferrite

Author

Pierre Levitz, Patrice Porion, Sophie Neveu, Nadine Cherrak, Vincent Dupuis, Anne-Laure Rollet, PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Liquides Ioniques et Interfaces Chargées (LI2C), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Interfaces, Confinement, Matériaux et Nanostructures ( ICMN), Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de physique de la matière condensée (LPMC), and École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[PHYS]Physics [physics], Materials science, Magnetic moment, Relaxation (NMR), Analytical chemistry, General Physics and Astronomy, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, Quantitative Biology::Cell Behavior, Dipole, Condensed Matter::Materials Science, Cobalt ferrite, Physical chemistry, Magnetic nanoparticles, [CHIM]Chemical Sciences, Physical and Theoretical Chemistry, 0210 nano-technology
Abstract

International audience; Relaxivities r1 and r2 of cobalt ferrite magnetic nanoparticles (MNPs) have been investigated in the aim of improving the models of NMR relaxation induced by magnetic nanoparticles. On one hand a large set of relaxivity data has been collected for cobalt ferrite MNP dispersions. On the other hand the relaxivity has been calculated for dispersions of cobalt ferrite MNPs with size ranging from 5 to 13 nm, without using any fitting procedure. The model is based on the magnetic dipolar interaction between the magnetic moments of the MNPs and the 1H nuclei. It takes into account both the longitudinal and transversal contributions of the magnetic moments of MNPs leading to three contributions in the relaxation equations. The comparison of the experimental and theoretical data shows a good agreement of the NMR profiles as well as the temperature dependence.

Published
2016

35. Nanoscale distribution of magnetic anisotropies in bimagnetic soft core-hard shell MnFe$_2$O$_4$@CoFe$_2$O$_4$ nanoparticles

Author

Philippe Sainctavit, Niéli Daffé, Sophie Neveu, Marcin Sikora, Nadejda Bouldi, Véronica Gavrilov, Amélie Juhin, Dario Taverna, Fadi Choueikani, Vincent Dupuis, Mauro Rovezzi, Philippe Ohresser, Marie-Anne Arrio, Alexandre Gloter, Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Institut de recherche pour le développement [IRD] : UR206-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Sorbonne Université (SU), Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), AGH University of Science and Technology [Krakow, PL] (AGH UST), European Synchrotron Radiation Facility (ESRF), Dispositifs et Instrumentation en Optoélectronique et micro-ondes (DIOM), Université Jean Monnet [Saint-Étienne] (UJM), Laboratoire de Physique des Solides (LPS), and Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)

Subjects
Materials science, RIXS, XAS, Nanoparticle, FOS: Physical sciences, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Magnetization, RIXS‐MCD, [CHIM]Chemical Sciences, core–shell nanoparticles, Anisotropy, Saturation (magnetic), Nanoscopic scale, magnetic anisotropy, Condensed Matter - Materials Science, Condensed matter physics, XMCD, Mechanical Engineering, Inner core, Materials Science (cond-mat.mtrl-sci), [CHIM.MATE]Chemical Sciences/Material chemistry, Coercivity, spinel ferrites, 021001 nanoscience & nanotechnology, 3. Good health, 0104 chemical sciences, Magnetic anisotropy, Mechanics of Materials, 0210 nano-technology
Abstract

The nanoscale distribution of magnetic anisotropies was measured in core@shell MnFe$_2$O$_4$@CoFe$_2$O$_4$ 7.0 nm particles using a combination of element selective magnetic spectroscopies with different probing depths. As this picture is not accessible by any other technique, emergent magnetic properties were revealed. The coercive field is not constant in a whole nanospinel. The very thin (0.5 nm) CoFe$_2$O$_4$ hard shell imposes a strong magnetic anisotropy to the otherwise very soft MnFe$_2$O$_4$ core: a large gradient in coercivity was measured inside the MnFe$_2$O$_4$ core with lower values close to the interface region, while the inner core presents a substantial coercive field (0.54 T) and a very high remnant magnetization (90% of the magnetization at saturation)., Comment: 27 pages (including supporting information)

Published
2016
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36. Mercury-based cobalt magnetic fluids and cobalt nanoparticles

Author

Valérie Cabuil, Sophie Neveu, R. Massart, B. Rasolonjatovo, Liquides Ioniques et Interfaces Chargées (LI2C), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), and Cabuil, Valérie

Subjects
inorganic chemicals, MERCURE, Ferrofluid, Materials science, Inorganic chemistry, chemistry.chemical_element, Nanoparticle, One-Step, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Nuclear magnetic resonance, Pulmonary surfactant, ComputingMilieux_MISCELLANEOUS, [CHIM.MATE] Chemical Sciences/Material chemistry, [CHIM.MATE]Chemical Sciences/Material chemistry, equipment and supplies, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 0104 chemical sciences, Electronic, Optical and Magnetic Materials, Mercury (element), chemistry, Magnetic nanoparticles, 0210 nano-technology, human activities, Cobalt
Abstract

This paper describes the synthesis of a magnetic and conducting liquid consisting of cobalt nanoparticles dispersed in mercury. The magnetic nanoparticles are obtained in one step by the electroreduction of a cobalt(II) solution on mercury. These particles are then extracted using an organic solution of surfactant in order to obtain a ferrofluid based on cobalt nanoparticles.

Published
2007

37. Rheological investigations on the theoretical predicted 'Poisoning' effect in bidisperse ferrofluids

Author

Sophie Neveu, E. Siebert, Vincent Dupuis, Stefan Odenbach, PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Ferrofluid, Materials science, Economies of agglomeration, Rheometer, Thermodynamics, Context (language use), 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 01 natural sciences, 0104 chemical sciences, Electronic, Optical and Magnetic Materials, Magnetic field, Condensed Matter::Soft Condensed Matter, Physics::Fluid Dynamics, Nuclear magnetic resonance, Rheology, Particle-size distribution, [CHIM]Chemical Sciences, Small particles, 0210 nano-technology, ComputingMilieux_MISCELLANEOUS
Abstract

Interparticle interactions in ferrofluids especially the influence of small particles on the agglomeration behaviour of large particles were the topic of numerous theoretical predictions and simulations as well as of experimental investigations. In this context the “Poisoning” effect describes the decrease of the magnetoviscous effect in the presence of small particles in a bidisperse model fluid. In order to examine this effect rheological experiments have been carried out by means of a specially designed rheometer, which allows measurements under the influence of an applied magnetic field. We were able to synthesize ferrofluids with a narrow particle size distribution containing only small or large cobalt ferrite nanoparticles, which were mixed to receive various bidisperse fluid samples. With these fluids changes of the viscous behaviour in a magnetic field have been measured and compared according to their individual compositions.

Published
2015

38. Synthesis of Trimagnetic Multishell MnFe2O4@CoFe2O4@NiFe2O4 Nanoparticles

Author

Valérie Cabuil, Vincent Dupuis, Alexandre Gloter, Véronica Gavrilov-Isaac, Dario Taverna, Sophie Neveu, PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Institut de minéralogie et de physique des milieux condensés (IMPMC), Université Pierre et Marie Curie - Paris 6 (UPMC)-IPG PARIS-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), and Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Institut de Physique du Globe de Paris (IPG Paris)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Materials science, Nanoparticle, 02 engineering and technology, General Chemistry, Manganese ferrite, Coercivity, [CHIM.INOR]Chemical Sciences/Inorganic chemistry, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, Biomaterials, Soft core, Cobalt ferrite, Ferrite (magnet), Magnetic nanoparticles, [CHIM]Chemical Sciences, General Materials Science, Composite material, 0210 nano-technology, Nickel ferrite, ComputingMilieux_MISCELLANEOUS, Biotechnology
Abstract

The synthesis and characterization of original ferrite multishell magnetic nanoparticles made of a soft core (manganese ferrite) covered with two successive shells, a hard one (cobalt ferrite) and then a soft one (nickel ferrite), are described. The results demonstrate the modulation of the coercivity when new magnetic shells are added.

Published
2014

39. Self-biased cobalt ferrite nanocomposites for microwave applications

Author

Sophie Neveu, Faouzi Kahlouche, Ardaches Tchangoulian, Didier Vincent, A. Hannour, Vincent Dupuis, Laboratoire Telecom Claude Chappe (LT2C), Université Jean Monnet [Saint-Étienne] (UJM)-Ecole d'ingenieurs Telecom Saint Etienne, Laboratoire Hubert Curien [Saint Etienne] (LHC), Institut d'Optique Graduate School (IOGS)-Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS), Liquides Ioniques et Interfaces Chargées (LI2C), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Université Jean Monnet - Saint-Étienne (UJM)-Ecole d'ingénieurs Télécom Saint-Etienne (TSE), Laboratoire Hubert Curien (LHC), and Institut d'Optique Graduate School (IOGS)-Université Jean Monnet - Saint-Étienne (UJM)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Materials science, Nanocomposite, HFSS, Circulator, Nanoparticle, Condensed Matter Physics, 7. Clean energy, Ferromagnetic resonance, Electronic, Optical and Magnetic Materials, [SPI.TRON]Engineering Sciences [physics]/Electronics, Magnetic anisotropy, [SPI.ELEC]Engineering Sciences [physics]/Electromagnetism, Nuclear magnetic resonance, Remanence, Composite material, Microwave, ComputingMilieux_MISCELLANEOUS
Abstract

Oriented CoFe2O4 nanoparticles, dispersed in polymethyl methacrylate (PMMA) matrix, were fabricated by magnetophoretic deposition of functionalized nanocolloidal cobalt ferrite particles into porous alumina membrane. Their magnetic behavior exhibits an out-of-plane easy axis with a large remanent magnetization and coercitivity. This orientation allows high effective internal magnetic anisotropy that contributes to the permanent bias along the wire axis. The microwave studies reveal a ferromagnetic resonance at 46.5 and 49.5 GHz, depending on the filling ratio of the membrane. Ansoft High Frequency Structure Simulator (Ansoft HFSS) simulations are in good agreement with experimental results. Such nanocomposite is presented as one of the promising candidates for microwave devices (circulators, isolators, noise suppressors etc.).

Published
2014

40. Synthesis And Properties Of Magnetic Nanoparticles With Tunable Magnetic Anisotropy Energy

Author

Vincent Dupuis, Sophie Neveu, Véronica Gavrilov-Isaac, Sébastien Abramson, and Merwen Aouadi

Subjects
Magnetization, Magnetic anisotropy, Paramagnetism, Materials science, Anisotropy energy, Condensed matter physics, Nanoparticle, Magnetic nanoparticles, Coercivity, Magnetic susceptibility
Abstract

In this paper, we discuss several strategies to tailor magnetic properties related to the magnetic anisotropy energy, such as the blocking temperature or the low temperature coercivity, of magnetic nanoparticles or materials made with magnetic nanoparticles. We describe a first approach that consists in synthesizing and dispersing bi and tri-magnetic core-shell nanoparticles that include a core made of a material with a weak anisotropy energy density and a shell made with a material with a large anisotropy energy density. This approach is a promising route to tune the blocking temperature of low temperature coercivity of a particle without altering its magnetization and with a good control of its size. Additionally, we also explore another route for the control of the shape of the hysteresis loop of material made with magnetic nanoparticles that consists in the simple mixture of magnetically soft and hard magnetic nanoparticles to create binary mixtures. In this case, it is the mixing ratio that allows one to adjust the properties of the final material.

Published
2014

41. Alternating magneto-birefringence of ionic ferrofluids in crossed fields

Author

Sophie Neveu, E. Hasmonay, Emmanuelle Dubois, Jean-Claude Bacri, and Régine Perzynski

Subjects
Paramagnetism, Ferrofluid, Dipole, Materials science, Condensed matter physics, Field (physics), Magnetic energy, Magnetic nanoparticles, Condensed Matter Physics, Magnetostatics, Electronic, Optical and Magnetic Materials, Magnetic field
Abstract

A dynamic probing of magnetic liquids is performed experimentally, using a static magnetic field modulated by another smaller field, normal and alternating. The optical magneto-birefringence under these crossed magnetic fields is recorded as a function of the frequency for different field intensities and different sizes of the magnetic nanoparticles. A general reduced behavior is found for the in-phase and the out-of-phase optical response which is well-described by a simple mechanical model. Depending on the value Hani of the anisotropy field of the nanoparticles, we can distinguish two different high magnetic field regimes: - a rigid dipole regime (large anisotropy energy with respect to kBT) for cobalt ferrite nanoparticles with a relaxation time inversely proportional to the field intensity HC(HC Hani).

Published
2001

42. Surface waves in ferrofluids under vertical magnetic field

Author

Sophie Neveu, Julien Browaeys, Jean-Claude Bacri, C. Flament, Régine Perzynski, Laboratoire des Milieux Désordonnés et Hétérogènes (LMDH), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Liquides Ioniques et Interfaces Chargées (LI2C), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Physics, Ferrofluid, Condensed matter physics, Mechanics, Condensed Matter Physics, 01 natural sciences, 010305 fluids & plasmas, Electronic, Optical and Magnetic Materials, Magnetic field, Surface wave, Inviscid flow, Free surface, Dispersion relation, 0103 physical sciences, Shadowgraph, 010306 general physics, Critical field, ComputingMilieux_MISCELLANEOUS
Abstract

We present here new experimental results about the waves at the horizontal free surface of a magnetic fluid submitted to a normal magnetic field. The waves are generated by a small modulation at frequency of the vertical field . Using a shadowgraph method, we are able to measure the wavevector k of the 2D waves for a given value of and . The dispersion relation of the surface waves is established experimentally. On the other hand, we propose a theoretical derivation of the dispersion equation which includes a more complete treatment of the magnetic term than the previous works. Finally, we conclude that a linear and inviscid analysis is sufficient to fit well the experimental data, except in the vicinity of the critical field where a surface instability occurs.

Published
1999

43. Monodisperse magnetic nanoparticles: Preparation and dispersion in water and oils

Author

Emmanuelle Dubois, R. Massart, Sandrine Lefebure, Sophie Neveu, Valérie Cabuil, Liquides Ioniques et Interfaces Chargées (LI2C), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), and Neveu, Sophie

Subjects
Phase transition, Materials science, Dispersity, Maghemite, 02 engineering and technology, engineering.material, 010402 general chemistry, 01 natural sciences, law.invention, Magazine, law, General Materials Science, ComputingMilieux_MISCELLANEOUS, [CHIM.MATE] Chemical Sciences/Material chemistry, Range (particle radiation), Aqueous solution, Mechanical Engineering, [CHIM.MATE]Chemical Sciences/Material chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 0104 chemical sciences, Chemical engineering, Mechanics of Materials, engineering, Magnetic nanoparticles, 0210 nano-technology, Dispersion (chemistry)
Abstract

Nanometric maghemite and cobalt ferrite particles are chemically synthesized. The process produces particles polydisperse in size. The positive charges of their surface allow one to disperse them in aqueous acidic solutions and to obtain dispersions stabilized through electrostatic repulsions. Increasing acid concentration (in the range 0.1 to 0.5 mol.L−1), interparticles repulsions are screened and phase transitions are induced. Using this phenomenon, we describe a two-step size sorting process, in order to get significant amounts of nanometric monosized particles (with diameters monitored between typically 6 and 13 nm). As the surface of the latter is not modified by the size sorting process, usual procedures are used to disperse them in several aqueous or oily media.

Published
1998

44. Macro-Organized Patterns in Ferrofluid Layer: Experimental Studies

Author

C. Flament, Florence Elias, Jean-Claude Bacri, and Sophie Neveu

Subjects
Ferrofluid, Materials science, Condensed matter physics, Bubble, General Engineering, Statistical and Nonlinear Physics, Magnetic field, Physics::Fluid Dynamics, chemistry.chemical_compound, Nuclear magnetic resonance, chemistry, Ternary compound, Ferrite (magnet), Chevron (geology), Macro, Layer (electronics)
Abstract

We present some experimental results concerning the conformational instabilities observed in a thin layer made of an immiscible mixture of a magnetic fluid and another liquid submitted to an external magnetic field. We observed macroscopic domains with stripe or bubble shape. The transition bet~~een the two morphologies is observed and a coexistence of the two phases is visualized in a variable thickness layer. Furthermore, we give other results about the instabilities of the parallel stripe pattern: by increasing the external field the stripe pattern becomes a chevron structure, which also becomes unstable for higher values of the magnetic field and gives a hairpin pattern. Finally, we present a new system: a magnetic liquid froth in two dimensions which is analogous to soap froths with an additional external control parameter, the magnetic field.

Published
1997

45. Gyromagnetic resonance in ferrofluids made from manganese ferrite or magnetite particles: influence of a constant axial magnetic field

Author

L. Jorat, G. Noyel, Didier Vincent, and Sophie Neveu

Subjects
Ferrofluid, Materials science, Condensed matter physics, Field (physics), Resonance, Condensed Matter Physics, Electronic, Optical and Magnetic Materials, Magnetic field, chemistry.chemical_compound, Reflection (mathematics), chemistry, Anisotropy, Microwave, Magnetite
Abstract

We have measured the susceptibility of two ferrofluids in the frequency range 0.1–20 GHz. We confine the liquid under test in a coaxial line cell and we use the reflection/transmission method to obtain χ ∗ . If we add a constant axial magnetic field to the microwave field we evidence an increase of the gyromagnetic resonance phenomenon appearing as a consequence of the artificial increase of anisotropy.

Published
1996

46. Measurements of ferrofluid surface tension in confined geometry

Author

Sophie Neveu, S. Lacis, Andrejs Cebers, Jean-Claude Bacri, Régine Perzynski, and C. Flament

Subjects
Surface tension, Surface (mathematics), Ferrofluid, In plane, Materials science, Deformation (mechanics), Condensed matter physics, Geometry, Instability, Action (physics), Magnetic field
Abstract

Two methods of determination of the surface tension at the interface of a magnetic liquid and another fluid, in a confined two-dimensional geometry, are presented. The first is based upon a surface instability under the action of a vertical magnetic field and the second uses the deformation of a magnetic droplet in plane layer under the influence of a horizontal magnetic field. Theoretical calculations and experimental results are presented in both cases. Both determinations lead to comparable values of the surface tension $\ensuremath{\sigma}\ensuremath{\approx}3$ mN ${\mathrm{m}}^{\ensuremath{-}1}$.

Published
1996

47. Threshold and Marginal Curve of Magnetic Faraday Instability

Author

Sophie Neveu, Régine Perzynski, Andrejs Cebers, Jean-Claude Bacri, and J. C. Dabadie

Subjects
Physics, Surface (mathematics), Classical mechanics, Condensed matter physics, law, Excited state, General Physics and Astronomy, Limit (mathematics), Faraday cage, Instability, law.invention, Magnetic field
Abstract

A unidimensional Faraday instability is excited at the surface of a magnetic fluid with a horizontal and alternating magnetic field. The threshold and the marginal curve of the roll instability are theoretically derived and compared to experiment. Finite-size effects of the experimental vessel are investigated and interpreted. The predicted marginal curve is verified experimentally in the bulk limit conditions.

Published
1994

48. The magnetic fluid for heat transfer applications

Author

Sophie Neveu, Katsuto Nakatsuka, H. Koganezawa, B. Jeyadevan, Liquides Ioniques et Interfaces Chargées (LI2C), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Graduate school of engineering, and Department of Geoscience and technology-Tohoku University [Sendai]

Subjects
Materials science, heat pipe, Ionic bonding, Thermodynamics, 02 engineering and technology, 01 natural sciences, [SPI.MAT]Engineering Sciences [physics]/Materials, Nuclear magnetic resonance, Boiling, heat transfer, 0103 physical sciences, ionic magnetic fluid, ComputingMilieux_MISCELLANEOUS, 010302 applied physics, Critical heat flux, Thermomagnetic convection, equipment and supplies, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Electronic, Optical and Magnetic Materials, Magnetic field, Heat pipe, Heat transfer, real-time visual observation, 0210 nano-technology, human activities, Nucleate boiling
Abstract

Real-time visual observation of boiling water-based and ionic magnetic fluids (MFs) and heat transfer characteristics in heat pipe using ionic MF stabilized by citrate ions (JC-1) as working liquid are reported. Irrespective of the presence or absence of magnetic field water-based MF degraded during boiling. However, the degradation of JC-1 was avoided by heating the fluid in magnetic field. Furthermore, the heat transfer capacity of JC-1 heat pipe under applied magnetic field was enhanced over the no field case.

Published
2002

49. A Nanoscale Hybrid System Based on Gold Nanoparticles and Heteropolyanions

Author

Valérie Cabuil, Cédric R. Mayer, Sophie Neveu, Liquides Ioniques et Interfaces Chargées (LI2C), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Materials science, Colloidal gold, gold nanoparticles, Hybrid system, Nanotechnology, General Medicine, General Chemistry, heteropolyanions, [CHIM.INOR]Chemical Sciences/Inorganic chemistry, Nanoscopic scale, ComputingMilieux_MISCELLANEOUS, Catalysis
Abstract

International audience

Published
2002

50. Hybrid magneto-optical mode converter made with a magnetic nanoparticles-doped SiO2/ZrO2 layer coated on an ion-exchanged glass waveguide

Author

Sophie Neveu, Damien Jamon, Francois Royer, Hadi Amata, Jean Jacques Rousseau, François Parsy, Jean-Emmanuel Broquin, Fadi Choueikani, Dispositifs et Instrumentation en Optoélectronique et micro-ondes (DIOM), Université Jean Monnet - Saint-Étienne (UJM), Laboratoire Hubert Curien (LHC), Institut d'Optique Graduate School (IOGS)-Université Jean Monnet - Saint-Étienne (UJM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Charles Fabry de l'Institut d'Optique / Scop, Laboratoire Charles Fabry de l'Institut d'Optique (LCFIO), Université Paris-Sud - Paris 11 (UP11)-Institut d'Optique Graduate School (IOGS)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-Institut d'Optique Graduate School (IOGS)-Centre National de la Recherche Scientifique (CNRS), Institut de Microélectronique, Electromagnétisme et Photonique (IMEP), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National Polytechnique de Grenoble (INPG)-Centre National de la Recherche Scientifique (CNRS), Liquides Ioniques et Interfaces Chargées (LI2C), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Université Jean Monnet [Saint-Étienne] (UJM), Laboratoire Hubert Curien [Saint Etienne] (LHC), Institut d'Optique Graduate School (IOGS)-Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut d'Optique Graduate School (IOGS)-Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS)-Institut d'Optique Graduate School (IOGS)-Université Paris-Sud - Paris 11 (UP11), and Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique de Grenoble (INPG)-Université Joseph Fourier - Grenoble 1 (UJF)

Subjects
010302 applied physics, [PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics], Materials science, Physics and Astronomy (miscellaneous), Ion exchange, Annealing (metallurgy), business.industry, Doping, Physics::Optics, 02 engineering and technology, engineering.material, 021001 nanoscience & nanotechnology, 01 natural sciences, Waveguide (optics), Ion, Magnetic field, Optics, Coating, 0103 physical sciences, engineering, Magnetic nanoparticles, 0210 nano-technology, business
Abstract

International audience; This paper describes the possibility to achieve a TE-TM mode conversion in a magneto-optical hybrid waveguide operating at k¼1550 nm. This hybrid device is made by coating a SiO2/ZrO2 layer doped with magnetic nanoparticles on an ion-exchanged glass waveguide. Soft annealing (90 C) and UV treatment, both compatible with the ion exchange process, have been implemented to finalize the magneto-optical film. Optical characterizations that have been carried out demonstrated the efficiency of these hybrid structures in terms of lateral confinement and mode conversion. Indeed, TE to TM mode conversion has been observed when a longitudinal magnetic field is applied to the device. The amount of this conversion is discussed taking into account the distribution of light between the layer and the guide, and the modal birefringence of the structure.

Published
2011

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