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4. Early prolonged prone position in noninvasively ventilated patients with SARS-CoV-2-related moderate-to-severe hypoxemic respiratory failure: clinical outcomes and mechanisms for treatment response in the PRO-NIV study

Author

Musso, Giovanni, Taliano, Claudio, Molinaro, Federica, Fonti, Caterina, Veliaj, Deliana, Torti, Davide, Paschetta, Elena, Castagna, Elisabetta, Carbone, Giorgio, Laudari, Luigi, Aseglio, Claudio, Zocca, Edoardo, Chioni, Sonia, Giannone, Laura Ceretto, Arabia, Federica, Deiana, Cecilia, Benato, Francesca Maria, Druetta, Marta, Campagnola, Giorgio, Borsari, Margherita, Mucci, Martina, Rubatto, Tiziana, Peyronel, Mara, and Tirabassi, Gloria

Published
2022
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7. Highly Stable Under Irradiation Dlc Coatings for a New Class of Detectors: Structural and Morphological Features

Author

serra, antonio, primary, Caricato, Anna Paola, additional, manno, daniela, additional, Buccolieri, Alessandro, additional, Carbone, Giorgio Giuseppe, additional, Quarta, Gianluca, additional, Calcagnile, Lucio, additional, Martino, Maurizio, additional, Aziz, Muhammad Rizwan, additional, Pellecchia, Antonello, additional, and Verwilligen, Piet, additional

Published
2024
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9. Validation of the BAP-65 score for prediction of in-hospital death or use of mechanical ventilation in patients presenting to the emergency department with an acute exacerbation of COPD: a retrospective multi-center study from the Italian Society of Emergency Medicine (SIMEU)

Author

Adinolfi, Luigi Elio, Alvisi, Antonella, Antonio, Pagano, Azin, Giulia, Balloni, Andrea, Bandiera, Geminiano, Barchetti, Marco, Barillari, Alfredo, Barozzi, Marco, Belloni, Giulia, Belotti, Eugenia, Binetti, Nicola, Bonora, Miriam, Bruni, Rosamaria, Cacco, Silvia, Camisa, Daniele, Carbone, Giorgio, Carpinteri, Giuseppe, Catino, Laura, Cazzaniga, Massimo, Cenni, Patrizia, Chelli, Vittorio, Cicero, Leonora, Cottone, Carlo Domenico, Cuccia, Filippa, D'Angelo, Luciano, Dalmonte, Francesca, Daviddi, Fabio, De Vita, Anna, Famà, Fausto, Fedele, Marta, Fonti, Caterina, Frigerio, Marta, Gallingani, Alan, Ghiglione, Valeria, Gioffrè-Florio, Maria, Giordano, Mauro, Giostra, Fabrizio, Galli, Maria Giulia, Greggi, Maria Elena, Groff, Paolo, Guizzardi, Stefano, Lagasio, Chiara, Lazzara, Giuseppe, Lubini, Eloisa, Magni, Laura, Mancarella, Sandro, Mangano, Giuseppe, Maragno, Margherita, Menabue, Monia, Meoni, Eleonora, Molinaro, Federica, Morelli, Alice, Moscariello, Francesco, Nevola, Riccardo, Noto, Paola, Paladino, Fiorella, Pancani, Roberta, Petrelli, Giuseppina, Petrino, Roberta, Sinno, Carmine, Tafa, Aferdita, Tartaglia, Sergio, Taurino, Chiara, Treleani, Martina, Villari, Liliana, Vitelli, Alessandra, Zaccagni, Cinzia, Zaccaro, Bruna, Zacchino, Massimo, Germini, Federico, Veronese, Giacomo, Marcucci, Maura, Coen, Daniele, Ardemagni, Deborah, Montano, Nicola, and Fabbri, Andrea

Published
2019
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11. COPD exacerbations in the emergency department: Epidemiology and related costs. A retrospective cohort multicentre study from the Italian Society of Emergency Medicine (SIMEU)

Author

Adinolfi, Luigi Elio, Alvisi, Antonella, Azin, Giulia, Balloni, Andrea, Bandiera, Geminiano, Barchetti, Marco, Barillari, Alfredo, Barozzi, Marco, Belloni, Giulia, Belotti, Eugenia, Binetti, Nicola, Bonora, Miriam, Bruni, Rosamaria, Cacco, Silvia, Camisa, Daniele, Carbone, Giorgio, Carpinteri, Giuseppe, Catino, Laura, Cazzaniga, Massimo, Cenni, Patrizia, Chelli, Vittorio, Cicero, Leonora, Cottone, Carlo Domenico, Cuccia, Filippa, D'Angelo, Luciano, Dalmonte, Francesca, Daviddi, Fabio, De Vita, Anna, Famà, Fausto, Fedele, Marta, Fonti, Caterina, Frigerio, Marta, Gallingani, Alan, Ghiglione, Valeria, Gioffrè-Florio, Maria, Giordano, Mauro, Giostra, Fabrizio, Galli, Maria Giulia, Greggi, Maria Elena, Groff, Paolo, Guizzardi, Stefano, Lagasio, Chiara, Lazzara, Giuseppe, Lubini, Eloisa, Magni, Laura, Mancarella, Sandro, Mangano, Giuseppe, Maragno, Margherita, Menabue, Monia, Meoni, Eleonora, Molinaro, Federica, Morelli, Alice, Moscariello, Francesco, Nevola, Riccardo, Noto, Paola, Pagano, Antonio, Paladino, Fiorella, Pancani, Roberta, Petrelli, Giuseppina, Petrino, Roberta, Sinno, Carmine, Tafa, Aferdita, Tartaglia, Sergio, Taurino, Chiara, Treleani, Martina, Villari, Liliana, Vitelli, Alessandra, Zaccagni, Cinzia, Zaccaro, Bruna, Zacchino, Massimo, Germini, Federico, Veronese, Giacomo, Marcucci, Maura, Coen, Daniele, Ardemagni, Deborah, Montano, Nicola, and Fabbri, Andrea

Published
2018
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14. Theoretical Investigation of Inorganic Particulate Matter: The Case of Water Adsorption on a NaCl Particle Model Studied Using Grand Canonical Monte Carlo Simulations

Author

Rizza, F, Rovaletti, A, Carbone, G, Miyake, T, Greco, C, Cosentino, U, Rizza, Fabio, Rovaletti, Anna, Carbone, Giorgio, Miyake, Toshiko, Greco, Claudio, Cosentino, Ugo, Rizza, F, Rovaletti, A, Carbone, G, Miyake, T, Greco, C, Cosentino, U, Rizza, Fabio, Rovaletti, Anna, Carbone, Giorgio, Miyake, Toshiko, Greco, Claudio, and Cosentino, Ugo

Abstract

Sodium chloride (NaCl) represents the principal component of atmospheric particulates of marine origin. To gain a molecular-level understanding of the adsorption process of water vapor on the NaCl surface, Monte Carlo simulations performed in the Grand Canonical ensemble were carried out, considering the water adsorption at different water pressures on a NaCl(001) surface. The calculated adsorption isotherm shows four different regions, whose coverages correspond to those of the low-, transition-, high-, and pre-solution-coverage regions experimentally observed. Detailed analysis reveals how the structure of the adsorbed water molecules (islands, layer, and multi-layer) changes depending on water pressure, and how their orientation with respect to the surface varies with the distance from the surface. This detailed information further supports the picture coming from previous experimental IR absorption spectroscopy studies.

Published
2023

17. The emergency department arrival mode and its relations to ED management and 30-day mortality in acute heart failure: an ancillary analysis from the EURODEM study

Author

UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service des urgences, Harjola, Pia, Tarvasmäki, Tuukka, Barletta, Cinzia, Body, Richard, Capsec, Jean, Christ, Michael, Garcia-Castrillo, Luis, Golea, Adela, Karamercan, Mehmet A., Martin, Paul-Louis, Miró, Òscar, Tolonen, Jukka, van Meer, Oene, Palomäki, Ari, Verschuren, Franck, Harjola, Veli-Pekka, Laribi, Said, Plaisance, Patrick, Dandachi, Ghanima Al, Maignan, Maxime, Pateron, Dominique, Hermand, Christelle, Tessier, Cindy, Roy, Pierre-Marie, Bucco, Lucie, Duytsche, Nicolas, Garmilla, Pablo, Carbone, Giorgio, Cosentini, Roberto, Truță, Sorana, Hrihorișan, Natalia, Cimpoeșu, Diana, Rotaru, Luciana, Petrică, Alina, Cojocaru, Mariana, Nica, Silvia, Tudoran, Rodica, Vecerdi, Cristina, Puticiu, Monica, Schönberger, Titus, Coolsma, Constant, Baggelaar, Maarten, Fransen, Noortje, van den Brand, Crispijn, Idzenga, Doutsje, Maas, Maaike, Franssen, Myriam, Staal, Charlotte Mackaij, Schutte, Lot, de Kubber, Marije, Mignot-Evers, Lisette, Penninga-Puister, Ursula, Jansen, Joyce, Kuijten, Jeroen, Bouwhuis, Marna, Reuben, Adam, Smith, Jason, Ramlakhan, Shammi, Darwent, Melanie, Gagg, James, Keating, Liza, Bongale, Santosh, Hardy, Elaine, Keep, Jeff, Jarman, Heather, Crane, Steven, Lawal, Olakunle, Hassan, Taj, Corfield, Alasdair, Reed, Matthew, Geier, Felicitas, Smolarsky, Yvonne, Blaschke, Sabine, Kill, Clemens, Jerrentrup, Andreas, Hohenstein, Christian, Rockmann, Felix, Brünnler, Tanja, Ghuysen, Alexandre, Vranckx, Marc, Ergin, Mehmet, Dundar, Zerrin D., Altuncu, Yusuf A., Arziman, Ibrahim, Avcil, Mucahit, Katirci, Yavuz, Suurmunne, Hanna, Kokkonen, Liisa, Valli, Juha, Kiljunen, Minna, Kaye, Sanna, Mäkelä, Mikko, Metsäniitty, Juhani, Vaula, Eija, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service des urgences, Harjola, Pia, Tarvasmäki, Tuukka, Barletta, Cinzia, Body, Richard, Capsec, Jean, Christ, Michael, Garcia-Castrillo, Luis, Golea, Adela, Karamercan, Mehmet A., Martin, Paul-Louis, Miró, Òscar, Tolonen, Jukka, van Meer, Oene, Palomäki, Ari, Verschuren, Franck, Harjola, Veli-Pekka, Laribi, Said, Plaisance, Patrick, Dandachi, Ghanima Al, Maignan, Maxime, Pateron, Dominique, Hermand, Christelle, Tessier, Cindy, Roy, Pierre-Marie, Bucco, Lucie, Duytsche, Nicolas, Garmilla, Pablo, Carbone, Giorgio, Cosentini, Roberto, Truță, Sorana, Hrihorișan, Natalia, Cimpoeșu, Diana, Rotaru, Luciana, Petrică, Alina, Cojocaru, Mariana, Nica, Silvia, Tudoran, Rodica, Vecerdi, Cristina, Puticiu, Monica, Schönberger, Titus, Coolsma, Constant, Baggelaar, Maarten, Fransen, Noortje, van den Brand, Crispijn, Idzenga, Doutsje, Maas, Maaike, Franssen, Myriam, Staal, Charlotte Mackaij, Schutte, Lot, de Kubber, Marije, Mignot-Evers, Lisette, Penninga-Puister, Ursula, Jansen, Joyce, Kuijten, Jeroen, Bouwhuis, Marna, Reuben, Adam, Smith, Jason, Ramlakhan, Shammi, Darwent, Melanie, Gagg, James, Keating, Liza, Bongale, Santosh, Hardy, Elaine, Keep, Jeff, Jarman, Heather, Crane, Steven, Lawal, Olakunle, Hassan, Taj, Corfield, Alasdair, Reed, Matthew, Geier, Felicitas, Smolarsky, Yvonne, Blaschke, Sabine, Kill, Clemens, Jerrentrup, Andreas, Hohenstein, Christian, Rockmann, Felix, Brünnler, Tanja, Ghuysen, Alexandre, Vranckx, Marc, Ergin, Mehmet, Dundar, Zerrin D., Altuncu, Yusuf A., Arziman, Ibrahim, Avcil, Mucahit, Katirci, Yavuz, Suurmunne, Hanna, Kokkonen, Liisa, Valli, Juha, Kiljunen, Minna, Kaye, Sanna, Mäkelä, Mikko, Metsäniitty, Juhani, and Vaula, Eija

Abstract

Background Acute heart failure patients are often encountered in emergency departments (ED) from 11% to 57% using emergency medical services (EMS). Our aim was to evaluate the association of EMS use with acute heart failure patients’ ED management and short-term outcomes. Methods This was a sub-analysis of a European EURODEM study. Data on patients presenting with dyspnoea were collected prospectively from European EDs. Patients with ED diagnosis of acute heart failure were categorized into two groups: those using EMS and those self-presenting (non- EMS). The independent association between EMS use and 30-day mortality was evaluated with logistic regression. Results Of the 500 acute heart failure patients, with information about the arrival mode to the ED, 309 (61.8%) arrived by EMS. These patients were older (median age 80 vs. 75 years, p < 0.001), more often female (56.4% vs. 42.1%, p = 0.002) and had more dementia (18.7% vs. 7.2%, p < 0.001). On admission, EMS patients had more often confusion (14.2% vs. 2.1%, p < 0.001) and higher respiratory rate (24/min vs. 21/min, p = 0.014; respiratory rate > 30/min in 17.1% patients vs. 7.5%, p = 0.005). The only difference in ED management appeared in the use of ventilatory support: 78.3% of EMS patients vs. 67.5% of non- EMS patients received supplementary oxygen (p = 0.007), and non-invasive ventilation was administered to 12.5% of EMS patients vs. 4.2% non- EMS patients (p = 0.002). EMS patients were more often hospitalized (82.4% vs. 65.9%, p < 0.001), had higher in-hospital mortality (8.7% vs. 3.1%, p = 0.014) and 30-day mortality (14.3% vs. 4.9%, p < 0.001). The use of EMS was an independent predictor of 30-day mortality (OR = 2.54, 95% CI 1.11–5.81, p = 0.027). Conclusion Most acute heart failure patients arrive at ED by EMS. These patients suffer from more severe respiratory distress and receive more often ventilatory support. EMS use is an independent predictor of 30-day mortality.

Published
2022

18. The emergency department arrival mode and its relations to ED management and 30-day mortality in acute heart failure:an ancillary analysis from the EURODEM study

Author

Harjola, Pia, Tarvasmäki, Tuukka, Barletta, Cinzia, Body, Richard, Capsec, Jean, Christ, Michael, Garcia-Castrillo, Luis, Golea, Adela, Karamercan, Mehmet A., Martin, Paul Louis, Miró, Òscar, Tolonen, Jukka, van Meer, Oene, Palomäki, Ari, Verschuren, Franck, Harjola, Veli Pekka, Laribi, Said, Plaisance, Patrick, Dandachi, Ghanima Al, Maignan, Maxime, Pateron, Dominique, Hermand, Christelle, Tessier, Cindy, Roy, Pierre Marie, Bucco, Lucie, Duytsche, Nicolas, Garmilla, Pablo, Carbone, Giorgio, Cosentini, Roberto, Truță, Sorana, Hrihorișan, Natalia, Cimpoeșu, Diana, Rotaru, Luciana, Petrica, Alina, Cojocaru, Mariana, Nica, Silvia, Tudoran, Rodica, Vecerdi, Cristina, Puticiu, Monica, Schönberger, Titus, Coolsma, Constant, Baggelaar, Maarten, Fransen, Noortje, van den Brand, Crispijn, Idzenga, Doutsje, Maas, Maaike, Franssen, Myriam, Staal, Charlotte Mackaij, Jansen, Joyce, Bouwhuis, Marna, Harjola, Pia, Tarvasmäki, Tuukka, Barletta, Cinzia, Body, Richard, Capsec, Jean, Christ, Michael, Garcia-Castrillo, Luis, Golea, Adela, Karamercan, Mehmet A., Martin, Paul Louis, Miró, Òscar, Tolonen, Jukka, van Meer, Oene, Palomäki, Ari, Verschuren, Franck, Harjola, Veli Pekka, Laribi, Said, Plaisance, Patrick, Dandachi, Ghanima Al, Maignan, Maxime, Pateron, Dominique, Hermand, Christelle, Tessier, Cindy, Roy, Pierre Marie, Bucco, Lucie, Duytsche, Nicolas, Garmilla, Pablo, Carbone, Giorgio, Cosentini, Roberto, Truță, Sorana, Hrihorișan, Natalia, Cimpoeșu, Diana, Rotaru, Luciana, Petrica, Alina, Cojocaru, Mariana, Nica, Silvia, Tudoran, Rodica, Vecerdi, Cristina, Puticiu, Monica, Schönberger, Titus, Coolsma, Constant, Baggelaar, Maarten, Fransen, Noortje, van den Brand, Crispijn, Idzenga, Doutsje, Maas, Maaike, Franssen, Myriam, Staal, Charlotte Mackaij, Jansen, Joyce, and Bouwhuis, Marna

Abstract

Background: Acute heart failure patients are often encountered in emergency departments (ED) from 11% to 57% using emergency medical services (EMS). Our aim was to evaluate the association of EMS use with acute heart failure patients’ ED management and short-term outcomes. Methods: This was a sub-analysis of a European EURODEM study. Data on patients presenting with dyspnoea were collected prospectively from European EDs. Patients with ED diagnosis of acute heart failure were categorized into two groups: those using EMS and those self-presenting (non- EMS). The independent association between EMS use and 30-day mortality was evaluated with logistic regression. Results: Of the 500 acute heart failure patients, with information about the arrival mode to the ED, 309 (61.8%) arrived by EMS. These patients were older (median age 80 vs. 75 years, p < 0.001), more often female (56.4% vs. 42.1%, p = 0.002) and had more dementia (18.7% vs. 7.2%, p < 0.001). On admission, EMS patients had more often confusion (14.2% vs. 2.1%, p < 0.001) and higher respiratory rate (24/min vs. 21/min, p = 0.014; respiratory rate > 30/min in 17.1% patients vs. 7.5%, p = 0.005). The only difference in ED management appeared in the use of ventilatory support: 78.3% of EMS patients vs. 67.5% of non- EMS patients received supplementary oxygen (p = 0.007), and non-invasive ventilation was administered to 12.5% of EMS patients vs. 4.2% non- EMS patients (p = 0.002). EMS patients were more often hospitalized (82.4% vs. 65.9%, p < 0.001), had higher in-hospital mortality (8.7% vs. 3.1%, p = 0.014) and 30-day mortality (14.3% vs. 4.9%, p < 0.001). The use of EMS was an independent predictor of 30-day mortality (OR = 2.54, 95% CI 1.11–5.81, p = 0.027). Conclusion: Most acute heart failure patients arrive at ED by EMS. These patients suffer from more severe respiratory distress and receive more often ventilatory support. EMS use is an independent predictor of 30-day mortality.

Published
2022

19. The emergency department arrival mode and its relations to ED management and 30-day mortality in acute heart failure

Author

Harjola, Pia, Tarvasmäki, Tuukka, Barletta, Cinzia, Body, Richard, Capsec, Jean, Christ, Michael, Garcia-Castrillo, Luis, Golea, Adela, Karamercan, Mehmet A., Martin, Paul-Louis, Miró, Òscar, Tolonen, Jukka, van Meer, Oene, Palomäki, Ari, Verschuren, Franck, Harjola, Veli-Pekka, Laribi, Said, Plaisance, Patrick, Dandachi, Ghanima Al, Maignan, Maxime, Pateron, Dominique, Hermand, Christelle, Tessier, Cindy, Roy, Pierre-Marie, Bucco, Lucie, Duytsche, Nicolas, Garmilla, Pablo, Carbone, Giorgio, Cosentini, Roberto, Truță, Sorana, Hrihorișan, Natalia, Cimpoeșu, Diana, Rotaru, Luciana, Petrică, Alina, Cojocaru, Mariana, Nica, Silvia, Tudoran, Rodica, Vecerdi, Cristina, Puticiu, Monica, Schönberger, Titus, Coolsma, Constant, Baggelaar, Maarten, Fransen, Noortje, van den Brand, Crispijn, Idzenga, Doutsje, Maas, Maaike, Franssen, Myriam, Staal, Charlotte Mackaij, Schutte, Lot, de Kubber, Marije, Mignot-Evers, Lisette, Penninga-Puister, Ursula, Jansen, Joyce, Kuijten, Jeroen, Bouwhuis, Marna, Reuben, Adam, Smith, Jason, Ramlakhan, Shammi, Darwent, Melanie, Gagg, James, Keating, Liza, Bongale, Santosh, Hardy, Elaine, Keep, Jeff, Jarman, Heather, Crane, Steven, Lawal, Olakunle, Hassan, Taj, Corfield, Alasdair, Reed, Matthew, Geier, Felicitas, Smolarsky, Yvonne, Blaschke, Sabine, Kill, Clemens, Jerrentrup, Andreas, Hohenstein, Christian, Rockmann, Felix, Brünnler, Tanja, Ghuysen, Alexandre, Vranckx, Marc, Ergin, Mehmet, Dundar, Zerrin D., Altuncu, Yusuf A., Arziman, Ibrahim, Avcil, Mucahit, Katirci, Yavuz, Suurmunne, Hanna, Kokkonen, Liisa, Valli, Juha, Kiljunen, Minna, Kaye, Sanna, Mäkelä, Mikko, Metsäniitty, Juhani, Vaula, Eija, Tampere University, Kanta-Häme Central Hospital Hämeenlinna, Clinical Medicine, Emergency Medicine, Research & Education, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service des urgences, HUS Emergency Medicine and Services, Department of Diagnostics and Therapeutics, HUS Heart and Lung Center, Clinicum, Kardiologian yksikkö, HUS Internal Medicine and Rehabilitation, Department of Medicine, HYKS erva, Päijät-Häme Welfare Consortium, and HUS Helsinki and Uusimaa Hospital District

Subjects
Arrival mode, Emergency Medical Services, EUROBSERVATIONAL RESEARCH-PROGRAM, DIAGNOSIS, Patient Admission, IN-HOSPITAL MORTALITY, PILOT, Humans, ESC GUIDELINES, Hospital Mortality, PREDICTORS, Aged, 80 and over, Heart Failure, Emergency medical services, OUTCOMES, Acute heart failure, ASSOCIATION, CARE, Prognosis, 3126 Surgery, anesthesiology, intensive care, radiology, EUROPEAN-SOCIETY, Management, Ventilatory support, Emergency Medicine, Female, Emergency Service, Hospital
Abstract

Background Acute heart failure patients are often encountered in emergency departments (ED) from 11% to 57% using emergency medical services (EMS). Our aim was to evaluate the association of EMS use with acute heart failure patients’ ED management and short-term outcomes. Methods This was a sub-analysis of a European EURODEM study. Data on patients presenting with dyspnoea were collected prospectively from European EDs. Patients with ED diagnosis of acute heart failure were categorized into two groups: those using EMS and those self-presenting (non- EMS). The independent association between EMS use and 30-day mortality was evaluated with logistic regression. Results Of the 500 acute heart failure patients, with information about the arrival mode to the ED, 309 (61.8%) arrived by EMS. These patients were older (median age 80 vs. 75 years, p p = 0.002) and had more dementia (18.7% vs. 7.2%, p p p = 0.014; respiratory rate > 30/min in 17.1% patients vs. 7.5%, p = 0.005). The only difference in ED management appeared in the use of ventilatory support: 78.3% of EMS patients vs. 67.5% of non- EMS patients received supplementary oxygen (p = 0.007), and non-invasive ventilation was administered to 12.5% of EMS patients vs. 4.2% non- EMS patients (p = 0.002). EMS patients were more often hospitalized (82.4% vs. 65.9%, p p = 0.014) and 30-day mortality (14.3% vs. 4.9%, p p = 0.027). Conclusion Most acute heart failure patients arrive at ED by EMS. These patients suffer from more severe respiratory distress and receive more often ventilatory support. EMS use is an independent predictor of 30-day mortality.

Published
2022

20. Additional file 2 of Early prolonged prone position in noninvasively ventilated patients with SARS-CoV-2-related moderate-to-severe hypoxemic respiratory failure: clinical outcomes and mechanisms for treatment response in the PRO-NIV study

Author

Musso, Giovanni, Taliano, Claudio, Molinaro, Federica, Fonti, Caterina, Veliaj, Deliana, Torti, Davide, Paschetta, Elena, Castagna, Elisabetta, Carbone, Giorgio, Laudari, Luigi, Aseglio, Claudio, Zocca, Edoardo, Chioni, Sonia, Giannone, Laura Ceretto, Arabia, Federica, Deiana, Cecilia, Benato, Francesca Maria, Druetta, Marta, Campagnola, Giorgio, Borsari, Margherita, Mucci, Martina, Rubatto, Tiziana, Peyronel, Mara, and Tirabassi, Gloria

Subjects
InformationSystems_INFORMATIONSTORAGEANDRETRIEVAL, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, ComputingMilieux_COMPUTERSANDEDUCATION, Data_FILES, ComputerApplications_COMPUTERSINOTHERSYSTEMS
Abstract

Additional file 2: Supplementary Tables.

Published
2022
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21. Additional file 3 of Early prolonged prone position in noninvasively ventilated patients with SARS-CoV-2-related moderate-to-severe hypoxemic respiratory failure: clinical outcomes and mechanisms for treatment response in the PRO-NIV study

Author

Musso, Giovanni, Taliano, Claudio, Molinaro, Federica, Fonti, Caterina, Veliaj, Deliana, Torti, Davide, Paschetta, Elena, Castagna, Elisabetta, Carbone, Giorgio, Laudari, Luigi, Aseglio, Claudio, Zocca, Edoardo, Chioni, Sonia, Giannone, Laura Ceretto, Arabia, Federica, Deiana, Cecilia, Benato, Francesca Maria, Druetta, Marta, Campagnola, Giorgio, Borsari, Margherita, Mucci, Martina, Rubatto, Tiziana, Peyronel, Mara, and Tirabassi, Gloria

Subjects
InformationSystems_INFORMATIONSTORAGEANDRETRIEVAL, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, ComputingMilieux_COMPUTERSANDEDUCATION, Data_FILES, ComputerApplications_COMPUTERSINOTHERSYSTEMS
Abstract

Additional file 3: Supplementary protocol.

Published
2022
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22. Additional file 1 of Early prolonged prone position in noninvasively ventilated patients with SARS-CoV-2-related moderate-to-severe hypoxemic respiratory failure: clinical outcomes and mechanisms for treatment response in the PRO-NIV study

Author

Musso, Giovanni, Taliano, Claudio, Molinaro, Federica, Fonti, Caterina, Veliaj, Deliana, Torti, Davide, Paschetta, Elena, Castagna, Elisabetta, Carbone, Giorgio, Laudari, Luigi, Aseglio, Claudio, Zocca, Edoardo, Chioni, Sonia, Giannone, Laura Ceretto, Arabia, Federica, Deiana, Cecilia, Benato, Francesca Maria, Druetta, Marta, Campagnola, Giorgio, Borsari, Margherita, Mucci, Martina, Rubatto, Tiziana, Peyronel, Mara, and Tirabassi, Gloria

Abstract

Additional file 1: Supplementary Figures.

Published
2022
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36. Get with the guidelines: management of chronic obstructive pulmonary disease in emergency departments in Europe and Australasia is sub-optimal

Author

Van Meer, Oene, Keijzers, Gerben, Motiejunaite, Justina, Klim, Sharon, Capsec, Jean, Kuan, Win, McNulty, Richard, Tan, Clifford, Cowell, David Lord, Holdgate, Anna, Jain, Nitin, Devillecourt, Tracey, Forrester, Alan, Lee, Kendall, Chalkley, Dane, Gillett, Mark, Lozzi, Lydia, Asha, Stephen, Duffy, Martin, Watkins, Gina, Stone, Richard, Rosengren, David, Thone, Jae, Martin, Shane, Orda, Ulrich, Thom, Ogilvie, Kinnear, Frances, Eley, Rob, Ryan, Alison, Morel, Douglas, May, Christopher, Furyk, Jeremy, Thomson, Graeme, Smith, Simon, Smith, Richard, Maclean, Andrew, Grummisch, Michelle, Meyer, Alistair, Meek, Robert, Rosengarten, Pamela, Chan, Barry, Haythorne, Helen, Archer, Peter, Craig, Simon, Wilson, Kathryn, Knott, Jonathan, Ritchie, Peter, Bryant, Michael, MacDonald, Stephen, Lee, Tom, Mahlangu, Mlungisi, Mountain, David, Rogers, Ian, Otto, Tobias, Stuart, Peter, Bament, Jason, Brown, Michelle, Jones, Peter, Greven‐Garcia, Renee, Scott, Michael, Cheri, Thomas, Nguyen, Mai, Graham, Colin, Wong, Chi‐Pang, Wong, Tai Wai, Leung, Ling‐Pong, Man, Chan Ka, Saiboon, Ismail Mohd, Rahman, Nik Hisamuddin, Lee, Wee Yee, Lee, Francis Chun Yue, Kuan, Win Sen, Russell, SharonKerrie, Kelly, Anne‐Maree, Laribi, Gerbenand Said, Lawoko, Charles, Laribi, Said, Meer, Oene, Harjola, Veli‐Pekka, Golea, Adela, Christ, Michael, Garcia‐Castrillo, Luis, Al Dandachi, Ghanima, Maignan, Maxime, Hermand, DominiqueChristelle, Tessier, Cindy, Roy, Pierre‐Marie, Bucco, Lucie, Barletta, Cinzia, Carbone, Giorgio, Cosentini, Roberto, Truță, Sorana, Hrihorișan, Natalia, Cimpoeșu, Diana, Rotaru, Luciana, Petrică, Alina, Cojocaru, Mariana, Nica, Silvia, Tudoran, Rodica, Vecerdi, Cristina, Puticiu, Monica, Schönberger, Titus, Coolsma, Constant, Baggelaar, Maarten, Fransen, Noortje, Brand, Crispijn, Idzenga, Doutsje, Maas, Maaike, Franssen, Myriam, Mackaij‐Staal, Charlotte, Schutte, Lot, Kubber, Marije, Mignot‐Evers, Lisette, Penninga‐Puister, Ursula, Jansen, Joyce, Kuijten, Jeroen, Bouwhuis, Marna, Body, Richard, Reuben, Adam, Smith, Jason, Ramlakhan, Shammi, Darwent, Melanie, Gagg, James, Keating, Liza, Bongale, Santosh, Hardy, Elaine, Keep, Jeff, Jarman, Heather, Crane, Steven, Lawal, Olakunle, Hassan, Taj, Corfield, Alasdair, Reed, Matthew, Smolarsky, Yvonne, Blaschke, Sabine, Jerrentrup, ClemensAndreas, Hohenstein, Christian, Brünnler, FelixTanja, Ghuysen, Alexandre, Vranckx, Marc, Verschuren, Franck, Karamercan, Mehmet, Ergin, Mehmet, Dundar, Zerrin, Altuncu, Yusuf, Arziman, Ibrahim, Avcil, Mucahit, Katirci, Yavuz, Kokkonen, Liisa, Valli, JukkaJuha, Kiljunen, Minna, Tolonen, Jukka, Kaye, Sanna, Mäkelä, JukkaMikko, Metsäniitty, JukkaJuhani, Vaula, Eija, Duytsche, Nicolas, Garmilla, Pablo, HUS Emergency Medicine and Services, Department of Diagnostics and Therapeutics, University of Helsinki, Biomarqueurs CArdioNeuroVASCulaires (BioCANVAS), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Indian Institute of Technology Kharagpur (IIT Kharagpur), University of Leicester, Smith Watkins Trumpets, Institute for Fiscal Studies, Leibniz Institute for Tropospheric Research (TROPOS), University of California [Santa Barbara] (UCSB), University of California, iThemba Laboratory for Accelerator Based Science, Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Centre Hospitalier Universitaire [Grenoble] (CHU), Emergency Department (FV - ED), and Saint Luc University Hospital

Subjects
Male, medicine.medical_specialty, emergency department, [SDV]Life Sciences [q-bio], medicine.medical_treatment, 030204 cardiovascular system & hematology, ACUTE EXACERBATIONS, Pulmonary Disease, Chronic Obstructive, 03 medical and health sciences, 0302 clinical medicine, Dyspnoea, Internal Medicine, medicine, COPD, Humans, Prospective Studies, 030212 general & internal medicine, PREDICTORS, Prospective cohort study, Emergency Treatment, ComputingMilieux_MISCELLANEOUS, Aged, Aged, 80 and over, Mechanical ventilation, ASIA, Australasia, business.industry, NEW-ZEALAND DYSPNEA, Emergency department, Guideline, Middle Aged, medicine.disease, 3. Good health, Europe, Respiratory acidosis, 3121 General medicine, internal medicine and other clinical medicine, Practice Guidelines as Topic, Emergency medicine, outcome, Breathing, Female, Observational study, Emergency Service, Hospital, business, management
Abstract

OBJECTIVES: Exacerbations of chronic obstructive pulmonary disease (COPD) are common in emergency departments (ED). Guidelines recommend administration of inhaled bronchodilators, systemic corticosteroids and antibiotics along with non-invasive ventilation (NIV) for patients with respiratory acidosis. We aimed to determine compliance with guideline recommendations for patients with treated for COPD in ED in Europe (EUR) and South East Asia/Australasia (SEA) and to compare management and outcomes. METHODS: In each region, an observational prospective cohort study was performed that included patients presenting to EDs with the main complaint of dyspnoea during three 72-hour periods. This planned sub-study included those with an ED primary discharge diagnosis of COPD. Data were collected on demographics, clinical features, treatment, disposition and in-hospital mortality. We determined overall compliance with guideline recommendations and compared treatments and outcome between regions. RESULTS: 801 patients were included from 122 EDs (66 EUR and 46 SEA). Inhaled bronchodilators were administered to 80.3% of patients, systemic corticosteroids to 59.5%, antibiotics to 44% and 60.6% of patients with pH

Published
2020

39. Hydrogen peroxide LSPR sensing with unoxidised CuNPs-Tween® 60.

Author

Carbone, Giorgio Giuseppe, Manno, Daniela, Serra, Antonio, and Buccolieri, Alessandro

Subjects
*HYDROGEN peroxide, *PRECIOUS metals, *DETECTION limit, *POLYETHYLENE glycol, *AQUEOUS solutions
Abstract

Copper nanoparticles (CuNPs) as well as those of other noble metals show unique features that are not observed in bulk copper. Despite the enormous potential of CuNPs, their use is limited by their susceptibility to oxidation during and after synthesis. Here, an innovative method based on wet synthesis protocol was developed to produce an aqueous colloidal solution of CuNPs capped with Tween® 60 (Polyoxyethylene sorbitan monostearate) capable of being stable and non-oxidised for several months. The CuNPs colloidal solution was tested for the detection of hydrogen peroxide (H2O2) showing a detection limit of 10–11 M. This result may provide the basis for the design of a rapid, practical, and easy-to-use colorimetric sensor to detect H2O2 in the future. [ABSTRACT FROM AUTHOR]

Published
2022
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43. Validation of the BAP-65 score for prediction of in-hospital death or use of mechanical ventilation in patients presenting to the emergency department with an acute exacerbation of COPD: a retrospective multi-center study from the Italian Society of Emergency Medicine (SIMEU)

Author

Germini, Federico, primary, Veronese, Giacomo, additional, Marcucci, Maura, additional, Coen, Daniele, additional, Ardemagni, Deborah, additional, Montano, Nicola, additional, Fabbri, Andrea, additional, Adinolfi, Luigi Elio, additional, Alvisi, Antonella, additional, Antonio, Pagano, additional, Azin, Giulia, additional, Balloni, Andrea, additional, Bandiera, Geminiano, additional, Barchetti, Marco, additional, Barillari, Alfredo, additional, Barozzi, Marco, additional, Belloni, Giulia, additional, Belotti, Eugenia, additional, Binetti, Nicola, additional, Bonora, Miriam, additional, Bruni, Rosamaria, additional, Cacco, Silvia, additional, Camisa, Daniele, additional, Carbone, Giorgio, additional, Carpinteri, Giuseppe, additional, Catino, Laura, additional, Cazzaniga, Massimo, additional, Cenni, Patrizia, additional, Chelli, Vittorio, additional, Cicero, Leonora, additional, Cottone, Carlo Domenico, additional, Cuccia, Filippa, additional, D'Angelo, Luciano, additional, Dalmonte, Francesca, additional, Daviddi, Fabio, additional, De Vita, Anna, additional, Famà, Fausto, additional, Fedele, Marta, additional, Fonti, Caterina, additional, Frigerio, Marta, additional, Gallingani, Alan, additional, Ghiglione, Valeria, additional, Gioffrè-Florio, Maria, additional, Giordano, Mauro, additional, Giostra, Fabrizio, additional, Galli, Maria Giulia, additional, Greggi, Maria Elena, additional, Groff, Paolo, additional, Guizzardi, Stefano, additional, Lagasio, Chiara, additional, Lazzara, Giuseppe, additional, Lubini, Eloisa, additional, Magni, Laura, additional, Mancarella, Sandro, additional, Mangano, Giuseppe, additional, Maragno, Margherita, additional, Menabue, Monia, additional, Meoni, Eleonora, additional, Molinaro, Federica, additional, Morelli, Alice, additional, Moscariello, Francesco, additional, Nevola, Riccardo, additional, Noto, Paola, additional, Paladino, Fiorella, additional, Pancani, Roberta, additional, Petrelli, Giuseppina, additional, Petrino, Roberta, additional, Sinno, Carmine, additional, Tafa, Aferdita, additional, Tartaglia, Sergio, additional, Taurino, Chiara, additional, Treleani, Martina, additional, Villari, Liliana, additional, Vitelli, Alessandra, additional, Zaccagni, Cinzia, additional, Zaccaro, Bruna, additional, and Zacchino, Massimo, additional

Published
2019
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44. COPD exacerbations in the emergency department: Epidemiology and related costs. A retrospective cohort multicentre study from the Italian Society of Emergency Medicine (SIMEU)

Author

Germini, Federico, primary, Veronese, Giacomo, additional, Marcucci, Maura, additional, Coen, Daniele, additional, Ardemagni, Deborah, additional, Montano, Nicola, additional, Fabbri, Andrea, additional, Adinolfi, Luigi Elio, additional, Alvisi, Antonella, additional, Azin, Giulia, additional, Balloni, Andrea, additional, Bandiera, Geminiano, additional, Barchetti, Marco, additional, Barillari, Alfredo, additional, Barozzi, Marco, additional, Belloni, Giulia, additional, Belotti, Eugenia, additional, Binetti, Nicola, additional, Bonora, Miriam, additional, Bruni, Rosamaria, additional, Cacco, Silvia, additional, Camisa, Daniele, additional, Carbone, Giorgio, additional, Carpinteri, Giuseppe, additional, Catino, Laura, additional, Cazzaniga, Massimo, additional, Cenni, Patrizia, additional, Chelli, Vittorio, additional, Cicero, Leonora, additional, Cottone, Carlo Domenico, additional, Cuccia, Filippa, additional, D'Angelo, Luciano, additional, Dalmonte, Francesca, additional, Daviddi, Fabio, additional, De Vita, Anna, additional, Famà, Fausto, additional, Fedele, Marta, additional, Fonti, Caterina, additional, Frigerio, Marta, additional, Gallingani, Alan, additional, Ghiglione, Valeria, additional, Gioffrè-Florio, Maria, additional, Giordano, Mauro, additional, Giostra, Fabrizio, additional, Galli, Maria Giulia, additional, Greggi, Maria Elena, additional, Groff, Paolo, additional, Guizzardi, Stefano, additional, Lagasio, Chiara, additional, Lazzara, Giuseppe, additional, Lubini, Eloisa, additional, Magni, Laura, additional, Mancarella, Sandro, additional, Mangano, Giuseppe, additional, Maragno, Margherita, additional, Menabue, Monia, additional, Meoni, Eleonora, additional, Molinaro, Federica, additional, Morelli, Alice, additional, Moscariello, Francesco, additional, Nevola, Riccardo, additional, Noto, Paola, additional, Pagano, Antonio, additional, Paladino, Fiorella, additional, Pancani, Roberta, additional, Petrelli, Giuseppina, additional, Petrino, Roberta, additional, Sinno, Carmine, additional, Tafa, Aferdita, additional, Tartaglia, Sergio, additional, Taurino, Chiara, additional, Treleani, Martina, additional, Villari, Liliana, additional, Vitelli, Alessandra, additional, Zaccagni, Cinzia, additional, Zaccaro, Bruna, additional, and Zacchino, Massimo, additional

Published
2018
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45. Asymmetric deprotonation using s-BuLi or i-PrLi and chiral diamines in THF: the diamine matters

Author

Carbone, Giorgio, O'rien, Peter, and Hilmersson, Goran

Subjects
Amines -- Chemical properties, Nuclear magnetic resonance spectroscopy -- Usage, Organolithium compounds -- Structure, Organolithium compounds -- Chemical properties, Organolithium compounds -- Electric properties, Sparteine -- Chemical properties, Sparteine -- Electric properties, Tetrahydrofuran -- Structure, Tetrahydrofuran -- Chemical properties, Chemistry
Abstract

The NMR spectroscopic analysis has shown that it is possible to perform highly enantioselective asymmetric deprotonation reaction by using i-PrLi or s-BuLi/(+)-sparteine surrogate in THF. The studies have shown that these are the first examples of highly enantioselective asymmetric deprotonation reactions by using organolithium/diamine complexes in THF.

Published
2010

46. Asymmetric deprotonation of N-boc piperidine: react IR monitoring and mechanistic aspects

Author

Stead, Darren, Carbone, Giorgio, O'Brien, Peter, Campos, Kevin R., Coldham, Iain, and Sanderson, Adam

Subjects
Heterocyclic aromatic compounds -- Chemical properties, Heterocyclic aromatic compounds -- Electric properties, Organolithium compounds -- Chemical properties, Organolithium compounds -- Electric properties, Sparteine -- Chemical properties, Sparteine -- Structure, Chemistry
Abstract

Combination of s-BuLi and a (+)-sparteine surrogate is used to recognize the high yielding asymmetric deprotonation trapping of N-Boc piperidine. The lithiation by in situ react IR is used to facilitate the direct observation of a prelithiation complex.

Published
2010

47. [Definition of acute heart failure]

Author

Metra, Marco, Carbone, Giorgio, Lombardi, Carlo, Vescovo, Giorgio, BORGHI, CLAUDIO, Metra, Marco, Carbone, Giorgio, Lombardi, Carlo, Borghi, Claudio, and Vescovo, Giorgio

Subjects
sign, Heart failure, synptom, Acute
Abstract

Acute heart failure (AHF) is a potentially life-threatening condition that may arise as a deterioration of a previous heart failure or may be the first presentation of heart failure. Several causes or precipitating factors have been listed, as well as different mechanisms have been described, thus leading to a broad spectrum of clinical presentations. Symptoms and signs of AHF have a strong clinical and prognostic significance and are kept into consideration to guide disease management. In particular, a higher clinical severity or a worse prognosis are associated with lower blood pressure levels, fluid overload, evidence of myocardial ischemia or renal impairment. Putatively, interventions addressed to restore these factors may play a role in the management of AHF.

Published
2014

48. Definizione di scompenso cardiaco acuto

Author

Metra, Marco, Carbone, Giorgio, Lombardi, Carlo Mario, Borghi, Claudio, and Vescovo, Giorgio

Subjects
Cardio-renal syndrome, Dyspnea, Disease management, Cardiac edema, Critical pathways, Heart failure, Cardiology and Cardiovascular Medicine
Published
2014

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