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219 results on '"Huang, David Y."'

1. The Effects of Dynamic Learning and the Forgetting Process on an Optimizing Modelling for Full-Service Repair Pricing Contracts for Medical Devices

Author

Jiang, Aiping, Li, Lin, Xu, Xuemin, and Huang, David Y. C.

Subjects
Statistics - Applications
Abstract

In order to improve the profitability and customer service management of original equipment manufacturers (OEMs) in a market where full-service (FS) and on-call service (OS) co-exist, this article extends the optimizing modelling for pricing FS repair contracts with the effects of dynamic learning and forgetting. Along with considering autonomous learning in maintenance practice, this study also analyses how induced learning and forgetting process in a workplace put impact on the pricing optimizing model of FS contracts in the portfolio of FS and OS. A numerical analysis based on real data from a medical industry proves that the enhanced FS pricing model discussed here has two main advantages: (1) It could prominently improve repair efficiency, and (2) It help OEMs gain better profits compared to the original FS model and the sole OS maintenance. Sensitivity analysis shows that if internal failure rate increases, the optimized FS price rises gradually until reaching the maximum value, and profitability to the OEM increases overall; if frequency of induced learning goes up, the optimal FS price rises after a short-term downward trend, with a stable profitability to the OEM.

Published
2022

3. The effects of dynamic learning and the forgetting process on an optimising modelling for full-service repair pricing contracts for medical devices.

Author

Jiang, Aiping, Li, Lin, Xu, Xuemin, and Huang, David Y. C.

Subjects
ORIGINAL equipment manufacturers, PRICES, CUSTOMER service management, VALUE (Economics), NUMERICAL analysis
Abstract

In order to improve the profitability and customer service management of original equipment manufacturers (OEMs) in a market where full-service (FS) and on-call service (OS) co-exist, this article extends the optimising modelling for pricing FS repair contracts with the effects of dynamic learning and forgetting. Along with considering autonomous learning in maintenance practice, this study also analyses how induced learning and forgetting process in a workplace put impact on the pricing optimising model of FS contracts in the portfolio of FS and OS. A numerical analysis based on real data from a medical industry proves that the enhanced FS pricing model discussed here has two main advantages: (1) It could prominently improve repair efficiency, and (2) It help OEMs gain better profits compared to the original FS model and the sole OS maintenance. Sensitivity analysis shows that if internal failure rate increases, the optimised FS price rises gradually until reaching the maximum value, and profitability to the OEM increases overall; if frequency of induced learning goes up, the optimal FS price rises after a short-term downward trend, with a stable profitability to the OEM. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Radon Exposure and Incident Stroke Risk in the Women's Health Initiative

Author

Buchheit, Sophie F., primary, Collins, Jason M., additional, Anthony, Kurtis M., additional, Love, Shelly-Ann M., additional, Stewart, James D., additional, Gondalia, Rahul, additional, Huang, David Y., additional, Manson, JoAnn E., additional, Reiner, Alexander P., additional, Schwartz, Gary G., additional, Vitolins, Mara Z., additional, Schumann, R. Randall, additional, Smith, Richard L., additional, and Whitsel, Eric A., additional

Published
2024
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5. Radon Exposure, Clonal Hematopoiesis, and Stroke Susceptibility in the Women's Health Initiative

Author

Anthony, Kurtis M., primary, Collins, Jason M., additional, Love, Shelly-Ann M., additional, Stewart, James D., additional, Buchheit, Sophie F., additional, Gondalia, Rahul, additional, Schwartz, Gary G., additional, Huang, David Y., additional, Meliker, Jaymie R., additional, Zhang, Zhenzhen, additional, Barac, Ana, additional, Desai, Pinkal, additional, Hayden, Kathleen M., additional, Honigberg, Michael C., additional, Jaiswal, Siddhartha, additional, Natarajan, Pradeep, additional, Bick, Alexander G., additional, Kooperberg, Charles, additional, Manson, JoAnn E., additional, Reiner, Alexander P., additional, and Whitsel, Eric A., additional

Published
2024
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6. Is Obesity Associated with School Dropout? Key Developmental and Ethnic Differences

Author

Lanza, H. Isabella and Huang, David Y. C.

Abstract

Background: We aimed to expand the literature on child obesity and school outcomes by examining associations between obesity and high school dropout, including the role of obesity onset and duration as well as ethnicity. Methods: Data on 5066 children obtained between 1986 and 2010 from the child cohort of the 1979 National Longitudinal Study of Youth (NLSY79) were analyzed. Group-based trajectory analysis identified obesity trajectories from 6 to 18 years. School completion information from age 14 into young adulthood was used to calculate school dropout. Chi-square and pairwise comparison tests were used to identify significant associations between obesity trajectories and school dropout. Results: Adolescents belonging to an increasing trajectory (adolescent-onset obesity) had a higher likelihood of dropping out of high school compared with those belonging to chronic, decreasing (childhood-only obesity), and nonobese trajectories. This association was particularly salient among white adolescents. Conclusions: Obesity onset during early adolescence increased risk of high school dropout. White adolescents were particularly vulnerable. Given that early adolescence is marked by significant biological and social changes, future research should seek to identify the underlying processes linking adolescent obesity and school dropout to decrease school dropout risk among this vulnerable population.

Published
2015
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9. A Latent Class Analysis of Maternal Responsiveness and Autonomy-Granting in Early Adolescence: Prediction to Later Adolescent Sexual Risk-Taking

Author

Lanza, H. Isabella, Huang, David Y. C., Murphy, Debra A., and Hser, Yih-Ing

Abstract

The present study sought to extend empirical inquiry related to the role of parenting on adolescent sexual risk-taking by using latent class analysis (LCA) to identify patterns of adolescent-reported mother responsiveness and autonomy-granting in early adolescence and examine associations with sexual risk-taking in mid- and late-adolescence. Utilizing a sample of 12- to 14-year-old adolescents ("N" = 4,743) from the 1997 National Longitudinal Survey of Youth (NLSY97), results identified a four-class model of maternal responsiveness and autonomy-granting: low responsiveness/high autonomy-granting, moderate responsiveness/moderate autonomy-granting, high responsiveness/low autonomy-granting, high responsiveness/moderate autonomy-granting. Membership in the low responsiveness/high autonomy-granting class predicted greater sexual risk-taking in mid- and late-adolescence compared to all other classes, and membership in the high responsiveness/moderate autonomy-granting class predicted lower sexual risk-taking. Gender and ethnic differences in responsiveness and autonomy-granting class membership were also found, potentially informing gender and ethnic disparities of adolescent sexual risk-taking. (Contains 5 tables.)

Published
2013
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10. Developmental Trajectories of Childhood Obesity and Risk Behaviors in Adolescence

Author

Huang, David Y. C., Lanza, H. Isabella, and Wright-Volel, Kynna

Abstract

Using group-based trajectory modeling, this study examined 5156 adolescents from the child sample of the 1979 National Longitudinal Survey of Youth to identify developmental trajectories of obesity from ages 6-18 and evaluate associations of such trajectories with risk behaviors and psychosocial health in adolescence. Four distinctive obesity trajectories were identified: "Chronically Obese," "Decreasing," "Increasing," and "Non-obese." Males were overrepresented in the Chronically Obese and Increasing groups; females were overrepresented in the Decreasing group. African-Americans were overrepresented in the Chronically Obese, Increasing, and Decreasing groups; in contrast, Whites were overrepresented in the Non-obese group. Obesity trajectories were not associated with greater trends in alcohol use, marijuana use, or delinquency, but Chronically Obese adolescents showed a greater increase in cigarette smoking over time compared to other trajectories. The Increasing trajectory, representing a transition into obesity status from childhood to adolescence, was associated with poorer psychosocial health compared to other trajectories. (Contains 2 figures and 3 tables.)

Published
2013
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11. Developmental Trajectory of Sexual Risk Behaviors from Adolescence to Young Adulthood

Author

Huang, David Y. C., Murphy, Debra A., and Hser, Yih-Ing

Abstract

This study examined the trajectories of sexual risk behaviors among adolescents from ages 15 to 23 and factors associated with those trajectories. The sample was 5,419 adolescents from the 1997 National Longitudinal Survey of Youth. Using group-based trajectory modeling, five distinctive trajectory groups were identified. The High group had a high and increased risk trajectory over the observed ages. The Decreased group had a risk trajectory that accelerated before age 19, but decreased afterwards. The risk trajectories of the Increased-Early and Increased-Late groups were low at age 15 but increased significantly starting at ages 16 and 18 for the groups, respectively. Participants in the Low group remained at low risk over time. Sexual risk behaviors were also positively associated with alcohol use, marijuana use, and delinquency. Results highlight the need for intervention efforts to consider developmental timing of sexual risk behaviors and their associations with other problem behaviors. (Contains 2 tables and 2 figures.)

Published
2012
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12. Parallel Development of Risk Behaviors in Adolescence: Potential Pathways to Co-Occurrence

Author

Huang, David Y. C., Lanza, H. Isabella, Murphy, Debra A., and Hser, Yih-Ing

Abstract

This study used data from 5,382 adolescents from the 1997 United States (US) National Longitudinal Survey of Youth (NLSY97) to investigate developmental pathways of alcohol use, marijuana use, sexual risk behaviors, and delinquency across ages 14 to 20; examine interrelationships among these risk behaviors across adolescence; and evaluate association between risk behavior trajectories and depressive symptoms in adolescence. Group-based dual trajectory modeling, examining trajectories of two outcomes over time, revealed strong interrelationships among developmental trajectories of the four risk behaviors, and indicated potential pathways to co-occurring risk behaviors. Adolescents with higher levels of alcohol use or marijuana use were more likely to engage in higher levels of early sexual risk-taking and delinquency. Moreover, adolescents involved in higher levels of delinquency were at higher risk for engaging in early sexual risk-taking. Also, belonging to the highest risk trajectory of any of the four risk behaviors was positively associated with depressive symptoms in adolescence. (Contains 3 tables and 2 figures.)

Published
2012
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13. Employment Trajectories: Exploring Gender Differences and Impacts of Drug Use

Author

Huang, David Y. C., Evans, Elizabeth, Hara, Motoaki, Weiss, Robert E., and Hser, Yih-Ing

Abstract

This study investigated the impact of drug use on employment over 20 years among men and women, utilizing data on 7661 participants in the National Longitudinal Survey of Youth. Growth mixture modeling was applied, and five distinct employment trajectory groups were identified for both men and women. The identified patterns were largely similar for men and women except that a U-shape employment trajectory was uniquely identified for women. Early-initiation drug users, users of "hard" drugs, and frequent drug users were more likely to demonstrate consistently low levels of employment, and the negative relationship between drug use and employment was more apparent among men than women. Also, positive associations between employment and marriage became more salient for men over time, as did negative associations between employment and childrearing among women. Processes are dynamic and complex, suggesting that throughout the life course, protective factors that reduce the risk of employment problems emerge and change, as do critical periods for maximizing the impact of drug prevention and intervention efforts. (Contains 2 tables and 3 figures.)

Published
2011
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14. Parental Monitoring during Early Adolescence Deters Adolescent Sexual Initiation: Discrete-Time Survival Mixture Analysis

Author

Huang, David Y. C., Murphy, Debra A., and Hser, Yih-Ing

Abstract

We used discrete-time survival mixture modeling to examine 5,305 adolescents from the 1997 National Longitudinal Survey of Youth regarding the impact of parental monitoring during early adolescence (ages 14-16) on initiation of sexual intercourse and problem behavior engagement (ages 14-23). Four distinctive parental-monitoring groups were identified and labeled as "High," "Increasing," "Decreasing," and "Low". About 68% of adolescents received a high level of parental monitoring from ages 14 to 16 (High), 6 and 9% respectively exhibited an accelerated (Increasing) and a decelerated trajectory (Decreasing), and 17% had consistently low parental monitoring (Low). Relative to participants in the Low group, adolescents in the High group delayed sexual initiation by 1.5 years. Males, relative to females, were more likely to have had a low trajectory of parental monitoring, and were more likely to initiate sexual intercourse before age 14. In contrast to White Adolescents, Hispanics and Blacks were less likely to receive High parental monitoring, and had a higher rate of early sexual initiation before age 14. The study demonstrates the temporal relationship of parental monitoring with adolescent sexual initiation from a longitudinal perspective. An increase of parental monitoring across ages is accompanied with a decrease of sexual risk. The continual high level of parental monitoring from ages 14 to 16 also mitigated the risk of engagement in substance use and delinquent behaviors from ages 14 to 23. (Contains 1 table and 3 figures.)

Published
2011
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15. Neurology

Author

Wang, Michael, primary, Aucutt-Walter, Natalie, additional, Jewells, Valerie L., additional, and Huang, David Y., additional

Published
2016
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22. Global Impact of COVID-19 on Stroke Care and Intravenous Thrombolysis

Author

Nogueira, Raul G, Qureshi, Muhammed M, Abdalkader, Mohamad, Martins, Sheila Ouriques, Yamagami, Hiroshi, Qiu, Zhongming, Mansour, Ossama Yassin, Sathya, Anvitha, Czlonkowska, Anna, Tsivgoulis, Georgios, Aguiar de Sousa, Diana, Demeestere, Jelle, Mikulik, Robert, Vanacker, Peter, Siegler, James E, Kõrv, Janika, Biller, Jose, Liang, Conrad W, Sangha, Navdeep S, Zha, Alicia M, Czap, Alexandra L, Holmstedt, Christine Anne, Turan, Tanya N, Ntaios, George, Malhotra, Konark, Tayal, Ashis, Loochtan, Aaron, Ranta, Annamarei, Mistry, Eva A, Alexandrov, Anne W, Huang, David Y, Yaghi, Shadi, Raz, Eytan, Sheth, Sunil A, Mohammaden, Mahmoud H, Frankel, Michael, Bila Lamou, Eric Guemekane, Aref, Hany M, Elbassiouny, Ahmed, Hassan, Farouk, Menecie, Tarek, Mustafa, Wessam, Shokri, Hossam M, Roushdy, Tamer, Sarfo, Fred S, Alabi, Tolulope Oyetunde, Arabambi, Babawale, Nwazor, Ernest O, Sunmonu, Taofiki Ajao, Wahab, Kolawole, Yaria, Joseph, Mohammed, Haytham Hussein, Adebayo, Philip B, Riahi, Anis D, Ben Sassi, Samia, Gwaunza, Lenon, Ngwende, Gift Wilson, Sahakyan, David, Rahman, Aminur, Ai, Zhibing, Bai, Fanghui, Duan, Zhenhui, Hao, Yonggang, Huang, Wenguo, Li, Guangwen, Li, Wei, Liu, Ganzhe, Luo, Jun, Shang, Xianjin, Sui, Yi, Tian, Ling, Wen, Hongbin, Wu, Bo, Yan, Yuying, Yuan, Zhengzhou, Zhang, Hao, Zhang, Jun, Zhao, Wenlong, Zi, Wenjie, Leung, Thomas W, Chugh, Chandril, Huded, Vikram, Menon, Bindu, Pandian, Jeyaraj Durai, Sylaja, P N, Usman, Fritz Sumantri, Farhoudi, Mehdi, Hokmabadi, Elyar Sadeghi, Horev, Anat, Reznik, Anna, Hoffmann, Rotem Sivan, Ohara, Nobuyuki, Sakai, Nobuyuki, Watanabe, Daisuke, Yamamoto, Ryoo, Doijiri, Ryosuke, Tokuda, Naoki, Yamada, Takehiro, Terasaki, Tadashi, Yazawa, Yukako, Uwatoko, Takeshi, Dembo, Tomohisa, Shimizu, Hisao, Sugiura, Yuri, Miyashita, Fumio, Fukuda, Hiroki, Miyake, Kosuke, Shimbo, Junsuke, Sugimura, Yusuke, Yagita, Yoshiki, Takenobu, Yohei, Matsumaru, Yuji, Yamada, Satoshi, Kono, Ryuhei, Kanamaru, Takuya, Yamazaki, Hidekazu, Sakaguchi, Manabu, Todo, Kenichi, Yamamoto, Nobuaki, Sonoda, Kazutaka, Yoshida, Tomoko, Hashimoto, Hiroyuki, Nakahara, Ichiro, Kondybayeva, Aida, Faizullina, Kamila, Kamenova, Saltanat, Zhanuzakov, Murat, Baek, Jang-Hyun, Hwang, Yangha, Lee, Jin Soo, Lee, Si Baek, Moon, Jusun, Park, Hyungjong, Seo, Jung Hwa, Seo, Kwon-Duk, Sohn, Sung Il, Young, Chang Jun, Ahdab, Rechdi, Wan Zaidi, Wan Asyraf, Aziz, Zariah Abdul, Basri, Hamidon Bin, Chung, Law Wan, Ibrahim, Aznita Binti, Ibrahim, Khairul Azmi, Looi, Irene, Tan, Wee Yong, Yahya, Nafisah Wan, Groppa, Stanislav, Leahu, Pavel, Al Hashmi, Amal M, Imam, Yahia Zakaria, Akhtar, Naveed, Pineda-Franks, Maria Carissa, Co, Christian Oliver, Kandyba, Dmitriy, Alhazzani, Adel, Al-Jehani, Hosam, Tham, Carol Huilian, Mamauag, Marlie Jane, Venketasubramanian, Narayanaswamy, Chen, Chih-Hao, Tang, Sung-Chun, Churojana, Anchalee, Akil, Esref, Aykaç, Ozlem, Ozdemir, Atilla Ozcan, Giray, Semih, Hussain, Syed Irteza, John, Seby, Le Vu, Huynh, Tran, Anh Duc, Nguyen, Huy Hoang, Pham, Thong Nhu, Nguyen, Thang Huy, Nguyen, Trung Quoc, Gattringer, Thomas, Enzinger, Christian, Killer-Oberpfalzer, Monika, Bellante, Flavio, De Blauwe, Sofie, Vanhooren, Geert, De Raedt, Sylvie, Dusart, Anne, Lemmens, Robin, Ligot, Noemie, Rutgers, Matthieu Pierre, Yperzeele, Laetitia, Alexiev, Filip, Sakelarova, Teodora, Bedeković, Marina Roje, Budincevic, Hrvoje, Cindrić, Igor, Hucika, Zlatko, Ozretic, David, Saric, Majda Seferovic, Pfeifer, Frantiek, Karpowic, Igor, Cernik, David, Sramek, Martin, Skoda, Miroslav, Hlavacova, Helena, Klecka, Lukas, Koutny, Martin, Vaclavik, Daniel, Skoda, Ondrej, Fiksa, Jan, Hanelova, Katerina, Nevsimalova, Miroslava, Rezek, Robert, Prochazka, Petr, Krejstova, Gabriela, Neumann, Jiri, Vachova, Marta, Brzezanski, Henryk, Hlinovsky, David, Tenora, Dusan, Jura, Rene, Jurák, Lubomír, Novak, Jan, Novak, Ales, Topinka, Zdenek, Fibrich, Petr, Sobolova, Helena, Volny, Ondrej, Christensen, Hanne Krarup, Drenck, Nicolas, Iversen, Helle Klingenberg, Simonsen, Claus Z, Truelsen, Thomas Clement, Wienecke, Troels, Vibo, Riina, Gross-Paju, Katrin, Toomsoo, Toomas, Antsov, Katrin, Caparros, Francois, Cordonnier, Charlotte, Dan, Maria, Faucheux, Jean-Marc, Mechtouff, Laura, Eker, Omer, Lesaine, Emilie, Ondze, Basile, Peres, Roxane, Pico, Fernando, Piotin, Michel, Pop, Raoul, Rouanet, Francois, Gubeladze, Tatuli, Khinikadze, Mirza, Lobjanidze, Nino, Tsikaridze, Alexander, Nagel, Simon, Ringleb, Peter Arthur, Rosenkranz, Michael, Schmidt, Holger, Sedghi, Annahita, Siepmann, Timo, Szabo, Kristina, Thomalla, Götz, Palaiodimou, Lina, Sagris, Dimitrios, Kargiotis, Odysseas, Klivenyi, Peter, Szapary, Laszlo, Tarkanyi, Gabor, Adami, Alessandro, Bandini, Fabio, Calabresi, Paolo, Frisullo, Giovanni, Renieri, Leonardo, Sangalli, Davide, Pirson, Anne V, Uyttenboogaart, Maarten, van den Wijngaard, Ido, Kristoffersen, Espen Saxhaug, Brola, Waldemar, Fudala, Małgorzata, Horoch-Lyszczarek, Ewa, Karlinski, Michal, Kazmierski, Radoslaw, Kram, Pawel, Rogoziewicz, Marcin, Kaczorowski, Rafal, Luchowski, Piotr, Sienkiewicz-Jarosz, Halina, Sobolewski, Piotr, Fryze, Waldemar, Wisniewska, Anna, Wiszniewska, Malgorzata, Ferreira, Patricia, Ferreira, Paulo, Fonseca, Luisa, Marto, João Pedro, Pinho E Melo, Teresa, Nunes, Ana Paiva, Rodrigues, Miguel, Cruz, Vítor Tedim, Falup-Pecurariu, Cristian, Krastev, Georgi, Mako, Miroslav, Alonso de Leciñana, María, Arenillas, Juan F, Ayo-Martin, Oscar, Culebras, Antonio Cruz, Tejedor, Exuperio Diez, Montaner, Joan, Pérez-Sánchez, Soledad, Tola Arribas, Miguel Angel, Vasquez, Alejandro Rodriguez, Mazya, Michael, Bernava, Gianmarco, Brehm, Alex, Machi, Paolo, Fischer, Urs, Gralla, Jan, Michel, Patrik L, Psychogios, Marios-Nikos, Strambo, Davide, Banerjee, Soma, Krishnan, Kailash, Kwan, Joseph, Butt, Asif, Catanese, Luciana, Demchuk, Andrew, Field, Thalia, Haynes, Jennifer, Hill, Michael D, Khosravani, Houman, Mackey, Ariane, Pikula, Aleksandra, Saposnik, Gustavo, Scott, Courtney Anne, Shoamanesh, Ashkan, Shuaib, Ashfaq, Yip, Samuel, Barboza, Miguel A, Barrientos, Jose Domingo, Portillo Rivera, Ligia Ibeth, Gongora-Rivera, Fernando, Novarro-Escudero, Nelson, Blanco, Anmylene, Abraham, Michael, Alsbrook, Diana, Altschul, Dorothea, Alvarado-Ortiz, Anthony J, Bach, Ivo, Badruddin, Aamir, Barazangi, Nobl, Brereton, Charmaine, Castonguay, Alicia, Chaturvedi, Seemant, Chaudhry, Saqib A, Choe, Hana, Choi, Jae H, Dharmadhikari, Sushrut, Desai, Kinjal, Devlin, Thomas G, Doss, Vinodh T, Edgell, Randall, Etherton, Mark, Farooqui, Mudassir, Frei, Don, Gandhi, Dheeraj, Grigoryan, Mikayel, Gupta, Rishi, Hassan, Ameer E, Helenius, Johanna, Kaliaev, Artem, Kaushal, Ritesh, Khandelwal, Priyank, Khawaja, Ayaz M, Khoury, Naim N, Kim, Benny S, Kleindorfer, Dawn O, Koyfman, Feliks, Lee, Vivien H, Leung, Lester Y, Linares, Guillermo, Linfante, Italo, Lutsep, Helmi L, Macdougall, Lisa, Male, Shailesh, Malik, Amer, Masoud, Hesham, McDermott, Molly, Mehta, Brijesh P, Min, Jiangyong, Mittal, Manoj, Morris, Jane G, Multani, Sumeet S, Nahab, Fadi, Nalleballe, Krishna, Nguyen, Claude B, Novakovic-White, Roberta, Ortega-Gutierrez, Santiago, Rahangdale, Rahul H, Ramakrishnan, Pankajavalli, Romero, Jose Rafael, Rost, Natalia, Rothstein, Aaron, Ruland, Sean, Shah, Ruchir, Sharma, Malveeka, Silver, Brian, Simmons, Marc, Singh, Abhishek, Starosciak, Amy K, Strasser, Sheryl L, Szeder, Viktor, Teleb, Mohamed, Tsai, Jenny P, Voetsch, Barbara, Balaguera, Oscar, Pujol Lereis, Virginia A, Luraschi, Adriana, Almeida, Marcele Schettini, Cardoso, Fabricio Buchdid, Conforto, Adriana, De Deus Silva, Leonardo, Giacomini, Luidia Varrone, Lima, Fabricio Oliveira, Longo, Alexandre L, Magalhães, Pedro Sc, Martins, Rodrigo Targa, Mont'alverne, Francisco, Mora Cuervo, Daissy Liliana, Rebello, Leticia Costa, Valler, Lenise, Zetola, Viviane Flumignan, Lavados, Pablo M, Navia, Victor, Olavarría, Verónica V, Almeida Toro, Juan Manuel, Ricardo Amaya, Pablo Felipe, Bayona, Hernan, Corredor-Quintero, Angel Basilio, Rivera Ordonez, Carlos Eduardo, Mantilla Barbosa, Diana Katherine, Lara, Osvaldo, Patiño, Mauricio R, Diaz Escobar, Luis Fernando, Dejesus Melgarejo Farina, Donoband Edson, Villamayor, Analia Cardozo, Zelaya Zarza, Adolfo Javier, Barrientos Iman, Danny Moises, Kadota, Liliana Rodriguez, Campbell, Bruce, Hankey, Graeme J, Hair, Casey, Kleinig, Timothy, Ma, Alice, Martins, Rodrigo Tomazini, Sahathevan, Ramesh, Thijs, Vincent, Salazar, Daniel, Yuan-Hao Wu, Teddy, Haussen, Diogo C, Liebeskind, David, Yavagal, Dileep, Jovin, Tudor G, Zaidat, Osama O, and Nguyen, Thanh N

Subjects
610 Medicine & health
Abstract

OBJECTIVE The objectives of this study were to measure the global impact of the pandemic on the volumes for intravenous thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with two control 4-month periods. METHODS We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified by their ICD-10 codes and/or classifications in stroke databases. RESULTS There were 91,373 stroke admissions in the 4 months immediately before compared to 80,894 admissions during the pandemic months, representing an 11.5% (95%CI, -11.7 to - 11.3, p

Published
2021
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23. Integrin [alpha]v[beta]3 is a coreceptor for human cytomegalovirus

Author

Wang, Xin, Huang, David Y, Huong, Shu-Mei, and Huang, Eng-Shang

Abstract

Human cytomegalovirus (HCMV) is a widespread opportunistic pathogen that causes birth defects in newborns and severe disease in immunocompromised individuals. The broad tropism of HCMV infection suggests that it uses multiple receptors. We recently showed that the epidermal growth factor receptor (EGFR) serves as a receptor for HCMV. Here we show that HCMV also uses integrin [alpha]v[beta]3 as a coreceptor. Upon infection, HCMV glycoproteins gB and gH independently bind to EGFR and [alpha]v[beta]3, respectively, to initiate viral entry and signaling. [alpha]v[beta]3 then translocates to lipid rafts where it interacts with EGFR to induce coordinated signaling. The coordination between EGFR and [alpha]v[beta]3 is essential for the early events of HCMV infection, including viral entry, RhoA downregulation, stress-fiber disassembly and viral nuclear trafficking. Our findings support a model in which EGFR and [alpha]v[beta]3 work together as coreceptors for HCMV entry and signaling. This discovery is fundamental to understanding HCMV pathogenesis and developing treatment strategies targeted to viral receptors., Author(s): Xin Wang [1]; David Y Huang [2]; Shu-Mei Huong [1]; Eng-Shang Huang (corresponding author) [1, 3] HCMV is a [beta]-group herpesvirus that causes severe complications in immunocompromised individuals. HCMV [...]

Published
2005
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26. Contributeurs

Author

Runge, Marschall S., primary, Greganti, M. Andrew, additional, Adimora, Adaora A., additional, Alattar, Maha, additional, Aris, Robert M., additional, Bae-Jump, Victoria Lin, additional, Baggstrom, Maria Q., additional, Barritt, A. Sidney, additional, Bassim, Marc K., additional, Bates, Toby, additional, Beaven, Anne W., additional, Berger, Robert G., additional, Berkowitz, Lee R., additional, Bernard, Stephen A., additional, Blau, William S., additional, Boggess, John F., additional, Bowman, Mary C., additional, Brecher, Mark E., additional, Bromberg, Philip A., additional, Brown, Sue A., additional, Brown, Vickie, additional, Bryson, Paul C., additional, Buckmire, Robert A., additional, Bullitt, Elizabeth, additional, Burkhart, Craig, additional, Busby-Whitehead, M. Janette, additional, Buse, John B., additional, Bynum, Debra L., additional, Carey, Lisa A., additional, Carey, Timothy S., additional, Carson, Culley C., additional, Chang, Patricia P., additional, Chaudhary, Sanjay, additional, Clemmons, David R., additional, Coghill, James M., additional, Colindres, Romulo E., additional, Connolly, AnnaMarie, additional, Copeland, Benjamin J., additional, Correll, Todd, additional, Denu-Ciocca, Cynthia J., additional, Devetski, Thomas S., additional, DeWalt, Darren A., additional, Diaz, Luis A., additional, Donohue, James F., additional, Dooley, Mary Anne, additional, Dostou, Jean M., additional, Drossman, Douglas A., additional, Dupree, Carla Sueta, additional, Eapen, Rose J., additional, Ebert, Charles S., additional, Erdem, Nurum F., additional, Eron, Joseph J., additional, Falk, Ronald J., additional, Farmer-Boatwright, Mary Katherine, additional, Fasy, Elizabeth A., additional, Finkel, Alan G., additional, Finn, William F., additional, Fitzgerald, David P., additional, Ford, Carol A., additional, Forneris, Catherine A., additional, Fowler, Amy M., additional, Fowler, W. Craig, additional, Fowler, Wesley Caswell, additional, Fried, Michael W., additional, Gabriel, Don A., additional, Galvin, Shannon, additional, Gangarosa, Lisa M., additional, Garbutt, James C., additional, Gay, Cynthia, additional, Gaylord, Susan A., additional, Gettes, Leonard S., additional, Ghio, Andrew J., additional, Gilmore, John H., additional, Godley, Paul A., additional, Goldberg, Lee R., additional, Goldberg, Richard M., additional, Goldenberg, Matthew N., additional, Goldstein, Brian P., additional, Greenwood, Robert S., additional, Grimm, Ian S., additional, Grossman, Steven H., additional, Gwyther, Robert E., additional, Haggerty, John J., additional, Harris, Russell P., additional, Heizer, William D., additional, Henderson, Ashley G., additional, Henke, David C., additional, Hill, Michael A., additional, Hinderliter, Alan L., additional, Hinn, Albert R., additional, Hladik, Gerald A., additional, Hoffman, Hal M., additional, Hosseinipour, Mina C., additional, Howard, James F., additional, Huang, David Y., additional, Huang, Xuemei, additional, Hutto, Burton R., additional, Isaacs, Kim L., additional, Israel, Bruce F., additional, Ivester, Thomas S., additional, Jacobe, Heidi T., additional, Jacobson, Peter Lars, additional, Jantac, Lukas, additional, Jawanda, Jaspaul S., additional, Johnson, Sandra M., additional, Jonas, Beth L., additional, Jordan, Joanne M., additional, Juliano, Jonathan J., additional, Kahn, Kevin A., additional, Kaplan, Andrew H., additional, Key, Nigel S., additional, Kim, William Y., additional, Kizer, John S., additional, Klein, Caroline M., additional, Klemmer, Philip J., additional, Kölln, Karen, additional, Koruda, Mark J., additional, Kurz, James E., additional, LaCour, Jeffrey, additional, Ladha, Alim M., additional, Leight, W. Derek, additional, Leone, Peter A., additional, Lindsey, B. Anthony, additional, Madanick, Ryan D., additional, Mandelkehr, Lawrence K., additional, Mann, J. Douglas, additional, Markovic-Plese, Silva, additional, Marshall, Allen F., additional, Mattern, William D., additional, Mayer, Celeste M., additional, Meredith, Travis A., additional, Miller, William C., additional, Mitchell, Beverly S., additional, Moll, Stephan, additional, Morgan, Douglas R., additional, Morrell, Dean S., additional, Muñoz, M. Cristina, additional, Nachman, Patrick H., additional, Nelson, Kelly C., additional, Nester, Carla M., additional, Nicholas, Linda M., additional, Ohman, E. Magnus, additional, O'Neil, Bert H., additional, Ontjes, David A., additional, Orlowski, Robert Z., additional, Parsons, Daniel J., additional, Patel, Dhavalkumar D., additional, Patterson, Cam, additional, Patterson, Kristine B., additional, Peppercorn, Amanda, additional, Pillsbury, Harold C., additional, Rathmell, W. Kimryn, additional, Reuland, Daniel S., additional, Ringel, Yehuda, additional, Rivera, M. Patricia, additional, Rosebrock, Craig N., additional, Rosenberg, Pinchas, additional, Roubey, Robert A.S., additional, Rubenstein, David S., additional, Runge, Susan Riggs, additional, Russo, Mark, additional, Rutala, William A., additional, Sanders, William E., additional, Sanoff, Hanna K., additional, Sanoff, Scott L., additional, Scarlett, Yolanda V., additional, Schwarz, Emily J., additional, Senior, Brent A., additional, Serody, Jonathan S., additional, Shaheen, Nicholas J., additional, Shea, Thomas C., additional, Sheahan, Richard G., additional, Shockley, William W., additional, Shrestha, Roshan, additional, Sickbert-Bennett, Emily E., additional, Sickel, Micah J., additional, Sikich, Linmarie, additional, Simpson, Ross J., additional, Smith, Sidney C., additional, Socinski, Mark A., additional, Sparling, P. Frederick, additional, Stinchcombe, Thomas E., additional, Stouffer, George A., additional, Tarrant, Teresa K., additional, Taylor, Mark, additional, Thomas, Michael J., additional, Thomas, Nancy E., additional, Thorpe, John M., additional, Tilley, Stephen L., additional, Ting, Jenny P., additional, Tomsick, Robert S., additional, van der Horst, Charles M., additional, Vaughn, Bradley V., additional, Vick, Pamela G., additional, Vissers, Robert J., additional, Voorhees, Peter M., additional, Wang, Tracy Y., additional, Watson, Lea C., additional, Weber, David J., additional, Wehbie, Robert S., additional, Weissler, Mark C., additional, Wells, Ellen C., additional, Whang, Young E., additional, Willis, Park W., additional, Winfield, John B., additional, Winzelberg, Gary S., additional, Wohl, David A., additional, Wong, Leslie P., additional, Wu, Diem N., additional, and Zacks, Steven, additional

Published
2011
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29. Neurology

Author

Aucutt-Walter, Natalie, primary, Jewells, Valerie, additional, and Huang, David Y., additional

Published
2010
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30. Contributors

Author

Runge, Marschall S., primary, Greganti, M. Andrew, additional, Adimora, Adaora A., additional, Alattar, Maha, additional, Aris, Robert M., additional, Bae-Jump, Victoria Lin, additional, Baggstrom, Maria Q., additional, Barritt, A. Sidney, additional, Bassim, Marc K., additional, Bates, Toby, additional, Beaven, Anne W., additional, Berger, Robert G., additional, Berkowitz, Lee R., additional, Bernard, Stephen A., additional, Blau, William S., additional, Boggess, John F., additional, Bowman, Mary C., additional, Brecher, Mark E., additional, Bromberg, Philip A., additional, Brown, Sue A., additional, Brown, Vickie, additional, Bryson, Paul C., additional, Buckmire, Robert A., additional, Bullitt, Elizabeth, additional, Burkhart, Craig, additional, Busby-Whitehead, M. Janette, additional, Buse, John B., additional, Bynum, Debra L., additional, Carey, Lisa A., additional, Carey, Timothy S., additional, Carson, Culley C., additional, Chang, Patricia P., additional, Chaudhary, Sanjay, additional, Clemmons, David R., additional, Coghill, James M., additional, Colindres, Romulo E., additional, Connolly, AnnaMarie, additional, Copeland, Benjamin J., additional, Correll, Todd, additional, Denu-Ciocca, Cynthia J., additional, Devetski, Thomas S., additional, DeWalt, Darren A., additional, Diaz, Luis A., additional, Donohue, James F., additional, Dooley, Mary Anne, additional, Dostou, Jean M., additional, Drossman, Douglas A., additional, Dupree, Carla Sueta, additional, Eapen, Rose J., additional, Ebert, Charles S., additional, Erdem, Nurum F., additional, Eron, Joseph J., additional, Falk, Ronald J., additional, Farmer-Boatwright, Mary Katherine, additional, Fasy, Elizabeth A., additional, Finkel, Alan G., additional, Finn, William F., additional, Fitzgerald, David P., additional, Ford, Carol A., additional, Forneris, Catherine A., additional, Fowler, Amy M., additional, Fowler, W. Craig, additional, Fowler, Wesley Caswell, additional, Fried, Michael W., additional, Gabriel, Don A., additional, Galvin, Shannon, additional, Gangarosa, Lisa M., additional, Garbutt, James C., additional, Gay, Cynthia, additional, Gaylord, Susan A., additional, Gettes, Leonard S., additional, Ghio, Andrew J., additional, Gilmore, John H., additional, Godley, Paul A., additional, Goldberg, Lee R., additional, Goldberg, Richard M., additional, Goldenberg, Matthew N., additional, Goldstein, Brian P., additional, Greenwood, Robert S., additional, Grimm, Ian S., additional, Grossman, Steven H., additional, Gwyther, Robert E., additional, Haggerty, John J., additional, Harris, Russell P., additional, Heizer, William D., additional, Henderson, Ashley G., additional, Henke, David C., additional, Hill, Michael A., additional, Hinderliter, Alan L., additional, Hinn, Albert R., additional, Hladik, Gerald A., additional, Hoffman, Hal M., additional, Hosseinipour, Mina C., additional, Howard, James F., additional, Huang, David Y., additional, Huang, Xuemei, additional, Hutto, Burton R., additional, Isaacs, Kim L., additional, Israel, Bruce F., additional, Ivester, Thomas S., additional, Jacobe, Heidi T., additional, Jacobson, Peter Lars, additional, Jantac, Lukas, additional, Jawanda, Jaspaul S., additional, Johnson, Sandra M., additional, Jonas, Beth L., additional, Jordan, Joanne M., additional, Juliano, Jonathan J., additional, Kahn, Kevin A., additional, Kaplan, Andrew H., additional, Key, Nigel S., additional, Kim, William Y., additional, Kizer, John S., additional, Klein, Caroline M., additional, Klemmer, Philip J., additional, Kölln, Karen, additional, Koruda, Mark J., additional, Kurz, James E., additional, LaCour, Jeffrey, additional, Ladha, Alim M., additional, Leight, W. Derek, additional, Leone, Peter A., additional, Lindsey, B. Anthony, additional, Madanick, Ryan D., additional, Mandelkehr, Lawrence K., additional, Mann, J. Douglas, additional, Markovic-Plese, Silva, additional, Marshall, Allen F., additional, Mattern, William D., additional, Mayer, Celeste M., additional, Meredith, Travis A., additional, Miller, William C., additional, Mitchell, Beverly S., additional, Moll, Stephan, additional, Morgan, Douglas R., additional, Morrell, Dean S., additional, Muñoz, M. Cristina, additional, Nachman, Patrick H., additional, Nelson, Kelly C., additional, Nester, Carla M., additional, Nicholas, Linda M., additional, Ohman, E. Magnus, additional, O'Neil, Bert H., additional, Ontjes, David A., additional, Orlowski, Robert Z., additional, Parsons, Daniel J., additional, Patel, Dhavalkumar D., additional, Patterson, Cam, additional, Patterson, Kristine B., additional, Peppercorn, Amanda, additional, Pillsbury, Harold C., additional, Rathmell, W. Kimryn, additional, Reuland, Daniel S., additional, Ringel, Yehuda, additional, Rivera, M. Patricia, additional, Rosebrock, Craig N., additional, Rosenberg, Pinchas, additional, Roubey, Robert A.S., additional, Rubenstein, David S., additional, Runge, Susan Riggs, additional, Russo, Mark, additional, Rutala, William A., additional, Sanders, William E., additional, Sanoff, Hanna K., additional, Sanoff, Scott L., additional, Scarlett, Yolanda V., additional, Schwarz, Emily J., additional, Senior, Brent A., additional, Serody, Jonathan S., additional, Shaheen, Nicholas J., additional, Shea, Thomas C., additional, Sheahan, Richard G., additional, Shockley, William W., additional, Shrestha, Roshan, additional, Sickbert-Bennett, Emily E., additional, Sickel, Micah J., additional, Sikich, Linmarie, additional, Simpson, Ross J., additional, Smith, Sidney C., additional, Socinski, Mark A., additional, Sparling, P. Frederick, additional, Stinchcombe, Thomas E., additional, Stouffer, George A., additional, Tarrant, Teresa K., additional, Taylor, Mark, additional, Thomas, Michael J., additional, Thomas, Nancy E., additional, Thorpe, John M., additional, Tilley, Stephen L., additional, Ting, Jenny P., additional, Tomsick, Robert S., additional, van der Horst, Charles M., additional, Vaughn, Bradley V., additional, Vick, Pamela G., additional, Vissers, Robert J., additional, Voorhees, Peter M., additional, Wang, Tracy Y., additional, Watson, Lea C., additional, Weber, David J., additional, Wehbie, Robert S., additional, Weissler, Mark C., additional, Wells, Ellen C., additional, Whang, Young E., additional, Willis, Park W., additional, Winfield, John B., additional, Winzelberg, Gary S., additional, Wohl, David A., additional, Wong, Leslie P., additional, Wu, Diem N., additional, and Zacks, Steven, additional

Published
2009
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33. Contrast sensitivity visual acuity in REM sleep behavior disorder: a comparison with and without Parkinson disease

Author

Whitfield, Whitney H., primary, Barr, Garrett Q., additional, Khayata, Matthew J., additional, Vogt, Peggy H., additional, Keasler, Eric M., additional, Sanchez, Jacqueline M., additional, Song, Ziyan, additional, Dieujuste, Marvin, additional, Cardon, Brandon, additional, Riggs, Ryan, additional, Pique, Karina N., additional, Merin, Elliot, additional, Huang, David Y., additional, and Maitland, Charles G., additional

Published
2020
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34. Stem Cells as an Emerging Paradigm in Stroke 4: Advancing and Accelerating Preclinical Research

Author

Boltze, Johannes, Modo, Michel M., Mays, Robert W., Taguchi, Akihiko, Jolkkonen, Jukka, Savitz, Sean I., Bates, Damien, Bath, Philip, Carmichael, Stanley Thomas, Cox, Charles S., Daadi, Marcel M., Tejedor, Euperio Diez, Grande, Andrew W., Gutiérrez-Fernández, María, Hematti, Peiman, Hess, David, Huang, David Y., Kokaia, Zaal, Kuroda, Satoshi, Moniche, Francisco P., Muir, Keith, Olson, Scott, de Castro, Paulo Henrique Rosado, Sinden, John, Satani, Nikunj, Shichinohe, Hideo, Steinberg, Gary K., Walczak, Piotr, Wechsler, Lawrence, West, Franklin, Vahidy, Farhaan, Vawter, Dorothy E., Yavagal, Dileep R., Yang, Bing, Zrinzo, Ludvic, and The STEPS 4 Participants

Subjects
Oncology, medicine.medical_specialty, RM, Biomedical Research, MEDLINE, Ischemia, Brain Ischemia, Translational Research, Biomedical, Preclinical research, Internal medicine, Medicine, Animals, Humans, Stroke, Advanced and Specialized Nursing, business.industry, QH, Stem Cells, medicine.disease, Disease Models, Animal, Neurology (clinical), Stem cell, Cardiology and Cardiovascular Medicine, business, RB, RC
Published
2019

35. Delineation of Human Carotid Plaque Features In Vivo by Exploiting Displacement Variance

Author

Torres, Gabriela, Czernuszewicz, Tomasz J., Homeister, Jonathon W., Caughey, Melissa C., Huang, Benjamin Y., Lee, Ellie R., Zamora, Carlos A., Farber, Mark A., Marston, William A., Huang, David Y., Nichols, Timothy C., and Gallippi, Caterina M.

Subjects
Male, Endarterectomy, Carotid, Middle Aged, Signal-To-Noise Ratio, equipment and supplies, Article, Plaque, Atherosclerotic, Carotid Arteries, Image Interpretation, Computer-Assisted, Elasticity Imaging Techniques, Humans, Carotid Stenosis, Female, Aged
Abstract

While in vivo acoustic radiation force impulse (ARFI)-induced peak displacement (PD) has been demonstrated to have high sensitivity and specificity for differentiating soft from stiff plaque components in patients with carotid plaque, the parameter exhibits poorer performance for distinguishing between plaque features with similar stiffness. To improve discrimination of carotid plaque features relative to PD, we hypothesize that signal correlation and signal-to-noise ratio (SNR) can be combined, outright or via displacement variance. Plaque feature detection by displacement variance, evaluated as the decadic logarithm of the variance of acceleration and termed "log(VoA)," was compared to that achieved by exploiting SNR, cross correlation coefficient, and ARFI-induced PD outcome metrics. Parametric images were rendered for 25 patients undergoing carotid endarterectomy, with spatially matched histology confirming plaque composition and structure. On average, across all plaques, log(VoA) was the only outcome metric with values that statistically differed between regions of lipid-rich necrotic core (LRNC), intraplaque hemorrhage (IPH), collagen (COL), and calcium (CAL). Further, log(VoA) achieved the highest contrast-to-noise ratio (CNR) for discriminating between LRNC and IPH, COL and CAL, and grouped soft (LRNC and IPH) and stiff (COL and CAL) plaque components. More specifically, relative to the previously demonstrated ARFI PD parameter, log(VoA) achieved 73% higher CNR between LRNC and IPH and 59% higher CNR between COL and CAL. These results suggest that log(VoA) enhances the differentiation of LRNC, IPH, COL, and CAL in human carotid plaques, in vivo, which is clinically relevant to improving stroke risk prediction and medical management.

Published
2019

37. Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

Author

Strittmatter, Warren J., Weisgraber, Karl H., Huang, David Y., Li-Ming Dong, Salvesen, Guy S., Pericak-Vance, Margaret, Schmechel, Donald, Saunders, Ann M., Goldgaber, Dmitry, and Roses, Allen D.

Subjects
Apolipoproteins -- Analysis, Peptides -- Research, Alzheimer's disease -- Causes of, Science and technology
Abstract

The binding of synthetic amyloid beta (beta/A4) peptide was compared to purified apolipoprotein E4 (apoE4) and the most common isoform, apoE3, to find if apoE4 is related to enhanced vulnerability to Alzheimer disease. The two isoforms form a complex with the beta/A4 peptide in different ways. ApoE is regionalized in the senile plaques, congophilic angiopathy and neurofibrillary tangles of Alzheimer disease.

Published
1993

38. Delineation of Human Carotid Plaque Features In Vivo by Exploiting Displacement Variance

Author

Torres, Gabriela, primary, Czernuszewicz, Tomasz J., additional, Homeister, Jonathon W., additional, Caughey, Melissa C., additional, Huang, Benjamin Y., additional, Lee, Ellie R., additional, Zamora, Carlos A., additional, Farber, Mark A., additional, Marston, William A., additional, Huang, David Y., additional, Nichols, Timothy C., additional, and Gallippi, Caterina M., additional

Published
2019
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43. Strategies for improving outcomes in the acute management of ischemic stroke in rural emergency departments: a quality improvement initiative in the Stroke Belt

Author

Jauch,Edward C, Huang,David Y, Gardner,Allison J, Blum,Julie L, Jauch,Edward C, Huang,David Y, Gardner,Allison J, and Blum,Julie L

Abstract

Edward C Jauch,1 David Y Huang,2 Allison J Gardner,3 Julie L Blum3 1Department of Emergency Medicine, Medical University of South Carolina, Charleston, SC, USA; 2Department of Neurology, Division of Stroke and Vascular Neurology, University of North Carolina School of Medicine, Chapel Hill, NC, USA; 3QI Institute, Med-IQ, Baltimore, MD, USA Background: The timely evaluation and initiation of treatment for acute ischemic stroke (AIS) is critical to optimal patient outcomes. However, clinical practice often falls short of guideline-established goals. Hospitals in rural regions of the USA, and notably those in the Stroke Belt, are particularly challenged to meet timing goals since the vast majority of primary stroke centers (PSCs) are concentrated in urban academic institutions. Methods: Between May 2015 and May 2017, emergency department (ED) teams from 5 non-PSC hospitals in the Stroke Belt participated in a quality improvement (QI) initiative. The intervention included a baseline practice assessment survey, repeat audit-and-feedback cycles with patient data on AIS treatment timing, personalized Continuing Medical Education/Continuing Education-certified grand rounds sessions at each participating site with expert study faculty, targeted reinforcement of best practices, and follow-up to evaluate the benefits and limitations of the intervention. Results: At the start of the initiative, clinical staff from participating EDs overestimated the proportion of patients with AIS who received alteplase within the guideline-recommended 60-minute door-to-needle window at their facility. At the end of the 6-month intervention period, significantly more patients were treated with alteplase within 60 minutes of ED arrival compared to baseline across the entire sample (1.9% of patients at baseline vs. 5.2% at 6 months; P < 0.01). Similarly, there was a trend toward a decrease in the percentage of patients whose alteplase treatment was initiated more than 60 minutes after the

Published
2018

44. Global Impact of COVID-19 on Stroke Care and IV Thrombolysis

Author

Nogueira, Raul G., Qureshi, Muhammad M., Abdalkader, Mohamad, Martins, Sheila Ouriques, Yamagami, Hiroshi, Qiu, Zhongming, Mansour, Ossama Yassin, Sathya, Anvitha, Czlonkowska, Anna, Tsivgoulis, Georgios, Aguiar de Sousa, Diana, Demeestere, Jelle, Mikulik, Robert, Vanacker, Peter, Siegler, James E., Kõrv, Janika, Biller, Jose, Liang, Conrad W., Sangha, Navdeep S., Zha, Alicia M., Czap, Alexandra L., Holmstedt, Christine Anne, Turan, Tanya N., Ntaios, George, Malhotra, Konark, Tayal, Ashis, Loochtan, Aaron, Ranta, Annamarei, Mistry, Eva A., Alexandrov, Anne W., Huang, David Y., Yaghi, Shadi, Raz, Eytan, Sheth, Sunil A., Mohammaden, Mahmoud H., Frankel, Michael, Bila Lamou, Eric Guemekane, Aref, Hany M., Elbassiouny, Ahmed, Hassan, Farouk, Menecie, Tarek, Mustafa, Wessam, Shokri, Hossam M., Roushdy, Tamer, Sarfo, Fred S., Alabi, Tolulope Oyetunde, Arabambi, Babawale, Nwazor, Ernest O., Sunmonu, Taofiki Ajao, Wahab, Kolawole, Yaria, Joseph, Mohammed, Haytham Hussein, Adebayo, Philip B., Riahi, Anis D., Sassi, Samia Ben, Gwaunza, Lenon, Ngwende, Gift Wilson, Sahakyan, David, Rahman, Aminur, Ai, Zhibing, Bai, Fanghui, Duan, Zhenhui, Hao, Yonggang, Huang, Wenguo, Li, Guangwen, Li, Wei, Liu, Ganzhe, Luo, Jun, Shang, Xianjin, Sui, Yi, Tian, Ling, Wen, Hongbin, Wu, Bo, Yan, Yuying, Yuan, Zhengzhou, Zhang, Hao, Zhang, Jun, Zhao, Wenlong, Zi, Wenjie, Leung, Thomas W., Chugh, Chandril, Huded, Vikram, Menon, Bindu, Pandian, Jeyaraj Durai, Sylaja, PN, Usman, Fritz Sumantri, Farhoudi, Mehdi, Hokmabadi, Elyar Sadeghi, Horev, Anat, Reznik, Anna, Sivan Hoffmann, Rotem, Ohara, Nobuyuki, Sakai, Nobuyuki, Watanabe, Daisuke, Yamamoto, Ryoo, Doijiri, Ryosuke, Tokuda, Naoki, Yamada, Takehiro, Terasaki, Tadashi, Yazawa, Yukako, Uwatoko, Takeshi, Dembo, Tomohisa, Shimizu, Hisao, Sugiura, Yuri, Miyashita, Fumio, Fukuda, Hiroki, Miyake, Kosuke, Shimbo, Junsuke, Sugimura, Yusuke, Yagita, Yoshiki, Takenobu, Yohei, Matsumaru, Yuji, Yamada, Satoshi, Kono, Ryuhei, Kanamaru, Takuya, Yamazaki, Hidekazu, Sakaguchi, Manabu, Todo, Kenichi, Yamamoto, Nobuaki, Sonoda, Kazutaka, Yoshida, Tomoko, Hashimoto, Hiroyuki, Nakahara, Ichiro, Kondybayeva, Aida, Faizullina, Kamila, Kamenova, Saltanat, Zhanuzakov, Murat, Baek, Jang-Hyun, Hwang, Yangha, Lee, Jin Soo, Lee, Si Baek, Moon, Jusun, Park, Hyungjong, Seo, Jung Hwa, Seo, Kwon-Duk, Sohn, Sung Il, Young, Chang Jun, Ahdab, Rechdi, Wan Zaidi, Wan Asyraf, Aziz, Zariah Abdul, Basri, Hamidon bin, Chung, Law Wan, Ibrahim, Aznita Binti, Ibrahim, Khairul Azmi, Looi, Irene, Tan, Wee Yong, Yahya, Nafisah Wan, Groppa, Stanislav, Leahu, Pavel, Al Hashmi, Amal M., Imam, Yahia Zakaria, Akhtar, Naveed, Pineda-Franks, Maria Carissa, Co, Christian Oliver, Kandyba, Dmitriy, Alhazzani, Adel, Al-Jehani, Hosam, Tham, Carol Huilian, Mamauag, Marlie Jane, Venketasubramanian, Narayanaswamy, Chen, Chih-Hao, Tang, Sung-Chun, Churojana, Anchalee, Akil, Esref, aykaç, özlem, Ozdemir, Atilla Ozcan, Giray, Semih, Hussain, Syed Irteza, John, Seby, Le Vu, Huynh, Tran, Anh Duc, Nguyen, Huy Hoang, Nhu Pham, Thong, Nguyen, Thang Huy, Nguyen, Trung Quoc, Gattringer, Thomas, Enzinger, Christian, Killer-Oberpfalzer, Monika, Bellante, Flavio, De Blauwe, Sofie, Vanhooren, Geert, De Raedt, Sylvie, Dusart, Anne, Lemmens, Robin, Ligot, Noemie, Pierre Rutgers, Matthieu, Yperzeele, Laetitia, Alexiev, Filip, Sakelarova, Teodora, Bedeković, Marina Roje, Budincevic, Hrvoje, Cindric, Igor, Hucika, Zlatko, Ozretic, David, Saric, Majda Seferovic, Pfeifer, František, Karpowic, Igor, Cernik, David, Sramek, Martin, Skoda, Miroslav, Hlavacova, Helena, Klecka, Lukas, Koutny, Martin, Vaclavik, Daniel, Skoda, Ondrej, Fiksa, Jan, Hanelova, Katerina, Nevsimalova, Miroslava, Rezek, Robert, Prochazka, Petr, Krejstova, Gabriela, Neumann, Jiri, Vachova, Marta, Brzezanski, Henryk, Hlinovsky, David, Tenora, Dusan, Jura, Rene, Jurák, Lubomír, Novak, Jan, Novak, Ales, Topinka, Zdenek, Fibrich, Petr, Sobolova, Helena, Volny, Ondrej, Krarup Christensen, Hanne, Drenck, Nicolas, Klingenberg Iversen, Helle, Simonsen, Claus Z., Truelsen, Thomas Clement, Wienecke, Troels, Vibo, Riina, Gross-Paju, Katrin, Toomsoo, Toomas, Antsov, Katrin, Caparros, Francois, Cordonnier, Charlotte, Dan, Maria, Faucheux, Jean-Marc, Mechtouff, Laura, Eker, Omer, Lesaine, Emilie, Ondze, Basile, Peres, Roxane, Pico, Fernando, Piotin, Michel, Pop, Raoul, Rouanet, Francois, Gubeladze, Tatuli, Khinikadze, Mirza, Lobjanidze, Nino, Tsiskaridze, Alexander, Nagel, Simon, Ringleb, Peter Arthur, Rosenkranz, Michael, Schmidt, Holger, Sedghi, Annahita, Siepmann, Timo, Szabo, Kristina, Thomalla, Götz, Palaiodimou, Lina, Sagris, Dimitrios, Kargiotis, Odysseas, Klivenyi, Peter, Szapary, Laszlo, Tarkanyi, Gabor, Adami, Alessandro, Bandini, Fabio, Calabresi, Paolo, Frisullo, Giovanni, Renieri, Leonardo, Sangalli, Davide, Pirson, Anne, Uyttenboogaart, Maarten, van den Wijngaard, Ido, Kristoffersen, Espen Saxhaug, Brola, Waldemar, Fudala, Małgorzata, Horoch-Lyszczarek, Ewa, Karlinski, Michal, Kazmierski, Radoslaw, Kram, Pawel, Rogoziewicz, Marcin, Kaczorowski, Rafal, Luchowski, Piotr, Sienkiewicz-Jarosz, Halina, Sobolewski, Piotr, Fryze, Waldemar, Wisniewska, Anna, Wiszniewska, Malgorzata, Ferreira, Patricia, Ferreira, Paulo, Fonseca, Luisa, Marto, João Pedro, Pinho e Melo, Teresa, Nunes, Ana Paiva, Rodrigues, Miguel, Tedim Cruz, Vítor, Falup-Pecurariu, Cristian, Krastev, Georgi, Mako, Miroslav, de Leciñana, María Alonso, Arenillas, Juan F., Ayo-Martin, Oscar, Cruz Culebras, Antonio, Tejedor, Exuperio Diez, Montaner, Joan, Pérez-Sánchez, Soledad, Tola Arribas, Miguel Angel, Rodriguez Vasquez, Alejandro, Mayza, Michael, Bernava, Gianmarco, Brehm, Alex, Machi, Paolo, Fischer, Urs, Gralla, Jan, Michel, Patrik L., Psychogios, Marios-Nikos, Strambo, Davide, Banerjee, Soma, Krishnan, Kailash, Kwan, Joseph, Butt, Asif, Catanese, Luciana, Demchuk, Andrew M., Field, Thalia, Haynes, Jennifer, Hill, Michael D., Khosravani, Houman, Mackey, Ariane, Pikula, Aleksandra, Saposnik, Gustavo, Scott, Courtney Anne, Shoamanesh, Ashkan, Shuaib, Ashfaq, Yip, Samuel, Barboza, Miguel A., Barrientos, Jose Domingo, Portillo Rivera, Ligia Ibeth, Gongora-Rivera, Fernando, Novarro-Escudero, Nelson, Blanco, Anmylene, Abraham, Michael, Alsbrook, Diana, Altschul, Dorothea, Alvarado-Ortiz, Anthony J., Bach, Ivo, Badruddin, Aamir, Barazangi, Nobl, Brereton, Charmaine, Castonguay, Alicia, Chaturvedi, Seemant, Chaudry, Saqib A., Choe, Hana, Choi, Jae H., Dharmadhikari, Sushrut, Desai, Kinjal, Devlin, Thomas G., Doss, Vinodh T., Edgell, Randall, Etherton, Mark, Farooqui, Mudassir, Frei, Don, Gandhi, Dheeraj, Grigoryan, Mikayel, Gupta, Rishi, Hassan, Ameer E., Helenius, Johanna, Kaliaev, Artem, Kaushal, Ritesh, Khandelwal, Priyank, Khawaja, Ayaz M., Khoury, Naim N., Kim, Benny S., Kleindorfer, Dawn O., Koyfman, Feliks, Lee, Vivien H., Leung, Lester Y., Linares, Guillermo, Linfante, Italo, Lutsep, Helmi L., Macdougall, Lisa, Male, Shailesh, Malik, Amer M., Masoud, Hesham, McDermott, Molly, Mehta, Brijesh P., Min, Jiangyong, Mittal, Manoj, Morris, Jane G., Multani, Sumeet S., Nahab, Fadi, Nalleballe, Krishna, Nguyen, Claude B., Novakovic-White, Roberta, Ortega-Gutierrez, Santiago, Rahangdale, Rahul H., Ramakrishnan, Pankajavalli, Romero, Jose Rafael, Rost, Natalia, Rothstein, Aaron, Ruland, Sean, Shah, Ruchir, Sharma, Malveeka, Silver, Brian, Simmons, Marc, Singh, Abhishek, Starosciak, Amy K., Strasser, Sheryl L., Szeder, Viktor, Teleb, Mohamed, Tsai, Jenny P., Voetsch, Barbara, Balaguera, Oscar, Pujol Lereis, Virginia A., Luraschi, Adriana, Almeida, Marcele Schettini, Cardoso, Fabricio Buchdid, Conforto, Adriana, De Deus Silva, Leonardo, Varrone Giacomini, Luidia, Oliveira Lima, Fabricio, Longo, Alexandre L., Magalhães, Pedro S.C., Martins, Rodrigo Targa, Mont'alverne, Francisco, Mora Cuervo, Daissy Liliana, Costa Rebello, Leticia, Valler, Lenise, Zetola, Viviane Flumignan, Lavados, Pablo M., Navia, Victor, Olavarría, Verónica V., Almeida Toro, Juan Manuel, Amaya, Pablo Felipe Ricardo, Bayona, Hernan, Corredor, Angel, Rivera Ordonez, Carlos Eduardo, Mantilla Barbosa, Diana Katherine, Lara, Osvaldo, Patiño, Mauricio R., Diaz Escobar, Luis Fernando, Dejesus Melgarejo Farina, Donoband Edson, Cardozo Villamayor, Analia, Zelaya Zarza, Adolfo Javier, Barrientos Iman, Danny Moises, Rodriguez Kadota, Liliana, Campbell, Bruce, Hankey, Graeme J., Hair, Casey, Kleinig, Timothy, Ma, Alice, Tomazini Martins, Rodrigo, Sahathevan, Ramesh, Thijs, Vincent, Salazar, Daniel, Yuan-Hao Wu, Teddy, Haussen, Diogo C., Liebeskind, David, Yavagal, Dileep R., Jovin, Tudor G., Zaidat, Osama O., and Nguyen, Thanh N.

Published
2021
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45. Abstract 67: RNA Expression Differentiates Large Artery And Cardioembolic Stroke: A Pilot Analysis From The BASE Trial

Author

Jauch, Edward C, primary, Barreto, Andrew D, additional, Broderick, Joseph P, additional, Char, Doug M, additional, Cucchiara, Brett L, additional, Hicks, William J, additional, Jickling, Glen C, additional, June, Jeffrey G, additional, Liebeskind, David S, additional, Miller, Joseph B, additional, Morgan, Judy, additional, O’Neill, John, additional, Schoonover, Tim, additional, Sharp, Frank, additional, Peacock, W. F, additional, Lowenkopf, Ted J, additional, and Huang, David Y, additional

Published
2018
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