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Researchers at the University of Patras in Greece have developed a mathematical model to study the nutrient distribution of avascular cancer tumors within an inhomogeneous environment. The model considers a cancerous cell colony as a continuous two-phase fluid with five bounded compartments, governed by mass conservation, Fick's diffusion law, and fluid mechanics principles. The study focuses on an oblate spheroidal tumor and investigates the effects of non-homogeneity in nutrient supply and consumption rates. The findings suggest that critical nutrient values are encountered within the interior of a thin layer, rather than at a single interface. The research has been peer-reviewed and published in the Journal of Engineering Mathematics. [Extracted from the article]

A recent study conducted by researchers at the University of Patras in Greece has found that the protein Ras suppressor-1 (RSU1) plays a significant role in lung adenocarcinoma (LUADC), a type of lung cancer. The study found that RSU1 protein expression is downregulated in LUADC tissue samples and serves as a prognostic indicator. Depletion of RSU1 in lung cancer cells promotes cell growth, motility, and epithelial to mesenchymal transition (EMT). The study suggests that RSU1 acts as a tumor suppressor in LUADC. This research has been peer-reviewed and provides valuable insights into the understanding and treatment of lung cancer. [Extracted from the article]

A recent study conducted by researchers at the University of Patras in Greece explores the progression of cervical intraepithelial neoplasia (CIN), which is the development of abnormal cells on the surface of the cervix caused by a human papillomavirus (HPV) infection. While most cases of CIN are resolved by the immune system, a small percentage can develop into cervical cancer if left untreated. The researchers developed a nonlinear mathematical model to describe the dynamics of epithelial, dysplastic, and immune cells, as well as viral particles in CIN progression. The study examines the impact of factors such as cervix geometry, immune response strength, and viral exposure frequency on dysplasia progression. This research is significant in light of the World Health Organization's Global Strategy for cervical cancer elimination by 2030. [Extracted from the article]

Keywords: Patras; Greece; Europe; Cancer; Cellular Structures; Extracellular Matrix; Extracellular Space; Health and Medicine; Oncology; Pathobiology EN Patras Greece Europe Cancer Cellular Structures Extracellular Matrix Extracellular Space Health and Medicine Oncology Pathobiology 1530 1530 1 10/30/23 20231031 NES 231031 2023 OCT 31 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- Investigators publish new report on Cancer. The main goal of this article is to highlight the vital functions of HA in cancer cell initiation and progression as well as HA-mediated paracrine interactions among cancer and stromal cells. Patras, Greece, Europe, Cancer, Cellular Structures, Extracellular Matrix, Extracellular Space, Health and Medicine, Oncology, Pathobiology. [Extracted from the article]

Keywords: Patras; Greece; Europe; Blood Protein Disorders; Cancer; Drugs and Therapies; Gangrene; Health and Medicine; Hematologic Diseases and Conditions; Hematology; Hemic and Lymphatic Diseases and Conditions; Hemorrhagic Disorders; Hemostatic Disorders; Immunoproliferative Disorders; Lymphoproliferative Disorders; Multiple Myeloma; Myeloma; Oncology; Paraproteinemias; Risk and Prevention; Vascular Diseases and Conditions EN Patras Greece Europe Blood Protein Disorders Cancer Drugs and Therapies Gangrene Health and Medicine Hematologic Diseases and Conditions Hematology Hemic and Lymphatic Diseases and Conditions Hemorrhagic Disorders Hemostatic Disorders Immunoproliferative Disorders Lymphoproliferative Disorders Multiple Myeloma Myeloma Oncology Paraproteinemias Risk and Prevention Vascular Diseases and Conditions 378 378 1 05/15/23 20230516 NES 230516 2023 MAY 15 (NewsRx) -- By a News Reporter-Staff News Editor at Hematology Week -- Investigators publish new report on Oncology - Multiple Myeloma. Keywords for this news article include: Patras, Greece, Europe, Blood Protein Disorders, Cancer, Drugs and Therapies, Gangrene, Health and Medicine, Hematologic Diseases and Conditions, Hematology, Hemic and Lymphatic Diseases and Conditions, Hemorrhagic Disorders, Hemostatic Disorders, Immunoproliferative Disorders, Lymphoproliferative Disorders, Multiple Myeloma, Myeloma, Oncology, Paraproteinemias, Risk and Prevention, Vascular Diseases and Conditions, University Hospital of Patras. [Extracted from the article]

The combined application of LPT-loaded nanorods and laser irradiation gave significantly higher cytotoxicity against the SK-BR-3 HER2 positive cancer cells compared to laser irradiation or LPT-loaded nanorods alone." Keywords: Patras; Greece; Europe; Antineoplastics; Breast Cancer; Cancer; Drugs and Therapies; EGFR Inhibitors; Emerging Technologies; Enzymes and Coenzymes; HER2 Inhibitors; Health and Medicine; Lapatinib Therapy; Nanorods; Nanotechnology; Oncology; Pharmaceuticals; Pharmacology; Pronase; Therapy; Tyrosine Kinase Inhibitors; Women's Health EN Patras Greece Europe Antineoplastics Breast Cancer Cancer Drugs and Therapies EGFR Inhibitors Emerging Technologies Enzymes and Coenzymes HER2 Inhibitors Health and Medicine Lapatinib Therapy Nanorods Nanotechnology Oncology Pharmaceuticals Pharmacology Pronase Therapy Tyrosine Kinase Inhibitors Women's Health 820 820 1 05/02/23 20230502 NES 230502 2023 MAY 2 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Investigators publish new report on Oncology - Breast Cancer. [Extracted from the article]

Keywords: Patras; Greece; Europe; Amino Acids; Arginine; Basic Amino Acids; Cancer; Diamino Amino Acids; Essential Amino Acids; Health and Medicine; Oncology; Prostate Cancer; Prostatic Neoplasms EN Patras Greece Europe Amino Acids Arginine Basic Amino Acids Cancer Diamino Amino Acids Essential Amino Acids Health and Medicine Oncology Prostate Cancer Prostatic Neoplasms 368 368 1 04/10/23 20230411 NES 230411 2023 APR 11 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- Researchers detail new data in Oncology - Prostate Cancer. Patras, Greece, Europe, Amino Acids, Arginine, Basic Amino Acids, Cancer, Diamino Amino Acids, Essential Amino Acids, Health and Medicine, Oncology, Prostate Cancer, Prostatic Neoplasms. [Extracted from the article]