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107 results on '"Garcia, Nadia"'

1. MROS: A framework for robot self-adaptation

Author

Silva, Gustavo Rezende, Bozhinoski, Darko, Oviedo, Mario Garzon, Montero, Mariano Ramírez, Garcia, Nadia Hammoudeh, Deshpande, Harshavardhan, Wasowski, Andrzej, and Corbato, Carlos Hernandez

Subjects
Computer Science - Robotics
Abstract

Self-adaptation can be used in robotics to increase system robustness and reliability. This work describes the Metacontrol method for self-adaptation in robotics. Particularly, it details how the MROS (Metacontrol for ROS Systems) framework implements and packages Metacontrol, and it demonstrate how MROS can be applied in a navigation scenario where a mobile robot navigates in a factory floor. Video: https://www.youtube.com/watch?v=ISe9aMskJuE, Comment: 5 pages, 4 figures, accepted at ICSE 2023 demo track

Published
2023

2. Effects of COVID-19 mRNA vaccination on HIV viremia and reservoir size

Author

Duncan, Maggie C., Omondi, F. Harrison, Kinloch, Natalie N., Lapointe, Hope R., Speckmaier, Sarah, Moran-Garcia, Nadia, Lawson, Tanya, DeMarco, Mari L., Simons, Janet, Holmes, Daniel T., Lowe, Christopher F., Bacani, Nic, Sereda, Paul, Barrios, Rolando, Harris, Marianne, Romney, Marc G., Montaner, Julio S.G., Brumme, Chanson J., Brockman, Mark A., and Brumme, Zabrina L.

Published
2024
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3. MROS: Runtime Adaptation For Robot Control Architectures

Author

Bozhinoski, Darko, Corbato, Carlos Hernandez, Oviedo, Mario Garzon, van der Hoorn, Gijs, Garcia, Nadia Hammoudeh, Deshpande, Harshavardhan, Tjerngren, Jon, and Wasowski, Andrzej

Subjects
Computer Science - Robotics, Computer Science - Software Engineering
Abstract

Known attempts to build autonomous robots rely on complex control architectures, often implemented with the Robot Operating System platform (ROS). Runtime adaptation is needed in these systems, to cope with component failures and with contingencies arising from dynamic environments-otherwise, these affect the reliability and quality of the mission execution. Existing proposals on how to build self-adaptive systems in robotics usually require a major re-design of the control architecture and rely on complex tools unfamiliar to the robotics community. Moreover, they are hard to reuse across applications. This paper presents MROS: a model-based framework for run-time adaptation of robot control architectures based on ROS. MROS uses a combination of domain-specific languages to model architectural variants and captures mission quality concerns, and an ontology-based implementation of the MAPE-K and meta-control visions for run-time adaptation. The experiment results obtained applying MROS in two realistic ROS-based robotic demonstrators show the benefits of our approach in terms of the quality of the mission execution, and MROS' extensibility and re-usability across robotic applications.

Published
2020

4. T-Cell Responses to COVID-19 Vaccines and Breakthrough Infection in People Living with HIV Receiving Antiretroviral Therapy

Author

Datwani, Sneha, primary, Kalikawe, Rebecca, additional, Waterworth, Rachel, additional, Mwimanzi, Francis M., additional, Liang, Richard, additional, Sang, Yurou, additional, Lapointe, Hope R., additional, Cheung, Peter K., additional, Omondi, Fredrick Harrison, additional, Duncan, Maggie C., additional, Barad, Evan, additional, Speckmaier, Sarah, additional, Moran-Garcia, Nadia, additional, DeMarco, Mari L., additional, Hedgcock, Malcolm, additional, Costiniuk, Cecilia T., additional, Hull, Mark, additional, Harris, Marianne, additional, Romney, Marc G., additional, Montaner, Julio S. G., additional, Brumme, Zabrina L., additional, and Brockman, Mark A., additional

Published
2024
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5. Antibody response durability following three-dose coronavirus disease 2019 vaccination in people with HIV receiving suppressive antiretroviral therapy

Author

Lapointe, Hope R., Mwimanzi, Francis, Cheung, Peter K., Sang, Yurou, Yaseen, Fatima, Speckmaier, Sarah, Barad, Evan, Moran-Garcia, Nadia, Datwani, Sneha, Duncan, Maggie C., Kalikawe, Rebecca, Ennis, Siobhan, Young, Landon, Ganase, Bruce, Omondi, F. Harrison, Umviligihozo, Gisele, Dong, Winnie, Toy, Junine, Sereda, Paul, Burns, Laura, Costiniuk, Cecilia T., Cooper, Curtis, Anis, Aslam H., Leung, Victor, Holmes, Daniel, DeMarco, Mari L., Simons, Janet, Hedgcock, Malcolm, Prystajecky, Natalie, Lowe, Christopher F., Romney, Marc G., Barrios, Rolando, Guillemi, Silvia, Brumme, Chanson J., Montaner, Julio S.G., Hull, Mark, Harris, Marianne, Niikura, Masahiro, Brockman, Mark A., and Brumme, Zabrina L.

Published
2023
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7. Humoral immune responses to COVID-19 vaccination in people living with HIV receiving suppressive antiretroviral therapy

Author

Brumme, Zabrina L., Mwimanzi, Francis, Lapointe, Hope R., Cheung, Peter K., Sang, Yurou, Duncan, Maggie C., Yaseen, Fatima, Agafitei, Olga, Ennis, Siobhan, Ng, Kurtis, Basra, Simran, Lim, Li Yi, Kalikawe, Rebecca, Speckmaier, Sarah, Moran-Garcia, Nadia, Young, Landon, Ali, Hesham, Ganase, Bruce, Umviligihozo, Gisele, Harrison Omondi, F., Atkinson, Kieran, Sudderuddin, Hanwei, Toy, Junine, Sereda, Paul, Burns, Laura, Costiniuk, Cecilia T., Cooper, Curtis, Anis, Aslam H., Leung, Victor, Holmes, Daniel, DeMarco, Mari L., Simons, Janet, Hedgcock, Malcolm, Romney, Marc G., Barrios, Rolando, Guillemi, Silvia, Brumme, Chanson J., Pantophlet, Ralph, Montaner, Julio S. G., Niikura, Masahiro, Harris, Marianne, Hull, Mark, and Brockman, Mark A.

Published
2022
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8. SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8+ T-cells

Author

Stevenson, Eva M., Terry, Sandra, Copertino, Dennis, Leyre, Louise, Danesh, Ali, Weiler, Jared, Ward, Adam R., Khadka, Pragya, McNeil, Evan, Bernard, Kevin, Miller, Itzayana G., Ellsworth, Grant B., Johnston, Carrie D., Finkelsztein, Eli J., Zumbo, Paul, Betel, Doron, Dündar, Friederike, Duncan, Maggie C., Lapointe, Hope R., Speckmaier, Sarah, Moran-Garcia, Nadia, Papa, Michelle Premazzi, Nicholes, Samuel, Stover, Carissa J., Lynch, Rebecca M., Caskey, Marina, Gaebler, Christian, Chun, Tae-Wook, Bosque, Alberto, Wilkin, Timothy J., Lee, Guinevere Q., Brumme, Zabrina L., and Jones, R. Brad

Published
2022
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9. High-titre methylene blue-treated convalescent plasma as an early treatment for outpatients with COVID-19: a randomised, placebo-controlled trial

Author

Ferrer, Susana, Gallardo, Mireia, Ubals, Maria, González-Beiras, Camila, Vall-Mayans, Martí, Suñer, Clara, Laporte-Villar, Clàudia, Nieto, Aroa, Comas-Leon, Xavier, Jiménez, Zahida, Ramírez-Viaplana, Ferran, Delgado-Capel, Maria, Díez Sánchez, Beatriz, Pons Barber, Maria, Gonzalez Ruiz, Cristian, Navarrete Gonzalez, Laura, González García, David, Vivero Larraza, Ainhoa, Carceles Peiró, Victor, Roquer López, Clàudia, Robert, Neus, Palet, Carles, Gudiol, Carlota, Casares Gonzalez, Pablo, Arcos Vila, Gemma, Flores Aguilera, Begoña, Rodríguez-Sevilla, Graciela, Dastis Arias, Macarena, Roca Font, Judit, Carrasco Matos, Katherine M., Saüch Valmaña, Glòria, Vidal Obradors, Carla, Tarres García, Silvia, Curriu Sabatès, Margarida, Nieto Rodríguez, Raquel, Línio, Rosa, Fornos, Míriam, Casamitjana, Natàlia, Alonso, Eva, Martínez, Núria, Maglio, Laura Analía, Comellas Fernandez, Laura, Garcia, Nadia, Hernández, Luis, González, Maria Isabel, Bravo, Anna, García, Yolanda, Sauleda Oliveras, Silvia, Vertiz, Tatiana, Benavent, Sergio, Bianco, Andrea Sofia, Verdaguer, Joaquim, Briones Zambrano, Ney Nicanor, Viozquez Meya, Maria, Hernández, Águeda, Casaña Lopez, Cristina, Bordoy, Antoni E., González Soler, Victoria, Giménez, Montserrat, París, Alexa, Marfil, Silvia, Trinité, Benjamin, Grau, Eulàlia, Alemany, Andrea, Millat-Martinez, Pere, Corbacho-Monné, Marc, Malchair, Pierre, Ouchi, Dan, Ruiz-Comellas, Anna, Ramírez-Morros, Anna, Rodríguez Codina, Joana, Amado Simon, Rosa, Videla, Sebastian, Costes, Gèlia, Capdevila-Jáuregui, Mar, Torrano-Soler, Pamela, San José, Alba, Bonet Papell, Glòria, Puig, Jordi, Otero, Aurema, Ruibal Suarez, Jose Carlos, Zarauza Pellejero, Alvaro, Llopis Roca, Ferran, Rodriguez Cortez, Orlando, Garcia Garcia, Vanesa, Vidal-Alaball, Josep, Millan, Anna, Contreras, Enric, Grifols, Joan-Ramon, Ancochea, Àgueda, Galvan-Femenia, Ivan, Piccolo Ferreira, Francini, Bonet, Mireia, Cantoni, Jordi, Prat, Núria, Ara, Jordi, Forcada Arcarons, Anna, Farré, Magí, Pradenas, Edwards, Blanco, Julià, Àngel Rodriguez-Arias, Miquel, Fernández Rivas, Gema, Marks, Michael, Bassat, Quique, Blanco, Ignacio, Baro, Bàrbara, Clotet, Bonaventura, and Mitjà, Oriol

Published
2022
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10. New alternatives to holder pasteurization in processing donor milk in human milk banks.

Author

Moro, Guido E., Girard, Melissa, Peila, Chiara, Garcia, Nadia, Escuder-Vieco, Diana, Keller, Kristin, Cassidy, Tanya, Bertino, Enrico, Boquien, Clair-Yves, Buffin, Rachel, Calvo, Javier, Gaya, Antoni, Gebauer, Corinna, Lamireau, Delphine, Lembo, David, Picaud, Jean-Charles, Wesolowska, Aleksandra, Arslanoglu, Sertac, Cavallarin, Laura, and Giribaldi, Marzia

Published
2024
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11. Effects of COVID-19 mRNA vaccination on HIV viremia and reservoir size

Author

Duncan, Maggie C., primary, Omondi, F. Harrison, additional, Kinloch, Natalie N., additional, Lapointe, Hope R., additional, Speckmaier, Sarah, additional, Moran-Garcia, Nadia, additional, Lawson, Tanya, additional, DeMarco, Mari L., additional, Simons, Janet, additional, Holmes, Daniel T., additional, Lowe, Christopher F., additional, Bacani, Nic, additional, Sereda, Paul, additional, Barrios, Rolando, additional, Harris, Marianne, additional, Romney, Marc G., additional, Montaner, Julio S.G., additional, Brumme, Chanson J., additional, Brockman, Mark A., additional, and Brumme, Zabrina L., additional

Published
2023
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14. MROS: A framework for robot self-adaptation

Author

Rezende Silva, G. (author), Garcia, Nadia Hammoudeh (author), Bozhinoski, D. (author), Deshpande, Harshavardhan (author), Garzon Oviedo, M.A. (author), Wasowski, Andrzej (author), Montero, Mariano Ramirez (author), Hernández, Carlos (author), Rezende Silva, G. (author), Garcia, Nadia Hammoudeh (author), Bozhinoski, D. (author), Deshpande, Harshavardhan (author), Garzon Oviedo, M.A. (author), Wasowski, Andrzej (author), Montero, Mariano Ramirez (author), and Hernández, Carlos (author)

Abstract

Self-adaptation can be used in robotics to increase system robust- ness and reliability. This work describes the Metacontrol method for self-adaptation in robotics. Particularly, it details how the MROS (Metacontrol for ROS Systems) framework implements and pack- ages Metacontrol, and it demonstrate how MROS can be applied in a navigation scenario where a mobile robot navigates in a factory floor. Video: https://www.youtube.com/watchvISe9aMskJuE, Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public., Robot Dynamics, Intelligent Vehicles

Published
2023
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17. Antibody response durability following three-dose COVID-19 vaccination in people with HIV receiving suppressive ART

Author

Lapointe, Hope R., primary, Mwimanzi, Francis, additional, Cheung, Peter K., additional, Sang, Yurou, additional, Yaseen, Fatima, additional, Speckmaier, Sarah, additional, Barad, Evan, additional, Moran-Garcia, Nadia, additional, Datwani, Sneha, additional, Duncan, Maggie C., additional, Kalikawe, Rebecca, additional, Ennis, Siobhan, additional, Young, Landon, additional, Ganase, Bruce, additional, Omondi, F. Harrison, additional, Umviligihozo, Gisele, additional, Dong, Winnie, additional, Toy, Junine, additional, Sereda, Paul, additional, Burns, Laura, additional, Costiniuk, Cecilia T., additional, Cooper, Curtis, additional, Anis, Aslam H., additional, Leung, Victor, additional, Holmes, Daniel, additional, Demarco, Mari L., additional, Simons, Janet, additional, Hedgcock, Malcolm, additional, Prystajecky, Natalie, additional, Lowe, Christopher F., additional, Romney, Marc G., additional, Barrios, Rolando, additional, Guillemi, Silvia, additional, Brumme, Chanson J., additional, Montaner, Julio S.G., additional, Hull, Mark, additional, Harris, Marianne, additional, Niikura, Masahiro, additional, Brockman, Mark A., additional, and Brumme, Zabrina L., additional

Published
2022
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19. People With Human Immunodeficiency Virus Receiving Suppressive Antiretroviral Therapy Show Typical Antibody Durability After Dual Coronavirus Disease 2019 Vaccination and Strong Third Dose Responses.

Author

Lapointe, Hope R, Mwimanzi, Francis, Cheung, Peter K, Sang, Yurou, Yaseen, Fatima, Umviligihozo, Gisele, Kalikawe, Rebecca, Speckmaier, Sarah, Moran-Garcia, Nadia, Datwani, Sneha, Duncan, Maggie C, Agafitei, Olga, Ennis, Siobhan, Young, Landon, Ali, Hesham, Ganase, Bruce, Omondi, F Harrison, Dong, Winnie, Toy, Junine, and Sereda, Paul

Subjects
SARS-CoV-2, COVID-19, HIV, ANTIRETROVIRAL agents, CORONAVIRUS diseases, VACCINATION
Abstract

Background Longer-term humoral responses to 2-dose coronavirus disease 2019 (COVID-19) vaccines remain incompletely characterized in people living with human immunodeficiency virus (HIV) (PLWH), as do initial responses to a third dose. Methods We measured antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein receptor-binding domain, angiotensin-converting enzyme 2 (ACE2) displacement, and viral neutralization against wild-type and Omicron strains up to 6 months after 2-dose vaccination, and 1 month after the third dose, in 99 PLWH receiving suppressive antiretroviral therapy and 152 controls. Results Although humoral responses naturally decline after 2-dose vaccination, we found no evidence of lower antibody concentrations or faster rates of antibody decline in PLWH compared with controls after accounting for sociodemographic, health, and vaccine-related factors. We also found no evidence of poorer viral neutralization in PLWH after 2 doses, nor evidence that a low nadir CD4+ T-cell count compromised responses. Post–third-dose humoral responses substantially exceeded post–second-dose levels, though Omicron-specific responses were consistently weaker than responses against wild-type virus. Nevertheless, post–third-dose responses in PLWH were comparable to or higher than controls. An mRNA-1273 third dose was the strongest consistent correlate of higher post–third-dose responses. Conclusion PLWH receiving suppressive antiretroviral therapy mount strong antibody responses after 2- and 3-dose COVID-19 vaccination. Results underscore the immune benefits of third doses in light of Omicron. [ABSTRACT FROM AUTHOR]

Published
2023
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20. Experience of minimally invasive surgery in neonates with congenital malformations in a tertiary care pediatric hospital

Author

García, Heladia, Licona-Islas, Carmen, Lopez-Garcia, Nadia, Cabello, HéCtor, and Galvan-Sosa, Vladimir

Subjects
Mortality, Surgery -- Health aspects, Children's hospitals -- Health aspects, Birth defects -- Health aspects, Newborn infants -- Health aspects, Pediatrics -- Health aspects, Genetic disorders -- Health aspects, Health
Abstract

Byline: Heladia. García, Carmen. Licona-Islas, Nadia. Lopez-Garcia, Héctor. Cabello, Vladimir. Galvan-Sosa Aim: The aim of this study is to report the experience with minimally invasive surgery (MIS) in neonates with [...]

Published
2020

21. Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients

Author

Rokx, Casper, Lammers, Jolanda, Buitenhuis, Lonneke, Postma, Douwe, Koster, David, Lukens, Michaèl, Scholtens, Thea, Boomgaard, Maartje van den, Kampschreur, Linda, Ubals, Maria, Prat, Núria, Díez Sánchez, Beatriz, Vértiz Guidotti, Thatiana, Pons Barber, Maria, Gonzalez Ruiz, Cristian, Navarrete Gonzalez, Laura, Ancochea, Àgueda, Ferrer, Magí, Videla, Sebas, Gudiol, Carlota, Fernández Rivas, Gema, CoV-Early Study Group, Vonderen, Marit van, Bianco, Andrea Sofia, Bravo, Anna, Otero, Aurema, Ruibal Suarez, Jose Carlos, Benavent, Sergio, Zarauza Pellejero, Alvaro, Línio, Rosa, Malchair, Pierre, Llopis Roca, Ferran, Blanco, Julian, Rodriguez Cortez, Orlando, Casares Gonzalez, Pablo, Arcos Vila, Gemma, García, Yolanda, Roca Font, Judit, Carrasco Matos, Katherine M., Saüch Valmaña, Glòria, Vidal Obradors, Carla, Koopmans, Marion, Ara, Jordi, COnV-ert Study Group, Rodríguez Codina, Joana, Tarres García, Silvia, Blanco, Ignacio, Hernández, Águeda, González Soler, Victoria, Curriu Sabatès, Margarida, Nieto Rodríguez, Raquel, Grífols, Joan Ramon, Briones Zambrano, Ney Nicanor, Millan, Anna, Capdevila Jáuregui, Mar, Fornos, Miriam, Casamitjana, Natàlia, Bordoy, Antoni E., Alonso, Eva, Zwet, Erik van, Miedema, Jelle, Martinez, Núria, Ramírez Morros, Anna, Bogers, Susanne, Maglio, Laura Analía, Amado Simon, Rosa, Comellas Fernandez, Laura, Garcia, Nadia, Ruiz Comellas, Anna, Baro, Bàrbara, Hernández, Luis, Viozquez Meya, Maria, Costes, Gèlia, Pradenas, Edwars, Forcada, Anna, Ginneken, Betty van, Harvala, Heli, Marfil, Silvia, Troxel, Andrea, Mooijaart, Simon, Trinité, Benjamin, Piccolo Ferreira, Francini, Bonet, Mireia, Cantoni, Jordi, Russcher, Henk, Marks, Michael, Zwaginga, Jaap Jan, Torrano Soler, Pamela, Mitjà, Oriol, Rijnders, Bart J. A., Droog, José de, Corbacho Monné, Marc, Scherpenisse, Cees, Hollander, Jan den, Gharbharan, Arvind, Jordans, Carlijn, Geurtsvankessel, Corine, Albersen, Arjan, Papageourgiou, Grigorios, Katsikis, Peter, Vall Mayans, Martí, Müller, Yvonne, Reusken, Chantal, San José, Alba, Ferrer, Susana, Engen, Rene van, Karisli, Ayten, Götz, Hannelore, Struik, Jelle, París, Alexa, Suñer Navarro, Clara, Clotet, Bonaventura, 1953, Reimerink, Johan, Rokx-Niemantsverdriet, Lotte, Rodriguez Arias, Miquel Angel, Jiménez, Zahida, Verstijnen, Jose, Geloven, Nan van, Groeneveld, Geert, Zwaginga, Lisa, Oud, Josine, Meier, Romy, González Beiras, Camila, Swaneveld, Francis, Ramírez Viaplana, Ferran, Schoot, Ellen van der, Vrielink, Hans, Flores Aguilera, Begoña, Vivero Larraza, Ainhoa, Watering, Leo van de, Hogema, Boris, González García, David, Wijngaarden, Peter van, Vidal Alaball, Josep, Etten, Ronald van, Gammeren, Adriaan van, Alemany, Andrea, Puig, Jordi, Maas, Nanda, Berg – Rahman, Juliette van der, Karim, Faiz, Hiddema, Siepke, Elst, Kim van, García García, Vanesa, Casañ Lopez, Cristina, Leeuwen-Segarceanu, Elena van, Nieto, Aroa, Rodríguez Sevilla, Graciela, Reitsma, Annette, Molenkamp, Karin, Soetekouw, Robert, Band, Caterina, Carceles Peiró, Victor, Gallardo, Mireia, Galvan Femenia, Ivan, Comas Leon, Xavier, Millat Martínez, Pere, Bassat Orellana, Quique, González, María Isabel, Verdaguer, Joaquim, Roquer López, Clàudia, Contreras, Enric, Giménez, Montserrat, Ouchi, Dan, Blanco Guillermo, Ignacio, Bonet Papell, Glòria, Dastis Arias, Macarena, Delgado Capel, Maria, Faculteit Medische Wetenschappen/UMCG, Internal Medicine, Medical Microbiology & Infectious Diseases, Virology, and Epidemiology

Subjects
Immunoregulació, Multidisciplinary, SARS-CoV-2, Immunization, Passive, Immunoregulation, COVID-19, General Physics and Astronomy, Bayes Theorem, General Chemistry, Middle Aged, General Biochemistry, Genetics and Molecular Biology, Treatment Outcome, Outpatients, Humans, Multicenter Studies as Topic, COVID-19 Serotherapy, Randomized Controlled Trials as Topic
Abstract

Data on convalescent plasma (CP) treatment in COVID-19 outpatients are scarce. We aimed to assess whether CP administered during the first week of symptoms reduced the disease progression or risk of hospitalization of outpatients. Two multicenter, double-blind randomized trials (NCT04621123, NCT04589949) were merged with data pooling starting when Trial registration: Clinicaltrials.gov NCT04621123 and NCT04589949. Registration: NCT04621123 and NCT04589949 on https://www.clinicaltrials.gov

Published
2022

22. People With Human Immunodeficiency Virus Receiving Suppressive Antiretroviral Therapy Show Typical Antibody Durability After Dual Coronavirus Disease 2019 Vaccination and Strong Third Dose Responses

Author

Lapointe, Hope R, primary, Mwimanzi, Francis, additional, Cheung, Peter K, additional, Sang, Yurou, additional, Yaseen, Fatima, additional, Umviligihozo, Gisele, additional, Kalikawe, Rebecca, additional, Speckmaier, Sarah, additional, Moran-Garcia, Nadia, additional, Datwani, Sneha, additional, Duncan, Maggie C, additional, Agafitei, Olga, additional, Ennis, Siobhan, additional, Young, Landon, additional, Ali, Hesham, additional, Ganase, Bruce, additional, Omondi, F Harrison, additional, Dong, Winnie, additional, Toy, Junine, additional, Sereda, Paul, additional, Burns, Laura, additional, Costiniuk, Cecilia T, additional, Cooper, Curtis, additional, Anis, Aslam H, additional, Leung, Victor, additional, Holmes, Daniel T, additional, DeMarco, Mari L, additional, Simons, Janet, additional, Hedgcock, Malcolm, additional, Prystajecky, Natalie, additional, Lowe, Christopher F, additional, Pantophlet, Ralph, additional, Romney, Marc G, additional, Barrios, Rolando, additional, Guillemi, Silvia, additional, Brumme, Chanson J, additional, Montaner, Julio S G, additional, Hull, Mark, additional, Harris, Marianne, additional, Niikura, Masahiro, additional, Brockman, Mark A, additional, and Brumme, Zabrina L, additional

Published
2022
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23. A Novel Adult Murine Model of Typical Enteroaggregative Escherichia coli Infection Reveals Microbiota Dysbiosis, Mucus Secretion, and AAF/II-Mediated Expression and Localization of β-Catenin and Expression of MUC1 in Ileum

Author

Moran-Garcia, Nadia, primary, Lopez-Saucedo, Catalina, additional, Becerra, Adriana, additional, Meza-Segura, Mario, additional, Hernandez-Cazares, Felipe, additional, Guerrero-Baez, Jair, additional, Galindo-Gómez, Silvia, additional, Tsutsumi, Víctor, additional, Schnoor, Michael, additional, Méndez-Tenorio, Alfonso, additional, Nataro, James P., additional, and Estrada-Garcia, Teresa, additional

Published
2022
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24. SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8+ T-cells

Author

Jones, R. Brad, primary, Stevenson, Eva, additional, Terry, Sandra, additional, Copertino, Dennis, additional, Leyre, Louise, additional, Ward, Adam, additional, Khadka, Pragya, additional, Ellsworth, Grant, additional, Johnston, Carrie, additional, Papa, Michelle Premazzi, additional, Nicholes, Samuel, additional, Caskey, Marina, additional, Gaebler, Christian, additional, Wilkin, Timothy, additional, Lynch, Rebecca, additional, Lee, Guinevere, additional, Weiler, Jared, additional, Zumbo, Paul, additional, Betel, Doron, additional, Dündar, Friederike, additional, Duncan, Maggie, additional, Lapointe, Hope, additional, Speckmaier, Sarah, additional, Moran-Garcia, Nadia, additional, Chun, Tae-Wook, additional, Brumme, Zabrina, additional, Danesh, Ali, additional, Bernard, Kevin, additional, Stover, Carissa, additional, and McNeil, Evan, additional

Published
2022
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25. People with HIV receiving suppressive antiretroviral therapy show typical antibody durability after dual COVID-19 vaccination, and strong third dose responses

Author

Lapointe, Hope R., primary, Mwimanzi, Francis, additional, Cheung, Peter K., additional, Sang, Yurou, additional, Yaseen, Fatima, additional, Umviligihozo, Gisele, additional, Kalikawe, Rebecca, additional, Speckmaier, Sarah, additional, Moran-Garcia, Nadia, additional, Datwani, Sneha, additional, Duncan, Maggie C., additional, Agafitei, Olga, additional, Ennis, Siobhan, additional, Young, Landon, additional, Ali, Hesham, additional, Ganase, Bruce, additional, Omondi, F. Harrison, additional, Dong, Winnie, additional, Toy, Junine, additional, Sereda, Paul, additional, Burns, Laura, additional, Costiniuk, Cecilia T., additional, Cooper, Curtis, additional, Anis, Aslam H., additional, Leung, Victor, additional, Holmes, Daniel, additional, DeMarco, Mari L., additional, Simons, Janet, additional, Hedgcock, Malcolm, additional, Prystajecky, Natalie, additional, Lowe, Christopher F., additional, Pantophlet, Ralph, additional, Romney, Marc G., additional, Barrios, Rolando, additional, Guillemi, Silvia, additional, Brumme, Chanson J., additional, Montaner, Julio S.G., additional, Hull, Mark, additional, Harris, Marianne, additional, Niikura, Masahiro, additional, Brockman, Mark A., additional, and Brumme, Zabrina L., additional

Published
2022
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26. MROS: runtime adaptation for robot control architectures

Author

Bozhinoski, Darko, primary, Garzon Oviedo, Mario, additional, Hammoudeh Garcia, Nadia, additional, Deshpande, Harshavardhan, additional, van der Hoorn, Gijs, additional, Tjerngren, Jon, additional, Wąsowski, Andrzej, additional, and Hernandez Corbato, Carlos, additional

Published
2022
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27. High-titre methylene blue-treated convalescent plasma as an early treatment for outpatients with COVID-19: a randomised, placebo-controlled trial

Author

Alemany, Andrea, primary, Millat-Martinez, Pere, additional, Corbacho-Monné, Marc, additional, Malchair, Pierre, additional, Ouchi, Dan, additional, Ruiz-Comellas, Anna, additional, Ramírez-Morros, Anna, additional, Rodríguez Codina, Joana, additional, Amado Simon, Rosa, additional, Videla, Sebastian, additional, Costes, Gèlia, additional, Capdevila-Jáuregui, Mar, additional, Torrano-Soler, Pamela, additional, San José, Alba, additional, Bonet Papell, Glòria, additional, Puig, Jordi, additional, Otero, Aurema, additional, Ruibal Suarez, Jose Carlos, additional, Zarauza Pellejero, Alvaro, additional, Llopis Roca, Ferran, additional, Rodriguez Cortez, Orlando, additional, Garcia Garcia, Vanesa, additional, Vidal-Alaball, Josep, additional, Millan, Anna, additional, Contreras, Enric, additional, Grifols, Joan-Ramon, additional, Ancochea, Àgueda, additional, Galvan-Femenia, Ivan, additional, Piccolo Ferreira, Francini, additional, Bonet, Mireia, additional, Cantoni, Jordi, additional, Prat, Núria, additional, Ara, Jordi, additional, Forcada Arcarons, Anna, additional, Farré, Magí, additional, Pradenas, Edwards, additional, Blanco, Julià, additional, Àngel Rodriguez-Arias, Miquel, additional, Fernández Rivas, Gema, additional, Marks, Michael, additional, Bassat, Quique, additional, Blanco, Ignacio, additional, Baro, Bàrbara, additional, Clotet, Bonaventura, additional, Mitjà, Oriol, additional, Ferrer, Susana, additional, Gallardo, Mireia, additional, Ubals, Maria, additional, González-Beiras, Camila, additional, Vall-Mayans, Martí, additional, Suñer, Clara, additional, Laporte-Villar, Clàudia, additional, Nieto, Aroa, additional, Comas-Leon, Xavier, additional, Jiménez, Zahida, additional, Ramírez-Viaplana, Ferran, additional, Delgado-Capel, Maria, additional, Díez Sánchez, Beatriz, additional, Pons Barber, Maria, additional, Gonzalez Ruiz, Cristian, additional, Navarrete Gonzalez, Laura, additional, González García, David, additional, Vivero Larraza, Ainhoa, additional, Carceles Peiró, Victor, additional, Roquer López, Clàudia, additional, Robert, Neus, additional, Palet, Carles, additional, Gudiol, Carlota, additional, Casares Gonzalez, Pablo, additional, Arcos Vila, Gemma, additional, Flores Aguilera, Begoña, additional, Rodríguez-Sevilla, Graciela, additional, Dastis Arias, Macarena, additional, Roca Font, Judit, additional, Carrasco Matos, Katherine M., additional, Saüch Valmaña, Glòria, additional, Vidal Obradors, Carla, additional, Tarres García, Silvia, additional, Curriu Sabatès, Margarida, additional, Nieto Rodríguez, Raquel, additional, Línio, Rosa, additional, Fornos, Míriam, additional, Casamitjana, Natàlia, additional, Alonso, Eva, additional, Martínez, Núria, additional, Maglio, Laura Analía, additional, Comellas Fernandez, Laura, additional, Garcia, Nadia, additional, Hernández, Luis, additional, González, Maria Isabel, additional, Bravo, Anna, additional, García, Yolanda, additional, Sauleda Oliveras, Silvia, additional, Vertiz, Tatiana, additional, Benavent, Sergio, additional, Bianco, Andrea Sofia, additional, Verdaguer, Joaquim, additional, Briones Zambrano, Ney Nicanor, additional, Viozquez Meya, Maria, additional, Hernández, Águeda, additional, Casaña Lopez, Cristina, additional, Bordoy, Antoni E., additional, González Soler, Victoria, additional, Giménez, Montserrat, additional, París, Alexa, additional, Marfil, Silvia, additional, Trinité, Benjamin, additional, and Grau, Eulàlia, additional

Published
2022
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28. Characteristics and outcomes of cases of children and adolescents with pediatric inflammatory multisystem syndrome in a tertiary care centre in Mexico City.

Author

Gil Guevara, Ricardo, primary, Marroquin Yanez, Maria de Lourdes, additional, Jimenez-Juarez, Rodolfo Norberto, additional, Olivar Lopez, Victor, additional, Lopez, Adrian Chavez, additional, Sienra Monge, Juan Jose Luis, additional, Erdmenger Orellana, Julio, additional, Jamaica Balderas, Lourdes Maria del Carmen, additional, Martinez Herrera, Silvia Alexandra, additional, Dominguez-Barrera, Clemen, additional, Marquez Gonzalez, Horacio, additional, Klunder-Klunder, Miguel, additional, Nieto-Zermeno, Jaime, additional, Villa Guillen, Monica, additional, Garcia, Nadia Gonzalez, additional, and Castilla Peon, Maria Fernanda, additional

Published
2021
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29. Humoral immune responses to COVID-19 vaccination in people living with HIV receiving suppressive antiretroviral therapy

Author

Brumme, Zabrina L., primary, Mwimanzi, Francis, additional, Lapointe, Hope R., additional, Cheung, Peter, additional, Sang, Yurou, additional, Duncan, Maggie C., additional, Yaseen, Fatima, additional, Agafitei, Olga, additional, Ennis, Siobhan, additional, Ng, Kurtis, additional, Basra, Simran, additional, Lim, Li Yi, additional, Kalikawe, Rebecca, additional, Speckmaier, Sarah, additional, Moran-Garcia, Nadia, additional, Young, Landon, additional, Ali, Hesham, additional, Ganase, Bruce, additional, Umviligihozo, Gisele, additional, Omondi, F. Harrison, additional, Atkinson, Kieran, additional, Sudderuddin, Hanwei, additional, Toy, Junine, additional, Sereda, Paul, additional, Burns, Laura, additional, Costiniuk, Cecilia T., additional, Cooper, Curtis, additional, Anis, Aslam H., additional, Leung, Victor, additional, Holmes, Daniel, additional, DeMarco, Mari L., additional, Simons, Janet, additional, Hedgcock, Malcolm, additional, Romney, Marc G., additional, Barrios, Rolando, additional, Guillemi, Silvia, additional, Brumme, Chanson J., additional, Pantophlet, Ralph, additional, Montaner, Julio S.G., additional, Niikura, Masahiro, additional, Harris, Marianne, additional, Hull, Mark, additional, and Brockman, Mark A., additional

Published
2021
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31. Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis

Author

Universitat Rovira i Virgili, Herranz, Carmen; Mateo, Francesca; Baiges, Alexandra; de Garibay, Gorka Ruiz; Junza, Alexandra; Johnson, Simon R.; Miller, Suzanne; Garcia, Nadia; Capellades, Jordi; Gomez, Antonio; Vidal, August; Palomero, Luis; Espin, Roderic; Extremera, Ana, I; Blommaert, Eline; Revilla-Lopez, Eva; Saez, Berta; Gomez-Olles, Susana; Ancochea, Julio; Valenzuela, Claudia; Alonso, Tamara; Ussetti, Piedad; Laporta, Rosalia; Xaubet, Antoni; Rodriguez-Portal, Jose A.; Montes-Worboys, Ana; Machahua, Carlos; Bordas, Jaume; Menendez, Javier A.; Cruzado, Josep M.; Guiteras, Roser; Bontoux, Christophe; La Motta, Concettina; Noguera-Castells, Aleix; Mancino, Mario; Lastra, Enrique; Rigo-Bonnin, Raul; Perales, Jose C.; Vinals, Francesc; Lahiguera, Alvaro; Zhang, Xiaohu; Cuadras, Daniel; van Moorsel, Coline H. M.; van der Vis, Joanne J.; Quanjel, Marian J. R.; Filippakis, Harilaos; Hakem, Razq; Gorrini, Chiara; Ferrer, Marc; Ugun-Klusek, Aslihan; Billett, Ellen; Radzikowska, Elzbieta; Casanova, Alvaro; Molina-Molina, Maria; Roman, Antonio; Yanes, Oscar; Pujana, Miquel A., Universitat Rovira i Virgili, and Herranz, Carmen; Mateo, Francesca; Baiges, Alexandra; de Garibay, Gorka Ruiz; Junza, Alexandra; Johnson, Simon R.; Miller, Suzanne; Garcia, Nadia; Capellades, Jordi; Gomez, Antonio; Vidal, August; Palomero, Luis; Espin, Roderic; Extremera, Ana, I; Blommaert, Eline; Revilla-Lopez, Eva; Saez, Berta; Gomez-Olles, Susana; Ancochea, Julio; Valenzuela, Claudia; Alonso, Tamara; Ussetti, Piedad; Laporta, Rosalia; Xaubet, Antoni; Rodriguez-Portal, Jose A.; Montes-Worboys, Ana; Machahua, Carlos; Bordas, Jaume; Menendez, Javier A.; Cruzado, Josep M.; Guiteras, Roser; Bontoux, Christophe; La Motta, Concettina; Noguera-Castells, Aleix; Mancino, Mario; Lastra, Enrique; Rigo-Bonnin, Raul; Perales, Jose C.; Vinals, Francesc; Lahiguera, Alvaro; Zhang, Xiaohu; Cuadras, Daniel; van Moorsel, Coline H. M.; van der Vis, Joanne J.; Quanjel, Marian J. R.; Filippakis, Harilaos; Hakem, Razq; Gorrini, Chiara; Ferrer, Marc; Ugun-Klusek, Aslihan; Billett, Ellen; Radzikowska, Elzbieta; Casanova, Alvaro; Molina-Molina, Maria; Roman, Antonio; Yanes, Oscar; Pujana, Miquel A.

Abstract

Inhibition of mTOR is the standard of care for lymphangioleiomyomatosis (LAM). However, this therapy has variable tolerability and some patients show progressive decline of lung function despite treatment. LAM diagnosis and monitoring can also be challenging due to the heterogeneity of symptoms and insufficiency of non-invasive tests. Here, we propose monoamine-derived biomarkers that provide preclinical evidence for novel therapeutic approaches. The major histamine-derived metabolite methylimidazoleacetic acid (MIAA) is relatively more abundant in LAM plasma, and MIAA values are independent of VEGF-D. Higher levels of histamine are associated with poorer lung function and greater disease burden. Molecular and cellular analyses, and metabolic profiling confirmed active histamine signaling and metabolism. LAM tumorigenesis is reduced using approved drugs targeting monoamine oxidases A/B (clorgyline and rasagiline) or histamine H1 receptor (loratadine), and loratadine synergizes with rapamycin. Depletion of Maoa or Hrh1 expression, and administration of an L-histidine analog, or a low L-histidine diet, also reduce LAM tumorigenesis. These findings extend our knowledge of LAM biology and suggest possible ways of improving disease management.

Published
2021

32. Bootstrapping MDE development from ROS manual code. Part 2 - Model generation and leveraging models at runtime

Author

Hammoudeh Garcia, Nadia, Deshpande, Harshavardhan, Santos, Andre, Kahl, Björn, Bordignon, Mirko, and Publica

Subjects
Robot Operating System (ROS), Robotik, Model Driven Engineering (MDE)
Abstract

Model-driven engineering (MDE) addresses central aspects of robotics software development. MDE could enable domain experts to leverage the expressiveness of models, while implementation details on different hardware platforms would be handled by automatic code generation. Today, despite strong MDE efforts in the robotics research community, most evidence points to manual code development being the norm. A possible reason for MDE not being accepted by robot software developers could be the wide range of applications and target platforms, which make all-encompassing MDE IDEs hard to develop and maintain. Therefore, we chose to leverage a large corpus of open-source software widely adopted by the robotics community to extract common structures and gain insight on how and where MDE can support the developers to work more efficiently. We pursue modeling as a complement, rather than imposing MDE as separate solution. Our previous work introduced metamodels to describe components, their interactions, and their resulting composition. In this paper, we present two methods based on metamodels for automated generation of models from manually written artifacts: through static code analysis and by monitoring the execution of a running system. For both methods, we present tools that leverage the potentials of our contributions, with a special focus on their application at runtime to observe and diagnose a real system during its execution. A comprehensive example is provided as a walk-through for robotics software practitioners.

Published
2021

33. Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: Results from the EPIC-EURGAST study

Author

Espinosa-Parrilla, Yolanda, Muñoz, Xavier, Bonet, Catalina, Garcia, Nadia, Venceslá, Adoración, Yiannakouris, Nikos, Naccarati, Alessio, Sieri, Sabina, Panico, Salvatore, Huerta, José M., Barricarte, Aurelio, Menéndez, Virginia, Sánchez-Cantalejo, Emilio, Dorronsoro, Miren, Brennan, Paul, Duarte-Salles, Talita, Bueno-de-Mesquita, B(as) H., Weiderpass, Elisabete, Lund, Eiliv, Clavel-Chapelon, Françoise, Boutron-Ruault, Marie-Christine, Racine, Antoine, Numans, Mattijs E., Tumino, Rosario, Canzian, Federico, Campa, Daniele, Sund, Malin, Johansson, Mattias, Ohlsson, Bodil, Lindkvist, Björn, Overvad, Kim, Tjnneland, Anne, Palli, Domenico, Travis, Ruth C., Khaw, Kay-Tee, Wareham, Nick, Boeing, Heiner, Nesi, Gabriella, Riboli, Elio, Gonzalez, Carlos A., and Sala, Núria

Published
2014
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34. La Omisión en la Regulación Normativa Fiscal Mexicana y la del Obligado Solidario ante la Retención y Entero de los Impuestos en las Cesiones de Derechos Adjudicatarios.

Author

Cruz Garcia, Nadia Maleny and Navejas Juárez, Gloria Araceli

Abstract

Copyright of Congreso Internacional de Investigacion Academia Journals is the property of PDHTech, LLC and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022

36. Validation of the adjusted global antiphospholipid syndrome score in systemic lupus erythematosus patients in Argentina

Author

Garcia, Lucila, primary, Velloso, Maria S, additional, Martire, Maria V, additional, Savy, Florencia, additional, Arizpe, Fernando, additional, Garcia, Nadia, additional, Testi, Adriana, additional, Pena, Claudia, additional, Costi, Ana C, additional, Isnardi, Carolina, additional, Capelusnik, Dafne, additional, Mazza, Susana, additional, Curi, Yessika Soria, additional, Collado, Victoria, additional, Rodriguez, Maria F, additional, Scarafia, Santiago, additional, Pisoni, Cecilia, additional, de la Torre, Maria, additional, Seewald, Adriana, additional, Riva, Maria E, additional, and Garcia, Mercedes, additional

Published
2020
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38. Through the looking-glass: the interartistic practice of Remedios Varo

Author

Albaladejo Garcia, Nadia, Finnegan, Nuala, and Buffery, Helena

Subjects
Exile, Interdisciplinarity, Mexican art, Women's studies, Spanish art, Art history, Surrealism
Abstract

This thesis sets out to map and explore the interartistic practice and relations developed in the creative production of twentieth-century woman artist and writer, Remedios Varo i Uranga (Anglès, Girona 1908 - Mexico City, 1963), who achieved significant international recognition for one aspect of her work: her paintings. I explore and analyse key examples of her interartistic practice throughout her career. These include: Varo’s literary experiments, co-creating the surrealist play El santo cuerpo grasoso with Leonora Carrington; the commercial commissions she carried out for Bayer which is here read in relation to their context of publication; her best-known sculptural work, Homo rodans, examined in relation to the hybrid text which accompanied it and the various traces of its performative composition; and her most famous ‘treatise’ on interartistic practice, the painting La creación de las aves, which is read alongside a selection of her dream narratives. These works are primarily analysed using an interdisciplinary framework that includes cultural and literary studies, theatre and performance studies as well as anthropology and philosophy. Overall, the analysis demonstrates that the extant critical insistence on translating her into a single dominant frame or worldview, even while recognising the importance of her diasporic mobility, ultimately reduces the liminal, performative and often playful nature of her work and downplays her capacity to negotiate and move between different languages, cultures, media and disciplines.

Published
2019

39. Adaptation of a web-based, open source electronic medical record system platform to support a large study of tuberculosis epidemiology

Author

Fraser Hamish SF, Thomas David, Tomaylla Juan, Garcia Nadia, Lecca Leonid, Murray Megan, and Becerra Mercedes C

Subjects
Electronic medical record, Developing country, Multidrug-resistant tuberculosis, MDR-TB, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

Abstract Background In 2006, we were funded by the US National Institutes of Health to implement a study of tuberculosis epidemiology in Peru. The study required a secure information system to manage data from a target goal of 16,000 subjects who needed to be followed for at least one year. With previous experience in the development and deployment of web-based medical record systems for TB treatment in Peru, we chose to use the OpenMRS open source electronic medical record system platform to develop the study information system. Supported by a core technical and management team and a large and growing worldwide community, OpenMRS is now being used in more than 40 developing countries. We adapted the OpenMRS platform to better support foreign languages. We added a new module to support double data entry, linkage to an existing laboratory information system, automatic upload of GPS data from handheld devices, and better security and auditing of data changes. We added new reports for study managers, and developed data extraction tools for research staff and statisticians. Further adaptation to handle direct entry of laboratory data occurred after the study was launched. Results Data collection in the OpenMRS system began in September 2009. By August 2011 a total of 9,256 participants had been enrolled, 102,274 forms and 13,829 laboratory results had been entered, and there were 208 users. The system is now entirely supported by the Peruvian study staff and programmers. Conclusions The information system served the study objectives well despite requiring some significant adaptations mid-stream. OpenMRS has more tools and capabilities than it did in 2008, and requires less adaptations for future projects. OpenMRS can be an effective research data system in resource poor environments, especially for organizations using or considering it for clinical care as well as research.

Published
2012
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41. 248 Validation of the adjusted global anti-phospholipid syndrome score in the argentine population

Author

Garcia, Lucila, primary, Velloso, Sofia, additional, Martire, Victoria, additional, Savy, Florencia, additional, Arizpe, Fernando, additional, Garcia, Nadia, additional, Testi, Adriana, additional, Pena, Claudia, additional, Isnardi, Carolina, additional, Capelusnik, Dafne, additional, Collado, Victoria, additional, Rodriguez, Florencia, additional, Mazza, Susana, additional, Curi, Yessika Soria, additional, and Garcia, Mercedes, additional

Published
2019
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43. High-titre methylene blue-treated convalescent plasma as an early treatment for outpatients with COVID-19: a randomised, placebo-controlled trial

Author

Alemany, Andrea, Millat-Martinez, Pere, Corbacho-Monné, Marc, Malchair, Pierre, Ouchi, Dan, Ruiz-Comellas, Anna, Ramírez-Morros, Anna, Rodríguez Codina, Joana, Amado Simon, Rosa, Videla, Sebastian, Costes, Gèlia, Capdevila-Jáuregui, Mar, Torrano-Soler, Pamela, San José, Alba, Bonet Papell, Glòria, Puig, Jordi, Otero, Aurema, Ruibal Suarez, Jose Carlos, Zarauza Pellejero, Alvaro, Llopis Roca, Ferran, Rodriguez Cortez, Orlando, Garcia Garcia, Vanesa, Vidal-Alaball, Josep, Millan, Anna, Contreras, Enric, Grifols, Joan-Ramon, Ancochea, Àgueda, Galvan-Femenia, Ivan, Piccolo Ferreira, Francini, Bonet, Mireia, Cantoni, Jordi, Prat, Núria, Ara, Jordi, Forcada Arcarons, Anna, Farré, Magí, Pradenas, Edwards, Blanco, Julià, Àngel Rodriguez-Arias, Miquel, Fernández Rivas, Gema, Marks, Michael, Bassat, Quique, Blanco, Ignacio, Baro, Bàrbara, Clotet, Bonaventura, Mitjà, Oriol, Ferrer, Susana, Gallardo, Mireia, Ubals, Maria, González-Beiras, Camila, Vall-Mayans, Martí, Suñer, Clara, Laporte-Villar, Clàudia, Nieto, Aroa, Comas-Leon, Xavier, Jiménez, Zahida, Ramírez-Viaplana, Ferran, Delgado-Capel, Maria, Díez Sánchez, Beatriz, Pons Barber, Maria, Gonzalez Ruiz, Cristian, Navarrete Gonzalez, Laura, González García, David, Vivero Larraza, Ainhoa, Carceles Peiró, Victor, Roquer López, Clàudia, Robert, Neus, Palet, Carles, Gudiol, Carlota, Casares Gonzalez, Pablo, Arcos Vila, Gemma, Flores Aguilera, Begoña, Rodríguez-Sevilla, Graciela, Dastis Arias, Macarena, Roca Font, Judit, Carrasco Matos, Katherine M., Saüch Valmaña, Glòria, Vidal Obradors, Carla, Tarres García, Silvia, Curriu Sabatès, Margarida, Nieto Rodríguez, Raquel, Línio, Rosa, Fornos, Míriam, Casamitjana, Natàlia, Alonso, Eva, Martínez, Núria, Maglio, Laura Analía, Comellas Fernandez, Laura, Garcia, Nadia, Hernández, Luis, González, Maria Isabel, Bravo, Anna, García, Yolanda, Sauleda Oliveras, Silvia, Vertiz, Tatiana, Benavent, Sergio, Bianco, Andrea Sofia, Verdaguer, Joaquim, Briones Zambrano, Ney Nicanor, Viozquez Meya, Maria, Hernández, Águeda, Casaña Lopez, Cristina, Bordoy, Antoni E., González Soler, Victoria, Giménez, Montserrat, París, Alexa, Marfil, Silvia, Trinité, Benjamin, and Grau, Eulàlia

Abstract

Convalescent plasma has been proposed as an early treatment to interrupt the progression of early COVID-19 to severe disease, but there is little definitive evidence. We aimed to assess whether early treatment with convalescent plasma reduces the risk of hospitalisation and reduces SARS-CoV-2 viral load among outpatients with COVID-19.

Published
2024
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46. CD30 Expression in Diffuse Large B-Cell Lymphoma (DLBCL) Correlates with Non-GCB Subtype but Does Not Have Prognostic Impact in Patients Treated with First Line R-CHOP/R-CHOP-like

Author

Salas, Maria Queralt, primary, Climent, Fina, additional, Domingo Domenech, Eva, additional, Mercadal, Santiago, additional, Paredes, Viviana, additional, Oliveira, Ana Carla, additional, Aguilera, Carmen, additional, de la Banda, Esmeralda, additional, Lucas, Anna, additional, Garcia, Nadia, additional, Baca, Cristina, additional, Fernandez de Sevilla, Alberto, additional, Sureda, Anna, additional, Gonzalez Barca, Eva, additional, and Riasol, Maria Lutgarda, additional

Published
2016
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47. Genetic variants in the IL1A gene region contribute to intestinal-type gastric carcinoma susceptibility in European populations

Author

Duraes, Cecilia Munoz, Xavier Bonet, Catalina Garcia, Nadia and Vencesla, Adoracion Carneiro, Fatima Peleteiro, Barbara and Lunet, Nuno Barros, Henrique Lindkvist, Bjorn and Boutron-Ruault, Marie-Christine Bueno-de-Mesquita, H. B(as) and Rizzato, Cosmeri Trichopoulou, Antonia Weiderpass, Elisabete and Naccarati, Allessio Travis, Ruth C. Tjonneland, Anne and Barricarte Gurrea, Aurelio Johansson, Mattias Riboli, Elio and Figueiredo, Ceu Gonzalez, Carlos Alberto Capella, Gabriel and Machado, Jose Carlos Sala, Nuria

Abstract

The most studied genetic susceptibility factors involved in gastric carcinoma (GC) risk are polymorphisms in the inflammation-linked genes interleukin 1 (IL1) B and IL1RN. Despite the evidence pointing to the IL1 region, definite functional variants reproducible across populations of different genetic background have not been discovered so far. A high density linkage disequilibrium (LD) map of the IL1 gene cluster was established using HapMap to identify haplotype tagSNPs. Eighty-seven SNPs were genotyped in a Portuguese case-control study (358 cases, 1,485 controls) for the discovery analysis. A replication study, including a subset of those tagSNPs (43), was performed in an independent analysis (EPIC-EurGast) containing individuals from 10 European countries (365 cases, 1284 controls). Single SNP and haplotype block associations were determined for GC overall and anatomopathological subtypes. The most robust association was observed for SNP rs17042407, 16Kb upstream of the IL1A gene. Although several other SNP associations were observed, only the inverse association of rs17042407 allele C with GC of the intestinal type was observed in both studies, retaining significance after multiple testing correction (p = 0.0042) in the combined analysis. The haplotype analysis of the IL1A LD block in the combined dataset revealed the association between a common haplotype carrying the rs17042407 variant and GC, particularly of the intestinal type (p = 3.1 x 10(-5)) and non cardia localisation (p = 4.6 x 10(-3)). These results confirm the association of IL1 gene variants with GC and reveal a novel SNP and haplotypes in the IL1A region associated with intestinal type GC in European populations.

Published
2014

48. Sa1927 Significant Genetic Variability Associated With the Evolution of Gastric Cancer Precursor Lesions in a Spanish Population

Author

Companioni, Osmel, primary, Bonet, Catalina, additional, Garcia, Nadia, additional, Sanz-Anquela, José Miguel, additional, Berdasco, María, additional, Adrados, Magdalena, additional, Mendoza, Jorge, additional, Collantes, Elena, additional, Ruiz, G., additional, Rey, Enrique, additional, Sánchez-Ceballos, Francisco, additional, Poves, Elvira, additional, Espinosa, Laura, additional, Madrigal, Beatriz, additional, Barrio, Jesus, additional, Cuatrecasas, Miriam, additional, Elizalde, Josep Ignasi, additional, Bujanda, Luis, additional, Cosme, Angel, additional, Ferrandez, Angel, additional, Muñoz, Guillermo, additional, Andreu, Victoria, additional, Paules, María José, additional, Lario, Sergio, additional, Lázaro, María José Ramírez, additional, Gisbert, Javier P., additional, Gonzalez, Carlos A., additional, and Sala, Núria, additional

Published
2015
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49. Polymorphisms in metabolic genes related to tobacco smoke and the risk of gastric cancer in the European prospective investigation into cancer and nutrition

Author

Agudo, Antonio Sala, Nuria Pera, Guillem Capella, Gabriel and Berenguer, Antonio Garcia, Nadia Palli, Domenico Boeing, Heiner Del Giudice, Giuseppe Saieva, Calogero Carneiro, Fatima Berrino, Franco Sacerdote, Carlotta Tumino, Rosario and Panico, Salvatore Berglund, Goran Siman, Henrik and Stenling, Roger Hallmans, Goran Martinez, Carmen Bilbao, Roberto Barricarte, Aurelio Navarro, Carmen Quiros, Jose R. and Allen, Naomi Key, Tim Bingham, Sheila Khaw, Kay-Tee and Linseisen, Jakob Nagel, Gabriele Overvad, Kim Tjonneland, Anne Olsen, Anja Bueno-de-Mesquita, H. Bas Boshuizen, Hendriek C. Peeters, Petra H. Numans, Mattijs E. and Clavel-Chapelon, Francoise Boutron-Ruault, Marie-Christine and Trichopoulou, Antonia Lund, Eiliv Offerhaus, Johan Jenab, Mazda Ferrari, Pietro Norat, Teresa Riboli, Elio and Gonzalez, Carlos A.

Abstract

Metabolizing enzymes, which often display genetic polymorphisms, are involved in the activation of compounds present in tobacco smoke that may be relevant to gastric carcinogenesis. We report the results of a study looking at the association between risk of gastric adenocarcinoma and polymorphisms in genes CYP1A1, CYP1A2, EPHX1, and GSTT1. A nested case-control study was carried out within the European Prospective Investigation into Cancer and Nutrition, developed in 10 European countries. The study includes 243 newly diagnosed cases of histologically confirmed gastric adenocarcinoma and 946 controls matched by center, age, sex, and date of blood collection. Genotypes were determined in nuclear DNA from WBCs. We found an increased risk of gastric cancer for homozygotes for C (histidine) variant in Y113H of EPHX1 (odds ratio, 1.91; 95% confidence interval, 1.19-3.07) compared with subjects with TC/TT. There was also a significant increased risk for smokers carrying at least one variant allele A in Ex7+129C > A (m4) of CYP1A1 and never smokers with null GSTT1 and allele A in the locus -3859G > A of CYP1A2. Most of these genes are involved in the activation and detoxification of polycyclic aromatic hydrocarbons, suggesting a potential role of these compounds in gastric carcinogenesis.

Published
2006

50. Genetic association of gastric cancer with miRNA clusters including the cancer-related genesMIR29, MIR25, MIR93andMIR106: Results from the EPIC-EURGAST study

Author

Espinosa-Parrilla, Yolanda, primary, Muñoz, Xavier, additional, Bonet, Catalina, additional, Garcia, Nadia, additional, Venceslá, Adoración, additional, Yiannakouris, Nikos, additional, Naccarati, Alessio, additional, Sieri, Sabina, additional, Panico, Salvatore, additional, Huerta, José M., additional, Barricarte, Aurelio, additional, Menéndez, Virginia, additional, Sánchez-Cantalejo, Emilio, additional, Dorronsoro, Miren, additional, Brennan, Paul, additional, Duarte-Salles, Talita, additional, Bas Bueno-de-Mesquita, H., additional, Weiderpass, Elisabete, additional, Lund, Eiliv, additional, Clavel-Chapelon, Françoise, additional, Boutron-Ruault, Marie-Christine, additional, Racine, Antoine, additional, Numans, Mattijs E., additional, Tumino, Rosario, additional, Canzian, Federico, additional, Campa, Daniele, additional, Sund, Malin, additional, Johansson, Mattias, additional, Ohlsson, Bodil, additional, Lindkvist, Björn, additional, Overvad, Kim, additional, Tjønneland, Anne, additional, Palli, Domenico, additional, Travis, Ruth C., additional, Khaw, Kay-Tee, additional, Wareham, Nick, additional, Boeing, Heiner, additional, Nesi, Gabriella, additional, Riboli, Elio, additional, Gonzalez, Carlos A., additional, and Sala, Núria, additional

Published
2014
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