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8. Gastrointestinal tolerance of erythritol-containing beverage in young children: a double-blind, randomised controlled trial

Author

Jacqz-Aigrain, E., Kassai, B., Cornu, C., Cazaubiel, J.-M., Housez, B., Cazaubiel, M., Prevel, J.-M., Bell, M., Boileau, A., and de Cock, P.

Subjects
Beverages -- Health aspects, Erythritol -- Health aspects, Gastrointestinal system -- Health aspects, Food/cooking/nutrition, Health
Abstract

BACKGROUND/OBJECTIVE: To determine gastrointestinal (GI) responses and maximum tolerated dose of erythritol in young children given as a single oral dose in a 250-ml non-carbonated fruit-flavoured beverage in between meals. This is a multicentre double-blind study with sequential design for multiple dose groups and randomised crossover for comparators of placebo vs dose. SUBJECTS/METHODS: A total of 185 healthy young children aged 4-6 years were recruited at three clinical investigation centres after informed consent of both parents; 184 children completed the study. Children were included in one of the four dose groups (5, 15, 20 or 25 g erythritol) and exposed randomly to only one single dose vs an isosweet sucrose placebo. After consumption in the clinic and an observation period, GI symptoms and stooling patterns were recorded during the next 48 h. RESULTS: Statistically significantly more episodes of diarrhoea and/or severe GI symptoms were observed in the 20 and 25 g groups compared with placebo, but not in the 5 and 15 g groups. Stool consistency, as measured by Bristol stool scale, was lower in the 15-, 20- and 25 g groups for the first 24-h period, but not at later time points. Incidences of nausea, vomiting, borborygmi, excess flatus and abdominal pain were not significantly different from the placebo controls at all doses of erythritol. CONCLUSIONS: Rapid ingestion of up to and including 15 g (6% w/v) of erythritol in a beverage in between meals by young children aged 4-6 years was well tolerated. The no observed effect level for diarrhoea and/or severe GI symptoms was 15 g (0.73 g/kg body weight (bw)). Children appeared not to be more sensitive to the GI effects of erythritol than published for adults on a g/kg bw basis. European Journal of Clinical Nutrition (2015) 69, 746-751; doi: 10.1038/ejcn.2015.4; published online 6 March 2015, INTRODUCTION Erythritol is a four-carbon polyol with a sweetness potency of ~ 70% compared with sucrose. It is present naturally in various fruits, fermented foods, mushrooms and cheese, and it [...]

Published
2015
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13. Factors associated with 12 week case-fatality in Staphylococcus aureus bacteraemia: a prospective cohort study

Author

Chirouze, Catherine, Curlier, Elodie, Descottes-Genon, Cécile, Hoen, Bruno, Patry, Isabelle, Vettoretti, Lucie, Chavanet, Pascal, Eicher, Jean-Christophe, Greusard, Marie-Christine, Neuwirth, Catherine, Péchinot, André, Piroth, Lionel, Célard, Marie, Cornu, Catherine, Delahaye, François, Hadid, Malika, Rausch, Pascale, Coma, Audrey, Galtier, Florence, Géraud, Philippe, Jean-Pierre, Hélène, Le Moing, Vincent, Sportouch, Catherine, Reynes, Jacques, Aissa, Nejla, Doco-Lecompte, Thanh, Goehringer, François, Keil, Nathalie, Letranchant, Lorraine, Malela, Hepher, May, Thierry, Selton-Suty, Christine, Bedos, Nathalie, Lavigne, Jean-Philippe, Lechiche, Catherine, Sotto, Albert, Duval, Xavier, Habensus, Emila Ilic, Iung, Bernard, Leport, Catherine, Longuet, Pascale, Ruimy, Raymond, Bellissant, Eric, Donnio, Pierre-Yves, Le Gac, Fabienne, Michelet, Christian, Revest, Matthieu, Tattevin, Pierre, Thebault, Elise, Alla, François, Braquet, Pierre, Erpelding, Marie-Line, Minary, Laetitia, Bès, Michèle, Etienne, Jérôme, Tristan, Anne, Vandenesch, François, Van Belkum, Alex, Vanwamel, Willem, Braquet, P., Alla, F., Cornu, C., Goehringer, F., Piroth, L., Chirouze, C., Revest, M., Lechiche, C., Duval, X., and Le Moing, V.

Published
2016
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29. Energy Expenditure in Older People Hospitalized for an Acute Episode

Author

Bonnefoy, M., Gilbert, T., Normand, S., Jauffret, M., Roy, P., Morio, B., Cornu, C., Roche, S., Laville, M., Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National de la Recherche Agronomique (INRA), Service de médecine gériatrique, centre hospitalier Lyon Sud, Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), Motricité, interactions, performance EA 4334 / Movement - Interactions - Performance (MIP), Le Mans Université (UM)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Université de Nantes - UFR des Sciences et Techniques des Activités Physiques et Sportives (UFR STAPS), Université de Nantes (UN)-Université de Nantes (UN), Catalan Institute of Nanoscience and Nanotechnology (ICN2), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC)-Barcelona Institute of Science and Technology (BIST), Institució Catalana de Recerca i Estudis Avançats (ICREA), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Biostatistiques [Lyon], Hospices Civils de Lyon (HCL), INRAE Transfert, CarMeN, laboratoire, Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Laboratoire Motricité, Interactions, Performance, Université de Nantes (UN), Consejo Superior de Investigaciones Científicas [Spain] (CSIC)-Barcelona Institute of Science and Technology (BIST), Université de Nantes - UFR des Sciences et Techniques des Activités Physiques et Sportives (UFR STAPS), and Université de Nantes (UN)-Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Le Mans Université (UM)

Subjects
Aged, 80 and over, Male, body composition, [SDV]Life Sciences [q-bio], Nutritional Requirements, Nutritional Status, Calorimetry, Indirect, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, frail elderly, Article, doubly labeled water, energy requirements, Hospitalization, [SDV] Life Sciences [q-bio], aged, Acute Disease, Weight Loss, energy expenditure, energy metabolism, [SDV.MHEP.AHA]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], Humans, Female, Energy Intake, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
Abstract

Weight loss and worsening of nutritional state is a frequent downfall of acute hospitalization in older people. It is usually accepted that acute inflammation is responsible for hypercatabolism. However, several studies suggest, on the contrary, a reduction in resting energy expenditure (REE). This study aimed to obtain a reliable measure of REE and total energy expenditure (TEE) in older patients hospitalized for an acute episode in order to better assess patients&rsquo, energy requirements and help understand the mechanisms of weight loss in this situation. Nineteen hospitalized older patients (mean age 83 years) with C-reactive protein (CRP) level &gt, 20mg/L were recruited. REE and TEE were measured using gold standard methods of indirect calorimetry and doubly labeled water (DLW), respectively. REE was then compared to data from a previous study on aged volunteers from nursing homes who were free of an acute stressor event. Energy requirements measured by DLW were confirmed at 1.3 &times, REE. Energy intake covered the needs but did not prevent weight loss in these patients. TEE was not increased in hospitalized patients and was not influenced by inflammation, while the relationship between REE and inflammation was uncertain. Our results suggest that lean mass remains the major determinant of REE in hospitalized older people and that weight loss may not be explained solely by a state of hypercatabolism.

Published
2019

41. Quality of qualitative studies centred on patients in family practice: a systematic review

Author

Eschalier, Benedicte, DESCAMPS, Stéphane, Pereira, Bruno, Vaillant-Roussel, Hélène, Girard, Guillaume, BOISGARD, Stéphane, Coudeyre, Emmanuel, Nazarian, Ara, Rehman, M., Tudrej, B.V., Soustre, J., Buisson, M., Archambault, P., Pouchain, D., Gueyffier, François, Faillie, J.-L., Perault-Pochat, C., Cornu, C., Boussageon, R., Cambon, Benoit, Vorilhon, Philippe, Michel, Laurence, Cadwallader, Jean-Sébastien, Aubin-Auger, Isabelle, Vaillant Roussel, Hélène, Département de Médecine Générale, Faculté de Médecine, Université Clermont Auvergne, Service d’Orthopédie Traumatologie [CHU Clermont-Ferrand], CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Biostatistiques, Inferential, Institut de Chimie de Clermont-Ferrand (ICCF), SIGMA Clermont (SIGMA Clermont)-Institut de Chimie du CNRS (INC)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), médecine physique et de réadaptation, CHU Clermont-Ferrand, Center for Advanced Orthopaedic Studies, Harvard Medical School [Boston] (HMS), Service de cardiologie [CHU de Poitiers], Centre hospitalier universitaire de Poitiers (CHU Poitiers), Université de Poitiers - Faculté de Médecine et de Pharmacie, Université de Poitiers, Virologie et pathogenèse virale (VPV), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Institut des Sciences de la MER de Rimouski (ISMER), Université du Québec à Rimouski (UQAR), Université de Tours (UT), Evaluation et modélisation des effets thérapeutiques, Département biostatistiques et modélisation pour la santé et l'environnement [LBBE], Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), CIC 1407, Hospices Civils de Lyon (HCL), CIC CHU Lyon (inserm), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de Médecine Générale [Clermont-Ferrand], Faculté de Médecine - Clermont-Auvergne (FM - UCA), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Université Sorbonne Paris Cité (USPC), Centre de recherche en épidémiologie et santé des populations (CESP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Recherche Clinique ville-hôpital, Méthodologies et Société (REMES), Université Paris Diderot - Paris 7 (UPD7), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), and Université de Tours

Subjects
Research design, medicine.medical_specialty, Biomedical Research, media_common.quotation_subject, Interviews as Topic, 03 medical and health sciences, 0302 clinical medicine, Medicine, Humans, Quality (business), Confidentiality, 030212 general & internal medicine, Research question, Qualitative Research, ComputingMilieux_MISCELLANEOUS, media_common, Data collection, Impact factor, business.industry, 030503 health policy & services, Focus Groups, Focus group, 3. Good health, Research Design, Family medicine, 0305 other medical science, business, Family Practice, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Qualitative research
Abstract

BACKGROUND Qualitative research is often used in the field of general medicine. Our objective was to evaluate the quality of published qualitative studies conducted using individual interviews or focus groups centred on patients monitored in general practice. METHODS We have undertaken a review of the literature in the PubMed and Embase databases of articles up to February 2014. The selection criteria were qualitative studies conducted using individual interviews or focus groups, centred on patients monitored in general practice. The articles chosen were analysed and evaluated using a score established from the Relevance, Appropriateness, Transparency and Soundness (RATS) grid. RESULTS The average score of the 52 studies chosen was 28 out of 42. The criteria least often present were the description of the patients who chose not to participate in the study, the justification of the end of data collection, the discussion of the influence of the researchers and the discussion of the confidentiality of the data. The criteria most frequently described were an explicit research question, justified and in relation to existing knowledge, the agreement of the ethical committee and the presence of quotations. The number of studies and the score increased from year-to-year. The score was independent of the impact factor of the journal. CONCLUSIONS Even though the qualitative research was published in reviews with a low impact factor, our results suggest that this research responded to the quality criteria of the RATS grid. The evaluation scored using RATS could be useful for authors or reviewers and for literature reviews.

Published
2016

42. Neuraxial analgesia is not associated with an increased risk of post-partum relapses in MS

Author

Lavie, Caroline, primary, Rollot, Fabien, additional, Durand-Dubief, Françoise, additional, Marignier, Romain, additional, Ionescu, Iuliana, additional, Casey, Romain, additional, Moreau, Thibault, additional, Tourniaire, Patricia, additional, Hutchinson, Michael, additional, D’Hooghe, Marie Béatrice, additional, Laplaud, David-Axel, additional, Clavelou, Pierre, additional, De Sèze, Jérôme, additional, Debouverie, Marc, additional, Brassat, David, additional, Pelletier, Jean, additional, Lebrun-Frenay, Christine, additional, Le Page, Emmanuelle, additional, Castelnovo, Giovanni, additional, Berger, Eric, additional, Hautecoeur, Patrick, additional, Heinzlef, Olivier, additional, Durelli, Luca, additional, Clerico, Marinella, additional, Trojano, Maria, additional, Patti, Francesco, additional, Vukusic, Sandra, additional, Alpérovitch, A., additional, Carton, H., additional, d’Hooghe, M.B., additional, Hommes, O., additional, Hutchinson, M., additional, Adeleine, P., additional, Biron, A., additional, Cortinovis-Tourniaire, P., additional, Grimaud, J., additional, Hours, M., additional, Moreau, T., additional, Vukusic, S., additional, Confavreux, C., additional, Chauplannaz, G., additional, Latombe, D., additional, Clanet, M., additional, Lau, G., additional, Rumbach, L., additional, Goas, J.Y., additional, Rouhart, F., additional, Mazingue, A., additional, Roullet, E., additional, Madigand, M., additional, Hautecoeur, P., additional, Brunet, P., additional, Edan, G., additional, Allaire, C., additional, Riffault, G., additional, Leche, J., additional, Benoit, T., additional, Simonin, C., additional, Ziegler, F., additional, Baron, J.C., additional, Rivrain, Y., additional, Dumas, R., additional, Loche, D., additional, Bourrin, J.C., additional, Huttin, B., additional, Delisse, B., additional, Gibert, I., additional, Boulay, C., additional, Verceletto, M., additional, Durand, G., additional, Bonneviot, G., additional, Gil, R., additional, Hedreville, M.A., additional, Belair, C., additional, Poitevin, R.J., additional, Devoize, J.L., additional, Wyremblewski, P., additional, Delestre, F., additional, Setiey, A., additional, Comi, G., additional, Filippi, M., additional, Ghezzi, A., additional, Martinelli, V., additional, Rossi, P., additional, Zaffaroni, M., additional, Tola, M.R., additional, Amato, M.P., additional, Fioretti, C., additional, Meucci, G., additional, Inglese, M., additional, Mancardi, G.L., additional, Gambi, D., additional, Thomas, A., additional, Cavazzuti, M., additional, Citterio, A., additional, Heltberg, A., additional, Hansen, H.J., additional, Fernandez, O., additional, Romero, F., additional, Arbizu, T., additional, Hernandez, J.J., additional, De Andres de Frutos, C., additional, Geffner Sclarky, D., additional, Aladro Benito, Y., additional, Reyes Yanes, P., additional, Aguilar, M, additional, Burguera, J.A., additional, Yaya, R., additional, Bonakim Dib, W., additional, Arzua-Mouronte, D., additional, Sindic, C.J.M., additional, Medaer, R., additional, Roose, H., additional, Geens, K.M.J., additional, Guillaume, D., additional, Van Zandycke, M., additional, Janssens, J., additional, Cornette, M., additional, Mol, L., additional, Weilbach, F., additional, Flachenecker, P., additional, Hartung, H.P., additional, Haas, J., additional, Tendolkar, I., additional, Sindrn, E., additional, Kölmel, H.W., additional, Reichel, D., additional, Rauch, M., additional, Preuss, S., additional, Poser, S., additional, Mauch, E., additional, Strausser-Fuchs, S., additional, Kolleger, H., additional, Hawkins, S., additional, Howell, S.J.L., additional, Rees, J.E., additional, Thompson, A., additional, Johnson, M., additional, Boggild, M., additional, Gregory, R.P., additional, Bates, D., additional, Bone, I., additional, Polman, C., additional, Frequin, S., additional, Jongen, P., additional, Correia de Sa, J., additional, Rio, M.E., additional, Huber, S., additional, Lechner-Scott, J., additional, Kappos, L., additional, Ionescu, I., additional, Cornu, C., additional, El-Etr, M., additional, Baulieu, E.E., additional, Schumacher, M, additional, Miller, D.H., additional, Pugeat, M., additional, d’Archangues, C., additional, Conard, J., additional, Ménard, J., additional, Sitruk-Ware, R., additional, Pelissier, C., additional, Dat, S., additional, Belaïsch-Allard, J., additional, Athéa, N., additional, Büschsenschutz, D., additional, Lyon-Caen, O., additional, Gonsette, R., additional, Boissel, J.P., additional, Ffrench, P., additional, Durand-Dubief, F., additional, Cotton, F., additional, Pachai, C., additional, Bracoud, L., additional, Androdias, G., additional, Marignier, R., additional, Laplaud, D.A., additional, Wiertlewski, S., additional, Lanctin-Garcia, C., additional, Couvreur, G., additional, Madinier, G., additional, Clavelou, P., additional, Taithe, F., additional, Aufauvre, D., additional, Guy, N., additional, Ferrier, A., additional, De Sèze, J., additional, Collongues, N., additional, Debouverie, M., additional, Viala, F., additional, Brassat, D., additional, Gerdelat-Mas, A., additional, Henry, P., additional, Pelletier, J., additional, Rico-Lamy, A., additional, Lebrun-Frenay, C., additional, Lepage, E., additional, Deburghraeve, V., additional, Castelnovo, G., additional, Berger, E., additional, Blondiau, M., additional, Heinzlef, O., additional, Coustans, M., additional, Clerc, C., additional, Rieu, L., additional, Lauxerois, M., additional, Hinzelin, G., additional, Ouallet, J.C., additional, Minier, D., additional, Vion, P., additional, Gromaire-Fayolle, N., additional, Derache, N., additional, Thouvenot, E., additional, Sallansonnet-Froment, M., additional, Tourniaire, P., additional, Toureille, L., additional, Borgel, F., additional, Stankoff, B., additional, Moroianu, C., additional, Guennoc, A.M., additional, Tournier-Gervason, C.L., additional, Peysson, S., additional, Trojano, M., additional, Patti, F., additional, D’Amico, E., additional, Motti, L., additional, Durelli, L., additional, and Tavella, A., additional

Published
2018
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45. Coussin de positionnement pour ponctions lombaires en oncohématologie pédiatrique: résultats d'un essai randomisé

Author

Cornu C, Rabilloud M, Kassaï B, Bissery A, Gaillard S, Aubert F, Matthias Schell, Perrine Marec-Berard, and Kebaïli K

Subjects
Gynecology, Cancer Research, medicine.medical_specialty, Oncology, business.industry, Medicine, Radiology, Nuclear Medicine and imaging, Hematology, General Medicine, business
Abstract

Les procedures invasives repetees en oncologie pediatrique posent des problemes de douleur, d'inconfort et d'anxiete pour les enfants. Les ponctions lombaires (PL) font partie de ces procedures particulierement frequentes. La douleur est relativement bien maitrisee, mais l'anxiete et l'apprehension restent un probleme. La bonne position de l'enfant est une condition essentielle a la reussite du geste et n'est pas toujours optimale chez un enfant: immobilite difficile a obtenir, mouvements de retrait, contention inappropriee. Un coussin de positionnement pour la realisation des PLs a ete mis au point. Il permet une flexion lombaire optimale en conservant un relâchement des muscles paravertebraux, ce qui facilite la rea-lisation des PLs chez des enfants conscients, sans sedation ou avec une sedation minimale. Nous presentons, ici, les resultats d'une etude randomisee dont le but etait d'evaluer le benefice du coussin sur la qualite technique du geste. Methodes. Les enfants de 2 a 18 ans devant subir une PL dans deux services d'oncohematologie pediatrique ont ete randomises en deux groupes: groupe avec coussin, groupe sans coussin. Le critere principal etait le taux de succes defini par un objectif atteint (prelevement et/ou injection) a la premiere tentative, sans hemorragie (moins de 50 hematies/mm 3 ). Les criteres secondaires etaient: la douleur de l'enfant autoevaluee a l'aide de l'echelle visuelle analogique (EVA) pour les enfants de plus de six ans, la douleur percue par les parents et les soignants, la satisfaction de l'enfant, des parents, des soignants et de l'operateur, la cooperation de l'enfant et la survenue d'un syndrome post-PL. Resultats. Cent vingt-quatre enfants (62 par groupe) ont ete inclus entre juillet 2004 et septembre 2006. L'analyse n'a pas permis de retrouver de difference significative entre les deux groupes. Cependant, tous les criteres etaient plus favorables dans le groupe coussin: taux de succes de 67 vs 57 % (p = 0,23) ; taux de syndromes post-PL de 15 vs 24 % (p = 0,17). Dans le sous-groupe des enfants de plus de six ans (n = 72), le taux de succes etait significativement plus eleve dans le groupe avec coussin (58,5 vs 41,5 % ; p = 0,031 ). Conclusions. Le coussin semble apporter un benefice significatif uniquement dans la population des enfants de plus de six ans. Pour les autres, cette etude n'a pas permis de mettre en evidence une difference significative. Une etude plus large est souhaitable. Le coussin est neanmoins utilise en routine dans les unites ou a eu lieu cette etude, et les soignants comme les enfants sont demandeurs de son utilisation.

Published
2009

49. Factors associated with 12 week case-fatality in Staphylococcus aureus bacteraemia: a prospective cohort study

Author

Braquet, P., primary, Alla, F., additional, Cornu, C., additional, Goehringer, F., additional, Piroth, L., additional, Chirouze, C., additional, Revest, M., additional, Lechiche, C., additional, Duval, X., additional, Le Moing, V., additional, Chirouze, Catherine, additional, Curlier, Elodie, additional, Descottes-Genon, Cécile, additional, Hoen, Bruno, additional, Patry, Isabelle, additional, Vettoretti, Lucie, additional, Chavanet, Pascal, additional, Eicher, Jean-Christophe, additional, Greusard, Marie-Christine, additional, Neuwirth, Catherine, additional, Péchinot, André, additional, Piroth, Lionel, additional, Célard, Marie, additional, Cornu, Catherine, additional, Delahaye, François, additional, Hadid, Malika, additional, Rausch, Pascale, additional, Coma, Audrey, additional, Galtier, Florence, additional, Géraud, Philippe, additional, Jean-Pierre, Hélène, additional, Le Moing, Vincent, additional, Sportouch, Catherine, additional, Reynes, Jacques, additional, Aissa, Nejla, additional, Doco-Lecompte, Thanh, additional, Goehringer, François, additional, Keil, Nathalie, additional, Letranchant, Lorraine, additional, Malela, Hepher, additional, May, Thierry, additional, Selton-Suty, Christine, additional, Bedos, Nathalie, additional, Lavigne, Jean-Philippe, additional, Lechiche, Catherine, additional, Sotto, Albert, additional, Duval, Xavier, additional, Habensus, Emila Ilic, additional, Iung, Bernard, additional, Leport, Catherine, additional, Longuet, Pascale, additional, Ruimy, Raymond, additional, Bellissant, Eric, additional, Donnio, Pierre-Yves, additional, Le Gac, Fabienne, additional, Michelet, Christian, additional, Revest, Matthieu, additional, Tattevin, Pierre, additional, Thebault, Elise, additional, Alla, François, additional, Braquet, Pierre, additional, Erpelding, Marie-Line, additional, Minary, Laetitia, additional, Bès, Michèle, additional, Etienne, Jérôme, additional, Tristan, Anne, additional, Vandenesch, François, additional, Van Belkum, Alex, additional, and Vanwamel, Willem, additional

Published
2016
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50. Time scales and pH dependence of the redox processes determining the photocatalytic efficiency of TiO2 nanoparticles from periodic illumination experiments in the stochastic regime

Author

Cornu, C. J. G., Colussi, A. J., and Hoffmann, M. R.

Subjects
Oxidation-reduction reaction -- Research, Voltage -- Research, Titanium dioxide -- Electric properties, Titanium dioxide -- Chemical properties, Chemistry, Physical and theoretical -- Research, Chemicals, plastics and rubber industries
Abstract

The photochemical experiments under periodic illumination in the stochastic regime reveals two rate-determining intermediates having different lifetimes with opposite pH dependences. The reducing species becomes more active at higher pH, the converse being valid for the oxygen carrier, as a result of the shift in the electrical potential of TiO2 particles.

Published
2003

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