1. The effect of two different modes of anaesthesia maintenance on postoperative delirium in elderly patient with low preoperative mini-cog score.
- Author
-
Duran HT, Kızılkaya M, Aydinli A, Osmantevfik S, Taştan S, Kılınç OÖ, and Pirhan Y
- Subjects
- Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Anesthesia, Intravenous methods, Delirium epidemiology, Delirium prevention & control, Emergence Delirium epidemiology, Emergence Delirium prevention & control, Incidence, Postoperative Complications epidemiology, Postoperative Complications prevention & control, Prospective Studies, Anesthetics, Inhalation adverse effects, Anesthetics, Inhalation administration & dosage, Cholecystectomy, Laparoscopic methods, Sevoflurane administration & dosage
- Abstract
Background: Postoperative delirium is a common distressing symptom experienced following laparoscopic cholecystectomy. The study aimed to investigate the influence of a low preoperative Mini-Cog testing score and 2 different anesthesia methods: total intravenous anaesthesia (TIVA) versus sevoflurane, on postoperative delirium in elderly patients undergoing laparoscopic cholecystectomy., Methods: A total of 84 patients over 60 years old who underwent laparoscopic cholecystectomy between March 1and - October 1 2023 were included in the study. Patients with a Mini-Cog score of 0-2 were considered to have low and possibly impaired neurocognitive function. We invastigated the effects of preoperative Mini-Cog score and the two anesthesia methods used on the incidence of postoperative delirium., Results: The proportion of patients with low Mini-Cog score in the preoperative period was 17.9%. Sevoflurane and TIVA was used in 41 and 43 patients respectively. The incidence of postoperative delirium in patients with low preoperative Mini-Cog scores was 66.7% at postoperative 0 h and 33.3% at the 1st hours. Postoperative delirium was found to be statistically higher in patients with low Mini-cog scores than in those with negatively-screened for Mini-cog scores (p: 0.01-0.035). In patients using sevoflurane, the incidence of postoperative delirium was 26.8% and 24.4% at the 0 and 1st hours, respectively. This was found to be statistically higher than in patients receiving TIVA (p: 0.036 - 0.010)., Conclusion: Low Mini-Cog score was an indicator of a higher risk of early postoperative delirium. Sevoflurane is more likely to cause postoperative delirium than TIVA., Trial Registration: The study was registered on ClinicalTrials.gov (Identifier: NCT06597812) ., (© 2024. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF