40 results on '"Frank Narjes"'
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2. Emerging modes-of-action in drug discovery
3. Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2
4. Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor RORγ
5. Identification of indole inhibitors of human hematopoietic prostaglandin D2 synthase (hH-PGDS)
6. HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase
7. Development of a Scalable Chiral Synthesis of MK-3281, an Inhibitor of the Hepatitis C Virus NS5B Polymerase
8. 2-(3-Thienyl)-5,6-dihydroxypyrimidine-4-carboxylic acids as inhibitors of HCV NS5B RdRp
9. Optimization of Thienopyrrole-Based Finger-Loop Inhibitors of the Hepatitis C Virus NS5B Polymerase
10. Cyclic phosphoramidates as prodrugs of 2′-C-methylcytidine
11. Synthesis of Indolo[2,1-a][2]benzazepine and Indolo[2,1-a][2]-benzazocine
12. Improved modular synthesis of thieno[3,2-b]pyrroles and thieno[2,3-b]pyrroles
13. Synthesis and evaluation of novel phosphoramidate prodrugs of 2′-methyl cytidine as inhibitors of hepatitis c virus NS5B polymerase
14. Synthesis and SAR of piperazinyl-N-phenylbenzamides as inhibitors of hepatitis C virus RNA replication in cell culture
15. Inhibitors of the hepatitis C virus RNA-dependent RNA polymerase
16. A designed P1 cysteine mimetic for covalent and non-covalent inhibitors of HCV NS3 protease
17. Back Cover: Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor RORγ (ChemMedChem 2/2016)
18. Application of intramolecular Heck reactions to the preparation of steroid and terpene intermediates having cis A-B ring fusions. Model studies for the total synthesis of complex cardenolides
19. Synthesis of (+)-Artemeseole
20. Synthesis of vinylcyclopropanes by intramolecular epoxide ring opening. Application for an enantioselective synthesis of dictyopterene A
21. ChemInform Abstract: Synthesis of Vinylcyclopropanes from Epoxides
22. ChemInform Abstract: Synthesis of rac-Norartemeseol
23. ChemInform Abstract: Synthesis of Ethynylcyclopropanes from Epoxides
24. ChemInform Abstract: 3-Methoxy-1-phenylthio-1-propene as d1/d3 Synthon: Application for an Asymmetric Synthesis of (S)-(+)-Parasorbic Acid
25. Synthese vonrac-Norartemeseol
26. Synthesis of vinylcyclopropanes from epoxides
27. Discovery of pentacyclic compounds as potent inhibitors of hepatitis C virus NS5B RNA polymerase
28. Tetracyclic indole inhibitors of hepatitis C virus NS5B-polymerase
29. Development of carboxylic acid replacements in indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase
30. Suzuki Coupling at the 2-Position of Densely Functionalized Pyrimidones
31. Identification of thieno[3,2-b]pyrroles as allosteric inhibitors of hepatitis C virus NS5B polymerase
32. Active Site Inhibitors of HCV NS5B Polymerase. The Development and Pharmacophore of 2-Thienyl-5,6-dihydroxypyrimidine-4-carboxylic Acid
33. SAR and pharmacokinetic studies on phenethylamide inhibitors of the hepatitis C virus NS3/NS4A serine protease
34. Capped dipeptide phenethylamide inhibitors of the HCV NS3 protease
35. 3-Methoxy-1-phenylthio-1-propene as d1/ d3Synthon: Application for an Asymmetric Synthesis of (S)-(+)-Parasorbic Acid
36. Evolution, synthesis and SAR of tripeptide alpha-ketoacid inhibitors of the hepatitis C virus NS3/NS4A serine protease
37. Hepatitis C virus protease inhibitors: current progress and future challenges
38. Synthesis of Ethynylcyclopropanes from Epoxides
39. Sulfur-Functionalized Allyl Anions as Synthetic Building-Blocks
40. Sulfur as Supporting Element in Vinylcyclopropane Formation
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