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【目的】通过生物信息学方法，分析在肝衰竭中高表达的载脂蛋白H（APOH）在疾病发生发展中的功能与机制。【方法】从GEO数据库下载多个芯片数据集（GSE14688、GSE38941和GSE96851），以5筛选出差异表达基因，通过Cytoscape及R对前10位关键基因中的APOH基因进行GO生物学功能富集分析和KEGG信号通路分析，并进一步在慢乙肝相关肝衰竭组织中进行表达验证。【结果】共筛选出2438个差异表达基因，其中，1162个上调基因，1276个下调基因。蛋白质相互作用网络分析发现10个枢纽基因分别为：KNG1、IGF1、SPARC、APOH、CLU、SERPING1、TGFB2、CDC37L1、PCYOX1L和APOOL。通过慢乙肝相关肝衰竭组织验证发现APOH在肝衰竭组织中高表达，GeneMANIA预测APOH和炎症反应有关。GO分析及KEGG分析显示，APOH与补体/凝血级联通路以及碳代谢通路密切相关，并且，与补体C3（complement C3）的表达水平呈明显的正相关性。【结论】APOH在肝衰竭组织中高表达，可能通过补体C3调控补体/凝血级联通路以及碳代谢通路参与肝衰竭的发生发展。

Copyright of Chinese Journal of Rehabilitation Medicine is the property of China Association of Rehabilitation Medicine, China-Japan Friendship Hospital and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Fiber Inspection is the property of China Fiber Inspection and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Henan Agricultural Sciences is the property of Editorial Board of Journal of Henan Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Chongqing University of Technology (Natural Science) is the property of Chongqing University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agricultural Resources & Environment / Nongye Ziyuan yu Huanjing Xuebao is the property of Journal of Agricultural Resources & Environment Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Automobile Technology is the property of Automobile Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Biology Teaching is the property of East China Normal University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Ordnance Industry Automation is the property of Editorial Board for Ordnance Industry Automation and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To summarize the experience of diagnosis and treatment of Takotsubo syndrome (TTS) after liver transplantation. Methods Clinical data of one TTS patient after liver transplantation was retrospectively analyzed. Clinical features, diagnosis and treatment strategies were summarized, and literature review was conducted. Results A 43-year-old female patient successfully underwent split liver transplantation due to primary biliary cirrhosis for 8 years. At postoperative 3 d, the patient developed anxiety, irritation, dyspnea, disorientation, hypotension, N-terminal pro-brain natriuretic peptide (NT-proBNP) of >35 000 pg/mL, creatine kinase isoenzyme (CK-MB) of 5.9 U/L and troponin I (TnI) of 1.78 μg/L. Electrocardiogram indicated the signs of sinus rhythm. Echocardiography indicated diffuse weakening of the left ventricular wall motion and spherical dilatation of the apex, accompanied with moderate and severe regurgitation of the mitral valve and tricuspid valve. The left ventricular ejection fraction (LVEF) declined to 23%, whereas no abnormal segmental motion of ventricular wall or corresponding electrocardiogram changes were observed. The possibility of acute coronary syndrome was excluded. The InterTAK diagnostic score was 73. The diagnosis of TTS after liver transplantation was considered. Metoprolol, coenzyme Q10, recombinant human brain natriuretic peptide, deacetyl lanatoside and lorazepam were given. Echocardiography at postoperative 10 d showed that the left ventricular function was significantly improved and the LVEF recovered to 50%. The patient was discharged 40 d after liver transplantation. The liver function was recovered well. During postoperative follow-up, she was given with metoprolol till the submission date, and no recurrence was reported. Conclusions TTS after liver transplantation is rare in clinical practice. It is difficult to make the diagnosis. The condition of TTS is severe and clinical prognosis is poor. Prompt diagnosis and interventions should be implemented. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Agricultural Science & Technology (1008-0864) is the property of Journal of Agricultural Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Enhancing energy efficiency and improving ecological environment are global issues closely related to the theme of the times. It is of great significance to study the relationship between industrial agglomeration and energy eco-efficiency to promote the coordinated development of ecology and economy・ This study uses the data of different industries in China from 2001 to 2016 to measure the agglomeration level of various industries by the spatial Gini coefficient. Based on the super-efficiency SBM model, the energy eco-efficiency of each industry is measured. With the help of panel threshold regression model, this paper analyzes the nonlinear relationship between industrial agglomeration and energy eco-efficiency. The results show that： the overall development trend of China5 s industry was good from 2001 to 2016, the level of industrial agglomeration showed a fluctuating rise, the degree of industrial agglomeration was stable, and the proportion of medium and high concentration industries was high・ From 2001 to 2016, China's energy eco-efficiency showed an overall upward trend, but the differences of various industries were significant. Mostly technology intensive industries had high efficiency value, and mostly resource intensive industries had low efficiency. The industry cluster index showed double threshold characteristics to energy eco-efficiency, while science and technology level and environmental regulation showed single threshold characteristics to energy eco-efficiency. The scale of industries, the proportion of state-owned enterprises and foreign investment had different effects on energy eco-efficiency. Deepening the division of labor and cooperation among enterprises, liberating the productivity of state-owned enterprises and improving the environment for foreign investment will enhance the promotion of energy eco-efficiency. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Agricultural Science & Technology (1008-0864) is the property of Journal of Agricultural Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Transcranial direct current stimulation technology is a new type of brain stimulation technique that has been proved to improve muscle strength, aerobic endurance, and cognitive ability. However, whether transcranial direct current stimulation can improve the ability of lower limb power output or not is less researched. OBJECTIVE: To investigate the effect of single-session anodal transcranial direct current stimulation at bilateral brain motor areas on countermovement jump performance. METHODS: Twelve healthy male college students, (24.25±1.21) years old, height: (175.91±4.60) cm, weight: (76.56±8.72) kg, were recruited. Randomized crossover design was used, and the subjects were randomly assigned to anode stimulating group or sham stimulating group. The experiment was conducted twice, with an departing interval of 7 days. All the subjects were given 2 mA anodal or sham stimulation for 20 minutes targeting the bilateral motor cortex. A countermovement jump test was conducted before each stimulation. Jump height and relative maximum power were recorded immediately after stimulation and every 10-minute intervals during 1 hour after stimulation, in order to analyze the effect of anodal stimulation on the countermovement jump of healthy men. Pearson’s correlation analysis was used to judge the test-retest reliability of the experiment, and repeated measurement variance analysis was used to compare the jump height and relative maximum power of the countermovement jump test between the two groups at different time periods. The implementation of the study complied with the relevant ethical requirements of Wuhan Sports University with an approval No. 2019006. All the subjects voluntarily participated in the trial and signed an informed consent form. RESULTS AND CONCLUSION: For the test-retest reliability, the correlation coefficient of jump height was 0.921 (P < 0.001), and the correlation coefficient of relative maximum power was 0.938 (P < 0.001). For the relative maximum power, the main effect of the group was significant(P < 0.05, pη²=0.557). The relative maximum power of the stimulating group (4.9%) was significantly higher than that of the sham stimulating group. There were no significant differences in the interaction of group × time and the main effect of the time on the relative maximum power (P > 0.05, pη²=0.072 and 0.062). For the jump height, the interaction of group × time and the main effect of group and time had no significant difference (P > 0.05, pη²=0.088, 0.196 and 0.069). These findings indicate that the maximum output power of lower extremities of healthy adult males is increased within 1 hour after anodal transcranial direct current stimulation (2 mA, 20 minutes) at bilateral motor areas of the brain. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Changzhou University (Social Science Edition) is the property of Editorial Department of Journal of Changzhou University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to improve the long-term prediction accuracy of PM2. 5, this paper proposed a TSMN (time series memory network) prediction model based on deep learning by taking air pollutants and meteorological factors as the influencing factors. The model consisted of two components. The local memory component used external memory to improve the long-range memory capacity of the model, and cooperated with the neighborhood component that modeled the multi-site spatial relationship to complete long-term prediction of PM2. 5 from the perspective of time and space. This paper compared the TSMN model with multiple models by using different evaluation indicators. Comparing the TSMN model with the better-performing CNN-1.STM model, the RMSE and MAE of this model goes down 5. 2% and 5. 7% respectively,and the R2 goes up 7. 5% . The experimental results show that the TSMN model can effectively improve the long-term prediction accuracy of PM2. 5 concentration. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Henan Agricultural Sciences is the property of Editorial Board of Journal of Henan Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Ecology & Rural Environment is the property of Journal of Ecology & Rural Environment Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The pollution production coefficient of sheep-breeding is lacking in recent years, since most previous studies focused mainly on pigs, cattle, and chickens in the livestock and poultry breeding industries. This study aims to systematically explore the producing characteristics of pollutants from large-scale sheep farms in Northern China, and thereby to construct the pollution production coefficient for the sheep breeding industry. Three typical sheep farms were selected for sentinel monitoring experiments in Northeast, North and Northwest China. The sheep were divided into four groups according to the feeding stages, including the nursling, fattening, mature, and barren stages. In each group, five normal, healthy and similar weight sheep were randomly selected using the age and gender of different sheep breeds. A metabolic cage was adopted in the experiment, where feed and water were supplied regularly and quantitatively. The trial period was from July to September 2019. The monitoring items included the daily feed intake, water intake, as well as the amount of feces and urine of each sheep. The feed of each group, the feces and urine samples of each sheep were collected for 3 consecutive days to determine physical and chemical indicators for the pollution production coefficients. The results showed that there was great difference in the regularity of pollutant generation for the breed, age, and gender in a sheep farm. The daily feed and water intake of Liaoning cashmere goat in northeast China, the crossbred F1 of Dorper and Hu sheep in north China, and the Tan sheep in northwest China were 1.45, 1.29, and 2.24 kg, while, 1.82、2.73, and 0.72 L, respectively. The daily production of feces and urine for the Liaoning cashmere goat, the crossbred F1 sheep, and Tan sheep were 0.69, 0.61, and 0.94 kg, 0.77, 1.19, and 0.42 L, respectively. The daily fresh weight of feces and fresh weight of feed, dry weight of feces and dry weight of feed, urine volume and water consumption all showed significant positive correlation (0.8

Copyright of Journal of Ecology & Rural Environment is the property of Journal of Ecology & Rural Environment Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A dramatic increase in the amount of chicken manure is posing a great challenge on the social community, ecological environment, and human health, as the growing demand of chicken meat and eggs in China. Fortunately, composting process is an effective, sustainable, economic and natural way to recycle the decomposed organic materials, with an emphasis on the manure treatment prior to land application. Nevertheless, there are usually lots of odor emissions during the composting of nitrogen-rich chicken manure. The C/N ratio of raw materials markedly determines the compost maturity and the odor emissions during composting. At present, lots of previous studies focused on the effect of C/N ratio on the compost maturity and quality. However, only a few reports paid attention to the odor (NH3 or H2S) emissions during chicken manure composting. In this study, three C/N ratios, including 14, 18 and 22, were selected from the co-composted chicken manure and cornstalks as the bulking agent, to improve the compost quality, while decrease the odor emissions. An attempt was made to explore the comprehensive effect of C/N ratio on maturity and odor emissions (NH3 and H2S) during chicken manure composting. The aeration was in an intermittent mode (Sated 30 min, stopped 30 min), and the rate was 0.2 m³/h. The composting lasted 35 days, where the sampled on the day of 0, 3, 7, 14, 21, 28, 35, respectively. The basic physicochemical and maturity indexes were measured, including temperature (T), oxygen (O2), inorganic nitrogen content (NH+4-N, NO-3-N), pH value (pH), Electrical Conductivity (EC), C/N ratio, Germination Index (GI), and the element content (C, N and S). Odor emissions (NH3 and H2S) were continuously monitored daily. A canonical correspondence analysis (CCA) was also used to analyze the microbial community composition, as well as their correlation with physicochemical indexes and odor emissions. The results showed that the final compost with the C/N ratio of 14 was not mature, while both the treatment with the C/N ratios of 18 and 22 reached the maturity standard. In terms of odor emissions, the C/N ratio of 18 treatment had the highest NH3 emission, because of the higher degradation of organic matter. When the C/N ratio ranged from 18 to 22, the NH3 emission and total nitrogen (TN) loss decreased with the C/N ratio increased. In addition, the cumulative H2S emission and the total sulfur (TS) loss were the highest in the C/N ratio of 14 treatment, while those in the C/N ratio of 18 and 22 treatments greatly decreased, indicating no significant difference. Moreover, the C/N ratio of 18 treatment had the highest microbial diversity, compared with other two treatments during the whole composting period. Furthermore, the microbial community compositions in the C/N ratios of 14 and 18 treatments (Firmicutes) were significantly different from those in the C/N ratio of 22 treatment (Actinobacteria and Firmicutes). More importantly, the CCA showed high temperature, high pH, and hypoxic environment can be beneficial to the proliferation of Firmicutes, and thereby to promote the emission of H2S and NH3. In an opposite case, high abundance of Actinobacteria can decrease the H2S and NH3 emission. As such, the recommended C/N ratio was 18~22 during co-composting of chicken manure and cornstalk. Specifically, the appropriate ratio can also be determined according to the number of cornstalks. [ABSTRACT FROM AUTHOR]

With the development of intensive and large-size livestock farming, a large amount of livestock manure has brought environmental pollution in some areas. Aerobic composting is a widely-used and efficient technology for the treatment and utilization of organic waste, which realizes harmless treatment, quantity reduction, stabilization and reutilization. However, there are several issues such as low maturity degree of compost product and emission of polluting gases during the process of composting, moisture content (MC) is one of the most important factors of composting. In order to study the effects of initial MC on maturity and pollution gas emissions during the sheep manure composting and optimize the process conditions, an experiment was carried out in 60 L sealed fermenters for 35 days. In this research, sheep manure and cornstalk were used as raw composting materials. According to the different initial MC, high-humidity sheep manure without any cornstalk was set as MC75 treatment, cornstalks were thoroughly mixed with sheep manure in certain proportions to adjust the initial MC to be 70%, 65%, 60% and 55%, respectively. C/N ratio of the composting mixture of five treatments was adjusted to 22 approximately by adding urea. The chemical and physical characters and maturity indicators such as temperature, germination index, electric conductivity, and pH value were analyzed, and continuous monitoring of pollution gases (CH4, N2O, and NH3) were conducted. The results demonstrated that the sheep manure composting pile with the MC of 75% could not be activated successfully, the compost product still had the risk in farmland utilization because it did not experience the thermophilic period (>50 ℃). However, lots of greenhouse gases such as CH4 and N2O were released and the greenhouse gas emissions equivalent was the largest among all treatments during the experiment (41.4 g/kg). While the co-composting process could be started effectively for all treatments with sheep dung and cornstalks. MC70%, 65%, 60% and 55% treatments all entered into thermophilic stage and reached the peak values of temperature on the 2nd and 4th day, respectively. The thermophilic phase lasted for 8-10 d to reach the compost sanitary requirements. Moreover, the germination index of all treatments under the addition of cornstalks were higher than 80%, the electric conductivities were below 4 mS/cm and the pH values were in the range of 8 to 9 at the end of composting, which could be biologically non-toxic and meet the maturity standard completely. The treatment with the initial MC of 65% had long thermophilic phase (10 d) and high biodegradation degree, whose degradation rate of dry material reached 45%. Meanwhile, compared to the other treatments, the total nitrogen loss and the total greenhouse effects were decreased by 4.81%-16.99% and 7.56%-48.62%, respectively. Consequently, sheep manure with high moisture content should be collected and disposed frequently in sheep farming, and it is not environmentally friendly to pile up without any bulking agent. The optimal initial moisture content is about 65% in this study during the aerobic co-composting of sheep manure and cornstalk. In addition, the control of ammonia emissions by adding additives could be taken into account in future research. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)