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253 results on '"Mestres, G."'

4. Legume consumption is inversely associated with type 2 diabetes incidence in adults: A prospective assessment from the PREDIMED study

Author

Serra-Mir, M., Pérez-Heras, A., Viñas, C., Casas, R., Medina-Renom, A., Baena, J.M., García, M., Oller, M., Amat, J., Duaso, I., García, Y., Iglesias, C., Simón, C., Quinzavos, L., Parra, L., Liroz, M., Benavent, J., Clos, J., Pla, I., Amorós, M., Bonet, M.T., Martín, M.T., Sánchez, M.S., Altirriba, J., Manzano, E., Altés, A., Cofán, M., Valls-Pedret, C., Sala-Vila, A., Doménech, M., Bulló, M., Babio, N., Basora, J., González, R., Molina, C., Márquez, F., Martínez, P., Ibarrola, N., Sorlí, M., García Roselló, J., Castro, A., Martin, F., Tort, N., Isach, A., Guasch-Ferre, M., Cabré, J.J., Mestres, G., Paris, F., Llauradó, M., Pedret, R., Basells, J., Vizcaino, J., Segarra, R., Frigola, J., Costa-Vizcaino, J., Salas-Huetos, A., Boj, J., Montañes, D., Papandreou, Christopher, Fernández-Ballart, J., Carrasco, P., Ortega-Azorín, C., Asensio, E.M., Osma, R., Barragán, R., Francés, F., Guillén, M., González, J.I., Sáiz, C., Portolés, O., Giménez, F.J., Coltell, O., Fernández-Carrión, R., Guillem-Sáiz, P., González-Monje, I., Quiles, L., Pascual, V., Riera, C., Pages, M.A., Godoy, D., Carratalá-Calvo, A., Sánchez-Navarro, S., Valero-Barceló, C., Tello, S., Vila, J., de la Torre, R., Muñoz-Aguayo, D., Elosua, R., Marrugat, J., Schröder, H., Molina, N., Maestre, E., Rovira, A., Castañer, O., Farré, M., Toledo, E., Ruiz-Canela, M., Sanjulián, B., Sánchez-Tainta, A., Eguaras, S., Martí, A., Buil-Cosiales, P., SerranoMartínez, M., Diez-Espino, J., García-Arellano, A., Martínez-Lapiscina, E.H., Goñi, E., Vázquez, Z., Berrade, N., Extremera-Urabayen, V., Arroyo-Azpa, C., García-Pérez, L., Villanueva-Telleria, J., Cortés-Ugalde, F., Sagredo-Arce, T., Vigata-López, M.D., Arceiz Campo, M.T., Urtasun-Samper, A., Gueto Rubio, M.V., Churio-Beraza, B., Arós, F., Salaverria, I., del Hierro, T., Algorta, J., Francisco, S., Alonso-Gómez, A., Sanz, E., Rekondo, J., Belló, M.C., Loma-Osorio, A., Gómez-Gracia, E., Wärnberg, J., Benítez Pont, R., Bianchi Alba, M., Gómez-Huelgas, R., Martínez-González, J., Velasco García, V., de Diego Salas, J., Baca Osorio, A., Gil Zarzosa, J., Sánchez Luque, J.J., Vargas López, E., Ruiz-Gutiérrez, V., Sánchez Perona, J., Montero Romero, E., García-García, M., Jurado-Ruiz, E., Fiol, M., Romaguera, D., García-Valdueza, M., Moñino, M., Munuera, S., Vivó, M., Bestard, F., Munar, J.A., Coll, L., Proenza, A., Prieto, R., Frontera, G., Fiol, F., Ginard, M., Jover, A., García, J., Santos-Lozano, J.M., Ortega-Calvo, M., Mellado, L., García-Corte, F.J., Román, P., Iglesias, P., Corchado, Y., Miró-Moriano, L., Domínguez-Espinaco, C., Lozano-Rodriguez, J.M., Vaquero-Diaz, S., López- Sabater, M.C., Castellote-Bargalló, A.I., Quifer-Rada, P., Tresserra-Rimbau, A., Álvarez-Pérez, J., Díaz-Benítez, E.M., Sánchez-Villegas, A., Casañas-Quintana, L.T., Pérez-Cabrera, J., Ruano-Rodríguez, C., Bautista-Castaño, I., Sarmiento de la Fe, F., García Pastor, J.A., Díaz-González, B.V., Castillo Anzalas, J.M., Sosa-Also, R.E., Medina-Ponce, J., de la Cruz, E., Fanlo-Maresma, M., Galera, A., Trias, F., Sarasa, I., Corbella, E., Corbella, X., Cabezas, C., Vinyoles, E., Rovira, M.A., García, L., Flores, G., Verdú, J.M., Baby, P., Ramos, A., Mengual, L., Roura, P., Yuste, M.C., Guarner, A., Santamaría, M.I., Mata, M., de Juan, C., Brau, A., Tur, J.A., Portillo, M.P., Sáez, G., Aldamiz-Echevarría, M., Alonso-Gómez, A.M., Berjón, J., Forga, L., Gállego, J., García-Layana, A., Larrauri, A., Portu-Zapirain, J., Timiraus-Fernández, J., Becerra-Tomás, Nerea, Díaz-López, Andrés, Rosique-Esteban, Núria, Ros, Emilio, Buil-Cosiales, Pilar, Corella, Dolores, Estruch, Ramon, Fitó, Montserrat, Serra-Majem, Lluís, Arós, Fernando, Lamuela-Raventós, Rosa Maria, Fiol, Miquel, Santos-Lozano, José Manuel, Díez-Espino, Javier, Portoles, Olga, and Salas-Salvadó, Jordi

Published
2018
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11. Current role of the chimney technique in the treatment of complex abdominal aortic pathologies: A position paper from the PERICLES Registry investigators

Author

Donas, K. P., Criado, F., Torsello, G., Riambau, V., Scali, S., Minion, D., T. Lee J., Lachat, M., Y Woo, E., Veith, F. J., Fazzini, S., Taneva, Gt., Dalman, Rl, Tran, K, Pecoraro, F, Bisdas, T, Seifert, S, Esche, M, Gasparini, Frigatti, P, Adovasio, R, Mucelli, Fp, Damrauer, Sm, Salenius, J, Suominen, V, Mangialardi, N, Ronchey, S, Mestres, G, Mosquera, Nj., Donas K.P., Criado F., Torsello G., Riambau V., Scali S., Minion D., Lee J.T., Lachat M., Woo E.Y., Veith F.J., Fazzini S., Taneva G.T., Dalman R.L., Tran K., Pecoraro F., Bisdas T., Seifert S., Esche M., Gasparini D., Frigatti P., Adovasio R., Mucelli F.P., Damrauer S.M., Salenius J., Suominen V., Mangialardi N., Ronchey S., Mestres G., and Mosquera N.J.

Subjects
medicine.medical_specialty, Endoleak, Chimney technique, pararenal aneurysms, endovascular aortic repair, Risk Assessment, pararenal aneurysms, Blood Vessel Prosthesis Implantation, Risk Factors, Humans, Medicine, Radiology, Nuclear Medicine and imaging, Chimney, Registries, Chimney technique, endovascular aortic repair, Evidence-Based Medicine, business.industry, Endovascular Procedures, General Medicine, Blood Vessel Prosthesis, Treatment Outcome, Position paper, Stents, Surgery, Radiology, Current (fluid), Cardiology and Cardiovascular Medicine, business, Aortic Aneurysm, Abdominal
Abstract

Historically, chimney/snorkel endovascular aortic repair (Ch-EVAR) emerged as a rescue technique to revascularize and/or preserve inadvertently covered critical branch vessels during infrarenal aortic endografting. Next, in its evolutionary path, Ch-EVAR offered a viable treatment option for complex aortic repair, and particularly in situations where fenestrated/ branched EVAR was not a therapeutic option due to the lack of availability and/or anatomical constraints. In this context, this technique offered distinct advantages such as off-the-shelf availability, straightforward implantation techniques, and lower resource use-intensity enabling performance by a large number of operators managing patients in many centers around the world.

Published
2020

14. Diagnostic yield of 18F-FDG PET/CT in suspected diagnosis of vascular graft infection: A prospective cohort study

Author

Manuel Almela, Jaume Llopis, Ambrosioni J, Mestres G, A. Moreno, Riambau, Yugueros X, David Fuster, H. Bowles, Nuria Sánchez, Miró Jm, and Marta Hernández-Meneses

Subjects
medicine.medical_specialty, Blood vessel prosthesis, 030204 cardiovascular system & hematology, Infections, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, High morbidity, 0302 clinical medicine, Vascular graft infection, Positive predicative value, medicine, Suspected diagnosis, Radiology, Nuclear Medicine and imaging, Prospective cohort study, Severe complication, medicine.diagnostic_test, business.industry, Infeccions, Diagnòstic per la imatge, Estudi de casos, Pròtesis vasculars, Angiography, Diagnostic imaging, Fdg pet ct, Radiology, Case studies, Cardiology and Cardiovascular Medicine, business
Abstract

Background. Prosthetic vascular graft infection (PVGI) is a severe complication associated with high morbidity and mortality. Clinical diagnosis is complex, requiring image testing such as CT angiography or leukocyte scintigraphy, which has considerable limitations. The aim of this study was to know the diagnostic yield of PET/CT with 18F-Fluorodeoxyglucose (18F-FDG) in patients with suspected PVGI. Methods. We performed a prospective cohort study including 49 patients with suspected PVGI, median age of 62 ± 14 years. Three uptake patterns were defined following published recommendations: (i) focal, (ii) patched (PVGI criteria), and (iii) diffuse (no PVGI criterion). Results. Sensitivity, specificity, and positive and negative predictive values for 18F-FDG-PET/ CT were 88%, 79%, 67%, and 93%, respectively. 18F-FDG-PET/CT identified 14/16 cases of PVGI showing a focal (n = 10) or patched pattern (n = 4), being true negative in 26/33 cases with either a diffuse pattern (n = 16) or without uptake (n = 10). Five of the seven false-positive cases (71%) showed a patched pattern and all coincided with the application of adhesives for PVG placement. Conclusions. 18F-FDG-PET/CT is a useful technique for the diagnosis of PVGI. A patched pattern on PET/CT in patients in whom adhesives were applied for prosthetic vascular graft placement does not indicate infection. (J Nucl Cardiol 2018) Key Words: Fluorodeoxyglucose (FDG) Æ diagnostic and prognostic application Æ PET/CT imaging

Published
2020

16. European Society for Vascular Surgery (ESVS) Certification of Theoretical and Practical Competences in Basic Vascular Ultrasound: Validity Investigation of the Assessment Tools

Author

Nayahangan, L.J., primary, Vila, R., additional, Lawaetz, J., additional, Leal Lorenzo, J.I., additional, Bredahl, K.K., additional, Lawaetz, M., additional, Mestres, G., additional, Westerlin, L., additional, Rogers, S.K., additional, Fernandes, F., additional, Ortega, E.I., additional, Konge, L., additional, and Eiberg, J., additional

Published
2021
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19. Rationale and Study Design for an Individualized Perioperative Open Lung Ventilatory Strategy in Patients on One-Lung Ventilation (iPROVE-OLV)

Author

Carraminana, A, Ferrando, C, Unzueta, MC, Navarro, R, Suarez-Sipmann, F, Tusman, G, Garutti, I, Soro, M, Pozo, N, Librero, J, Gallego, L, Ramasco, F, Rabanal, JM, Rodriguez, A, Sastre, J, Martinez, J, Coves, S, Garcia, P, Aguirre-Puig, P, Yepes, J, Lluch, A, Lopez-Herrera, D, Leal, S, Vives, M, Bellas, S, Socorro, T, Trespalacios, R, Salazar, CJ, Mugarra, A, Cinnella, G, Spadaro, S, Futier, E, Ferrer, L, Cabrera, M, Ribeiro, H, Celestino, C, Kucur, E, Cervantes, O, Morocho, D, Delphy, D, Ramos, C, Villar, J, Belda, J, Monedero, P, Martinez, S, Comino, O, Coy, A, Armengol, L, Pineiro, P, Cruz, P, Duque, P, de la Gala, FA, Sanchez, G, Olmedilla, L, de la Fuente, E, Erquicia, I, Reyes, A, Lopez, E, Palencia, M, Bunger, B, Ramos, R, Terradillos, E, Almaraz, C, Lujan, LM, Lopez, A, Femenia, F, Botella, S, Cimadevilla, B, Pascual, R, Pardo, S, Gonzalez, M, Lopez, C, Trabanco, S, Zaldibar, E, Barolome, MJ, Pereira, D, Otero, T, Blanco, L, Reparaz, JR, Ceresuela, R, Castellano, P, Martinez, P, Martinez, O, Franco, J, Hernandez, J, Pastor, O, Solera, J, Guerra, E, Dib, ZH, Farina, R, Cabrera, S, Arribas, MP, Sastre, JA, de Celis, I, Pascual, MJ, Garcia-Barberena, B, Arango, E, Amaya, O, Madrid, G, Triana, C, Pabon, S, Diaz, DP, Ortells, F, Perez, B, Aracil, R, Sanchez, R, Acosta, J, de la Matta, M, Gonzalez, D, Mirabella, L, Rauseo, M, Lamanna, A, Volta, CA, Ragazzi, R, Cachapuz, M, Correia, I, Parera, A, Argilaga, M, Azparren, G, Bausili, M, Almajano, R, Aragon, C, Colas, A, Cotera, I, Embun, R, Forcada, P, Garces, C, Gil, F, Gracia, A, Herrero, M, Izquierdo, B, Molinos, I, Munoz, N, Puertolas, M, Quesada, N, Recuero, JL, Royo, I, Romero, B, Rubio, B, Sandin, F, Sanjuan-Villarreal, TA, Visiedo, S, Cordoba, J, Pintor, J, Planas, A, Nieves, JM, Garcia, E, Vallejo, C, Santidrian, S, Rofso, P, Arocas, B, Gutierrez, A, Charco, P, Parra, MJ, Carbonell, JA, Jurado, A, Serralta, F, Sancho, L, Barcena, E, Lascorz, L, Belmonte, L, Cuervo, J, Florea, R, Monleon, B, Perez, S, Garcia, L, Hurtado, L, Pardo, P, Segura, N, Utrera, E, Martin, B, Mellado, P, Arcas, JJ, Martinez, N, Maric, M, Munoz, LE, Gonzalez, RC, Busquets, J, Homs, M, Jimenez, A, Pintanel, T, Martinez, E, Moret, E, Sercakacilar, G, Diaz, M, Souteiro, JT, Benito, A, Cebrian, A, Mestres, G, Mohamed, MI, Yousef, SA, Osman, YM, Moreno, A, Tutillo, A, Pilco, H, Pena, A, Llano, M, Carrillo, E, Salazar, C, Dominguez, D, Espinosa, E, and iPROVE-OLV Network

Subjects
one-lung ventilation, postoperative pulmonary complications, respiratory system, mechanical ventilation, positive end-expiratory pressure, recruitment maneuvers
Abstract

Objective: The aim of this clinical trial is to examine whether it is possible to reduce postoperative complications using an individualized perioperative ventilatory strategy versus using a standard lung-protective ventilation strategy in patients scheduled for thoracic surgery requiring one-lung ventilation. Design: International, multicenter, prospective, randomized controlled clinical trial. Setting: A network of university hospitals. Participants: The study comprises 1,380 patients scheduled for thoracic surgery. Interventions: The individualized group will receive intraoperative recruitment maneuvers followed by individualized positive end-expiratory pressure (open lung approach) during the intraoperative period plus postoperative ventilatory support with high-flow nasal cannula, whereas the control group will be managed with conventional lung-protective ventilation. Measurements and Main Results: Individual and total number of postoperative complications, including atelectasis, pneumothorax, pleural effusion, pneumonia, acute lung injury; unplanned readmission and reintubation; length of stay and death in the critical care unit and in the hospital will be analyzed for both groups. The authors hypothesize that the intraoperative application of an open lung approach followed by an individual indication of high-flow nasal cannula in the postoperative period will reduce pulmonary complications and length of hospital stay in high-risk surgical patients. (C) 2019 Published by Elsevier Inc.

Published
2019

22. Dietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studies

Author

Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (España), Centro Nacional de Investigaciones Cardiovasculares (España), European Commission, Ministerio de Ciencia e Innovación (España), Fundación Mapfre, Junta de Andalucía, Generalitat de Catalunya, Generalitat Valenciana, Diputación Foral de Navarra, García-Arellano, Ana, Martínez-González, Miguel Ángel, Ramallal, Raúl, Salas-Salvadó, Jordi, Hébert, James R., Corella, Dolores, Shivappa, Nitin, Forga, Luis, Schröder, Helmut, Muñoz-Bravo, C., Estruch, Ramón, Hernández, P., Murillo, C., Mestres, G., Mengual, L., Serra-Majem, Lluis, Juan, C.de, Romaguera, Dora, Ruiz-Canela, Miguel, Vizcaíno, J., Bautista Castaño, I., Mendonça, Raquel Bicudo Deus, Farré, M., Basora-Gallisa, J., Barrio López, M.T., Buil-Cosiales, Pilar, Sarmiendo de la Fe, F., Medina-Remón, Alexander, Sánchez Luque, J. J., Sorlí, J., Cervantes, S., Pérez-Heras, A., Gil Zarzosa, J., Villanueva Moreno, R., Goni-Ochandorena, E., Lasanta-Sáez, M.J., Cia-Lecumberri, P., Fernandez-Urzainqui, L., Sáiz, C., Schroder, H., Carrasco, P., Doménech, M., Mellado, L., Toledo-Atucha, J., Guillen-Grima, F., Marrugat, J., Sáez, G., Ruiz Zambrana, A., Miró-Moriano, L., Zazpe Garcia, I, Godoy, D., Segarra, R., Toledo, Estefania, Molina, C., Loma-Osorio, A., Martínez, E., Bulló, Mònica, Vinyoles, E., Estremera-Urabayen, J. V., García, Y., Simón, C., Amorós, M., Navajas, R., Sánchez-Navarro, S., Casi, A., Pimenta, A. M., Tabar-Sarrias, J. A., Cruz, E. de la, Pascual-Pascual, P., Riera, C., García-Pérez, L., Carratalá-Calvo, A., Sanchez-Tainta, A., Ariz-Arnedo, M.J., Galera, A., Arina-Vergara, E., Martínez-González, José, Munuera, S., Francés, F., Felipe, I., Martínez, P., Gea, A., Díaz-López, A., Santana Santana, A. J., Serra-Mir, Mercè, Ros, Emilio, Villanueva, P., Becerra-Tomás, Nerea, Rosique-Esteban, N., Papandreou, Christopher, García, J., Prieto, R., Bestard, F., Osma, R., Baena, J.M., Figuerido-Garmendia, E., Pla, I., Tafalla, M., Benavent, J., Sánchez, M. S., Proenza, A., García, M., Vivo, M., Garcés Ducar, M. L., Bonet, M.T., Casas, Ricard, Bobe, I., Altés, A., Ginard, M., Díez-Espino, Javier, López-Sabater, M. C., Wärnberg, Julia, Valls-Pedret, C., Basells, J., Serrano-Martinez, M., Giménez, F.J., Velasco García, V., González, R., González, J. I., Barragán, Rocío, Martín, F., Muñoz-Aguayo, Daniel, Elosua, Roberto, Rovira, A., Fernández-Rodríguez, M. J., Román, Pablo, Quifer-Rada, P., Fernández-Crehuet, Joaquín, Llorca, J., Tort, N., Iglesias, P., Clos, J., Ferreira, C., Lopez del Burgo, C., Llauradó, M., Sarasa, Iziar, Jover, A., Altirriba, J., Bianchi Alba, M., Lahortiga, F., García-Rodriguez, A., Cabeza-Beunza, J. A., Fernández-Ballart, J., Pascual, V., Pages, M.A., del Hierro, T., Mata, M., Corbella, X., García, L., Maestre, E., Barcena, A. F., Sorlí, José V., Carlos, Silvia, Balanza, R., Rodríguez, M. A., Pedret, R., Castañer, Olga, Oreja-Arrayago, C., Ortega-Azorín, Carolina, Cervello, T., Maldonado Díaz, I., Ramos, A., Gómez-Huelgas, R., García Roselló, J., Benito Crochon, S., Arroyo-Azpa, C., Guillén, M., Martín, M. T., Coltell, O., García-Valdueza, M., Frontera, G., Fernandez Montero, A., Rosa, Pedro Antonio de la, Tur, Josep A., Díez Benítez, E., Razquin, Cristina, Molina, N., Salaverria Lete, Itziar, Amat, J., Alonso, A., Araque, M., Fernández-Carrión, Rebeca, Montull, I., Asensio, Eva M., Algorta, J., Portolés, Olga, Duaso, I., Sanz, E., Donat-Vargas, Carolina, Sayón-Orea, Carmen, Guarner, A., Fiol, F., Guasch‐Ferré, Marta, Simón García, C., Oller, M., Brau, A., Benítez Pont, R., Sánchez-Villegas, A., Diego Salas, J. de, Domínguez-Espinaco, C., Vaquero-Díaz, S., Lozano-Rodríguez, J.M., Marti, A., Núñez-Córdoba, J.M., Vázquez Ruiz, Z., Roura, P., Babio, Nancy, Baca Osorio, A., Valero-Barcelo, C., Basterra-Gortari, F. Javier, Salas-Huetos, A., Munar, J.A., Elcarte-Lopez, T., Donazar, M., San Vicente, J., Santamaria, M. I., Isach, A., Yuste, M. C., Ortega-Calvo, Manuel, Pintó-Salas, X., Trias, Ferrán, Muñoz, Miguel Ángel, Viñas, C., Esparza-López, J.M., Martínez-Mazo, M.D., Bes-Rastrollo, M., Vila, J., Castellote-Bargalló, Ana I., Leal, M., Artal-Moneva, F., Coll, L., Lamuela-Raventós, Rosa M., Torre, Rafael de la, Tresserra-Rimbau, A., Quinzavos, L., Sanjulian, B., Macua-Martínez, T., Irala, J. de, Sala-Vila, Aleix, Tello, S., Beunza, J.J., Francisco, S., Falcón Sanabria, I., Díaz, A., Solis, E., Lapetra, José, Mena, G., Liroz, M., Manzano, E., Corchado, Y., Goday, A., Gonzaláz-Monje, I., Rovira, M.A., Iglesias, C., Macías Gutiérrez, B., Parra, L., Álvarez-Pérez, J., Cabezas, C., Quiles, L., Baby, P., Ibarrola-Jurado, Nuria, Cabre, M., Parra-Osés, A., Cofán, Montserrat, Fuente, Carmen de la, Santos-Lozano, J. M., Guillem-Saiz, P., Martínez, J. A., Fernández, M., Mari-Sanchıs, A., Rico, A., Giardina, S., Canudas, Silvia, Paris, F., Marti Massó, R., Gutierrez, E., Corbella, Emili, Fiol, Miquel, Vargas López, E., Portillo, María P., Rekondo, Javier, Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (España), Centro Nacional de Investigaciones Cardiovasculares (España), European Commission, Ministerio de Ciencia e Innovación (España), Fundación Mapfre, Junta de Andalucía, Generalitat de Catalunya, Generalitat Valenciana, Diputación Foral de Navarra, García-Arellano, Ana, Martínez-González, Miguel Ángel, Ramallal, Raúl, Salas-Salvadó, Jordi, Hébert, James R., Corella, Dolores, Shivappa, Nitin, Forga, Luis, Schröder, Helmut, Muñoz-Bravo, C., Estruch, Ramón, Hernández, P., Murillo, C., Mestres, G., Mengual, L., Serra-Majem, Lluis, Juan, C.de, Romaguera, Dora, Ruiz-Canela, Miguel, Vizcaíno, J., Bautista Castaño, I., Mendonça, Raquel Bicudo Deus, Farré, M., Basora-Gallisa, J., Barrio López, M.T., Buil-Cosiales, Pilar, Sarmiendo de la Fe, F., Medina-Remón, Alexander, Sánchez Luque, J. J., Sorlí, J., Cervantes, S., Pérez-Heras, A., Gil Zarzosa, J., Villanueva Moreno, R., Goni-Ochandorena, E., Lasanta-Sáez, M.J., Cia-Lecumberri, P., Fernandez-Urzainqui, L., Sáiz, C., Schroder, H., Carrasco, P., Doménech, M., Mellado, L., Toledo-Atucha, J., Guillen-Grima, F., Marrugat, J., Sáez, G., Ruiz Zambrana, A., Miró-Moriano, L., Zazpe Garcia, I, Godoy, D., Segarra, R., Toledo, Estefania, Molina, C., Loma-Osorio, A., Martínez, E., Bulló, Mònica, Vinyoles, E., Estremera-Urabayen, J. V., García, Y., Simón, C., Amorós, M., Navajas, R., Sánchez-Navarro, S., Casi, A., Pimenta, A. M., Tabar-Sarrias, J. A., Cruz, E. de la, Pascual-Pascual, P., Riera, C., García-Pérez, L., Carratalá-Calvo, A., Sanchez-Tainta, A., Ariz-Arnedo, M.J., Galera, A., Arina-Vergara, E., Martínez-González, José, Munuera, S., Francés, F., Felipe, I., Martínez, P., Gea, A., Díaz-López, A., Santana Santana, A. J., Serra-Mir, Mercè, Ros, Emilio, Villanueva, P., Becerra-Tomás, Nerea, Rosique-Esteban, N., Papandreou, Christopher, García, J., Prieto, R., Bestard, F., Osma, R., Baena, J.M., Figuerido-Garmendia, E., Pla, I., Tafalla, M., Benavent, J., Sánchez, M. S., Proenza, A., García, M., Vivo, M., Garcés Ducar, M. L., Bonet, M.T., Casas, Ricard, Bobe, I., Altés, A., Ginard, M., Díez-Espino, Javier, López-Sabater, M. C., Wärnberg, Julia, Valls-Pedret, C., Basells, J., Serrano-Martinez, M., Giménez, F.J., Velasco García, V., González, R., González, J. I., Barragán, Rocío, Martín, F., Muñoz-Aguayo, Daniel, Elosua, Roberto, Rovira, A., Fernández-Rodríguez, M. J., Román, Pablo, Quifer-Rada, P., Fernández-Crehuet, Joaquín, Llorca, J., Tort, N., Iglesias, P., Clos, J., Ferreira, C., Lopez del Burgo, C., Llauradó, M., Sarasa, Iziar, Jover, A., Altirriba, J., Bianchi Alba, M., Lahortiga, F., García-Rodriguez, A., Cabeza-Beunza, J. A., Fernández-Ballart, J., Pascual, V., Pages, M.A., del Hierro, T., Mata, M., Corbella, X., García, L., Maestre, E., Barcena, A. F., Sorlí, José V., Carlos, Silvia, Balanza, R., Rodríguez, M. A., Pedret, R., Castañer, Olga, Oreja-Arrayago, C., Ortega-Azorín, Carolina, Cervello, T., Maldonado Díaz, I., Ramos, A., Gómez-Huelgas, R., García Roselló, J., Benito Crochon, S., Arroyo-Azpa, C., Guillén, M., Martín, M. T., Coltell, O., García-Valdueza, M., Frontera, G., Fernandez Montero, A., Rosa, Pedro Antonio de la, Tur, Josep A., Díez Benítez, E., Razquin, Cristina, Molina, N., Salaverria Lete, Itziar, Amat, J., Alonso, A., Araque, M., Fernández-Carrión, Rebeca, Montull, I., Asensio, Eva M., Algorta, J., Portolés, Olga, Duaso, I., Sanz, E., Donat-Vargas, Carolina, Sayón-Orea, Carmen, Guarner, A., Fiol, F., Guasch‐Ferré, Marta, Simón García, C., Oller, M., Brau, A., Benítez Pont, R., Sánchez-Villegas, A., Diego Salas, J. de, Domínguez-Espinaco, C., Vaquero-Díaz, S., Lozano-Rodríguez, J.M., Marti, A., Núñez-Córdoba, J.M., Vázquez Ruiz, Z., Roura, P., Babio, Nancy, Baca Osorio, A., Valero-Barcelo, C., Basterra-Gortari, F. Javier, Salas-Huetos, A., Munar, J.A., Elcarte-Lopez, T., Donazar, M., San Vicente, J., Santamaria, M. I., Isach, A., Yuste, M. C., Ortega-Calvo, Manuel, Pintó-Salas, X., Trias, Ferrán, Muñoz, Miguel Ángel, Viñas, C., Esparza-López, J.M., Martínez-Mazo, M.D., Bes-Rastrollo, M., Vila, J., Castellote-Bargalló, Ana I., Leal, M., Artal-Moneva, F., Coll, L., Lamuela-Raventós, Rosa M., Torre, Rafael de la, Tresserra-Rimbau, A., Quinzavos, L., Sanjulian, B., Macua-Martínez, T., Irala, J. de, Sala-Vila, Aleix, Tello, S., Beunza, J.J., Francisco, S., Falcón Sanabria, I., Díaz, A., Solis, E., Lapetra, José, Mena, G., Liroz, M., Manzano, E., Corchado, Y., Goday, A., Gonzaláz-Monje, I., Rovira, M.A., Iglesias, C., Macías Gutiérrez, B., Parra, L., Álvarez-Pérez, J., Cabezas, C., Quiles, L., Baby, P., Ibarrola-Jurado, Nuria, Cabre, M., Parra-Osés, A., Cofán, Montserrat, Fuente, Carmen de la, Santos-Lozano, J. M., Guillem-Saiz, P., Martínez, J. A., Fernández, M., Mari-Sanchıs, A., Rico, A., Giardina, S., Canudas, Silvia, Paris, F., Marti Massó, R., Gutierrez, E., Corbella, Emili, Fiol, Miquel, Vargas López, E., Portillo, María P., and Rekondo, Javier

Abstract

[Background]: Inflammation is known to be related to the leading causes of death including cardiovascular disease, several types of cancer, obesity, type 2 diabetes, depression-suicide and other chronic diseases. In the context of whole dietary patterns, the Dietary Inflammatory Index (DII®) was developed to appraise the inflammatory potential of the diet. [Objective]: We prospectively assessed the association between DII scores and all-cause mortality in two large Spanish cohorts and valuated the consistency of findings across these two cohorts and results published based on other cohorts., [Design]: We assessed 18,566 participants in the “Seguimiento Universidad de Navarra” (SUN) cohort followed-up during 188,891 person-years and 6790 participants in the “PREvencion con DIeta MEDiterránea” (PREDIMED) randomized trial representing 30,233 person-years of follow-up. DII scores were calculated in both cohorts from validated FFQs. Higher DII scores corresponded to more proinflammatory diets. A total of 230 and 302 deaths occurred in SUN and PREDIMED, respectively. In a random-effect meta-analysis we included 12 prospective studies (SUN, PREDIMED and 10 additional studies) that assessed the association between DII scores and all-cause mortality., [Results]: After adjusting for a wide array of potential confounders, the comparison between extreme quartiles of the DII showed a positive and significant association with all-cause mortality in both the SUN (hazard ratio [HR] = 1.85; 95% CI: 1.15, 2.98; P-trend = 0.004) and the PREDIMED cohort (HR = 1.42; 95% CI: 1.00, 2.02; P-trend = 0.009). In the meta-analysis of 12 cohorts, the DII was significantly associated with an increase of 23% in all-cause mortality (95% CI: 16%–32%, for the highest vs lowest category of DII)., [Conclusion]: Our results provide strong and consistent support for the hypothesis that a pro-inflammatory diet is associated with increased all-cause mortality. The SUN cohort and PREDIMED trial were registered at clinicaltrials.gov as NCT02669602 and at isrctn.com as ISRCTN35739639, respectively.

Published
2019

25. Dietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studies

Author

Garcia-Arellano, Ana, primary, Martínez-González, Miguel A., additional, Ramallal, Raul, additional, Salas-Salvadó, Jordi, additional, Hébert, James R., additional, Corella, Dolores, additional, Shivappa, Nitin, additional, Forga, Luis, additional, Schröder, Helmut, additional, Muñoz-Bravo, Carlos, additional, Estruch, Ramón, additional, Fiol, Miquel, additional, Lapetra, José, additional, Serra-Majem, Lluís, additional, Ros, Emilio, additional, Rekondo, Javier, additional, Toledo, Estefanía, additional, Razquin, Cristina, additional, Ruiz-Canela, Miguel, additional, Alonso, A., additional, Barrio Lopez, M.T., additional, Basterra-Gortari, F.J., additional, Benito Corchon, S., additional, Bes-Rastrollo, M., additional, Beunza, J.J., additional, Carlos, S., additional, Cervantes, S., additional, de Irala, J., additional, de la Rosa, P.A., additional, de la Fuente, C., additional, Donat-Vargas, C.L., additional, Donazar, M., additional, Fernandez Montero, A., additional, Gea, A., additional, Goni-Ochandorena, E., additional, Guillen-Grima, F., additional, Lahortiga, F., additional, Llorca, J., additional, Lopez del Burgo, C., additional, Mari-Sanchıs, A., additional, Marti, A., additional, Mendonça, R., additional, Nuñez-Cordoba, J.M., additional, Pimenta, A.M., additional, Rico, A., additional, Ruiz Zambrana, A., additional, Sayon-Orea, C., additional, Toledo-Atucha, J., additional, Vazquez Ruiz, Z., additional, Zazpe Garcıa, I., additional, Sánchez- Tainta, A., additional, Buil-Cosiales, P., additional, Díez-Espino, J., additional, Sanjulian, B., additional, Martínez, J.A., additional, Serrano-Martínez, M., additional, Extremera-Urabayen, J.V., additional, Garcia-Pérez, L., additional, Arroyo-Azpa, C., additional, Barcena, A.F., additional, Oreja-Arrayago, C., additional, Lasanta-Sáez, M.J., additional, Cia-Lecumberri, P., additional, Elcarte-Lopez, T., additional, Artal-Moneva, F., additional, Esparza-López, J.M., additional, Figuerido-Garmendia, E., additional, Tabar-Sarrias, J.A., additional, Fernández- Urzainqui, L., additional, Ariz-Arnedo, M.J., additional, Cabeza-Beunza, J.A., additional, Pascual-Pascual, P., additional, Martínez-Mazo, M.D., additional, Arina-Vergara, E., additional, Macua-Martínez, T., additional, Pascual Pascual, P., additional, Garcés Ducar, M.L., additional, Martí Massó, R., additional, Villanueva Moreno, R., additional, Parra-Osés, A., additional, Serra-Mir, M., additional, Pérez-Heras, A., additional, Viñas, C., additional, Casas, R., additional, Medina-Remon, A., additional, Villanueva, P., additional, Baena, J.M., additional, García, M., additional, Oller, M., additional, Amat, J., additional, Duaso, I., additional, García, Y., additional, Iglesias, C., additional, Simón, C., additional, Quinzavos, L., additional, Parra, L., additional, Liroz, M., additional, Benavent, J., additional, Clos, J., additional, Pla, I., additional, Amorós, M., additional, Bonet, M.T., additional, Martín, M.T., additional, Sánchez, M.S., additional, Altirriba, J., additional, Manzano, E., additional, Altés, A., additional, Cofán, M., additional, Valls-Pedret, C., additional, Sala-Vila, A., additional, Doménech, M., additional, Bulló, M., additional, Basora-Gallisa, J., additional, González, R., additional, Molina, C., additional, Mena, G., additional, Martínez, P., additional, Ibarrola, N., additional, Sorlí, J., additional, García Roselló, J., additional, Martin, F., additional, Tort, N., additional, Isach, A., additional, Babio, N., additional, Salas-Huetos, A., additional, Becerra-Tomás, N., additional, Rosique- Esteban, N., additional, Hernandez, P., additional, Canudas, S., additional, Papandreou, C., additional, Ferreira, C., additional, Cabre, M., additional, Mestres, G., additional, Paris, F., additional, Llauradó, M., additional, Pedret, R., additional, Basells, J., additional, Vizcaino, J., additional, Segarra, R., additional, Giardina, S., additional, Guasch-Ferré, M., additional, Díaz-López, A., additional, Fernández-Ballart, J., additional, Balanza, R., additional, Tello, S., additional, Vila, J., additional, de la Torre, R., additional, Muñoz-Aguayo, D., additional, Elosua, R., additional, Marrugat, J., additional, Schröder, H., additional, Molina, N., additional, Maestre, E., additional, Rovira, A., additional, Castañer, O., additional, Farré, M., additional, Sorli, J., additional, Carrasco, P., additional, Ortega-Azorín, C., additional, Asensio, E.M., additional, Osma, R., additional, Barragán, R., additional, Francés, F., additional, Guillén, M., additional, González, J.I., additional, Sáiz, C., additional, Portolés, O., additional, Giménez, F.J., additional, Coltell, O., additional, Fernández-Carrión, R., additional, Guillem-Sáiz, P., additional, González-Monje, I., additional, Quiles, L., additional, Pascual, V., additional, Riera, C., additional, Pages, M.A., additional, Godoy, D., additional, Carratalá-Calvo, A., additional, Sánchez-Navarro, S., additional, Valero-Barceló, C., additional, Salaverria, I., additional, Hierro, T. del, additional, Algorta, J., additional, Francisco, S., additional, San Vicente, J., additional, Casi, A., additional, Sanz, E., additional, Felipe, I., additional, Rekondo, J., additional, Loma-Osorio, A., additional, Fernandez-Crehuet, J., additional, Garcia-Rodriguez, A., additional, Wärnberg, J., additional, Benitez Pont, R., additional, Bianchi Alba, M., additional, Navajas, R., additional, Gómez-Huelgas, R., additional, Martínez-González, J., additional, Velasco García, V., additional, de Diego Salas, J., additional, Baca Osorio, A., additional, Gil Zarzosa, J., additional, Sánchez Luque, J.J., additional, Vargas López, E., additional, Romaguera, D., additional, García-Valdueza, M., additional, Proenza, A., additional, Prieto, R., additional, Frontera, G., additional, Munuera, S., additional, Vivó, M., additional, Bestard, F., additional, Munar, J.A., additional, Coll, L., additional, Fiol, F., additional, Ginard, M., additional, Jover, A., additional, García, J., additional, Santos-Lozano, J.M., additional, Ortega-Calvo, M., additional, Leal, M., additional, Martínez, E., additional, Mellado, L., additional, Miró-Moriano, L., additional, Domínguez-Espinaco, C., additional, Vaquero- Diaz, S., additional, Iglesias, P., additional, Román, P., additional, Corchado, Y., additional, Lozano-Rodríguez, J.M., additional, Lamuela-Raventós, R., additional, López- Sabater, M.C., additional, Castellote-Bargalló, A.I., additional, Quifer-Rada, P., additional, Tresserra-Rimbau, A., additional, Alvarez-Pérez, J., additional, Díez Benítez, E., additional, Bautista Castaño, I., additional, Maldonado Díaz, I., additional, Sanchez-Villegas, A., additional, Férnandez- Rodríguez, M.J., additional, Sarmiendo de la Fe, F., additional, Simón García, C., additional, Falcón Sanabria, I., additional, Macías Gutiérrez, B., additional, Santana Santana, A.J., additional, de la Cruz, E., additional, Galera, A., additional, Pintó-Salas, X., additional, Trias, F., additional, Sarasa, I., additional, Rodríguez, M.A., additional, Corbella, X., additional, Corbella, E., additional, Goday, A., additional, Muñoz, M.A., additional, Cabezas, C., additional, Vinyoles, E., additional, Rovira, M.A., additional, Garcia, L., additional, Baby, P., additional, Ramos, A., additional, Mengual, L., additional, Roura, P., additional, Yuste, M.C., additional, Guarner, A., additional, Santamaria, M.I., additional, Mata, M., additional, de Juan, C., additional, Brau, A., additional, Fernandez, M., additional, Gutierrez, E., additional, Murillo, C., additional, Garcia, J., additional, Tafalla, M., additional, Bobe, I., additional, Díaz, A., additional, Araque, M., additional, Solis, E., additional, Cervello, T., additional, Montull, I., additional, Tur, J.A., additional, Portillo, M.P., additional, and Sáez, G., additional

Published
2019
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27. Collected World Experience About the Performance of the Snorkel/Chimney Endovascular Technique in the Treatment of Complex Aortic Pathologies

Author

Donas, K. P., Lee, J. T., Lachat, M., Torsello, G., Veith, F. J., Dalman, R. L., Tran, K., Pecoraro, F., Bisdas, T., Seifert, S., Esche, M., Gasparini, D., Frigatti, P., Adovasio, R., Mucelli, F. P., Damrauer, S. M., Woo, E. Y., Beck, A., Scali, S., Minion, D., Salenius, J., Suominen, V., Mangialardi, N., Ronchey, S., Fazzini, S., Mestres, G., Riambau, V., Mosquera, N. J., Donas, K., Lee, J., Lachat, M., Torsello, G., Veith, F., Dalman, R., Tran, K., and Pecoraro, F.

Subjects
Registrie, Male, medicine.medical_treatment, Kaplan-Meier Estimate, Global Health, Settore MED/22 - Chirurgia Vascolare, Severity of Illness Index, Endovascular aneurysm repair, Aortic aneurysm, Retrospective Studie, Stent, Registries, Abdominal aortic aneurysm, Endovascular, Fenestrated, Thoracoabdominal, Vascular, Aortic Aneurysm, Abdominal, Aortography, Blood Vessel Prosthesis Implantation, Endovascular Procedures, Europe, Female, Follow-Up Studies, Humans, Prosthesis Design, Prosthesis Failure, Retrospective Studies, Risk Assessment, Stents, Survival Rate, Treatment Outcome, United States, Blood Vessel Prosthesis, medicine.diagnostic_test, Medicine (all), Aortic Aneurysm, Blood Vessel Prosthesi, Human, United State, medicine.medical_specialty, Follow-Up Studie, Blood vessel prosthesis, medicine, Abdominal, Survival rate, Endovascular Procedure, business.industry, Retrospective cohort study, medicine.disease, Surgery, business, Abdominal surgery
Abstract

OBJECTIVES: We sought to analyze the collected worldwide experience with use of snorkel/chimney endovascular aneurysm repair (EVAR) for complex abdominal aneurysm treatment. BACKGROUND: EVAR has largely replaced open surgery worldwide for anatomically suitable aortic aneurysms. Lack of availability of fenestrated and branched devices has encouraged an alternative strategy utilizing parallel or snorkel/chimney grafts (ch-EVAR). METHODS: Clinical and radiographic information was retrospectively reviewed and analyzed on 517 patients treated by ch-EVAR from 2008 from 2014 by prearranged defined and documented protocols. RESULTS: A total of 119 patients in US centers and 398 in European centers were treated during the study period. US centers preferentially used Zenith stent-grafts (54.2%) and European centers Endurant stent-grafts (62.2%) for the main body component. Overall 898 chimney grafts (49.2% balloon expandable, 39.6% self-expanding covered stents, and 11.2% balloon expandable bare metal stents) were placed in 692 renal arteries, 156 superior mesenteric arteries (SMA), and 50 celiac arteries. At a mean follow-up of 17.1 months (range: 1-70 months), primary patency was 94%, with secondary patency of 95.3%. Overall survival of patients in this high-risk cohort for open repair at latest follow-up was 79%. CONCLUSIONS: This global experience represents the largest series in the ch-EVAR literature and demonstrates comparable outcomes to those in published reports of branched/fenestrated devices, suggesting the appropriateness of broader applicability and the need for continued careful surveillance. These results support ch-EVAR as a valid off-the-shelf and immediately available alternative in the treatment of complex abdominal EVAR and provide impetus for the standardization of these techniques in the future.

Published
2015
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28. Legume consumption is inversely associated with type 2 diabetes incidence in adults: A prospective assessment from the PREDIMED study

Author

Becerra-Tomás, Nerea, Díaz-López, A., Rosique-Esteban, N., Ros, E., Buil-Cosiales, P., Corella, D., Estruch, R., Fitó, Montserrat, Serra-Majem, L., Arós, F., Lamuela-Raventós, Rosa M., Gueto Rubio, M.V., Loma-Osorio, A., Gómez-Gracia, Enrique, Wärnberg, J., Duaso, I., Rovira, M.A., Benítez Pont, R., Perona, Javier S., Bianchi Alba, M., de la Cruz, E., Basora, J., Brau, A., Salas-Salvadó, J., Bonet, M.T., Gómez-Huelgas, R., Guillén, M., Martínez-González, J., Berrade, N., Molina, C., Casas, Ricard, Sáez, G., Guasch-Ferré, Marta, Iglesias, C., Serra-Mir, M., Velasco García, V., Márquez, F., Montero Romero, Emilio, Vila, J., García-García, M., del Hierro, T., Coltell, O., Jurado-Ruíz, Enrique, Cabré, J.J., Romaguera, D., Valero-Barceló, C., García, M., Costa-Vizcaino, J., Altirriba, J., Prieto, R., García-Valdueza, M., Frontera, G., Fiol, F., Ginard, M., Mestres, G., García, Y., Jover, A., Sorlí, M., Ibarrola-Jurado, Nuria, Molina, N., García, J., Salas-Huetos, A., López-Sabater, M.C., Martínez-Lapiscina, E.H., García Pastor, J.A., Sánchez Luque, J.J., González, J.I., Martín, F., Manzano, E., Fanlo-Maresma, M., Viñas, C., Sáiz, C., Galera, A., Churio-Beraza, B., Trias, F., Bestard, F., Extremera-Urabayen, V., de la Torre, Rafael, Medina-Remón, Alexander, Tort, N., Tello, S., Papandreou, C., Verdú, J.M., Sarasa, I., Muñoz-Aguayo, Daniel, Baby, P., Baena, J.M., Paris, F., Ramos, A., Díaz-Benítez, E.M., Francisco, S., Mengual, L., Ruiz-Canela, M., Roura, P., de Diego Salas, J., Castro Dorado, Antonio, Goñi, E., Fernández-Carrión, R., Fernández-Ballart, J., Yuste, M.C., Aldamiz-Echevarría, M., Alonso-Gómez, A.M., Berjón, J., Sanjulián, B., Montañes, D., Forga, L., Schröder, H., Marrugat, J., Llauradó, M., Giménez, F.J., Gallego, J., Vázquez, Z., García-Layana, A., Moñino, M., Larrauri, A., Vinyoles, E., Rovira, A., Guillem-Saiz, P., Eguaras, S., Simón, C., Oller, M., Salaverria, I., Quinzavos, L., Quifer-Rada, P., Parra, L., de Juan, C., Sarmiento de la Fe, F., Liroz, M., Benavent, J., Castellote-Bargalló, Ana I., Farré, M., Baca Osorio, A., Arroyo-Azpa, C., Altés, A., Clos, J., Cofán, M., Valls-Pedret, C., Sala-Vila, A., Sánchez-Tainta, A., Doménech, M., Portolés, Olga, Algorta, J., Pérez-Cabrera, J., Bulló, M., Gil Zarzosa, J., Babio, N., Corbella, Emili, Maestre, E., Munuera, S., Sanz, E., García-Pérez, L., Pedret, R., Isach, A., Vivó, M., Basells, J., Guarner, A., Vizcaino, J., Martín, M. T., Tresserra-Rimbau, A., Castañer, O., Rekondo, J., Díaz-González, B.V., Ruiz-Gutiérrez, Valentina, Carrasco, P., Segarra, R., Álvarez-Pérez, J., Ortega-Azorín, Carolina, Fiol, Miquel, Asensio, E.M., Martínez, P., Tur, J.A., Osma, R., Castillo Anzalas, J.M., Barragán, R., Portu-Zapirain, J., Alonso-Gómez, A., Corbella, X., Coll, L., González-Monje, I., Francés, F., Quiles, L., Pascual, V., Riera, C., Sosa-Also, R.E., Vargas López, E., Pages, M.A., Casañas-Quintana, L.T., Sánchez-Villegas, A., Pérez-Heras, A., Godoy, D., Cabezas, C., Carratalá-Calvo, A., Pla, I., Sánchez-Navarro, S., Boj, J., Santamaría, M.I., Bautista-Castaño, Inmaculada, Proenza, A., Martí, A., Toledo, E., Mata, M., González, R., SerranoMartínez, M., Sánchez, M.S., Díez-Espino, Javier, Santos-Lozano, J.M., Munar, J.A., Timiraus-Fernández, J., García, L., Villanueva-Tellería, J., García-Arellano, A., Cortés-Ugalde, F., Sagredo-Arce, T., Medina-Ponce, J., Vigata-López, M.D., Elosua, R., García Roselló, J., Arceiz Campo, M.T., Amat, J., Urtasun-Samper, A., Frigola, J., Ruano-Rodríguez, C., Amorós, M., Portillo, María P., Flores-Mateo, Gemma, Belló, M.C., Becerra-Tomás, Nerea, Díaz-López, A., Rosique-Esteban, N., Ros, E., Buil-Cosiales, P., Corella, D., Estruch, R., Fitó, Montserrat, Serra-Majem, L., Arós, F., Lamuela-Raventós, Rosa M., Gueto Rubio, M.V., Loma-Osorio, A., Gómez-Gracia, Enrique, Wärnberg, J., Duaso, I., Rovira, M.A., Benítez Pont, R., Perona, Javier S., Bianchi Alba, M., de la Cruz, E., Basora, J., Brau, A., Salas-Salvadó, J., Bonet, M.T., Gómez-Huelgas, R., Guillén, M., Martínez-González, J., Berrade, N., Molina, C., Casas, Ricard, Sáez, G., Guasch-Ferré, Marta, Iglesias, C., Serra-Mir, M., Velasco García, V., Márquez, F., Montero Romero, Emilio, Vila, J., García-García, M., del Hierro, T., Coltell, O., Jurado-Ruíz, Enrique, Cabré, J.J., Romaguera, D., Valero-Barceló, C., García, M., Costa-Vizcaino, J., Altirriba, J., Prieto, R., García-Valdueza, M., Frontera, G., Fiol, F., Ginard, M., Mestres, G., García, Y., Jover, A., Sorlí, M., Ibarrola-Jurado, Nuria, Molina, N., García, J., Salas-Huetos, A., López-Sabater, M.C., Martínez-Lapiscina, E.H., García Pastor, J.A., Sánchez Luque, J.J., González, J.I., Martín, F., Manzano, E., Fanlo-Maresma, M., Viñas, C., Sáiz, C., Galera, A., Churio-Beraza, B., Trias, F., Bestard, F., Extremera-Urabayen, V., de la Torre, Rafael, Medina-Remón, Alexander, Tort, N., Tello, S., Papandreou, C., Verdú, J.M., Sarasa, I., Muñoz-Aguayo, Daniel, Baby, P., Baena, J.M., Paris, F., Ramos, A., Díaz-Benítez, E.M., Francisco, S., Mengual, L., Ruiz-Canela, M., Roura, P., de Diego Salas, J., Castro Dorado, Antonio, Goñi, E., Fernández-Carrión, R., Fernández-Ballart, J., Yuste, M.C., Aldamiz-Echevarría, M., Alonso-Gómez, A.M., Berjón, J., Sanjulián, B., Montañes, D., Forga, L., Schröder, H., Marrugat, J., Llauradó, M., Giménez, F.J., Gallego, J., Vázquez, Z., García-Layana, A., Moñino, M., Larrauri, A., Vinyoles, E., Rovira, A., Guillem-Saiz, P., Eguaras, S., Simón, C., Oller, M., Salaverria, I., Quinzavos, L., Quifer-Rada, P., Parra, L., de Juan, C., Sarmiento de la Fe, F., Liroz, M., Benavent, J., Castellote-Bargalló, Ana I., Farré, M., Baca Osorio, A., Arroyo-Azpa, C., Altés, A., Clos, J., Cofán, M., Valls-Pedret, C., Sala-Vila, A., Sánchez-Tainta, A., Doménech, M., Portolés, Olga, Algorta, J., Pérez-Cabrera, J., Bulló, M., Gil Zarzosa, J., Babio, N., Corbella, Emili, Maestre, E., Munuera, S., Sanz, E., García-Pérez, L., Pedret, R., Isach, A., Vivó, M., Basells, J., Guarner, A., Vizcaino, J., Martín, M. T., Tresserra-Rimbau, A., Castañer, O., Rekondo, J., Díaz-González, B.V., Ruiz-Gutiérrez, Valentina, Carrasco, P., Segarra, R., Álvarez-Pérez, J., Ortega-Azorín, Carolina, Fiol, Miquel, Asensio, E.M., Martínez, P., Tur, J.A., Osma, R., Castillo Anzalas, J.M., Barragán, R., Portu-Zapirain, J., Alonso-Gómez, A., Corbella, X., Coll, L., González-Monje, I., Francés, F., Quiles, L., Pascual, V., Riera, C., Sosa-Also, R.E., Vargas López, E., Pages, M.A., Casañas-Quintana, L.T., Sánchez-Villegas, A., Pérez-Heras, A., Godoy, D., Cabezas, C., Carratalá-Calvo, A., Pla, I., Sánchez-Navarro, S., Boj, J., Santamaría, M.I., Bautista-Castaño, Inmaculada, Proenza, A., Martí, A., Toledo, E., Mata, M., González, R., SerranoMartínez, M., Sánchez, M.S., Díez-Espino, Javier, Santos-Lozano, J.M., Munar, J.A., Timiraus-Fernández, J., García, L., Villanueva-Tellería, J., García-Arellano, A., Cortés-Ugalde, F., Sagredo-Arce, T., Medina-Ponce, J., Vigata-López, M.D., Elosua, R., García Roselló, J., Arceiz Campo, M.T., Amat, J., Urtasun-Samper, A., Frigola, J., Ruano-Rodríguez, C., Amorós, M., Portillo, María P., Flores-Mateo, Gemma, and Belló, M.C.

Abstract

Background & aims: Legumes, a low-energy, nutrient-dense and low glycemic index food, have shown beneficial effects on glycemic control and adiposity. As such, legumes are widely recommended in diabetic diets, even though there is little evidence that their consumption protects against type 2 diabetes. Therefore the aim of the present study was to examine the associations between consumption of total legumes and specific subtypes, and type 2 diabetes risk. We also investigated the effect of theoretically substituting legumes for other protein- or carbohydrate-rich foods. Methods: Prospective assessment of 3349 participants in the PREvención con DIeta MEDiterránea (PREDIMED) study without type 2 diabetes at baseline. Dietary information was assessed at baseline and yearly during follow-up. We used Cox regression models to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs) for type-2 diabetes incidence according to quartiles of cumulative average consumption of total legumes, lentils, chickpeas, dry beans and fresh peas. Results: During a median follow-up of 4.3 years, 266 new cases of type 2 diabetes occurred. Individuals in the highest quartile of total legume and lentil consumption had a lower risk of diabetes than those in the lowest quartile (HR: 0.65; 95% CI: 0.43, 0.96; P-trend = 0.04; and HR: 0.67; 95% CI: 0.46–0.98; P-trend = 0.05, respectively). A borderline significant association was also observed for chickpeas consumption (HR 0.68; 95% CI: 0.46, 1.00; P-trend = 0.06). Substitutions of half a serving/day of legumes for similar servings of eggs, bread, rice or baked potato was associated with lower risk of diabetes incidence. Conclusions: A frequent consumption of legumes, particularly lentils, in the context of a Mediterranean diet, may provide benefits on type 2 diabetes prevention in older adults at high cardiovascular risk. Trial registration: The trial is registered at http://www.controlled-trials.com (ISRCTN35739639). Registration dat

Published
2018

29. A novel strategy to enhance interfacial adhesion in fiber-reinforced calcium phosphate cement

Author

Gallinetti S, Mestres G, Canal Barnils C, Persson C, and Ginebra MP

Subjects
Calcium phosphate cement, Chitosan, Fiber reinforced, Interfacial adhesion, Toughness, Work of fracture, technology, industry, and agriculture
Abstract

Calcium phosphate cements (CPCs) are extensively used as synthetic bone grafts, but their poor toughness limits their use to non-load-bearing applications. Reinforcement through introduction of fibers and yarns has been evaluated in various studies but always resulted in a decrease in elastic modulus or bending strength when compared to the CPC matrix. The aim of the present work was to improve the interfacial adhesion between fibers and matrix to obtain tougher biocompatible fiber-reinforced calcium phosphate cements (FRCPCs). This was done by adding a polymer solution to the matrix, with chemical affinity to the reinforcing chitosan fibers, namely trimethyl chitosan (TMC). The improved wettability and chemical affinity of the chitosan fibers with the TMC in the liquid phase led to an enhancement of the interfacial adhesion. This resulted in an increase of the work of fracture (several hundred-fold increase), while the elastic modulus and bending strength were maintained similar to the materials without additives. Additionally the TMC-modified CPCs showed suitable biocompatibility with an osteoblastic cell line.

Published
2017

30. Influence of Si substitution on the reactivity of a-tricalcium phosphate

Author

Motisuke M, Mestres G, Renó CO, Carrodeguas RG, Zavaglia CAC, and Ginebra MP

Subjects
Calcium phosphate cement, Kinetics, Silicon, a-Tricalcium phosphate
Abstract

Silicon substituted calcium phosphates have been widely studied over the last ten years due to their enhanced osteogenic properties. Notwithstanding, the role of silicon on a-TCP reactivity is not clear yet. Therefore, the aim of this work was to evaluate the reactivity and the properties of Si-a-TCP in comparison to a-TCP. Precursor powders have similar properties regarding purity, particle size distribution and specific surface area, which allowed a better comparison of the Si effects on their reactivity and cements properties. Both Si-a-TCP and a-TCP hydrolyzed to a calcium-deficient hydroxyapatite when mixed with water but their conversion rates were different. Si-a-TCP exhibited a slower setting rate than a-TCP, i.e. k SSA for Si-TCP (0.021gm -2 h -1 ) was almost four times lower than for a-TCP (0.072gm -2 h -1 ). On the other hand, the compressive strength of the CPC resulting from fully reacted Si-a-TCP was significantly higher (12.800.38MPa) than that of a-TCP (11.440.54MPa), due to the smaller size of the entangled precipitated apatite crystals.

Published
2017

31. Potato consumption does not increase blood pressure or incident hypertension in 2 cohorts of Spanish adults

Author

Hu, E.A., Martínez-González, Miguel Ángel, Salas-Salvadó, J., Corella, D., Ros, E., Fitó, Montserrat, García-Rodriguez, A., Estruch, R., Arós, F., Fiol, M., Lapetra, José, Tresserra-Rimbau, A., Amat, J., García Roselló, J., Sanchez-Villegas, A., Álvarez-Pérez, J., Amorós, M., Cervello, T., Díez Benítez, E., Rovira, M.A., Altirriba, J., Sáiz, C., Mata, M., Bautista-Castaño, Inmaculada, Maldonado Díaz, I., Fernández-Rodríguez, M. J., Duaso, I., Becerra-Tomás, Nerea, Trias, F., García, L., Brau, A., Sáez, G., Corbella, E., de Diego Salas, J., Fernández-Montero, A., Yuste, M.C., Prieto, R., Pérez-de-Ciriza, P., Bobe, I., Navajas, Sánchez-Ruiz, D., Schröder, H., Jurado-Ruiz, E., Portillo, M.P., Buil-Cosiales, P., Sarmiendo de la Fe, F., Sánchez Luque, J.J., Ferreira, C., Zazpe, I., Díez-Espino, Javier, Sarasa, I., Sanjulian, B., Marti, A., Sorlí, J.V., Portolés, O., Martínez, J. Alfredo, Baby, P., Ibarrola-Jurado, Nuria, Serrano-Martínez, M., Sánchez-Tainta, A., Fernández-Crehuet, Joaquín, Pascual, V., García-Arellano, A., Fernandez, M., Paris, F., Giménez, F.J., Basteara-Gortari, J., Extremera-Urabayen, J.V., Benítez Pont, R., Viñas, C., Algorta, J., Garcia-Pérez, L., Serra-Majem, L., Bonet, M.T., Riera, C., Arroyo-Azpa, C., Guarner, A., Sola-Larraza, A., Barcena, F., García, Y., Gutiérrez-Bedmar, M., Casas, R., Oreja-Arrayago, C., Lasanta-Sáez, M.J., Mena, G., Francisco, S., Cia-Lecumberri, P., García-Valdueza, M., Diáz, A., Elcarte-Lopez, T., Artal-Moneva, F., Martín, M.T., Vargas López, E., Medina-Remón, A., Iglesias, C., Esparza-López, J.M., Figuerido-Garmendia, E., Cabre, M., Coltell, O., Wärnberg, J., Tabar-Sarrias, J.A., Pages, M.A., Rebholz, C.M., Fernández-Urzainqui, L., Ariz-Arnedo, M.J., San Vicente, J., Martínez, P., Cabeza-Beunza, J.A., Simón, C., Rekondo, J., Sánchez, M.S., Pascual-Pascual, P., Martínez-Mazo, M.D., Arina-Vergara, E., Godoy, D., Ruiz-Gutiérrez, Valentina, Villanueva, P., Quinzavos, L., Manzano, E., Martin, F., de Juan, C., Basells, J., Pla, I., Tur, J.A., Vizcaino, J., Basora-Gallisa, J., Núñez-Córdoba, J.M., Segarra, R., Hernández, P., Araque, M., Giardina, S., Macua-Martínez, T., Gutierrez, E., Toledo, E., Pedret, R., Guasch-Ferré, Marta, Baena, J.M., Pintó, Xavier, Díaz-López, A., Rosique-Esteban, N., Fernández-Ballart, J., Parra, L., Velasco García, V., Balanza, R., Tello, S., Ramos, A., Simón García, C., Vila, J., Altés, A., Proenza, A., de la Torre, Rafael, Muñoz-Aguayo, D., Murillo, C., Fernández-Carrión, R., Rodríguez, M.A., Elosua, R., Tort, N., Casi, A., Falcón Sanabria, I., Marrugat, J., Ruiz-Canela, M., Carratalá-Calvo, A., Mengual, L., Guillem-Saiz, P., Molina, N., Maestre, E., Gómez-Huelgas, R., Corbella, X., Rovira, A., González, R., Castañer, O., Farré, M., Sanz, E., García, J., González-Monje, I., Sánchez-Navarro, S., Carrasco, P., Ortega-Azorín, C., Romaguera, D., Roura, P., Asensio, E.M., Vázquez-Ruiz, Z., Canudas, S., Osma, R., Barragán, R., Muñoz, M.A., Martínez-González, J., Razquin, C., Valero-Barceló, C., Felipe, I., Francés, F., Guillén, M., González, J.I., Macías Gutiérrez, B., Tafalla, M., Bulló, M., Salaverria, I., Loma-Osorio, A., Baca Osorio, A., Munuera, S., Alonso, A., Sorlí, J., Vivó, M., Benitez Pont, R., Llauradó, M., Bestard, F., Montero Romero, Emilio, Molina, C., Munar, J.A., Cofán, M., Papandreou, C., Frontera, G., Coll, L., Quiles, L., Isach, A., Bes-Rastrollo, M., Perona, Javier S., Fiol, F., del Hierro, T., Ginard, M., Jover, A., Liroz, M., Parra-Osés, A., Gómez-Gracia, Enrique, Montull, I., Santos-Lozano, J.M., Ortega-Calvo, M., Valls-Pedret, C., García, M., Leal, M., Gil Zarzosa, J., Rico, A., Serra-Mir, M., Martínez, E., Mellado, L., Babio, N., Santana Santana, A.J., Benavent, J., Miró-Moriano, L., De la Fuente-Arrillaga, C., Oller, M., Domínguez-Espinaco, C., Bianchi Alba, M., Vaquero-Diaz, S., Iglesias, P., Cabezas, C., Sala-Vila, A., de la Cruz, E., Román, P., Corchado, Y., Solis, E., Clos, J., Lozano-Rodríguez, J.M., Mestres, G., García-García, M., Lamuela-Raventós, Rosa M., López-Sabater, M.C., Santamaria, M.I., Salas-Huetos, A., Galera, A., Vinyoles, E., Castellote-Bargalló, A. I., Quifer-Rada, P., Gea, A., Pérez-Heras, A., Doménech, M., Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación (España), and Junta de Andalucía

Subjects
Adult, Male, Pediatrics, medicine.medical_specialty, Diastole, Medicine (miscellaneous), 030204 cardiovascular system & hematology, Mediterranean, 03 medical and health sciences, 0302 clinical medicine, Animal science, Glycemic load, SUN cohort, medicine, Humans, 030212 general & internal medicine, Intervention trial, Prospective cohort study, Potatoes, Generalized estimating equation, Aged, Solanum tuberosum, Aged, 80 and over, Nutrition and Dietetics, Increase blood pressure, business.industry, Incidence (epidemiology), PREDIMED study, Middle Aged, Diet, Blood pressure, Spain, Hypertension, Female, business
Abstract

5 Tablas, Background: Potatoes have a high glycemic load but also antioxidants, vitamins, and minerals. It is unclear what mechanisms are involved in relation to their effect on blood pressure (BP) and hypertension. Objectives: This study aimed to assess the association between potato consumption, BP changes, and the risk of hypertension in 2 Spanish populations. Methods: Separate analyses were performed in PREDIMED (PREvención con DIeta MEDiterránea), a multicenter nutrition intervention trial of adults aged 55-80 y, and the SUN (Seguimiento Universidad de Navarra) project, a prospective cohort made up of university graduates and educated adults with ages (means±SDs) of 42.7±13.3 y for men and 35.1± 10.7 y for women. In PREDIMED, generalized estimating equations adjusted for lifestyle and dietary characteristics were used to assess changes in BP across quintiles of total potato consumption during a 4-y follow-up. Controlled BP values (systolic BP < 140 mm Hg and diastolic BP < 90 mm Hg) during follow-up were also assessed. For SUN, multivariateadjusted HRs for incident hypertension during a mean 6.7-y follow-up were calculated. Results: In PREDIMED, the total potato intake was 81.9 ± 40.6 g/d. No overall differences in systolic or diastolic BP changes were detected based on consumption of potatoes. For total potatoes, the mean difference in change between quintile 5 (highest intake) and quintile 1 (lowest intake) in systolic BP after multivariate adjustment was 20.90 mm Hg (95% CI: -2.56, 0.76 mm Hg; P-trend = 0.1) and for diastolic BP was 20.02 mm Hg (95% CI: -0.93, 0.89 mm Hg; P-trend = 0.8). In SUN, the total potato consumption was 52.7 ± 33.6 g/d, and no significant association between potato consumption and hypertension incidence was observed in the fully adjusted HR for total potato consumption (quintile 5 compared with quintile 1: 0.98; 95% CI: 0.80, 1.19; P-trend = 0.8). Conclusions: Potato consumption is not associated with changes over 4 y in blood pressure among older adults in Spain or with the risk of hypertension among Spanish adults., Supported by the official funding agency for biomedical research of the Spanish Government, Instituto de Salud Carlos III through grants provided to research networks specifically developed for the trial (RTIC G03/140, to RE; RTIC RD 06/0045, to MAM-G) and through Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERobn), and by grants from Centro Nacional de Investigaciones Cardiovasculares (CNIC 06/2007), Fondo de Investigación Sanitaria–Fondo Europeo de Desarrollo Regional [Proyecto de Investigación (PI) 04-2239, PI 05/2584, CP06/00100, PI07/0240, PI07/1138, PI07/0954, PI 07/0473, PI10/01407, PI10/02658, PI11/01647, P11/02505 and PI13/00462], Ministerio de Ciencia e Innovación [Recursos y teconologia agroalimentarias (AGL)-2009-13906-C02 and AGL2010-22319-C03 and AGL2013-49083-C3-1-R], Fundación Mapfre 2010, the Consejería de Salud de la Junta de Andalucía (PI0105/2007), the Public Health Division of the Department of Health of the Autonomous Government of Catalonia, Generalitat Valenciana [Generalitat Valenciana Ayuda Complementaria (GVACOMP) 06109, GVACOMP2010-181, GVACOMP2011-151], Conselleria de Sanitat y AP; Atención Primaria (CS) 2010-AP-111 and CS2011-AP-042, and Regional Government of Navarra (P27/2011).

Published
2017

33. Legume consumption is inversely associated with type 2 diabetes incidence in adults: A prospective assessment from the PREDIMED study

Author

Becerra-Tomás, Nerea, primary, Díaz-López, Andrés, additional, Rosique-Esteban, Núria, additional, Ros, Emilio, additional, Buil-Cosiales, Pilar, additional, Corella, Dolores, additional, Estruch, Ramon, additional, Fitó, Montserrat, additional, Serra-Majem, Lluís, additional, Arós, Fernando, additional, Lamuela-Raventós, Rosa Maria, additional, Fiol, Miquel, additional, Santos-Lozano, José Manuel, additional, Díez-Espino, Javier, additional, Portoles, Olga, additional, Salas-Salvadó, Jordi, additional, Serra-Mir, M., additional, Pérez-Heras, A., additional, Viñas, C., additional, Casas, R., additional, Medina-Renom, A., additional, Baena, J.M., additional, García, M., additional, Oller, M., additional, Amat, J., additional, Duaso, I., additional, García, Y., additional, Iglesias, C., additional, Simón, C., additional, Quinzavos, L., additional, Parra, L., additional, Liroz, M., additional, Benavent, J., additional, Clos, J., additional, Pla, I., additional, Amorós, M., additional, Bonet, M.T., additional, Martín, M.T., additional, Sánchez, M.S., additional, Altirriba, J., additional, Manzano, E., additional, Altés, A., additional, Cofán, M., additional, Valls-Pedret, C., additional, Sala-Vila, A., additional, Doménech, M., additional, Bulló, M., additional, Babio, N., additional, Basora, J., additional, González, R., additional, Molina, C., additional, Márquez, F., additional, Martínez, P., additional, Ibarrola, N., additional, Sorlí, M., additional, García Roselló, J., additional, Castro, A., additional, Martin, F., additional, Tort, N., additional, Isach, A., additional, Guasch-Ferre, M., additional, Cabré, J.J., additional, Mestres, G., additional, Paris, F., additional, Llauradó, M., additional, Pedret, R., additional, Basells, J., additional, Vizcaino, J., additional, Segarra, R., additional, Frigola, J., additional, Costa-Vizcaino, J., additional, Salas-Huetos, A., additional, Boj, J., additional, Montañes, D., additional, Papandreou, Christopher, additional, Fernández-Ballart, J., additional, Carrasco, P., additional, Ortega-Azorín, C., additional, Asensio, E.M., additional, Osma, R., additional, Barragán, R., additional, Francés, F., additional, Guillén, M., additional, González, J.I., additional, Sáiz, C., additional, Portolés, O., additional, Giménez, F.J., additional, Coltell, O., additional, Fernández-Carrión, R., additional, Guillem-Sáiz, P., additional, González-Monje, I., additional, Quiles, L., additional, Pascual, V., additional, Riera, C., additional, Pages, M.A., additional, Godoy, D., additional, Carratalá-Calvo, A., additional, Sánchez-Navarro, S., additional, Valero-Barceló, C., additional, Tello, S., additional, Vila, J., additional, de la Torre, R., additional, Muñoz-Aguayo, D., additional, Elosua, R., additional, Marrugat, J., additional, Schröder, H., additional, Molina, N., additional, Maestre, E., additional, Rovira, A., additional, Castañer, O., additional, Farré, M., additional, Toledo, E., additional, Ruiz-Canela, M., additional, Sanjulián, B., additional, Sánchez-Tainta, A., additional, Eguaras, S., additional, Martí, A., additional, Buil-Cosiales, P., additional, SerranoMartínez, M., additional, Diez-Espino, J., additional, García-Arellano, A., additional, Martínez-Lapiscina, E.H., additional, Goñi, E., additional, Vázquez, Z., additional, Berrade, N., additional, Extremera-Urabayen, V., additional, Arroyo-Azpa, C., additional, García-Pérez, L., additional, Villanueva-Telleria, J., additional, Cortés-Ugalde, F., additional, Sagredo-Arce, T., additional, Vigata-López, M.D., additional, Arceiz Campo, M.T., additional, Urtasun-Samper, A., additional, Gueto Rubio, M.V., additional, Churio-Beraza, B., additional, Arós, F., additional, Salaverria, I., additional, del Hierro, T., additional, Algorta, J., additional, Francisco, S., additional, Alonso-Gómez, A., additional, Sanz, E., additional, Rekondo, J., additional, Belló, M.C., additional, Loma-Osorio, A., additional, Gómez-Gracia, E., additional, Wärnberg, J., additional, Benítez Pont, R., additional, Bianchi Alba, M., additional, Gómez-Huelgas, R., additional, Martínez-González, J., additional, Velasco García, V., additional, de Diego Salas, J., additional, Baca Osorio, A., additional, Gil Zarzosa, J., additional, Sánchez Luque, J.J., additional, Vargas López, E., additional, Ruiz-Gutiérrez, V., additional, Sánchez Perona, J., additional, Montero Romero, E., additional, García-García, M., additional, Jurado-Ruiz, E., additional, Fiol, M., additional, Romaguera, D., additional, García-Valdueza, M., additional, Moñino, M., additional, Munuera, S., additional, Vivó, M., additional, Bestard, F., additional, Munar, J.A., additional, Coll, L., additional, Proenza, A., additional, Prieto, R., additional, Frontera, G., additional, Fiol, F., additional, Ginard, M., additional, Jover, A., additional, García, J., additional, Santos-Lozano, J.M., additional, Ortega-Calvo, M., additional, Mellado, L., additional, García-Corte, F.J., additional, Román, P., additional, Iglesias, P., additional, Corchado, Y., additional, Miró-Moriano, L., additional, Domínguez-Espinaco, C., additional, Lozano-Rodriguez, J.M., additional, Vaquero-Diaz, S., additional, López- Sabater, M.C., additional, Castellote-Bargalló, A.I., additional, Quifer-Rada, P., additional, Tresserra-Rimbau, A., additional, Álvarez-Pérez, J., additional, Díaz-Benítez, E.M., additional, Sánchez-Villegas, A., additional, Casañas-Quintana, L.T., additional, Pérez-Cabrera, J., additional, Ruano-Rodríguez, C., additional, Bautista-Castaño, I., additional, Sarmiento de la Fe, F., additional, García Pastor, J.A., additional, Díaz-González, B.V., additional, Castillo Anzalas, J.M., additional, Sosa-Also, R.E., additional, Medina-Ponce, J., additional, de la Cruz, E., additional, Fanlo-Maresma, M., additional, Galera, A., additional, Trias, F., additional, Sarasa, I., additional, Corbella, E., additional, Corbella, X., additional, Cabezas, C., additional, Vinyoles, E., additional, Rovira, M.A., additional, García, L., additional, Flores, G., additional, Verdú, J.M., additional, Baby, P., additional, Ramos, A., additional, Mengual, L., additional, Roura, P., additional, Yuste, M.C., additional, Guarner, A., additional, Santamaría, M.I., additional, Mata, M., additional, de Juan, C., additional, Brau, A., additional, Tur, J.A., additional, Portillo, M.P., additional, Sáez, G., additional, Aldamiz-Echevarría, M., additional, Alonso-Gómez, A.M., additional, Berjón, J., additional, Forga, L., additional, Gállego, J., additional, García-Layana, A., additional, Larrauri, A., additional, Portu-Zapirain, J., additional, and Timiraus-Fernández, J., additional

Published
2018
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34. Potato consumption does not increase blood pressure or incident hypertension in 2 cohorts of Spanish adults

Author

Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación (España), Junta de Andalucía, Hu, E.A., Martínez-González, Miguel Ángel, Salas-Salvadó, J., Corella, D., Ros, E., Fitó, Montserrat, García-Rodriguez, A., Estruch, R., Arós, F., Fiol, M., Lapetra, José, Asensio, E.M., Vázquez-Ruiz, Z., Canudas, S., Osma, R., Barragán, R., Muñoz, M.A., Martínez-González, J., Razquin, C., Valero-Barceló, C., Rovira, M.A., Tabar-Sarrias, J.A., Felipe, I., Francés, F., Guillén, M., González, J.I., Macías Gutiérrez, B., Tafalla, M., Bulló, M., Salaverria, I., Loma-Osorio, A., Baca Osorio, A., Pages, M.A., Altirriba, J., Munuera, S., Alonso, A., Sorlí, J., Vivó, M., Benitez Pont, R., Llauradó, M., Bestard, F., Montero Romero, Emilio, Molina, C., Rebholz, C.M., Munar, J.A., Sáiz, C., Cofán, M., Papandreou, C., Frontera, G., Coll, L., Quiles, L., Isach, A., Bes-Rastrollo, M., Perona, Javier S., Fernández-Urzainqui, L., Fiol, F., del Hierro, T., Mata, M., Ginard, M., Jover, A., Liroz, M., Parra-Osés, A., García, J., Gómez-Gracia, Enrique, Montull, I., Ariz-Arnedo, M.J., Santos-Lozano, J.M., Ortega-Calvo, M., Valls-Pedret, C., Bautista-Castaño, Inmaculada, García, M., Leal, M., Gil Zarzosa, J., Rico, A., Serra-Mir, M., Martínez, E., San Vicente, J., Mellado, L., Babio, N., Santana Santana, A.J., Benavent, J., Maldonado Díaz, I., Miró-Moriano, L., De la Fuente-Arrillaga, C., Rovira, A., Oller, M., Domínguez-Espinaco, C., Martínez, P., Bianchi Alba, M., Vaquero-Diaz, S., Iglesias, P., Cabezas, C., Sala-Vila, A., Fernández-Rodríguez, M. J., de la Cruz, E., Román, P., Corchado, Y., Solis, E., Cabeza-Beunza, J.A., Clos, J., Lozano-Rodríguez, J.M., Mestres, G., García-García, M., Lamuela-Raventós, Rosa M., López-Sabater, M.C., Duaso, I., Santamaria, M.I., Salas-Huetos, A., Galera, A., Simón, C., Vinyoles, E., Castellote-Bargalló, Ana I., Quifer-Rada, P., Gea, A., Pérez-Heras, A., Doménech, M., Becerra-Tomás, Nerea, Trias, F., García, L., Brau, A., Rekondo, J., Sáez, G., Corbella, Emili, de Diego Salas, J., Fernández-Montero, A., Yuste, M.C., Prieto, R., Pérez-de-Ciriza, P., Bobe, I., Navajas, R., Sánchez-Ruiz, D., Tresserra-Rimbau, A., Schröder, H., Jurado-Ruíz, Enrique, Portillo, María P., Buil-Cosiales, P., Sarmiendo de la Fe, F., Sánchez Luque, J.J., Ferreira, C., Zazpe, I., Díez-Espino, Javier, Sarasa, I., Sánchez, M.S., Sanjulian, B., Marti, A., Sorlí, J.V., Portolés, Olga, Martínez, J. Alfredo, Baby, P., Ibarrola-Jurado, Nuria, Serrano-Martínez, M., Sánchez-Tainta, A., Fernández-Crehuet, Joaquín, Pascual-Pascual, P., Pascual, V., García-Arellano, A., Fernández, M., Paris, F., Giménez, F.J., Basteara-Gortari, J., Extremera-Urabayen, J.V., Benítez Pont, R., Viñas, C., Algorta, J., Martínez-Mazo, M.D., Garcia-Pérez, L., Serra-Majem, L., Bonet, M.T., Riera, C., Arroyo-Azpa, C., Guarner, A., Sola-Larraza, A., Barcena, F., García, Y., Gutiérrez-Bedmar, M., Arina-Vergara, E., Casas, Ricard, Oreja-Arrayago, C., Lasanta-Sáez, M.J., Mena, G., Francisco, S., Cia-Lecumberri, P., García-Valdueza, M., Diáz, A., Elcarte-Lopez, T., Artal-Moneva, F., Godoy, D., Martín, M. T., Vargas López, E., Medina-Remón, Alexander, Iglesias, C., Esparza-López, J.M., Figuerido-Garmendia, E., Cabre, M., Coltell, O., Wärnberg, J., Ruiz-Gutiérrez, Valentina, Villanueva, P., Quinzavos, L., Manzano, E., Martín, F., Amat, J., de Juan, C., Basells, J., Pla, I., Tur, J.A., Vizcaino, J., Basora-Gallisa, J., Núñez-Córdoba, J.M., Segarra, R., Hernández, P., Araque, M., García Roselló, J., Giardina, S., Macua-Martínez, T., Gutierrez, E., Toledo, E., Pedret, R., Guasch-Ferré, Marta, Baena, J.M., Pintó, Xavier, Díaz-López, A., Rosique-Esteban, N., Sanchez-Villegas, A., Fernández-Ballart, J., Parra, L., Velasco García, V., Balanza, R., Tello, S., Ramos, A., Simón García, C., Vila, J., Altés, A., Proenza, A., Álvarez-Pérez, J., de la Torre, Rafael, Muñoz-Aguayo, Daniel, Murillo, C., Fernández-Carrión, R., Rodríguez, M. A., Elosua, R., Tort, N., Casi, A., Falcón Sanabria, I., Marrugat, J., Amorós, M., Ruiz-Canela, M., Carratalá-Calvo, A., Mengual, L., Guillem-Saiz, P., Molina, N., Maestre, E., Gómez-Huelgas, R., Corbella, X., Cervello, T., González, R., Castañer, O., Farré, M., Sanz, E., González-Monje, I., Sánchez-Navarro, S., Carrasco, P., Ortega-Azorín, Carolina, Romaguera, D., Díez Benítez, E., Roura, P., Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación (España), Junta de Andalucía, Hu, E.A., Martínez-González, Miguel Ángel, Salas-Salvadó, J., Corella, D., Ros, E., Fitó, Montserrat, García-Rodriguez, A., Estruch, R., Arós, F., Fiol, M., Lapetra, José, Asensio, E.M., Vázquez-Ruiz, Z., Canudas, S., Osma, R., Barragán, R., Muñoz, M.A., Martínez-González, J., Razquin, C., Valero-Barceló, C., Rovira, M.A., Tabar-Sarrias, J.A., Felipe, I., Francés, F., Guillén, M., González, J.I., Macías Gutiérrez, B., Tafalla, M., Bulló, M., Salaverria, I., Loma-Osorio, A., Baca Osorio, A., Pages, M.A., Altirriba, J., Munuera, S., Alonso, A., Sorlí, J., Vivó, M., Benitez Pont, R., Llauradó, M., Bestard, F., Montero Romero, Emilio, Molina, C., Rebholz, C.M., Munar, J.A., Sáiz, C., Cofán, M., Papandreou, C., Frontera, G., Coll, L., Quiles, L., Isach, A., Bes-Rastrollo, M., Perona, Javier S., Fernández-Urzainqui, L., Fiol, F., del Hierro, T., Mata, M., Ginard, M., Jover, A., Liroz, M., Parra-Osés, A., García, J., Gómez-Gracia, Enrique, Montull, I., Ariz-Arnedo, M.J., Santos-Lozano, J.M., Ortega-Calvo, M., Valls-Pedret, C., Bautista-Castaño, Inmaculada, García, M., Leal, M., Gil Zarzosa, J., Rico, A., Serra-Mir, M., Martínez, E., San Vicente, J., Mellado, L., Babio, N., Santana Santana, A.J., Benavent, J., Maldonado Díaz, I., Miró-Moriano, L., De la Fuente-Arrillaga, C., Rovira, A., Oller, M., Domínguez-Espinaco, C., Martínez, P., Bianchi Alba, M., Vaquero-Diaz, S., Iglesias, P., Cabezas, C., Sala-Vila, A., Fernández-Rodríguez, M. J., de la Cruz, E., Román, P., Corchado, Y., Solis, E., Cabeza-Beunza, J.A., Clos, J., Lozano-Rodríguez, J.M., Mestres, G., García-García, M., Lamuela-Raventós, Rosa M., López-Sabater, M.C., Duaso, I., Santamaria, M.I., Salas-Huetos, A., Galera, A., Simón, C., Vinyoles, E., Castellote-Bargalló, Ana I., Quifer-Rada, P., Gea, A., Pérez-Heras, A., Doménech, M., Becerra-Tomás, Nerea, Trias, F., García, L., Brau, A., Rekondo, J., Sáez, G., Corbella, Emili, de Diego Salas, J., Fernández-Montero, A., Yuste, M.C., Prieto, R., Pérez-de-Ciriza, P., Bobe, I., Navajas, R., Sánchez-Ruiz, D., Tresserra-Rimbau, A., Schröder, H., Jurado-Ruíz, Enrique, Portillo, María P., Buil-Cosiales, P., Sarmiendo de la Fe, F., Sánchez Luque, J.J., Ferreira, C., Zazpe, I., Díez-Espino, Javier, Sarasa, I., Sánchez, M.S., Sanjulian, B., Marti, A., Sorlí, J.V., Portolés, Olga, Martínez, J. Alfredo, Baby, P., Ibarrola-Jurado, Nuria, Serrano-Martínez, M., Sánchez-Tainta, A., Fernández-Crehuet, Joaquín, Pascual-Pascual, P., Pascual, V., García-Arellano, A., Fernández, M., Paris, F., Giménez, F.J., Basteara-Gortari, J., Extremera-Urabayen, J.V., Benítez Pont, R., Viñas, C., Algorta, J., Martínez-Mazo, M.D., Garcia-Pérez, L., Serra-Majem, L., Bonet, M.T., Riera, C., Arroyo-Azpa, C., Guarner, A., Sola-Larraza, A., Barcena, F., García, Y., Gutiérrez-Bedmar, M., Arina-Vergara, E., Casas, Ricard, Oreja-Arrayago, C., Lasanta-Sáez, M.J., Mena, G., Francisco, S., Cia-Lecumberri, P., García-Valdueza, M., Diáz, A., Elcarte-Lopez, T., Artal-Moneva, F., Godoy, D., Martín, M. T., Vargas López, E., Medina-Remón, Alexander, Iglesias, C., Esparza-López, J.M., Figuerido-Garmendia, E., Cabre, M., Coltell, O., Wärnberg, J., Ruiz-Gutiérrez, Valentina, Villanueva, P., Quinzavos, L., Manzano, E., Martín, F., Amat, J., de Juan, C., Basells, J., Pla, I., Tur, J.A., Vizcaino, J., Basora-Gallisa, J., Núñez-Córdoba, J.M., Segarra, R., Hernández, P., Araque, M., García Roselló, J., Giardina, S., Macua-Martínez, T., Gutierrez, E., Toledo, E., Pedret, R., Guasch-Ferré, Marta, Baena, J.M., Pintó, Xavier, Díaz-López, A., Rosique-Esteban, N., Sanchez-Villegas, A., Fernández-Ballart, J., Parra, L., Velasco García, V., Balanza, R., Tello, S., Ramos, A., Simón García, C., Vila, J., Altés, A., Proenza, A., Álvarez-Pérez, J., de la Torre, Rafael, Muñoz-Aguayo, Daniel, Murillo, C., Fernández-Carrión, R., Rodríguez, M. A., Elosua, R., Tort, N., Casi, A., Falcón Sanabria, I., Marrugat, J., Amorós, M., Ruiz-Canela, M., Carratalá-Calvo, A., Mengual, L., Guillem-Saiz, P., Molina, N., Maestre, E., Gómez-Huelgas, R., Corbella, X., Cervello, T., González, R., Castañer, O., Farré, M., Sanz, E., González-Monje, I., Sánchez-Navarro, S., Carrasco, P., Ortega-Azorín, Carolina, Romaguera, D., Díez Benítez, E., and Roura, P.

Abstract

Background: Potatoes have a high glycemic load but also antioxidants, vitamins, and minerals. It is unclear what mechanisms are involved in relation to their effect on blood pressure (BP) and hypertension. Objectives: This study aimed to assess the association between potato consumption, BP changes, and the risk of hypertension in 2 Spanish populations. Methods: Separate analyses were performed in PREDIMED (PREvención con DIeta MEDiterránea), a multicenter nutrition intervention trial of adults aged 55-80 y, and the SUN (Seguimiento Universidad de Navarra) project, a prospective cohort made up of university graduates and educated adults with ages (means±SDs) of 42.7±13.3 y for men and 35.1± 10.7 y for women. In PREDIMED, generalized estimating equations adjusted for lifestyle and dietary characteristics were used to assess changes in BP across quintiles of total potato consumption during a 4-y follow-up. Controlled BP values (systolic BP < 140 mm Hg and diastolic BP < 90 mm Hg) during follow-up were also assessed. For SUN, multivariateadjusted HRs for incident hypertension during a mean 6.7-y follow-up were calculated. Results: In PREDIMED, the total potato intake was 81.9 ± 40.6 g/d. No overall differences in systolic or diastolic BP changes were detected based on consumption of potatoes. For total potatoes, the mean difference in change between quintile 5 (highest intake) and quintile 1 (lowest intake) in systolic BP after multivariate adjustment was 20.90 mm Hg (95% CI: -2.56, 0.76 mm Hg; P-trend = 0.1) and for diastolic BP was 20.02 mm Hg (95% CI: -0.93, 0.89 mm Hg; P-trend = 0.8). In SUN, the total potato consumption was 52.7 ± 33.6 g/d, and no significant association between potato consumption and hypertension incidence was observed in the fully adjusted HR for total potato consumption (quintile 5 compared with quintile 1: 0.98; 95% CI: 0.80, 1.19; P-trend = 0.8). Conclusions: Potato consumption is not associated with changes over 4 y in blood pressure among o

Published
2017

35. Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across different risk strata

Author

Instituto de Salud Carlos III, Centro Nacional de Investigaciones Cardiovasculares (España), Ministerio de Ciencia e Innovación (España), California Walnut Commission, Amor, A.J., Serra-Mir, M., Martínez-González, M.A., Corella, D., Salas-Salvadó, J., Fitó, Montserrat, Estruch, R., Serra-Majem, L., Arós, F., Babio, N., Ros, E., Cofán, M., Lecea, O., Rosique Esteban, N., Valls-Pedret, C., Freitas-Simoes, T.M., Doménech, M., Gilabert, R., Sagredo Arce, T., Bertolín-Muñoz, A., Tresserra-Rimbau, A., Jurado-Ruíz, Enrique, Salaverría, I., Pages, M.A., Cabré, J.J., Mestres, G., Paris, F., Llauradó, M., Pedret, R., Basells, J., Vizcaino, J., Segarra, R., Sacanella, E., Casas, Ricard, Frontera, G., Alonso-Gómez, A., Godoy, D., López-Sabater, M.C., de la Torre, Rafael, del Hierro, T., Hernandez-Alonso, P., Giardina, S., Ferreira-Pego, C., Pérez-Cabrera, J., Papandreou, C., Baby, P., Camacho, L., Toledo, E., Casanas Quintana, T., Carratalá-Calvo, A., Buil-Cosiales, P., Rovira, A., Ruiz-Canela, M., Martínez, J. Alfredo, Fiol, Miquel, Castellote-Bargalló, Ana I., Algorta, J., Álvarez-Pérez, J., Sanjulian, B., Ortega, E., Sánchez-Tainta, A., Díez-Espino, Javier, Sánchez-Villegas, A., Ginard, M., Fiol, F., García-Valdueza, M., Marrugat, J., Schröder, H., Molina, N., Maestre, E., Castañer, O., Farré, M., Sorli, J.V., Ramos, A., García, J., Moñino, M., Santamaría, M.I., Fernández-Rodríguez, M. J., Jover, A., Pérez-Heras, A., Zanon-Moreno, V., Díaz-Benítez, E.M., Carrasco, P., Ortega-Azorín, Carolina, Asensio, E.M., Oller, M., Proenza, A., Osma, R., Bargalló, N., Barragán, R., Francés, F., García, M., Romaguera, D., Guillén, M., Márquez, F., González, J.I., Saiz, C., Portillo, María P., Mengual, L., Viñas, C., Bautista-Castaño, Inmaculada, de Santamaría, L., Portolés, Olga, Giménez, F.J., Coltell, O., Guillem-Saiz, P., Chiva, G., Mata, M., Sorli, M., de Juan, C., Roura, P., Rekondo, J., Belló, M.C., Loma-Osorio, A., Gómez-Gracia, Enrique, Warnberg, J., Benítez Pont, R., Bianchi Alba, M., Gómez-Huelgas, R., Gueto Rubio, M.V., Bulló, M., Sáez, G., Yuste, M.C., Martínez, P., Valderas, P., Brau, A., Martínez-González, J., Velasco García, V., Romero, S., de Diego Salas, J., Razquin, C., Baca Osorio, A., Gil Zarzosa, J., Becerra-Tomás, Nerea, Guarner, A., Sánchez Luque, J.J., Eguaras, S., Vargas López, E., Ruiz-Gutiérrez, Valentina, Ibarrola-Jurado, Nuria, Tur, J.A., García Roselló, J., Perona, Javier S., Vigata López, M.D., Montero Romero, Emilio, García-García, M., Isach, A., Basora, J., González, R., Nissensohn, M., Díaz-González, V., Ruano-Rodríguez, C., Ortiz-Andrelluchi, A.P., Macías Gutiérrez, B., Santana-Santana, A.J., Pintó, Xavier, de la Cruz, E., García-Arellano, A., Mena, G., Marti, A., Salas-Huetos, A., Díaz-López, A., Arceiz Campo, M.T., Arranz, S., Martín, F., Galera, A., Soler, Y., Trias, F., Elosua, R., Sarasa, I., Quiles, L., Padres, E., Corbella, Emili, Muñoz-Aguayo, Daniel, Molina, C., Cabezas, C., Martín-Rillo, M.J., Vinyoles, E., Rovira, M.A., Goñi, E., Urtasun Samper, A., Tort, N., Sola, A., García, L., Baena, J.M., Flores, G., Verdú, J.M., Tello, S., Arroyo-Azpa, C., García-Pérez, L., Vazquez, Z., Amat, J., Duaso, I., García, Y., Iglesias, C., Simón, C., Quinzavos, L., Parra, L., Liroz, M., Pascual, V., García de la Noceda Montoy, M.D., Berrade, N., Llopis-Osorio, E., Vila, J., Villanueva Telleria, J., Benavent, J., Clos, J., Pla, I., Amorós, M., Bonet, M.T., Sanz, E., Extremera-Urabayen, V., Martín, M. T., Prieto, R., Sánchez, M.S., Altirriba, J., Ruiz-Baixauli, J., Cortés Ugalde, F., Manzano, E., Lamuela-Raventós, Rosa M., Altés, A., Sala-Vila, A., Francisco, S., Riera, C., Instituto de Salud Carlos III, Centro Nacional de Investigaciones Cardiovasculares (España), Ministerio de Ciencia e Innovación (España), California Walnut Commission, Amor, A.J., Serra-Mir, M., Martínez-González, M.A., Corella, D., Salas-Salvadó, J., Fitó, Montserrat, Estruch, R., Serra-Majem, L., Arós, F., Babio, N., Ros, E., Cofán, M., Lecea, O., Rosique Esteban, N., Valls-Pedret, C., Freitas-Simoes, T.M., Doménech, M., Gilabert, R., Sagredo Arce, T., Bertolín-Muñoz, A., Tresserra-Rimbau, A., Jurado-Ruíz, Enrique, Salaverría, I., Pages, M.A., Cabré, J.J., Mestres, G., Paris, F., Llauradó, M., Pedret, R., Basells, J., Vizcaino, J., Segarra, R., Sacanella, E., Casas, Ricard, Frontera, G., Alonso-Gómez, A., Godoy, D., López-Sabater, M.C., de la Torre, Rafael, del Hierro, T., Hernandez-Alonso, P., Giardina, S., Ferreira-Pego, C., Pérez-Cabrera, J., Papandreou, C., Baby, P., Camacho, L., Toledo, E., Casanas Quintana, T., Carratalá-Calvo, A., Buil-Cosiales, P., Rovira, A., Ruiz-Canela, M., Martínez, J. Alfredo, Fiol, Miquel, Castellote-Bargalló, Ana I., Algorta, J., Álvarez-Pérez, J., Sanjulian, B., Ortega, E., Sánchez-Tainta, A., Díez-Espino, Javier, Sánchez-Villegas, A., Ginard, M., Fiol, F., García-Valdueza, M., Marrugat, J., Schröder, H., Molina, N., Maestre, E., Castañer, O., Farré, M., Sorli, J.V., Ramos, A., García, J., Moñino, M., Santamaría, M.I., Fernández-Rodríguez, M. J., Jover, A., Pérez-Heras, A., Zanon-Moreno, V., Díaz-Benítez, E.M., Carrasco, P., Ortega-Azorín, Carolina, Asensio, E.M., Oller, M., Proenza, A., Osma, R., Bargalló, N., Barragán, R., Francés, F., García, M., Romaguera, D., Guillén, M., Márquez, F., González, J.I., Saiz, C., Portillo, María P., Mengual, L., Viñas, C., Bautista-Castaño, Inmaculada, de Santamaría, L., Portolés, Olga, Giménez, F.J., Coltell, O., Guillem-Saiz, P., Chiva, G., Mata, M., Sorli, M., de Juan, C., Roura, P., Rekondo, J., Belló, M.C., Loma-Osorio, A., Gómez-Gracia, Enrique, Warnberg, J., Benítez Pont, R., Bianchi Alba, M., Gómez-Huelgas, R., Gueto Rubio, M.V., Bulló, M., Sáez, G., Yuste, M.C., Martínez, P., Valderas, P., Brau, A., Martínez-González, J., Velasco García, V., Romero, S., de Diego Salas, J., Razquin, C., Baca Osorio, A., Gil Zarzosa, J., Becerra-Tomás, Nerea, Guarner, A., Sánchez Luque, J.J., Eguaras, S., Vargas López, E., Ruiz-Gutiérrez, Valentina, Ibarrola-Jurado, Nuria, Tur, J.A., García Roselló, J., Perona, Javier S., Vigata López, M.D., Montero Romero, Emilio, García-García, M., Isach, A., Basora, J., González, R., Nissensohn, M., Díaz-González, V., Ruano-Rodríguez, C., Ortiz-Andrelluchi, A.P., Macías Gutiérrez, B., Santana-Santana, A.J., Pintó, Xavier, de la Cruz, E., García-Arellano, A., Mena, G., Marti, A., Salas-Huetos, A., Díaz-López, A., Arceiz Campo, M.T., Arranz, S., Martín, F., Galera, A., Soler, Y., Trias, F., Elosua, R., Sarasa, I., Quiles, L., Padres, E., Corbella, Emili, Muñoz-Aguayo, Daniel, Molina, C., Cabezas, C., Martín-Rillo, M.J., Vinyoles, E., Rovira, M.A., Goñi, E., Urtasun Samper, A., Tort, N., Sola, A., García, L., Baena, J.M., Flores, G., Verdú, J.M., Tello, S., Arroyo-Azpa, C., García-Pérez, L., Vazquez, Z., Amat, J., Duaso, I., García, Y., Iglesias, C., Simón, C., Quinzavos, L., Parra, L., Liroz, M., Pascual, V., García de la Noceda Montoy, M.D., Berrade, N., Llopis-Osorio, E., Vila, J., Villanueva Telleria, J., Benavent, J., Clos, J., Pla, I., Amorós, M., Bonet, M.T., Sanz, E., Extremera-Urabayen, V., Martín, M. T., Prieto, R., Sánchez, M.S., Altirriba, J., Ruiz-Baixauli, J., Cortés Ugalde, F., Manzano, E., Lamuela-Raventós, Rosa M., Altés, A., Sala-Vila, A., Francisco, S., and Riera, C.

Abstract

Background-The usefulness of cardiovascular disease (CVD) predictive equations in different populations is debatable. We assessed the efficacy of the Framingham-REGICOR scale, validated for the Spanish population, to identify future CVD in participants, who were predefined as being at high-risk in the PREvención con DIeta MEDiterránea (PREDIMED) study-a nutrition-intervention primary prevention trial-and the impact of adherence to the Mediterranean diet on CVD across risk categories. Methods and Results-In a post hoc analysis, we assessed the CVD predictive value of baseline estimated risk in 5966 PREDIMED participants (aged 55-74 years, 57% women; 48% with type 2 diabetes mellitus). Major CVD events, the primary PREDIMED end point, were an aggregate of myocardial infarction, stroke, and cardiovascular death. Multivariate-adjusted Cox regression was used to calculate hazard ratios for major CVD events and effect modification from the Mediterranean diet intervention across risk strata (low, moderate, high, very high). The Framingham-REGICOR classification of PREDIMED participants was 25.1% low risk, 44.5% moderate risk, and 30.4% high or very high risk. During 6-year follow-up, 188 major CVD events occurred. Hazard ratios for major CVD events increased in parallel with estimated risk (2.68, 4.24, and 6.60 for moderate, high, and very high risk), particularly in men (7.60, 13.16, and 15.85, respectively, versus 2.16, 2.28, and 3.51, respectively, in women). Yet among those with low or moderate risk, 32.2% and 74.3% of major CVD events occurred in men and women, respectively. Mediterranean diet adherence was associated with CVD risk reduction regardless of risk strata (P > 0.4 for interaction). Conclusions-Incident CVD increased in parallel with estimated risk in the PREDIMED cohort, but most events occurred in non- high-risk categories, particularly in women. Until predictive tools are improved, promotion of the Mediterranean diet might be useful to reduce CVD indepen

Published
2017

36. Changes in the drug release pattern of fresh and set simvastatin-loaded brushite cement

Author

Mestres G, Kugiejko K, Pastorino D, Unosson J, Öhman C, Karlsson Ott M, Ginebra MP, and Persson C

Subjects
musculoskeletal diseases, surgical procedures, operative, technology, industry, and agriculture, Brushite, Calcium phosphate cement, Local drug release, Setting, Simvastatin, Tortuosity, equipment and supplies
Abstract

Calcium phosphate cements are synthetic bone graft substitutes able to set at physiological conditions. They can be applied by minimally invasive surgery and can also be used as drug delivery systems. Consequently, the drug release pattern from the cement paste (fresh cement) is of high clinical interest. However, previous studies have commonly evaluated the drug release using pre-set cements only. Therefore, the aim of this work was to determine if the time elapsed from cement preparation until immersion in the solution (3 min for fresh cements, and 1h and 15 h for pre-set cements) had an influence on its physical properties, and correlating these to the drug release profile. Simvastatin was selected as a model drug, while brushite cement was used as drug carrier. This study quantified how the setting of a material reduces the accessibility of the release media to the material, thus preventing drug release. A shift in the drug release pattern was observed, from a burst-release for fresh cements to a sustained release for pre-set cements.

Published
2016

37. Impact of Porosity and Electrolyte Composition on the Surface Charge of Hydroxyapatite Biomaterials

Author

Español M, Mestres G, Luxbacher T, Dory JB, and Ginebra MP

Subjects
bone substitute ion adsorption, hydroxyapatite, porosity, streaming current, surface charge, texture, zeta potential
Abstract

The success or failure of a material when implanted in the body is greatly determined by the surface properties of the material and the host tissue reactions. The very first event that takes place after implantation is the interaction of soluble ions, molecules and proteins from the biological environment with the material surface leading to the formation of an adsorbed protein layer that will later influence cell attachment. In this context, the particular topography and surface charge of a material become critical as they influence the nature of the proteins that will adsorb. However, very limited information is available on the surface charge of porous substrates. Only until very recently was the determination of the zeta potential on porous membranes accurately determined. The goal of this work was to implement the previous findings for the determination of the zeta potential of a series of porous hydroxyapatite (HA) substrates and to assess how porosity affects the measurements. In addition, studies using various electrolytes were also performed to prove how the specific affinity of certain ions for HA can further impact surface charge. The results showed that all materials exhibited very similar external surface charge (approximately -23 mV), consistent with their almost identical topographies. However, the presence of interconnected pores underneath the sample surface resulted in an additional internal zeta potential that varied with the porosity content. Measurements with different electrolytes confirmed the selectivity of divalent ions for HA underlying the importance of testing biomaterials using relevant electrolytes.

Published
2016

39. Prediction of Cardiovascular Disease by the Framingham‐REGICOR Equation in the High‐Risk PREDIMED Cohort: Impact of the Mediterranean Diet Across Different Risk Strata

Author

Amor, Antonio J., primary, Serra‐Mir, Mercè, additional, Martínez‐González, Miguel A., additional, Corella, Dolores, additional, Salas‐Salvadó, Jordi, additional, Fitó, Montserrat, additional, Estruch, Ramón, additional, Serra‐Majem, Lluis, additional, Arós, Fernando, additional, Babio, Nancy, additional, Ros, Emilio, additional, Ortega, Emilio, additional, Pérez‐Heras, A., additional, Viñas, C., additional, Casas, R., additional, de Santamaría, L., additional, Romero, S., additional, Sacanella, E., additional, Chiva, G., additional, Valderas, P., additional, Arranz, S., additional, Baena, J. M., additional, García, M., additional, Oller, M., additional, Amat, J., additional, Duaso, I., additional, García, Y., additional, Iglesias, C., additional, Simón, C., additional, Quinzavos, Ll., additional, Parra, Ll., additional, Liroz, M., additional, Benavent, J., additional, Clos, J., additional, Pla, I., additional, Amorós, M., additional, Bonet, M. T., additional, Martin, M. T., additional, Sánchez, M. S., additional, Altirriba, J., additional, Manzano, E., additional, Altés, A., additional, Sala‐Vila, A., additional, Cofán, M., additional, Valls‐Pedret, C., additional, Freitas‐Simoes, T. M., additional, Doménech, M., additional, Gilabert, R., additional, Bargalló, N., additional, Bulló, M., additional, Basora, J., additional, González, R., additional, Díaz‐López, A., additional, Molina, C., additional, Mena, G., additional, Márquez, F., additional, Martínez, P., additional, Ibarrola, N., additional, Sorli, M., additional, García Roselló, J., additional, Martín, F., additional, Tort, N., additional, Isach, A., additional, Salas‐Huetos, A., additional, Becerra‐Tomás, N., additional, Rosique Esteban, N., additional, Cabré, J. J., additional, Mestres, G., additional, Paris, F., additional, Llaurado, M., additional, Pedret, R., additional, Basells, J., additional, Vizcaino, J., additional, Segarra, R., additional, Hernandez‐Alonso, P., additional, Giardina, S., additional, Ferreira‐Pego, C., additional, Papandreou, C., additional, Camacho, L., additional, Toledo, E., additional, Buil‐Cosiales, P., additional, Ruiz‐Canela, M., additional, Martínez, J. A., additional, Sanjulian, B., additional, Sánchez‐Tainta, A., additional, Diez‐Espino, J., additional, Razquin, C., additional, Garcia‐Arellano, A., additional, Goni, E., additional, Vazquez, Z., additional, Berrade, N., additional, Extremera‐Urabayen, V., additional, Eguaras, S., additional, Marti, A., additional, Arroyo‐Azpa, C., additional, García‐Pérez, L., additional, Villanueva Telleria, J., additional, Cortés Ugalde, F., additional, Sagredo Arce, T., additional, de la Noceda Montoy, M. D. García, additional, Vigata López, M. D., additional, Arceiz Campo, M. T., additional, Urtasun Samper, A., additional, Gueto Rubio, M. V., additional, Sola, A., additional, Goñi, N., additional, Lecea, O., additional, Tello, S., additional, Vila, J., additional, de la Torre, R., additional, Muñoz‐Aguayo, D., additional, Elosua, R., additional, Marrugat, J., additional, Schröder, H., additional, Molina, N., additional, Maestre, E., additional, Castañer, O., additional, Rovira, A., additional, Farre, M., additional, Sorli, J. V., additional, Zanon‐Moreno, V., additional, Carrasco, P., additional, Ortega‐Azorín, C., additional, Asensio, E. M., additional, Osma, R., additional, Barragán, R., additional, Francés, F., additional, Guillén, M., additional, González, J. I., additional, Saiz, C., additional, Portolés, O., additional, Giménez, F. J., additional, Coltell, O., additional, Guillem‐Saiz, P., additional, Quiles, L., additional, Pascual, V., additional, Riera, C., additional, Pages, M. A., additional, Godoy, D., additional, Carratala‐Calvo, A., additional, Martín‐Rillo, M. J., additional, Llopis‐Osorio, E., additional, Ruiz‐Baixauli, J., additional, Bertolín‐Muñoz, A., additional, Salaverría, I., additional, del Hierro, T., additional, Algorta, J., additional, Francisco, S., additional, Alonso‐Gómez, A., additional, Sanz, E., additional, Rekondo, J., additional, Bello, M. C., additional, Loma‐Osorio, A., additional, Gómez‐Gracia, E., additional, Warnberg, J., additional, Benítez Pont, R., additional, Bianchi Alba, M., additional, Gómez‐Huelgas, R., additional, Martínez‐González, J., additional, Velasco García, V., additional, de Diego Salas, J., additional, Baca Osorio, A., additional, Gil Zarzosa, J., additional, Sánchez Luque, J. J., additional, Vargas López, E., additional, Ruiz‐Gutiérrez, V., additional, Sánchez Perona, J., additional, Montero Romero, E., additional, García‐García, M., additional, Jurado‐Ruiz, E., additional, Fiol, M., additional, García‐Valdueza, M., additional, Moñino, M., additional, Proenza, A., additional, Prieto, R., additional, Frontera, G., additional, Ginard, M., additional, Fiol, F., additional, Jover, A., additional, Romaguera, D., additional, García, J., additional, Lapetra, J., additional, Santos‐Lozano, J. M., additional, Ortega‐Calvo, M., additional, Mellado, L., additional, Leal, M., additional, Martínez, E., additional, José García, F., additional, Román, P., additional, Iglesias, P., additional, Corchado, Y., additional, Miró, L., additional, Domínguez, C., additional, Lozano, J. M., additional, Mayoral, E., additional, Lamuela‐Raventós, R. M., additional, López‐Sabater, M. C., additional, Castellote‐Bargallo, A. I., additional, Tresserra‐Rimbau, A., additional, Álvarez‐Pérez, J., additional, Díaz‐Benítez, E. M., additional, Bautista Castaño, I., additional, Sánchez‐Villegas, A., additional, Fernández‐Rodríguez, M. J., additional, Casanas Quintana, T., additional, Pérez‐Cabrera, J., additional, Nissensohn, M., additional, Díaz‐González, V., additional, Ruano‐Rodríguez, C., additional, Ortiz‐Andrelluchi, A. P., additional, Macías Gutiérrez, B., additional, Santana‐Santana, A. J., additional, Pintó, X., additional, de la Cruz, E., additional, Galera, A., additional, Soler, Y., additional, Trias, F., additional, Sarasa, I., additional, Padres, E., additional, Corbella, E., additional, Cabezas, C., additional, Vinyoles, E., additional, Rovira, M. A., additional, García, L., additional, Flores, G., additional, Verdú, J. M., additional, Baby, P., additional, Ramos, A., additional, Mengual, L., additional, Roura, P., additional, Yuste, M. C., additional, Guarner, A., additional, Santamaría, M. I., additional, Mata, M., additional, de Juan, C., additional, Brau, A., additional, Tur, J. A., additional, Portillo, M. P., additional, Sáez, G., additional, Aldamiz, M., additional, Alonso, A., additional, Berjón, J., additional, Forga, L., additional, Gallego, J., additional, Larrauri, A., additional, Portu, J., additional, Timiraos, J., additional, and Serrano‐Martínez, M., additional

Published
2017
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40. Inflammatory response to nano- and microstructured hydroxyapatite

Author

Mestres G, Español M, Xia W, Persson C, Ginebra MP, and Ott MK

Abstract

The proliferation and activation of leukocytes upon contact with a biomaterial play a crucial role in the degree of inflammatory response, which may then determine the clinical failure or success of an implanted biomaterial. The aim of this study was to evaluate whether nano- and microstructured biomimetic hydroxyapatite substrates can influence the growth and activation of macrophage-like cells. Hydroxyapatite substrates with different crystal morphologies consisting of an entangled network of plate-like and needle-like crystals were evaluated. Macrophage proliferation was evaluated on the material surface (direct contact) and also in extracts i.e. media modified by the material (indirect contact). Additionally, the effect of supplementing the extracts with calcium ions and/or proteins was investigated. Macrophage activation on the substrates was evaluated by quantifying the release of reactive oxygen species and by morphological observations. The results showed that differences in the substrate's microstructure play a major role in the activation of macrophages as there was a higher release of reactive oxygen species after culturing the macrophages on plate-like crystals substrates compared to the almost non-existent release on needle-like substrates. However, the difference in macrophage proliferation was ascribed to different ionic exchanges and protein adsorption/retention from the substrates rather than to the texture of materials.

Published
2015

44. Solutions, suspensions et émulsions destinées aux voies orale, parentérale et ophtalmique

Author

Degobert, Ghania, Chambin, Odile, didja, amdidouche -hussein, Marti-Mestres, G., Rosilio, Véronique, patrice, sebert, Skiba, Mohamed, Zerrouk, Naima, Fessi, H., Laboratoire d'automatique et de génie des procédés (LAGEP), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École Supérieure Chimie Physique Électronique de Lyon-Centre National de la Recherche Scientifique (CNRS), Université de Lyon, Procédés Alimentaires et Microbiologiques [Dijon] (PAM), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, Physico-chimie, pharmacotechnie, biopharmacie (PCPB), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Pharmacie Galénique (LPG), Université Paris Descartes - Paris 5 (UPD5), Maloine, Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Université Bourgogne Franche-Comté [COMUE] (UBFC), and DEGOBERT, GHANIA

Subjects
[SDV.SP] Life Sciences [q-bio]/Pharmaceutical sciences, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2007

45. DIALYSIS VASCULAR ACCESS

Author

Fontsere, N., primary, Mestres, G., additional, Burrel, M., additional, Barrufet, M., additional, Montana, X., additional, Arias, M., additional, Ojeda, R., additional, Maduell, F., additional, Campistol, J. M., additional, Nagaraja, P., additional, Rees, D., additional, Husein, T., additional, Chess, J., additional, Lin, C.-C., additional, Yang, W.-C., additional, Khosravi, M., additional, Kandil, H., additional, Cross, J., additional, Hopkins, S., additional, Collier, S., additional, Lopes, D., additional, Pereira, S., additional, Gomes, A. M., additional, Ventura, A., additional, Martins, V., additional, Seabra, J., additional, Rothuizen, T. C., additional, Damanik, F., additional, Visser, M. J. T., additional, Lavrijsen, T., additional, Cox, M. A. J., additional, Moroni, L., additional, Rabelink, T. J., additional, Rotmans, J. I., additional, Fontsere, N., additional, Cardozo, C., additional, Donate, J., additional, Soriano, A., additional, Muros, M., additional, Pons, M., additional, Mensa, J., additional, Navarro-Gonzalez, J. F., additional, Wijewardane, A., additional, Murley, A., additional, Powers, S., additional, Allen, C., additional, Baharani, J., additional, Wilmink, T., additional, Esenturk, M., additional, Zengin, M., additional, Dal, M., additional, Tahtal , N., additional, Shibata, K., additional, Shinzato, T., additional, Satta, H., additional, Nishihara, M., additional, Koguchi, N., additional, Kuji, T., additional, Kawata, S., additional, Kaneda, T., additional, Yasuda, G., additional, Scrivano, J., additional, Pettorini, L., additional, Rutigliano, T., additional, Ciavarella, G. M., additional, De Biase, L., additional, Punzo, G., additional, Mene, P., additional, Pirozzi, N., additional, El Haggan, W., additional, Belazrague, K., additional, Ehoussou, S., additional, Foucher, V., additional, El Salhy, M., additional, Ouellet, G., additional, Davis, J., additional, Caron, P., additional, Leblanc, M., additional, Romitelli, F., additional, Fazzari, L., additional, Ortu, G., additional, Di Stasio, E., additional, Loizzo, G., additional, Vigano, S. M., additional, Bacchini, G., additional, Rocchi, E., additional, Sala, V., additional, Pontoriero, G., additional, Letachowicz, K., additional, Go  biowski, T., additional, Kusztal, M., additional, Letachowicz, W., additional, Weyde, W., additional, Klinger, M., additional, Hollingsworth, L., additional, Roca-Tey, R., additional, Samon, R., additional, Ibrik, O., additional, Roda, A., additional, Gonzalez-Oliva, J. C., additional, Martinez-Cercos, R., additional, Viladoms, J., additional, Renaud, C. J., additional, Lim, E. K., additional, Seow, T. Y., additional, Teh, H. S., additional, Tosic, J., additional, Jankovic, A., additional, Djuric, P., additional, Radovic Maslarevic, V., additional, Popovic, J., additional, Dimkovic, N., additional, Kazantzi, A., additional, Trigka, K., additional, Buono, F., additional, Laurino, S., additional, Toriello, G., additional, Di Luccio, R., additional, Galise, A., additional, Kim, Y. O., additional, Yoon, S. A., additional, Kim, Y. S., additional, Choi, S. J., additional, Min, J. W., additional, Cheong, M. A., additional, Asano, M., additional, Oguchi, K., additional, Saito, A., additional, Onishi, Y., additional, Yamamoto, Y., additional, Fukuhara, S., additional, Akiba, T., additional, Akizawa, T., additional, Kurokawa, K., additional, Guedes Marques, M., additional, Ibeas, J., additional, Maia, P., additional, Ponce, P., additional, Chang, K. Y., additional, Park, H. S., additional, Kim, H. W., additional, Choi, B. S., additional, Park, C. W., additional, Yang, C. W., additional, Jin, D. C., additional, Likaj, E., additional, Seferi, S., additional, Caco, G., additional, Petrela, E., additional, Barbullushi, M., additional, Idrizi, A., additional, Thereska, N., additional, Lomonte, C., additional, Casucci, F., additional, Libutti, P., additional, Lisi, P., additional, Basile, C., additional, Ancarani, P., additional, Valsuani, G., additional, Cavallo, L., additional, Parodi, D., additional, Lorusso, C., additional, Renaud, C., additional, Lai, B. C., additional, Tho, S., additional, Yeoh, L., additional, Botelho, C., additional, Yankovoy, A., additional, Alexandr, S., additional, Smoliacov, A., additional, Stepanov, V., additional, Parker, C., additional, Davies, P., additional, Taylor, S., additional, Mikhail, A., additional, Gubensek, J., additional, Persic, V., additional, Vajdic, B., additional, Ponikvar, R., additional, Buturovic-Ponikvar, J., additional, Hadimeri, U., additional, Warme, A. V., additional, Stegmayr, B., additional, Suvakov, S., additional, Damjanovic, T., additional, Bajcetic, S., additional, Radovic-Maslarevic, V., additional, Simic, T., additional, Rroji, M., additional, Chua, H. L., additional, Kanda, H., additional, See, S. L., additional, Liew, N. C., additional, Tsuchida, K., additional, Tomo, T., additional, Fukasawa, M., additional, Kawashima, S., additional, Minakuchi, J., additional, Thanaraj, V., additional, Dhaygude, A., additional, Ikeda, K., additional, Forneris, G., additional, Cecere, P., additional, Pozzato, M., additional, Trogolo, M., additional, Vallero, A., additional, Mesiano, P., additional, Roccatello, D., additional, Keskin, L., additional, Casey, J. R., additional, Hanson, C. S., additional, Winkelmayer, W. C., additional, Craig, J., additional, Palmer, S., additional, Strippoli, G., additional, Tong, A., additional, Ferrara, D., additional, Scamarda, S., additional, Bernardino, L., additional, Amico, L., additional, Lorito, M. C., additional, Incalcaterra, f., additional, Visconti, L., additional, Visconti, G., additional, Valenza, F., additional, D'Amato, F., additional, Di Napoli, A., additional, Tazza, L., additional, Chicca, S., additional, Lapucci, E., additional, Silvestri, P., additional, Di Lallo, D., additional, Michelozzi, P., additional, and Davoli, M., additional

Published
2014
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46. Apropiación/expropiación de territorialidades sociales. Análisis comparativo de procesos de erradicación/relocalización de fracciones sociales empobrecidas, en ciudades argentinas

Author

Núñez, Ana Estela, Ciuffolini, María Alejandra, Avalle, Gerardo, De la Vega Avila Tulián, Candela, Job, Sergio Fernando, Villegas Guzmán, Sabrina María, Brandán Zehnder, María Gabriela, Hernández, Juliana, Ferrero, María Mercedes, Ibáñez Mestres, G., Gallego, Ayelén, Núñez, Ana Estela, Ciuffolini, María Alejandra, Avalle, Gerardo, De la Vega Avila Tulián, Candela, Job, Sergio Fernando, Villegas Guzmán, Sabrina María, Brandán Zehnder, María Gabriela, Hernández, Juliana, Ferrero, María Mercedes, Ibáñez Mestres, G., and Gallego, Ayelén

Abstract

Las dinámicas de la intervención estatal es un tema intensamente trabajado y, en consecuencia, exige definir con claridad la posición que adoptamos. Las políticas públicas son el modo más visible de las formas que adopta la estatalidad y del modo como concibe y se relaciona con la ciudadanía. Ciertamente, las lógicas impuestas desde hace más de tres décadas han favorecido, con sus esquemas focalizados y meritocráticos, la nítida constitución de sectores sociales objeto de la atención estatal. Ello redunda en una representación cada vez más extendida de una sociedad en la que algunos sectores tienen y ejercen sus derechos, mientras otros sólo serían carentes y asistidos. Esta preocupante situación se ve claramente reforzada por los modos de intervención que los aparatos del Estado vienen desarrollando en materia de política urbana -en general- y en vivienda social -en particular- a través de programas sustentados en la construcción, material y simbólica, de verdaderas fronteras estigmatizantes. En este marco, el problema que propone esta investigación refiere a ¿qué relaciones sociales se ocultan, se construyen y destruyen tras la materialidad de los objetos que se producen y circulan por y con el acceso a una vivienda digna? Empíricamente, abordaremos el análisis sincrónico y diacrónico de los procesos de erradicación/relocalización de fracciones sociales empobrecidas y los programas de vivienda que los tendrían como destinatarios, beneficiarios, adjudicatarios -y no como sujetos de derecho- a través de estudios de caso, en distintas ciudades argentinas (Córdoba, Mar del Plata y Santa Fe). El interés central de dicho estudio, es visibilizar un conjunto de acciones con fuerte contenido biopolítico, pues se nos presentan como dispositivos que naturalizan y legitiman formas diferenciales de apropiación de la ciudad, y formas de violencia implícitas y explícitas. Así, será posible reflexionar y avanzar en la comprensión de ¿Cómo y qué sujetos se construyen con los dispo, Fil: Ciuffolini, María Alejandra. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; Argentina, Fil: Avalle, Gerardo. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; Argentina

Published
2012

47. Territorios en disputa. Un estudio sobre los conflictos territoriales urbanos y rurales en la provincia de Córdoba

Author

Ciuffolini, María Alejandra, Avalle, Gerardo, De la Vega Avila Tulián, Candela, Hernández, Juliana, Job, Sergio Fernando, Bandán Zehnder, Ma. G., Ferrero, María Mercedes, Guzmán, Sabrina, Gallego, Ayelén, Alonso, María Cecilia, Ibáñez Mestres, G., Kantor, D., Vera, F., Feldmann, Noelia, Graglia, Leandro Emilio, Gallo, Erika, Machado Ibars, Milena Marlene, Carrizo Bertuzzi, Tamara, Saccucci, Erika, Rigi Luperti, A., Pares, Facundo, Reyes Tejada, N., Liberal, C., Gatica, Santiago, Vanini, Natalia, Ávila Castro, María Paula, Pleitavino, Guillermo, Ciuffolini, María Alejandra, Avalle, Gerardo, De la Vega Avila Tulián, Candela, Hernández, Juliana, Job, Sergio Fernando, Bandán Zehnder, Ma. G., Ferrero, María Mercedes, Guzmán, Sabrina, Gallego, Ayelén, Alonso, María Cecilia, Ibáñez Mestres, G., Kantor, D., Vera, F., Feldmann, Noelia, Graglia, Leandro Emilio, Gallo, Erika, Machado Ibars, Milena Marlene, Carrizo Bertuzzi, Tamara, Saccucci, Erika, Rigi Luperti, A., Pares, Facundo, Reyes Tejada, N., Liberal, C., Gatica, Santiago, Vanini, Natalia, Ávila Castro, María Paula, and Pleitavino, Guillermo

Abstract

El territorio es el resultado de un conjunto de dispositivos -políticos, económicos, culturales- y de disposiciones sociales que, en su concurrencia y/o contradicción, configuran tanto identidades y campos de comportamiento posibles, como un particular modo de producir y relacionarse con la naturaleza. Entendido así, el territorio y sus posibilidades son el resultado de relaciones de fuerza desplegadas en torno al control y posesión de recursos sociales, económicos, naturales, etc. Estas fuerzas condensan en una específica -es decir histórica- partición del territorio y en formas también específicas de distribución y jerarquización de los elementos y sujetos dispuestos en él. Esto implica pensar el territorio no solamente como dominio del Estado que lo administra, ordena y controla, sino también como resultante de los imperativos del capital, y como espacio de conflictos y resistencias. Se trata de una mirada que, sin descuidar esas dos dimensiones -accionar estatal y accionar del capital- privilegia enfocar el análisis del territorio a partir de conflictos que en él se desatan, entre los modos y prácticas de intervención del Estado, las intervenciones del capital y las resistencias y luchas que la población residente entabla frente o a partir de ellos. En este marco, el interés de este proyecto es analizar los distintos conflictos en torno a la tierra, sus usos y disposición en la provincia de Córdoba, a fin de conocer: la configuración de los conflictos; la confluencia de políticas; los proyectos, intereses, y obstáculos de desarrollo territorial. Su concreción nos permitirá acceder a una última instancia de observación y elaboración propuestas de gestión e intervención sobre los territorios que tengan en cuenta la participación y los intereses de las comunidades involucradas. La hipótesis de trabajo que orienta nuestra propuesta de estudio sostiene que los modos de intervención del Estado y el capital tienen fuerte contenido performativo de los espacios sociales, Fil: Ciuffolini, María Alejandra. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; Argentina, Fil: Avalle, Gerardo. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; Argentina

Published
2012

48. La construcción política de la desigualdad : pobreza y sexualidad en las políticas públicas de la provincia de Córdoba

Author

Ciuffolini, María Alejandra, Avalle, Gerardo, De la Vega Avila Tulián, Candela, Hernández, Juliana, Job, Sergio Fernando, Bandán Zehnder, Ma. G., Ferrero, María Mercedes, Villegas Guzmán, Sabrina María, Gallego, Ayelén, Alonso, María Cecilia, Ibáñez Mestres, G., Kantor, D., Vera, F., Graglia, Edirado, Gallo, Erika, Machado Ibars, Milena Marlene, Carrizo Bertuzzi, Tamara, Saccucci, Erika, Rigi Luperti, A., Pares, Facundo, Reyes Tejada, N., Liberal, C., Gatica, Santiago, Vanini, Natalia, Ávila Castro, María Paula, Pleitavino, Guillermo, Ciuffolini, María Alejandra, Avalle, Gerardo, De la Vega Avila Tulián, Candela, Hernández, Juliana, Job, Sergio Fernando, Bandán Zehnder, Ma. G., Ferrero, María Mercedes, Villegas Guzmán, Sabrina María, Gallego, Ayelén, Alonso, María Cecilia, Ibáñez Mestres, G., Kantor, D., Vera, F., Graglia, Edirado, Gallo, Erika, Machado Ibars, Milena Marlene, Carrizo Bertuzzi, Tamara, Saccucci, Erika, Rigi Luperti, A., Pares, Facundo, Reyes Tejada, N., Liberal, C., Gatica, Santiago, Vanini, Natalia, Ávila Castro, María Paula, and Pleitavino, Guillermo

Abstract

El proyecto pretende analizar la definición de políticas públicas sobre pobreza y ambiente como instancias de visibilización de posiciones y discursividades en conflicto sobre la (des)igualdad. Asimismo pretende entender la formulación de políticas públicas como instancias en que los Estados institucionalizan una definición sobre la (des)igualdad que muchas veces, paradójicamente, resulta en la instauración de exclusiones y el fortalecimiento de regímenes de dominación. Entre las diversas hipótesis que guían el proyecto la más abarcativa sostiene que las decisiones, los modos y campos de intervención definidos en la política pública constituyen en sí mismos un espacio discursivo en el que se establecen definiciones y plasman matrices ideológicas respecto de la (des)igualdad. Pues a partir de ellos se visibilizan operaciones específicas de inclusión/exclusión, igualdad/desigualdad, prohibición/habilitación, etc.; se identifican y caracterizan sujetos; así como también un determinado orden normativo de relaciones y prácticas. No obstante encontrarse legalmente instituida la igualdad como principio subyacente a todo el ordenamiento de derechos, en la práctica las desigualdades se hacen patentes. Éstas son especialmente relevantes en tres áreas de políticas públicas: el trabajo, el hábitat y sexualidad. Consecuentemente, se propone 1. analizar el dispositivo de regulación tal como se materializa en las decisiones, leyes y políticas públicas del Estado Provincial; 2. Esclarecer las disputas y/o articulaciones de orientaciones y prácticas de distintos ámbitos institucionales –expresamente referimos al conjunto de actores que se activan y pujan frente al contenido y carácter de las decisiones públicas; 3. estudiar las prácticas de resistencia frente a las regulaciones instituidas., Fil: Ciuffolini, María Alejandra. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; Argentina, Fil: Avalle, Gerardo. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; Argentina

Published
2012

49. La construcción política de la desigualdad : Pobreza y Sexualidad en las políticas públicas de la Provincia de Córdoba

Author

Ciuffolini, María Alejandra, Avalle, Gerardo, De la Vega Avila Tulián, Candela, Ibaña, Griselda Beatriz, Hernández, Juliana, Job, Sergio Fernando, Bandán Zehnder, Ma. G., Ferrero, María Mercedes, Villegas Guzmán, Sabrina María, Alonso, María Cecilia, Ibáñez Mestres, G., Kantor, D., Gallego, Ayelén, Vera, F., Graglia, Leandro Emilio, Gallo, Erika, Machado Ibars, Milena Marlene, Monte, E., Carrizo Bertuzzi, Tamara, Saccucci, Erika, Rigi Luperti, A., Pares, Facundo, Reyes Tejada, N., Liberal, C., Ciuffolini, María Alejandra, Avalle, Gerardo, De la Vega Avila Tulián, Candela, Ibaña, Griselda Beatriz, Hernández, Juliana, Job, Sergio Fernando, Bandán Zehnder, Ma. G., Ferrero, María Mercedes, Villegas Guzmán, Sabrina María, Alonso, María Cecilia, Ibáñez Mestres, G., Kantor, D., Gallego, Ayelén, Vera, F., Graglia, Leandro Emilio, Gallo, Erika, Machado Ibars, Milena Marlene, Monte, E., Carrizo Bertuzzi, Tamara, Saccucci, Erika, Rigi Luperti, A., Pares, Facundo, Reyes Tejada, N., and Liberal, C.

Abstract

El proyecto pretende analizar la definición de políticas públicas sobre pobreza y ambiente como instancias de visibilización de posiciones y discursividades en conflicto sobre la (des)igualdad. Asimismo pretende entender la formulación de políticas públicas como instancias en que los Estados institucionalizan una definición sobre la (des)igualdad que muchas veces, paradójicamente, resulta en la instauración de exclusiones y el fortalecimiento de regímenes de dominación. Entre las diversas hipótesis que guían el proyecto la más abarcativa sostiene que las decisiones, los modos y campos de intervención definidos en la política pública constituyen en sí mismos un espacio discursivo en el que se establecen definiciones y plasman matrices ideológicas respecto de la (des)igualdad. Pues a partir de ellos se visibilizan operaciones específicas de inclusión/exclusión, igualdad/desigualdad, prohibición/habilitación, etc.; se identifican y caracterizan sujetos; así como también un determinado orden normativo de relaciones y prácticas. No obstante encontrarse legalmente instituida la igualdad como principio subyacente a todo el ordenamiento de derechos, en la práctica las desigualdades se hacen patentes. Éstas son especialmente relevantes en tres áreas de políticas públicas: el trabajo, el hábitat y sexualidad. Consecuentemente, se propone: 1. analizar el dispositivo de regulación tal como se materializa en las decisiones, leyes y políticas públicas del Estado Provincial; 2. Esclarecer las disputas y/o articulaciones de orientaciones y prácticas de distintos ámbitos institucionales –expresamente referimos al conjunto de actores que se activan y pujan frente al contenido y carácter de las decisiones públicas; 3. estudiar las prácticas de resistencia frente a las regulaciones instituidas., Fil: Ciuffolini, María Alejandra. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; Argentina, Fil: Avalle, Gerardo. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; Argentina, Fil: Ibaña, Griselda Beatriz. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; Argentina

Published
2010

50. Gestión de la vida : políticas públicas y conflicto en el uso del territorio y los recursos naturales

Author

Ciuffolini, María Alejandra, Avalle, Gerardo, De la Vega Avila Tulián, Candela, Ibaña, Griselda Beatriz, Hernández, Juliana, Job, Sergio Fernando, Bandán Zehnder, Ma. G., Ferrero, María Mercedes, Villegas Guzmán, Sabrina María, Alonso, María Cecilia, Ibáñez Mestres, G., Kantor, D., Gallego, Ayelén, Vera, F., Graglia, Leandro Emilio, Gallo, Erika, Machado Ibars, Milena Marlene, Monte, E., Carrizo Bertuzzi, Tamara, Saccucci, Erika, Rigi Luperti, A., Pares, Facundo, Reyes Tejada, N., Ciuffolini, María Alejandra, Avalle, Gerardo, De la Vega Avila Tulián, Candela, Ibaña, Griselda Beatriz, Hernández, Juliana, Job, Sergio Fernando, Bandán Zehnder, Ma. G., Ferrero, María Mercedes, Villegas Guzmán, Sabrina María, Alonso, María Cecilia, Ibáñez Mestres, G., Kantor, D., Gallego, Ayelén, Vera, F., Graglia, Leandro Emilio, Gallo, Erika, Machado Ibars, Milena Marlene, Monte, E., Carrizo Bertuzzi, Tamara, Saccucci, Erika, Rigi Luperti, A., Pares, Facundo, and Reyes Tejada, N.

Abstract

Las (des)igualdades, sus orígenes y sus efectos han sido desde siempre una preocupación para la construcción de una política democrática, e incluso una prioridad, al menos así declarada, en las agendas de los Estados. El presente proyecto hace foco en aquellas leyes y políticas públicas que buscan intervenir en el particular campo de las desigualdades emergentes de los usos sociales y económicos del territorio y de los recursos naturales. Actualmente, las provincias de Catamarca, Córdoba y La Rioja, son tres escenarios escasamente estudiados en los que se han puesto en cuestión y desatado conflictos alrededor de la actividad minera y las normativas que la regulan. Precisamente es el objetivo de este proyecto analizar la definición de políticas públicas como momentos de visibilización de posiciones y discursividades en conflicto y entender la formulación de políticas públicas como instancias en que los gobiernos institucionalizan una definición sobre la (des)igualdad. Para ello desplegamos tres ejes de indagación: el análisis del dispositivo de regulación materializado en las decisiones gubernamentales; el esclarecimiento de las disputas entre distintos ámbitos institucionales; y el análisis de las prácticas de resistencia frente a las regulaciones instituidas. Para ello diseñamos una estrategia analítica diferenciada, donde para los primeros dos objetivos se utilizará la recolección documental (normativa) y las entrevistas en profundidad y el análisis de contenido como herramienta de análisis; y el tercer objetivo se ejecuta mediante la recolección de documentos producidos por las organizaciones y las entrevistas en profundidad y el análisis de discurso como técnica de interpretación., Fil: Ciuffolini, María Alejandra. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; Argentina, Fil: Avalle, Gerardo. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; Argentina, Fil: Ibaña, Griselda Beatriz. Universidad Católica de Córdoba. Facultad de Ciencia Política y Relaciones Internacionales; Argentina

Published
2010

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