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The effect of two different modes of anaesthesia maintenance on postoperative delirium in elderly patient with low preoperative mini-cog score.
- Source :
-
BMC anesthesiology [BMC Anesthesiol] 2024 Oct 01; Vol. 24 (1), pp. 350. Date of Electronic Publication: 2024 Oct 01. - Publication Year :
- 2024
-
Abstract
- Background: Postoperative delirium is a common distressing symptom experienced following laparoscopic cholecystectomy. The study aimed to investigate the influence of a low preoperative Mini-Cog testing score and 2 different anesthesia methods: total intravenous anaesthesia (TIVA) versus sevoflurane, on postoperative delirium in elderly patients undergoing laparoscopic cholecystectomy.<br />Methods: A total of 84 patients over 60 years old who underwent laparoscopic cholecystectomy between March 1and - October 1 2023 were included in the study. Patients with a Mini-Cog score of 0-2 were considered to have low and possibly impaired neurocognitive function. We invastigated the effects of preoperative Mini-Cog score and the two anesthesia methods used on the incidence of postoperative delirium.<br />Results: The proportion of patients with low Mini-Cog score in the preoperative period was 17.9%. Sevoflurane and TIVA was used in 41 and 43 patients respectively. The incidence of postoperative delirium in patients with low preoperative Mini-Cog scores was 66.7% at postoperative 0 h and 33.3% at the 1st hours. Postoperative delirium was found to be statistically higher in patients with low Mini-cog scores than in those with negatively-screened for Mini-cog scores (p: 0.01-0.035). In patients using sevoflurane, the incidence of postoperative delirium was 26.8% and 24.4% at the 0 and 1st hours, respectively. This was found to be statistically higher than in patients receiving TIVA (p: 0.036 - 0.010).<br />Conclusion: Low Mini-Cog score was an indicator of a higher risk of early postoperative delirium. Sevoflurane is more likely to cause postoperative delirium than TIVA.<br />Trial Registration: The study was registered on ClinicalTrials.gov (Identifier: NCT06597812) .<br /> (© 2024. The Author(s).)
- Subjects :
- Aged
Aged, 80 and over
Female
Humans
Male
Middle Aged
Anesthesia, Intravenous methods
Delirium epidemiology
Delirium prevention & control
Emergence Delirium epidemiology
Emergence Delirium prevention & control
Incidence
Postoperative Complications epidemiology
Postoperative Complications prevention & control
Prospective Studies
Anesthetics, Inhalation adverse effects
Anesthetics, Inhalation administration & dosage
Cholecystectomy, Laparoscopic methods
Sevoflurane administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1471-2253
- Volume :
- 24
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- BMC anesthesiology
- Publication Type :
- Academic Journal
- Accession number :
- 39354373
- Full Text :
- https://doi.org/10.1186/s12871-024-02735-y