1. Clustering Brain-Network Time Series by Riemannian Geometry
- Author
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David S. Wack, Jean M. Vettel, Sarah F. Muldoon, Henry E. Baidoo-Williams, Matthew Cieslak, Konstantinos Slavakis, Shiva Salsabilian, and Scott T. Grafton
- Subjects
Computer Networks and Communications ,Computer science ,020206 networking & telecommunications ,02 engineering and technology ,Fundamental theorem of Riemannian geometry ,Riemannian geometry ,Riemannian manifold ,Topology ,Manifold ,03 medical and health sciences ,symbols.namesake ,0302 clinical medicine ,Signal Processing ,0202 electrical engineering, electronic engineering, information engineering ,symbols ,Mathematics::Differential Geometry ,Information geometry ,Cluster analysis ,Exponential map (Riemannian geometry) ,030217 neurology & neurosurgery ,Information Systems ,Scalar curvature - Abstract
This paper advocates Riemannian multi-manifold modeling for network-wide time-series analysis: Dynamic brain-network data yield features which are viewed as points in or close to a union of a finite number of submanifolds of a Riemannian manifold. Distinguishing disparate time series amounts then to clustering multiple Riemannian submanifolds. To this end, two feature-generation schemes for network-wide dynamic time series are put forth. The first one is motivated by Granger-causality arguments and uses an auto-regressive moving average model to map low-rank linear vector subspaces, spanned by column vectors of observability matrices, to points into the Grassmann manifold. The second one utilizes (non-linear) dependencies among network nodes by introducing kernel-based partial correlations to generate points in the manifold of positive-definite matrices. Capitalizing on recently developed research on Riemannian-submanifold clustering, an algorithm is provided to differentiate time series based on their Riemannian-geometry properties. Extensive numerical tests on synthetic and real fMRI data demonstrate that the proposed framework outperforms classical and state-of-the-art techniques in clustering brain-network states/structures.
- Published
- 2018
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