238 results on '"Hiroki Inagaki"'
Search Results
2. Sex-specific factors associated with acceptance of smartwatches among urban older adults: the Itabashi longitudinal study on aging
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Naoki Deguchi, Yosuke Osuka, Narumi Kojima, Keiko Motokawa, Masanori Iwasaki, Hiroki Inagaki, Fumiko Miyamae, Tsuyoshi Okamura, Hirohiko Hirano, Shuichi Awata, and Hiroyuki Sasai
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wearable healthcare device ,mobile health ,smart wearables ,health promotion ,technology innovativeness ,Public aspects of medicine ,RA1-1270 - Abstract
Smartwatches (SW) are wearable devices that support daily life and monitor an individual’s health and activity status. This information is utilized to promote behavior modification, which could help prevent chronic diseases and manage the health of older adults. Despite being interested in SWs, older adults tend to decrease their SW usage as they age. Therefore, understanding the acceptance of SWs among older individuals can facilitate individual health management through digital health technology. This study investigated the factors associated with the acceptance of SWs among older adults in Japan and the variations in the factors by sex. This study utilized data from the 2022 Itabashi Longitudinal Study on Aging, an ongoing cohort study conducted by the Tokyo Metropolitan Institute for Geriatrics and Gerontology. We included 899 eligible individuals aged ≥65 years. Participants were classified into three groups: possessing SW (possessor group), not possessing SW but interested in possession in the future (interest group), and not interested in possession in the future (non-interest group) using a self-administered questionnaire. The level of SW acceptance was operationally defined as follows: low (non-interest group), medium (interest group), and high (possessor group). Further, we evaluated the association of acceptance and purchase intentions of SWs with sociodemographic variables, technology literacy, and health variables. Among the participants, 4.2% possessed SWs, with no significant sex difference (men, 4.2%; women, 4.3%). Among men, age
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- 2024
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3. Sliding velocity dependence of kinetic friction coefficient of bronze-filled polytetrafluoroethylene and its application to robustness improvement of friction damper
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Satoru MAEGAWA, Hiroki INAGAKI, Xiaoxu LIU, and Fumihiro ITOIGAWA
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friction damper ,vibration control ,velocity dependence of friction coefficient ,Mechanical engineering and machinery ,TJ1-1570 - Abstract
This study demonstrates that the robustness of friction dampers can be enhanced by using the positive velocity dependence of the kinetic friction force. First, we show that the kinetic friction coefficient can be reduced under extremely low sliding velocity conditions by using oleyl acid phosphate (OLAP) as an additive to the lubricant on the sliding surfaces between bronze-filled polytetrafluoroethylene (PTFE) and steel. Next, based on the results of the numerical simulations, we show that the use of a sliding surface with a positive velocity dependence of the friction coefficient is effective in improving the vibration reduction ability of the friction dampers. Finally, our findings are demonstrated through a simplified experiment.
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- 2023
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4. Early- to late-life environmental factors and late-life global cognition in septuagenarian and octogenarians: The SONIC study
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Yoshiko Lily Ishioka, Yukie Masui, Takeshi Nakagawa, Madoka Ogawa, Hiroki Inagaki, Saori Yasumoto, Kazunori Ikebe, Kei Kamide, Yasumichi Arai, Tatsuro Ishizaki, and Yasuyuki Gondo
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2800 Developmental Psychology ,2860 Gerontology ,Psychology ,BF1-990 - Abstract
This study aimed to evaluate cognitively stimulating environments throughout life and to examine direct and indirect associations between these environments and late-life cognition. Early-life education, three domains of work complexity (data, people, and things) based on the longest-held occupation, and engagement in late-life leisure activities (LAs) were assessed. A structural equation model was developed using cross-sectional data of 1721 Japanese older adults in 70 ± 1 and 80 ± 1 years. The model confirmed significant direct effects of work complexity with data and late-life LAs on late-life cognitive performance. The associations of education and work complexity with late-life cognition were mediated through the subsequent environment(s). However, the total effects of work complexity with people and things on late-life cognition were insignificant. The findings suggest that cognitively stimulating activities in adulthood and beyond may lead to individual differences in late-life global cognition. In addition, antecedent complex environments might make subsequent life environments more cognitively stimulating. The results are discussed from the perspectives of cognitive plasticity and environmental complexity.
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- 2023
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5. Promoting cultural change towards dementia friendly communities: a multi-level intervention in Japan
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Shuji Tsuda, Hiroki Inagaki, Tsuyoshi Okamura, Mika Sugiyama, Madoka Ogawa, Fumiko Miyamae, Ayako Edahiro, Chiaki Ura, Naoko Sakuma, and Shuichi Awata
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Dementia-friendly community ,Dementia ,Social capital ,Social networks ,Japan ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background Effective strategies to develop dementia-friendly communities (DFCs) are needed in aging societies. We aimed to propose a strategy to develop DFCs from a Japanese perspective and to evaluate an intervention program that adopted the strategy. Methods This study implemented a multi-level intervention that emphasized nurturing community social capital in a large apartment complex in the Tokyo metropolitan area in 2017. We offered an inclusive café that was open for extended hours as a place to socialize and a center for activities that included monthly public lectures. Individual consultation on daily life issues was also available for free at the café. Postal surveys were sent out to all older residents aged 70 years and older in 2016 and 2019. With a one-group pre-test and post-test design, we assessed changes in the proportion of older residents who had social interaction with friends and those who were confident about living in the community, even if they were living with dementia. Results Totals of 2633 and 2696 residents completed the pre and post-intervention surveys, respectively. The mean age of the pre-intervention respondents was 77.4 years; 45.7% lived alone and 7.7% reported living with impaired cognitive function. The proportion of men who had regular social interaction and were confident about living in their community with dementia increased significantly from 38.8 to 44.5% (p = 0.0080) and from 34.1 to 38.3% (p = 0.045), respectively. Similar significant increases were observed in the subgroup of men living with impaired cognitive function, but not in the same subgroup for women. Conclusions The intervention benefitted male residents who were less likely to be involved in the community’s web of social networks at baseline. A strategy to create DFCs that emphasizes nurturing community social capital can form a foundation for DFCs. Trial registration This study was retrospectively registered in the University hospital Medical Information Network (UMIN) Clinical Trial Registry (registry number: UMIN000038193 , date of registration: Oct 3, 2019).
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- 2022
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6. Association of personality traits with polypharmacy among community-dwelling older adults in Japan: a cross-sectional analysis of data from the SONIC study
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Yuko Yoshida, Tatsuro Ishizaki, Yukie Masui, Yasumichi Arai, Hiroki Inagaki, Madoka Ogawa, Saori Yasumoto, Hajime Iwasa, Kei Kamide, Hiromi Rakugi, Kazunori Ikebe, and Yasuyuki Gondo
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Polypharmacy ,Neuroticism ,Extraversion ,Lifestyle-related disease ,Psychosocial characteristics ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background Polypharmacy is a serious concern among older adults and is frequently related to adverse outcomes, including health problems, reduced quality of life, and increased medical expenses. Although personality traits are associated with health behaviors and diseases, the effect of polypharmacy on personality traits is unclear. Therefore, we examined the association of personality traits with polypharmacy among community-dwelling older adults. Methods This cross-sectional study analysed data on 836 community-dwelling older adults aged 69–71 years who participated in the Japanese longitudinal cohort study of Septuagenarians, Octogenarians, and Nonagenarians Investigation with Centenarians. Polypharmacy was defined as the intake of ≥ 5 medications concurrently. Personality traits were assessed using the Japanese version of the NEO-Five-Factor Inventory (NEO-FFI). A five-factor model of personality traits, including “neuroticism,” “extraversion,” “openness,” “agreeableness,” and “conscientiousness,” was measured by the NEO-FFI. Results The average number of medications was about 3 in both men and women. Among the participants, polypharmacy was observed in 23.9% of men and 28.0% of women. Multivariable logistic regression analysis showed that neuroticism (adjusted odds ratio [aOR] per 1 point increase = 1.078, 95% confidence interval [CI] = 1.015–1.144) in men and extraversion (aOR = 0.932, 95% CI = 0.884–0.983) in women were associated with polypharmacy. Conclusions Higher neuroticism in men and lower extraversion in women were associated with polypharmacy. This study suggests that personality traits may be involved in the process leading to the development of polypharmacy. Information on individual personality traits may help medical professionals in decision-making regarding medication management for lifestyle-related diseases.
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- 2022
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7. Alcohol drinking patterns have a positive association with cognitive function among older people: a cross-sectional study
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Yuya Akagi, Mai Kabayama, Yasuyuki Gondo, Yukie Masui, Saori Yasumoto, Nonglak Klinpudtan, Werayuth Srithumsuk, Kayo Godai, Kazunori Ikebe, Hiroshi Akasaka, Serina Yokoyama, Yoichi Nozato, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Ken Sugimoto, Yasumichi Arai, Hiroki Inagaki, Tatsuro Ishizaki, Hiromi Rakugi, and Kei Kamide
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Alcohol drinking patterns ,Cognitive function ,Older people ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background The relationship between moderate alcohol drinking or other alcohol drinking patterns such as frequency, beverage type, and situation of drinking and cognitive function is not sufficiently clear in older people. The purpose of this study was to investigate the association between alcohol drinking patterns and cognitive function in community-dwelling Japanese people aged 75 and over. Methods This study was a cross-sectional design based on a prospective cohort study called the SONIC study. Subjects were older people aged 75-77 or 85-87 who voluntarily participated in 2016-2017. Drinking information was collected for daily drinking frequency, daily drinking intake, beverage type, and non-daily drinking opportunity. Cognitive function was measured using the Japanese version of the Montreal Cognitive Assessment (MoCA-J). Other potential confounding factors evaluated were age, sex, medical factors, and psychosocial factors. An analysis of covariance was performed to evaluate the MoCA-J score relative to drinking frequency or alcohol intake. Multiple regression analysis was performed to investigate the association between beverage type or non-daily drinking opportunity and the MoCA-J score. Results The final number of participants analyzed was 1,226. The MoCA-J score for participants who reported drinking alcohol 1–6 days/week was significantly higher than that for those who reported drinking none or every day. No significant difference in the MoCA-J score was observed relative to daily alcohol intake. In terms of beverage type, wine was associated positively with the MoCA-J score. Non-daily drinking opportunity was also associated positively with the MoCA-J score. Conclusions Moderate-frequency drinking, wine consumption, and non-daily drinking opportunities were associated with higher cognitive function in community-dwelling Japanese aged 75 and over. Further longitudinal studies are needed to clarify the causal relationships.
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- 2022
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8. Older Adults’ Resilience Against Impact of Lifestyle Changes During the COVID-19 Pandemic
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Ayaka Kasuga, Saori Yasumoto, Takeshi Nakagawa, Yoshiko Ishioka, Akari Kikuchi, Hiroki Inagaki, Madoka Ogawa, Noriko Hori, Yukie Masui, Hwang Choe, Hiroyuki Muto, Mai Kabayama, Kayo Godai, Kazunori Ikebe, Kei Kamide, Tatsuro Ishizaki, and Yasuyuki Gondo
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Geriatrics ,RC952-954.6 - Abstract
Background: Older adults were expected to experience a decline in physical activities and an increase in social isolation during the COVID-19 pandemic. Methods: We investigated the changes in living conditions of 508 older adults (79.70 years ± 0.88) before (from July to December 2019) and during (in August 2020) the pandemic. We compared the mean score for the same individual instrumental activities of daily living (IADL), frequency of going out, exercise, and social interaction at two-time points. We also examined the influence of living arrangement (living alone or not) on the frequency of exercise and social interaction. Results: The frequency of going out decreased during the pandemic (in 2020); however, there was no significant change in IADL. The frequency of exercise and social interaction increased irrespective of the living arrangement. The frequency of exercise increased more in those living alone. Conclusions: Although older adults refrained from going out, they compensated for the risks of inactivity in daily life by increasing or maintaining their frequency of exercise and social interactions. The view that “older adults have a poor ability to accommodate the lifestyle changes during the COVID-19 pandemic” may be a stereotypical assumption.
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- 2022
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9. Living on the edge of the community: factors associated with discontinuation of community living among people with cognitive impairment
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Chiaki Ura, Tsuyoshi Okamura, Mika Sugiyama, Fumiko Miyamae, Mari Yamashita, Riko Nakayama, Ayako Edahiro, Tsutomu Taga, Hiroki Inagaki, Madoka Ogawa, and Shuichi Awata
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Cognitive impairment ,Community-dwelling elderly ,Discontinuation of community living ,Housing ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background As Japanese society continues to age, the isolation of older people is increasing, and community living for people with cognitive impairment is becoming more difficult. However, the challenges faced by people with cognitive impairment living in the community have not been fully explored because of methodological difficulties. This study re-accessed people with cognitive impairment identified in a previous epidemiological survey to explore their current situation and the risk factors associated with all-cause discontinuation of community living. Methods Under a community-based participatory framework, we examined a high-risk approach for people with cognitive impairment and a community action approach in parallel, to build a dementia-friendly community. For the high-risk approach, we achieved stepwise access to 7614 older residents, which enabled us to select and visit the homes of 198 participants with a Mini-Mental State Examination score
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- 2021
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10. Normative Data of the Trail Making Test Among Urban Community-Dwelling Older Adults in Japan
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Hiroyuki Suzuki, Naoko Sakuma, Momoko Kobayashi, Susumu Ogawa, Hiroki Inagaki, Ayako Edahiro, Chiaki Ura, Mika Sugiyama, Fumiko Miyamae, Yutaka Watanabe, Shoji Shinkai, and Shuichi Awata
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Trail Making Test ,normative data ,older adults ,cognitive decline ,neurocognitive assessment ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
IntroductionPopulation aging is likely to increase the number of people with dementia living in urban areas. The Trail Making Test (TMT) is widely used as a cognitive task to measure attention and executive function among older adults. Normative data from a sample of community-dwelling older adults are required to evaluate the executive function of this population. The purpose of this study was to examine the Trail Making Test completion rate and completion time among urban community-dwelling older adults in Japan.MethodsA survey was conducted at a local venue or during a home visit (n = 1,966). Cognitive tests were conducted as a part of the survey, and TMT Parts A (TMT-A) and B (TMT-B) were completed after the completion of the Japanese version of the Mini-Mental State Examination (MMSE-J). Testers recorded TMT completion status, completion time, and the number of errors observed.ResultsIn the TMT-A, 1,913 (99.5%) participants understood the instructions, and 1,904 (99.1%) participants completed the task within the time limit of 240 s. In the TMT-B, 1,839 (95.9%) participants understood the instructions, and 1,584 (82.6%) participants completed the task within the time limit of 300 s. The completion rate of TMT-B was 90.2 and 41.8% for participants with an MMSE-J score of >23 points and ≦23 points, respectively. Results of multiple regression analyses showed that age, education, and the MMSE-J score were associated with completion time in both TMTs.ConclusionIn both TMTs, completion time was associated with age, education, and general cognitive function. However, not all participants completed the TMT-B, and the completion rate was relatively low among participants with low MMSE-J scores. These findings may help interpret future TMT assessments.
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- 2022
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11. Associations of cardiovascular biomarkers and plasma albumin with exceptional survival to the highest ages
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Takumi Hirata, Yasumichi Arai, Shinsuke Yuasa, Yukiko Abe, Michiyo Takayama, Takashi Sasaki, Akira Kunitomi, Hiroki Inagaki, Motoyoshi Endo, Jun Morinaga, Kimio Yoshimura, Tetsuo Adachi, Yuichi Oike, Toru Takebayashi, Hideyuki Okano, and Nobuyoshi Hirose
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Science - Abstract
Supercentenarians are approaching the current longevity limit by avoiding or surviving major illness, thus identifying biomarkers for exceptional survival might provide insights into the protection against disease of aging. Here, the authors show low NT-proBNP and high albumin in plasma are the biological correlates of survival to the highest ages.
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- 2020
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12. Everyday challenges facing high-risk older people living in the community: a community-based participatory study
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Tsuyoshi Okamura, Chiaki Ura, Mika Sugiyama, Madoka Ogawa, Hiroki Inagaki, Fumiko Miyamae, Ayako Edahiro, Yukiko Kugimiya, Mutsuko Okamura, Mari Yamashita, and Shuichi Awata
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Dementia ,Cognitive impairment ,Community care ,Social support ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background Considering the real-world experiences of those with cognitive impairments is important in building a positive community for older people. Community-based participatory research is an important methodology for investigators focused on improving community health. The aim of this study was to 1) investigate factors associated with the continuation of community dwelling among high-risk older people and 2) to create a model of an inclusive community space for older people in the largest housing complex district in Tokyo. Methods From 198 residents who completed all three steps (mail, face-to-face, and home-visit) of a previous large-scale epidemiological survey, we identified 66 residents who were at high-risk of moving out of the community. These participants underwent 6 months of regular assessments by experienced researchers to identify the factors associated with continuing to live in the community. We also employed a community action approach to develop a community space for residents in the study district where more than two researchers who were medical professionals served as staff. The services offered by the space were continuously improved according to user feedback. The function of this center was evaluated during interdisciplinary research meetings. Results After 6 months, among the 66 high-risk residents, 49 people were living in the community and 12 people had moved out of the community. Those who could not continue to live in the community had greater unmet needs in terms of social support, especially daily living support and housing support. In addition, their families perceived a heavier burden of care. Interestingly, dementia diagnosis via the DSM-5, clinical dementia rating, physical health, mental health, and long-term care usage did not predict the outcome. Through discussions with guests, we equipped the space with various services such as coordination of community care and networking with existing organizations. Conclusions Merely providing healthcare and long-term care might not be sufficient to support community living in people with cognitive impairments. Daily living support and housing support should be provided in the context of a broad health services package. For this purpose, creating a comfortable community space for residents and community workers is essential.
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- 2020
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13. The importance of stroke as a risk factor of cognitive decline in community dwelling older and oldest peoples: the SONIC study
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Werayuth Srithumsuk, Mai Kabayama, Yasuyuki Gondo, Yukie Masui, Yuya Akagi, Nonglak Klinpudtan, Eri Kiyoshige, Kayo Godai, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Kazunori Ikebe, Madoka Ogawa, Hiroki Inagaki, Tatsuro Ishizaki, Yasumichi Arai, Hiromi Rakugi, and Kei Kamide
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Stroke ,Cognitive decline ,Older and oldest people ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background Cognitive impairment is a major health concern among older and oldest people. Moreover, stroke is a relevant contributor for cognitive decline and development of dementia. The study of cognitive decline focused on stroke as the important risk factor by recruiting older and oldest is still lagging behind. Therefore, the aim of this study was to investigate the importance of stroke as a risk factor of cognitive decline during 3 years in community dwelling older and oldest people. Methods This study was longitudinal study with a 3-year follow-up in Japan. The participants were 1333 community dwelling older and oldest people (70 years old = 675, 80 years old = 589, and 90 years old = 69). Data collected included basic data (age, sex, and history of stroke), vascular risk factors (hypertension, diabetes mellitus, dyslipidemia, atrial fibrillation, and current smoking), and social factors (educational level, frequency of going outdoors, long-term care (LTC) service used, and residential area). The Japanese version of the Montreal Cognitive Assessment (MoCA-J) was decline of ≥2 points was defined as cognitive decline. Multiple logistic regression analysis was used to investigate the association between stroke and other risk factors with cognitive decline during a 3-year follow-up. Results The fit of the hypothesized model by multiple logistic regression showed that a history of stroke, advanced age, and greater MoCA-J score at the baseline were important risk factors, while the presence of dyslipidemia and a higher educational level were protective factors that were significantly correlated with cognitive decline during the 3-year follow-up. Conclusions The cognitive decline after the 3-year follow-up was influenced by the history of stroke and advanced age, while greater MoCA-J score at the baseline was positively associated with subsequent 3 years cognitive decline. The protective factors were the presence of dyslipidemia and a higher educational level. Therefore, these factors are considered important and should be taken into consideration when searching for creative solutions to prevent cognitive decline after stroke in community dwelling older and oldest people.
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- 2020
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14. The relationship between blood pressure and cognitive function
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Joji Ishikawa, Satoshi Seino, Akihiko Kitamura, Ayumi Toba, Kenji Toyoshima, Yoshiaki Tamura, Yutaka Watanabe, Yoshinori Fujiwara, Hiroki Inagaki, Shuichi Awata, Shoji Shinkai, Atsushi Araki, and Kazumasa Harada
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Blood pressure ,Cognitive impairment ,Dementia ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background: Although an elevated systolic blood pressure (SBP) is associated with cognitive dysfunction, BP may decrease with advanced cognitive dysfunction; therefore, we attempted to identify the turning point in the relationship between cognitive function and SBP in elderly subjects. Methods: In pooled datasets of general populations and outpatient clinics (age>65 years), in which the risk of frailty or cognitive dysfunction was assessed (N = 4076), the relationship between SBP and the Mini Mental State Examination (MMSE) score was examined. Results: Mean age was 72.5 ± 6.2 years (male 45.1%), and SBP was 133.0 ± 19.5 mmHg. In an analysis of locally weighted scatter plot smoothing, the relationship between SBP and MMSE scores changed at an MMSE score of 24 points. In subjects with preserved cognitive function (MMSE ≥24 points), MMSE scores decreased with increases in SBP (B = −0.047 per 10 mmHg increase, P = 0.002) after adjustments for age, sex, body mass index, alcohol habit, smoking status, diabetes, a history of stroke, and the geriatric nutritional index; however, in subjects with reduced cognitive function (MMSE
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- 2021
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15. Age group differences in association between IADL decline and depressive symptoms in community-dwelling elderly
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Eri Kiyoshige, Mai Kabayama, Yasuyuki Gondo, Yukie Masui, Hiroki Inagaki, Madoka Ogawa, Takeshi Nakagawa, Saori Yasumoto, Hiroshi Akasaka, Ken Sugimoto, Kazunori Ikebe, Yasumichi Arai, Tatsuro Ishizaki, Hiromi Rakugi, and Kei Kamide
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Instrumental activities of daily living ,Depressive symptoms ,Age group ,Community-dwelling people ,Older adults ,Multiple group analysis ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background Instrumental Activities of Daily Living (IADL) is an indicator of whether a community-dwelling elderly can live independently. IADL decline was reported to be associated with aging and depression. The present study aimed to investigate whether the association between IADL decline and depressive symptoms differs with aging, using two age groups of community-dwelling Japanese elderly in their 70s and 80s. Methods We conducted longitudinal analysis among participants in their 70s and 80s at the baseline from Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians (SONIC) study. IADL was assessed by The Tokyo Metropolitan Institute of Gerontology (TMIG) index of competence. As a main predictor, depressive symptoms were measured by the five-item version of the Geriatrics Depression Scale (GDS-5). As possible confounders, we considered cognitive function, body mass index, solitary living, education, economic status, medical history of stroke and heart disease, hypertension, dyslipidemia, diabetes, and sex. We obtained odds ratios (ORs) of IADL decline for having depressive symptoms in each age group (70s/80s) and tested interactions between depressive symptoms and age groups in relation to IADL decline in 3 years by logistic regression. Additionally, to confirm age group differences, we conducted multiple group analysis. Results There were 559 participants in their 70s and 519 in their 80s. Compared to participants without depressive symptoms, those with depressive symptoms had higher OR of IADL decline in 70s (OR [95% CI] = 2.33 [1.13, 4.78]), but not in 80s (OR [95% CI] = 0.85 [0.46, 1.53]). There were significant interactions between depressive symptoms and age groups in relation to IADL decline (p-value = 0.03). Multiple group analyses showed differences between the age groups by Akaike information criterion (AIC), and ORs (95%CI) decline for depressive symptoms was 2.33 (1.14, 4.77) in 70s and 0.85 (0.47, 1.54) in 80s. Conclusion The association of depressive symptoms and IADL decline during the 3 years was significantly different between the 70s and 80s age groups, and significant association was found only in people in their 70s. Detecting depressive symptoms may be a key for preventing IADL decline in people in their 70s and not for those in their 80s.
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- 2019
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16. Does community social capital buffer the relationship between educational disadvantage and cognitive impairment? A multilevel analysis in Japan
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Hiroshi Murayama, Fumiko Miyamae, Chiaki Ura, Naoko Sakuma, Mika Sugiyama, Hiroki Inagaki, Tsuyoshi Okamura, and Shuichi Awata
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Buffering effect ,Cognitive impairment ,Japan ,Multilevel analysis ,Older people ,Social capital ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background This study explored the relationship between community social capital and cognitive impairment, with a focus on the buffering role of community social capital in the association between educational disadvantage and cognitive impairment in community-dwelling older adults in Japan. Methods We used data from two population-based, cross-sectional surveys targeting people aged ≥65 years in a suburban city of the Tokyo metropolitan area (n = 897; 49.8% men; average age = 74.4 years). Social capital included social support (emotional and instrumental support) and the strength of social networks (neighborly ties). To create district-level social capital indicators, we aggregated individual responses on social capital within each district. The Mini-Mental State Examination, Japanese version was used for the assessment of cognitive function. Results Using multilevel logistic regression analysis, we found that lower amounts of district-level emotional and instrumental support were associated with a greater likelihood of cognitive impairment among men. For women, district-level emotional support was associated with a greater likelihood of cognitive impairment. Additionally, a strong district-level social network buffered the relationship between low education and cognitive impairment in both sexes. Conclusions Community social capital appears to have a protective role in determining cognitive function in old age. Our findings may facilitate the development of new community-based strategies to combat dementia.
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- 2019
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17. The Differential Effects of Age on the Association Between Childhood Socioeconomic Disadvantage and Subjective Symptoms of Dementia Among Older Japanese People
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Hiroshi Murayama, Mika Sugiyama, Hiroki Inagaki, Chiaki Ura, Fumiko Miyamae, Ayako Edahiro, Keiko Motokawa, Tsuyoshi Okamura, and Shuichi Awata
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dementia ,subjective symptoms ,childhood ,socioeconomic status ,lifecourse ,Japan ,Medicine (General) ,R5-920 - Abstract
Background: Despite increasing evidence of an association between childhood socioeconomic disadvantage and cognitive outcomes, such as dementia and cognitive decline, in Western countries, there are no studies on this association from non-Western societies. We investigated the relationship between childhood socioeconomic status (SES) and subjective symptoms of dementia among community-dwelling older Japanese people and examined age and sex variations in this association. Methods: Data were derived from a cross-sectional survey for all community-dwelling individuals aged 65 years and over in Adachi, Tokyo (n = 132,005). We assessed subjective dementia symptoms using a self-administered dementia checklist, which was validated by comparison with the Clinical Dementia Rating scale. Results: Data from 75,358 questionnaires were analyzed. After adjusting for potential covariates, lower childhood SES was associated with greater likelihood of subjective dementia symptoms. We found a significant interaction between childhood SES and age on subjective dementia symptoms but no interaction between childhood SES and sex. Age-stratified analysis indicated that the association between lower childhood SES and subjective dementia symptoms was stronger in the ≥75 years subgroup than in the 65–74 years subgroup, indicating an effect modification of age on this association. Conclusions: Our findings suggested that low SES in childhood might have a long-term influence on dementia symptoms in late life and that this influence varied by age. This differential association might be explained by the social and historical context in Japan (ie, World War II, postwar chaos, and high economic growth) that has shaped participants’ early experiences.
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- 2019
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18. Nutritional status and body composition in cognitively impaired older persons living alone: The Takashimadaira study.
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Masanori Iwasaki, Keiko Motokawa, Yutaka Watanabe, Misato Hayakawa, Yurie Mikami, Maki Shirobe, Hiroki Inagaki, Ayako Edahiro, Yuki Ohara, Hirohiko Hirano, Shoji Shinkai, and Shuichi Awata
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Medicine ,Science - Abstract
ObjectivesTo investigate nutritional status and body composition in cognitively impaired older persons living alone.MethodsThis cross-sectional study included 1051 older adults (633 women and 418 men, mean age: 77.1 years) from the Takashimadaira study. The study participants were categorized according to whether they lived alone, which was confirmed via questionnaire, and had cognitive impairment, which was defined as having a Mini Mental State Examination-Japanese score ≤23. Nutritional status was evaluated using the serum albumin level. The fat-free mass index (FFMI) was calculated based on anthropometric and body composition measurements. A logistic regression model with the outcome of a low serum albumin level (serum albumin ResultsThe percentages of participants in the living alone (-)/cognitive impairment (-) group, the living alone (+)/cognitive impairment (-) group, the living alone (-)/cognitive impairment (+) group, and the living alone (+)/cognitive impairment (+) group were 54.8%, 37.3%, 5.6%, and 2.3%, respectively. Compared to the living alone (-)/cognitive impairment (-) group, the living alone (+)/cognitive impairment (+) group was more likely to have a low serum albumin level (adjusted odds ratio = 3.10, 95% confidence interval = 1.31 to 7.33) and low FFMI (adjusted odds ratio = 2.79, 95% confidence interval = 1.10 to 7.06) after adjusting for potential confounders.ConclusionCognitively impaired older adults living alone had poorer nutrition than cognitively normal and cohabitating persons in this study. Our results highlight the importance of paying extra attention to nutritional status for this group of community-dwelling older adults.
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- 2021
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19. Use of healthcare services and assistive devices among centenarians: results of the cross-sectional, international5-COOP study
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Marie Herr, Julien Dupraz, Karen Andersen-Ranberg, Stefan Fors, Francois R Herrmann, Tomoko Wakui, Bernard Jeune, Jean-Marie Robine, Yasuhiko Saito, Anna Oksuzyan, Frederic Balard, Yasumichi Arai, Nobuyoshi Hirose, Yukie Masui, Hiroki Inagaki, Yasuyuki Gondo, Kei Kamide, Craig Willcox, Ikuya Ashitomi, Shotoku Yasura, Makoto Suzuki, Marti Parker, Mats Thorslund, Bettina Meinow, Fred Paccaud, and Dina Zekri
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Medicine - Abstract
ObjectivesTo measure the use of healthcare services and assistive devices by centenarians in five countries.DesignCross-sectional study using a survey questionnaire.SettingCommunity-dwelling and institutionalised centenarians living in Japan, France, Switzerland, Sweden and Denmark.Participants1253 participants aged 100 or in their 100th year of life, of whom 1004 (80.1%) were female and 596 (47.6%) lived in institutions.Main outcome measuresRecent use of medical visits, nursing care at home, home-delivered meals, acute care hospital stays overnight, professional assessments such as sight tests, mobility aids and other assistive devices. A set of national healthcare system indicators was collected to help interpret differences between countries.ResultsThere was considerable variability in the healthcare services and assistive devices used by centenarians depending on their country and whether they were community-dwelling or institutionalised. In contrast to the relatively homogeneous rates of hospitalisation in the past year (around 20%), community-dwelling centenarians reported widely ranging rates of medical visits in the past 3 months (at least one visit, from 32.2% in Japan to 86.6% in France). The proportion of community-dwellers using a mobility device to get around indoors (either a walking aid or a wheelchair) ranged from 48.3% in Japan to 79.2% in Sweden. Participants living in institutions and reporting the use of a mobility device ranged from 78.6% in Japan to 98.2% in Denmark.ConclusionsOur findings suggest major differences in care received by centenarians across countries. Some may result from the characteristics of national healthcare systems, especially types of healthcare insurance coverage and the amounts of specific resources available. However, unexplored factors also seem to be at stake and may be partly related to personal health and cultural differences.
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- 2020
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20. Relationship between Eating Alone and Poor Appetite Using the Simplified Nutritional Appetite Questionnaire
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Yurie Mikami, Keiko Motokawa, Maki Shirobe, Ayako Edahiro, Yuki Ohara, Masanori Iwasaki, Misato Hayakawa, Yutaka Watanabe, Hiroki Inagaki, Hunkyung Kim, Shoji Shinkai, Shuichi Awata, and Hirohiko Hirano
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eating alone ,poor appetite ,SNAQ ,community-dwelling ,nutrition ,Nutrition. Foods and food supply ,TX341-641 - Abstract
One prominent factor associated with malnutrition is poor appetite. In Japan, the number of older adults living alone has increased annually. Those living alone tended to eat alone, which may lead to poor appetite. This study aimed to investigate the association between eating alone and poor appetite using an index called the Simplified Nutritional Appetite Questionnaire (SNAQ). We surveyed 818 people aged 70 and over in Takashimadaira, Itabashi-ku, Tokyo, Japan, in 2016. Comparisons were made between two groups, a poor appetite group (n = 295) and a good appetite group (n = 523), and results indicate that the poor appetite group had a higher rate of eating alone than the good appetite group (38.0% vs. 20. 1%: p < 0.001). Multivariable logistic regression (OR; 95%CI) was performed and poor appetite was significantly associated with the Geriatric Depression Scale (GDS) score (1.707; 1.200–2.427), the number of medications (1.061; 1.007–1.118), JST score (0.894; 0.841–0.950), the indication of “very healthy” on a self-rated health scale (0.343; 0.152–0.774), and reports of eating alone (1.751; 1.130–2.712). Our results suggest that eating alone is associated with a poor appetite.
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- 2022
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21. Association between dietary patterns and cognitive function among 70-year-old Japanese elderly: a cross-sectional analysis of the SONIC study
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Hitomi Okubo, Hiroki Inagaki, Yasuyuki Gondo, Kei Kamide, Kazunori Ikebe, Yukie Masui, Yasumichi Arai, Tatsuro Ishizaki, Satoshi Sasaki, Takeshi Nakagawa, Mai Kabayama, Ken Sugimoto, Hiromi Rakugi, Yoshinobu Maeda, and SONIC Study Group
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Cognitive function, Dietary pattern ,Factor analysis ,Japanese ,Elderly ,Nutrition. Foods and food supply ,TX341-641 ,Nutritional diseases. Deficiency diseases ,RC620-627 - Abstract
Abstract Background An increasing number of studies in Western countries have shown that healthy dietary patterns may have a protective effect against cognitive decline and dementia. However, information on this relationship among non-Western populations with different cultural settings is extremely limited. We aim to examine the relationship between dietary patterns and cognitive function among older Japanese people. Methods This cross-sectional study included 635 community-dwelling people aged 69–71 years who participated in the prospective cohort study titled Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians (SONIC). Diet was assessed over a one-month period with a validated, brief-type, self-administered diet history questionnaire. Dietary patterns from thirty-three predefined food groups [energy-adjusted food (g/d)] were extracted by factor analysis. Cognitive function was assessed using the Japanese version of the Montreal Cognitive Assessment (MoCA-J). Multivariate regression analysis was performed to examine the relationship between dietary patterns and cognitive function. Results Three dietary patterns were identified: the ‘Plant foods and fish’, ‘Rice and miso soup’, and ‘Animal food’ patterns. The ‘Plant foods and fish’ pattern, characterized by high intakes of green and other vegetables, soy products, seaweeds, mushrooms, potatoes, fruit, fish, and green tea, was significantly associated with a higher MoCA-J score [MoCA-J score per one-quartile increase in dietary pattern: β = 0.56 (95% CI: 0.33, 0.79), P for trend
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- 2017
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22. Overlap Between Apolipoprotein Eε4 Allele and Slowing Gait Results in Cognitive Impairment
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Ryota Sakurai, Yutaka Watanabe, Yosuke Osuka, Yu Taniguchi, Hisashi Kawai, Hunkyung Kim, Akihiko Kitamura, Hiroki Inagaki, Manuel Montero-Odasso, Shuichi Awata, and Shoji Shinkai
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apolipoprotein E ,slow gait ,cognitive impairment ,aging ,older adults ,cohort study ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Background: Although apolipoprotein E polymorphism ε4 allele (ApoE4) and slow gait are well-known risk factors for cognitive impairment, examination of their combined effect on cognitive function is lacking. Our objective was to elucidate whether a combination of ApoE4 phenotyping and slow gait resulted in greater cognitive impairment.Methods: Overall, 1,085 community-dwelling older adults, either ApoE4 carriers (n = 167, 15.4%) or non-ApoE4 carriers, were included from the “Takashimadaira study.” Gait speed was assessed with an electronic walkway and slow gait was defined as
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- 2019
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23. Characteristics for gait parameters of community-dwelling elderly Japanese with lower cognitive function.
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Yu Taniguchi, Yutaka Watanabe, Yosuke Osuka, Akihiko Kitamura, Satoshi Seino, Hunkyung Kim, Hisashi Kawai, Ryota Sakurai, Hiroki Inagaki, Shuichi Awata, and Shoji Shinkai
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Medicine ,Science - Abstract
OBJECTIVES:Recent studies reported that several gait parameters were associated with lower cognitive function or cognitive decline, however, known gait parameters were limited and no study has used large-scale data. We identified the characteristics for gait parameters of community-dwelling elderly Japanese with lower cognitive function. METHODS:1,240 community-dwelling adults (mean [SD] age, 77.2 [4.8] years; women, 59.4%) aged 70 or older participated in geriatric health assessments in 2016. We measured comprehensive gait parameters using resistive pressure platform. Cognition was assessed by Mini-Mental State Examination (MMSE). RESULTS:There are possible correlations between gait measures (gait speed, stride length, step length, step width, average foot pressure, double support duration, and single support duration) and CVs (CV of stride length, step length, average foot pressure, and single support duration) with MMSE score, respectively. After adjustment for important confounders, multiple regression models showed that gait speed (β = .080, p = 0.006), stride length (β = .123, p
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- 2019
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24. The impact of leisure activities on older adults' cognitive function, physical function, and mental health.
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Giovanni Sala, Daniela Jopp, Fernand Gobet, Madoka Ogawa, Yoshiko Ishioka, Yukie Masui, Hiroki Inagaki, Takeshi Nakagawa, Saori Yasumoto, Tatsuro Ishizaki, Yasumichi Arai, Kazunori Ikebe, Kei Kamide, and Yasuyuki Gondo
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Medicine ,Science - Abstract
Engagement in leisure activities has been claimed to be highly beneficial in the elderly. Practicing such activities is supposed to help older adults to preserve cognitive function, physical function, and mental health, and thus to contribute to successful aging. We used structural equation modeling (SEM) to analyze the impact of leisure activities on these constructs in a large sample of Japanese older adults (N = 809; age range 72-74). The model exhibited an excellent fit (CFI = 1); engaging in leisure activities was positively associated with all the three successful aging indicators. These findings corroborate previous research carried out in Western countries and extend its validity to the population of Eastern older adults. Albeit correlational in nature, these results suggest that active engagement in leisure activities can help older adults to maintain cognitive, physical, and mental health. Future research will clarify whether there is a causal relationship between engagement in leisure activities and successful aging.
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- 2019
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25. Low Dietary Variety and Diabetes Mellitus Are Associated with Frailty among Community-Dwelling Older Japanese Adults: A Cross-Sectional Study
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Misato Hayakawa, Keiko Motokawa, Yurie Mikami, Kaori Yamamoto, Maki Shirobe, Ayako Edahiro, Masanori Iwasaki, Yuki Ohara, Yutaka Watanabe, Hisashi Kawai, Motonaga Kojima, Shuichi Obuchi, Yoshinori Fujiwara, Hunkyung Kim, Kazushige Ihara, Hiroki Inagaki, Shoji Shinkai, Shuichi Awata, Atsushi Araki, and Hirohiko Hirano
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frailty ,diabetes ,Dietary Variety Score ,Nutrition. Foods and food supply ,TX341-641 - Abstract
The association between dietary diversity and frailty remains unknown in older people. We evaluated whether a limited dietary variety is associated with frailty in older adults with diabetes mellitus (DM). This cross-sectional investigation included 1357 adults (median age: 77 years, women: 61.3%). DM was determined by self-reporting, the Dietary Variety Score (DVS) was used to evaluate dietary variety, and the revised Japanese version of the Cardiovascular Health Study criteria evaluated frailty. Participants were divided into 4 groups: no DM/high DVS (non-DMHV), no DM/low DVS (non-DMLV), DM/high DVS (DMHV), and DM/low DVS (DMLV). The prevalence of frailty in each group was 3.6%, 6.7%, 6.7%, and 12.2%. After adjusting for covariates, logistic regression analysis revealed the highest odds ratio (OR) of frailty in the DMLV (non-DMLV, OR = 2.18 (95% confidence interval (CI): 1.25–3.83); DMHV, OR = 1.87 (95% CI: 0.63–5.52); DML, OR = 5.03 (95% CI: 2.05–12.35)). Another logistic regression analysis revealed that a low DVS and DM were independently associated with frailty. Both a low dietary variety and DM were independently related to frailty in older people and the combination increased the prevalence of frailty. These findings suggest that high dietary variety could be important for the prevention of frailty in people with DM.
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- 2021
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26. Occlusal force is correlated with cognitive function directly as well as indirectly via food intake in community-dwelling older Japanese: From the SONIC study.
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Kazunori Ikebe, Yasuyuki Gondo, Kei Kamide, Yukie Masui, Taturo Ishizaki, Yasumichi Arai, Hiroki Inagaki, Takeshi Nakagawa, Mai Kabayama, Hirochika Ryuno, Hitomi Okubo, Hajime Takeshita, Chisato Inomata, Yuko Kurushima, Yusuke Mihara, Kohdai Hatta, Motoyoshi Fukutake, Kaori Enoki, Taiji Ogawa, Ken-Ichi Matsuda, Ken Sugimoto, Ryosuke Oguro, Yoichi Takami, Norihisa Itoh, Yasushi Takeya, Koichi Yamamoto, Hiromi Rakugi, Shinya Murakami, Masahiro Kitamura, and Yoshinobu Maeda
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Medicine ,Science - Abstract
Growing evidence suggests that oral health may be an important factor associated with cognitive function in aged populations. However, many previous studies on this topic used insensitive oral indicators or did not include certain essential covariates. Thus, we examined the association between occlusal force and cognitive function in a large sample of older adults, controlling for dietary intake, vascular risk factors, inflammatory biomarkers, depression, and genetic factors.In this cross-sectional study of older community-dwelling Japanese adults, we examined data collected from 994 persons aged 70 years and 968 persons aged 80 years. Cognitive function was measured using the Japanese version of the Montreal Cognitive Assessment (MoCA-J). Oral status and function were evaluated according to the number of remaining teeth, periodontal pocket depth, and maximal occlusal force. Associations between MoCA-J scores and occlusal force were investigated via bivariate and multivariate analyses.Education level, financial status, depression score, and intake of green and yellow vegetables, as well as number of teeth and occlusal force, were significantly correlated with MoCA-J scores in both age groups. Among individuals aged 80 years, CRP and periodontal status were weakly but significantly associated with MoCA-J score. After controlling for all significant variables via bivariate analyses, the correlation between maximal occlusal force and cognitive function persisted. A path analysis confirmed the hypothesis that cognitive function is associated with occlusal force directly as well as indirectly via food intake.After controlling for possible factors, maximal occlusal force was positively associated with cognitive function directly as well as indirectly through dietary intake.
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- 2018
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27. Development of the Japan Science and Technology Agency Index of Competence to Assess Functional Capacity in Older Adults
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Hajime Iwasa PhD, Yukie Masui PhD, Hiroki Inagaki PhD, Yuko Yoshida PhD, Hiroyuki Shimada PhD, RPT, Rika Otsuka MA, Kazunori Kikuchi MA, Kumiko Nonaka PhD, Hiroto Yoshida PhD, Hideyo Yoshida MD, PhD, and Takao Suzuki MD, PhD
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Geriatrics ,RC952-954.6 - Abstract
Improvement in the health of older people and changes in their lifestyles necessitate a scale that can better measure their competence at a higher level. This study describes the development process of the Japan Science and Technology Agency Index of Competence (JST-IC) by (a) refining conceptual definitions and developing preliminary items and (b) examining the basic properties of the items. Participants were 1,253 septuagenarians (539 men and 714 women) living in communities, who were asked to judge whether they were independent via 88 items. To examine the basic properties of the preliminary items, five different analyses were conducted. Thirty-four items were considered as inappropriate (6 overlapped between the analyses): (a) 9 due to very high or low ratios of responders who answered “yes,” (b) 4 due to gender or regional differences, (c) 5 due to their weak association with health status, (d) 9 due to low communalities in factor analysis, and (e) 13 due to redundancy of meaning with other items. Conceptual definitions and preliminary items were developed, and the basic properties of the items were examined to create the JST-IC. The next step would be to screen the remaining 54 items to create the final version of the scale.
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- 2015
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28. Population-based reference values for tongue pressure in Japanese older adults: A pooled analysis of over 5,000 participants
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Masanori, Iwasaki, Yuki, Ohara, Keiko, Motokawa, Misato, Hayakawa, Maki, Shirobe, Ayako, Edahiro, Yutaka, Watanabe, Shuichi, Awata, Tsuyoshi, Okamura, Hiroki, Inagaki, Naoko, Sakuma, Shuichi, Obuchi, Hisashi, Kawai, Manami, Ejiri, Kumiko, Ito, Yoshinori, Fujiwara, Akihiko, Kitamura, Yu, Nofuji, Takumi, Abe, Katsuya, Iijima, Tomoki, Tanaka, Bo-Kyung, Son, Shoji, Shinkai, and Hirohiko, Hirano
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Dentistry (miscellaneous) ,Oral Surgery - Abstract
To establish age- and sex-specific population reference values for tongue pressure (TP) in community-dwelling Japanese older adults.For this analysis, we pooled four population-based studies on community-dwelling adults aged ≥65 years that measured TP using a JMS tongue pressure measuring device. We calculated the means and deciles of TP per 5-year age group for each sex. We also estimated age trends in TP for men and women.In total, 5,083 individuals (2,150 men and 2,933 women, with a mean [standard deviation] age of 75.2 [6.5] years) were included in the present analysis. In male participants, the mean (standard deviation) TPs for ages 65-69, 70-74, 75-79, 80-84, and ≥85 years were 34.0 (8.4), 32.2 (8.1), 30.8 (8.3), 28.4 (8.9), and 24.4 (8.2) kPa, respectively. In female participants, the corresponding values were 31.5 (7.1), 30.5 (7.5), 29.6 (7.3), 28.4 (8.0), and 26.4 (7.6) kPa, respectively. For both sexes, there were significant declining trends in TP with advanced age. In addition, the interaction between age and sex had a significant effect on TP (regression coefficient [95% confidence interval] = -0.18 [-0.25 to -0.11] when age was modeled as a continuous variable and sex was modeled as a categorical variable [coded as 0=women, 1=men]).This study determined age- and sex-specific reference values for TP, presented as means and deciles, in community-dwelling Japanese older adults aged ≥65 years. This study also demonstrated sex differences in age-related declines in TP.
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- 2023
29. Associations between salivary testosterone levels and cognitive function among 70‐year‐old Japanese elderly: A cross‐sectional analysis of the <scp>SONIC</scp> study
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Kumi Hirokawa, Ayaka Kasuga, Kiyoaki Matsumoto, Yasuko Omori, Yukie Masui, Takeshi Nakagawa, Madoka Ogawa, Yoshiko Ishioka, Hiroki Inagaki, Kazunori Ikebe, Yasumichi Arai, Tatsuro Ishizaki, Kei Kamide, and Yasuyuki Gondo
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Male ,Stroke ,Cross-Sectional Studies ,Cognition ,Japan ,Humans ,Female ,Dementia ,Testosterone ,Cognitive Dysfunction ,General Medicine ,Aged - Abstract
This cross-sectional study aimed to investigate the associations between salivary testosterone concentrations and cognitive function in 70-year-old Japanese elderly people without dementia and stroke.Participants were 197 Japanese community-dwelling people aged 69-71 years. Their salivary samples were collected, and their cognitive function was assessed using the Japanese version of the Montreal Cognitive Assessment (MoCA-J). Participants were also administered a 10-item recall and a 24-item recognition test. The data for 179 (106 men and 73 women) individuals were analyzed, excluding individuals with a past history of stroke and dementia. Multivariate logistic regression analyses were performed after adjusting for lifestyle factors and analyzing data separately for men and women.MoCA-J scores showed that men with low testosterone concentrations had a significantly greater risk of low cognitive performance than those with high testosterone concentrations (adjusted odds ratio: 4.72, 95% confidence interval: 1.06-21.00), while no significant association was found in women. The 10-item recall test scores showed that higher testosterone concentrations were significantly associated with greater recall in the second trial in women (standardized beta = 0.24, P = 0.040), whereas no significant association was found in men. Salivary testosterone concentrations were positively associated with better cognitive performance in older men and women.The associations between salivary testosterone concentrations and cognitive function were shown by different tasks for men and women. Geriatr Gerontol Int 2022; 22: 1040-1046.
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- 2022
30. Criterion validity of the health assessment questionnaire for the national screening program for older adults in Japan: The <scp>SONIC</scp> study
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Noriko Hori, Tatsuro Ishizaki, Yukie Masui, Yuko Yoshida, Hiroki Inagaki, Kae Ito, Yoshiko L. Ishioka, Takeshi Nakagawa, Madoka Ogawa, Mai Kabayama, Kei Kamide, Kazunori Ikebe, Yasumichi Arai, and Yasuyuki Gondo
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General Medicine - Published
- 2023
31. Relationship between occlusal force and psychological frailty in Japanese community‐dwelling older adults: The Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians study
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Suzuna Akema, Tomoaki Mameno, Takeshi Nakagawa, Hiroki Inagaki, Motoyoshi Fukutake, Kodai Hatta, Yuki Murotani, Yoshitaka Tsujioka, Hiromasa Hagino, Kotaro Higashi, Toshihito Takahashi, Masahiro Wada, Yoshinobu Maeda, Yasuyuki Gondo, Kei Kamide, Mai Kabayama, Tatsuro Ishizaki, Yukie Masui, Soshiro Ogata, and Kazunori Ikebe
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Geriatrics and Gerontology - Published
- 2023
32. Living Alone, Cognitive Function, and Well-Being of Japanese Older Men and Women: A Cross-Sectional Study
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Shuji Tsuda, Hiroki Inagaki, Mika Sugiyama, Tsuyoshi Okamura, Fumiko Miyamae, Chiaki Ura, Ayako Edahiro, and Shuichi Awata
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Sociology and Political Science ,Article Subject ,Health Policy ,Public Health, Environmental and Occupational Health ,Social Sciences (miscellaneous) - Abstract
This study examined the interaction of living alone and cognitive decline in relation to the well-being of older men and women. We analyzed the data from a cross-sectional, self-administered questionnaire survey of community-dwelling older adults in Tokyo, who were aged 65+ and not on long-term care. The questionnaire included the 10-item self-administered dementia checklist (SDC), the WHO-5 Well-Being Scale, a question on their living arrangement, and participants’ baseline characteristics and social support and social contact. The analyses were stratified by sex and fitted with linear regression models with interaction. A total of 34,255 men and 41,056 women participated. Sample mean age was 73.5 (SD 6.1) for men and 73.6 (SD 6.0) for women, and 18.5% and 26.0% lived alone. The distribution of SDC scores indicated 95.9% and 97.0% had a cognitive status varying from intact to possible mild dementia. Cognitive decline showed a linear association with lower well-being in men (beta −0.53; 95% CI −0.58, −0.48; p < 0.001 ) and women (beta −0.38; 95% CI −0.42, −0.34; p < 0.001 ). Compared to men and women living with others, those living alone experienced lower well-being as their cognitive function declined, and the interactions (living arrangements ∗ SDC) were statistically significant. After controlling participants’ characteristics and social support and social contact, the interaction was significant in men ( p < 0.001 ) but not in women ( p = 0.46 ). Our findings support that older men and women living alone experience a slightly steeper downward trajectory of cognitive decline and poor well-being than their counterparts living with others. The unequivocal effects of controlling confounding factors between men and women indicate the need for gendered countermeasures by welfare services.
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- 2023
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33. Factors associated with psychological well‐being among nonagenarians: Well‐being in the era of 100 years of life
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Kae Ito, Tsuyoshi Okamura, Shuichi Awata, Yasuyuki Gondo, Yukie Masui, Hiroki Inagaki, Kei Kamide, Kazunori Ikebe, Yasumichi Arai, and Tatsuro Ishizaki
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Aged, 80 and over ,Risk Factors ,Nonagenarians ,Humans ,Risk Assessment - Published
- 2022
34. Usage of IT and Electronic Devices, and Its Structure, for Community-Dwelling Elderly.
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Madoka Ogawa, Hiroki Inagaki, and Yasuyuki Gondo
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- 2006
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35. Factors Predicting Tongue Pressure Decline among Community-Dwelling Older Adults: The Takashimadaira Study
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Chika Takahashi, Masanori Iwasaki, Keiko Motokawa, Yutaka Watanabe, Misato Hayakawa, Yurie Mikami, Maki Shirobe, Hiroki Inagaki, Ayako Edahiro, Yuki Ohara, Hirohiko Hirano, Shoji Shinkai, and Shuichi Awata
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Male ,Tongue ,epidemiology ,geriatrics ,longitudinal study ,oral health ,Health, Toxicology and Mutagenesis ,Public Health, Environmental and Occupational Health ,Pressure ,Humans ,Cognitive Dysfunction ,Female ,Independent Living ,Longitudinal Studies ,Aged - Abstract
A limited number of longitudinal studies have explored factors contributing to decreases in tongue pressure (TP). This longitudinal study aimed to clarify the factors affecting TP decline among community-dwelling older adults. We followed the Takashimadaira Study participants with a baseline TP ≥ 30 kPa for 2 years. A TP of
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- 2022
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36. A characteristic N-glycopeptide signature associated with diabetic cognitive impairment identified in a longitudinal cohort study
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Yuri Miura, Hiroki Tsumoto, Yukie Masui, Hiroki Inagaki, Madoka Ogawa, Yuta Ideno, Kyojiro Kawakami, Keitaro Umezawa, Mai Kabayama, Yuya Akagi, Hiroshi Akasaka, Koichi Yamamoto, Hiromi Rakugi, Tatsuro Ishizaki, Yasumichi Arai, Kazunori Ikebe, Kei Kamide, Yasuyuki Gondo, and Tamao Endo
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Biophysics ,Molecular Biology ,Biochemistry - Published
- 2023
37. Dietary variety is associated with sleep efficiency in urban-dwelling older adults: A longitudinal study
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Takahiro Yoshizaki, Maki Shirobe, Keiko Motokawa, Hirohiko Hirano, Yutaka Watanabe, Yuki Ohara, Misato Hayakawa, Tomohiro Yano, Shoji Shinkai, Hiroki Inagaki, Shuichi Awata, and Kaori Yamamoto
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0301 basic medicine ,Gerontology ,Longitudinal study ,Urban Population ,Endocrinology, Diabetes and Metabolism ,030209 endocrinology & metabolism ,03 medical and health sciences ,0302 clinical medicine ,Humans ,Medicine ,Longitudinal Studies ,Aged ,030109 nutrition & dietetics ,Nutrition and Dietetics ,Sleep quality ,business.industry ,Sleep in non-human animals ,Diet ,Cross-Sectional Studies ,Panel analysis ,Drinking Status ,Smoking status ,Geriatric Depression Scale ,Sleep ,business ,Body mass index - Abstract
Summary Background & aims Improving sleep quality is important for an aging society. However, no study has been conducted on the association between dietary variety and sleep efficiency among older Japanese adults using longitudinal data. The current study is a longitudinal study that aimed to elucidate the association between dietary variety and sleep efficiency in older Japanese adults. Methods This study was conducted among older adults (≥70 years old in 2016) in the metropolitan area of Tokyo, Japan, between 2016 and 2018. Dietary variety score (DVS) and sleep efficiency were determined for all participants and were used to assess dietary habits and sleep quality, respectively. A cross-lagged panel analysis was used to consider the prospective associations between DVS and sleep efficiency, and this analysis was performed before and after adjusting for possible covariates in the 2016 data. Results After adjusting for age, sex, body mass index, current drinking status, current smoking status, exercise habits, living (alone or with others) style, the Japanese version of the Geriatric Depression Scale (Short Form), sleep duration and retiring time the DVS in 2016 predicted the sleep efficiency in 2018 (β = 0.130, p Conclusion The possibility that DVS can predict sleep efficiency 2 years later was demonstrated.
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- 2021
38. The Psychometric Properties of the Montreal Cognitive Assessment (MoCA)
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Kazunori Ikebe, Yoshiko Ishioka, Takeshi Nakagawa, Kei Kamide, Yasumichi Arai, Yasuyuki Gondo, Tatsuro Ishizaki, Giovanni Sala, Hiroki Inagaki, and Yukie Masui
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050103 clinical psychology ,03 medical and health sciences ,0302 clinical medicine ,05 social sciences ,Montreal Cognitive Assessment ,0501 psychology and cognitive sciences ,Cognition ,Measurement invariance ,Psychology ,030217 neurology & neurosurgery ,General Psychology ,Test (assessment) ,Clinical psychology - Abstract
Abstract. The Montreal Cognitive Assessment (MoCA) is a test assessing global cognition in older adults which is often used by researchers and clinicians worldwide, although some of its psychometric properties have yet to be established. We focus on three fundamental aspects: the factorial structure of the MoCA, its general factor saturation, and the measurement invariance of the test. We administered the MoCA to a large sample of Japanese older adults clustered in three cohorts (69–71-year-olds, 79–81-year-olds, and 89–91-year-olds; N = 2,408). Our results show that the test has an overall stable hierarchical factorial structure with a general factor at its apex and satisfactory general-factor saturation. We also found measurement invariance across participants of different ages, educational levels, economic status, and sex. This comprehensive investigation thus supports the idea that the MoCA is a valid tool to assess global cognition in older adults of different socioeconomic status and age ranges.
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- 2020
39. [Comprehensive health assessment of community-dwelling older people using mail method and its association with future transition to need for long-term care and dementia]
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Hiroki, Inagaki, Mika, Sugiyama, Kae, Ito, Naoko, Sakuma, Chiaki, Ura, Fumiko, Miyamae, Tsuyoshi, Okamura, and Shuichi, Awata
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Activities of Daily Living ,Humans ,Dementia ,Independent Living ,Postal Service ,Long-Term Care ,Aged - Abstract
Objectives We selected assessment items that can be used to evaluate the physical, mental, and social functions of community-dwelling older people comprehensively and easily, and examined whether these items could predict a future transition to the requirement for nursing care and dementia.Methods We conducted a self-administered mail survey of 4,439 community-dwelling older people, who were not certified as requiring nursing care in 2011. The items for the survey were shortlisted out of a total of 54 items that were selected by referring to existing scales, and the evaluation items were determined by pass rate and factor analysis. The cut-off point of the total scores was estimated by ROC analysis using the certification of requiring long-term care (support level 1 or higher) and level of independence in the daily lives of older people with dementia (independence level I or higher) in 2014 as external criteria. The predictive validity was examined by binomial logistic regression analysis using the cut-off point of the total score and the score of the sub-domains as explanatory variables, and the requirement of nursing care and independence level of dementia in 2014 as objective variables.Results A factor analysis of 1,810 subjects with no deficiencies in the 54 items identified 24 items in five domains (mental health, walking function, Instrumental Activities of Daily Living (IADL), cognitive function, and social support). During the ROC analysis, the cut-off point of the total score was estimated to be 20/21 points (nursing care: AUC 0.75, sensitivity 0.77, specificity, 0.56; dementia: AUC 0.75; sensitivity 0.79, specificity 0.55). The binomial logistic regression analysis showed that persons with a total score of less than 20 points in 2011 were significantly more likely to be certified as requiring nursing care (odds ratio 2.57, 95%CI 1.69-3.92, P0.01) or show a decline in their independence level of dementia (odds ratio 3.12, 95%CI 1.83-5.32, P0.01) in 2014. The scores of mental health, walking function, and IADL were significantly associated with certification of requiring nursing care, while walking function and cognitive function were significantly associated with dementia.Conclusion We believe that the selected items in this study can successfully predict a transition to needing nursing care and dementia in the future. In the sub-domains, the results suggested an association with physical and mental function, as has been previously reported, but little association with social function.
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- 2022
40. Occlusal force is correlated with cognitive function directly as well as indirectly via food intake in community-dwelling older Japanese: From the SONIC study
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Kazunori, Ikebe, Yasuyuki, Gondo, Kei, Kamide, Yukie, Masui, Taturo, Ishizaki, Yasumichi, Arai, Hiroki, Inagaki, Takeshi, Nakagawa, Mai, Kabayama, Hirochika, Ryuno, Hitomi, Okubo, Hajime, Takeshita, Chisato, Inomata, Yuko, Kurushima, Yusuke, Mihara, Kohdai, Hatta, Motoyoshi, Fukutake, Kaori, Enoki, Taiji, Ogawa, Ken-Ichi, Matsuda, Ken, Sugimoto, Ryosuke, Oguro, Yoichi, Takami, Norihisa, Itoh, Yasushi, Takeya, Koichi, Yamamoto, Hiromi, Rakugi, Shinya, Murakami, Masahiro, Kitamura, Yoshinobu, Maeda, Kazunori, Ikebe, Yasuyuki, Gondo, Kei, Kamide, Yukie, Masui, Taturo, Ishizaki, Yasumichi, Arai, Hiroki, Inagaki, Takeshi, Nakagawa, Mai, Kabayama, Hirochika, Ryuno, Hitomi, Okubo, Hajime, Takeshita, Chisato, Inomata, Yuko, Kurushima, Yusuke, Mihara, Kohdai, Hatta, Motoyoshi, Fukutake, Kaori, Enoki, Taiji, Ogawa, Ken-Ichi, Matsuda, Ken, Sugimoto, Ryosuke, Oguro, Yoichi, Takami, Norihisa, Itoh, Yasushi, Takeya, Koichi, Yamamoto, Hiromi, Rakugi, Shinya, Murakami, Masahiro, Kitamura, and Yoshinobu, Maeda
- Abstract
source:Epub 2018 Jan 5, source:https://pubmed.ncbi.nlm.nih.gov/29304177, source:https://cir.nii.ac.jp/crid/1050282677476374400
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- 2022
41. Association between dietary patterns and cognitive function among 70-year-old Japanese elderly: a cross-sectional analysis of the SONIC study
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Hitomi, Okubo, Hiroki, Inagaki, Yasuyuki, Gondo, Kei, Kamide, Kazunori, Ikebe, Yukie, Masui, Yasumichi, Arai, Tatsuro, Ishizaki, Satoshi, Sasaki, Takeshi, Nakagawa, Mai, Kabayama, Ken, Sugimoto, Hiromi, Rakugi, Yoshinobu, Maeda, SONIC Study Group, Hitomi, Okubo, Hiroki, Inagaki, Yasuyuki, Gondo, Kei, Kamide, Kazunori, Ikebe, Yukie, Masui, Yasumichi, Arai, Tatsuro, Ishizaki, Satoshi, Sasaki, Takeshi, Nakagawa, Mai, Kabayama, Ken, Sugimoto, Hiromi, Rakugi, Yoshinobu, Maeda, and SONIC Study Group
- Abstract
source:Epub 2017 Sep 11, source:https://pubmed.ncbi.nlm.nih.gov/28893250
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- 2022
42. Association between heart diseases, social factors and physical frailty in community‐dwelling older populations: The septuagenarians, octogenarians, nonagenarians investigation with centenarians study
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Yasushi Takeya, Yuya Akagi, Ken Sugimoto, Kazunori Ikebe, Kei Kamide, Mai Kabayama, Tatsuro Ishizaki, Kayo Godai, Saori Yasumoto, Yasuyuki Gondo, Hiroshi Akasaka, Werayuth Srithumsuk, Hiroki Inagaki, Yoichi Takami, Yukie Masui, Madoka Ogawa, Koichi Yamamoto, Hiromi Rakugi, Nonglak Klinpudtan, and Eri Kiyoshige
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Male ,Gerontology ,Heart Diseases ,Heart disease ,Frail Elderly ,Poison control ,Physical examination ,Logistic regression ,Surveys and Questionnaires ,Injury prevention ,Odds Ratio ,Prevalence ,medicine ,Humans ,Interpersonal Relations ,Medical history ,Geriatric Assessment ,Aged ,Aged, 80 and over ,Frailty ,medicine.diagnostic_test ,business.industry ,Social Support ,Odds ratio ,medicine.disease ,Confidence interval ,Walking Speed ,Cross-Sectional Studies ,Female ,Independent Living ,business - Abstract
AIM Heart diseases and social factors are associated with physical frailty, but there are few studies of older people living in the community. Consequently, the aim of this study was to examine the association between heart diseases, social factors and physical frailty in community-dwelling older populations including the oldest-old people. METHODS The cross-sectional study included 1882 participants of community-dwelling older and oldest-old people. The survey site assessed questionnaires on medical history, social factors, blood samples and physical examination. Physical frailty was based on slow gait speed or weak grip strength. Associations were analyzed using multiple logistic regression with adjustments for covariate factors. RESULTS Subjects with heart disease had a higher prevalence of physical frailty than those without heart disease. After adjusting the covariate factors, heart diseases were associated with a slow gait speed (odds ratio [OR] = 1.62; 95% confidence interval [CI]: 1.13-2.32, P = 0.009). Frequency of going outdoors and direct interaction with relatives or friends were associated with a slow gait speed (OR = 0.83, 95% CI 0.75-0.91, P ≤ 0.001 and OR = 0.87, 95% CI 0.81-0.94, P
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- 2020
43. The association of blood pressure with physical frailty and cognitive function in community-dwelling septuagenarians, octogenarians, and nonagenarians: the SONIC study
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Yoichi Takami, Koichi Yamamoto, Ken Sugimoto, Hiroshi Akasaka, Yuya Akagi, Kazunori Ikebe, Hiroki Inagaki, Saori Yasumoto, Kayo Godai, Madoka Ogawa, Kei Kamide, Hirochika Ryuno, Yasushi Takeya, Yasuyuki Gondo, Takeshi Nakagawa, Hiromi Rakugi, Peter Martin, Mai Kabayama, Eri Kiyoshige, Yasumichi Arai, Tatsuro Ishizaki, and Yukie Masui
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Gerontology ,Physiology ,business.industry ,Regression analysis ,Cognition ,030204 cardiovascular system & hematology ,Gait speed ,03 medical and health sciences ,Grip strength ,0302 clinical medicine ,Blood pressure ,Older patients ,Internal Medicine ,Medicine ,030212 general & internal medicine ,Cardiology and Cardiovascular Medicine ,Association (psychology) ,business ,Antihypertensive medication - Abstract
We investigated the association of systolic blood pressure (SBP) level with physical frailty and cognitive function in community-dwelling older Japanese. Using the ‘Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians’ survey as the baseline, we performed a cross-sectional analysis of people aged 70 ± 1 (n = 1000), 80 ± 1 (n = 978), and 90 ± 1 (n = 272) years. Medical histories and medications were collected via interviews conducted by medical professionals. Blood pressure (BP), grip strength, gait speed, and cognitive function were examined on site. Trend analysis and multiple regression analysis were used to determine the association of the SBP level with physical frailty and cognitive function. The principal finding was that the association of SBP with physical frailty and cognitive function varied depending on characteristics such as age, physical and cognitive function, and antihypertensive medication use. A lower SBP level was associated with a higher prevalence of physical frailty only among 80-year-olds who were on antihypertensive medication. A significant association was found between higher SBP and lower cognitive function among 70-year-olds, while among 90-year-olds, the opposite was found. No association was found among participants who were 80 years old or among participants of all ages without antihypertensive medication. Our finding that an inverted association between SBP and geriatric syndrome exists suggests that the treatment of older patients must be individualized to prevent geriatric syndrome.
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- 2020
44. Characteristics of detected and undetected dementia among community‐dwelling older people in Metropolitan Tokyo
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Tsuyoshi Okamura, Akira Hatakeyama, Hiroki Inagaki, Naoko Sakuma, Fumiko Miyamae, Hirotoshi Niikawa, Chiaki Ura, Ayako Edahiro, Takahiro Suzuki, Mika Sugiyama, Ko Furuta, Michiko Konno, Madoka Ogawa, Fumiko Ogisawa, and Shuichi Awata
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Male ,Gerontology ,Clinical Dementia Rating ,Medical care ,Social support ,Surveys and Questionnaires ,mental disorders ,medicine ,Humans ,Dementia ,Cognitive Dysfunction ,Dementia diagnosis ,Tokyo ,Geriatric Assessment ,Aged ,Aged, 80 and over ,Frailty ,business.industry ,Social Support ,Physical health ,Mental Status and Dementia Tests ,medicine.disease ,Metropolitan area ,Early Diagnosis ,Female ,Independent Living ,Older people ,business - Abstract
AIM Although a series of policies have been adapted to deliver an early diagnosis of dementia, many people living with dementia remain undetected and undiagnosed. The aim of this study is to investigate the characteristics of undetected dementia in community-dwelling older people in Metropolitan Tokyo. METHODS We conducted a three-step survey. First, the questionnaires were mailed, in total, to 7614 residents aged ≥70 years in one area in Tokyo, and 5430 were retrieved. Secondly, 2020 individuals attended the face-to-face survey, including Mini-Mental State Exam (MMSE). Thirdly, 198 of 335 individuals who scored
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- 2020
45. Cross-sectional study of age-specific differences in salivary occult blood test results in older adults
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Shuichi Awata, Keiko Motokawa, Junichi Furuya, Maki Shirobe, Ayako Edahiro, Chiaki Matsubara, Yutaka Watanabe, Shunsuke Minakuchi, Shoji Shinkai, Yuki Ohara, Junko Nakajima, Hiroki Inagaki, Michiyo Obana, and Hirohiko Hirano
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medicine.medical_specialty ,Saliva ,business.industry ,Cross-sectional study ,Binomial regression ,Smoking ,Oral Health ,Odds ratio ,Oral health ,Dental plaque ,medicine.disease ,Occult ,Age specific ,stomatognathic diseases ,Cross-Sectional Studies ,Occult Blood ,Surveys and Questionnaires ,Internal medicine ,Medicine ,business ,General Dentistry - Abstract
This study aimed to identify factors associated with poor oral health status, as indicated by salivary occult blood (SOB) level, in community-dwelling older adults. A total of 592 community-dwelling participants aged 70 to 84 years with 20 to 28 teeth participated in the survey and SOB evaluation. Survey items included behaviors during dental visits, systemic diseases, smoking habit, cognitive function, and findings of intraoral examination. To identify factors associated with high SOB levels, binomial logistic regression analysis was performed after classifying participants as having high and low SOB on the basis of 75th-percentile SOB measurements. Presence of dental plaque (odds ratio [OR]: 2.26), poor subjective oral health (OR: 2.99) (for the age group 70 to 74 years), fewer remaining teeth (OR: 0.80), no dental visits during the previous year (OR: 2.80) (for the age group 75 to 79 years), and no dental visits during the previous year (OR: 3.93) (for the age group 80 to 84 years) were significantly associated with high SOB levels. The factors associated with high SOB, which indicates poor oral health status, differed by age group in community-dwelling older adults. Therefore, oral health management may improve oral health by providing different age groups with care that accounts for their physical and social functional abilities.
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- 2020
46. Factors associated with inability to attend a follow-up assessment, mortality, and institutionalization among community-dwelling older people with cognitive impairment during a 5-year period: evidence from community-based participatory research
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Tsuyoshi Okamura, Chiaki Ura, Mika Sugiyama, Hiroki Inagaki, Fumiko Miyamae, Ayako Edahiro, Tsutomu Taga, Shuji Tsuda, Riko Nakayama, Kae Ito, and Shuichi Awata
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Psychiatry and Mental health ,Community-Based Participatory Research ,Humans ,Institutionalization ,Cognitive Dysfunction ,Dementia ,Independent Living ,Geriatrics and Gerontology ,Gerontology ,Aged ,Follow-Up Studies - Abstract
The aim of the present study was to explore factors associated with (i) the inability to attend a follow-up assessment in the community-based participatory research (CBPR) framework; (ii) mortality; and (iii) institutionalization, across a 5-year period among older people with cognitive impairment identified via an epidemiological survey.The participants were 198 older people whose score on the Mini-Mental State Examination was below 24, and who were living in our CBPR region in the Tokyo metropolitan area. Baseline data included sociodemographic factors, health-related factors, social factors, and assessments by healthcare professionals. Over the following 5 years we observed what happened to the subjects within the CBPR framework. Bivariate and stepwise multiple logistic regression analyses were performed to explore the factors associated with the inability to attend a follow-up assessment, 5-year mortality, and institutionalization.Participants who did not attend a follow-up assessment tended to live alone. Being older (80), living with others, frailty, and the need for rights protection and daily living support were associated with increased mortality. Long-term care insurance certification was strongly associated with institutionalization as a natural consequence of the health-care system. Having dementia and low access to doctors were also positively associated with institutionalization.Older people with cognitive impairment who are living alone are at higher risk of being overlooked by society. To move toward more inclusive communities, the following are recommended: (i) more interventions focusing on older people living alone; (ii) social interventions to detect daily life collapse or rights violations; and (iii) more support to help people with dementia continue living in the community.
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- 2022
47. Normative Data of the Trail Making Test Among Urban Community-Dwelling Older Adults in Japan
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Hiroyuki Suzuki, Naoko Sakuma, Momoko Kobayashi, Susumu Ogawa, Hiroki Inagaki, Ayako Edahiro, Chiaki Ura, Mika Sugiyama, Fumiko Miyamae, Yutaka Watanabe, Shoji Shinkai, and Shuichi Awata
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Aging ,Cognitive Neuroscience - Abstract
IntroductionPopulation aging is likely to increase the number of people with dementia living in urban areas. The Trail Making Test (TMT) is widely used as a cognitive task to measure attention and executive function among older adults. Normative data from a sample of community-dwelling older adults are required to evaluate the executive function of this population. The purpose of this study was to examine the Trail Making Test completion rate and completion time among urban community-dwelling older adults in Japan.MethodsA survey was conducted at a local venue or during a home visit (n = 1,966). Cognitive tests were conducted as a part of the survey, and TMT Parts A (TMT-A) and B (TMT-B) were completed after the completion of the Japanese version of the Mini-Mental State Examination (MMSE-J). Testers recorded TMT completion status, completion time, and the number of errors observed.ResultsIn the TMT-A, 1,913 (99.5%) participants understood the instructions, and 1,904 (99.1%) participants completed the task within the time limit of 240 s. In the TMT-B, 1,839 (95.9%) participants understood the instructions, and 1,584 (82.6%) participants completed the task within the time limit of 300 s. The completion rate of TMT-B was 90.2 and 41.8% for participants with an MMSE-J score of >23 points and ≦23 points, respectively. Results of multiple regression analyses showed that age, education, and the MMSE-J score were associated with completion time in both TMTs.ConclusionIn both TMTs, completion time was associated with age, education, and general cognitive function. However, not all participants completed the TMT-B, and the completion rate was relatively low among participants with low MMSE-J scores. These findings may help interpret future TMT assessments.
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- 2021
48. A Two-Year Longitudinal Study of the Association between Oral Frailty and Deteriorating Nutritional Status among Community-Dwelling Older Adults
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Hirohiko Hirano, Yuki Ohara, Keiko Motokawa, Shoji Shinkai, Masanori Iwasaki, Ayako Edahiro, Yutaka Watanabe, Shuichi Awata, Maki Shirobe, and Hiroki Inagaki
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Male ,Gerontology ,Longitudinal study ,medicine.medical_specialty ,Health, Toxicology and Mutagenesis ,lcsh:Medicine ,Logistic regression ,Article ,03 medical and health sciences ,0302 clinical medicine ,Epidemiology ,Pressure ,medicine ,Humans ,Longitudinal Studies ,030212 general & internal medicine ,Geriatric Assessment ,Aged ,Geriatrics ,geriatrics ,Frailty ,business.industry ,Incidence (epidemiology) ,Confounding ,lcsh:R ,Public Health, Environmental and Occupational Health ,longitudinal study ,030206 dentistry ,Odds ratio ,nutritional status ,stomatognathic diseases ,Cross-Sectional Studies ,Population study ,oral health ,Female ,epidemiology ,Independent Living ,Mouth Diseases ,business - Abstract
Background: Limited longitudinal studies exist to evaluate whether poor oral health and functions affect the incidence of deteriorating nutritional status. We investigated if there were longitudinal associations between oral frailty, defined as accumulated deficits in oral health, and deteriorating nutritional status among community-dwelling older adults. Methods: The study population consisted of 191 men and 275 women (mean age, 76.4 years) from the Takashimadaira Study. Multifaced oral health assessment was performed at baseline, and oral frailty was defined as having &ge, 3 of the following six components: fewer teeth, low masticatory performance, low articulatory oral motor skill, low tongue pressure, and difficulties in chewing and swallowing. Nutritional status assessment was performed at baseline and two-year follow-up using the Mini Nutritional Assessment®, Short Form (MNA®, SF). Deteriorating nutritional status was defined as a decline in the nutritional status categories based on the MNA®, SF score during the study period. The association between oral frailty and deteriorating nutritional status was assessed using logistic regression analyses. Results: Oral frailty was observed in 67 (14.4%) participants at baseline. During the study, 58 (12.4%) participants exhibited deteriorating nutritional status. After adjusting for potential confounders, oral frailty was significantly associated with deteriorating nutritional status (adjusted odds ratio, 2.24, 95% confidence interval, 1.08&ndash, 4.63). Conclusion: Community-dwelling older adults with oral frailty had an increased risk of deteriorating nutritional status.
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- 2021
49. Barrier to sharing a dementia diagnosis with neighbors in Tokyo.
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Tsuyoshi Okamura, Tsutomu Taga, Hiroki Inagaki, Fumiko Miyamae, Chiaki Ura, Mika Sugiyama, Ayako Edahiro, Maki Shirobe, Keiko Motokawa, Narumi Kojima, Yosuke Osuka, Masanori Iwasaki, Hiroyuki Sasai, Hirohiko Hirano, and Shuichi Awata
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DIAGNOSIS of dementia ,DISCLOSURE ,WELL-being ,CONFIDENCE intervals ,MULTIPLE regression analysis ,AGE distribution ,MENTAL health ,ATTITUDES toward illness ,SEX distribution ,INDEPENDENT living ,INTERPERSONAL relations ,ACTION research ,QUESTIONNAIRES ,DESCRIPTIVE statistics ,CHI-squared test ,LOGISTIC regression analysis ,ODDS ratio ,RESIDENTIAL patterns ,NEIGHBORHOOD characteristics ,TRUST ,OLD age - Abstract
The article focuses on community-based participatory research conducted in Tokyo, regarding the disclosure of dementia diagnoses among older residents. It explores factors influencing the sharing of a dementia diagnosis with neighbors and emphasizes the importance of such disclosure for receiving support. It highlight gender differences, indicating that being male, lack of trust in neighbors, and living in a separate house are associated with a reluctance to share dementia diagnoses.
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- 2023
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50. Nutritional status and body composition in cognitively impaired older persons living alone: The Takashimadaira study
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Shuichi Awata, Maki Shirobe, Ayako Edahiro, Misato Hayakawa, Yuki Ohara, Shoji Shinkai, Keiko Motokawa, Hiroki Inagaki, Masanori Iwasaki, Yurie Mikami, Hirohiko Hirano, and Yutaka Watanabe
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Male ,Physiology ,Logistic regression ,Biochemistry ,Geographical Locations ,Elderly ,Japan ,Medicine and Health Sciences ,Medicine ,Mass index ,Cognitive Impairment ,Aged, 80 and over ,Multidisciplinary ,biology ,Cognitive Neurology ,Ingestion ,Confounding ,Age Factors ,Neurology ,Body Composition ,Female ,Independent Living ,Research Article ,medicine.medical_specialty ,Asia ,Science ,Cognitive Neuroscience ,Serum albumin ,Nutritional Status ,Internal medicine ,Albumins ,Adults ,Humans ,Cognitive Dysfunction ,Serum Albumin ,Nutrition ,Aged ,Marital Status ,business.industry ,Malnutrition ,Biology and Life Sciences ,Proteins ,Odds ratio ,Anthropometry ,Swallowing ,medicine.disease ,Long-Term Care ,Confidence interval ,Health Care ,Cross-Sectional Studies ,Age Groups ,People and Places ,biology.protein ,Cognitive Science ,Population Groupings ,business ,Physiological Processes ,Neuroscience - Abstract
Objectives To investigate nutritional status and body composition in cognitively impaired older persons living alone. Methods This cross-sectional study included 1051 older adults (633 women and 418 men, mean age: 77.1 years) from the Takashimadaira study. The study participants were categorized according to whether they lived alone, which was confirmed via questionnaire, and had cognitive impairment, which was defined as having a Mini Mental State Examination-Japanese score ≤23. Nutritional status was evaluated using the serum albumin level. The fat-free mass index (FFMI) was calculated based on anthropometric and body composition measurements. A logistic regression model with the outcome of a low serum albumin level (serum albumin 2 in men and 2 in women) were used to analyze the data. Results The percentages of participants in the living alone (-)/cognitive impairment (-) group, the living alone (+)/cognitive impairment (-) group, the living alone (-)/cognitive impairment (+) group, and the living alone (+)/cognitive impairment (+) group were 54.8%, 37.3%, 5.6%, and 2.3%, respectively. Compared to the living alone (-)/cognitive impairment (-) group, the living alone (+)/cognitive impairment (+) group was more likely to have a low serum albumin level (adjusted odds ratio = 3.10, 95% confidence interval = 1.31 to 7.33) and low FFMI (adjusted odds ratio = 2.79, 95% confidence interval = 1.10 to 7.06) after adjusting for potential confounders. Conclusion Cognitively impaired older adults living alone had poorer nutrition than cognitively normal and cohabitating persons in this study. Our results highlight the importance of paying extra attention to nutritional status for this group of community-dwelling older adults.
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- 2021
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