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Objective: To explore the changing trajectory of psychological distress in young and middle-aged patients during peridialysis period. Methods: Totally 122 patients in the peridialysis period were investigated with the Self-Designed General Data Questionnaire, Distress Screening Scale（DSS）,Connor-Davidson Resilience Scale（CD-RISC）,Social Support Revalued Scale（SSRS） and Self-Perceived Burden Scale（SPBS） at the time of diagnosis, initial dialysis, and dialysis for 1 month,2 months and 3 months, respectively. The growth mix model was used to identify trajectory categories. Results: The time main effect of scores of DSS, CD-RISC and SPBS in peridialysis patients was statistically significant（Ps ＜0.05）,the scores of DSS and SPBS were the highest at the initial dialysis and the lowest at 3 months of dialysis. The CD-RISC scores were the lowest at the first dialysis and the highest at 3 months of dialysis. The trajectory of psychological distress was divided into 3 types, namely continuous high level（26.20%）,high level decline（40.72%）,and medium-low level decline（33.08%）.Conclusion: The psychological distress of young and middle-aged peridialysis patients shows different trajectories from diagnosis to regular dialysis. Clinical staff should pay more attention to the psychological status of the first-time dialysis patients. [ABSTRACT FROM AUTHOR]

Objective To analyze the clinical characteristics of vasovagal syncope patients and to discuss if they exhibit factors affecting the existence of presyncope. Methods Patients with vasovagal syncope admitted to Beijing Tiantan Hospital, Capital Medical University from January 2017 to June 2022 were included retrospectively. Their general data, results of head-up tilt test and hemodynamic indexes were collected. Multivariate logistic regression analysis was used to explore the influencing factors of presyncope. Results A total of 1211 patients with vasovagal syncope were included in the study. The patients were divided into two groups according to the presence or absence of presyncope, with 582 (48.06%) cases in the non-presyncope group and 629 (51.94%) cases in the presyncope group. There were statistically significant differences in the following factors between the two groups: age (t=6.006, P<0.001), number of female (χ2=11.749, P=0.001), BMI (t=2.562, P=0.011), and history of hypertension (χ2=12.643, P<0.001), diabetes (χ2=9.129, P=0.003) and cerebral vascular disease (χ2=4.060, P=0.044). There was no significant difference in the results of head-up tilt test between the two groups (χ2=6.205, P=0.102). Multivariate logistic regression analysis showed that age≤60 years (OR=1.727, 95%CI 1.347-2.214, P<0.001) and being a female (OR=1.440, 95%CI 1.122-1.847, P=0.004) were the risk factors of presyncope. Conclusions Vasovagal syncope patients with≤60 years of age and female are more likely to have presyncope before syncope. This may be related to the function of autonomic nervous regulation . [ABSTRACT FROM AUTHOR]

In response to the demand of approaching justice movement and scientific and technological progress, the smart court, as a product of judicial intelligence, applies emerging scientific and technological means to the trial and management of the court. The construction of the intelligent court should not only pay attention to the improvement of litigation efficiency in the system design, but also pay attention to the protection of the litigation rights of the parties. As the basic concept of jurisprudence, "right" should be the logical starting point of the legitimacy of smart courts. The construction of smart courts should be promoted with rights relief as the logical basis and procedural choice as the logical focus. The construction of intelligent court should take rights as the starting point for top-level design, provide parties with a variety of procedural options to realize the protection of litigation rights, and focus on "procedural options" to provide institutional guarantee. [ABSTRACT FROM AUTHOR]

The development of government social media is faced with many opportunities and challenges, such as the technological change of intelligent media, the development of whole-process people’s democracy and the achievement of good governance of digital government. This study analyzes the dimensions of development of government social media in the era of intelligent communication from four aspects: technology, user, platform and ecology. In terms of technology dimension, we attach importance to citizens as users, develop intelligent production and accurate distribution with user orientation. In terms of user dimension, we attach importance to users as citizens, strengthen communication between government and the public and promote orderly political participation. In platform dimension, we attach importance to politics as a product, develop products with characteristics of “cloud” interconnected, transparent and simulated, establish a governance model based on collaboration, participation and common interests. In ecology dimension, we attach importance to politics as a product, the development of government social media must commit to a people-centered philosophy. The essence of the four development dimensions is to promote the coupling of intelligent technology and social governance through intelligent government social media, modernize China’s system and capacity for governance, and transform the institutional advantages of whole-process people’s democracy into governance efficiency. [ABSTRACT FROM AUTHOR]

Objective To investigate the hemodynamic parameter characteristics of patients with neurogenic orthostatic hypotension (nOH) in the head-up tilt test (HUTT). Methods Patients diagnosed with typical nOH in the syncope clinic of our hospital were selected. Hemodynamic parameters of these patients during HUTT including systolic blood pressure, diastolic blood pressure, mean arterial pressure, heart rate, stroke volume, cardiac output and systemic vascular resistance in the supine and tilted upright positions were collected, and retrospectively analyzed. The patients were divided into two groups according to age (age≥60 years group with 46 patients and age < 60 years group with 36 patients ). The characteristics of the above hemodynamic parameters were compared between the two groups in the supine position, and at the 1st, 2nd, and 3rd minute in tilted upright position. Results For all patients, systemic vascular resistance does not increase from the supine to the tilted upright position. The increase of heart rate, the decrease of stroke volume and their degree of variability from the supine to the titled upright position are significantly lower in patients≥60 years than those in patients < 60 years. Conclusion In patients with typical nOH, the increase of systemic vascular resistance from the supine position to the tilted upright position is impaired. Among these patients < 60 years, heart rate increases and stroke volume decreases significantly in the tilted upright position. [ABSTRACT FROM AUTHOR]

Objective To investigate the diagnostic value of transcranial Doppler (TCD) combined with headup tilt test (HUTT) in patients with orthostatic cerebral hypoperfusion syndrome (OCHOs). Methods We selected the patients going to hospital due to syncope or suspected orthostatic intolerance, and their etiology was considered as OCHOs. Cerebral blood flow parameters and hemodynamic parameters of patients were collected separately by TCD and HUTT, and healthy control group was set up. TCD cerebral blood flow parameters and HUTT hemodynamic parameters were compared between the OCHOs patients and the control group. Results A total of 56 OCHOs patients (case group) and 21 healthy adults in the control group are enrolled. In terms of TCD cerebral blood flow parameters, compared with the supine position, the absolute values of the decrease of systolic, enddiastolic and mean cerebral blood flow velocity in the case group are significantly higher than those in the control group during the tilt upright position; the absolute values of the increase of pulse index and circulation resistance index are also significantly higher than those in the control group (P < 0. 01). There is no significant difference in HUTT hemodynamic parameters between the two groups (P > 0. 05). The receiver operator characteristic curve is drawn. Compared with the supine position, systolic, end-diastolic and mean cerebral blood flow velocity in the case group decrease by 14. 5, 9. 5 and 13. 5 cm / s, respectively during the tilt upright position. Their sensitivity is separately 94. 6%, 87. 5% and 91. 1% while the specificity is separately 95. 2%, 85. 7% and 95. 2% in diagnosing OCHOs (P < 0. 01). Conclusion TCD combined with HUTT plays an important role in diagnosing OCHOs. [ABSTRACT FROM AUTHOR]

Objective To evaluate the clinical efficacy of heterozygous living donor liver transplantation for pediatric maple syrup urine disease. Methods A 3-year-old boy was admitted to the hospital on July 5, 2017 due to maple syrup urine disease for half a year. The child presented with paroxysmal dysarthria and motor dysfunction of the lower limbs under fasting status for half a year, accompanied with obvious maple syrup urine odor and slow language development. No other growth abnormality or mental defects were observed. Serum branched chain amino acid (BCAA) assay detected that the level of leucine was 684 μmol/L and 559 μmol/L for the valine. The child was diagnosed with maple syrup urine disease type b based on gene detection combined with BCAA assay. Living donor liver transplantation from his biological father was performed. Postoperatively, routine immunosuppression, anti-virus, anti-infection therapies, maintenance of fluid, electrolyte, and acid-base balance and other necessary nutritional support were given. The dose of tacrolimus was adjusted according to biochemical parameters and cytochrome P450(CYP)3A5 genotype of the recipient. Glucocorticoid administration was terminated at approximately 6 months after operation. Results The liver function of the recipient was recovered to normal range at postoperative 1 month, and basically stabilized at 3 years after surgery. The amino acid level was decreased to normal level immediately after operation, and BCAA was continually declined after normal diet for postoperative 1 month. As of the submission date, the recipient grew well in a stable condition and achieved high quality of life. Conclusions Heterozygous living donor liver transplantation is a safe and effective treatment of maple syrup urine disease, which reduces the possibility of sudden acute metabolic events, significantly improves the quality of life of the recipient and provides a novel idea for surgical treatment of maple syrup urine disease. [ABSTRACT FROM AUTHOR]

Objective·To analyze the condition of ocular surface and tear film after reconstruction of palpebral margin with lip mucosa graft. Methods· Fifteen patients with palpebral margin defect who were treated in the Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine from November 2017 to December 2019 were selected. All patients underwent the lip mucosa graft for palpebral margin reconstruction. A series of ocular surface examination, some ophthalmological physical examination and a questionnaire were prepared for each patient 6‒8 weeks after surgery. The ocular surface examination was constituted of tear meniscus height (TMH), tear break-up time (BUT) and Schirmer test. The ophthalmological physical examination included affected palpebral fissure height (PFH) and levator function (LF). Finally, Ocular Surface Disease Index (OSDI) was used as a questionnaire. Results·There was no significant difference in TMH between fellow eyes and operated eyes [(0.24± 0.07) mm vs (0.23±0.11) mm, P=0.316]. There was no significant difference in BUT between fellow eyes and operated eyes [(10.75±2.31) s vs (7.75± 2.05) s, P=0.065]. There was no significant difference in the result of Schirmer text between fellow eyes and operated eyes [(10.20±1.96) mm/5 min vs (9.33±2.04) mm/5 min, P=0.376]. There was no significant difference in PFH between fellow eyes and operated eyes [(10.16±1.18) mm vs (10.11±2.11) mm, P=0.761]. There was no significant difference in LF between fellow eyes and operated eyes [(9.59±0.93) mm vs (9.03±1.02) mm, P=0.552]. The score of OSDI was 26.44±3.88 in average. Conclusion·The lip mucosa graft for treating palpebral margin defects gives a satisfactory result in tear film stability and binocular symmetry. Patients may have dry eyes according to the score of OSDI 6‒8 weeks after surgery. [ABSTRACT FROM AUTHOR]

Objective: To explore the expression of recombinant human sequence similarity family 189 member B (FAM189B, alias COTE1) in hepatocellular carcinoma tissues and its correlation with the prognosis of hepatocellular carcinoma patients. Methods: Collect 59 patients undergoing radical resection of hepatocellular carcinoma, take their hepatocellular carcinoma tissues and adjacent tissues, use immunohistochemistry to detect COTE1 expression, analyze the relationship between COTE1 expression and clinicopathological parameters, and use Kaplan-Meier survival curve The relationship between COTE1 expression and patient prognosis was analyzed, and the COX proportional hazard regression model was used to analyze the prognostic factors. Results: The results of immunohistochemistry showed that 37 cases of COTE1 were highly expressed in hepatocellular carcinoma tissues, and COTE1 was highly expressed in 24 cases of adjacent tissues. The expression rate of COTE1 in hepatocellular carcinoma tissues was significantly higher than that in adjacent tissues (P< 0.05); COTE1 expression is correlated with alpha-fetoprotein (AFP) value and tumor recurrence (P<0.05), but has nothing to do with age, gender, and tumor size (P>0.05). Kaplan-Meier curve analysis found that patients with hepatocellular carcinoma with high COTE1 expression had a shorter postoperative survival period (P<0.05). COX proportional hazard regression analysis found that COTE1 expression can be an independent risk factor affecting the prognosis of patients with hepatocellular carcinoma (P<0.05). Conclusion: The expression of COTE1 in hepatocellular carcinoma tissues is higher than that in adjacent tissues. COTE1 expression can be used as an independent factor to predict the prognosis of patients with hepatocellular carcinoma. [ABSTRACT FROM AUTHOR]

随着对肝脏疾病的深入研究,越来越多的证据表明肝纤维化是一种可逆的病理生理过程。肝活检组织学评价是评价肝纤维化的金标准,除此外还有血清学评价方法,虽然这些方法都可以用于肝纤维化的评价,但或多或少都存在一些缺陷。随着影像学技术的发展,出现了一系列可用于评价肝纤维化的影像技术。本文主要对这些影像学方法的优缺点进行综述。 [ABSTRACT FROM AUTHOR]

Objective: To investigate the efficiency of Quick Cognitive Screening Scale for Elderly ( QCSS-E) in screening mild cognitive impairment (MCI) and mild-moderate dementia with Alzheimer Disease ( AD) from the elderly in community. Methods: A total of 1298 elderly aged 55 years or more were recruited from a community and divided into normal control (NC) group (n = 629), MCI group (n =573) and mild-moderate AD group (n -96) according to the Peterson MCI diagnostic criteria and DSM-5 neuroeognitive impairment AD diagnostic criteria as the gold standard. According to the gold standard, the positive predictive value and negative predictive value of MCI and AD were calculated. ROC curve was used to analyze the differentiation of the total score of the scale. Results: The positive predictive value of MCI and the negative predictive value were 67.6% and 83.9% respectively. The positive predictive value of AD screening was 64. 2% and the negative predictive value was 96. 9%. ROC curve analysis found that the AUC of QCSS-E total score screening for normal and MCI, normal and mild-moderate AD, MCI and mild-moderate AD were 83. 5%, 98. 0% and 85. 6% , respectively. Conclusion: The QCSS-E total score and each dimension score perform well in early AD screening, among which visual space, verbal fluency, abstract ability and delayed memory are the sensitive indicators for early AD recognition. [ABSTRACT FROM AUTHOR]

In 2015, the World Health Organization's classification of lung cancer proposed the concept of spread through air spaces (STAS) as a new model for lung adenocarcinoma invasion. STAS refers to the spread of lung cancer cells through the airways in the lung parenchyma beyond the edge of the main tumor. In recent years, with the deepening of STAS research, the results show that STAS as an invasive method is related to other invasive behaviors and metastasis. STAS is closely related to the prognosis of lung cancer and is also independently associated with the risk of recurrence. Notably, the prognosis of STAS-positive patients varies greatly with the choice of surgical methods. In imaging, STAS has its own special imaging features that can be used as a tool for estimating STAS likelihood. Therefore, whether it is possible to determine the presence or absence of STAS by imaging and other methods could become a significant guidance for selecting surgical methods and improving patients' prognosis. This review will focus on the recent research on the association of STAS with imaging, gene mutations, and different types of lung cancer. [ABSTRACT FROM AUTHOR]

Reinforced concrete slab-column structure is a common architectural form with excellent economic and technical indicators. However, slab-column structure without shear reinforcements has low lateral stiffness and poor seismic performance compared with reinforced concrete frame, due to the force-transferring mechanism and punching shear of the slab-column connection. In the past decades, many research achievements about the seismic performance of slab-column structure have been made, but the research is still insufficient. The state-of-the-art on the seismic performance of slab-column structure and design method in terms of seismic experiment, nonlinear analysis of equivalent frame model and seismic evaluation is introduced in the paper. Meanwhile, the summary, generalization and comment for the achievement and design method is made to provide ideas for subsequent research. In subsequent research, mechanism of connection punching shear should be revealed. The punching shear criteria or formula should be obtained based on the mechanism and can be used in nonlinear analysis model. Seismic design procedures should be set up based on the data from the structural nonlinear analysis. [ABSTRACT FROM AUTHOR]

In order to realize the effective control of various units in the microgrid such as renewable energy power generations and power storage, a universal control experimental platform for microgrid is constructed based on DSP module. The hardware components of the platform include mainly the DSP system controller, touch screen, the host compute, and the software components include the module control program, the underlying driver and communication program. Based on powerful capabilities of DSP, such as data acquisition and computing, the experimental platform achieves the objective of effective control of power generated by kinds of renewable energies in microgrid, and provides a practical platform to improve the experimental ability of electrical students in colleges and universities, and brings experimental support for scientific research in the field of electrical engineering. [ABSTRACT FROM AUTHOR]

Blueberry has a very rich source of bioactive compounds, including vitamin C and E, and phenolic compounds (anthocyanins). Many studies indicated that anthocyanins are beneficial to human health by reducing the risk of cardiovascular disease and improving vision. However, anthocyanins have a poor stability. Microencapsulation is an effective and promising method to prevent the degradation of functional ingredients. In order to explore the effect of storage time and temperature on the quality of blueberry anthocyanin microcapsules, and find out the appropriate storage conditions, quality evolution of microcapsules stored for 6 months under -18, 4 and 25 ℃ was investigated respectively. The results revealed that there were no significant differences in water activity, hygroscopicity and encapsulation efficiency of encapsulated powders during the storage (P>0.05), which meant that anthocyanins were coated successfully in microcapsules using protein-polysaccharide as wall material. However, with the increase of storage time, the caking degree showed a gradual increasing trend (P<0.05), although the differences under different temperatures were insignificant (P>0.05). It was also found that the glass transition temperature decreased during the storage. One of the most remarkable things was that there was a sharp decrease in the glass transition temperature of anthocyanins stored for more than 4 months. During the storage, the total anthocyanins and total phenolics of microcapsules showed a decreasing trend (P<0.05), while the latter declined less. Storage under -18 ℃ could increase the stability of anthocyanins and total phenolics obviously (P<0.05). It needed to be emphasized that the presence of whey proteins may improve the stability of malvidin-3-glucoside. Scanning electron microscopic images of encapsulated powders showed that particle size increased gradually due to the glass transition temperature declining. This led to antioxidant capacities, measured by ABTS radical scavenging assay and ferric iron reducing antioxidant power, decreased significantly (P<0.05). The peak intensity at 1 637, 1 508 and 1 030 cm-1 was weakened, which was associated with the possible weakening of the interactions between core and wall materials as well as the interactions among wall materials. Moreover, with the extension of storage time, encapsulation productivity of encapsulated powder and its release rate in water decreased gradually (P<0.05), and the encapsulated powder stored under -18 ℃ had a higher encapsulation productivity and release rate in water than others (P<0.05). It could be due to that low temperature inhibited the weakening of intermolecular force. In addition, there existed an interaction effect of storage time and temperature on glass transition temperature, encapsulation productivity, release rate in water, value of ABTS and content of monomeric anthocyanins including malvidin-3-glucoside, peonidin-3-glucoside together with cyaniding-3-O-glucoside. Compared with the storage time, storage temperature was a less important factor affecting the stability of blueberry anthocyanin microcapsules. In general, whey protein isolate, maltodextrin, β-cyclodextrin and gum arabic are combined as wall materials, for encapsulation can benefit blueberry anthocyanins through alleviating their quality decrease during the storage. Moreover, the weakened interaction force between the molecules possibly causes a decline in the quality of blueberry anthocyanins during the storage. The suitable storage time and temperature are 3 months and -18 ℃, respectively. This research provides the theoretical basis for the application of blueberry anthocyanin encapsulates. [ABSTRACT FROM AUTHOR]

In order to implement efficient utilization of intermittent and variable wind energy，a new wind power hydrogen coupled with fuel cell microgrid experimental system is designed. Specifically，by using PLC the design and optimization of multiple controllers for rectifier，temperature，pressure and level in electrolytic hydrogen production system are completed. Also the pressure and temperature information of hydrogen storage bottles，compressing process control and hydrogen supplying process control are provided based on PLC. And the DC/AC inverter power control is implemented to control the output power of the fuel cell system. Furthermore，the coordinated control of the microgrid system is proposed to implement three different operating modes，including the independent operation of both wind power hydrogen subsystem and fuel cell power generation subsystem，as well as the system-wide operation of whole microgrid. Practical application shows that the microgrid system can not only achieve stable and secure operation of the subsystems，but also enable the switch of the corresponding operation mode depending on the system operating conditions. [ABSTRACT FROM AUTHOR]

Objective To study the conservative treatment for cesarean scar pregnancy (CSP) with proper medications. Methods One case of CSP with uterine apoplexy was reported. Medication regimens were illustrated as the conservative treatments for the patient with β-HCG>20 000 IU/L, in whom surgery was contraindicated. Results After two times of uterine artery embolization and chemotherapy (MTX50 mg), followed by three times of MTX50 mg cervical injection combined with oral mifepristone, serum β-HCG dropped to normal level and no adverse reactions were observed. Conclusion Clinical pharmacists could strengthen the safety and effectiveness of rational drug use by participating in the integrated pharmacy care. [ABSTRACT FROM AUTHOR]

How to use hyper-edge to model the multiple association relationship in network data and realize the prediction of potential hyper-edge link relationship has important practical significance. Existing Link prediction methods mainly focus on networks with pairwise relationships. However, directly applying existing link prediction methods to hyper-edge link prediction in hypergraph networks has certain limitations. Therefore, this paper proposed a hyper-edge link prediction model HVGAE（Heterogeneous Variational Hypergraph Autoencoder） based on heterogeneous variational hypergraph autoencoder. Firstly this method used hypergraph convolution to realize variational hypergraph autoencoder, and converted the hypergraph network data into a low-dimension representation. Then it added nodes near-neighbor similarity function to retain the structural information to the largest degree, so as to construct heterogeneous hyper-edge link prediction model. Experiments on three different types of hypergraph networks, the results show that HVGAE model have gained better prediction result compared with that of other baseline methods, indicating that the proposed model can better solve the problem of hyper-edge link prediction in the hypergraph network. [ABSTRACT FROM AUTHOR]

Streptomyces sp. YJ-81 with a herbicidal activity was isolated from the rhizosphere soil of Woodsia ilvensis collected from Erlong Mountain, Harbin. To uncover the active component and its herbicidal activity, the active compound from YJ-81 fermentation broth was isolated and purified by silica gel column chromatography, gel-filtration column chromatography, and semi-preparative high-performance liquid chromatography using herbicidal bioassay-guided fractionation. The active compound 1 was identified as herbimycin A by NMR spectroscopy. The seed germination assays on weeds and crops were performed and the result showed that herbimycin A at 100 mg/L could completely inhibit the seed germination of Setaria viridis and Amaranthus retroflexus, and have a certain inhibitory effect on the seed germination of other weeds (Echinochloa crusgalli, Portulaca oleracea, Chenopodium album) and crops (Oryza sativa, Lycopersicon esculentum, Citrullus lanatus, and Zea mays). The pot experiments showed that herbimycin A significantly inhibited the growth of A. retroflexus, P. oleracea, and C. album, and slightly inhibited the growth of S. viridis, E. crusgalli, and L. esculentum, but did not affect the growth of Z. mays, C. lanatus, and O. sativa. Especially, herbimycin A demonstrated crop safety to Z. mays, because no obvious phytotoxic symptom was observed on the leaves of maize, and no significant difference in the fresh weight of the aerial part and chlorophyll content of maize between the control and drug treatment even with 1000 mg/L of herbimycin A. Therefore, herbimycin A could be exploited as a safe, selective, and post-emergence herbicide in the field of maize. [ABSTRACT FROM AUTHOR]

As the quantity of space debris orbiting Earth to increases, the space harpoon has emerged as a promising solution for the removal of large space debris. By examining the characteristic properties of typically abandoned spacecraft, researchers have identified the final stage of a launch vehicle as an appropriate demonstration target for capture. To achieve this, a space harpoon with an integrated multi-level barbed structure was proposed and finite element dynamic simulations were conducted to study the anchoring effect of the space harpoon at different speeds. Subsequently, to simulate real-life conditions, the targets varying spin speeds were subjected and the harpoon's ability to anchor a moving target plate were analyzed. The results indicate that the optimal initial velocity for the space harpoon to effectively anchor the target plate is 70 m/ s, and moving targets can still be captured at this speed. Consequently, it can be conclude that using space harpoons to capture abandoned launch vehicles in orbit is feasible, and that the space harpoon capture method demonstrates low sensitivity to moving targets. [ABSTRACT FROM AUTHOR]

Objective: To investigate the relationship between coronary artery stenosis and P wave terminal potential in lead V1 in patients with CHD. Methods: 221 patients with coronary heart disease who hospitalized in the Department of Cardiology of our hospital in 2022. The PtfV1 of each case was calculated, and a total of 64 cases were included in the subgroup in which PtfV1 (+)(PtfV1≤ -0.04 mm·ms); a total of 157 cases were included in the subgroup in which PtfV1 (-) (PtfV1＞-0.04 mm·ms). The gender, age, coronary artery stenosis, smoking, diabetes, cholesterol, and low density lipoprotein (LDL) of each case were recorded. The basic clinical information of patients was analyzed by single factor Logistic regression analysis to explore the risk factors of PtfV1 (+), and then the meaningful variables were analyzed by multivariate Logistic regression analysis. Results: Single factor Logistic regression analysis showed that the risk factors of PtfV1 (+) included severe coronary artery stenosis, smoking, and age (all P<0.05). Multivariate Logistic regression analysis showed that severe coronary artery stenosis, smoking and age were independent risk factors of PtfV1(+) (all P<0.05). Conclusion: There was a correlation between coronary artery stenosis and P wave terminal potential in V1 lead. [ABSTRACT FROM AUTHOR]

In this paper,the problem of frequency support capability for doubly fed induction generators (DFIGs) in the future grid with high penetration of wind power is discussed, and a frequency stability controller based on maximum power tracking control and differential control is proposed. The relationship between grid frequency and frequency support capability of DFIGs is built, then the influence of the designed controllers on system frequency stability is analyzed. And the power system simulation software DIgSILENT/PowerFactory is used to set up the system simulation experiment platform, the result proves that the proposed frequency stability controller can effectively improve the frequency performance of the whole system. [ABSTRACT FROM AUTHOR]

According to characteristics of the experimental course teaching practice of signal analysis and processing, based on the open-source GNU Radio software architecture, an open, innovative exploratory experiment teaching platform is designed. By using the high efficiency C + + language to implement various signal processing module (block), the basic theory in the course, including filters, FFT transform, modulator/demodulator, channel codec module, can be easily implemented. By using the scripting language Python to construct flow graph, the signal processing blocks can be easily connected into a complete signal processing system; also, based on the practice of scientific research projects of teachers, a variety of application-oriented exploratory experiments can be carried out. By exploring the experiments in the form of organizing open research group, and reforming experimental course assessment methods and evaluation mechanisms, the comprehensive improvement of forms and effects of experimental teaching can be achieved and it will help to culture comprehensive and innovative professionals in the fields of electric engineering and information science. [ABSTRACT FROM AUTHOR]

A KingView based wind-hydrogen-fuel cell microgrid monitoring system is designed to implement the coordinated control of the wind turbine generation system, electrolytic hydrogen production system, compressed hydrogen storage system and fuel cell generation system. The hardware and software components of the system are introduced, and the technical route and the development process are described in detail. The development and application of microgrid monitoring system will not only implement three different operating modes including the wind power hydrogen production and storage operation mode, the fuel cell power generation operating mode as well as microgrid system-wide operation mode, ensuring a safe and stable operation of the microgrid system, but also help to provide a platform for the students of electrical engineering to carry out exploratory experiments in the cutting-edge technology in distributed generations and microgrid, and provide a strong experimental support conditions for teaching and research staffs to promote teaching reform and scientific research in the field of smart grid and microgrid. [ABSTRACT FROM AUTHOR]

Nowadays in the field of orthopedics, peripheral nerve injury has been affecting patients. Muscle atrophy and apoptosis in skeletal muscle atrophy, neuro muscular junction trophic factor of metabolic disorder occurs, reduction of muscle satellite cells, growth factors and mitochondria and a variety of enzyme changes are mechanism of denervated skeletal muscle atrophy. Electrical stimulation method and protect neurons and growth factor, nerve implantation to improve the rate of nerve regeneration and passive activities can be effective in the treatment of patients with. Research progress of of denervated skeletal muscle atrophy also tends to improve. [ABSTRACT FROM AUTHOR]

Objective To investigate the reasonable treatment effect of perioperative hydrocephalus in patients with posterior fossa tumor. Methods The clinical data of 241 patients who underwent resection of posterior fossa tumors were analyzed retrospectively, of which 14 patients were excluded because of postoperative complications with other systemic infections. The patients with posterior fossa tumor complicated with hydrocephalus were divided into preoperative lumbar cistern drainage 1（ PLCFD1） group（ 22 cases） and no preoperative lumbar cistern drainage 1（ NPLCFD1） group（ 45 cases）. 227 patients with posterior fossa tumors were divided into preoperative lumbar cistern drainage 2（ PLCFD2） group（ 43 cases） and no preoperative lumbar cistern drainage 2（ NPLCFD2） group（ 184 cases）. The clinical data of the two groups were compared and analyzed. Results In this group,67 patients with posterior cranial fossa tumor complicated with hydrocephalus, and the remission rate of hydrocephalus was 94. 0%.The remission rate of early postoperative hydrocephalus in PLCFD1 group（ 86. 4%） was significantly higher than that in NPLCFD1 group（ 62. 2%）（ P = 0. 043）. The postoperative intracranial infection rate in PLCFD2 group（ 23. 3%）was significantly lower than that in NPLCFD2 group（ 41. 3%）（ P = 0. 028）. There was no significant difference in antibiotic use time between PLCFD2 group[14（ 10. 75-20. 50） d]and NPLCFD2 group [17（ 13. 25-22. 75） d]（ P = 0. 134). Conclusions Surgical treatment of hydrocephalus is not recommended in patients with posterior cranial fossa tumors complicated with hydrocephalus, except for obvious acute intracranial hypertension and ineffective drug treatment; In the patients with subtotal resection or above, only a small number of patients with hydrocephalus need further surgical treatment. Proper lumbar cistern drainage during and after operation can promote the early clearance of inflammatory and bloody cerebrospinal fluid in patients with posterior fossa tumor complicated with hydrocephalus after tumor resection, so as to reduce the incidence of postoperative hydrocephalus and reduce the incidence of intracranial infection after posterior fossa tumor resection. [ABSTRACT FROM AUTHOR]

Objective: To explore the clinical application value and advantages of micro-neurosurgical treatment of cerebellopontine meningioma under "microendoscope combined". Methods The clinical data of 39 patients with cerebellopontine angle meningioma treated by the retrosigmoid sinus approach through the suboccipital were retrospectively analyzed. Among them, 11 cases used "micro-endoscopy combined" surgery (microendoscopy combined group), and 28 cases used simple microscope surgery (microscope group). Results In the combined microendoscopy group, 9 cases of simpson Ⅰ and Ⅱ resection were performed, and 2 cases were subtotal resection. The total tumor resection rate (Simpson grade I and II) reached 81.8%. In the microscope group, 19 cases of simpson Ⅰ and Ⅱ were resected, 5 cases were subtotal resection, 4 cases were partial resection. The total tumor resection rate (Simpson Class I and II) reached 67.9%. Both groups achieved facial nerve anatomy preservation. For meningiomas that involve the inner ear canal (IAC) and are located in front of or behind the inner ear canal, the retention rate of facial nerve function in the microendoscope combined group is 71.4%, and the retention rate of facial nerve function in the microscope group is 66.7%. Conclusion The "microendoscope combined" surgical method is an effective method for the treatment of cerebellopontine meningioma, especially for cerebellopontine meningioma that grows to IAC or extends to the tentorium. The combination of neuroendoscopy and microscope can complement each other, increase the total tumor resection rate, and reduce nerve function damage. [ABSTRACT FROM AUTHOR]

Objective To evaluate the efficacy of lung cancer screening in urban areas of Henan province by low-dose computed tomography (LDCT) from 2013 to 2017. Methods A cluster sampling method was used to select the residents of 40-74 years old in Henan province to investigate the risk factors and conduct lung cancer risk assessment. Subjects with high risk of lung cancer received LDCT for screening. Results A total of 179 002 residents completed the lung cancer risk assessment, and 35 672 subjects were identified as high risk of lung cancer, with a high risk rate of 19.93%. A total of 13 383 subjects with high risk received LDCT, and the screening rate was 37.52%. There were 786 cases diagnosed as positive nodules, and the detection rate was 5.87%. Among them, 755 cases of solid/partial solid nodule were ≥5 mm, 23 cases of non-solid nodules were ≥8 mm, 8 cases were intratracheal nodules, and 115 cases were diagnosed as suspicious lung cancer. The detection rate in males was 6.74%, which was higher than 5.02% in females. The detection rate was positively related with age (P<0.05). Conclusions The application of LDCT is a useful screening method which can elevate the early detection rate of positive nodules and other related diseases in lungs. In the future, males and older populations should be paid more attention to improve screening efficacy. [ABSTRACT FROM AUTHOR]

Confining pressure has a great effect on the internal microstructure of the rock,and results in a change in wave impedance,which affects the propagation attenuation laws of the stress wave in the porous rock subjected to high stress.In order to investigate the effect of confining pressure on the characteristics of stress wave propagation in rock,the relationships between both reflection coefficient and transmission coefficient with the wave impedance of rock were established based on one dimensional stress wave theory. Then the short and long rock specimens were made of red sandstone,and the experiments of stress wave propagation in specimens under different confining pressures were carried out based on the modified Split Hopkinson Pressure Bar( SHPB).Also,the experimental longitudinal wave velocities,wave impedances,reflection coefficients and transmission coefficients of rock under different confining pressures were analyzed.Based on the empirical relationship between wave impedance and confining pressure,and the theoretical relationship between wave impedance and transmission coefficient,the theoretical transmission coefficients under different confining pressures were obtained and compared with experimental values.The comparison shows that the differences between theoretical and experiment values were very small,and verifies the theoretical analysis of transmission and reflection coefficients are valid.The influence laws of confining pressure on the stress wave propagation along red sandstone were obtained by the comprehensive analysis of longitudinal wave velocity,wave impedance,transmitted and reflected coefficients of rock under different confining pressures.The results show that both the longitudinal wave velocity and wave impedance of rock specimen increase with the increase in confining pressure.With the increase of confining pressure,the transmission coefficient of short specimen increases,and the absolute value of reflection coefficient decreases,the transmission coefficient of long specimen,however,decreases gradually.The variation trends of both the reflection coefficient and trans-mission coefficient with confining pressure can be fitted with quadratic function.All of the above variation tendencies show that the increase of confining pressure decreases the attenuation of its amplitude. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To probe into the operating mode of clinical pharmacists in pharmaceutical care for patients with ovarian hyperstimulation syndrome(OHSS). METHODS: Clinical pharmacists conducted specific pharmaceutical care of medication guidance for patients according to standardize pharmaceutical care methods.RESULTS: Through reinforcing medication monitoring and reforming, clinical pharmacists conducted medication guidance and propaganda for patients with OHSS and complicated with gestation, so that to ensure safe drug application. CONCLUSIONS: Patients with OHSS need pharmaceutical care during treatment, especially those patients complicated with gestation, in order to supervise safe medication during early pregnancy. [ABSTRACT FROM AUTHOR]

Interdisciplinary integration can not only broaden the students'thinking and vision, stimulate the awareness of innovation and motivation of study, but also contribute to the cooperative development of disciplines in todays high-level university and the training mechanism for innovative personnel. Through the research of innovative experimental system based on interdisciplinary integration, the construction and implementation of interdisciplinary innovative experimental platform are explored. This platform will not only provide a good platform to support for cross-disciplinary experimental teaching and scientific research, but also help to promote the cultivation of innovative talents and the further development of open-style and first-class disciplinary system construction. [ABSTRACT FROM AUTHOR]

Objective: To study whether Lipoteichoic Acid of Lactobacillus bulgaricus(LBG-LTA) inhibits Toll-like receptor 4(TLR4) pathway in rat Kupffer cells by decreasing lymphocyte-specific protein tyrosine kinase(Lck) in lipid rafts. Methods: Ten male Wistar rats, 2 months old, 250~300 g, were killed for the isolation of Kupffer cells. Kupffer cells were treated by lipopolysaccharide(LPS) with or without a pretreatment of LBG-LTA, methyl-β-cyclodextrine(MβCD) or PP2(Lck inhibitor). Membrane-cytosol protein and nuclear protein were extracted from Kupffer cells. Lipid rafts and non-raft fractions were extracted from membrane-cytosol protein via sucrose density gradient centrifugation. TLR4, TANK binding kinase-1(TBK1) and Lck in rafts and non-raft fractions as well as nuclear factor-κB(NF-κB) in nuclear protein were measured by Western blot. Tumor necrosis factor-α(TNF-α) and interleukin-1β(IL-1β)were quantified by ELISA. Results: The majority of TLR4 and Lck up-regulated by LPS was detected in rafts(the comparison of level of TLR4 or Lck in rafts between LPS and control group: 0.95 0.23 vs 0.012 0.0023, 1.05 0.26 vs 0.022 0.0052, P<0.05). However, TBK1 increased by LPS was mainly found in non-raft fractions(the comparison of TBK1 level in non-raft fractions between LPS and control group: 1.02 0.21 vs 0.048 0.011, P<0.05). NF-κB in nuclear protein, TNF-α and IL-1β were obviously augmented by LPS(the comparison of level of NF- B, TNF-α or IL-1β between LPS and control group: 0.78 0.16 vs 0.076 0.014, 189.2 27.1 vs 5.62 0.82, 131.6 18.8 vs7.24 1.14, P<0.05). Similar to MβCD or PP2, LBG-LTA also obviously inhibited these effects of LPS(the comparison of level of TLR4 or Lck in rafts, TBK1 in non-raft fractions, NF- B, TNF-α or IL-1β between LTA+LPS and LPS group: 0.15 0.036 vs 0.95 0.23, 0.170.052 vs 1.05 0.26, 0.25 0.062 vs 1.02 0.21, 0.17 0.035 vs 0.78 0.16, 32.2 4.37 vs 189.2 27.1, 23.4 3.29 vs 131.6 18.8, P<0.05). Conclusions: LBG-LTA inhibits LPS-activated TLR4 pathway in rat Kupffer cells by decreasing Lck in rafts. [ABSTRACT FROM AUTHOR]

Objective: To determine whether Lipoteichoic Acid of lactobacillus bulgaricus(LBG-LTA) inhibits Toll-like receptor4(TLR4) pathway in Kupffer cells isolated from rats. Methods: Ten healthy male Wistar rats, 2 months old, 250~300 g, were killed for the isolation of Kupffer cells. Isolated Kupffer cells were treated with lipopolysaccharide(LPS, 1 EU/m L) with or without LBG-LTA(0.1, 1 or 10 μg/m L) pretreatment. The expression of TLR4, TANK binding kinase-1(TBK1) and activated nuclear factor-κB(NF- B) in Kupffer cells was measured by Western blot. The production of tumor necrosis factor-α(TNF-α) and interleukin-1β(IL-1β) was quantified by ELISA. Results: The LPS-induced expression of TLR4, TBK1 and activated NF- B and production of TNF-α and IL-1β in isolated Kupffer cells were significantly inhibited by LBG-LTA pretreatment in a dose-dependent manner(P<0.05). Conclusions: LBG-LTA inhibits LPS-activated TLR4 pathway in Kupffer cells of rats in a dose-dependent manner. [ABSTRACT FROM AUTHOR]