Back to Search
Start Over
Overlap Between Apolipoprotein Eε4 Allele and Slowing Gait Results in Cognitive Impairment
- Source :
- Frontiers in Aging Neuroscience, Vol 11 (2019)
- Publication Year :
- 2019
- Publisher :
- Frontiers Media S.A., 2019.
-
Abstract
- Background: Although apolipoprotein E polymorphism ε4 allele (ApoE4) and slow gait are well-known risk factors for cognitive impairment, examination of their combined effect on cognitive function is lacking. Our objective was to elucidate whether a combination of ApoE4 phenotyping and slow gait resulted in greater cognitive impairment.Methods: Overall, 1,085 community-dwelling older adults, either ApoE4 carriers (n = 167, 15.4%) or non-ApoE4 carriers, were included from the “Takashimadaira study.” Gait speed was assessed with an electronic walkway and slow gait was defined as
Details
- Language :
- English
- ISSN :
- 16634365
- Volume :
- 11
- Database :
- Directory of Open Access Journals
- Journal :
- Frontiers in Aging Neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.9ed7d8a86046699aa5d15f65a87c11
- Document Type :
- article
- Full Text :
- https://doi.org/10.3389/fnagi.2019.00247