The matching between multiple disciplines of urban rail transit is a key link to determine whether the design ability can be fully realized and the investment benefit can be brought into play. And the train speed is one of the crucial aspects and an important symbol for technical equipment, technical standards and operation management level of urban rail transits. For the problem of overlapping protection on speed control, this paper, by analyzing the influences of communication, signal, vehicle, track, environment and other restrictions on the train speed of fully automatic operation (FAO) lines, puts forward a speed matching control scheme under different operation modes such as ATO (automatic train operation) mode, ATP ( automatic train protection) mode, creep automatic mode and wash mode, discusses the method of determining the line structure design speed, vehicle construction speed, vehicle overspeed protection trigger speed, vehicle maximum dynamic envelope calculation speed, maximum ATP ceiling speed, and maximum ATO target speed according to the line grade speed, and defines the key speed recommendations of the matching design of multi disciplines. Meanwhile, by means of simulation and combined with the setting of different station spacing and the calculation of the minimum time speed curve, the design and selection principle of station spacing for lines with different speed grades ( i. e., 80, 100, and 120 km/ h) is investigated, and it is recommended that the distance between the three stations be no less than 1.0, 1.4 km and 2.5 km respectively. The optimization design of multi disciplines speed control and matching is helpful to maximize the performance of the system and equipment and ensure the overall operation level of the line. [ABSTRACT FROM AUTHOR]