Search

Your search keyword '"A. Borghese"' showing total 4,796 results
Start Over Author "A. Borghese"
4,796 results on '"A. Borghese"'

202. From Digital Restitution to Structural Analysis of a Historical Adobe Building: The Escuela José Mariano Méndez in El Salvador

Author

Silvia Santini, Marco Canciani, Vittoria Borghese, Valerio Sabbatini, Claudio Sebastiani, Santini, Silvia, Canciani, Marco, Borghese, Vittoria, Sabbatini, Valerio, and Sebastiani, Claudio

Subjects
laser scanner, FEM, Archeology, historical adobe building, HBIM, Materials Science (miscellaneous), Conservation
Abstract

Nowadays, the research in the fields of conservation and restoration is focusing on recording large amounts of data and information in order to obtain highly accurate surveys that include most details of constructions. Documenting and surveying are fundamental activities in achieving the successful preservation of cultural heritage, but also in implementing efficient strengthening interventions of structures. The applications of methods and techniques that link the disciplines of geometrical surveys and structural analyses are still fragmented, and further research is necessary to fully transfer site information into structural models. In this article, the authors propose a methodology with which to link different restoration fields, with the aim of highlighting the strengths and weaknesses of the interoperability between surveys (carried out through detailed restitution from point clouds), heritage building information modeling (HBIM), and structural analyses to connect three different disciplines. The goal is to find a synthesis model that brings together historical and geometric characteristics, but also physical–mechanical properties, for a structural evaluation through a finite element model (FEM). The case study of the Escuela José Mariano Méndez is analyzed, an extremely damaged historical adobe building in Santa Ana, the second largest city of El Salvador; it is considered fundamental to the national economy, particularly after the “coffee boom” in the late 1800s. The site, located near the historic center, is also known as “Antigua Escuela de Artes y Oficios” and embodies the architectural traditions of the region, being built in adobe and stone. Roma Tre University and the Secretaría de Cultura de la Presidencia (SECULTURA) are partners in this research project to document and restore the historical and cultural value of this site.

Published
2023

203. Carboplatin and paclitaxel plus avelumab compared with carboplatin and paclitaxel in advanced or recurrent endometrial cancer (MITO END-3): a multicentre, open-label, randomised, controlled, phase 2 trial

Author

Sandro Pignata, Giovanni Scambia, Clorinda Schettino, Laura Arenare, Carmela Pisano, Davide Lombardi, Ugo De Giorgi, Claudia Andreetta, Saverio Cinieri, Carmine De Angelis, Domenico Priolo, Claudia Casanova, Marta Rosati, Filippo Greco, Elena Zafarana, Ilaria Schiavetto, Serafina Mammoliti, Sabrina Chiara Cecere, Vanda Salutari, Simona Scalone, Alberto Farolfi, Marilena Di Napoli, Domenica Lorusso, Piera Gargiulo, Daniela Califano, Daniela Russo, Anna Spina, Rossella De Cecio, Paolo Chiodini, Francesco Perrone, Valentina Accinno, Chiara Altavilla, Giovanna Antonelli, Grazia Artioli, Francesco Avola, Bonifacio Barbara, Valentina Barbato, Michele Bartoletti, Simona Bevilacqua, Roberto Bordonaro, Oriana Borghese, Gaetano Buonfanti, Floriana Camarda, Giuliana Canzanella, Vittoria Carbone, Maria Rita Carbone, Giulia Carlo Stella, Chiara Cassani, Fabrizio Castagna, Monica Cattaneo, Margherita Cinefra, Nicoletta Colombo, Serena Corsetti, Monia Dall'Agata, Maria D'Amico, Gennaro Daniele, Elvira De Marino, Giovanni De Matteis, Sabino De Placido, Gabriella Del Bene, Antonia Del Giudice, Francesca Del Monte, Michele Del Sesto, Maddalena Donini, Giuliana Drudi, Gianluca Falcone, Adolfo Favaretto, Giulia Ferrera, Manuela Florio, Valeria Forestieri, Maria Stella Gallo, Ciro Gallo, Francesca Garibaldi, Fabiana Gerevini, Viola Ghizzoni, Maria Olga Giganti, Anna Gimigliano, Elena Giudice, Nicoletta Gnocchi, Adriano Gravina, Stefano Greggi, Maria Laura Iaia, Annalisa Ilardi, Gelsomina Iovine, Gabriella Ippoliti, Giulia Irollo, Ilenia Isidori, Mariateresa Lapresa, Giuseppe Lavenia, Laura Longhitano, Bortot Lucia, Gabriella Luzi, Sara Mariano, Valentina Marino, Giovanna Marrapese, Marilena Martino, Roberta Matocci, Enrica Mazzoni, Daniela Mercuri, Maria Mirto, Giovanna Mollo, Abbondanza Montinaro, Marta Moscatelli, Anna Maria Mosconi, Lucia Musacchio, Nicoletta Nanni, Pamela Natalucci, Milena Sabrina Nicoloso, Michele Orditura, Gabriella Maria Parma, Rodolfo Passalacqua, Michela Pelone, Maria Teresa Perri, Bruno Perrucci, Alessandra Piancastelli, Maria Carmela Piccirillo, Antonio Piccolo, Stefania Rapisardi, Giorgia Ravaglia, Teresa Ribecco, Caterina Ricci, Marianna Roccio, Fiorella Romano, Daniela Sambataro, Alfonso Savio, Ada Sbriglia, Cono Scaffa, Concetta Sergi, Francesca Sgandurra, Roberto Sorio, Stefano Stabile, Gianna Tabaro, Margherita Tambaro, Stefano Tamberi, Angelica Tecchiato, Angela Maria Trujillo, Eleonora Zaccarelli, Pignata, S, Scambia, G, Schettino, C, Arenare, L, Pisano, C, Lombardi, D, De Giorgi, U, Andreetta, C, Cinieri, S, De Angelis, C, Priolo, D, Casanova, C, Rosati, M, Greco, F, Zafarana, E, Schiavetto, I, Mammoliti, S, Cecere, S, Salutari, V, Scalone, S, Farolfi, A, Di Napoli, M, Lorusso, D, Gargiulo, P, Califano, D, Russo, D, Spina, A, De Cecio, R, Chiodini, P, Perrone, F, Accinno, V, Altavilla, C, Antonelli, G, Artioli, G, Avola, F, Barbara, B, Barbato, V, Bartoletti, M, Bevilacqua, S, Bordonaro, R, Borghese, O, Buonfanti, G, Camarda, F, Canzanella, G, Carbone, V, Carbone, M, Carlo Stella, G, Cassani, C, Castagna, F, Cattaneo, M, Cinefra, M, Colombo, N, Corsetti, S, Dall'Agata, M, D'Amico, M, Daniele, G, De Marino, E, De Matteis, G, De Placido, S, Del Bene, G, Del Giudice, A, Del Monte, F, Del Sesto, M, Donini, M, Drudi, G, Falcone, G, Favaretto, A, Ferrera, G, Florio, M, Forestieri, V, Gallo, M, Gallo, C, Garibaldi, F, Gerevini, F, Ghizzoni, V, Giganti, M, Gimigliano, A, Giudice, E, Gnocchi, N, Gravina, A, Greggi, S, Iaia, M, Ilardi, A, Iovine, G, Ippoliti, G, Irollo, G, Isidori, I, Lapresa, M, Lavenia, G, Longhitano, L, Lucia, B, Luzi, G, Mariano, S, Marino, V, Marrapese, G, Martino, M, Matocci, R, Mazzoni, E, Mercuri, D, and Mirto, M

Subjects
Oncology, Carboplatin
Abstract

Background: Adding immunotherapy to first-line chemotherapy might improve outcomes for patients with advanced or recurrent endometrial cancer. We aimed to compare carboplatin and paclitaxel versus avelumab plus carboplatin and paclitaxel as first-line treatment with avelumab given concurrent to chemotherapy and as maintenance after the end of chemotherapy. Methods: MITO END-3 is an open-label, randomised, controlled, phase 2 trial conducted at 31 cancer institutes, hospitals, and universities in Italy. Eligible patients were aged 18 years or older with histologically confirmed advanced (FIGO stage III–IV) or recurrent endometrial cancer, an Eastern Cooperative Oncology Group (ECOG) performance status of 0–1, and no previous systemic anticancer therapy as primary treatment for advanced or metastatic disease. Participants were randomly assigned (1:1) using a computerised minimisation procedure stratified by centre, histology, and stage at study entry, to either receive carboplatin (area under the curve [AUC] 5 mg/mL × min) and paclitaxel (175 mg/m2; standard group) intravenously every 3 weeks for six to eight cycles or avelumab (10 mg/kg intravenously) added to carboplatin and paclitaxel (experimental group) every 3 weeks and then every 2 weeks as a single maintenance treatment after the end of chemotherapy until disease progression or unacceptable toxicity. Patients, treating clinicians, and those assessing radiological examinations were not masked to study treatment. The primary endpoint was investigator-assessed progression-free survival, measured in the intention-to-treat (ITT) population. Patients who received at least one dose of study drug were included in the safety analysis. Experimental group superiority was tested with 80% power and one-tailed α 0·20. This trial is registered with ClinicalTrials.gov (NCT03503786) and EudraCT (2016–004403–31). Findings: From April 9, 2018, to May 13, 2021, 166 women were assessed for eligibility and 39 were excluded. 125 eligible patients were randomly assigned to receive carboplatin and paclitaxel (n=62) or avelumab plus carboplatin and paclitaxel (n=63) and included in the ITT population. The median follow-up was 23·3 months (IQR 13·2–29·6) and was similar between the two groups. 91 progression-free survival events were reported, with 49 events in 62 patients in the standard group and 42 events in 63 patients in the experimental group. The median progression-free survival was 9·9 months (95% CI 6·7–12·1) in the standard group and 9·6 months (7·2–17·7) in the experimental group (HR of progression or death 0·78 [60% CI 0·65–0·93]; one-tailed p=0·085). Serious adverse events were reported more frequently in the experimental group (24 vs seven events in the standard group); neutrophil count decrease was the most frequent grade 3–4 adverse event (19 [31%] of 61 patients in the experimental group vs 26 [43%] of 61 patients in the standard group). Two deaths occurred in the experimental group during treatment (one respiratory failure following severe myositis [possibly related to treatment] and one cardiac arrest [not related to treatment]). Interpretation: Adding avelumab to first-line chemotherapy deserves further testing in patients with advanced or recurrent endometrial cancer, although consideration of mismatch repair status is warranted.

Published
2023

206. Assessment of the Sabellaria alveolata reefs’ structural features along the Southern coast of Sicily (Strait of Sicily, Mediterranean Sea)

Author

JACOPO BORGHESE, DANIELE ARDUINI, EUGENIA SCHIMMENTI, DAVIDE IACIOFANO, BARBARA MIKAC, FABIO BADALAMENTI, ADRIANA GIANGRANDE, MARIA FLAVIA GRAVINA, LUIGI MUSCO, SABRINA LO BRUTTO, BORGHESE, JACOPO, ARDUINI, DANIELE, SCHIMMENTI, EUGENIA, IACIOFANO, DAVIDE, MIKAC, BARBARA, BADALAMENTI, FABIO, GIANGRANDE, ADRIANA, GRAVINA, MARIA FLAVIA, MUSCO, LUIGI, LO BRUTTO, SABRINA, Borghese J., Arduini D., Schimmenti E., Iaciofano D., Mikac B., Badalamenti F., Giangrande A., Gravina M.F., Musco L., and Lo Brutto S.

Subjects
engineer species, habitat heterogeneity, Environmental Engineering, Settore BIO/07, Settore BIO/05 - Zoologia, Polychaeta, Aquatic Science, Oceanography, Sabellaria, marine conservation, biogenic reefs, Mediterranean Sea, biogenic reef, engineer specie, habitat-former species, Ecology, Evolution, Behavior and Systematics, biodiversity
Abstract

The honeycomb worm Sabellaria alveolata is a gregarious tube-dwelling polychaete that builds remarkable biogenic reefs in marine coastal waters. Sabellaria alveolata reefs are considered valuable marine habitats requiring protection measures for their conservation, as they play a key role in the functioning of coastal ecosystems. Sabellarid reefs are extensively developed along the Atlantic coasts of Europe and reported for the Mediterranean Sea and the Italian coasts, where large reefs have been recorded in several localities. Fragmentary information is available on their health status, Sabellaria reefs thus being listed as “Data Deficient” in the Red List of Marine Habitats. To fill this knowledge gap, this study focused on the analysis of the structure of three reefs found along the southern coast of Sicily. In particular, we aimed to assess their phases with respect to the natural cycle that characterizes the sabellarid reefs. Reef features were analyzed both on the macroscale, based on the bioconstruction size (diameter and thickness) and degree of fragmentation, and on the microscale, based on the measurement of worm density, opercular length and sand porch presence. This study reveals relevant differences among reefs of the studied locations. These differences we attributeto the temporal shift linked to the natural reef phases, albeit further analyses are needed to understand the possible effect of natural and anthropogenic sources of variation on the Southern Sicilian reefs. In conclusion, Sabellaria reefs are a unique and persistent habitat along the Sicilian coast requiring proper management and conservation measures.

Published
2022

207. Correction to: Integrating Social Assistive Robots, IoT, Virtual Communities and Smart Objects to Assist at-Home Independently Living Elders: the MoveCare Project

Author

Luperto, Matteo, Monroy, Javier, Renoux, Jennifer, Lunardini, Francesca, Basilico, Nicola, Bulgheroni, Maria, Cangelosi, Angelo, Cesari, Matteo, Cid, Manuel, Ianes, Aladar, Gonzalez-Jimenez, Javier, Kounoudes, Anastasis, Mari, David, Prisacariu, Victor, Savanovic, Arso, Ferrante, Simona, and Borghese, N. Alberto

Published
2022
Full Text
View/download PDF

210. Power-law cosmologies in minimal and maximal gauged supergravity

Author

Blåbäck, J., Borghese, A., and Haque, S. S.

Subjects
High Energy Physics - Theory
Abstract

In this paper we search for accelerating power-law solutions and ekpyrotic solutions within minimal and maximal four dimensional supergravity theories. We focus on the STU model for N=1 and on the new CSO(p,q,r) theories, which were recently obtained exploiting electromagnetic duality, for N=8. In the minimal case we find some new ekpyrotic solutions, while in the maximal case we find some new generic power-law solutions. We do not find any new accelerating solutions for these models., Comment: 25 pages

Published
2013

211. Triality, Periodicity and Stability of SO(8) Gauged Supergravity

Author

Borghese, Andrea, Guarino, Adolfo, and Roest, Diederik

Subjects
High Energy Physics - Theory
Abstract

While electromagnetic duality is a symmetry of many supergravity theories, this is not the case for the N=8 gauged theory. It was recently shown that this rotation leads to a one-parameter family of SO(8) supergravities. It is an open question what the period of this parameter is. This issue is investigated in the SO(4) invariant sectors of the theory. We classify such critical points and find a novel branch of non-supersymmetric and unstable solutions, whose embedding is related via triality to the two known ones. Secondly, we show that the three branches of solutions lead to a Pi/4 periodicity of the vacuum structure. The general interrelations between triality and periodicity are discussed. Finally, we comment on the connection to other gauge groups as well as the possibility to achieve (non-)perturbative stability around AdS/Mkw/dS transitions., Comment: 7 pages, 4 figures. v2: Published version

Published
2013
Full Text
View/download PDF

212. The many surprises of maximal supergravity

Author

Borghese, Andrea, Guarino, Adolfo, and Roest, Diederik

Subjects
High Energy Physics - Theory
Abstract

We describe recent developments regarding gauged N=8 supergravity in D=4. Using the embedding tensor formulation we show how to classify all the extrema of this theory with a G2 residual gauge symmetry. Our classification contains all the vacua of the recently discovered family of SO(8) gauged maximal supergravities., Comment: Contribution to the proceedings of Barcelona Postgrad Encounters on Fundamental Physics

Published
2013

216. Following the digestion of milk proteins from mother to baby.

Author

Holton, Thérèse A, Vijayakumar, Vaishnavi, Dallas, David C, Guerrero, Andrés, Borghese, Robyn A, Lebrilla, Carlito B, German, J Bruce, Barile, Daniela, Underwood, Mark A, Shields, Denis C, and Khaldi, Nora

Subjects
Stomach, Gastric Mucosa, Milk, Human, Humans, Endopeptidases, Cathepsin D, Pepsin A, Chymotrypsin, Pancreatic Elastase, Trypsin, Peptides, Milk Proteins, Intubation, Gastrointestinal, Mothers, Proteomics, Digestion, Infant, Newborn, Female, Mass Spectrometry, Fibrinolysin, Proteolysis, digestive enzymes, enzyme activity, human milk, indigenous enzymes, infant digestion, milk enzymes, proteolytic enzymes, Nutrition, Digestive Diseases, Pediatric, Clinical Research, 1.1 Normal biological development and functioning, Underpinning research, Chemical Sciences, Biological Sciences, Biochemistry & Molecular Biology
Abstract

Little is known about the digestive process in infants. In particular, the chronological activity of enzymes across the course of digestion in the infant remains largely unknown. To create a temporal picture of how milk proteins are digested, enzyme activity was compared between intact human milk samples from three mothers and the gastric samples from each of their 4-12 day postpartum infants, 2 h after breast milk ingestion. The activities of 7 distinct enzymes are predicted in the infant stomach based on their observed cleavage pattern in peptidomics data. We found that the same patterns of cleavage were evident in both intact human milk and gastric milk samples, demonstrating that the enzyme activities that begin in milk persist in the infant stomach. However, the extent of enzyme activity is found to vary greatly between the intact milk and gastric samples. Overall, we observe that milk-specific proteins are cleaved at higher levels in the stomach compared to human milk. Notably, the enzymes we predict here only explain 78% of the cleavages uniquely observed in the gastric samples, highlighting that further investigation of the specific enzyme activities associated with digestion in infants is warranted.

Published
2014

220. The SU(3)-invariant sector of new maximal supergravity

Author

Borghese, A., Dibitetto, G., Guarino, A., Roest, D., and Varela, O.

Subjects
High Energy Physics - Theory
Abstract

We investigate the SU(3)-invariant sector of the one-parameter family of SO(8) gauged maximal supergravity that has been recently proposed. To this end, we construct the N=2 truncation of this theory and analyse its full vacuum structure. The number of critical point is doubled and includes new N=0 and N=1 branches. We numerically exhibit the parameter dependence of the location and cosmological constant of all extrema. Moreover, we provide their analytic expressions for cases of special interest. Connections with three-dimensional RG-flows are pointed out. Finally, while the mass spectra are found to be parameter independent in most cases, we show that the novel non-supersymmetric branch with SU(3) invariance provides the first counterexample to this., Comment: 47 pages, 8 figures and 3 tables. v3: references added, published version

Published
2012
Full Text
View/download PDF

221. All G_2 invariant critical points of maximal supergravity

Author

Borghese, Andrea, Guarino, Adolfo, and Roest, Diederik

Subjects
High Energy Physics - Theory
Abstract

We perform an exhaustive classification of G_2 invariant extrema of the most general gauged N=8 supergravity in four dimensions. They comprise four branches of Anti-de Sitter solutions labelled by a single parameter. Interestingly, while the gauge groups vary with the parameters, the mass spectra are invariant. One of these is a new non-supersymmetric yet stable point. Our analysis includes the recently proposed family of SO(8) gauged supergravities and more., Comment: 5 pages. v2: extended discussion of vector masses and gauge groups and refs added

Published
2012
Full Text
View/download PDF

222. Superconductors for superstrings on AdS_5 x T^{1,1}

Author

Aprile, Francesco, Borghese, Andrea, Dector, Aldo, Roest, Diederik, and Russo, Jorge G.

Subjects
High Energy Physics - Theory
Abstract

We construct a one-parameter family of five-dimensional N=2 supergravity Lagrangians with an SU(2,1) / U(2) hypermultiplet. For certain values of the parameter, these are argued to describe the dynamics of scalar modes of superstrings on AdS_5 x T^{1,1}, and therefore to be dual to specific chiral primary operators of Klebanov-Witten superconformal field theory. We demonstrate that, below a critical temperature, the thermodynamics is dominated by charged black holes with hair for the scalars that are dual to the operator of lowest conformal dimension 3/2. The system thus enters into a superconducting phase where condenses., Comment: 5 pages, 5 figures

Published
2012
Full Text
View/download PDF

223. A geometric bound on F-term inflation

Author

Borghese, Andrea, Roest, Diederik, and Zavala, Ivonne

Subjects
High Energy Physics - Theory, Astrophysics - Cosmology and Nongalactic Astrophysics, High Energy Physics - Phenomenology
Abstract

We discuss a general bound on the possibility to realise inflation in any minimal supergravity with F-terms. The derivation crucially depends on the sGoldstini, the scalar field directions that are singled out by spontaneous supersymmetry breaking. The resulting bound involves both slow-roll parameters and the geometry of the K\"ahler manifold of the chiral scalars. We analyse the inflationary implications of this bound, and in particular discuss to what extent the requirements of single field and slow-roll can both be met in F-term inflation., Comment: 14 pages, improved analysis, references added, matches published version

Published
2012
Full Text
View/download PDF

224. Non-Linear Gate Stack Effect on the Short Circuit Performance of a 1.2-kV SiC MOSFET

Author

Boccarossa, Marco, Maresca, Luca, Borghese, Alessandro, Riccio, Michele, Breglio, Giovanni, Irace, Andrea, and Salvatore, Giovanni Antonio

Abstract

In this paper, the effect of a non-linear dielectric gate stack on the short-circuit performance of a 1.2 kV SiC MOSFET was analyzed through TCAD simulations. Starting from the TCAD model of a commercial 1.2 kV, its standard gate oxide was replaced with a stack formed by oxide and a non‑linear dielectric, characterized by a temperature dependent permittivity. This variation on temperature can be exploited to reduce the current conducted during short-circuit events, lowering the temperature reached through the device by about 30%, without affecting its static and dynamic performance.

Published
2024
Full Text
View/download PDF

225. Analysis of Electrothermal Imbalance of Hard-Switched Parallel SiC MOSFETs through Infrared Thermography

Author

Borghese, Alessandro, Angora, Stefano, Boccarossa, Marco, Riccio, Michele, Maresca, Luca, Marrazzo, Vincenzo Romano, Breglio, Giovanni, and Irace, Andrea

Abstract

This paper provides an experimental investigation through infrared thermography of the steady-state temperature imbalance arising in parallel SiC MOSFETs. A switched-mode boost power converter based on two arrays of 4 parallel 1.2 kV MOSFETs is selected as a case-study. The analysis aims at proving that a proper device arrangement can minimize the thermal imbalance in the absence of circuit layout optimization.

Published
2024
Full Text
View/download PDF

226. SiC GAA MOSFET Concept for High Power Electronics Performance Evaluation through Advanced TCAD Simulations

Author

Maresca, Luca, Terracciano, Vincenzo, Borghese, Alessandro, Boccarossa, Marco, Riccio, Michele, Breglio, Giovanni, Mihaila, Andrei, Romano, Gianpaolo, Wirths, Stephan, Knoll, Lars, and Irace, Andrea

Abstract

In this work a groundbreaking SiC power MOSFET based on innovative vertical Gate All Around (GAA) concept is presented. Extensive TCAD simulations are performed to analyze the performance in forward as well as in reverse conditions for this new device concept. The proposed design has a target rating voltage of 1200V, suitable for e-mobility applications.

Published
2024
Full Text
View/download PDF

227. A Geometry-Scalable Physically-Based SPICE Compact Model for SiC MPS Diodes Including the Snapback Mechanism

Author

Terracciano, Vincenzo, Borghese, Alessandro, Boccarossa, Marco, d'Alessandro, Vincenzo, and Irace, Andrea

Abstract

In this paper, a simple compact model for the static behavior of SiC MPS diodes is developed in the form of a SPICE-compatible subcircuit. The model is suited to describe the undesired snapback mechanism likely to occur in unoptimized high-voltage MPS structures with narrow width of the PiN portion and/or very thick drift layer; in particular, the model accounts for the snapback mechanism both as the cell extension varies and as individual portions of Schottky and PiN vary. Sentaurus TCAD simulations of a 10-kV MPS diode are used as a reference for the calibration of the model parameters and accuracy verification.

Published
2024
Full Text
View/download PDF

228. Minimal Stability in Maximal Supergravity

Author

Borghese, Andrea, Linares, Roman, and Roest, Diederik

Subjects
High Energy Physics - Theory
Abstract

Recently, it has been shown that maximal supergravity allows for non-supersymmetric AdS critical points that are perturbatively stable. We investigate this phenomenon of stability without supersymmetry from the sGoldstino point of view. In particular, we calculate the projection of the mass matrix onto the sGoldstino directions, and derive the necessary conditions for stability. Indeed we find a narrow window allowing for stable SUSY breaking points. As a by-product of our analysis, we find that it seems impossible to perturb supersymmetric critical points into non-supersymmetric ones: there is a minimal amount of SUSY breaking in maximal supergravity., Comment: 27 pages, 1 figure. v2: two typos corrected, published version

Published
2011
Full Text
View/download PDF

229. Metastable supersymmetry breaking in extended supergravity

Author

Borghese, Andrea and Roest, Diederik

Subjects
High Energy Physics - Theory
Abstract

We consider the stability of non-supersymmetric critical points of general N=4 supergravities. A powerful method to analyse this issue based on the sGoldstino direction has been developed for minimal supergravity. We adapt this to the present case, and address the conceptually new features arising for extended supersymmetry. As an application, we investigate the stability when supersymmetry breaking proceeds via either the gravity or the matter sector. Finally, we outline the N=8 case., Comment: 27 pages. v2 correct replacement: typos corrected and clarifications added on gauge invariance and dependence on SUSY mass terms

Published
2010
Full Text
View/download PDF

230. Brownian Motion of Graphene

Author

Marago, O. M., Bonaccorso, F., Saija, R., Privitera, G., Gucciardi, P. G., Iati, M. A., Calogero, G., Jones, P. H., Borghese, F., Denti, P., Nicolosi, V., and Ferrari, A. C.

Subjects
Condensed Matter - Materials Science, Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

We study the Brownian motion (BM) of optically trapped graphene flakes. These orient orthogonal to the light polarization, due to the optical constants anisotropy. We explain the flake dynamics, measure force and torque constants and derive a full electromagnetic theory of optical trapping. The understanding of two dimensional BM paves the way to light-controlled manipulation and all-optical sorting of biological membranes and anisotropic macromolecules.

Published
2010

231. Nanopolaritons: Vacuum Rabi splitting with a single quantum dot in the center of a dimer nanoantenna

Author

Savasta, S., Saja, R., Ridolfo, A., Di Stefano, O., Denti, P., and Borghese, F.

Subjects
Quantum Physics
Abstract

The demonstration of enhanced spontaneous emission of nanoscaled optical emitters near metallic nanoparticles and the recent realization of a nanolaser based on surface plasmon amplification by stimulated emission of radiation (spaser) encourage the search for strong coupling regime at the nanoscale. Here we propose the concept of nanopolaritons. We demonstrate with accurate scattering calculations that the strong coupling regime of a single quantum emitter (a semiconductor quantum dot) placed in the gap between two metallic nanoparticles can be achieved. The largest dimension of the investigated system is only 36 nm. Nanopolaritons will advance our fundamental understanding of surface plasmon enhanced optical interactions and could be used as ultra-compact elements in quantum-information technology., Comment: 13 pages, 2 figures.

Published
2010

232. Rotational dynamics of optically trapped polymeric nanofibers

Author

Neves, Antonio Alvaro Ranha, Camposeo, Andrea, Pagliara, Stefano, Saija, Rosalba, Borghese, Ferdinando, Denti, Paolo, Iati, Maria Antonia, Cingolani, Roberto, Marago, Onofrio M., and Pisignano, Dario

Subjects
Physics - Optics
Abstract

The optical trapping of polymeric nanofibers and the characterization of the rotational dynamics are reported. A strategy to apply a torque to a polymer nanofiber, by tilting the trapped fibers using a symmetrical linear polarized Gaussian beam is demonstrated. Rotation frequencies up to 10 Hz are measured, depending on the trapping power, the fiber length and the tilt angle. A comparison of the experimental rotation frequencies in the different trapping configurations with calculations based on optical trapping and rotation of linear nanostructures through a T-Matrix formalism, accurately reproduce the measured data, providing a comprehensive description of the trapping and rotation dynamics., Comment: (21 pages, 5 figures)

Published
2009
Full Text
View/download PDF

233. A Peptidomic Analysis of Human Milk Digestion in the Infant Stomach Reveals Protein-Specific Degradation Patterns

Author

Dallas, David C, Guerrero, Andrés, Khaldi, Nora, Borghese, Robyn, Bhandari, Aashish, Underwood, Mark A, Lebrilla, Carlito B, German, J Bruce, and Barile, Daniela

Subjects
Biomedical and Clinical Sciences, Nutrition and Dietetics, Pediatric, Digestive Diseases, Nutrition, Bile Acids and Salts, Breast Feeding, Caseins, Digestion, Female, Gastric Mucosa, Humans, Infant, Newborn, Intestinal Mucosa, Lactalbumin, Lactation, Lactoferrin, Male, Milk Proteins, Milk, Human, Peptides, Proteolysis, Serum Albumin, Xanthine Dehydrogenase, Animal Production, Food Sciences, Nutrition & Dietetics, Animal production, Food sciences, Nutrition and dietetics
Abstract

In vitro digestion of isolated milk proteins results in milk peptides with a variety of actions. However, it remains unclear to what degree protein degradation occurs in vivo in the infant stomach and whether peptides previously annotated for bioactivity are released. This study combined nanospray LC separation with time-of-flight mass spectrometry, comprehensive structural libraries, and informatics to analyze milk from 3 human mothers and the gastric aspirates from their 4- to 12-d-old postpartum infants. Milk from the mothers contained almost 200 distinct peptides, demonstrating enzymatic degradation of milk proteins beginning either during lactation or between milk collection and feeding. In the gastric samples, 649 milk peptides were identified, demonstrating that digestion continues in the infant stomach. Most peptides in both the intact milk and gastric samples were derived from β-casein. The numbers of peptides from β-casein, lactoferrin, α-lactalbumin, lactadherin, κ-casein, serum albumin, bile salt-associated lipase, and xanthine dehydrogenase/oxidase were significantly higher in the gastric samples than in the milk samples (P < 0.05). A total of 603 peptides differed significantly in abundance between milk and gastric samples (P < 0.05). Most of the identified peptides have previously identified biologic activity. Gastric proteolysis occurs in the term infant in the first 2 wk of life, releasing biologically active milk peptides with immunomodulatory and antibacterial properties of clinical relevance to the proximal intestinal tract. Data are available via ProteomeXchange (identifier PXD000688).

Published
2014

234. Impact of Pregnancy on Breast Cancer Features and Prognosis.

Author

Bounous, Valentina E., Minella, Carola, Fuso, Luca, Actis, Silvia, Petroni, Greta, Sgrò, Luca G., Borghese, Martina, Tomasi Cont, Nicoletta, Ponzone, Riccardo, and Ferrero, Annamaria

Subjects
BREAST cancer prognosis, PREGNANCY, HORMONE receptors, NODAL analysis, PROGNOSIS
Abstract

Background: pregnancy-associated breast cancer (PABC) affects one in 3000 pregnancies, often presenting with aggressive features. Methods: We retrospectively evaluated a cohort of 282 young BC patients (≤45 years old) treated between 1995 and 2019, dividing them into three groups: nulliparous women, women with PABC (diagnosed within 2 years since last pregnancy) and women with BC diagnosed > 2 years since last pregnancy. This last group was further stratified according to the time between pregnancy and BC. The analysis encompassed histological factors (tumor size, histotype, grading, nodal involvement, multifocality, lympho-vascular invasion, hormone receptor expression, Ki-67 index, and HER2 expression), type of surgery and recurrence. Results: Age at diagnosis was younger in nulliparous than in parous women (p < 0.001). No significant differences were noticed regarding histological characteristics and recurrences. At univariate analysis, nodal involvement (OR = 2.4; p < 0.0001), high tumor grade (OR = 2.6; p = 0.01), and lympho-vascular invasion (OR = 2.3; p < 0.05), but not pregnancy (OR = 0.8; p = 0.30), influenced DFS negatively. Multivariate analysis confirmed nodal involvement as the only negative independent prognostic factor for a worse DFS (OR = 2.4; p = 0.0001). Conclusions: in our experience, pregnancy is not an independent adverse prognostic factor for BC DFS. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

241. Comparison of perioperative surgical outcomes between contained and free manual vaginal morcellation of large uteruses following total laparoscopic hysterectomy

Author

Raimondo, Diego, primary, Raffone, Antonio, additional, Franceschini, Camilla, additional, Virgilio, Agnese, additional, Palermo, Roberto, additional, Borghese, Giulia, additional, Maletta, Manuela, additional, Borgia, Alessandra, additional, Neola, Daniele, additional, Travaglino, Antonio, additional, Lenzi, Jacopo, additional, Guida, Maurizio, additional, and Seracchioli, Renato, additional

Published
2023
Full Text
View/download PDF

242. Cohort profile update: The Canadian Maternal–Infant Research on Environmental Chemicals Child Development study (MIREC‐CD PLUS)

Author

Fisher, Mandy, primary, Muckle, Gina, additional, Lanphear, Bruce, additional, Arbuckle, Tye E., additional, Braun, Joseph M., additional, Zidek, Angelika, additional, Vélez, Maria P., additional, Lupien, Nicole, additional, Bastien, Stephanie, additional, Ashley‐Martin, Jillian, additional, Oulhote, Youssef, additional, Borghese, Michael M., additional, Walker, Mark, additional, Asztalos, Elizabeth, additional, Bouchard, Maryse F., additional, Booij, Linda, additional, Palmert, Mark R., additional, Morrison, Katherine M., additional, Cummings, Elizabeth A., additional, Khatchadourian, Karine, additional, Panagiotopoulos, Constadina, additional, Glendon, Gord, additional, Shutt, Robin, additional, Abdul‐Fatah, Ammanie, additional, Seal, Kelsey, additional, and Fraser, William D., additional

Published
2023
Full Text
View/download PDF

245. Observations of the Crab Nebula and Pulsar with the Large-sized Telescope Prototype of the Cherenkov Telescope Array

Author

Abe, H., primary, Abe, K., additional, Abe, S., additional, Aguasca-Cabot, A., additional, Agudo, I., additional, Crespo, N. Alvarez, additional, Antonelli, L. A., additional, Aramo, C., additional, Arbet-Engels, A., additional, Arcaro, C., additional, Artero, M., additional, Asano, K., additional, Aubert, P., additional, Baktash, A., additional, Bamba, A., additional, Larriva, A. Baquero, additional, Baroncelli, L., additional, de Almeida, U. Barres, additional, Barrio, J. A., additional, Batkovic, I., additional, Baxter, J., additional, González, J. Becerra, additional, Bernardini, E., additional, Bernardos, M. I., additional, Medrano, J. Bernete, additional, Berti, A., additional, Bhattacharjee, P., additional, Biederbeck, N., additional, Bigongiari, C., additional, Bissaldi, E., additional, Blanch, O., additional, Bonnoli, G., additional, Bordas, P., additional, Borghese, A., additional, Bulgarelli, A., additional, Burelli, I., additional, Buscemi, M., additional, Cardillo, M., additional, Caroff, S., additional, Carosi, A., additional, Cassol, F., additional, Cauz, D., additional, Ceribella, G., additional, Chai, Y., additional, Cheng, K., additional, Chiavassa, A., additional, Chikawa, M., additional, Chytka, L., additional, Cifuentes, A., additional, Contreras, J. L., additional, Cortina, J., additional, Costantini, H., additional, D’Amico, G., additional, Dalchenko, M., additional, De Angelis, A., additional, de Bony de Lavergne, M., additional, De Lotto, B., additional, de Menezes, R., additional, Deleglise, G., additional, Delgado, C., additional, Delgado Mengual, J., additional, Volpe, D. della, additional, Dellaiera, M., additional, Depaoli, D., additional, Di Piano, A., additional, Di Pierro, F., additional, Di Tria, R., additional, Di Venere, L., additional, Díaz, C., additional, Dominik, R. M., additional, Prester, D. Dominis, additional, Donini, A., additional, Dorner, D., additional, Doro, M., additional, Elsässer, D., additional, Emery, G., additional, Escudero, J., additional, Ramazani, V. Fallah, additional, Ferrara, G., additional, Ferrarotto, F., additional, Fiasson, A., additional, Coromina, L. Freixas, additional, Fröse, S., additional, Fukami, S., additional, Fukazawa, Y., additional, Garcia, E., additional, Garcia López, R., additional, Gasbarra, C., additional, Gasparrini, D., additional, Geyer, F., additional, Paiva, J. Giesbrecht, additional, Giglietto, N., additional, Giordano, F., additional, Giro, E., additional, Gliwny, P., additional, Godinovic, N., additional, Grau, R., additional, Green, D., additional, Green, J., additional, Gunji, S., additional, Hackfeld, J., additional, Hadasch, D., additional, Hahn, A., additional, Hashiyama, K., additional, Hassan, T., additional, Hayashi, K., additional, Heckmann, L., additional, Heller, M., additional, Llorente, J. Herrera, additional, Hirotani, K., additional, Hoffmann, D., additional, Horns, D., additional, Houles, J., additional, Hrabovsky, M., additional, Hrupec, D., additional, Hui, D., additional, Hütten, M., additional, Iarlori, M., additional, Imazawa, R., additional, Inada, T., additional, Inome, Y., additional, Ioka, K., additional, Iori, M., additional, Ishio, K., additional, Iwamura, Y., additional, Jacquemont, M., additional, Martinez, I. Jimenez, additional, Jurysek, J., additional, Kagaya, M., additional, Karas, V., additional, Katagiri, H., additional, Kataoka, J., additional, Kerszberg, D., additional, Kobayashi, Y., additional, Kong, A., additional, Kubo, H., additional, Kushida, J., additional, Lainez, M., additional, Lamanna, G., additional, Lamastra, A., additional, Le Flour, T., additional, Linhoff, M., additional, Longo, F., additional, López-Coto, R., additional, López-Moya, M., additional, López-Oramas, A., additional, Loporchio, S., additional, Lorini, A., additional, Luque-Escamilla, P. L., additional, Majumdar, P., additional, Makariev, M., additional, Mandat, D., additional, Manganaro, M., additional, Manicò, G., additional, Mannheim, K., additional, Mariotti, M., additional, Marquez, P., additional, Marsella, G., additional, Martí, J., additional, Martinez, O., additional, Martínez, G., additional, Martínez, M., additional, Marusevec, P., additional, Mas-Aguilar, A., additional, Maurin, G., additional, Mazin, D., additional, Guillen, E. Mestre, additional, Micanovic, S., additional, Miceli, D., additional, Miener, T., additional, Miranda, J. M., additional, Mirzoyan, R., additional, Mizuno, T., additional, Gonzalez, M. Molero, additional, Molina, E., additional, Montaruli, T., additional, Monteiro, I., additional, Moralejo, A., additional, Morcuende, D., additional, Morselli, A., additional, Mrakovcic, K., additional, Murase, K., additional, Nagai, A., additional, Nagataki, S., additional, Nakamori, T., additional, Nickel, L., additional, Nievas, M., additional, Nishijima, K., additional, Noda, K., additional, Nosek, D., additional, Nozaki, S., additional, Ohishi, M., additional, Ohtani, Y., additional, Oka, T., additional, Okazaki, N., additional, Okumura, A., additional, Orito, R., additional, Otero-Santos, J., additional, Palatiello, M., additional, Paneque, D., additional, Pantaleo, F. R., additional, Paoletti, R., additional, Paredes, J. M., additional, Pech, M., additional, Pecimotika, M., additional, Peresano, M., additional, Pérez, A., additional, Pietropaolo, E., additional, Pirola, G., additional, Plard, C., additional, Podobnik, F., additional, Poireau, V., additional, Polo, M., additional, Pons, E., additional, Prandini, E., additional, Prast, J., additional, Principe, G., additional, Priyadarshi, C., additional, Prouza, M., additional, Rando, R., additional, Rhode, W., additional, Ribó, M., additional, Rizi, V., additional, Fernandez, G. Rodriguez, additional, Ruiz, J. E., additional, Saito, T., additional, Sakurai, S., additional, Sanchez, D. A., additional, Šarić, T., additional, Sato, Y., additional, Saturni, F. G., additional, Schleicher, B., additional, Schmuckermaier, F., additional, Schubert, J. L., additional, Schussler, F., additional, Schweizer, T., additional, Arroyo, M. Seglar, additional, Silvia, R., additional, Sitarek, J., additional, Sliusar, V., additional, Spolon, A., additional, Strišković, J., additional, Strzys, M., additional, Suda, Y., additional, Sunada, Y., additional, Tajima, H., additional, Takahashi, H., additional, Takahashi, M., additional, Takata, J., additional, Takeishi, R., additional, Tam, P. H. T., additional, Tanaka, S. J., additional, Tateishi, D., additional, Tejedor, L. A., additional, Temnikov, P., additional, Terada, Y., additional, Terauchi, K., additional, Terzic, T., additional, Teshima, M., additional, Tluczykont, M., additional, Tokanai, F., additional, Torres, D. F., additional, Travnicek, P., additional, Truzzi, S., additional, Tutone, A., additional, Uhlrich, G., additional, Vacula, M., additional, Vallania, P., additional, van Scherpenberg, J., additional, Acosta, M. Vázquez, additional, Verguilov, V., additional, Viale, I., additional, Vigliano, A., additional, Vigorito, C. F., additional, Vitale, V., additional, Voutsinas, G., additional, Vovk, I., additional, Vuillaume, T., additional, Walter, R., additional, Will, M., additional, Yamamoto, T., additional, Yamazaki, R., additional, Yoshida, T., additional, Yoshikoshi, T., additional, Zywucka, N., additional, Bernlöhr, K., additional, Gueta, O., additional, Kosack, K., additional, Maier, G., additional, and Watson, J., additional

Published
2023
Full Text
View/download PDF

248. Personal care product use and perfluoroalkyl substances in pregnant and postpartum women and adolescents in the United States and Canada

Author

Hall, Amber M, primary, Martin, Jillian Ashley, additional, Liang, Chun Lei, additional, Papandonatos, George, additional, Arbuckle, Tye E, additional, Borghese, Michael M, additional, Buckley, Jessie P, additional, Cecil, Kim M, additional, Chen, Aimin, additional, Fisher, Mandy, additional, Lanphear, Bruce P, additional, Palaniyandi, Jana, additional, Rawn, Dorothea Fk, additional, Yolton, Kimberly, additional, and Braun, Joseph, additional

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results