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Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients
- Source :
- Nature Communications, 13(1):2583. Nature Publishing Group, Nature Communications, 13(1). NATURE PORTFOLIO, Dipòsit Digital de la UB, Universidad de Barcelona, Nature Communications, r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol, instname
- Publication Year :
- 2022
-
Abstract
- Data on convalescent plasma (CP) treatment in COVID-19 outpatients are scarce. We aimed to assess whether CP administered during the first week of symptoms reduced the disease progression or risk of hospitalization of outpatients. Two multicenter, double-blind randomized trials (NCT04621123, NCT04589949) were merged with data pooling starting when Trial registration: Clinicaltrials.gov NCT04621123 and NCT04589949. Registration: NCT04621123 and NCT04589949 on https://www.clinicaltrials.gov
- Subjects :
- Immunoregulació
Multidisciplinary
SARS-CoV-2
Immunization, Passive
Immunoregulation
COVID-19
General Physics and Astronomy
Bayes Theorem
General Chemistry
Middle Aged
General Biochemistry, Genetics and Molecular Biology
Treatment Outcome
Outpatients
Humans
Multicenter Studies as Topic
COVID-19 Serotherapy
Randomized Controlled Trials as Topic
Subjects
Details
- Language :
- English
- ISSN :
- 04621123 and 20411723
- Database :
- OpenAIRE
- Journal :
- Nature Communications, 13(1):2583. Nature Publishing Group, Nature Communications, 13(1). NATURE PORTFOLIO, Dipòsit Digital de la UB, Universidad de Barcelona, Nature Communications, r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol, instname
- Accession number :
- edsair.doi.dedup.....95c77aa3e3dc12f8ba5a8cff738dae92