101. A model of two-stage newborn hearing screening with automated auditory brainstem response.
- Author
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Iwasaki S, Hayashi Y, Seki A, Nagura M, Hashimoto Y, Oshima G, and Hoshino T
- Subjects
- Audiometry, Auditory Threshold physiology, Conditioning, Classical physiology, False Positive Reactions, Hearing Loss congenital, Hearing Loss physiopathology, Humans, Infant, Infant, Newborn, Japan, Orientation physiology, Evoked Potentials, Auditory, Brain Stem physiology, Hearing Loss diagnosis, Neonatal Screening methods
- Abstract
Our purpose was to evaluate a two-stage newborn hearing screening program using automated auditory brainstem response (AABR) before discharge and to describe our follow-up program. This study used 4085 infants born in the Seirei-Hamamatsu and Mikatahara General Hospitals during a 2-year period. The initial screening test was performed 2 or 3 days after birth at an intensity of 35 dBnHL. For the infants who were referred from this test, the re-screening test was performed 5 or 6 days after birth. Diagnostic work-up with auditory brainstem response (ABR), otoacoustic emissions (OAE), and a conditioned orientation reflex audiometry (COR) test were performed by the age of 3-6 months. The referral rate was 1.20% (49/4085 infants) in the first test and 0.71% (29/4085 infants) in the two-stage screening. The two-stage screening procedure was able to reduce the false-positive rate from 0.83 to 0.34%. The incidence of bilateral and unilateral congenital hearing loss diagnosed by ABR was 8/4085 (0.20%) infants and 7/4085 (0.17%) infants, respectively. One infant with congenital cytomegalovirus infection, who passed the two-stage AABR tests, was diagnosed with hearing loss 1 month after birth, using ABR. The two-stage measurement of AABR is effective and time efficient due to significant decreases in the referral rate and the false-positive rate.
- Published
- 2003
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