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In order to prepare the absorbable medical textile material with different degradation rates, two biopolymers of poly L-lactic acid (PLLA) and polycaprolactone (PCL) with different degradation rates, were mixed in different proportions, and made into PLLA/PCL masterbatch. The experiment of degradation in vitro was conducted to reveal the degradation behaviour of PLLA/PCL masterbatch, and the characteristics of masterbatch in degradation, such as surface morphol- ogy, chemical structure, crystallization, mass loss and strength, were analyzed. The results indicated that the surface of PLLA/PCL masterbatch was etched in degradation, and the larger proportion of PCL, the less etching and slower degra- dation. The ester bonds were hydrolyzed firstly, and the crystallization region in PLLA/PCL masterbatch was destroyed gradually to form a non-crystalline region in degradation. The degradation rate of PLLA in composite masterbatch was faster than that of PCL. With increasing of PCL involved in masterbatch, the mass loss rate of masterbatch in degrada- tion decreased. In addition, the more PCL involved in composite masterbatch, the lower breaking strength.

This trial was conducted to investigate the effect of mannose oligosaccharides (MOS) on the growth performance, antioxidation, immunity and disease resistance of Vibro Parahemolyticus in juvenile abalone Haliotis discus hannai Ino. Four formulated diets were produced to contain 0.00 g/kg, 0.40 g/kg, 0.80 g/kg and 1.60 g/kg Actigen®, with functional ingredients of MOS, respectively. Accordingly, the experimental diets were named as A0, A4, A8 and A16. After 120-days feeding trial, the best growth performance was observed in A8 group (P 0.05) and there was no significant difference in A0, A4 and A16 groups. With the increase of dietary MOS, the activity of the total antioxidant capacity in hepatopancreas is increasingly elevated (P 0.05) while no significant difference was observed on activity of glutathione S-transferase (P 0.05). The activities of superoxide dismutase and glutathione peroxidase were firstly increased and then decreased, with the highest values in A8 group (P 0.05). Immune-related parameters were significantly affected by dietary MOS inclusion. Specifically, the activities of alkaline phosphatase and acid phosphatase in hepatopancreas and serum of abalone fed diets containing MOS were significantly higher than those of control A0 group (P 0.05). Moreover, the highest values of both enzymes were observed in hepatopancreas of A8 group but in serum of A16 group, respectively. The lysozyme activities in hepatopancreas and serum of A4 group were significantly higher than those of other groups (P 0.05) and there was no significant difference in A0, A8 and A16 groups (P 0.05). The activities of cytophagy and respiratory burst in serum of abalone were not significantly affected by dietary MOS content (P 0.05). The mRNA levels of focal adhesion kinase and integrin-linked kinase were gradually elevated with the increase of dietary MOS, with the highest value recorded in A16 group (P 0.05). The gene expression of caspse-3 in A8 group was dramatically higher than those of other groups (P 0.05) and there was no significant difference in A0, A4 and A16 groups (P 0.05). The mRNA level of nuclear factor-κB was not significantly affected by dietary MOS (P 0.05). During 56 h of V. Parahemolyticus challenge period, the accumulated mortality rate of abalone fed diets containing MOS were significantly lower than that of control A0 group in each time point (P 0.05). Overall, the lowest rate was happened in A8 group (P 0.05). In conclusion, MOS inclusion in diet has obviously positive effect on growth, immunity and disease resistance capability of abalone, with the optimal level of Actigen® at 0.80 g/kg in diet.

The basalt fibers/poly (lactic acid) composites, as a kind of green environment friendly materials, were prepared by vacuum perfusion method. The effect of silane coupling agent KH550 on the interface of BFs/PLA composites was analyzed. We observed the microstructure of the surface of BFs treated by silane KH550 and the interface of the composites, explored the chemical reaction among silane KH550, BFs and PLA. The silane KH550 succeeded in linking BFs and PLA and enhanced the interfacial bonding strength between BFs and PLA matrix. The crystalline properties of KH550-treated BFs/PLA composites were better than untreated BFs/PLA composites. The mechanical test suggested the silane KH550 had good effect on strengthening BFs/PLA composites.

Drug loaded PLA suture has been one most potential surgery material to help wounds healing. The loaded drug amounts and sustained drug release effect were a vital part for PLA suture. In th...

The drug-release time of suture should meet with the healing time of wound, so it is needed to control the drugrelease performance of polylactic acid (PLA) suture. In this paper, two biodegradable polymers with different degradation rates, such as polycaprolactone (PCL) and polyglycolide (PGA), were applied to carry the drug of tea polyphenol (TP). The drug-loading finishing solution which is made of PCL/PGA carriers and TP, was coated on the PLA suture. The drug-release rate and time of PLA suture could be regulated by adjusting the proportion of PCL/PGA carriers. The results indicate that the surface of drug-loaded PLA suture becomes rough. There is no obvious chemical reaction among the drug, carriers and PLA suture, just physical adhesion. With the increasing of PCL in drug-carriers, the strength of suture gradually increases. At 70/30 of PCL/PGA, the fracture elongation of suture reaches the highest point. In process of degradation, the surface of drugloaded PLA suture appears some holes after 25 weeks. The strength of sutures decreases gradually during degradation, and the effective strength time of sutures with various proportions of PCL/PGA is different. The drug-release rate of the suture is fast at early stage and slow at later stage and the higher the PGA proportion is, the faster the drug-release rate of the suture is.

No studies have been focused on the inclusion of organic selenium in formulated feed of abalone when organic minerals are accepted by aquaculture feed industry. This experiment evaluated the effect of organic selenium on the growth, antioxidation, immunity and gene expressions of selenoproteins in abalone. Graded levels of organic selenium were included to the basal diet at 0.00, 0.15, 0.30 and 0.60 ppm providing 157.83, 322.51, 437.59 and 596.59 ug/kg of selenium in the diet. Accordingly, the diets were named as Se‐0.00, Se‐0.15, Se‐0.30 and Se‐0.60 respectively. Results had shown that survival rate, weight gain rate and shell length increase rate were lowest for Se‐0.60 group (p

Polylactic acid (PLA) surgical sutures are a new type of absorbable sutures that can be degraded and absorbed in the body. However, there is high hydrophobicity for the surface of PLA sutures, which leads to poor biocompatibility and cellular affinity. In order to increase the hydrophilicity, the PLA sutures were etched by lipase firstly, and then grafted with chitosan. The results indicate that the optimal conditions of treating PLA sutures by lipase were as follows: 45℃ reaction temperature, 4.5 g/L concentration of lipase and 8 h reaction time. The sutures were etched by lipase and then formed some grooves and a number of hydroxyl (-OH) bonds, which led to increased surface area and hydrophilicity, but a drop in mass and strength. The optimal conditions of grafting chitosan onto PLA sutures were as follows: 4 h reaction time and 3 g/L concentration of chitosan. The chitosan grafted and loaded on the surface of PLA sutures, and in some areas of the sutures the chitosan reunited, which led to a rough surface and large friction coefficient. Finally, the hydrophilicity of the PLA sutures, treated by lipase and then grafted with chitosan, was greatly improved.

A large number of electronic devices could generate a lot of electromagnetic waves, which could interfere with other equipment and harm the human body. Therefore, an electromagnetic interference shielding (EMI) material is urgently needed to protect the human body and the electronic equipment. In this paper, the multi-wall carbon nanotubes (MWCNTs) and the nano-Fe3O4 were added into the polylactic acid (PLA) matrix to form the composite film with electromagnetic interference shielding performance. And the structure and properties of MWCNTs/Fe3O4/PLA composite films, such as the morphology, chemical structure, crystallization, mechanical property, conductive property, magnetic property and electromagnetic interference shielding property, were researched. The result shows that too much Fe3O4 could lead to agglomeration, and the coupling agent KH570 had grafted and modified the surface of MWCNTs. The MWCNTs and nano-Fe3O4 could increase the crystallinity of PLA matrix. With the increase of MWCNTs, the maximum tensile stress of composite films gradually increased, and the maximum tensile strain decreased, and the resistance value showed a significant downward trend. The Fe3O4 could improve the magnetic properties of composite film. The MWCNTs and Fe3O4 could improve the electromagnetic interference shielding efficiency (EMI SE). The MWCNTs played a more significant role than the Fe3O4 in the process of EMI, and the EMI SE of the composite film with 3:1 ratios of MWCNTs/Fe3O4 could rise to 22 dB.

Polylactic acid (PLA) surgical suture can be absorbed by human body. In order to avoid surgical site infections (SSIs), the drug is usually loaded on the PLA suture, and then the drug can release directly to the wound. Because the different types of wounds heal at different times, it is needed to control the drug release rate of PLA suture to consistent to the wound healing time. Two biopolymers, polyglycolide (PGA) and polycaprolactone (PCL), were selected as the carrier of ciprofloxacin (CPFX) drug, and then the CPFX-PCL/PGA was coated on the PLA suture. The degradation rate of drug-carrier can be controlled by adjusting the proportion of PCL/PGA, which can regulate the rate of CPFX drug release from PLA suture. The results show that the surface of PLA suture, coating with PCL/PGA, was very rough, which led to increased stitching resistance when we were suturing the wound. These materials, such as the PLA suture, the PCL/PGA carriers and the CPFX drug, were just physically mixed rather than chemically reacted, which was very useful for ensuring the original efficacy of CPFX drug. With the increasing of PCL in the carriers, both the breaking strength and elongation of these un-degraded sutures increased. During degradation, the breaking strength of all sutures gradually decreased, and the more PCL in the coating materials, the longer effective strength-time for the suture. With the increasing of PCL in the drug-carrier, the rate of drug releasing became lower. The drug release mechanism of CPFX-PCL/PGA was a synergistic effect of drug diffusion and PCL/PGA carrier dissolution.