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目的观察老年呼吸衰竭伴慢性肺心病患者血小板活化因子(PAF)水平和血小板功能的变化。方法选取老年呼吸衰竭伴慢性肺心病患者70例为A组,另选取同期慢性肺心病患者70例为B组,健康体检者70例为对照组,应用血小板聚集仪检测血浆中PAF水平,检测血小板膜释放功能(GMP140)、血小板黏附功能(PADT)、血小板聚集功能(PAg T)水平,并对患者进行动脉血气检测。结果 A组、B组、对照组PAF水平分别为(178.3±19.4)、(152.8±1.5)、(132.1±8.6)μg/L,三组间两两比较,P均<0.05。PADT、PAg T和GMP140水平比较A组>B组>对照组(P均<0.05)。A组、B组、对照组动脉血氧分压分别为(47.5±8.2)、(54.2±7.6)、(60.1±9.3)mm Hg,动脉血二氧化碳分压分别为(50.2±8.6)、(44.2±7.6)、(36.3±8.5)mm Hg,三组间两两比较,P均<0.05。结论老年呼吸衰竭伴慢性肺心病患者PAF水平升高,血小板黏附、聚集、膜释放功能增加。 [ABSTRACT FROM AUTHOR]

目的　观察宫颈癌组织中人类黑色素瘤相关抗原Ａ３（ＭＡＧＥ-Ａ３）的表达变化，分析其与肿瘤临床病理参 数及预后的关系。方法　收集宫颈癌组织７６例、宫颈上皮内瘤变（ＣＩＮ）组织４０例、正常宫颈组织标本２５例，采用 免疫组化ＳＰ法检测ＭＡＧＥ-Ａ３，分析ＭＡＧＥ-Ａ３表达与患者年龄、ＦＩＧＯ分期、组织病理学分级、淋巴结转移及阴道 残端癌累及的关系。收集７０例宫颈癌患者的术后随访资料，采用Ｋａｐｌａｎ-Ｍｅｉｅｒ生存曲线分析ＭＡＧＥ-Ａ３表达与患 者预后的关系。结果　宫颈癌组织、ＣＩＮ组织、正常宫颈组织中ＭＡＧＥ-Ａ３阳性表达率分别为５３．９４％、７．５０％、０， 组间两两相比，Ｐ＜０．０５。ＦＩＧＯ分期Ⅱａ１期宫颈癌组织中ＭＡＧＥ-Ａ３阳性表达率高于Ⅰ期者（Ｐ＜０．０５）。病理 分级为Ｇ１、Ｇ２、Ｇ3 的宫颈癌组织中ＭＡＧＥ-Ａ３阳性表达率逐渐增高（Ｐ＜０．０５）。有淋巴结转移的宫颈癌组织中 ＭＡＧＥ-Ａ３阳性表达率高于无淋巴结转移者（Ｐ＜０．０５）。ＭＡＧＥ-Ａ３低表达组患者５年生存率为７８．１％（２５／３２），高 表达组患者５年生存率为４４．７％（１７／３８），两者相比，Ｐ＜０．０５。结论　宫颈癌组织中ＭＡＧＥ-Ａ３阳性表达率高于 ＣＩＮ组织和正常宫颈组织；ＭＡＧＥ-Ａ３高表达可能与宫颈癌的发生发展及不良预后密切相关。 [ABSTRACT FROM AUTHOR]

Cryoablation plays an important role in the treatment of non-small cell lung cancer in addition to dehydrating, rupturing and necrotizing tumour cells at low temperature, but also by generating anti-tumour immune responses. In recent years, immunotherapy has been effective in the treatment of NSCLC. So is there a synergistic effect between cryoablation and immunotherapy in NSCLC treatment? This article reviews the application of cryotherapy, immunotherapy and combination therapy in the treatment of NSCLC. [ABSTRACT FROM AUTHOR]

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Copyright of China Harbour Engineering is the property of Editorial Office of China Harbour Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to explore the effects of nitrogen(N)deficiency and compensation of nitrogen(N)nutrient on growth and root morphology of banana. In this experiment, two main cultivated variety genome types(AAA and ABB)were used as materials, plant height, leaf length, leaf width, number of new green leaves, fresh weight and dry matter mass of shoot and roots, root length, root surface area and root volume were studied by using quartz sand matrix culture combined with N deficiency and compensation treatment. The results were as follows:(1)The plant height, leaf length, leaf width and number of new green leaves decreased significantly, after 30 d N deficiency of varieties Ⅰ and Ⅱ, dry matter mass of roots increased by 64.71% and 87.50%, and root-shoot ratio increased, total root surface area and volume increased by 4.38% and 11.85%,71.78% and 66.55%, respectively.(2)After 68 d N deficiency of varieties Ⅰ and Ⅱ, dry matter mass of the whole plant decreased by 33.74% and 42.04%, and there was no significant differences between the deficiency treatment and the conventional treatment. The change trend of root morphological parameters was consistent with that of mild deficiency.(3)After the deficiency, N supply was compensated, the symptom of N deficiency disappeared, and the plant growth indexes returned to normal level. The dry matter mass of the varieties Ⅰ and Ⅱ increased by 51.22% and 52.38%, and the root-shoot ratio was significantly higher than that of the conventional treatments. Roots tended to grow in normal shape, and total root volume increased by 61.80% and 45.92%, respectively. The dry matter mass and volume of roots increased significantly than the conventional treatments and the plant growth vigor was better when the N compensation was timely after mild N deficiency. To sum up, the method of deficiency compensation can be comprehensively used in the production to promote the growth of banana seedlings in the field. [ABSTRACT FROM AUTHOR]

Objective: To investigate the application value of estrogen receptor (ER) and cox-2 (cox-2) in the diagnosis and diagnosis of ovarian cancer. Methods: Paraffin embedded ovarian tissue sections of 120 patients diagnosed by pathology and operation were selected, including 54 cases of ovarian cancer and 66 cases of benign ovarian tumors. The expression of ER and cox-2 was detected by immunohistochemistry. Results: The positive expression rates of ER and cox-2 in ovarian cancer tissues were higher than those in benign ovarian cancer tissues (P<0.05). Ⅳ period ER positive expression rate was higher in ovarian cancer tissue Ⅰ period (P<0.05), compared with the rest of the groups were no difference(P>0.05). There were no difference in the cox-2 positive expression rate between groups (P>0.05). Cox-2 positive expression in Ⅱ ovarian cancer tissue level rate was higher than the level Ⅰ (P<0.05), while the rest of the way were no difference (P>0.05). ER positive expression rate in tissues with metastatic ovarian cancer was higher than that without metastasis (P<0.05). The positive expression rate of cox-2 in the tissues with metastatic ovarian cancer was not difference compared with that without metastasis (P>0.05); The expression of ER and COX-2 in ovarian cancer with metastasis and immunohistochemical score (IHS) were higher than those without metastasis (P<0.05). Conclusion: The expression of ER and COX-2 in ovarian cancer tissue and benign ovarian tumor tissue was gradually up-regulated, and the expression of ER and COX-2 in ovarian cancer tissue was higher than that in benign ovarian tumor tissue. ER expression is correlated with pathological stage and metastasis of ovarian cancer, and COX-2 expression is correlated with histological grade of ovarian cancer. The prediction of ovarian cancer disease and COX-2 expression are complementary, which can be used as biological indicators to judge and evaluate the degree of malignancy of ovarian cancer. [ABSTRACT FROM AUTHOR]

Shaanxi Province is the main area of China’s soil erosion andsediment production area of the Yellow River. In order to provide theoretical reference for soil erosion control in Shaanxi Province and the Yellow River Basin, based on the data of monthly precipitation, soil attributes, NDVI, DEM and land use, the RUSLE model was used to calculate the soil erosion modulus and the maximum change rate method was used to identify the main driving factors of the temporal and spatial changes of soil erosion intensity in Shaanxi Province from 2000 to 2015. The results show that the distribution of soil erosion in Shaanxi Province has strong heterogeneity, among which severe and very strong erosion are mainly distributed in northern Shaanxi area and a few in the northern part of Guanzhong area; from 2000 to 2015, the soil erosion intensity in northern Shaanxi shows an overall downward trend. Among them, the soil erosion intensity in northern Shaanxi area has been on a downward trend and the Guanzhong and southern Shaanxi areas have shown a trend of first rising and then falling; the main driving factor of the temporal change of soil erosion intensity in Shaanxi Province is vegetation cover from 2000 to 2015, and the co-driven rainfall erosivity and vegetation cover from 2000 to 2005, and rainfall erosivity from 2005 to 2015; the main driving factors for the spatial changes of soil erosion intensity in Shaanxi Province are vegetation cover and topography. Among them, Yulin, Tongchuan, Baoji, Xi’an, Shangluo, Ankang and Hanzhong are mainly driven by vegetation coverage, Weinan and Xianyang are driven by topography and Yan’an is driven by rainfall erosivity. The maximum change rate method can be used to identify the main driving factors of the temporal and spatial changes of soil erosion, but it is more sensitive to the extreme value of rainfall erosivity when identifying the main driving factors of temporal changes and the time step size should be expanded as much as possible to eliminate its influence. [ABSTRACT FROM AUTHOR]

BACKGROUND: Up to now, there is no literature on the relationship between blood laboratory tests and the course of nontraumatic osteonecrosis of femoral head in different stages. It is necessary to further explore and analyze so as to better clarify the influencing factors of nontraumatic osteonecrosis of femoral head. OBJECTIVE: To analyze the relationship between blood laboratory indicators and the course of nontraumatic osteonecrosis of the femoral head by the Association Research Circulation Osseous (ARCO), thus exploring the influencing factors of blood laboratory indicators on the course of nontraumatic osteonecrosis of the femoral head. METHODS: This study used a retrospective study design. A total of 2 103 patients with osteonecrosis of the femoral head were retrieved from Wangjing Hospital of China Academy of Chinese Medical Sciences database, and 1 075 patients with nontraumatic osteonecrosis of the femoral head were ultimately included based on inclusion and exclusion criteria. Patient age, gender, body mass index, and blood laboratory test results were collected. Blood laboratory tests included low-density lipoprotein, total cholesterol, triglycerides, high-density lipoprotein, apolipoprotein β, apolipoprotein α1, uric acid, total protein quantitative, alkaline phosphatase, activated partial thromboplastin time, prothrombin time, prothrombin time International Normalized Ratio, prothrombin time activity, fibrinogen quantitative, coagulation time of thrombin, D-dimer, total iron binding capacity, and platelet count. The indicators of patients with different age groups and different ARCO stages were compared, and multiple Logistic regression analysis was applied to explore the influencing factors of ARCO stages in osteonecrosis of the femoral head. RESULTS AND CONCLUSION: (1) There were statistical differences in total cholesterol, uric acid, prothrombin time, prothrombin time International Normalized Ratio, and D-dimer among ARCO stages in the young group (P < 0.05). Among young patients in ARCO stage II, total cholesterol levels were higher than those in ARCO stage III (P < 0.05). Uric acid levels in ARCO stage IV were higher than those in ARCO stage II and III (P < 0.05). Prothrombin time and prothrombin time International Normalized Ratio were shorter in ARCO stage IV and II than in ARCO stage III (P < 0.05). D-dimer levels were higher in ARCO stage III and IV than in ARCO stage II (P < 0.05). (2) There were statistically significant differences in high-density lipoprotein, coagulation time of thrombin, and D-dimer among ARCO stages in the middle-aged group (P < 0.05). Among middle-aged patients in ARCO stage IV, high-density lipoprotein levels were higher than those in ARCO stages II and III (P < 0.05). Coagulation time of thrombin was shorter in ARCO stage IV than in ARCO stage III (P < 0.05). D-dimer levels were higher in ARCO stages IV than in ARCO stages II and III (P < 0.05). (3) The uric acid, activated partial thromboplastin time, D-dimer, and platelet count in the elderly group showed statistically significant differences (P < 0.05). The uric acid level in ARCO stage IV was higher than that in ARCO stage II and III patients in the elderly group (P < 0.05), while the activated prothrombin time in ARCO stage II patients was shorter than that in ARCO stage III patients in the elderly group (P < 0.05). The D-dimer level in ARCO stage III and IV patients was higher than that in ARCO stage II patients in the elderly group (P < 0.05). The platelet count in ARCO stage IV was lower than that in ARCO stage III patients in the elderly group (P < 0.05). (4) Multiple logistic regression analysis showed that total cholesterol and platelet count may be protective factors for course of nontraumatic osteonecrosis of the femoral head, while D-dimer, uric acid, overweight, and young and middle age may be risk factors for course of nontraumatic osteonecrosis of the femoral head. (5) It is indicated that total cholesterol, high-density lipoprotein, uric acid, prothrombin time, prothrombin time International Normalized Ratio, and D-dimer are statistically significant among patients with different ARCO stages. Total cholesterol and platelet count may be protective factors for the course of nontraumatic osteonecrosis of the femoral head, while D-dimer, uric acid, overweight, and middle-aged and young age groups may be hazard factors for the course of nontraumatic osteonecrosis of the femoral head. [ABSTRACT FROM AUTHOR]

Diarrhea is one of the main causes that leads to the death of wild pangolin in captivity. In order to understand the cause and pathogenesis of diarrhea, two rescued Chinese pangolins (Manis pentadactyfa) with diarrhea were treated with non-antibiotic therapy, and the diversity and composition of the fecal bacterial and fungal microbiota determined by high throughput sequencing were compared before and after treatment. The results showed that dietary supplementation of astringent drug (montmorillonite) and Bacicillus subtilis could alleviate the symptoms of diarrhea effectively, and the color and form of feces were changed from yellow paste to black strip. The total number of OTUs and relative abundance indices (ACE and Chao 1) of fecal bacteria were decreased after treatment, while the total number of OTUs and Chao 1 index of fungi were increased, but Alpha diversity of both bacteria and fungi increased did not change much before and after treatment. However, a signi1icant deviation of bacterial or fungal flora occurred be1ore and after treatment by Beta diversity analysis. The dominant bacterial phylum was basically the same before and after trea1ment. After treatment, the proportion of Lactobacillus decreased significantly and Clostridum sensu stricto 1 increased significantly. After treatment, the proportion of Ascomycota increased significantly and Basidiomycota decreased significantly; the proportion of Condensascus increased significantly and Trichosporon decreased obviously. In conclusion, the intestinal flora of the two Chinese pangolins changed significantly in the process of food conversion. After non-antibiotic therapy, the flora inormed a new steady state, and the intestinal absorption capacity was enhanced. [ABSTRACT FROM AUTHOR]

Thermal properties of frozen soil can be measured to evaluate the engineering construction and agricultural production. However, it is still challenging to determine the thermal properties of frozen soil using a dual-probe heat pulse sensor (DPHP). The thermal pulse can cause the ice around the heating probe to melt during DPHP measurement. The commonly- used analytical solution can only consider the heat conduction, resulting in the less accurate measurement on of the thermal conductivity (λ) and specific heat (Cv ) at −5 ℃ to 0 ℃. The purpose of this study is to test the feasibility of finite element simulation for the frozen soil DPHP. COMSOL simulation was carried out to consider the latent heat and temperature of phase transition in the measurement process of DPHP. The two-dimensional transient fluid module was used for simulation. The three-dimensional of DPHP experiment was simplified to the heat transfer in two-dimensional cylindrical coordinates. The 150 mm × 150 mm square was constructed as the study area, where was approximated the DPHP probe with a 0.6 mm circle (ignoring internal probe padding and needle body material), and spaced the probe by 6 mm. The boundary of the study area was set as the adiabatic boundary, the boundary of the circular heat source was the heat flux boundary, which was set as 48.51 W/m, and the heating time was set as t0 = 8 s, respectively. The parameter settings were consistent with the experimental process. The nonlinear relationships between thermal conductivity and specific heat capacity with temperature was were calculated using the nonlinear relationship between liquid water content and temperature as studied by He et al. 2015. These relationships were then set as the thermal conductivity and specific heat capacity of the frozen soil model. Four phase change temperatures were at −0.05-0.05, −2- 0, −1.5-−0.5, and −0.5-0 ℃, corresponding to phase change intervals of 0.1, 2, 1, and 0.5 ℃, respectively. Four geometric shapes were constructed around the key solving region (around the DPHP probe), each of which the center was located at the center of the heating probe and side lengths of 5, 10, 15, and 20 mm. The reason was that the uniformly refined grids over the domain were resulted in the high computational costs and large memory usage during simulation. The grid was refined at the boundaries of these geometric shapes, in order to achieve the higher solving accuracy. An infinite line heat source (ILS) and real permafrost measurements were used to evaluate the COMSOL simulation. Three COMSOL simulation models were compared with the ILS model and measured with/without considering phase transition and temperature. The results show that: 1) The COMSOL simulation was in better agreement with the ILS model without considering the phase transition. When the initial soil temperature was ranged from 0 ℃ to −1 ℃, the ILS model was significantly deviated from the experimental measurement (R2 < 0.0013). At the same time, the presence of the solid-liquid moving interface caused it to be invalid in the ILS model using single-phase heat transfer, when the temperature was close to 0℃. 2) The deviation of simulation from experimental data was significantly reduced to consider the phase transition occurrence and temperature. When the phase transition temperature was −1.5-−0.5 ℃, the correlation between the simulated and the measured value (R² > 0.7) was significantly higher than that between the ILS model and the measured value (R² < 0.001 3). Therefore, the heat transfer of transient melt phase transition can be effectively performed on COMSOL simulation. The more accurate measurement of frozen soil thermal properties was achieved, compared with the current mainstream traditional single-phase model. 3) COMSOL simulation can be used to predict the measurement of frozen soil by DPHP, where the liquid water content was obtained in the process of freeze-thaw at the interval of phase transition. The finding can provide the a new idea to measure the thermal properties of frozen soil in the field. [ABSTRACT FROM AUTHOR]

To analyze the aroma quality characteristics of different varieties of banana fruits, and to provide reference for the evaluation of banana fruit quality and the breeding of new varieties. [Method] Using headspace solid-phase microextraction combined with gas chromatography-mass spectrometry (GC-MS) technology to analyze 2 genome types of bananas (ABB genotype powder banana and AAA genotype ordinary banana) and 7 varieties (ABB genotype) Jinfen No. 1, 30b, 32b, 35b and 55b and AAA genotype Guijiao No. 6 and Baodao banana) the aroma components of fruits at the same ripening stage were separated, and their quality characteristics were determined and analyzed. [Results] A total of 48 volatile aroma substances were detected from 7 varieties of banana fruits, including 24 esters, 9 carbonyl compounds, alcohols, acids, phenols, and other compounds. The relative content accounts for 33.51% to 72.66% of the total content of aroma substances. It is the main component of banana fruit aroma substances. Its key components are isoamyl acetate, isoamyl isobutyrate, butyl butyrate and ethyl caproate, etc. The characteristic aroma substances of yellow ripe bananas; the types and contents of volatile aroma substances of ordinary banana varieties are more or higher than those of powder banana varieties. Among them, Baodao banana has the most types of aroma substances, and the relative content is the highest, with 41 species and 80.70% respectively. In the Fenjiao variety, 55b has the most types of aroma substances, with 34 species, and Jinfen 1 has the highest relative content of aroma substances, which is 66.20%. [Conclusion] The aroma substances of different varieties of banana fruits at the same mature stage are mainly esters such as isoamyl acetate, isoamyl isobutyrate, butyl butyrate and ethyl caproate, but the aroma components of mature fruits of common banana varieties are different. The types and contents are more or higher than those of Fenjiao varieties. Among Fenjiao varieties, 55b aroma substances are the most abundant, and Jinfen No. 1 has the highest relative content of aroma substances. [ABSTRACT FROM AUTHOR]

Rosa rugosa is a deciduous shrub belonging to Rosa L. in Rosaceae. It has a high ornamental value and commercial value, but its single color limits the development and utilization of rose and its application in landscape architecture. In order to explore the coloring substances of three different varieties of roses, ‘Rosa rugosa × Rosa sertata’, ‘Rosa Crimson Glory’ and ‘Rosa alba’, this study used ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-Q-TOF-MS) to detect the types and contents of flavonoids in petals. The KEGG database was used to enrich the differential metabolites, screen out the key metabolites, and analyze the correlation with the phenotypic value of flower color. The results were as follows: (1) A total of 58 metabolites were detected in the petals of three different color rose varieties, of which only one anthocyanin was cyanidin-3-O-glucoside, accounting for 30.45%. (2) K-means clustering analysis showed that a total of 12 key metabolites were annotated to the KEGG metabolic pathway. Among them, pinocembrin and myricetin were the main substances that determined the red color of ‘Rosa rugosa × Rosa sertata’ and ‘Rosa Crimson Glory’, and eriodictyol, luteolin and kaempferol were the main substances that determined the white color of ‘Rosa alba’. In conclusion, this study can provide a theoretical basis for the breeding of roses with specific colors and promote the application of roses in landscaping. [ABSTRACT FROM AUTHOR]

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The turbofan engine exhaust simulation is carries out for the flying wing UAV by the means of computational fluid dynamics. Firstly, the grid convergence study is performed with course, medium, and fine grid systems for the flying wing UAV through Reynolds-averaged Navier- Stokes equations and structured grid technology. Secondly, the change of the aerodynamic performance caused by the difference between the flying wing configuration with engine exhaust and without engine exhaust is discussed in the engineering design. Lastly, the turbofan engine exhaust effect is studied with three different nozzle pressure ratio conditions. The study shows that, the change of the configuration generated by engine exhaust makes the drag increased 6% -9% and pitching moment decreases.The engine exhaust has an effect on drag coefficient and pitching moment coefficient, and the influence quantities are varied with the nozzle pressure ratio. [ABSTRACT FROM AUTHOR]

[Objective] The purpose of the study was to clarify the impact of low temperature on the postharvest physiology and post ripening quality of different banana varieties, so as to provide a reference basis for improving the quality of overwintering banana fruits and enhancing the commercial value. [Method] Using Baodao banana and Guijiao 6 banana fruits with a maturity of 70% as the experimental materials, the banana fruits of the two varieties were treated at low temperature [ ( 6. 0 ± 0. 5 ) "C ] for 48 hours ( Tl, T2), and at room temperature [ (22. 0 ±0. 5) "C] as the control ( CKl, CK2). Under the same ripening conditions, the effects of low temperature treatment on the peel color, peel polyphenol oxidase ( PPO) and peroxidase (POD) activities, fruit intrinsic quality, and cell membrane permeability of the two banana varieties during post ripening were compared and analyzed. [Result]On the 3rd, 5th and 7th days of post ripening, the peel brightness ( L value) of Tl treatment was significantly higher than that of T2 treatment ( P < 0. 05, the same as below), which was 19. 7%, 22. 6% and 67. 7% higher respectively, and the L value of the peel of Tl and T2 treatments was significantly lower than that of CKl and CK2. On the 3rd of post ripening, the peel color ( H value) of T2 treatment significantly decreased by 9. 4% compared with that of Tl treatment. At this time, the green peel color of T2 treatment began to fade, and the color change of the peel of Baodao banana ( Tl, CKl ) was about 2 days later than that of Guijiao 6 ( T2, CK2) under the two treatment conditions. During the post ripening process, the peel PPO and POD activities of Tl and T2 treatments were significantly higher than those of CKl and CK2 treatments. On the 3rd and 5th day of post ripening, the peel POD activity of T2 treatment was significantly higher than that of Tl treatment by 22. 6% and 13. 1 % respectively. On the 3rd day of post ripening, the flesh hardness of Tl treatment was significantly higher than that of T2 treatment by 30.1 %. On the 1st and 3rd day of post ripening, the flesh hardness of CKl was significantly higher than that of CK2 by 37. 4% and 30. 0%, respectively, and the flesh hardness of T2 and CK2 treatments declined faster than that of Tl and CKl treatments. As the ripening process progressed, the soluble solid content of banana flesh in each treatment showed an upward trend, while the starch and vitamin C contents showed a downward trend. The growth of soluble solid content and the reduction of starch and vitamin C content were significantly slower in the Tl and T2 treatments than in the CKl and CK2, and the difference between the Tl and T2 treatments was not significant ( P > 0. 05). During the post ripening process, cell membrane permeability was significantly higher in T2 treatment than in Tl, CKl and CK2 treatments. [ Conclusion] The effects of low temperature on the degree of skin browning and increased cell membrane permeability of Guijiao 6 are more significant than those of Baodao banana. Under the two treatment conditions, the transformation of peel from green to yellow and the decrease of flesh hardness of Baodao banana are about 2 days later than that of Guijiao 6, and the storage and transportation quality of Baodao banana is better. The effects of low temperature on the soluble solids, starch and vitamin C content of the fruit of the two banana varieties are not significant. [ABSTRACT FROM AUTHOR]

This paper investigated the influence of rudder gap size on rudder efficiency of different rudder on flying wing aircraft using numerical simulation method. Result indicates that the rudder efficiency of inboard and outboard elevon is reduced because of rudder gap, and the bigger the gap size the more rudder efficiency decreases. Compared with that in no gap condition, the efficiency of split rudder is higher when rudder gap exists. The inboard and outboard elevon efficiency decrease caused by rudder gap can be attributed to the fact that the airflow of lower surface go through the gap to the upper surface, leading to the reduction of the pressure differences between the upper and lower surface, so as to block the main flow. The mechanism of split rudder efficiency increase at high deflection angle can be explained by the fact that high pressure airflow at the lower surface go through the gap and inject into reflux zone at upper surface. This flow phenomenon results in the reduced reflux range. [ABSTRACT FROM AUTHOR]

[Objective] The present paper aimed to clarify the effects of the interaction of paclobutrazol (PP333) with salicylic acid (SA), jas- monic acid(JA), chitosan (CTS) and benzothiadiazole (BTH) on the growth and disease resistance of banana seedlings, and provide refer- ence basis for the use of inducers to control Fusarium wilt of banana. [ Method] The tissue cultured cup seedlings of banana cultivar * Baodao banana' were used as experimental materials, and PP333 (treatment A) and four commonly used elicitors (treatment B, C, D and E) and double agent treatments (treatment A+B,A+C, A+D and A+ E) were sprayed on the leaves. The growth status, resistance to Fusarium wilt and defense enzyme activities of banana seedlings of each treatment were compared and analyzed by spraying water as the control (CK), combined with the inoculation method of root wounding. [Result 】30 days after treatment, the plant height of banana seedlings treated with va- rious drugs was significantly lower than CK (P<0.05, the same as below), and the stem diameter was generally higher than CK. Among them, the plant height of PP333 combined with BTH was the lowest in the double agent treatment, which was significantly reduced by 31. 84% compared with CK. The stem diameter of PP333 combined with JA was 20. 55% significantly higher than CK. The aboveground dry matter quality of banana seedlings treated with double agents was significantly lower than that of CK, with a decrease of 2.46% -5.74%, and the root dry matter quality was significantly increased by 39.02% -43.90% compared with CK. The disease index of banana F. wilt inthe seedling stage was significantly lower than that of CK, among which PP333 combined with BTH and CTS had a better effect on inducing resistance to banana F. wilt, reaching 57.63% and 50. 85% respectively. The effect of two treatments on the activity of resistance-related enzymes in banana seedlings was obvious. Among them, the activity of phenylalanine ammonia-lyase (PAL) of PP333 combined with BTH and CTS increased by 54.59% -101.69% and 42.09% -103. 50% respectively compared with CK, the activity of polyphenol oxidase (PPO) increased by 77.29% -228.77% and 66.07% -267.65% respectively, and the activity of peroxidase (POD) increased by 121. 82% -204. 16% and 54.31% -117.55% respectively. The activity of superoxide dismutase (SOD) increased by 107.45% -263.51% and 110.00%-301. 07% respectively, and CAT activity increased by 141. 95% -442. 16% and 192. 68% -304. 70% respectively. [Conclusion] The interaction of PP333 and the inducer can increase the activity of defense enzymes in banana seedlings, which has a good effect on strengthening seedlings and inducing disease resistance to banana F. wilt. In general, PP333 combined with BTH and CTS has the best induction effect, and has a prospect of production and application. [ABSTRACT FROM AUTHOR]

Objective To investigate the current status and related factors of clinicians in implementing blood transfusion notification obligations, in order to provide scientific basis for the formulation of measures to improve the quality of implementing the blood transfusion notification obligation.Methods Using the method of prevalence survey, a total of 144 clinicians who had received at least one red blood cell transfusion order from April 1 to June 30,2019 in a tertiary hospital were taken as the research objects, and the revised questionnaire about clinicians′ notification obligation of blood transfusion in British blood transfusion review was used as the survey tool, which mainly included the general situation of the research objects and the implementation of the notification obligations of 15 core blood transfusion items.The SPSS23.0 software was used for statistical analysis.Results 73.61%（106/144） clinicians had the time of implementing the notification of blood transfusion more than five minutes, which could effectively answer 75.00%（108/144） patients′ questions.There were significant differences in the proportion of clinicians′implementation of notification obligations of the blood transfusion items, among which 34.72%（50/144） clinicians had poor implementation of blood transfusion notification obligation（entries score less than 10 points）.The department, age, gender, professional and technical position, and working years had nothing to do with clinicians′ notification obligation of blood transfusion, and the differences were not statistically significant（P>0.05）.However, receiving transfusion training in clinical practice was an independent factor affecting the quality of transfusion notification obligation（OR=4.72,95%CI:1.71-13.02,P=0.003）.When implementing the obligation of notification, clinicians rarely notifed the relatively rare blood transfusion methods or infrequent transfusion risks, and did not fully notify the alternative treatment plan of blood transfusion.More than half of clinicians did not notify the patients that they could not donate blood within one year after transfusion.Conclusion The quality of clinicians′ implementing part of the notification obligation blood transfusion needs to be improved.Targeted systematic training is conducive to improving the quality of clinicians′ implementation of the notification obligation blood transfusion, so that patients can actively participate in blood transfusion decision-making, so as to improve the quality and safety of blood transfusion. [ABSTRACT FROM AUTHOR]

Objective To explore the application effect of precision oral grading nursing strategy on the chemotherapy-induced oral mucositis (CTOM) in the patients with acute leukemia receiving large-dose chemotherapy. Methods Total 110 patients with acute leukemia admitted and treated in this hospital from April 1, 2021 to March 1, 2022 were randomly divided into intervention group (n=55) and control group (n=55). The control group implemented the conventional oral nursing and the intervention group implemented the precision oral grading nursing. The changes of severity, effective prevention rate and the healing time of CTOM, self assessment of oral state and the patient satisfaction were compared between the two groups. Results The effective prevention rate, severity and healing time of CTOM during the oral mucosa whole process management in the intervention group were significantly lower than those in the control group (P <0.05);moreover, due to the decrease of the oral pain degree (VAS), the Oral Status Self-assessment (OMDQ) score in the intervention group was significantly higher than that in the control group (P <0.05), and the nursing satisfaction degree score in the intervention group was higher than that in the control group(P =0.005). Conclusion The implementation of precise grading oral nursing strategy for the patients with acute leukemia chemotherapy can effectively prevent the occurrence probability of CTOM, reduce the severity of CTOM, shorten the healing time and improve the quality of life of the patients [ABSTRACT FROM AUTHOR]

Under the background of global warming, high temperature weather occurs frequently in the Yangtze River Basin, which has become the primary problem seriously affecting the safe production of rice in this region. In order to clarify the effects of short-term high temperature on the spikelet opening dynamics and yield of different rice varieties during flowering period, the heat-resistant rice variety N22 and heat-sensitive rice variety YR343 were used as experimental materials and planted in pots. From the day of heading and blooming, the artificial climate chamber was used for temperature treatment, with 32℃/25℃ (day/night) as the control, 38℃/30℃ as the high temperature treatment, and continuous treatment for 7 days. Samples were taken on the 1st, 3rd, 5th, and 7th days of treatment to study the effects of high temperature stress on the opening dynamics, physiological characteristics of spikelets and yield of rice in different days of flowering. The results showed that: (1) the yield and seed setting rate of rice showed a decreasing trend after high temperature stress, and the reduction range was related to the duration of high temperature. After 7 days of high temperature treatment, the yield and seed setting rate of N22 decreased by 49.1% and 37.4%, and that of YR343 decreased by 85.1% and 65.3%, respectively. (2) The anther dehiscence rate and pollen activity of rice decreased to varying degrees after high temperature stress during flowering, and the longer the high temperature lasted, the greater the decrease. (3) The total amount of spikelet opening of rice was significantly reduced under high temperature stress, in N22 and YR343, by 33.3% and 65.5%, respectively. The flowering peak and peak appearance time of rice changed under high temperature stress. Compared with the control, the flowering peak ratio of N22 and YR343 decreased by 0.5% and 2.8%, respectively, and the flowering peak of N22 appeared 1 h earlier, while that of YR343 did not change. And under the high temperature coercion, YR343 has a shortened flowering period. (4) The changes of the physiological indices of rice spikelets under high temperature stress were as follows: the contents of soluble protein, soluble sugar and proline generally decreased; the contents of malondialdehyde and hydrogen peroxide increased; the activity of antioxidant enzymes showed a trend of first increasing and then decreasing. In summary, the low seed setting rate is the main reason for the reduction in rice yield. High temperature stress leads to the reduction of rice yield, mainly by changing the spikelet opening dynamics and its physiological characteristics, reducing the anther dehiscence rate and pollen activity, and thus reducing the seed setting rate. [ABSTRACT FROM AUTHOR]

Objective To explore the distribution of TCM symptoms in people with different bone masses by TCM Symptoms Identification tools in High-risk Population of Osteoporosis, and to provide clinical evidence for TCM identification of people at high risk of osteoporosis. Methods This research group recruited subjects from September 2020 to lune 2021, collected clinical data of subjects and the result of the TCM symptom identification questionnaire for people at high risk of osteoporosis, entered the database, and used the chi-square test to determine the occurrence of TCM symptoms The frequency is compared, and the differences in the distribution of TCM symptoms among people with different bone masses are analyzed. Results The data of 293 subjects and the result of the questionnaire were analyzed. Among them, 124 had reduced bone mass, 137 had normal bone mass, and 32 had osteoporosis. 2 Among them, the waist and knees are sore (40.32% vs 27. 74%), the height becomes shorter (52.42% vs 36. 50%). lower extremity spasm (35.48% vs 17. 52%), fatigue Fatigue (29.84% vs 18. 25%), dreaminess (27.42% vs 14.60%), insomnia (37. 10% vs 21. 90%), tinnitus (31. 45% vs 17. 52%), forgetfulness (54.03% vs 32. 85%) dry mouth and dry throat (39. 52% vs 25.55%), blurred vision (45. 16% vs 29.93%) dry eyes (43.55% vs 27.74%), a total oil1 TCM symptoms appear more frequently in the osteopenia group than in the normal bone mass group, with statistical differences. 3 Soreness of the waist and knees (40.32% vs 56.25%), chills (40.32% vs 56. 25%), tinnitus (31.45% vs 46.88%), low back pain (48. 39% vs 62. 5%), dizziness (23.39% vs 37.5%), loss of teeth (29.84% vs 3. 75%), dreaminess (27.42% vs 40.63%), dry eyes (43. 55% vs 56. 25%), excessive nocturia (21. 77% vs 34. 38%), anorexia (8. 06% vs 18. 75%), heel pain (14.52% vs 25%), irritated hands and feet (15. 32% vs 25%), withered hair (6.45% vs 15.63%), body pain (19. 35% vs 28. 13%), irritability (25. 81% vs 34. 38%), weight loss (8.06% vs 15. 63%). back pain (37.9% vs 43. 75%), severe cold pain (37.9% vs 43.75) %), dizziness (25.81% vs 31.25%), lower limb spasm (35. 48% vs 40. 63%), lower limb sleepiness (33.06% vs 37. 5%), forgetfulness (54. 03% vs 56. 25%) yellow facial muscle thinness (4. 03% vs 6.25%), limb numbness (17.74% vs 18.75%), a total of 25 TCM symptoms appeared in the osteopenia group less frequently than in the osteoporosis group, but did not reach a statistical difference; The frequency of shortness of breath (20. 97% vs 46. 88%) in the osteopenia group is lower than that in the osteoporosis group, which is statistically different. Conclusion People with different bone mass have different frequency and frequency of TCM symptoms, and there is a trend of increasing TCM symptoms in different people with normal bone mass and bone mass reduction to osteoporosis. TCM symptoms can be used to identify high risk of osteoporosis. For the population. TCM symptom identification tools have certain value for screening high-risk populations of osteoporosis. [ABSTRACT FROM AUTHOR]

The experiment was to study the pretreatment method of bagasse cellulose, optimize the composition of cellulase system and increase the amount of enzyme production. Bagasse cellulose was pretreated by microwave, phosphoric acid and steam explosion. The results showed that cellulase production and hemicellulase activity of Fusarium oxychlamycline HML278 were increased, the enzyme activity of filter paper was increased by 1.02 times than that of untreated material, and the enzymatic hydrolysis of glucose was increased by 100% compared with that of untreated bagasse. Aspergillus oryzae HML366 could produce β-glucosidase with high transferring-activity to synthesize gentiose. Gentiose could induce cellulase production from Fusarium chlamychii HML278. Fusarium oxychlamycline HML278 and Aspergillus oryzae HML366 had good compatibility, and the enzyme activity of filter paper was increased by 83.62% compared with Fusarium oxychlamycline HML278 and 93.09% compared with Aspergillus oryzae HML366. The study indicates that the mixed culture of Aspergillus oryzae HML366 and Fusarium oxychlamyclum HML278 is better than that of single strain. [ABSTRACT FROM AUTHOR]

【Objective】The present paper aimed to the effects of phosphorus application rate on switchgrass growth and soil nutrients in saline-alkali soil, in order to determine the appropriate amount of phosphorus, which provided a theoretical basis for saline-alkali soil improvement and high yield and high efficiency cultivation of switchgrass in Yinbei area of Ningxia.【Method】In Yinbei area of Ningxia, switchgrass, an energy crop, was used as material to study the effects of different treatments on the growth, soil saline-alkali content and nutrient absorption and utilization of switchgrass by setting 0,30 and 90 kg/hm² of phosphorus fertilizer（expressed as P0, P30 and P90, respectively） through field experiments.【Result】At the mature stage of switchgrass, the soil salinity and alkali content in 0-100 cm soil layer of each treatment were all P0>P30>P90, and the soil organic matter, available phosphorus and alkali-hydrolyzable nitrogen contents were all P90>P30>P0. Compared with P0, P90 treatment significantly reduced the soil salinity and alkali content and increased the nutrient content. Phosphorus application contributes to the growth of switchgrass, which promoted the absorption and utilization of nitrogen and phosphorus, and improved the accumulation of aboveground dry matter. Under three phosphorus levels, soil nitrogen balance of payments were deficit, and soil phosphorus balance was surplus only under P90 treatment.【Conclusion】The comprehensive results showed that under the conditions of this experiment, 90 kg/hm² P application rate could not only ensure the good growth of switchgrass and obtain high biomass yield, but also alleviate the saline-alkali pressure, improve the soil nutrient status and maintain a reasonable balance of nitrogen and phosphorus. [ABSTRACT FROM AUTHOR]

In the experiment, pectin was used as the sole carbon source, and a pectinase-producing strain JYJ was selected from the high-efficiency wine cake powder. The rich passion fruit peel was used as the fermentation raw material to conduct single-factor experiments and orthogonal experiments to optimize the culture conditions. The results showed that it was identified as Lysinibacillus fusiformis after morphological observation and 16S rDNA sequence alignment. The optimal combination of fermentation conditions for enzyme production were inoculation amount 6%, fermentation time 72 h, fermentation culture temperature 30 ℃, fermentation medium initial pH value 6.5. The experiment indicates that the pectinase activity measured under this condition was 121.46 U/mL, which was 1.49 times higher than the initial fermentation enzyme activity of 81.43 U/mL. [ABSTRACT FROM AUTHOR]

Objective To explore the effect of the expression changes of O-fucosyltransferase 1（POFUT1）in the tumor tissues on the prognosis of tumor patients and its mechanism. Methods Combined with the pan-cancer data sets obtained from the TCGA database and the GTEx database, we used the GEPIA2 and TIMER2 to compare the expression levels of POFUT1 in various types of tumors and paired normal tissues, and selected the tumor types with statistical differences. The prognosis of the above tumor patients with different POFUT1 levels was compared. The TIMER database and the estimate software package were used to screen the tumors with the strongest correlation between POFUT1 and the level of immune cell infiltration, and then we analyzed the correlations between POFUT1 and the above-mentioned tumor tissue matrix score, immune cell infiltration score, and comprehensive score. Further, the String database and GEPIA2 were used to screen POFUT1-related genes, and the functional enrichment analysis of POFUT1 and its related genes was carried out based on the DAVID database. Results Compared with the paired normal tissues，the expression difference of POFUT1 was statistically significant in the cholangiocarcinoma，colon cancer，breast cancer，esophageal cancer，glioblastoma，head and neck squamous cell carcinoma，renal chromophobe carcinoma，low-grade brain glioma，hepatocyte cancer， lung adenocarcinoma，lung squamous cell carcinoma，pancreatic cancer，rectal adenocarcinoma，skin melanoma，gastric cancer，gastroesophageal cancer and thyroid cancer（all P<0. 05）. Seven tumor types showed differential expression of PO⁃ FUT1 in the TIMER2 and GEPIA databases（colon cancer，esophageal cancer，glioblastoma，head and neck squamous cell carcinoma，renal chromophobe carcinoma，rectal adenocarcinoma，and gastric cancer）. In the renal clear cell carcinoma and rectal adenocarcinoma，the overall survival time of the high POFUT1 expression group was higher than that of the low POFUT1 expression group（P<0. 05）. In the low-grade brain glioma，mesothelioma，and uveal melanoma，the overall survival time of low POFUT1 expression group was higher than that of the high POFUT1 expression group（P<0. 05）. The three tumors with the strongest correlation between POFUT1 and immune cell infiltration levels were low-grade glioma，colon cancer，and bladder urothelial carcinoma. The expression level of POFUT1 was related to the stroma，immune cell infiltration and comprehensive score of low-grade brain glioma tissues and the immune infiltration score of colorectal cancer tissues（all P<0. 05）. The enriched pathways of POFUT1 and its related genes were mainly protein binding and RNA binding pathway, serine-related enzyme pathway，apoptosis pathway，and Notch signaling pathway. Conclusions The ex⁃ pression level of POFUT1 increases in 17 types of tumors. Renal clear cell carcinoma and rectal adenocarcinoma with high POFUT1 expression have better prognosis，while low-grade brain glioma，mesothelioma and uveal melanoma with low ex⁃ pression have better prognosis. POFUT1 may affect the prognosis of tumor patients by regulating the level of tumor immune infiltration and signaling pathways such as protein binding，RNA binding and Notch signaling pathway. [ABSTRACT FROM AUTHOR]

目的 研究非计划性重返重症监护病房(ICU)视角下外科护士危重症护理能力。方法 选取2018年1月至 2019年11月48 h内非计划重返ICU的成人外科患者41例;通过病历判读、文献查阅及半结构式访谈,找出外科病区非计划重 返ICU的护理相关因素,进行危重症护理能力考试并分析。结果 通过病历判读及访谈,归纳出非计划重返ICU的外科护理可 能相关主题为气道管理、病情观察、护理措施及病情预判;危重症护理能力考试显示,低年资及低学历护士得分相对偏低,而不同 工龄护士得分比较差异无统计学意义(P>0.05);4项主题得分比较,气道管理(59.73%)、病情预判(58.31%)正确率最低,外科 病区与ICU护士得分比较差异有统计学意义(P<0.05)。结论 外科护士危重症护理能力是影响非计划重返ICU的主要原因 之一,气道管理及病情预判应作为病区培训的重点. [ABSTRACT FROM AUTHOR]

This paper explored the characteristics of runoff and sediment yield in purple soil sloping land, and provided a scientific basis for tobacco-growing soil management. [Methods] Long-term positioning observations were carried out on the field outflow plots with different slopes (5°, 10°, 15°, 20°, 25° and 30°), and the characteristics of slope runoff and sediment production with rainfall intensity and slope change were studied. [Results] (1) Through the analysis of rainfall data in the past 10 years, the distribution of rainfall in the study area during the year is extremely uneven. The rainfall from June to September accounts for 80.2% to 92.5% of the annual rainfall; light rain, moderate rain, heavy rain, heavy rain, Heavy rains accounted for 14.6%, 26.7%, 31.5%, 22.5%, and 4.7% of the total rainfall from June to September, and moderate to heavy rains accounted for 80.7% of the total rainfall in the rainy season, which is an important reason for the high intensity of soil erosion; (2) ) The slope runoff coefficient increases with the increase of the maximum 30 min rain intensity. The minimum slope runoff coefficients of 5°, 10°, 15°, 20°, 25° and 30° are 0.033, 0.034, 0.063, 0.092, 0.093, respectively., 0.112, and the maximum are 0.646, 0.666, 0.673, 0.738, 0.742, 0.786, respectively. Under the same rainfall intensity conditions, rainfall can significantly affect the slope runoff coefficient; (3) The sediment yield increases with the increase of the maximum 30 min rain intensity Increase, 5°, 10°, 15°, 20°, 25°, and 30° slope surface sediment yields are 1.7, 1.6, 3.1, 4.8, 2.3, and 1.7 t·km -2 at minimum, and 75.4, 234.7 at maximum, respectively, 440.5, 486.7, 489.5, 477.1 t·km -2, the change of sediment yield with the maximum 30 min rain intensity is affected by vegetation coverage; (4) In light rain (0.14～0.46 mm·min -1 ), medium Rain (0.54～0.88 mm·min -1 ), heavy rain (1.1～1.9 mm·min -1)), the slope runoff coefficient increases with the increase of the slope, and the maximum runoff coefficients are 0.326, 0.565, 0.712, respectively. Under different rain intensities, the sediment yield of the slope varies with the slope. Under light rain and moderate rain, the critical slope of the sediment yield change is 20°, and the maximum sediment yield is 113.8 and 193.5 t·km -2, respectively . The lower critical slope is 25°, the maximum sediment yield is 389.1 t·km -2, and the critical slope changes with the change of rain intensity. [Conclusion] The rainy season is a critical period for the occurrence of regional soil erosion. The slope significantly affects the intensity of soil erosion. Strengthening the water and soil conservation in the rainy season is crucial to the sustainable use of regional soil. [ABSTRACT FROM AUTHOR]

Objective To explore the current situation and future development trend of Tai Chi in the prevention and treatment of osteoporosis, and to provide reference for further research. Methods The literature about Tai Chi in the prevention and treatment of osteoporosis was retrieved from Chinese National Know ledge Infrastructure (CNKI), Wanfang, Chongqing VIP, and PubMed. Methology analysis was conducted from the aspects of publication time, literature type and language, journal distribution, author distribution, publication institution, high-frequency keywords, core outcomes, and other characteristics. Results Totally 210 articles were considered to be eligible for inclusion, and 136 articles were published in the past IO years. This period was hot-period of Tai Chi for osteoporosis and the articles of this period were 64. 76 % of all articles. The number of articles was on the rise, and the literature was mainly clinical research published in Chinese periodical journals. The highest content of the papers were in the Chinese Journal of Osteoporosis and Chinese Journal of Gerontology, respectively. Tai Chi, BMD, the elderly, and women were the most frequently used keywords. BMD, balance ability, and bone metabolism outcomes were commonly used to evaluate the prevention and treatment of osteoporosis. Conclusion In the past 10 years, Tai Chi has been a hot research topic in the prevention and treatment of osteoporosis. The current research is mostly in China and the United States. The research type is mainly clinical research. Modern evidence shows that Tai Chi has a definite effect on the prevention and treatment of osteoporosis. However, there is a lack of standard outcomes, which still needs to be further explored theoretically and supported by higher level of clinical evidence. [ABSTRACT FROM AUTHOR]

Wind tunnel experiments have been conducted for a flying wing aircraft to investigate the effect of plasma actuator arrangement position and control parameters on the lift enhancement of the flying wing aircraft. The AC and nanosecond plasma power have been used separately to study the effect of plasma actuator control parameters on the lift enhancement of the aircraft. The result indicates that the plasma actuator can efficiently increase the maximum lift coefficient and defer the occurrence of the stall with small impacts on drag coefficient of the flying wing aircraft. The actuators arranged parallel to the aircraft leading edge are effective, and they placed at leading edge generate the best lift enhancement. In the experiment condition, the aircraft maximum lift coefficient increases by 39.5%, and the stall angle is postponed by 8 degrees due to the plasma actuator. In nanosecond pluse discharge mode, the input frequency of the plasma actuator has significant impact on the aircraft lift enhancement, while the discharge voltage has a negligible impact. In AC discharge mode, the input duty cycle of plasma actuator has a certain impact on aircraft lift enhancement, and a excessive large one should not be chosen. [ABSTRACT FROM AUTHOR]